# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Reticulon PF02453.17 AAFJ01000010_00004 - 0.011 15.7 3.4 0.011 15.7 3.4 1.2 1 0 0 1 1 1 0 Reticulon TK PF00265.18 AAFJ01000010_00005 - 7e-20 71.6 1.2 1.6e-19 70.5 1.2 1.6 1 1 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 AAFJ01000010_00005 - 0.003 17.6 0.3 0.004 17.2 0.3 1.2 1 0 0 1 1 1 1 AAA domain Terminase_6 PF03237.15 AAFJ01000010_00005 - 0.0088 15.7 0.4 0.03 14.0 0.4 1.9 1 1 0 1 1 1 1 Terminase-like family FcoT PF10862.8 AAFJ01000010_00006 - 0.031 13.9 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 FcoT-like thioesterase domain ECH_2 PF16113.5 AAFJ01000010_00006 - 0.044 13.3 0.5 0.045 13.3 0.5 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase EF-hand_7 PF13499.6 AAFJ01000010_00006 - 0.068 13.6 0.2 2.6 8.5 0.2 2.1 1 1 0 1 1 1 0 EF-hand domain pair DUF3973 PF13119.6 AAFJ01000010_00007 - 0.088 12.9 2.7 0.35 11.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Toprim_2 PF13155.6 AAFJ01000010_00010 - 2.2e-11 44.0 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.6 AAFJ01000010_00010 - 4.2e-05 23.8 0.0 8.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.20 AAFJ01000010_00010 - 0.0061 16.4 0.1 0.037 13.8 0.1 2.2 2 0 0 2 2 2 1 CHC2 zinc finger DUF3854 PF12965.7 AAFJ01000010_00010 - 0.094 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) CSN8_PSD8_EIF3K PF10075.9 AAFJ01000010_00011 - 0.31 11.0 4.2 0.29 11.1 0.8 2.2 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family Peptidase_C39 PF03412.15 AAFJ01000010_00015 - 2.5e-17 62.9 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 AAFJ01000010_00015 - 3e-05 24.0 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Phage_integrase PF00589.22 AAFJ01000010_00017 - 2.8e-20 72.8 2.1 4.4e-20 72.2 2.1 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAFJ01000010_00017 - 5.5e-05 23.4 2.7 0.081 13.2 0.1 3.1 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AAFJ01000010_00017 - 0.00022 21.5 8.0 0.00022 21.5 8.0 2.7 2 2 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 AAFJ01000010_00017 - 0.0026 18.2 5.5 0.0026 18.2 5.5 2.5 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 AAFJ01000010_00017 - 0.0035 17.5 0.4 0.0067 16.5 0.4 1.5 1 0 0 1 1 1 1 Integrase Phage_int_SAM_6 PF18644.1 AAFJ01000010_00017 - 3.7 7.6 16.4 0.77 9.8 0.9 3.2 3 1 1 4 4 4 0 Phage integrase SAM-like domain HMG-CoA_red PF00368.18 AAFJ01000010_00018 - 0.083 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase WGR PF05406.15 AAFJ01000010_00019 - 0.00012 22.0 0.3 0.00014 21.8 0.3 1.1 1 0 0 1 1 1 1 WGR domain Latarcin PF10279.9 AAFJ01000010_00019 - 0.01 16.2 0.1 0.015 15.7 0.1 1.2 1 0 0 1 1 1 0 Latarcin precursor Tantalus PF15386.6 AAFJ01000010_00019 - 0.047 13.8 0.1 0.047 13.8 0.1 1.9 1 1 1 2 2 2 0 Drosophila Tantalus-like PPR_2 PF13041.6 AAFJ01000010_00019 - 0.14 12.4 0.9 0.23 11.7 0.9 1.4 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.20 AAFJ01000010_00019 - 0.23 11.8 1.6 0.31 11.4 0.7 1.6 2 0 0 2 2 2 0 PPR repeat HD PF01966.22 AAFJ01000010_00021 - 1.8e-10 41.1 0.9 3.6e-10 40.1 0.9 1.6 1 0 0 1 1 1 1 HD domain HD_6 PF18019.1 AAFJ01000010_00021 - 0.029 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 HD domain TrwB_AAD_bind PF10412.9 AAFJ01000010_00022 - 4e-17 62.2 0.0 6.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 AAFJ01000010_00022 - 2e-15 56.6 0.5 2.7e-15 56.2 0.5 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AAFJ01000010_00022 - 1.3e-10 41.3 0.1 2.7e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG DUF87 PF01935.17 AAFJ01000010_00022 - 1.2e-05 25.6 0.5 2.9e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_10 PF12846.7 AAFJ01000010_00022 - 1.3e-05 24.3 0.3 0.012 14.5 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain DUF853 PF05872.12 AAFJ01000010_00022 - 0.0034 16.0 0.0 0.0076 14.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 AAFJ01000010_00022 - 0.007 16.6 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAFJ01000010_00022 - 0.016 15.6 0.0 0.078 13.4 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 AAFJ01000010_00022 - 0.018 14.9 0.1 0.064 13.2 0.1 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 AAFJ01000010_00022 - 0.034 14.7 0.1 0.097 13.2 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 AAFJ01000010_00022 - 0.042 13.1 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF1548 PF07579.11 AAFJ01000010_00022 - 0.11 12.8 1.9 0.44 10.9 0.2 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) FtsK_SpoIIIE PF01580.18 AAFJ01000010_00022 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArlS_N PF18719.1 AAFJ01000010_00022 - 0.91 9.7 4.0 2.1 8.6 0.2 2.5 2 1 0 2 2 2 0 ArlS sensor domain OSTMP1 PF09777.9 AAFJ01000010_00023 - 1.2 8.5 3.2 6.1 6.2 0.3 2.3 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor MnmE_helical PF12631.7 AAFJ01000010_00024 - 0.44 10.7 1.7 0.7 10.0 1.7 1.5 1 1 0 1 1 1 0 MnmE helical domain HTH_3 PF01381.22 AAFJ01000010_00025 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAFJ01000010_00025 - 1.2e-08 34.8 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AAFJ01000010_00025 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain APG12 PF04110.13 AAFJ01000010_00025 - 0.1 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 AAA_19 PF13245.6 AAFJ01000010_00026 - 6.3e-14 52.5 0.2 4.6e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 AAFJ01000010_00026 - 6.5e-12 45.6 17.8 8.3e-10 38.7 1.7 4.0 1 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 AAFJ01000010_00026 - 6.1e-11 42.5 0.3 2.8e-05 24.0 0.1 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 AAFJ01000010_00026 - 4.3e-10 39.5 16.6 4.7e-10 39.4 12.7 2.5 1 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AAFJ01000010_00026 - 6e-09 35.6 0.0 4.8e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AAFJ01000010_00026 - 8.1e-06 25.7 0.0 0.0045 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 AAFJ01000010_00026 - 0.00049 19.6 0.2 0.47 9.9 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein DUF2075 PF09848.9 AAFJ01000010_00026 - 0.02 14.2 0.3 3.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Peptidase_M6 PF05547.11 AAFJ01000010_00026 - 0.025 12.9 0.1 0.037 12.4 0.1 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Helicase_RecD PF05127.14 AAFJ01000010_00026 - 0.04 13.8 0.7 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Helicase AAA_11 PF13086.6 AAFJ01000010_00026 - 0.11 12.3 0.5 19 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 AAFJ01000010_00026 - 0.34 10.9 8.2 0.065 13.2 1.8 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Thioredoxin_7 PF13899.6 AAFJ01000010_00027 - 4.1e-05 23.7 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AAFJ01000010_00027 - 0.00038 20.9 0.4 0.0011 19.4 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 AAFJ01000010_00027 - 0.047 13.6 0.2 0.055 13.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF255 Redoxin PF08534.10 AAFJ01000010_00027 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin TrbC_Ftype PF09673.10 AAFJ01000010_00028 - 2e-16 60.0 0.0 3.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein DUF1694 PF07997.11 AAFJ01000010_00028 - 0.0015 18.6 0.5 0.0085 16.2 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1694) DUF3502 PF12010.8 AAFJ01000010_00028 - 0.028 15.0 2.0 0.028 15.0 2.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3502) Thioredoxin PF00085.20 AAFJ01000010_00028 - 0.039 14.0 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 Thioredoxin TraU PF06834.11 AAFJ01000010_00029 - 9.6e-97 323.9 0.0 1.1e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 TraU protein RhoGAP PF00620.27 AAFJ01000010_00031 - 0.0012 18.7 1.6 0.0012 18.7 1.6 1.7 2 0 0 2 2 2 1 RhoGAP domain DUF4252 PF14060.6 AAFJ01000010_00031 - 0.32 10.9 8.4 0.086 12.7 4.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4252) ALP_N PF17989.1 AAFJ01000010_00034 - 7.7e-13 48.9 0.1 1.3e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 Actin like proteins N terminal domain FtsA PF14450.6 AAFJ01000010_00034 - 0.00018 21.9 0.2 0.099 13.1 0.0 2.4 2 1 0 2 2 2 2 Cell division protein FtsA DUF4879 PF16219.5 AAFJ01000010_00035 - 0.0012 19.0 0.2 0.0013 18.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4879) YopX PF09643.10 AAFJ01000010_00036 - 3e-12 46.7 2.7 2.3e-11 43.9 1.0 2.2 1 1 1 2 2 2 2 YopX protein DUF4600 PF15372.6 AAFJ01000010_00037 - 0.0093 16.4 0.2 0.011 16.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) TMF_TATA_bd PF12325.8 AAFJ01000010_00037 - 0.023 14.9 0.1 0.035 14.3 0.1 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YopX PF09643.10 AAFJ01000010_00038 - 2.8e-08 33.9 0.6 4e-08 33.4 0.6 1.3 1 1 0 1 1 1 1 YopX protein HTH_17 PF12728.7 AAFJ01000010_00041 - 2.5e-07 30.7 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 AAFJ01000010_00041 - 1.6e-05 24.8 0.0 0.067 13.3 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix HTH_19 PF12844.7 AAFJ01000010_00041 - 6.8e-05 22.8 0.5 0.0032 17.4 0.2 2.7 1 1 1 2 2 2 2 Helix-turn-helix domain MerR PF00376.23 AAFJ01000010_00041 - 0.00015 21.4 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 MerR family regulatory protein HTH_26 PF13443.6 AAFJ01000010_00041 - 0.0011 19.4 0.1 0.26 11.8 0.1 2.6 2 1 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain Phage_CI_repr PF07022.13 AAFJ01000010_00041 - 0.0014 18.7 0.0 0.0073 16.4 0.0 2.0 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain Terminase_5 PF06056.12 AAFJ01000010_00041 - 0.0024 17.7 0.2 0.037 13.9 0.0 2.6 2 1 1 3 3 3 1 Putative ATPase subunit of terminase (gpP-like) HTH_Crp_2 PF13545.6 AAFJ01000010_00041 - 0.0028 17.6 0.0 0.053 13.5 0.0 2.5 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 AAFJ01000010_00041 - 0.0046 16.7 0.0 2.2 8.2 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain MerR_1 PF13411.6 AAFJ01000010_00041 - 0.0086 16.2 0.0 1.1 9.4 0.0 2.6 2 1 0 2 2 2 1 MerR HTH family regulatory protein SL4P PF17618.2 AAFJ01000010_00041 - 0.026 14.6 1.6 4.7 7.3 0.3 2.5 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Vps4_C PF09336.10 AAFJ01000010_00041 - 0.036 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Phage_terminase PF10668.9 AAFJ01000010_00041 - 0.054 13.5 0.1 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Phage terminase small subunit SNase PF00565.17 AAFJ01000010_00042 - 5.7e-24 84.7 0.4 9.2e-24 84.0 0.4 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue O-antigen_lig PF13425.6 AAFJ01000010_00042 - 0.022 13.6 4.2 0.027 13.3 4.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4065 PF13274.6 AAFJ01000010_00043 - 0.001 19.9 0.8 0.0013 19.6 0.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4065) N6_N4_Mtase PF01555.18 AAFJ01000010_00044 - 3.2e-15 56.5 7.5 1.5e-08 34.6 1.9 3.5 3 1 0 3 3 3 2 DNA methylase UPF0020 PF01170.18 AAFJ01000010_00044 - 4.1e-06 26.6 0.0 0.051 13.3 0.0 2.6 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 AAFJ01000010_00044 - 0.0038 16.9 0.0 0.5 10.0 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 AviRa PF11599.8 AAFJ01000010_00044 - 0.021 14.3 0.6 0.12 11.8 0.0 2.3 3 0 0 3 3 3 0 RRNA methyltransferase AviRa Stork_head PF10264.9 AAFJ01000010_00044 - 0.049 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain N6_N4_Mtase PF01555.18 AAFJ01000010_00045 - 9.5e-26 90.9 0.2 2e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Methyltransf_25 PF13649.6 AAFJ01000010_00045 - 2.4e-08 34.6 0.0 1.7e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AAFJ01000010_00045 - 3.1e-08 34.2 0.0 2.9e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 AAFJ01000010_00045 - 6.3e-08 32.5 0.1 1.2e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AAFJ01000010_00045 - 2.1e-06 27.4 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 AAFJ01000010_00045 - 4.7e-05 23.2 0.1 0.0016 18.1 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 AAFJ01000010_00045 - 0.0002 21.0 0.1 0.00089 18.9 0.0 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 AAFJ01000010_00045 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 AAFJ01000010_00045 - 0.0058 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 AAFJ01000010_00045 - 0.024 15.4 0.0 0.068 13.9 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 AAFJ01000010_00045 - 0.027 14.3 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 AAFJ01000010_00045 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1883 PF08980.10 AAFJ01000010_00046 - 0.15 12.0 0.3 0.41 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) ParE_toxin PF05016.15 AAFJ01000010_00047 - 3.8e-09 37.0 0.2 4.7e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 AAFJ01000010_00047 - 0.0008 19.7 0.2 0.00099 19.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ IKKbetaNEMObind PF12179.8 AAFJ01000010_00047 - 0.09 12.8 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain RHH_5 PF07878.11 AAFJ01000010_00048 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 RHH_3 PF12651.7 AAFJ01000010_00048 - 0.00048 20.0 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix domain HicB_lk_antitox PF15919.5 AAFJ01000010_00048 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system CcdA PF07362.12 AAFJ01000010_00048 - 0.025 15.0 0.1 0.034 14.6 0.1 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA PuR_N PF09182.10 AAFJ01000010_00048 - 0.16 11.9 0.1 0.2 11.6 0.1 1.3 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal Bro-N PF02498.17 AAFJ01000010_00049 - 1.6e-22 80.0 2.7 1.9e-22 79.8 0.0 2.2 2 1 0 2 2 2 1 BRO family, N-terminal domain HTH_3 PF01381.22 AAFJ01000010_00049 - 2e-07 31.0 0.1 6.7e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAFJ01000010_00049 - 4.5e-07 29.8 0.1 4.5e-07 29.8 0.1 3.0 4 0 0 4 4 4 1 Helix-turn-helix domain ZapD PF07072.11 AAFJ01000010_00049 - 0.00027 20.7 3.0 0.014 15.2 0.1 2.7 2 1 0 2 2 2 2 Cell division protein HTH_31 PF13560.6 AAFJ01000010_00049 - 0.0048 17.2 0.0 0.0092 16.3 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain SLT PF01464.20 AAFJ01000010_00050 - 3.1e-22 78.4 0.0 3.6e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AAFJ01000010_00050 - 0.017 15.6 0.2 0.035 14.6 0.2 1.6 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Lys PF00062.20 AAFJ01000010_00050 - 0.07 13.4 0.1 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family UPF0146 PF03686.13 AAFJ01000010_00050 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) YafQ_toxin PF15738.5 AAFJ01000010_00052 - 9.3e-26 90.0 0.7 1.1e-25 89.8 0.7 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ASL_C PF08328.11 AAFJ01000010_00052 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DDE_Tnp_1_7 PF13843.6 AAFJ01000010_00053 - 0.0083 15.5 1.0 0.009 15.3 1.0 1.2 1 0 0 1 1 1 1 Transposase IS4 LETM1 PF07766.13 AAFJ01000010_00053 - 0.009 15.4 4.8 0.01 15.2 4.8 1.2 1 0 0 1 1 1 1 LETM1-like protein Baculo_p24 PF05073.12 AAFJ01000010_00053 - 0.035 13.9 2.5 0.038 13.8 2.5 1.0 1 0 0 1 1 1 0 Baculovirus P24 capsid protein PIEZO PF15917.5 AAFJ01000010_00053 - 0.073 12.5 5.7 0.084 12.3 5.7 1.1 1 0 0 1 1 1 0 Piezo DUF4446 PF14584.6 AAFJ01000010_00053 - 1.3 9.0 6.0 1.6 8.7 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Oxidored_q3 PF00499.20 AAFJ01000010_00054 - 0.0036 17.0 0.2 0.0052 16.5 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TctA PF01970.16 AAFJ01000010_00054 - 0.016 14.0 0.6 0.022 13.5 0.6 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Carbpep_Y_N PF05388.11 AAFJ01000010_00054 - 0.027 15.0 2.7 0.027 15.0 0.8 1.8 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Phage_holin_3_6 PF07332.11 AAFJ01000010_00054 - 0.11 12.6 0.3 0.18 11.9 0.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RseC_MucC PF04246.12 AAFJ01000010_00054 - 0.13 12.2 1.3 0.21 11.6 1.3 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 AAFJ01000010_00054 - 0.27 10.0 7.3 0.35 9.6 7.