PF01498 HTH_Tnp_Tc3_2 Transposase PF01609 DDE_Tnp_1 Transposase DDE domain PF01797 Y1_Tnp Transposase IS200 like PF02914 DDE_2 Bacteriophage Mu transposase PF11427 HTH_Tnp_Tc3_1 Tc3 transposase PF01359 Transposase_1 Transposase (partial DDE domain) PF02281 Dimer_Tnp_Tn5 Transposase Tn5 dimerisation domain PF02316 HTH_Tnp_Mu_1 Mu DNA-binding domain PF05699 Dimer_Tnp_hAT hAT family C-terminal dimerisation region PF09299 Mu-transpos_C Mu transposase, C-terminal PF14706 Tnp_DNA_bind Transposase DNA-binding PF17906 HTH_48 HTH domain in Mos1 transposase PF00872 Transposase_mut Transposase, Mutator family PF01526 DDE_Tnp_Tn3 Tn3 transposase DDE domain PF01527 HTH_Tnp_1 Transposase PF01548 DEDD_Tnp_IS110 Transposase PF02371 Transposase_20 Transposase IS116/IS110/IS902 family PF03400 DDE_Tnp_IS1 IS1 transposase PF04986 Y2_Tnp Putative transposase PF12017 Tnp_P_element Transposase protein PF01385 OrfB_IS605 Probable transposase PF01610 DDE_Tnp_ISL3 Transposase PF01710 HTH_Tnp_IS630 Transposase PF03004 Transposase_24 Plant transposase (Ptta/En/Spm family) PF03050 DDE_Tnp_IS66 Transposase IS66 family PF03108 DBD_Tnp_Mut MuDR family transposase PF03221 HTH_Tnp_Tc5 Tc5 transposase DNA-binding domain PF04693 DDE_Tnp_2 Archaeal putative transposase ISC1217 PF04754 Transposase_31 Putative transposase, YhgA-like PF04827 Plant_tran Plant transposon protein PF04937 DUF659 Protein of unknown function (DUF 659) PF05598 DUF772 Transposase domain (DUF772) PF07282 OrfB_Zn_ribbon Putative transposase DNA-binding domain PF07592 DDE_Tnp_ISAZ013 Rhodopirellula transposase DDE domain PF08483 IstB_IS21_ATP IstB-like ATP binding N-terminal PF08721 Tn7_Tnp_TnsA_C TnsA endonuclease C terminal PF08722 Tn7_Tnp_TnsA_N TnsA endonuclease N terminal PF10551 MULE MULE transposase domain PF12323 HTH_OrfB_IS605 Helix-turn-helix domain PF12596 Tnp_P_element_C 87kDa Transposase PF12760 Zn_Tnp_IS1595 Transposase zinc-ribbon domain PF12762 DDE_Tnp_IS1595 ISXO2-like transposase domain PF13005 zf-IS66 zinc-finger binding domain of transposase IS66 PF13006 Nterm_IS4 Insertion element 4 transposase N-terminal PF13007 LZ_Tnp_IS66 Transposase C of IS166 homeodomain PF13011 LZ_Tnp_IS481 leucine-zipper of insertion element IS481 PF13340 DUF4096 Putative transposase of IS4/5 family (DUF4096) PF13358 DDE_3 DDE superfamily endonuclease PF13359 DDE_Tnp_4 DDE superfamily endonuclease PF13542 HTH_Tnp_ISL3 Helix-turn-helix domain of transposase family ISL3 PF13546 DDE_5 DDE superfamily endonuclease PF13586 DDE_Tnp_1_2 Transposase DDE domain PF13610 DDE_Tnp_IS240 DDE domain PF13612 DDE_Tnp_1_3 Transposase DDE domain PF13613 HTH_Tnp_4 Helix-turn-helix of DDE superfamily endonuclease PF13700 DUF4158 Domain of unknown function (DUF4158) PF13701 DDE_Tnp_1_4 Transposase DDE domain group 1 PF13737 DDE_Tnp_1_5 Transposase DDE domain PF13751 DDE_Tnp_1_6 Transposase DDE domain PF13808 DDE_Tnp_1_assoc DDE_Tnp_1-associated PF13952 DUF4216 Domain of unknown function (DUF4216) PF13963 Transpos_assoc Transposase-associated domain PF14319 Zn_Tnp_IS91 Transposase zinc-binding domain PF14372 DUF4413 Domain of unknown function (DUF4413) PF14690 zf-ISL3 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PF01695 IstB_IS21 IstB-like ATP binding protein PF02992 Transposase_21 Transposase family tnp2 PF02994 Transposase_22 L1 transposable element RBD-like domain PF03017 Transposase_23 TNP1/EN/SPM transposase PF03184 DDE_1 DDE superfamily endonuclease PF04195 Transposase_28 Putative gypsy type transposon PF05717 TnpB_IS66 IS66 Orf2 like protein PF06782 UPF0236 Uncharacterised protein family (UPF0236) PF12784 PDDEXK_2 PD-(D/E)XK nuclease family transposase PF13022 HTH_Tnp_1_2 Helix-turn-helix of insertion element transposase PF13518 HTH_28 Helix-turn-helix domain PF13843 DDE_Tnp_1_7 Transposase IS4 PF18758 KDZ Kyakuja-Dileera-Zisupton transposase PF10683 DBD_Tnp_Hermes Hermes transposase DNA-binding domain PF09322 DUF1979 Domain of unknown function (DUF1979) PF10536 PMD Plant mobile domain PF11426 Tn7_TnsC_Int Tn7 transposition regulator TnsC PF12851 Tet_JBP Oxygenase domain of the 2OGFeDO superfamily PF04236 Transp_Tc5_C Tc5 transposase C-terminal domain PF06465 DUF1087 Domain of Unknown Function (DUF1087) PF06869 DUF1258 Protein of unknown function (DUF1258) PF13017 Maelstrom piRNA pathway germ-plasm component PF18717 CxC4 CxC4 like cysteine cluster associated with KDZ transposases PF18718 CxC5 CxC5 like cysteine cluster associated with KDZ transposases PF18721 CxC6 CxC6 like cysteine cluster associated with KDZ transposases PF18759 Plavaka Plavaka transposase PF18802 CxC1 CxC1 like cysteine cluster associated with KDZ transposases PF18803 CxC2 CxC2 like cysteine cluster associated with KDZ transposases PF18804 CxC3 CxC3 like cysteine cluster associated with KDZ transposases PF18866 CxC7 CxC7 like cysteine cluster associated with KDZ transposases PF05485 THAP THAP domain PF09039 HTH_Tnp_Mu_2 Mu DNA binding, I gamma subdomain PF17490 Tnp_22_dsRBD L1 transposable element dsRBD-like domain PF00665 rve Integrase core domain PF02892 zf-BED BED zinc finger PF03101 FAR1 FAR1 DNA-binding domain PF03811 Zn_Tnp_IS1 InsA N-terminal domain PF04218 CENP-B_N CENP-B N-terminal DNA-binding domain PF05225 HTH_psq helix-turn-helix, Psq domain PF11809 DUF3330 Domain of unknown function (DUF3330) PF13333 rve_2 Integrase core domain PF13683 rve_3 Integrase core domain PF13936 HTH_38 Helix-turn-helix domain PF14294 DUF4372 Domain of unknown function (DUF4372) PF00004 AAA ATPase family associated with various cellular activities (AAA) PF00005 ABC_tran ABC transporter PF00009 GTP_EFTU Elongation factor Tu GTP binding domain PF00012 HSP70 Hsp70 protein PF00024 PAN_1 PAN domain PF00057 Ldl_recept_a Low-density lipoprotein receptor domain class A PF00067 p450 Cytochrome P450 PF00069 Pkinase Protein kinase domain PF00072 Response_reg Response regulator receiver domain PF00075 RNase_H RNase H PF00076 RRM_1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PF00078 RVT_1 Reverse transcriptase (RNA-dependent DNA polymerase) PF00082 Peptidase_S8 Subtilase family PF00089 Trypsin Trypsin PF00098 zf-CCHC Zinc knuckle PF00106 adh_short short chain dehydrogenase PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain PF00120 Gln-synt_C Glutamine synthetase, catalytic domain PF00127 Copper-bind Copper binding proteins, plastocyanin/azurin family PF00145 DNA_methylase C-5 cytosine-specific DNA methylase PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain PF00149 Metallophos Calcineurin-like phosphoesterase PF00150 Cellulase Cellulase (glycosyl hydrolase family 5) PF00152 tRNA-synt_2 tRNA synthetases class II (D, K and N) PF00156 Pribosyltran Phosphoribosyl transferase domain PF00165 HTH_AraC Bacterial regulatory helix-turn-helix proteins, AraC family PF00170 bZIP_1 bZIP transcription factor PF00171 Aldedh Aldehyde dehydrogenase family PF00172 Zn_clus Fungal Zn(2)-Cys(6) binuclear cluster domain PF00196 GerE Bacterial regulatory proteins, luxR family PF00202 Aminotran_3 Aminotransferase class-III PF00209 SNF Sodium:neurotransmitter symporter family PF00226 DnaJ DnaJ domain PF00239 Resolvase Resolvase, N terminal domain PF00248 Aldo_ket_red Aldo/keto reductase family PF00266 Aminotran_5 Aminotransferase class-V PF00271 Helicase_C Helicase conserved C-terminal domain PF00292 PAX 'Paired box' domain PF00296 Bac_luciferase Luciferase-like monooxygenase PF00326 Peptidase_S9 Prolyl oligopeptidase family PF00348 polyprenyl_synt Polyprenyl synthetase PF00356 LacI Bacterial regulatory