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spore_YhaL PF14147.6 AAFJ01000010_00054 - 4 7.2 5.2 1.7 8.4 0.6 2.5 2 1 0 2 2 2 0 Sporulation protein YhaL Bacillus_PapR PF05968.11 AAFJ01000010_00055 - 0.022 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Bacillus PapR protein YtpI PF14007.6 AAFJ01000010_00055 - 0.024 14.8 9.1 0.038 14.1 0.1 2.9 2 1 1 3 3 3 0 YtpI-like protein TraL PF07178.11 AAFJ01000010_00056 - 3.1e-13 50.0 0.5 3.6e-13 49.8 0.5 1.1 1 0 0 1 1 1 1 TraL protein TraE PF05309.11 AAFJ01000010_00057 - 1e-32 113.0 0.8 1.3e-32 112.7 0.8 1.0 1 0 0 1 1 1 1 TraE protein TraK PF06586.11 AAFJ01000010_00058 - 8.9e-23 81.2 0.2 2.6e-22 79.7 0.2 1.6 1 1 0 1 1 1 1 TraK protein TrbI PF03743.14 AAFJ01000010_00059 - 4.8e-35 121.1 1.5 8e-35 120.4 1.5 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein Cep57_CLD PF14073.6 AAFJ01000010_00059 - 0.0019 18.2 4.7 0.0019 18.2 4.7 2.1 2 1 0 2 2 2 1 Centrosome localisation domain of Cep57 O-antigen_lig PF13425.6 AAFJ01000010_00059 - 0.08 11.7 8.5 0.13 11.0 8.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YrzK PF17449.2 AAFJ01000010_00059 - 0.35 11.2 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized YrzK-like YabA PF06156.13 AAFJ01000010_00059 - 0.61 10.8 11.7 0.061 14.0 5.6 2.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF4481 PF14800.6 AAFJ01000010_00059 - 9 5.7 6.3 1.5 8.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Thioredoxin_2 PF13098.6 AAFJ01000010_00060 - 1.4e-15 57.6 0.2 3.5e-15 56.4 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain DsbC_N PF10411.9 AAFJ01000010_00060 - 8.2e-10 38.0 0.1 1.5e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 AAFJ01000010_00060 - 0.0014 18.8 4.8 0.39 10.9 0.3 2.4 1 1 1 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 AAFJ01000010_00060 - 0.0033 17.6 0.1 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 AAFJ01000010_00060 - 0.086 12.7 0.1 6 6.6 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 AAFJ01000010_00060 - 0.1 12.9 1.3 0.39 11.1 0.7 2.2 2 1 0 2 2 2 0 Thioredoxin-like DUF393 PF04134.12 AAFJ01000010_00060 - 0.14 13.5 0.0 0.33 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF393 SH3_3 PF08239.11 AAFJ01000010_00061 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain TraV PF09676.10 AAFJ01000010_00061 - 0.00078 20.4 1.2 0.00078 20.4 1.2 2.5 2 1 0 2 2 2 1 Type IV conjugative transfer system lipoprotein (TraV) DUF3410 PF11890.8 AAFJ01000010_00061 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) SH3_3 PF08239.11 AAFJ01000010_00062 - 0.00054 20.2 0.1 0.00093 19.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain PBP_dimer PF03717.15 AAFJ01000010_00062 - 0.027 14.8 0.7 0.035 14.4 0.7 1.1 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Closter_coat PF01785.17 AAFJ01000010_00062 - 0.064 12.5 0.2 0.088 12.1 0.2 1.1 1 0 0 1 1 1 0 Closterovirus coat protein TraC_F_IV PF11130.8 AAFJ01000010_00064 - 5.7e-32 111.2 0.0 2.1e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 AAFJ01000010_00064 - 1.6e-10 40.5 0.2 9.3e-10 38.0 0.2 2.0 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 AAFJ01000010_00064 - 5.1e-08 32.2 0.0 0.0045 15.9 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 AAFJ01000010_00064 - 0.0013 19.1 0.4 2.3 8.5 0.0 3.2 2 1 0 3 3 3 2 AAA domain ResIII PF04851.15 AAFJ01000010_00064 - 0.0024 17.9 2.1 0.057 13.4 0.2 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CbiA PF01656.23 AAFJ01000010_00064 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zot PF05707.12 AAFJ01000010_00064 - 0.014 15.1 0.0 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) TraG-D_C PF12696.7 AAFJ01000010_00064 - 0.017 15.1 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG RsgA_GTPase PF03193.16 AAFJ01000010_00064 - 0.056 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF1639 PF07797.14 AAFJ01000010_00064 - 0.073 13.1 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) TrbI_Ftype PF09677.10 AAFJ01000010_00065 - 0.028 14.7 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Peptidase_S26 PF10502.9 AAFJ01000010_00066 - 1.6e-15 57.1 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 PRA-CH PF01502.18 AAFJ01000010_00066 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase TraH PF06122.11 AAFJ01000010_00067 - 5.3e-64 216.8 0.3 5.3e-64 216.8 0.3 1.6 2 0 0 2 2 2 1 Conjugative relaxosome accessory transposon protein ArfGap PF01412.18 AAFJ01000010_00067 - 0.37 10.9 1.7 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf SAYSvFN PF10260.9 AAFJ01000010_00068 - 0.046 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Ribosomal_L6e PF01159.19 AAFJ01000010_00068 - 0.84 10.2 6.1 1.7 9.2 5.5 1.9 1 1 0 1 1 1 0 Ribosomal protein L6e TraN PF06986.11 AAFJ01000010_00069 - 3.3e-26 92.5 26.5 9.2e-25 87.7 20.4 3.0 2 1 0 2 2 2 1 Type-1V conjugative transfer system mating pair stabilisation Lectin_C PF00059.21 AAFJ01000010_00069 - 1.8e-05 25.4 0.0 1.8e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain Xol-1_GHMP-like PF09109.10 AAFJ01000010_00069 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like TraF PF13728.6 AAFJ01000010_00070 - 3.2e-18 66.4 7.8 4.7e-18 65.8 7.8 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein PUA_2 PF14306.6 AAFJ01000010_00070 - 0.015 15.0 0.3 0.028 14.1 0.3 1.6 1 0 0 1 1 1 0 PUA-like domain DUF2369 PF10179.9 AAFJ01000010_00070 - 0.18 12.2 2.7 0.79 10.1 0.3 2.4 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2369) TraG_N PF07916.11 AAFJ01000010_00071 - 3.7e-55 187.6 16.8 3.7e-55 187.6 16.8 1.9 2 1 0 2 2 2 1 TraG-like protein, N-terminal region TIM21 PF08294.11 AAFJ01000010_00072 - 2.7 7.9 3.9 7.5 6.4 0.4 2.5 2 1 1 3 3 3 0 TIM21 YwiC PF14256.6 AAFJ01000010_00072 - 2.9 8.2 13.6 0.14 12.5 1.5 2.9 2 1 1 3 3 3 0 YwiC-like protein T_cell_tran_alt PF15128.6 AAFJ01000010_00072 - 3.6 7.4 10.0 0.69 9.7 2.2 2.8 1 1 2 3 3 3 0 T-cell leukemia translocation-altered Wzy_C PF04932.15 AAFJ01000010_00073 - 0.086 12.5 0.1 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF4713 PF15831.5 AAFJ01000010_00073 - 0.17 12.3 3.6 0.18 12.2 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) PFO_beta_C PF12367.8 AAFJ01000010_00075 - 0.064 13.4 1.6 0.093 12.9 0.2 2.0 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Phage_Treg PF04761.12 AAFJ01000010_00075 - 0.085 13.0 1.7 0.33 11.1 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator AAA_25 PF13481.6 AAFJ01000010_00076 - 1.7e-18 66.9 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 AAFJ01000010_00076 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DnaB_C PF03796.15 AAFJ01000010_00076 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 AAFJ01000010_00076 - 0.041 13.2 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 AAFJ01000010_00076 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 AAFJ01000010_00076 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.15 AAFJ01000010_00076 - 0.23 11.4 2.5 1.2 9.1 2.4 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HTH_3 PF01381.22 AAFJ01000010_00077 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AAFJ01000010_00077 - 1.2e-05 25.2 0.7 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TACC_C PF05010.14 AAFJ01000010_00077 - 0.013 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal T3SchapCesA PF11439.8 AAFJ01000010_00077 - 0.11 12.7 0.4 0.43 10.8 0.1 1.9 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA HTH_31 PF13560.6 AAFJ01000010_00077 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Toprim_3 PF13362.6 AAFJ01000010_00078 - 5.2e-09 36.3 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 AAFJ01000010_00078 - 0.017 15.6 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain AAA_25 PF13481.6 AAFJ01000010_00079 - 1e-15 57.8 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AAFJ01000010_00079 - 0.0004 19.8 0.0 0.0041 16.5 0.0 2.1 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 AAFJ01000010_00079 - 0.0014 18.3 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 AAFJ01000010_00079 - 0.013 14.8 0.0 0.049 13.0 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA PF00004.29 AAFJ01000010_00079 - 0.07 13.6 0.1 0.91 10.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 AAFJ01000010_00079 - 0.34 11.0 3.4 2.6 8.1 3.4 2.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SseC PF04888.12 AAFJ01000010_00080 - 0.0012 18.6 1.4 0.0012 18.6 1.4 1.8 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Leu_Phe_trans PF03588.14 AAFJ01000010_00080 - 0.034 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase T2SSF PF00482.23 AAFJ01000010_00080 - 0.18 11.8 0.1 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3185 PF11381.8 AAFJ01000010_00080 - 0.2 11.7 9.2 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2207 PF09972.9 AAFJ01000010_00080 - 5.6 5.6 16.6 0.074 11.8 0.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Resolvase PF00239.21 AAFJ01000010_00081 - 9.9e-36 123.0 0.2 1.4e-35 122.5 0.2 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain Mga PF05043.13 AAFJ01000010_00081 - 0.012 16.1 2.2 0.15 12.7 0.6 2.5 2 0 0 2 2 2 0 Mga helix-turn-helix domain DUF2790 PF10976.8 AAFJ01000010_00081 - 0.14 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) TrbC PF04956.13 AAFJ01000010_00082 - 4.8e-15 55.6 8.1 5.6e-15 55.4 8.1 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family CagE_TrbE_VirB PF03135.14 AAFJ01000010_00083 - 2.5e-43 148.6 0.5 6.2e-43 147.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 AAFJ01000010_00083 - 1.2e-19 70.3 2.0 2.1e-19 69.5 2.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 AAFJ01000010_00084 - 2.7e-29 101.5 0.0 4.5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) T4SS PF07996.11 AAFJ01000010_00085 - 2.3e-23 83.6 16.9 2.8e-23 83.4 16.9 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins CHASE4 PF05228.13 AAFJ01000010_00085 - 0.05 13.8 5.7 1 9.6 0.2 2.9 2 1 1 3 3 3 0 CHASE4 domain KMP11 PF03037.16 AAFJ01000010_00085 - 0.074 13.8 2.3 0.31 11.8 0.0 2.9 1 1 3 4 4 4 0 Kinetoplastid membrane protein 11 AChE_tetra PF08674.10 AAFJ01000010_00085 - 0.099 12.4 1.2 0.5 10.1 0.1 2.2 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain zf-RING_6 PF14835.6 AAFJ01000010_00085 - 0.12 12.2 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Med8 PF10232.9 AAFJ01000010_00085 - 0.22 11.1 9.0 0.022 14.4 3.9 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PCRF PF03462.18 AAFJ01000010_00085 - 0.25 11.2 11.7 2.7 7.8 0.4 2.2 2 0 0 2 2 2 0 PCRF domain TrbL PF04610.14 AAFJ01000010_00086 - 5.9e-33 114.4 25.5 8.1e-33 114.0 25.5 1.3 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein DUF2070 PF09843.9 AAFJ01000010_00086 - 0.31 9.3 16.7 0.47 8.7 16.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AIM3 PF17096.5 AAFJ01000010_00086 - 5.4 8.0 7.0 9.6 7.2 7.0 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF412 PF04217.13 AAFJ01000010_00086 - 6.5 6.7 10.8 20 5.1 6.7 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF412 VirB8 PF04335.13 AAFJ01000010_00089 - 8.4e-50 169.6 0.1 1e-49 169.3 0.1 1.0 1 0 0 1 1 1 1 VirB8 protein Wzz PF02706.15 AAFJ01000010_00089 - 2.4 8.5 6.7 2.8 8.3 3.2 2.5 2 1 0 2 2 2 0 Chain length determinant protein CagX PF03524.15 AAFJ01000010_00090 - 2.3e-53 181.1 0.8 4.6e-53 180.1 0.8 1.5 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 AAFJ01000010_00091 - 1.3e-46 158.8 0.1 1.3e-46 158.8 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein DUF5345 PF17280.2 AAFJ01000010_00091 - 0.17 11.8 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) MORN_2 PF07661.13 AAFJ01000010_00092 - 0.39 11.1 2.9 2.8 8.4 0.6 2.8 2 0 0 2 2 2 0 MORN repeat variant Ribosomal_S13 PF00416.22 AAFJ01000010_00092 - 0.83 10.1 4.2 17 5.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S13/S18 T2SSE PF00437.20 AAFJ01000010_00093 - 5.1e-54 183.2 0.0 6.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AAFJ01000010_00093 - 4.9e-05 23.6 0.0 9.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAFJ01000010_00093 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AAFJ01000010_00093 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AAFJ01000010_00093 - 0.00062 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 AAFJ01000010_00093 - 0.0028 18.2 1.3 0.0028 18.2 1.3 1.9 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 AAFJ01000010_00093 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 AAFJ01000010_00093 - 0.003 17.0 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_15 PF13175.6 AAFJ01000010_00093 - 0.0035 17.1 2.5 0.0035 17.1 2.5 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 AAFJ01000010_00093 - 0.0041 16.9 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 AAFJ01000010_00093 - 0.0043 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.22 AAFJ01000010_00093 - 0.012 16.0 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 AAFJ01000010_00093 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AAFJ01000010_00093 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 AAFJ01000010_00093 - 0.015 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 AAFJ01000010_00093 - 0.015 15.4 1.0 0.03 14.4 0.2 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 AAFJ01000010_00093 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 AAFJ01000010_00093 - 0.021 14.6 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 AAFJ01000010_00093 - 0.023 14.1 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 AAFJ01000010_00093 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 AAFJ01000010_00093 - 0.045 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 AAFJ01000010_00093 - 0.046 12.6 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 AAFJ01000010_00093 - 0.051 13.6 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.15 AAFJ01000010_00093 - 0.055 13.5 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SMC_N PF02463.19 AAFJ01000010_00093 - 0.063 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 AAFJ01000010_00093 - 0.07 12.9 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 AAFJ01000010_00093 - 0.073 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 AAFJ01000010_00093 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 AAFJ01000010_00093 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 AAFJ01000010_00093 - 0.091 12.8 0.3 0.21 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain GvpD PF07088.11 AAFJ01000010_00093 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 AAFJ01000010_00093 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 AAFJ01000010_00093 - 0.12 12.6 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 AAFJ01000010_00093 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain YscJ_FliF PF01514.17 AAFJ01000010_00094 - 0.019 14.7 2.6 0.31 10.7 0.1 2.4 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Njmu-R1 PF15053.6 AAFJ01000010_00094 - 0.028 13.5 1.6 0.051 12.7 1.6 1.4 1 0 0 1 1 1 0 Mjmu-R1-like protein family FtsQ PF03799.15 AAFJ01000010_00094 - 0.18 12.7 0.8 1.8 9.4 0.0 2.4 3 0 0 3 3 3 0 Cell division protein FtsQ Halogen_Hydrol PF10112.9 AAFJ01000010_00094 - 1.1 9.2 6.9 4.3 7.3 0.8 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Flagellin_N PF00669.20 AAFJ01000010_00094 - 2.1 8.5 7.4 1.9 8.6 0.4 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region SlyX PF04102.12 AAFJ01000010_00094 - 2.2 9.0 7.3 4.6 7.9 0.8 2.6 3 0 0 3 3 2 0 SlyX DUF1664 PF07889.12 AAFJ01000010_00094 - 2.4 8.2 10.7 3.9 7.5 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 AAFJ01000010_00094 - 5.7 7.4 10.3 4 7.9 0.5 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 AAFJ01000010_00094 - 5.9 7.3 7.8 1.6 9.1 0.6 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Vac_Fusion PF02346.16 AAFJ01000010_00094 - 6 6.6 7.8 1.2 8.8 0.8 2.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 FapA PF03961.13 AAFJ01000010_00094 - 6.9 5.2 21.5 0.11 11.0 9.9 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A BST2 PF16716.5 AAFJ01000010_00094 - 6.9 7.3 17.4 1.4 9.6 3.4 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 T4SS-DNA_transf PF02534.14 AAFJ01000010_00095 - 1.3e-109 367.1 0.0 1.8e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AAFJ01000010_00095 - 6.2e-27 94.1 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AAFJ01000010_00095 - 1.4e-18 67.0 0.0 3.3e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain BRI3BP PF14965.6 AAFJ01000010_00095 - 0.22 11.0 2.3 0.26 10.8 1.2 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Cag12 PF13117.6 AAFJ01000010_00096 - 1.1e-16 61.2 0.1 1.