proteins, lacI family PF00376 MerR MerR family regulatory protein PF00385 Chromo Chromo (CHRromatin Organisation MOdifier) domain PF00392 GntR Bacterial regulatory proteins, gntR family PF00395 SLH S-layer homology domain PF00400 WD40 WD domain, G-beta repeat PF00403 HMA Heavy-metal-associated domain PF00404 Dockerin_1 Dockerin type I domain PF00439 Bromodomain Bromodomain PF00440 TetR_N Bacterial regulatory proteins, tetR family PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain PF00448 SRP54 SRP54-type protein, GTPase domain PF00474 SSF Sodium:solute symporter family PF00481 PP2C Protein phosphatase 2C PF00486 Trans_reg_C Transcriptional regulatory protein, C terminal PF00496 SBP_bac_5 Bacterial extracellular solute-binding proteins, family 5 Middle PF00497 SBP_bac_3 Bacterial extracellular solute-binding proteins, family 3 PF00501 AMP-binding AMP-binding enzyme PF00503 G-alpha G-protein alpha subunit PF00533 BRCT BRCA1 C Terminus (BRCT) domain PF00534 Glycos_transf_1 Glycosyl transferases group 1 PF00535 Glycos_transf_2 Glycosyl transferase family 2 PF00550 PP-binding Phosphopantetheine attachment site PF00563 EAL EAL domain PF00564 PB1 PB1 domain PF00565 SNase Staphylococcal nuclease homologue PF00582 Usp Universal stress protein family PF00588 SpoU_methylase SpoU rRNA Methylase family PF00589 Phage_integrase Phage integrase family PF00593 TonB_dep_Rec TonB dependent receptor PF00646 F-box F-box domain PF00648 Peptidase_C2 Calpain family cysteine protease PF00650 CRAL_TRIO CRAL/TRIO domain PF00654 Voltage_CLC Voltage gated chloride channel PF00656 Peptidase_C14 Caspase domain PF00668 Condensation Condensation domain PF00704 Glyco_hydro_18 Glycosyl hydrolases family 18 PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein PF00753 Lactamase_B Metallo-beta-lactamase superfamily PF00756 Esterase Putative esterase PF00805 Pentapeptide Pentapeptide repeats (8 copies) PF00847 AP2 AP2 domain PF00856 SET SET domain PF00857 Isochorismatase Isochorismatase family PF00884 Sulfatase Sulfatase PF00903 Glyoxalase Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PF00905 Transpeptidase Penicillin binding protein transpeptidase domain PF00929 RNase_T Exonuclease PF00931 NB-ARC NB-ARC domain PF00999 Na_H_Exchanger Sodium/hydrogen exchanger family PF01019 G_glu_transpept Gamma-glutamyltranspeptidase PF01022 HTH_5 Bacterial regulatory protein, arsR family PF01042 Ribonuc_L-PSP Endoribonuclease L-PSP PF01075 Glyco_transf_9 Glycosyltransferase family 9 (heptosyltransferase) PF01145 Band_7 SPFH domain / Band 7 family PF01156 IU_nuc_hydro Inosine-uridine preferring nucleoside hydrolase PF01161 PBP Phosphatidylethanolamine-binding protein PF01209 Ubie_methyltran ubiE/COQ5 methyltransferase family PF01243 Putative_PNPOx Pyridoxamine 5'-phosphate oxidase PF01261 AP_endonuc_2 Xylose isomerase-like TIM barrel PF01266 DAO FAD dependent oxidoreductase PF01288 HPPK 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PF01302 CAP_GLY CAP-Gly domain PF01325 Fe_dep_repress Iron dependent repressor, N-terminal DNA binding domain PF01344 Kelch_1 Kelch motif PF01363 FYVE FYVE zinc finger PF01370 Epimerase NAD dependent epimerase/dehydratase family PF01371 Trp_repressor Trp repressor protein PF01381 HTH_3 Helix-turn-helix PF01397 Terpene_synth Terpene synthase, N-terminal domain PF01402 RHH_1 Ribbon-helix-helix protein, copG family PF01408 GFO_IDH_MocA Oxidoreductase family, NAD-binding Rossmann fold PF01419 Jacalin Jacalin-like lectin domain PF01423 LSM LSM domain PF01425 Amidase Amidase PF01476 LysM LysM domain PF01522 Polysacc_deac_1 Polysaccharide deacetylase PF01547 SBP_bac_1 Bacterial extracellular solute-binding protein PF01558 POR Pyruvate ferredoxin/flavodoxin oxidoreductase PF01636 APH Phosphotransferase