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 LPAM_2 PF13627.6 AAFJ01000010_00096 - 0.027 14.3 3.2 0.044 13.6 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF5061 PF16587.5 AAFJ01000010_00096 - 0.15 12.2 0.1 0.19 11.8 0.1 1.3 1 1 0 1 1 1 0 17 kDa common-antigen outer membrane protein TrbM PF07424.11 AAFJ01000010_00097 - 6.3e-39 133.4 1.3 8e-39 133.1 1.3 1.1 1 0 0 1 1 1 1 TrbM Latarcin PF10279.9 AAFJ01000010_00098 - 0.016 15.6 1.6 0.66 10.4 1.6 3.5 1 1 0 1 1 1 0 Latarcin precursor Lipase_GDSL PF00657.22 AAFJ01000010_00098 - 0.033 14.2 1.1 0.067 13.2 0.9 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase T3SS_basalb_I PF17001.5 AAFJ01000010_00098 - 0.078 13.6 4.2 1.7 9.3 0.5 2.8 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cor1 PF04803.12 AAFJ01000010_00098 - 0.15 12.3 22.3 0.15 12.2 6.2 3.3 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1451 PF07295.11 AAFJ01000010_00098 - 0.25 11.3 8.8 0.2 11.7 2.5 2.5 1 1 2 3 3 3 0 Zinc-ribbon containing domain TipAS PF07739.13 AAFJ01000010_00098 - 0.36 11.4 6.4 9 6.9 0.2 3.3 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Exonuc_VII_L PF02601.15 AAFJ01000010_00098 - 0.37 10.3 10.9 0.65 9.5 2.7 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.14 AAFJ01000010_00098 - 2.8 8.3 16.8 3.5 8.0 3.1 2.8 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Topoisom_bac PF01131.20 AAFJ01000010_00100 - 4.4e-96 322.4 2.6 5.6e-96 322.1 2.6 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AAFJ01000010_00100 - 8.4e-12 45.2 0.4 3.4e-11 43.3 0.1 2.3 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 AAFJ01000010_00100 - 1.2e-07 31.3 19.1 0.00081 19.1 3.8 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 AAFJ01000010_00100 - 0.00043 20.5 0.2 0.69 10.2 0.0 2.5 2 0 0 2 2 2 2 zinc-ribbon Zn_ribbon_SprT PF17283.2 AAFJ01000010_00100 - 0.014 15.3 1.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Toprim_2 PF13155.6 AAFJ01000010_00100 - 0.036 14.5 0.3 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 Toprim-like HTH_34 PF13601.6 AAFJ01000010_00100 - 0.074 13.2 0.5 0.77 10.0 0.1 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain Zn-ribbon_8 PF09723.10 AAFJ01000010_00100 - 0.077 13.1 0.7 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 AAFJ01000010_00100 - 0.11 12.4 2.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Toprim_4 PF13662.6 AAFJ01000010_00100 - 0.12 12.8 0.1 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 Toprim domain zf-ribbon_3 PF13248.6 AAFJ01000010_00100 - 0.18 11.3 1.0 12 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 AAFJ01000010_00100 - 0.44 10.7 3.7 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS1 PF03811.13 AAFJ01000010_00100 - 0.46 10.2 3.3 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-HIT PF04438.16 AAFJ01000010_00100 - 0.48 10.3 4.2 5.9 6.8 0.4 2.6 2 0 0 2 2 2 0 HIT zinc finger zf_C2H2_10 PF18414.1 AAFJ01000010_00100 - 2.6 7.7 7.4 11 5.7 1.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger PIN_4 PF13638.6 AAFJ01000010_00100 - 6 7.2 6.6 0.81 10.0 1.0 2.4 3 0 0 3 3 3 0 PIN domain zf-H2C2_2 PF13465.6 AAFJ01000010_00100 - 8.1 7.1 8.1 12 6.5 0.7 3.2 3 0 0 3 3 2 0 Zinc-finger double domain TetR_C_5 PF08360.11 AAFJ01000010_00102 - 0.012 15.8 4.6 0.013 15.7 4.6 1.0 1 0 0 1 1 1 0 QacR-like protein, C-terminal region YopX PF09643.10 AAFJ01000010_00103 - 2.1e-13 50.5 2.2 3.4e-13 49.8 2.2 1.4 1 0 0 1 1 1 1 YopX protein YopX PF09643.10 AAFJ01000010_00104 - 1.7e-05 24.9 0.1 2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 YopX protein TAFII28 PF04719.14 AAFJ01000010_00104 - 0.072 13.2 0.0 5.9 7.1 0.0 2.3 1 1 1 2 2 2 0 hTAFII28-like protein conserved region CRISPR_Cas2 PF09827.9 AAFJ01000010_00106 - 0.00069 19.7 1.5 0.0022 18.1 0.0 2.3 1 1 1 2 2 2 1 CRISPR associated protein Cas2 RRM_1 PF00076.22 AAFJ01000010_00106 - 0.0021 17.8 0.5 0.0083 15.9 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPD11 PF18824.1 AAFJ01000010_00106 - 0.086 12.9 1.8 0.17 12.0 0.4 2.2 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 AAA_31 PF13614.6 AAFJ01000010_00107 - 1.6e-11 44.5 4.7 1.8e-10 41.1 4.7 2.6 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 AAFJ01000010_00107 - 3e-11 43.1 1.8 3.3e-06 26.6 1.0 3.1 1 1 1 2 2 2 2 ATPase MipZ CbiA PF01656.23 AAFJ01000010_00107 - 4.3e-09 36.5 0.1 6.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AAFJ01000010_00107 - 0.00013 21.3 0.3 0.00081 18.7 0.0 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AAFJ01000010_00107 - 0.0012 18.2 0.1 0.91 8.8 0.0 2.1 2 0 0 2 2 2 2 VirC1 protein ABC2_membrane_3 PF12698.7 AAFJ01000010_00107 - 0.0018 17.4 0.8 0.002 17.3 0.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_24 PF13479.6 AAFJ01000010_00107 - 0.0038 17.0 1.2 0.0061 16.3 0.1 1.7 2 1 0 2 2 2 1 AAA domain ParA PF10609.9 AAFJ01000010_00107 - 0.004 16.6 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ATP_bind_1 PF03029.17 AAFJ01000010_00107 - 0.019 14.8 0.1 0.066 13.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF2139 PF09910.9 AAFJ01000010_00107 - 0.14 11.3 0.0 0.45 9.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) CBP_BcsQ PF06564.12 AAFJ01000010_00107 - 0.14 11.6 0.0 0.57 9.6 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_14 PF13173.6 AAFJ01000010_00107 - 0.25 11.4 7.9 0.05 13.6 1.3 2.6 1 1 2 3 3 3 0 AAA domain SNF2_N PF00176.23 AAFJ01000010_00109 - 3.6e-15 55.6 0.1 1.1e-14 53.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AAFJ01000010_00109 - 1.5e-09 38.2 7.1 2.8e-09 37.3 0.0 4.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 AAFJ01000010_00109 - 2.6e-08 34.1 3.3 2.6e-08 34.1 3.3 5.4 5 1 0 6 6 6 1 Type III restriction enzyme, res subunit Eco57I PF07669.11 AAFJ01000010_00109 - 2.1e-06 28.2 1.2 2.6e-05 24.7 0.1 3.7 3 0 0 3 3 3 1 Eco57I restriction-modification methylase DEAD PF00270.29 AAFJ01000010_00109 - 0.00053 19.8 2.9 0.006 16.4 1.4 3.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase MTS PF05175.14 AAFJ01000010_00109 - 0.0033 17.0 0.0 0.015 14.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AAFJ01000010_00109 - 0.056 13.3 0.0 0.25 11.2 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Fic PF02661.18 AAFJ01000010_00112 - 0.025 15.5 0.0 0.055 14.4 0.0 1.6 2 0 0 2 2 2 0 Fic/DOC family Adenyl_cycl_N PF12633.7 AAFJ01000010_00112 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase NT domain CRISPR_Cas2 PF09827.9 AAFJ01000010_00114 - 1e-05 25.6 2.4 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 CRISPR associated protein Cas2 GIT_CC PF16559.5 AAFJ01000010_00114 - 0.014 15.2 5.0 0.023 14.6 5.0 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ABC_tran_Xtn PF12848.7 AAFJ01000010_00114 - 0.014 15.4 2.7 0.024 14.7 2.7 1.4 1 0 0 1 1 1 0 ABC transporter DUF5595 PF18077.1 AAFJ01000010_00114 - 0.039 14.0 3.6 0.08 13.0 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF1722 PF08349.11 AAFJ01000010_00114 - 0.047 14.0 2.6 6.2 7.1 2.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1722) NPBW PF15180.6 AAFJ01000010_00114 - 0.22 11.4 0.6 0.38 10.6 0.6 1.4 1 0 0 1 1 1 0 Neuropeptides B and W EMP24_GP25L PF01105.24 AAFJ01000010_00114 - 0.6 10.0 5.3 0.97 9.3 1.9 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2600 PF10776.9 AAFJ01000010_00115 - 0.0034 16.3 0.5 0.0044 15.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2600) DUF2070 PF09843.9 AAFJ01000010_00115 - 0.0043 15.4 8.7 0.0049 15.2 8.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) COX7a PF02238.15 AAFJ01000010_00115 - 0.0096 16.3 1.7 0.76 10.2 0.1 2.6 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VII HlyIII PF03006.20 AAFJ01000010_00115 - 0.013 15.3 7.6 0.015 15.1 7.6 1.0 1 0 0 1 1 1 0 Haemolysin-III related DUF1129 PF06570.11 AAFJ01000010_00115 - 0.022 14.3 8.0 0.027 13.9 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF1772 PF08592.11 AAFJ01000010_00115 - 0.027 14.8 3.3 0.033 14.5 2.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2663 PF10864.8 AAFJ01000010_00115 - 0.076 13.4 14.4 0.53 10.7 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) DUF898 PF05987.13 AAFJ01000010_00115 - 0.079 12.0 6.5 0.57 9.2 2.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF418 PF04235.12 AAFJ01000010_00115 - 0.12 12.3 2.2 0.24 11.3 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF418) Zip PF02535.22 AAFJ01000010_00115 - 0.18 11.0 6.0 1.2 8.3 6.0 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter Nodulin-like PF06813.13 AAFJ01000010_00115 - 0.21 11.0 7.9 0.077 12.5 3.6 1.8 1 1 1 2 2 2 0 Nodulin-like DUF4293 PF14126.6 AAFJ01000010_00115 - 0.24 11.7 12.1 0.53 10.5 12.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) FixH PF05751.11 AAFJ01000010_00115 - 0.38 10.8 4.2 0.41 10.6 0.3 2.7 3 0 0 3 3 3 0 FixH DUF1673 PF07895.11 AAFJ01000010_00115 - 1.8 8.3 17.6 0.062 13.0 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) GPI2 PF06432.11 AAFJ01000010_00115 - 2.4 7.6 9.8 0.11 11.9 3.3 1.8 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4131 PF13567.6 AAFJ01000010_00115 - 3.4 7.3 5.3 0.85 9.3 1.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Tmpp129 PF10272.9 AAFJ01000010_00115 - 8.7 5.5 9.3 2.5 7.3 5.1 1.8 1 1 1 2 2 2 0 Putative transmembrane protein precursor Relaxase PF03432.14 AAFJ01000010_00116 - 2e-07 30.9 0.8 2e-07 30.9 0.8 3.0 2 1 1 3 3 3 1 Relaxase/Mobilisation nuclease domain Tektin PF03148.14 AAFJ01000010_00116 - 0.19 10.5 6.0 0.13 11.0 0.3 2.4 2 0 0 2 2 2 0 Tektin family RHH_7 PF16777.5 AAFJ01000010_00117 - 0.085 13.3 6.7 0.32 11.4 2.9 2.5 1 1 1 2 2 2 0 Transcriptional regulator, RHH-like, CopG TMEM95 PF15203.6 AAFJ01000010_00117 - 0.58 9.8 2.7 0.45 10.1 0.5 1.8 2 0 0 2 2 2 0 TMEM95 family pRN1_helical PF13010.6 AAFJ01000010_00117 - 4.1 7.4 9.5 2.3 8.2 6.5 1.9 1 1 1 2 2 2 0 Primase helical domain EssA PF10661.9 AAFJ01000010_00118 - 0.2 11.5 8.8 0.18 11.7 7.9 1.3 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA ANAPC4 PF12896.7 AAFJ01000010_00119 - 0.11 11.9 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Fic PF02661.18 AAFJ01000017_00001 - 1.7e-17 64.0 0.1 4.6e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family DUF1495 PF07381.11 AAFJ01000017_00001 - 0.13 12.2 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Toprim_3 PF13362.6 AAFJ01000017_00002 - 5.2e-09 36.3 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 AAFJ01000017_00002 - 0.017 15.6 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain SSB PF00436.25 AAFJ01000017_00005 - 1.4e-29 102.2 0.8 2.1e-29 101.6 0.8 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 AAFJ01000017_00005 - 0.00012 22.0 0.1 0.00017 21.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DD_K PF12121.8 AAFJ01000017_00006 - 6 7.1 6.5 2.6 8.2 2.2 2.1 2 0 0 2 2 2 0 Dermaseptin DUF1640 PF07798.11 AAFJ01000017_00008 - 0.0011 19.0 0.7 0.0014 18.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Merozoite_SPAM PF07133.11 AAFJ01000017_00008 - 0.0095 16.0 4.1 0.012 15.6 4.1 1.1 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) RecT PF03837.14 AAFJ01000017_00009 - 2.3e-36 125.2 0.1 4e-36 124.4 0.0 1.3 1 1 0 1 1 1 1 RecT family GGA_N-GAT PF18308.1 AAFJ01000017_00010 - 0.19 11.4 2.8 0.14 11.8 0.7 1.9 2 0 0 2 2 2 0 GGA N-GAT domain DUF2624 PF11116.8 AAFJ01000017_00015 - 0.041 14.8 0.1 0.084 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DUF4883 PF16224.5 AAFJ01000017_00015 - 0.075 13.3 2.6 0.094 13.0 2.6 1.1 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) DUF2031 PF09592.10 AAFJ01000017_00019 - 0.013 15.0 5.3 0.013 15.1 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) RNA_pol_Rpb2_45 PF10385.9 AAFJ01000017_00019 - 0.1 12.9 0.4 0.13 12.6 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain DUF4830 PF16112.5 AAFJ01000017_00020 - 0.0075 16.7 0.1 0.0094 16.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4830) ParE_toxin PF05016.15 AAFJ01000017_00020 - 0.07 13.7 0.0 0.094 13.3 0.0 1.2 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE PDDEXK_1 PF12705.7 AAFJ01000017_00022 - 1.5e-05 25.0 0.0 2.8e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 AAFJ01000017_00022 - 4.4e-05 23.6 1.4 4.9e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF83 MapZ_C2 PF18708.1 AAFJ01000017_00022 - 0.021 15.1 0.1 0.081 13.2 0.0 2.0 2 0 0 2 2 2 0 MapZ extracellular C-terminal domain 2 NERD PF08378.11 AAFJ01000017_00022 - 0.072 13.6 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 Nuclease-related domain G-gamma PF00631.22 AAFJ01000017_00023 - 0.045 13.8 0.6 0.11 12.5 0.6 1.7 1 0 0 1 1 1 0 GGL domain UPF0449 PF15136.6 AAFJ01000017_00023 - 0.15 12.6 1.7 18 5.9 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 YycI PF09648.10 AAFJ01000017_00024 - 0.011 15.3 0.6 0.011 15.3 0.6 1.1 1 0 0 1 1 1 0 YycH protein Mad3_BUB1_I PF08311.12 AAFJ01000017_00024 - 0.023 14.7 1.0 0.027 14.5 1.0 1.1 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Rsbr_N PF08678.10 AAFJ01000017_00024 - 0.049 13.7 0.1 1.2 9.2 0.0 2.0 1 1 1 2 2 2 0 Rsbr N terminal DUF4450 PF14614.6 AAFL01000016_00001 - 0.0036 16.9 0.7 0.0056 16.3 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4450) VanW PF04294.13 AAFL01000016_00001 - 0.013 15.2 0.3 0.045 13.4 0.1 1.8 1 1 0 2 2 2 0 VanW like protein SBDS PF01172.18 AAFL01000016_00001 - 0.089 12.9 4.1 0.17 12.0 2.2 2.3 1 1 1 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Phage_lysozyme PF00959.19 AAFL01000016_00002 - 1.2e-10 41.7 1.2 2e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Phage lysozyme Vta1 PF04652.16 AAFL01000016_00002 - 2.6 8.0 10.4 0.056 13.4 0.9 2.9 3 1 1 4 4 4 0 Vta1 like SseC PF04888.12 AAFL01000016_00004 - 0.0049 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 AAFL01000016_00004 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 AAFL01000016_00004 - 0.036 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 AAFL01000016_00004 - 0.061 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UvrA_DNA-bind PF17755.1 AAFL01000016_00005 - 0.012 15.9 0.3 5.1 7.5 0.1 2.5 2 0 0 2 2 2 0 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 AAFL01000016_00007 - 0.0051 17.1 0.3 3.2 8.1 0.0 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain Glyco_tranf_2_5 PF13712.6 AAFL01000016_00008 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 AAFL01000016_00009 - 3e-39 135.2 20.8 3e-39 135.2 20.8 3.2 3 1 0 3 3 3 1 TraG-like protein, N-terminal region DUF4131 PF13567.6 AAFL01000016_00010 - 0.0008 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 AAFL01000016_00010 - 0.015 15.2 3.3 0.019 14.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 AAFL01000016_00010 - 0.056 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2663 PF10864.8 AAFL01000016_00010 - 0.13 12.7 2.1 0.16 12.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2721 PF11026.8 AAFL01000016_00010 - 0.27 11.1 5.3 0.34 10.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) YafQ_toxin PF15738.5 AAFL01000016_00011 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 AAFL01000016_00013 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HicB_lk_antitox PF15919.5 AAFL01000016_00015 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 AAFL01000016_00015 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 AAFL01000016_00016 - 1.8e-06 27.9 0.0 3.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, DUF5309 PF17236.2 AAFL01000016_00017 - 3e-05 23.5 0.5 3.3e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5309) SGT1 PF07093.11 AAFL01000016_00019 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 AAFL01000016_00019 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 AAFL01000016_00019 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF4795 PF16043.5 AAFL01000016_00020 - 0.026 14.1 0.1 0.043 13.