enzyme family PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase PF01738 DLH Dienelactone hydrolase family PF01798 Nop snoRNA binding domain, fibrillarin PF01844 HNH HNH endonuclease PF01850 PIN PIN domain PF01855 POR_N Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PF01872 RibD_C RibD C-terminal domain PF01882 DUF58 Protein of unknown function DUF58 PF01936 NYN NYN domain PF01966 HD HD domain PF02086 MethyltransfD12 D12 class N6 adenine-specific DNA methyltransferase PF02146 SIR2 Sir2 family PF02321 OEP Outer membrane efflux protein PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain PF02384 N6_Mtase N-6 DNA Methylase PF02423 OCD_Mu_crystall Ornithine cyclodeaminase/mu-crystallin family PF02486 Rep_trans Replication initiation factor PF02492 cobW CobW/HypB/UreG, nucleotide-binding domain PF02515 CoA_transf_3 CoA-transferase family III PF02534 T4SS-DNA_transf Type IV secretory system Conjugative DNA transfer PF02563 Poly_export Polysaccharide biosynthesis/export protein PF02566 OsmC OsmC-like protein PF02583 Trns_repr_metal Metal-sensitive transcriptional repressor PF02586 SRAP SOS response associated peptidase (SRAP) PF02590 SPOUT_MTase Predicted SPOUT methyltransferase PF02627 CMD Carboxymuconolactone decarboxylase family PF02661 Fic Fic/DOC family PF02678 Pirin Pirin PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain PF02796 HTH_7 Helix-turn-helix domain of resolvase PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain PF02811 PHP PHP domain PF02894 GFO_IDH_MocA_C Oxidoreductase family, C-terminal alpha/beta domain PF02899 Phage_int_SAM_1 Phage integrase, N-terminal SAM-like domain PF02902 Peptidase_C48 Ulp1 protease family, C-terminal catalytic domain PF02909 TetR_C_1 Tetracyclin repressor-like, C-terminal domain PF02920 Integrase_DNA DNA binding domain of tn916 integrase PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2 PF02954 HTH_8 Bacterial regulatory protein, Fis family PF02978 SRP_SPB Signal peptide binding domain PF03009 GDPD Glycerophosphoryl diester phosphodiesterase family PF03087 DUF241 Arabidopsis protein of unknown function PF03167 UDG Uracil DNA glycosylase superfamily PF03222 Trp_Tyr_perm Tryptophan/tyrosine permease family PF03237 Terminase_6 Terminase-like family PF03377 TAL_effector TAL effector repeat PF03428 RP-C Replication protein C N-terminal domain PF03457 HA Helicase associated domain PF03473 MOSC MOSC domain PF03564 DUF1759 Protein of unknown function (DUF1759) PF03567 Sulfotransfer_2 Sulfotransferase family PF03600 CitMHS Citrate transporter PF03631 Virul_fac_BrkB Virulence factor BrkB PF03686 UPF0146 Uncharacterised protein family (UPF0146) PF03692 CxxCxxCC Putative zinc- or iron-chelating domain PF03717 PBP_dimer Penicillin-binding Protein dimerisation domain PF03732 Retrotrans_gag Retrotransposon gag protein PF03747 ADP_ribosyl_GH ADP-ribosylglycohydrolase PF03807 F420_oxidored NADP oxidoreductase coenzyme F420-dependent PF03816 LytR_cpsA_psr Cell envelope-related transcriptional attenuator domain PF03865 ShlB Haemolysin secretion/activation protein ShlB/FhaC/HecB PF03934 T2SSK Type II secretion system (T2SS), protein K PF03936 Terpene_synth_C Terpene synthase family, metal binding domain PF04025 DUF370 Domain of unknown function (DUF370) PF04045 P34-Arc Arp2/3 complex, 34 kD subunit p34-Arc PF04055 Radical_SAM Radical SAM superfamily PF04098 Rad52_Rad22 Rad52/22 family double-strand break repair protein PF04102 SlyX SlyX PF04183 IucA_IucC IucA / IucC family PF04219 DUF413 Protein of unknown function, DUF PF04230 PS_pyruv_trans Polysaccharide pyruvyl transferase PF04250 DUF429 Protein of unknown function (DUF429) PF04297 UPF0122 Putative helix-turn-helix protein, YlxM / p13 like PF04321 RmlD_sub_bind RmlD substrate