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3825 PF12873.7 AAFL01000016_00021 - 1.9e-28 99.6 0.3 3e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) GAGBD PF16828.5 AAFL01000016_00022 - 0.011 15.8 1.4 0.012 15.7 1.4 1.0 1 0 0 1 1 1 0 GAG-binding domain on surface antigen IMS_C PF11799.8 AAFL01000016_00025 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AAFL01000016_00025 - 0.0002 21.5 0.0 0.00067 19.8 0.1 1.9 2 0 0 2 2 2 1 IMS family HHH motif AAA_25 PF13481.6 AAFL01000016_00026 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 AAFL01000016_00026 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 AAFL01000016_00026 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 AAFL01000016_00026 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 AAFL01000016_00026 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 AAFL01000016_00026 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 AAFL01000016_00026 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AAFL01000016_00026 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 AAFL01000016_00026 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 AAFL01000016_00026 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 AAFL01000016_00026 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 AAFL01000016_00026 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 AAFL01000016_00026 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AAFL01000016_00026 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 AAFL01000016_00026 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 AAFL01000016_00026 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 AAFL01000016_00026 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobA_MobL PF03389.15 AAFL01000016_00027 - 3.7e-79 265.5 0.0 1.4e-78 263.6 0.0 1.9 2 0 0 2 2 2 1 MobA/MobL family Spectrin PF00435.21 AAFL01000016_00027 - 0.015 15.8 2.4 0.18 12.3 0.2 2.9 2 1 0 2 2 2 0 Spectrin repeat Prominin PF05478.11 AAFL01000016_00027 - 0.02 12.9 1.9 0.029 12.4 1.9 1.2 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.6 AAFL01000016_00027 - 0.021 15.2 2.0 0.059 13.8 0.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF2408 PF10303.9 AAFL01000016_00027 - 0.032 14.8 2.4 0.06 13.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 AAFL01000016_00027 - 0.065 13.5 2.3 6.6 7.1 0.3 3.5 4 0 0 4 4 4 0 Tup N-terminal Mod_r PF07200.13 AAFL01000016_00027 - 0.65 10.1 8.1 0.62 10.2 0.4 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SOAR PF16533.5 AAFL01000016_00027 - 1.2 9.1 5.4 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region DUF4407 PF14362.6 AAFL01000016_00027 - 5.1 6.4 8.4 53 3.0 8.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3847 PF12958.7 AAFL01000016_00028 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 AAFL01000016_00028 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 AAFL01000016_00028 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 AAFL01000016_00028 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CPT PF07931.12 AAFL01000016_00029 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 AAFL01000016_00029 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AAFL01000016_00029 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 AAFL01000016_00029 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 AAFL01000016_00029 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.14 AAFL01000016_00030 - 0.097 11.9 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Ank_3 PF13606.6 AAFL01000019_00001 - 9.9e-11 40.9 0.3 0.002 18.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 AAFL01000019_00001 - 1.5e-08 35.1 0.1 1.1e-07 32.3 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AAFL01000019_00001 - 4.2e-06 27.2 0.1 0.0016 19.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 AAFL01000019_00001 - 0.00044 20.6 0.0 15 6.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 AAFL01000019_00001 - 0.066 13.5 0.0 22 5.5 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 AAFL01000019_00002 - 2.8e-07 30.8 0.0 2.8e-07 30.8 0.0 3.5 3 1 1 4 4 4 1 Restriction endonuclease fold toxin 7 VRR_NUC PF08774.11 AAFL01000019_00002 - 0.027 14.6 0.0 0.093 12.8 0.0 2.0 1 0 0 1 1 1 0 VRR-NUC domain DUF2239 PF09998.9 AAFL01000019_00002 - 3.7 7.3 8.1 1.6 8.5 0.6 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Ank_3 PF13606.6 AAFL01000019_00003 - 1.4e-10 40.5 0.2 0.0029 18.0 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 AAFL01000019_00003 - 8.2e-09 35.9 0.0 5.5e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AAFL01000019_00003 - 1.1e-05 25.9 0.1 0.001 19.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 AAFL01000019_00003 - 5.2e-05 23.5 0.0 1.7 9.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 AAFL01000019_00003 - 0.028 14.8 0.1 1.4 9.4 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Phage_GPD PF05954.11 AAFL01000019_00004 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 AAFL01000019_00004 - 0.01 15.7 1.7 0.029 14.2 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Gp5_C PF06715.12 AAFL01000019_00004 - 0.013 15.6 4.6 0.19 11.9 0.1 4.1 2 1 2 4 4 4 0 Gp5 C-terminal repeat (3 copies) DUF3540 PF12059.8 AAFL01000019_00004 - 0.1 12.4 0.8 0.45 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) TCL1_MTCP1 PF01840.17 AAFL01000019_00004 - 0.11 12.2 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 AAFL01000019_00005 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 AAFL01000019_00006 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 AAFL01000019_00007 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 AAFL01000019_00007 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 AAFL01000019_00007 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 AAFL01000019_00008 - 1e-169 564.9 0.0 1.2e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 AAFL01000019_00008 - 0.096 12.7 0.8 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 AAFL01000019_00009 - 1.2e-51 174.6 3.8 1.3e-51 174.4 3.8 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 AAFL01000019_00009 - 0.082 11.5 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 AAFL01000019_00010 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 AAFL01000019_00010 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 AAFL01000019_00010 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 AAFL01000019_00010 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 AAFL01000019_00011 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 AAFL01000019_00012 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 AAFL01000019_00013 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 AAFL01000019_00014 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 AAFL01000019_00015 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 AAFL01000019_00015 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 AAFL01000019_00015 - 3.5e-26 92.4 2.0 5.3e-26 91.8 2.0 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 AAFL01000019_00015 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 AAFL01000019_00015 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 AAFL01000019_00015 - 0.0036 16.9 5.2 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 AAFL01000019_00015 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DrrA_P4M PF14860.6 AAFL01000019_00015 - 0.4 10.6 5.8 0.11 12.3 1.4 2.4 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain FHA PF00498.26 AAFL01000019_00016 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 AAFL01000019_00016 - 0.0018 18.5 0.0 0.0046 17.3 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 AAFL01000019_00016 - 0.066 13.6 2.7 0.66 10.4 0.7 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain UvrA_DNA-bind PF17755.1 AAFL01000020_00001 - 0.00041 20.7 0.5 0.19 12.1 0.1 2.3 2 0 0 2 2 2 2 UvrA DNA-binding domain Y1_Tnp PF01797.16 AAFL01000020_00004 - 1.9e-13 50.5 2.2 2.3e-13 50.3 2.2 1.1 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 AAFL01000020_00005 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 AAFL01000020_00005 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 AAFL01000020_00005 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 AAFL01000020_00005 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 AAFL01000020_00005 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 AAFL01000020_00005 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 AAFL01000020_00005 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 AAFL01000020_00005 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 AAFL01000020_00005 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 AAFL01000020_00006 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 AAFL01000020_00006 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 AAFL01000020_00007 - 1.9e-13 50.5 2.2 2.3e-13 50.3 2.2 1.1 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 AAFL01000020_00008 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 AAFL01000020_00008 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 AAFL01000020_00008 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 AAFL01000020_00008 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 AAFL01000020_00008 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 AAFL01000020_00008 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 AAFL01000020_00008 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 AAFL01000020_00008 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 AAFL01000020_00008 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3492 PF11997.8 AAFL01000020_00009 - 0.2 11.4 2.9 0.51 10.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CLZ PF16526.5 AAFL01000020_00009 - 1.1 9.7 4.8 11 6.4 0.2 3.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lipase_3 PF01764.25 AAFL01000020_00010 - 2.5e-07 30.7 0.0 8.6e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 AAFL01000020_00010 - 0.00063 19.5 2.0 0.0025 17.6 0.0 2.8 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 AAFL01000020_00010 - 0.084 13.5 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 AAFL01000020_00010 - 0.18 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain CitMHS PF03600.16 AAFL01000020_00011 - 0.022 14.0 0.5 0.025 13.8 0.5 1.1 1 0 0 1 1 1 0 Citrate transporter Ion_trans PF00520.31 AAFL01000020_00011 - 0.88 8.7 13.1 1.3 8.2 13.1 1.4 1 1 0 1 1 1 0 Ion transport protein DUF3810 PF12725.7 AAFL01000020_00011 - 1.1 8.6 11.5 1.3 8.3 11.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Spo7 PF03907.13 AAFL01000020_00011 - 1.9 7.9 6.7 3.1 7.2 6.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DHHC PF01529.20 AAFL01000020_00011 - 9.4 6.3 11.7 18 5.5 11.7 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3810 PF12725.7 AAFL01000020_00013 - 0.0022 17.4 5.2 0.0024 17.3 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) CitMHS PF03600.16 AAFL01000020_00013 - 0.036 13.3 0.3 0.033 13.4 0.3 1.0 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 AAFL01000020_00013 - 0.2 11.4 5.8 0.29 10.8 5.8 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 AAFL01000020_00013 - 2.1 7.7 10.6 4.7 6.6 10.2 1.8 1 1 0 1 1 1 0 Spo7-like protein APH PF01636.23 AAFL01000021_00001 - 3.6e-07 30.4 0.0 3.9e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C15 PF01470.17 AAFL01000021_00002 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 AAFL01000021_00003 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 AAFL01000021_00003 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 AAFL01000021_00003 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 AAFL01000021_00003 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 AAFL01000021_00003 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 AAFL01000021_00003 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_18 PF13238.6 AAFL01000021_00004 - 3.4e-14 53.5 0.0 4.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 AAFL01000021_00004 - 5e-10 39.5 0.0 9.9e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 AAFL01000021_00004 - 1.2e-09 38.5 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AAFL01000021_00004 - 1.5e-08 34.1 0.0 3.2e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 AAFL01000021_00004 - 2.9e-06 27.6 0.1 1.1e-05 25.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 AAFL01000021_00004 - 5.6e-06 26.8 0.0 5.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AAFL01000021_00004 - 2e-05 24.9 0.0 5.9e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 AAFL01000021_00004 - 5.9e-05 23.1 0.0 8.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AAFL01000021_00004 - 0.00012 22.5 0.1 0.00052 20.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AAFL01000021_00004 - 0.00031 21.2 0.0 0.00043 20.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 AAFL01000021_00004 - 0.0012 18.2 0.2 0.0018 17.6 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 AAFL01000021_00004 - 0.0017 18.7 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 AAFL01000021_00004 - 0.0019 17.7 0.0 0.0038 16.7 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 AAFL01000021_00004 - 0.0023 17.7 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AAFL01000021_00004 - 0.0029 18.1 0.1 0.003 18.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 AAFL01000021_00004 - 0.0039 16.9 0.1 0.0042 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AAFL01000021_00004 - 0.004 17.1 0.0 0.049 13.5 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase TIP49 PF06068.13 AAFL01000021_00004 - 0.0061 15.8 0.2 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 AAFL01000021_00004 - 0.0075 15.6 0.7 0.016 14.6 0.1 1.8 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 AAFL01000021_00004 - 0.011 14.8 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 AAFL01000021_00004 - 0.012 15.5 0.5 0.034 14.1 0.2 1.8 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 AAFL01000021_00004 - 0.017 14.9 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 AAFL01000021_00004 - 0.018 14.9 0.1 1 9.