binding domain PF04326 AlbA_2 Putative DNA-binding domain PF04365 BrnT_toxin Ribonuclease toxin, BrnT, of type II toxin-antitoxin system PF04434 SWIM SWIM zinc finger PF04539 Sigma70_r3 Sigma-70 region 3 PF04542 Sigma70_r2 Sigma-70 region 2 PF04545 Sigma70_r4 Sigma-70, region 4 PF04576 Zein-binding Zein-binding PF04616 Glyco_hydro_43 Glycosyl hydrolases family 43 PF04740 LXG LXG domain of WXG superfamily PF04851 ResIII Type III restriction enzyme, res subunit PF04879 Molybdop_Fe4S4 Molybdopterin oxidoreductase Fe4S4 domain PF04970 LRAT Lecithin retinol acyltransferase PF04993 TfoX_N TfoX N-terminal domain PF05015 HigB-like_toxin RelE-like toxin of type II toxin-antitoxin system HigB PF05033 Pre-SET Pre-SET motif PF05043 Mga Mga helix-turn-helix domain PF05119 Terminase_4 Phage terminase, small subunit PF05135 Phage_connect_1 Phage gp6-like head-tail connector protein PF05198 IF3_N Translation initiation factor IF-3, N-terminal domain PF05343 Peptidase_M42 M42 glutamyl aminopeptidase PF05344 DUF746 Domain of Unknown Function (DUF746) PF05345 He_PIG Putative Ig domain PF05368 NmrA NmrA-like family PF05380 Peptidase_A17 Pao retrotransposon peptidase PF05420 BCSC_C Cellulose synthase operon protein C C-terminus (BCSC_C) PF05534 HicB HicB family PF05585 DUF1758 Putative peptidase (DUF1758) PF05621 TniB Bacterial TniB protein PF05685 Uma2 Putative restriction endonuclease PF05712 MRG MRG PF05713 MobC Bacterial mobilisation protein (MobC) PF05726 Pirin_C Pirin C-terminal cupin domain PF05853 BKACE beta-keto acid cleavage enzyme PF05876 Terminase_GpA Phage terminase large subunit (GpA) PF05930 Phage_AlpA Prophage CP4-57 regulatory protein (AlpA) PF05940 NnrS NnrS protein PF05973 Gp49 Phage derived protein Gp49-like (DUF891) PF06005 ZapB Cell division protein ZapB PF06051 DUF928 Domain of Unknown Function (DUF928) PF06056 Terminase_5 Putative ATPase subunit of terminase (gpP-like) PF06133 Com_YlbF Control of competence regulator ComK, YlbF/YmcA PF06156 YabA Initiation control protein YabA PF06157 DUF973 Protein of unknown function (DUF973) PF06250 YhcG_C YhcG PDDEXK nuclease domain PF06262 Zincin_1 Zincin-like metallopeptidase PF06276 FhuF Ferric iron reductase FhuF-like transporter PF06314 ADC Acetoacetate decarboxylase (ADC) PF06482 Endostatin Collagenase NC10 and Endostatin PF06504 RepC Replication protein C (RepC) PF06527 TniQ TniQ PF06619 DUF1149 Protein of unknown function (DUF1149) PF06627 DUF1153 Protein of unknown function (DUF1153) PF06723 MreB_Mbl MreB/Mbl protein PF06819 Arc_PepC Archaeal Peptidase A24 C-terminal Domain PF07037 DUF1323 Putative transcription regulator (DUF1323) PF07042 TrfA TrfA protein PF07228 SpoIIE Stage II sporulation protein E (SpoIIE) PF07261 DnaB_2 Replication initiation and membrane attachment PF07308 DUF1456 Protein of unknown function (DUF1456) PF07332 Phage_holin_3_6 Putative Actinobacterial Holin-X, holin superfamily III PF07453 NUMOD1 NUMOD1 domain PF07498 Rho_N Rho termination factor, N-terminal domain PF07508 Recombinase Recombinase PF07517 SecA_DEAD SecA DEAD-like domain PF07669 Eco57I Eco57I restriction-modification methylase PF07683 CobW_C Cobalamin synthesis protein cobW C-terminal domain PF07690 MFS_1 Major Facilitator Superfamily PF07691 PA14 PA14 domain PF07695 7TMR-DISM_7TM 7TM diverse intracellular signalling PF07696 7TMR-DISMED2 7TMR-DISM extracellular 2 PF07727 RVT_2 Reverse transcriptase (RNA-dependent DNA polymerase) PF07729 FCD FCD domain PF07748 Glyco_hydro_38C Glycosyl hydrolases family 38 C-terminal domain PF07804 HipA_C HipA-like C-terminal domain PF07859 Abhydrolase_3 alpha/beta hydrolase fold PF07920 DUF1684 Protein of unknown function (DUF1684) PF07927 HicA_toxin HicA toxin of bacterial toxin-antitoxin, PF07929 PRiA4_ORF3 Plasmid pRiA4b