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 AAFL01000021_00004 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 AAFL01000021_00004 - 0.022 14.6 0.0 0.069 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 AAFL01000021_00004 - 0.022 14.3 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 RuvB_N PF05496.12 AAFL01000021_00004 - 0.023 14.5 0.1 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MKT1_N PF12247.8 AAFL01000021_00004 - 0.027 14.8 0.0 0.1 13.0 0.0 2.0 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_25 PF13481.6 AAFL01000021_00004 - 0.028 14.0 0.1 0.071 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 AAFL01000021_00004 - 0.039 13.3 0.4 0.084 12.2 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 AAFL01000021_00004 - 0.04 13.1 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Hydin_ADK PF17213.3 AAFL01000021_00004 - 0.041 14.2 1.1 0.054 13.8 0.2 1.6 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 AAFL01000021_00004 - 0.042 13.8 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ArsA_ATPase PF02374.15 AAFL01000021_00004 - 0.047 12.9 0.1 0.099 11.8 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase Rad17 PF03215.15 AAFL01000021_00004 - 0.051 13.5 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 AAFL01000021_00004 - 0.055 13.9 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 AAFL01000021_00004 - 0.056 13.2 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 AAFL01000021_00004 - 0.069 12.7 0.5 0.12 11.9 0.0 1.6 2 1 0 2 2 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 AAFL01000021_00004 - 0.076 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 AAFL01000021_00004 - 0.096 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase3 PF18751.1 AAFL01000021_00004 - 0.14 12.0 0.5 0.4 10.6 0.0 1.9 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_3 PF07726.11 AAFL01000021_00004 - 0.15 11.9 0.1 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PG_binding_3 PF09374.10 AAFL01000021_00004 - 0.18 12.1 0.4 2.2 8.6 0.0 2.5 2 1 1 3 3 2 0 Predicted Peptidoglycan domain Cytidylate_kin2 PF13189.6 AAFL01000021_00004 - 0.29 11.2 2.2 16 5.6 0.2 2.3 1 1 0 2 2 2 0 Cytidylate kinase-like family TnpV PF14198.6 AAFL01000021_00005 - 3.3e-41 139.8 0.5 3.6e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV DUF4368 PF14287.6 AAFL01000021_00006 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 AAFL01000021_00006 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.4 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 AAFL01000021_00006 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 AAFL01000021_00006 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 AAFL01000021_00006 - 0.14 12.2 0.7 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Snapin_Pallidin PF14712.6 AAFL01000021_00006 - 1.2 9.6 6.0 13 6.3 0.2 2.9 3 0 0 3 3 3 0 Snapin/Pallidin IMS PF00817.20 AAFL01000021_00007 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family HTH_3 PF01381.22 AAFL01000021_00009 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 AAFL01000021_00009 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 AAFL01000021_00009 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 AAFL01000021_00009 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AAFL01000021_00009 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 AAFL01000021_00009 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 AAFL01000021_00009 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 AAFL01000021_00009 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 AAFL01000021_00009 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 AAFL01000021_00009 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 AAFL01000021_00009 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 AAFL01000021_00009 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 AAFL01000021_00009 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AAFL01000021_00009 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 AAFL01000021_00009 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 AAFL01000021_00009 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 AAFL01000021_00009 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 AAFL01000021_00009 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 AAFL01000021_00009 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 AAFL01000021_00009 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 AAFL01000021_00011 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 AAFL01000021_00011 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Sigma_reg_N PF13800.6 AAFL01000021_00012 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CCDC-167 PF15188.6 AAFL01000021_00013 - 0.002 18.4 0.4 0.0033 17.7 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 AAFL01000021_00013 - 0.015 15.4 3.5 0.04 14.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) HSBP1 PF06825.12 AAFL01000021_00013 - 0.033 14.0 0.1 2.2 8.2 0.0 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Streptin-Immun PF11083.8 AAFL01000021_00013 - 0.052 14.0 0.6 0.2 12.1 0.1 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4164 PF13747.6 AAFL01000021_00013 - 0.1 12.9 0.4 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Trimer_CC PF08954.11 AAFL01000021_00013 - 0.14 11.7 0.1 9.8 5.8 0.0 3.0 1 1 1 2 2 2 0 Trimerisation motif YafQ_toxin PF15738.5 AAFL01000021_00018 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 AAFL01000021_00018 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 AAFL01000021_00018 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 AAFL01000021_00018 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system WGR PF05406.15 AAFL01000021_00023 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 AAFL01000021_00023 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 AAFL01000021_00024 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 AAFL01000021_00025 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AAFL01000021_00025 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AAFL01000021_00025 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 AAFL01000021_00025 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 AAFL01000021_00025 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 AAFL01000021_00025 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SprT-like PF10263.9 AAFL01000021_00028 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 AAFL01000021_00028 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain DUF4299 PF14132.6 AAFL01000023_00002 - 1.4e-08 34.5 0.1 1.6e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) XPG_I PF00867.18 AAFL01000023_00002 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 AAFL01000023_00004 - 5.8e-17 61.8 2.0 1.1e-16 60.9 2.0 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 AAFL01000023_00004 - 0.25 11.3 7.2 0.13 12.2 1.5 2.3 2 0 0 2 2 2 0 Ribosome recycling factor Imm59 PF15597.6 AAFL01000023_00005 - 0.23 12.0 8.7 0.51 10.9 1.8 2.2 1 1 1 2 2 2 0 Immunity protein 59 CobN-Mg_chel PF02514.16 AAFL01000023_00006 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Ntox24 PF15529.6 AAFL01000023_00007 - 0.00052 20.3 0.6 0.00084 19.6 0.6 1.4 1 1 0 1 1 1 1 Bacterial toxin 24 AHH PF14412.6 AAFL01000023_00011 - 1e-15 57.8 1.5 2e-15 56.9 1.5 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Imm70 PF15601.6 AAFL01000023_00013 - 2.7e-51 172.5 0.6 3e-51 172.4 0.6 1.0 1 0 0 1 1 1 1 Immunity protein 70 Herpes_V23 PF01802.17 AAFL01000023_00013 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein AbfS_sensor PF18225.1 AAFL01000023_00014 - 0.067 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain DUF1574 PF07611.11 AAFL01000023_00015 - 0.023 14.1 2.5 0.027 13.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) LPD7 PF18821.1 AAFL01000023_00015 - 0.037 14.1 0.4 3.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 AAFL01000023_00015 - 1.8 9.1 9.9 1.6 9.2 2.8 3.1 1 1 2 3 3 3 0 Immunity protein 59 TNT PF14021.6 AAFL01000023_00016 - 1.5e-15 57.5 0.0 1.1e-08 35.5 0.0 2.3 2 0 0 2 2 2 2 Tuberculosis necrotizing toxin Ank_3 PF13606.6 AAFL01000023_00019 - 2.9e-10 39.5 0.1 0.00091 19.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 AAFL01000023_00019 - 1.5e-09 38.3 0.0 1.1e-08 35.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AAFL01000023_00019 - 1.3e-05 25.6 0.1 0.0011 19.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 AAFL01000023_00019 - 3.6e-05 24.0 0.0 2.5 8.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 AAFL01000023_00019 - 0.0063 16.8 0.3 0.13 12.7 0.0 3.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Rapsyn_N PF10579.9 AAFL01000025_00002 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region DZR PF12773.7 AAFL01000025_00003 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 AAFL01000025_00003 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 AAFL01000025_00003 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myc-LZ PF02344.15 AAFL01000025_00004 - 0.045 13.9 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Myc leucine zipper domain DivIC PF04977.15 AAFL01000025_00005 - 0.0014 18.3 0.2 0.0014 18.3 0.2 4.2 5 0 0 5 5 5 1 Septum formation initiator Prok-TraM PF09228.10 AAFL01000025_00007 - 0.072 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF2345 PF10106.9 AAFL01000025_00007 - 0.18 11.7 1.5 1.4 8.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Flu_B_M2 PF04772.12 AAFL01000025_00007 - 2.2 8.6 11.0 0.18 12.1 0.4 3.0 1 1 2 3 3 3 0 Influenza B matrix protein 2 (BM2) Y1_Tnp PF01797.16 AAFL01000026_00001 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like PcfJ PF14284.6 AAFL01000026_00002 - 7.7e-06 25.9 1.5 8.6e-06 25.7 1.5 1.1 1 0 0 1 1 1 1 PcfJ-like protein NmrA PF05368.13 AAFL01000026_00002 - 0.0093 15.5 0.3 0.012 15.2 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family DUF4060 PF13269.6 AAFL01000026_00002 - 0.085 12.9 0.1 5.4 7.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4060) GTP_EFTU PF00009.27 AAFL01000026_00004 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AAFL01000026_00004 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AAFL01000026_00004 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AAFL01000026_00004 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AAFL01000026_00004 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AAFL01000026_00004 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AAFL01000026_00004 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 AAFL01000026_00004 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AAFL01000026_00004 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF5442 PF17514.2 AAFL01000026_00005 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) AAA_31 PF13614.6 AAFL01000027_00001 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 AAFL01000027_00001 - 0.0021 18.1 0.8 0.019 15.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 AAFL01000027_00001 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Put_DNA-bind_N PF06971.13 AAFL01000027_00003 - 0.034 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus RseC_MucC PF04246.12 AAFL01000027_00005 - 9.1 6.3 6.3 2.4 8.1 3.1 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2974 PF11187.8 AAFL01000027_00007 - 0.00072 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 AAFL01000027_00007 - 0.044 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 AAFL01000027_00007 - 0.1 12.4 0.2 0.28 11.1 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) DUF2239 PF09998.9 AAFL01000028_00001 - 0.081 12.7 0.7 0.1 12.4 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) sCache_like PF16736.5 AAFL01000028_00001 - 0.11 12.6 5.3 0.16 12.0 5.3 1.2 1 0 0 1 1 1 0 Single Cache-like PepSY_2 PF13670.6 AAFL01000028_00001 - 0.17 11.9 0.9 0.28 11.2 0.9 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ank_3 PF13606.6 AAFL01000028_00002 - 1.1e-09 37.7 0.3 0.013 16.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 AAFL01000028_00002 - 4e-08 33.7 0.1 2.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 AAFL01000028_00002 - 0.00041 20.7 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 AAFL01000028_00002 - 0.0021 18.3 0.1 0.029 14.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 AAFL01000028_00002 - 0.0029 18.2 0.1 0.18 12.4 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 AAFL01000028_00003 - 6.7e-08 32.7 0.0 6.7e-08 32.7 0.0 3.5 3 1 0 3 3 3 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 AAFL01000028_00003 - 2.2 8.1 9.1 1.7 8.4 0.6 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Ank_2 PF12796.7 AAFL01000028_00004 - 4e-12 46.6 0.5 2.9e-07 31.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AAFL01000028_00004 - 1.4e-10 40.4 0.3 0.0017 18.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 AAFL01000028_00004 - 1.4e-05 25.3 0.0 0.76 10.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 AAFL01000028_00004 - 8.4e-05 23.0 0.2 0.018 15.6 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FAM25 PF15825.5 AAFL01000028_00004 - 0.0056 17.0 1.3 2.4 8.6 0.2 2.6 2 0 0 2 2 2 2 FAM25 family Ank_5 PF13857.6 AAFL01000028_00004 - 0.095 13.0 0.1 2.7 8.4 0.0 3.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) AHH PF14412.6 AAFL01000028_00004 - 0.17 11.9 0.6 23 5.1 0.0 2.5 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Tox-REase-7 PF15649.6 AAFL01000028_00005 - 1.3e-08 35.0 0.4 2.4e-08 34.2 0.1 1.6 2 0 0 2 2 2 1 Restriction endonuclease fold toxin 7 Tn7_Tnp_TnsA_N PF08722.11 AAFL01000028_00005 - 0.0021 18.2 1.0 0.0029 17.8 0.1 1.7 2 0 0 2 2 2 1 TnsA endonuclease N terminal VRR_NUC PF08774.11 AAFL01000028_00005 - 0.041 13.9 0.0 0.13 12.4 0.0 1.8 1 1 1 2 2 2 0 VRR-NUC domain adh_short PF00106.25 AAFL01000029_00001 - 0.0094 15.4 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Mur_ligase_C PF02875.21 AAFL01000029_00001 - 0.086 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 AAFL01000029_00002 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 AAFL01000029_00002 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal PTS-HPr PF00381.19 AAFL01000029_00003 - 0.17 12.1 0.0 0.19 12.0 0.0 1.0 1 0 0 1 1 1 0 PTS HPr component phosphorylation site NYN PF01936.18 AAFL01000029_00005 - 1.2e-09 38.8 0.0 1.4e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 AAFL01000029_00005 - 0.014 15.3 0.5 0.028 14.3 0.5 1.6 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family PIN7 PF18475.1 AAFL01000029_00005 - 0.028 15.1 0.0 0.045 14.4 0.0 1.4 1 0 0 1 1 1 0 PIN domain DUF2400 PF09674.10 AAFL01000029_00006 - 0.26 11.2 4.0 0.56 10.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) HTH_46 PF15977.5 AAFL01000030_00002 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 AAFL01000030_00002 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 AAFL01000030_00002 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 AAFL01000030_00002 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 AAFL01000030_00002 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 AAFL01000030_00003 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 AAFL01000030_00003 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 AAFL01000030_00003 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide AAA_25 PF13481.6 AAFL01000031_00001 - 4.4e-15 55.8 0.0 1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AAFL01000031_00001 - 0.00028 20.3 0.0 0.0018 17.6 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 AAFL01000031_00001 - 0.0021 17.8 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 AAFL01000031_00001 - 0.007 15.7 0.0 0.07 12.5 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 AAFL01000031_00001 - 0.02 15.3 0.3 0.31 11.5 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ApoC-I PF04691.12 AAFL01000031_00001 - 0.13 12.2 3.2 4.8 7.2 0.0 3.9 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) CbiA PF01656.23 AAFL01000031_00001 - 0.21 11.6 2.1 0.89 9.6 2.1 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 AAFL01000031_00001 - 0.65 9.6 5.5 13 5.5 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain DUF1947 PF09183.10 AAFL01000031_00001 - 0.65 10.3 6.4 1.6 9.1 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) HicA_toxin PF07927.12 AAFL01000031_00002 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Endomucin PF07010.12 AAFL01000032_00002 - 0.029 14.4 0.5 0.03 14.3 0.5 1.1 1 0 0 1 1 1 0 Endomucin HicA_toxin PF07927.12 AAFL01000032_00003 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, N-glycanase_N PF09112.10 AAFL01000033_00001 - 0.016 15.0 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Phage_terminase PF10668.9 AAFL01000033_00001 - 0.17 11.9 0.6 0.37 10.9 0.6 1.4 1 0 0 1 1 1 0 Phage terminase small subunit RHH_7 PF16777.5 AAFL01000033_00002 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 AAFL01000033_00002 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal adh_short PF00106.25 AAFL01000033_00003 - 0.0094 15.4 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Mur_ligase_C PF02875.21 AAFL01000033_00003 - 0.086 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain HicB_lk_antitox PF15919.5 AAFL01000034_00001 - 4.4e-08 33.3 0.0 6.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Toprim_3 PF13362.6 AAFL01000035_00001 - 1.3e-06 28.7 0.1 4.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 AAFL01000035_00001 - 0.0086 16.3 0.1 0.88 9.9 0.0 2.3 2 0 0 2 2 2 2 Retrotransposon gag protein Acetyltransf_7 PF13508.7 AANQ01000006_00002 - 0.0008 19.8 0.1 0.002 18.