ORF-3-like protein PF07944 Glyco_hydro_127 Beta-L-arabinofuranosidase, GH127 PF07963 N_methyl Prokaryotic N-terminal methylation motif PF07980 SusD_RagB SusD family PF07993 NAD_binding_4 Male sterility protein PF08022 FAD_binding_8 FAD-binding domain PF08032 SpoU_sub_bind RNA 2'-O ribose methyltransferase substrate binding PF08220 HTH_DeoR DeoR-like helix-turn-helix domain PF08238 Sel1 Sel1 repeat PF08239 SH3_3 Bacterial SH3 domain PF08241 Methyltransf_11 Methyltransferase domain PF08279 HTH_11 HTH domain PF08281 Sigma70_r4_2 Sigma-70, region 4 PF08282 Hydrolase_3 haloacid dehalogenase-like hydrolase PF08299 Bac_DnaA_C Bacterial dnaA protein helix-turn-helix PF08388 GIIM Group II intron, maturase-specific domain PF08542 Rep_fac_C Replication factor C C-terminal domain PF08670 MEKHLA MEKHLA domain PF08681 DUF1778 Protein of unknown function (DUF1778) PF08704 GCD14 tRNA methyltransferase complex GCD14 subunit PF08768 DUF1794 Domain of unknown function (DUF1794) PF08845 SymE_toxin Toxin SymE, type I toxin-antitoxin system PF08881 CVNH CVNH domain PF08897 DUF1841 Domain of unknown function (DUF1841) PF08961 NRBF2 Nuclear receptor-binding factor 2, autophagy regulator PF09000 Cytotoxic Cytotoxic PF09035 Tn916-Xis Excisionase from transposon Tn916 PF09077 Phage-MuB_C Mu B transposition protein, C terminal PF09278 MerR-DNA-bind MerR, DNA binding PF09279 EF-hand_like Phosphoinositide-specific phospholipase C, efhand-like PF09339 HTH_IclR IclR helix-turn-helix domain PF09344 Cas_CT1975 CT1975-like protein PF09366 DUF1997 Protein of unknown function (DUF1997) PF09388 SpoOE-like Spo0E like sporulation regulatory protein PF09391 DUF2000 Protein of unknown function (DUF2000) PF09455 Cas_DxTHG CRISPR-associated (Cas) DxTHG family PF09485 CRISPR_Cse2 CRISPR-associated protein Cse2 (CRISPR_cse2) PF09607 BrkDBD Brinker DNA-binding domain PF09633 DUF2023 Protein of unknown function (DUF2023) PF09722 DUF2384 Protein of unknown function (DUF2384) PF09811 Yae1_N Essential protein Yae1, N terminal PF09827 CRISPR_Cas2 CRISPR associated protein Cas2 PF09853 DUF2080 Putative transposon-encoded protein (DUF2080) PF09862 DUF2089 Protein of unknown function (DUF2089) PF09958 DUF2192 Uncharacterized protein conserved in archaea (DUF2192) PF10038 DUF2274 Protein of unknown function (DUF2274) PF10263 SprT-like SprT-like family PF10531 SLBB SLBB domain PF10561 UPF0565 Uncharacterised protein family UPF0565 PF10592 AIPR AIPR protein PF10668 Phage_terminase Phage terminase small subunit PF10901 DUF2690 Protein of unknown function (DUF2690) PF10921 DUF2710 Protein of unknown function (DUF2710) PF10935 DUF2637 Protein of unknown function (DUF2637) PF11000 DUF2840 Protein of unknown function (DUF2840) PF11103 DUF2887 Protein of unknown function (DUF2887) PF11149 DUF2924 Protein of unknown function (DUF2924) PF11171 DUF2958 Protein of unknown function (DUF2958) PF11225 DUF3024 Protein of unknown function (DUF3024) PF11251 DUF3050 Protein of unknown function (DUF3050) PF11272 DUF3072 Protein of unknown function (DUF3072) PF11726 Inovirus_Gp2 Inovirus Gp2 PF11740 KfrA_N Plasmid replication region DNA-binding N-term PF11776 RcnB Nickel/cobalt transporter regulator PF11800 RP-C_C Replication protein C C-terminal region PF11843 DUF3363 Protein of unknown function (DUF3363) PF11867 DUF3387 Domain of unknown function (DUF3387) PF11888 DUF3408 Protein of unknown function (DUF3408) PF11907 DUF3427 Domain of unknown function (DUF3427) PF12002 MgsA_C MgsA AAA+ ATPase C terminal PF12013 OrsD Orsellinic acid/F9775 biosynthesis cluster protein D PF12146 Hydrolase_4 Serine aminopeptidase, S33 PF12167 Arm-DNA-bind_2 Arm DNA-binding domain PF12375 DUF3653 Phage protein PF12571 DUF3751 Phage tail-collar fibre protein PF12642 TpcC Conjugative