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AANQ01000006_00002 - 0.021 15.1 0.1 0.051 13.8 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GramPos_pilinBB PF16569.5 AANQ01000006_00002 - 0.2 12.5 4.3 0.17 12.7 1.7 2.0 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain Relaxase PF03432.14 AANQ01000006_00003 - 3.6e-10 39.9 7.4 3.6e-10 39.9 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 AANQ01000006_00004 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 AANQ01000006_00004 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 AANQ01000006_00004 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 AANQ01000006_00004 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 AANQ01000006_00004 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 AANQ01000006_00005 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 AANQ01000006_00005 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 AANQ01000006_00005 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 AANQ01000006_00007 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 AANQ01000006_00007 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 AANQ01000006_00007 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 AANQ01000006_00007 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 AANQ01000006_00008 - 0.0069 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 AANQ01000006_00009 - 0.0079 16.2 2.8 0.01 15.8 2.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 AANQ01000006_00009 - 1.1 9.3 4.2 2 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 AANQ01000006_00011 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 AANQ01000006_00012 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 AANQ01000006_00013 - 1.6e-14 54.0 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AANQ01000006_00013 - 0.00038 19.9 0.0 0.0019 17.6 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 AANQ01000006_00013 - 0.0022 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 AANQ01000006_00013 - 0.009 15.4 0.0 0.058 12.7 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 AANQ01000006_00013 - 0.0093 16.4 0.2 0.22 11.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 AANQ01000006_00013 - 0.18 11.9 1.8 0.82 9.7 1.8 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 AANQ01000006_00013 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 AANQ01000006_00014 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 AANQ01000006_00014 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 AANQ01000006_00014 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 AANQ01000006_00014 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 AANQ01000006_00015 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 AANQ01000006_00017 - 2.7e-15 56.4 6.5 2.8e-15 56.3 6.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 AANQ01000006_00017 - 0.071 13.0 4.3 0.096 12.5 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 AANQ01000006_00018 - 2.4e-51 174.8 0.3 5.5e-51 173.6 0.3 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 AANQ01000006_00018 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 AANQ01000006_00018 - 0.046 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 AANQ01000006_00019 - 1.8e-31 108.5 0.0 2.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Y_Y_Y PF07495.13 AANQ01000006_00019 - 0.1 12.6 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PBECR2 PF18810.1 AANQ01000006_00020 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 AANQ01000006_00021 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 AANQ01000006_00022 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 AANQ01000006_00022 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 AANQ01000006_00022 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 AANQ01000006_00022 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 AANQ01000006_00023 - 1e-28 101.1 13.2 1.4e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 AANQ01000006_00023 - 0.0036 17.4 0.6 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 AANQ01000006_00023 - 0.015 15.9 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain KMP11 PF03037.16 AANQ01000006_00023 - 0.026 15.3 1.5 0.17 12.7 0.0 3.1 2 2 0 2 2 2 0 Kinetoplastid membrane protein 11 Tissue_fac PF01108.17 AANQ01000006_00023 - 0.03 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Tissue factor AATF-Che1 PF13339.6 AANQ01000006_00023 - 0.34 11.6 11.8 0.41 11.3 4.5 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 AANQ01000006_00024 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 AANQ01000006_00024 - 0.061 13.1 0.9 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 AANQ01000006_00024 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Trep_dent_lipo PF09710.10 AANQ01000006_00025 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 AANQ01000006_00025 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 AANQ01000006_00025 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 AANQ01000006_00026 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 AANQ01000006_00026 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 AANQ01000006_00027 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 AANQ01000006_00027 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 AANQ01000006_00027 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 AANQ01000006_00028 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 AANQ01000006_00028 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 AANQ01000006_00029 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AANQ01000006_00029 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AANQ01000006_00029 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AANQ01000006_00029 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 AANQ01000006_00029 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AANQ01000006_00029 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 AANQ01000006_00029 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AANQ01000006_00029 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 AANQ01000006_00029 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 AANQ01000006_00029 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 AANQ01000006_00029 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 AANQ01000006_00029 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 AANQ01000006_00029 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AANQ01000006_00029 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 AANQ01000006_00029 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 AANQ01000006_00029 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AANQ01000006_00029 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 AANQ01000006_00029 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 AANQ01000006_00029 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 AANQ01000006_00029 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AANQ01000006_00029 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 AANQ01000006_00029 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 AANQ01000006_00029 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 AANQ01000006_00029 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 AANQ01000006_00029 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 AANQ01000006_00029 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 AANQ01000006_00029 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 AANQ01000006_00029 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 AANQ01000006_00029 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 AANQ01000006_00029 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AANQ01000006_00029 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AANQ01000006_00029 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 AANQ01000006_00030 - 1.4e-105 353.8 0.1 1.9e-105 353.4 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AANQ01000006_00030 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AANQ01000006_00030 - 6.2e-16 58.3 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 AANQ01000006_00031 - 1e-16 61.2 0.1 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 AANQ01000006_00031 - 0.062 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 AANQ01000006_00032 - 9.5e-39 132.8 1.2 1.2e-38 132.5 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 AANQ01000006_00033 - 0.02 14.7 1.4 0.033 14.0 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 AANQ01000006_00033 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family TACC_C PF05010.14 AANQ01000006_00033 - 2.1 8.1 10.2 3.7 7.3 8.3 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 AANQ01000006_00033 - 4.9 7.3 12.2 4.4 7.4 3.2 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IFT20 PF14931.6 AANQ01000006_00033 - 5.9 7.1 10.6 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 KH_5 PF13184.6 AANQ01000006_00034 - 0.003 17.6 0.2 0.0034 17.4 0.2 1.0 1 0 0 1 1 1 1 NusA-like KH domain DUF5526 PF17664.1 AANQ01000006_00034 - 0.027 14.0 0.2 0.029 13.9 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5526) Redoxin PF08534.10 AANQ01000006_00035 - 0.029 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 AANQ01000006_00035 - 0.12 12.6 0.1 0.12 12.6 0.1 2.5 2 1 1 3 3 3 0 Uncharacterized YnfE-like Topoisom_bac PF01131.20 AANQ01000006_00036 - 3.2e-97 326.1 8.5 4.5e-97 325.7 8.5 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AANQ01000006_00036 - 4.4e-12 46.1 2.4 7.3e-12 45.4 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 AANQ01000006_00036 - 5.7e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 AANQ01000006_00036 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 AANQ01000006_00036 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 AANQ01000006_00036 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 AANQ01000006_00036 - 0.038 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 AANQ01000006_00036 - 0.052 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair zf-C2H2_4 PF13894.6 AANQ01000006_00036 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 AANQ01000006_00036 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 AANQ01000006_00036 - 0.09 13.0 4.5 1 9.6 3.7 2.5 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 AANQ01000006_00036 - 0.43 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 AANQ01000006_00036 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 AANQ01000006_00036 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 AANQ01000006_00036 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 AANQ01000006_00036 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 AANQ01000006_00036 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 AANQ01000006_00037 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 AANQ01000006_00037 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 AANQ01000006_00039 - 1.2e-59 201.1 0.3 1.7e-59 200.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AANQ01000006_00039 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AANQ01000006_00039 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AANQ01000006_00039 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AANQ01000006_00039 - 9.9e-07 28.8 0.1 2.3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AANQ01000006_00039 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AANQ01000006_00039 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 AANQ01000006_00039 - 0.02 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AANQ01000006_00039 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 AANQ01000006_00039 - 0.11 12.0 0.2 0.45 10.0 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Papo_T_antigen PF02380.15 AANQ01000006_00040 - 0.00028 21.0 1.6 0.00035 20.7 1.6 1.4 1 0 0 1 1 1 1 T-antigen specific domain CEBP_ZZ PF16366.5 AANQ01000006_00040 - 0.022 15.0 2.6 0.03 14.6 2.6 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1272 PF06906.11 AANQ01000006_00040 - 0.049 13.7 3.8 0.074 13.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 AANQ01000006_00041 - 2.9e-05 24.1 0.4 0.00063 19.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 AANQ01000006_00041 - 0.00046 20.3 0.8 0.0047 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 AANQ01000006_00041 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 AANQ01000006_00041 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 AANQ01000006_00042 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 AANQ01000006_00042 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal PDDEXK_9 PF08011.11 AANQ01000006_00043 - 0.017 15.0 0.2 0.032 14.1 0.2 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF5445 PF17520.2 AANQ01000006_00044 - 1 9.2 12.2 1.3 8.9 11.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5445) Adenyl_transf PF04439.12 AJ489618_00001 - 6.7e-81 271.5 0.9 7.6e-81 271.3 0.9 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 AJ489618_00002 - 7.8e-21 74.5 0.1 1e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AJ489618_00002 - 1.4e-13 51.1 0.1 2.4e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AJ489618_00002 - 2.6e-12 46.8 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AJ489618_00002 - 3e-10 40.5 1.6 3.6e-10 40.2 1.6 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AJ489618_00002 - 0.00021 21.4 0.0 0.0004 20.4 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 AJ489618_00002 - 0.00052 20.7 0.0 0.00064 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AJ489618_00002 - 0.0019 18.3 0.0 0.0078 16.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AJ489618_00002 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 AJ489618_00002 - 0.035 13.6 0.2 0.11 12.0 0.2 1.8 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_8 PF13523.6 AJ489618_00002 - 0.042 13.5 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 AJ489618_00002 - 0.08 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ APH PF01636.23 AJ489618_00003 - 4.5e-26 92.2 0.0 5.2e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AJ489618_00003 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 AJ489618_00003 - 0.0099 15.5 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family HTH_11 PF08279.12 AJ489618_00004 - 0.00042 20.2 0.1 0.00056 19.8 0.1 1.2 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AJ489618_00004 - 0.096 12.3 0.3 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Resolvase PF00239.21 AJ490186_00001 - 4.3e-18 65.8 0.3 7.1e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain MerR PF00376.23 AJ490186_00001 - 1.5e-12 47.1 0.0 2.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 AJ490186_00001 - 6e-11 42.3 0.0 1.7e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 MerR HTH family regulatory protein HTH_17 PF12728.7 AJ490186_00001 - 0.00043 20.4 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain NTPase_P4 PF11602.8 AJ490186_00001 - 0.0027 17.0 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 ATPase P4 of dsRNA bacteriophage phi-12 PIN_2 PF10130.9 AJ490186_00001 - 0.063 13.5 1.4 0.083 13.1 0.4 1.6 2 0 0 2 2 2 0 PIN domain HTH_23 PF13384.6 AJ490186_00001 - 0.068 13.0 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain OrfB_Zn_ribbon PF07282.11 AJ490186_00002 - 2.1e-22 78.8 0.9 4.2e-22 77.8 0.9 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 AJ490186_00002 - 2.7e-18 66.4 4.5 2.8e-18 66.3 2.3 2.1 2 1 0 2 2 2 1 Probable transposase HTH_OrfB_IS605 PF12323.8 AJ490186_00002 - 7.7e-15 54.1 0.3 2.2e-14 52.6 0.3 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Zn_Tnp_IS1595 PF12760.7 AJ490186_00002 - 0.036 14.0 2.2 0.071 13.1 2.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain APH PF01636.23 AJ490186_00003 - 5.9e-26 91.8 0.0 6.9e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AJ490186_00003 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 AJ490186_00003 - 0.018 14.7 0.0 3 7.4 0.0 2.2 1 1 0 2 2 2 0 RIO1 family PRELI PF04707.14 AVFM02000066_00001 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 AVFM02000066_00001 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 AVFM02000066_00001 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Relaxase PF03432.14 AVFM02000068_00001 - 2.8e-10 40.2 7.9 2.8e-10 40.2 7.9 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain AdenylateSensor PF16579.5 AVFM02000068_00001 - 0.15 12.5 7.3 3.7 8.0 0.5 3.3 2 1 0 3 3 3 0 Adenylate sensor of SNF1-like protein kinase Endostatin PF06482.11 AVFM02000068_00001 - 1.1 8.6 7.0 0.2 11.1 3.1 1.7 1 1 1 2 2 2 0 Collagenase NC10 and Endostatin Helicase_C PF00271.31 AVFM02000069_00001 - 0.0015 18.9 0.0 0.0015 18.9 0.0 3.0 3 1 1 4 4 4 1 Helicase conserved C-terminal domain efb-c PF12199.8 AVFM02000069_00002 - 0.05 13.7 0.3 0.07 13.2 0.3 1.3 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Toprim PF01751.22 AVFM02000070_00001 - 3.2e-13 49.8 0.0 4.