transposon protein TcpC PF12686 DUF3800 Protein of unknown function (DUF3800) PF12728 HTH_17 Helix-turn-helix domain PF12759 HTH_Tnp_IS1 InsA C-terminal domain PF12776 Myb_DNA-bind_3 Myb/SANT-like DNA-binding domain PF12796 Ank_2 Ankyrin repeats (3 copies) PF12802 MarR_2 MarR family PF12833 HTH_18 Helix-turn-helix domain PF12836 HHH_3 Helix-hairpin-helix motif PF12848 ABC_tran_Xtn ABC transporter PF12940 RAG1 Recombination-activation protein 1 (RAG1), recombinase PF12950 TaqI_C TaqI-like C-terminal specificity domain PF13091 PLDc_2 PLD-like domain PF13102 Phage_int_SAM_5 Phage integrase SAM-like domain PF13148 DUF3987 Protein of unknown function (DUF3987) PF13181 TPR_8 Tetratricopeptide repeat PF13193 AMP-binding_C AMP-binding enzyme C-terminal domain PF13231 PMT_2 Dolichyl-phosphate-mannose-protein mannosyltransferase PF13274 DUF4065 Protein of unknown function (DUF4065) PF13276 HTH_21 HTH-like domain PF13302 Acetyltransf_3 Acetyltransferase (GNAT) domain PF13310 Virulence_RhuM Virulence protein RhuM family PF13353 Fer4_12 4Fe-4S single cluster domain PF13356 Arm-DNA-bind_3 Arm DNA-binding domain PF13374 TPR_10 Tetratricopeptide repeat PF13384 HTH_23 Homeodomain-like domain PF13401 AAA_22 AAA domain PF13404 HTH_AsnC-type AsnC-type helix-turn-helix domain PF13408 Zn_ribbon_recom Recombinase zinc beta ribbon domain PF13411 MerR_1 MerR HTH family regulatory protein PF13412 HTH_24 Winged helix-turn-helix DNA-binding PF13415 Kelch_3 Galactose oxidase, central domain PF13432 TPR_16 Tetratricopeptide repeat PF13439 Glyco_transf_4 Glycosyltransferase Family 4 PF13443 HTH_26 Cro/C1-type HTH DNA-binding domain PF13450 NAD_binding_8 NAD(P)-binding Rossmann-like domain PF13452 MaoC_dehydrat_N N-terminal half of MaoC dehydratase PF13456 RVT_3 Reverse transcriptase-like PF13458 Peripla_BP_6 Periplasmic binding protein PF13460 NAD_binding_10 NAD(P)H-binding PF13472 Lipase_GDSL_2 GDSL-like Lipase/Acylhydrolase family PF13474 SnoaL_3 SnoaL-like domain PF13482 RNase_H_2 RNase_H superfamily PF13489 Methyltransf_23 Methyltransferase domain PF13495 Phage_int_SAM_4 Phage integrase, N-terminal SAM-like domain PF13505 OMP_b-brl Outer membrane protein beta-barrel domain PF13508 Acetyltransf_7 Acetyltransferase (GNAT) domain PF13517 VCBS Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PF13520 AA_permease_2 Amino acid permease PF13523 Acetyltransf_8 Acetyltransferase (GNAT) domain PF13541 ChlI Subunit ChlI of Mg-chelatase PF13551 HTH_29 Winged helix-turn helix PF13556 HTH_30 PucR C-terminal helix-turn-helix domain PF13560 HTH_31 Helix-turn-helix domain PF13561 adh_short_C2 Enoyl-(Acyl carrier protein) reductase PF13565 HTH_32 Homeodomain-like domain PF13572 DUF4134 Domain of unknown function (DUF4134) PF13592 HTH_33 Winged helix-turn helix PF13632 Glyco_trans_2_3 Glycosyl transferase family group 2 PF13641 Glyco_tranf_2_3 Glycosyltransferase like family 2 PF13643 DUF4145 Domain of unknown function (DUF4145) PF13646 HEAT_2 HEAT repeats PF13649 Methyltransf_25 Methyltransferase domain PF13655 RVT_N N-terminal domain of reverse transcriptase PF13657 Couple_hipA HipA N-terminal domain PF13669 Glyoxalase_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PF13699 DUF4157 Domain of unknown function (DUF4157) PF13704 Glyco_tranf_2_4 Glycosyl transferase family 2 PF13711 DUF4160 Domain of unknown function (DUF4160) PF13749 HATPase_c_4 Putative ATP-dependent DNA helicase recG C-terminal PF13780 DUF4176 Domain of unknown function (DUF4176) PF13817 DDE_Tnp_IS66_C IS66 C-terminal element PF13842 Tnp_zf-ribbon_2 DDE_Tnp_1-like zinc-ribbon PF13847 Methyltransf_31 Methyltransferase domain PF13873 Myb_DNA-bind_5 Myb/SANT-like DNA-binding domain PF13930 Endonuclea_NS_2 DNA/RNA non-specific endonuclease PF13948 DUF4215 