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Toprim domain Topoisom_bac PF01131.20 AVFM02000070_00001 - 0.008 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase EF-hand_8 PF13833.6 AVFM02000070_00001 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair SNF2_N PF00176.23 AVFM02000073_00001 - 1.2e-10 40.6 0.2 3.1e-10 39.3 0.2 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 AVFM02000073_00001 - 6.1e-10 39.4 9.3 1.8e-08 34.5 9.2 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AVFM02000073_00001 - 5.8e-07 29.4 0.4 0.0003 20.6 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_11 PF13086.6 AVFM02000073_00001 - 0.0032 17.3 4.6 1 9.1 3.0 2.3 1 1 1 2 2 2 2 AAA domain Tup_N PF08581.10 AVFM02000073_00001 - 0.072 13.4 0.3 0.072 13.4 0.3 4.0 4 1 0 4 4 4 0 Tup N-terminal CLZ PF16526.5 AVFM02000073_00001 - 1.5 9.3 4.7 2.5 8.5 1.4 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1690 PF07956.11 AVFM02000073_00001 - 1.8 9.0 6.3 2 8.9 0.6 2.7 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Eco57I PF07669.11 AVFM02000073_00002 - 1.3e-05 25.6 0.2 5.2e-05 23.7 0.2 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 AVFM02000073_00002 - 0.0038 16.8 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 AVFM02000073_00003 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 AVFM02000073_00003 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Cag12 PF13117.6 AVFM02000074_00002 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 AVFM02000074_00002 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 AVFM02000074_00002 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 AVFM02000074_00002 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 AVFM02000074_00003 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AVFM02000074_00003 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AVFM02000074_00003 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 AVFM02000074_00003 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 AVFM02000074_00004 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AVFM02000074_00004 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AVFM02000074_00004 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AVFM02000074_00004 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 AVFM02000074_00004 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AVFM02000074_00004 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AVFM02000074_00004 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 AVFM02000074_00004 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 AVFM02000074_00004 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 AVFM02000074_00004 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 AVFM02000074_00004 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 AVFM02000074_00004 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 AVFM02000074_00004 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 AVFM02000074_00004 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 AVFM02000074_00004 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 AVFM02000074_00004 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 AVFM02000074_00004 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 AVFM02000074_00004 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 AVFM02000074_00004 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 AVFM02000074_00004 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 AVFM02000074_00004 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AVFM02000074_00004 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 AVFM02000074_00004 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 AVFM02000074_00004 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 AVFM02000074_00004 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 AVFM02000074_00004 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 AVFM02000074_00004 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 AVFM02000074_00004 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 AVFM02000074_00004 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AVFM02000074_00004 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AVFM02000074_00004 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 AVFM02000074_00005 - 1.9e-48 164.8 0.1 3.2e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 AVFM02000074_00005 - 0.022 13.8 0.1 0.032 13.3 0.1 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease HNOBA PF07701.14 AVFM02000075_00001 - 0.077 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 AVFM02000075_00001 - 0.081 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like bZIP_1 PF00170.21 AVFM02000075_00001 - 0.79 9.9 4.9 6.3 7.0 0.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor Phage_pRha PF09669.10 AVFM02000075_00002 - 1.5e-28 99.2 0.0 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 AVFM02000075_00002 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 AVFM02000075_00003 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 AVFM02000075_00003 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 AVFM02000075_00003 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 AVFM02000075_00003 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 AVFM02000075_00003 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 AVFM02000075_00003 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 AVFM02000075_00004 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 AVFM02000075_00005 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 AVFM02000075_00005 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 AVFM02000075_00005 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 AVFM02000075_00005 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 AVFM02000075_00006 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 AVFM02000075_00006 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 AVFM02000075_00006 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 AVFM02000075_00006 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 AVFM02000075_00006 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 AVFM02000075_00006 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 AVFM02000075_00007 - 2.7e-29 102.5 30.5 2.7e-29 102.5 30.5 1.5 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 AVFM02000075_00007 - 0.21 11.4 1.5 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 AVFM02000075_00008 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 AVFM02000075_00008 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 AVFM02000075_00009 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 AVFM02000075_00009 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 AVFM02000075_00010 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 AVFM02000075_00010 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) SSB PF00436.25 AVFM02000076_00001 - 1.3e-23 83.0 0.0 1.7e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DnaJ-X PF14308.6 AVFM02000076_00001 - 0.0027 17.2 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 X-domain of DnaJ-containing Colicin_Ia PF11504.8 AVFM02000076_00001 - 0.11 12.7 0.1 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Colicin Ia DUF1981 PF09324.10 AVFM02000076_00001 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) DUF4389 PF14333.6 AVFM02000076_00002 - 0.054 13.4 3.8 0.08 12.9 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4389) DUF2512 PF10710.9 AVFM02000076_00002 - 0.12 12.1 6.0 0.13 11.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) TctB PF07331.11 AVFM02000076_00002 - 0.53 10.6 9.7 0.56 10.5 9.7 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family LptF_LptG PF03739.14 AVFM02000076_00002 - 7.6 5.3 10.9 8.3 5.1 10.9 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1129 PF06570.11 AVFM02000076_00002 - 7.9 5.9 8.5 9 5.7 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4407 PF14362.6 AVFM02000076_00002 - 8.6 5.6 8.5 10 5.4 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MgtE_N PF03448.17 AVFM02000077_00001 - 4e-05 24.2 0.3 0.039 14.6 0.3 2.1 1 1 1 2 2 2 2 MgtE intracellular N domain Com_YlbF PF06133.11 AVFM02000077_00001 - 0.0099 16.5 1.9 0.0099 16.5 1.9 1.5 2 0 0 2 2 2 1 Control of competence regulator ComK, YlbF/YmcA CpXC PF14353.6 AVFM02000077_00002 - 0.033 14.2 2.2 0.041 13.9 2.2 1.3 1 1 0 1 1 1 0 CpXC protein A2L_zn_ribbon PF08792.10 AVFM02000077_00002 - 0.71 9.7 5.5 2.7 7.8 0.6 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain T4SS PF07996.11 AVFM02000078_00001 - 3.4e-07 30.9 8.7 3.4e-07 30.9 8.7 2.4 1 1 1 2 2 2 1 Type IV secretion system proteins HBM PF16591.5 AVFM02000078_00001 - 0.0086 15.5 15.0 0.015 14.7 0.2 2.3 2 0 0 2 2 2 1 Helical bimodular sensor domain HTH_16 PF12645.7 AVFM02000078_00001 - 0.053 13.6 0.4 0.79 9.8 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain NYD-SP28_assoc PF14775.6 AVFM02000078_00001 - 0.14 12.2 5.9 0.84 9.8 0.5 3.5 2 1 1 3 3 3 0 Sperm tail C-terminal domain GCN5L1 PF06320.13 AVFM02000078_00001 - 0.48 10.6 0.1 0.48 10.6 0.1 3.4 2 1 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF2937 PF11157.8 AVFM02000078_00001 - 4.9 6.9 8.7 14 5.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) FlxA PF14282.6 AVFM02000078_00001 - 7.4 6.6 29.5 5.1 7.1 4.7 4.3 2 1 2 4 4 4 0 FlxA-like protein FIVAR PF07554.13 AVFM02000078_00002 - 0.034 14.9 8.8 0.056 14.2 8.8 1.3 1 1 0 1 1 1 0 FIVAR domain PRD PF00874.20 AVFM02000078_00002 - 0.077 13.3 4.1 0.096 13.0 4.1 1.1 1 0 0 1 1 1 0 PRD domain T4SS-DNA_transf PF02534.14 AVFM02000079_00001 - 3e-58 197.8 2.6 1.2e-57 195.8 2.6 1.7 1 1 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TrwB_AAD_bind PF10412.9 AVFM02000079_00001 - 4.2e-19 68.7 0.0 2.4e-14 53.1 0.0 2.1 1 1 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 AVFM02000079_00001 - 3e-14 53.1 0.0 2.4e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 TraM recognition site of TraD and TraG DUF418 PF04235.12 AVFM02000079_00001 - 0.057 13.4 1.4 0.091 12.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF418) VirB8 PF04335.13 AVFM02000080_00001 - 3.6e-29 102.1 0.9 4.2e-29 101.9 0.9 1.0 1 0 0 1 1 1 1 VirB8 protein TrwB_AAD_bind PF10412.9 AVFM02000080_00003 - 6.4e-05 22.0 0.0 7.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain CNTF PF01110.17 AVFM02000080_00003 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor YsaB PF13983.6 AVFM02000081_00001 - 0.11 12.8 0.1 0.42 10.9 0.2 1.8 2 0 0 2 2 2 0 YsaB-like lipoprotein CagX PF03524.15 AVFM02000082_00001 - 9.1e-26 90.9 0.7 1e-25 90.7 0.7 1.0 1 0 0 1 1 1 1 Conjugal transfer protein DUF4905 PF16248.5 AVFM02000082_00001 - 0.055 13.4 0.1 0.2 11.6 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) Phosphodiest PF01663.22 AVFM02000082_00001 - 0.076 12.6 1.3 0.25 10.9 1.1 1.7 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase ETRAMP PF09716.10 AVFM02000082_00002 - 1.5 9.0 8.9 0.36 10.9 1.5 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TrbI PF03743.14 AVFM02000082_00003 - 8.1e-32 110.6 0.7 1.1e-31 110.2 0.7 1.1 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein TrbI PF03743.14 AVFM02000082_00004 - 1.8e-06 27.9 0.1 1.9e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein TraH_2 PF06871.11 AVFM02000082_00004 - 0.06 13.0 0.2 5.2 6.6 0.0 1.9 1 1 1 2 2 2 0 TraH_2 FOXP-CC PF16159.5 AVFM02000082_00005 - 0.0033 18.0 0.3 0.0038 17.8 0.3 1.2 1 0 0 1 1 1 1 FOXP coiled-coil domain MCR_C PF04609.12 AVFM02000082_00005 - 0.23 10.5 4.5 0.25 10.4 4.5 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Allexi_40kDa PF05549.11 AVFM02000082_00005 - 0.66 9.4 4.9 0.64 9.5 4.9 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Aida_N PF08910.10 AVFM02000082_00005 - 0.68 10.4 5.2 0.71 10.3 5.2 1.1 1 0 0 1 1 1 0 Aida N-terminus TrbL PF04610.14 AVFM02000084_00002 - 1.5e-31 109.9 22.6 1.5e-31 109.9 22.6 2.2 3 0 0 3 3 3 1 TrbL/VirB6 plasmid conjugal transfer protein Topoisom_bac PF01131.20 AVFM02000084_00003 - 2.2e-13 50.0 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AVFM02000084_00003 - 4.4e-10 39.7 0.3 9.2e-10 38.7 0.2 1.5 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 AVFM02000084_00003 - 0.1 13.1 0.0 0.29 11.6 0.0 1.8 2 1 0 2 2 2 0 Toprim domain DUF2852 PF11014.8 AVFM02000085_00002 - 0.0052 16.9 1.5 0.0052 16.9 1.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2852) DUF5442 PF17514.2 AVFM02000085_00002 - 0.026 14.7 5.3 0.026 14.7 5.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Stn1_C PF12659.7 AVFM02000085_00002 - 0.1 12.6 3.0 0.25 11.3 3.0 1.8 1 1 0 1 1 1 0 Telomere capping C-terminal wHTH DUF1856 PF08983.10 AVFM02000085_00002 - 0.53 10.6 4.2 7.3 6.9 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1856) NifT PF06988.11 AVFM02000085_00002 - 7.3 6.5 6.9 3.1 7.6 0.3 3.0 2 1 1 3 3 3 0 NifT/FixU protein Toprim_2 PF13155.6 AVFM02000085_00004 - 2.6e-13 50.2 0.9 2e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 AVFM02000085_00004 - 0.00012 22.3 0.1 0.00032 21.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3991) Sushi_2 PF09014.10 AVFM02000085_00004 - 0.056 13.3 0.6 0.091 12.7 0.1 1.6 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Toprim_3 PF13362.6 AVFM02000085_00004 - 0.067 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Toprim domain Toprim_4 PF13662.6 AVFM02000085_00004 - 0.071 13.6 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 Toprim domain Toprim PF01751.22 AVFM02000085_00004 - 0.09 13.0 1.2 0.15 12.3 0.5 1.7 1 1 1 2 2 2 0 Toprim domain Osmo_CC PF08946.10 AVFM02000085_00004 - 0.26 11.6 0.1 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Cys_rich_KTR PF14205.6 AVFM020000_00001 - 4.7e-32 109.6 5.1 5.2e-32 109.4 5.1 1.0 1 0 0 1 1 1 1 Cysteine-rich KTR Prim_Zn_Ribbon PF08273.12 AVFM020000_00001 - 0.00057 20.1 1.3 0.0023 18.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding domain of primase-helicase zf-ISL3 PF14690.6 AVFM020000_00001 - 0.0029 18.2 0.6 0.78 10.5 0.1 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 AVFM020000_00001 - 0.0033 17.4 1.7 1.1 9.3 0.1 2.1 1 1 1 2 2 2 2 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AVFM020000_00001 - 0.0038 17.3 1.4 0.87 9.8 0.2 2.2 2 0 0 2 2 2 2 Zinc ribbon domain zf-TFIIB PF13453.6 AVFM020000_00001 - 0.0042 16.4 0.8 0.53 9.7 0.1 2.2 2 0 0 2 2 2 1 Transcription factor zinc-finger DNA_ligase_ZBD PF03119.16 AVFM020000_00001 - 0.0048 16.9 1.8 0.046 13.7 0.1 2.2 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain NOB1_Zn_bind PF08772.11 AVFM020000_00001 - 0.0056 16.8 2.2 0.77 10.0 0.1 2.1 1 1 1 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.6 AVFM020000_00001 - 0.01 15.8 1.1 0.51 10.3 0.0 2.6 2 1 1 3 3 3 0 Nudix N-terminal Elf1 PF05129.13 AVFM020000_00001 - 0.013 15.6 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-NADH-PPase PF09297.11 AVFM020000_00001 - 0.014 15.0 2.0 0.31 10.7 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 AVFM020000_00001 - 0.016 15.2 1.0 0.027 14.5 1.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-DNL PF05180.12 AVFM020000_00001 - 0.017 15.1 0.6 0.035 14.0 0.6 1.5 1 1 0 1 1 1 0 DNL zinc finger Zn_ribbon_SprT PF17283.2 AVFM020000_00001 - 0.024 14.6 2.5 0.041 13.8 2.5 1.4 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DpnI PF06044.12 AVFM020000_00001 - 0.033 13.8 0.4 0.042 13.5 0.4 1.1 1 0 0 1 1 1 0 Dam-replacing family zf-C4_Topoisom PF01396.19 AVFM020000_00001 - 0.033 14.0 1.9 3.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.6 AVFM020000_00001 - 0.042 13.6 3.5 3.5 7.