Domain of unknown function (DUF4215) PF13960 DUF4218 Domain of unknown function (DUF4218) PF14021 TNT Tuberculosis necrotizing toxin PF14024 DUF4240 Protein of unknown function (DUF4240) PF14104 DUF4277 Domain of unknown function (DUF4277) PF14111 DUF4283 Domain of unknown function (DUF4283) PF14198 TnpV Transposon-encoded protein TnpV PF14200 RicinB_lectin_2 Ricin-type beta-trefoil lectin domain-like PF14202 TnpW Transposon-encoded protein TnpW PF14210 DUF4322 Domain of unknown function (DUF4322) PF14236 DUF4338 Domain of unknown function (DUF4338) PF14261 DUF4351 Domain of unknown function (DUF4351) PF14291 DUF4371 Domain of unknown function (DUF4371) PF14392 zf-CCHC_4 Zinc knuckle PF14399 BtrH_N Butirosin biosynthesis protein H, N-terminal PF14411 LHH A nuclease of the HNH/ENDO VII superfamily with conserved LHH PF14414 WHH A nuclease of the HNH/ENDO VII superfamily with conserved WHH PF14436 EndoU_bacteria Bacterial EndoU nuclease PF14449 PT-TG Pre-toxin TG PF14472 DUF4429 Domain of unknown function (DUF4429) PF14516 AAA_35 AAA-like domain PF14529 Exo_endo_phos_2 Endonuclease-reverse transcriptase PF14534 DUF4440 Domain of unknown function (DUF4440) PF14559 TPR_19 Tetratricopeptide repeat PF14657 Arm-DNA-bind_4 Arm DNA-binding domain PF14659 Phage_int_SAM_3 Phage integrase, N-terminal SAM-like domain PF14714 KH_dom-like KH-domain-like of EngA bacterial GTPase enzymes, C-terminal PF14748 P5CR_dimer Pyrroline-5-carboxylate reductase dimerisation PF14801 GCD14_N tRNA methyltransferase complex GCD14 subunit N-term PF15288 zf-CCHC_6 Zinc knuckle PF15430 SVWC Single domain von Willebrand factor type C PF15534 Ntox35 Bacterial toxin 35 PF15540 Ntox47 Bacterial toxin 47 PF15542 Ntox50 Bacterial toxin 50 PF15637 Tox-HNH-HHH HNH/Endo VII superfamily nuclease toxin with a HHH motif PF15978 TnsD Tn7-like transposition protein D PF16087 DUF4817 Helix-turn-helix domain (DUF4817) PF16193 AAA_assoc_2 AAA C-terminal domain PF16197 KAsynt_C_assoc Ketoacyl-synthetase C-terminal extension PF16258 DUF4912 Domain of unknown function (DUF4912) PF16286 DUF4932 Domain of unknown function (DUF4932) PF16369 GH43_C C-terminal lipocalin-like domain PF16472 DUF5050 Domain of unknown function (DUF5050) PF17289 Terminase_6C Terminase RNaseH-like domain PF17293 Arm-DNA-bind_5 Arm DNA-binding domain PF17342 DUF5372 Family of unknown function (DUF5372) PF17489 Tnp_22_trimer L1 transposable element trimerization domain PF17517 IgGFc_binding IgGFc binding protein PF17761 DUF1016_N DUF1016 N-terminal domain PF17874 TPR_MalT MalT-like TPR region PF17908 APAF1_C APAF-1 helical domain PF17917 RT_RNaseH RNase H-like domain found in reverse transcriptase PF17918 TetR_C_15 Tetracyclin repressor-like, C-terminal domain PF17919 RT_RNaseH_2 RNase H-like domain found in reverse transcriptase PF17921 Integrase_H2C2 Integrase zinc binding domain PF17938 TetR_C_29 Tetracyclin repressor-like, C-terminal domain PF17957 Big_7 Bacterial Ig domain PF18029 Glyoxalase_6 Glyoxalase-like domain PF18106 Rol_Rep_N Rolling Circle replication initiation protein N-terminal domain PF18107 HTH_ABP1_N Fission yeast centromere protein N-terminal domain PF18143 HAD_SAK_2 HAD domain in Swiss Army Knife RNA repair proteins PF18155 pPIWI_RE_Z pPIWI RE three-gene island domain Z PF18158 AidB_N Adaptive response protein AidB N-terminal domain PF18159 S_4TM SMODS-associating 4TM effector domain PF18291 HU-HIG HU domain fused to wHTH, Ig, or Glycine-rich motif PF18555 MobL MobL relaxases PF18602 Rap1a Rap1a immunity proteins PF18623 TnsE_C TnsE C-terminal domain PF18701 DUF5641 Family of unknown function (DUF5641) PF18742 DpnII-MboI REase_DpnII-MboI PF18812 PBECR3 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 PF00552 IN_DBD_C Integrase DNA binding domain