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 AVFM020000_00001 - 0.046 14.0 2.6 1.3 9.3 0.2 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 AVFM020000_00001 - 0.07 12.6 3.3 0.68 9.5 3.3 2.2 1 1 0 1 1 1 0 TFIIB zinc-binding HypA PF01155.19 AVFM020000_00001 - 0.079 13.0 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pox_E10 PF04805.12 AVFM020000_00001 - 0.12 12.2 1.0 5.8 6.9 0.0 2.0 1 1 1 2 2 2 0 E10-like protein conserved region zf-trcl PF13451.6 AVFM020000_00001 - 0.13 12.2 3.1 0.74 9.8 2.5 2.0 1 1 0 1 1 1 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 AVFM020000_00001 - 0.15 12.5 1.7 9.7 6.8 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.12 AVFM020000_00001 - 0.2 12.0 1.9 1.9 8.9 0.1 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_10 PF18414.1 AVFM020000_00001 - 0.43 10.2 0.2 0.43 10.2 0.2 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger DUF3797 PF12677.7 AVFM020000_00001 - 0.49 10.3 6.6 2.8 7.9 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.6 AVFM020000_00001 - 0.64 9.5 5.6 1.8 8.1 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain GTP_EFTU PF00009.27 AVFM020000_00002 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AVFM020000_00002 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AVFM020000_00002 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AVFM020000_00002 - 1.3e-12 47.6 0.1 2.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AVFM020000_00002 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AVFM020000_00002 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AVFM020000_00002 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 AVFM020000_00002 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AVFM020000_00002 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 AVFM020000_00002 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B TnpV PF14198.6 AVFM020000_00003 - 2.8e-43 146.4 0.5 3.2e-43 146.2 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV VirB8 PF04335.13 AY190284_00001 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 AY190284_00001 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 AY190285_00001 - 2.8e-55 187.3 1.9 4.6e-55 186.6 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 AY190286_00001 - 5.8e-30 104.5 0.0 6.6e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 AY190286_00001 - 0.0049 16.0 0.1 0.0062 15.7 0.1 1.1 1 0 0 1 1 1 1 HaeIII restriction endonuclease T2SSE PF00437.20 AY190287_00001 - 6.4e-54 182.8 0.0 7.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AY190287_00001 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AY190287_00001 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AY190287_00001 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 AY190287_00001 - 0.0014 18.9 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AY190287_00001 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AY190287_00001 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 AY190287_00001 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 AY190287_00001 - 0.0049 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 AY190287_00001 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 AY190287_00001 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 AY190287_00001 - 0.0088 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 AY190287_00001 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 AY190287_00001 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 AY190287_00001 - 0.022 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 AY190287_00001 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 AY190287_00001 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 AY190287_00001 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 AY190287_00001 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 AY190287_00001 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 AY190287_00001 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AY190287_00001 - 0.039 13.2 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 AY190287_00001 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 AY190287_00001 - 0.063 11.9 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 AY190287_00001 - 0.065 13.6 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 AY190287_00001 - 0.085 12.8 0.4 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 AY190287_00001 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 AY190287_00001 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 AY190287_00001 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AY190287_00001 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AY190287_00001 - 0.29 11.6 3.1 0.32 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain Phage_pRha PF09669.10 AY190288_00001 - 1.8e-23 82.9 0.1 5.3e-23 81.4 0.1 1.8 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) GTP_EFTU PF00009.27 AY190525_00001 - 9e-59 198.3 0.3 1.2e-58 197.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AY190525_00001 - 2.6e-23 82.1 0.0 9.7e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AY190525_00001 - 1.1e-16 60.6 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AY190525_00001 - 1.3e-12 47.6 0.1 2.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AY190525_00001 - 1e-06 28.8 0.1 2.4e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AY190525_00001 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AY190525_00001 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 AY190525_00001 - 0.021 14.1 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AY190525_00001 - 0.043 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 AY394560_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AY394560_00001 - 3.7e-23 81.6 0.0 9.7e-23 80.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AY394560_00001 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AY394560_00001 - 1.3e-13 50.8 0.1 2.8e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AY394560_00001 - 1.3e-06 28.5 0.2 4.6e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RF3_C PF16658.5 AY394560_00001 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AY394560_00001 - 0.012 16.0 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Septin PF00735.18 AY394560_00001 - 0.02 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AY394560_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 AY394560_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 AY394560_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 AY394560_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 AY394560_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 AY394560_00005 - 0.019 15.1 0.2 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 AY394560_00006 - 0.0057 16.0 1.4 0.0057 16.0 1.4 2.0 3 0 0 3 3 3 1 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 AY394560_00006 - 1.9 7.5 5.4 2.3 7.2 5.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LysE PF01810.18 AY394560_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 AY394560_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 AY394560_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 AY394560_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 AY394560_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 AY394560_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 AY394560_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 AY394560_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 AY394560_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 AY394560_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 AY394560_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 AY394560_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 AY394560_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 AY394560_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 AY394560_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 AY394560_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 AY394560_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 AY394560_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 AY394560_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 AY394560_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 AY394560_00012 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 AY394560_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AY394560_00012 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AY394560_00012 - 9.2e-06 25.5 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 AY394560_00012 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 AY394560_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 AY394560_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 AY394560_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 AY394560_00014 - 0.00022 21.6 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AY394560_00014 - 0.0032 17.7 0.0 0.0079 16.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 AY394560_00014 - 0.0091 16.0 0.3 0.017 15.2 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 AY394560_00015 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 AY394560_00016 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 AY394560_00016 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 AY394560_00016 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 AY394560_00016 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 AY394560_00016 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 AY394560_00017 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 AY394560_00017 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 AY394560_00017 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 AY394560_00019 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 AY394560_00019 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 AY394560_00019 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 AY394560_00019 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 AY394560_00020 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 AY394560_00021 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 AY394560_00021 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 AY394560_00021 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 AY394560_00023 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 AY394560_00024 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 AY394560_00025 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AY394560_00025 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 AY394560_00025 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 AY394560_00025 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 AY394560_00025 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 AY394560_00025 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 AY394560_00025 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 AY394560_00026 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 AY394560_00026 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 AY394560_00026 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 AY394560_00026 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 AY394560_00027 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.8 1 1 1 2 2 2 2 CRISPR associated protein Cas2 TrbC PF04956.13 AY394560_00029 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 AY394560_00029 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 AY394560_00030 - 7.1e-51 173.2 0.4 1.6e-50 172.1 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 AY394560_00030 - 2.6e-21 75.7 1.0 4.4e-21 74.9 1.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 AY394560_00030 - 0.046 13.2 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 AY394560_00031 - 1.8e-31 108.5 0.0 2.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Y_Y_Y PF07495.13 AY394560_00031 - 0.1 12.6 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PBECR2 PF18810.1 AY394560_00032 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 AY394560_00033 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 AY394560_00034 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 AY394560_00034 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 AY394560_00034 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 AY394560_00034 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 AY394560_00035 - 1e-28 101.1 13.2 1.4e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 AY394560_00035 - 0.0082 16.3 2.4 0.021 15.0 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 AY394560_00035 - 0.016 15.9 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain KMP11 PF03037.16 AY394560_00035 - 0.02 15.7 0.1 0.17 12.7 0.0 2.6 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 AATF-Che1 PF13339.6 AY394560_00035 - 0.023 15.3 12.3 0.028 15.1 5.0 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Tissue_fac PF01108.17 AY394560_00035 - 0.029 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Tissue factor Allexi_40kDa PF05549.11 AY394560_00035 - 1.2 8.6 6.3 1.2 8.6 2.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 AY394560_00036 - 1.4e-29 103.5 34.4 1.4e-29 103.5 34.4 1.7 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 AY394560_00036 - 0.097 12.5 1.3 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 AY394560_00037 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 AY394560_00037 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 AY394560_00037 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 AY394560_00038 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 AY394560_00038 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 AY394560_00039 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 AY394560_00039 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 AY394560_00039 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 AY394560_00040 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 AY394560_00040 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 AY394560_00041 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AY394560_00041 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AY394560_00041 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AY394560_00041 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 AY394560_00041 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AY394560_00041 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 AY394560_00041 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AY394560_00041 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 AY394560_00041 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 AY394560_00041 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 AY394560_00041 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 AY394560_00041 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 AY394560_00041 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AY394560_00041 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 AY394560_00041 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 AY394560_00041 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AY394560_00041 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 AY394560_00041 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 AY394560_00041 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 AY394560_00041 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AY394560_00041 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 AY394560_00041 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 AY394560_00041 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 AY394560_00041 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 AY394560_00041 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 AY394560_00041 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 AY394560_00041 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 AY394560_00041 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 AY394560_00041 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 AY394560_00041 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AY394560_00041 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AY394560_00041 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 AY394560_00042 - 1.4e-105 353.8 0.1 1.9e-105 353.4 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AY394560_00042 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AY394560_00042 - 6.2e-16 58.3 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 AY394560_00043 - 1e-16 61.2 0.1 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 AY394560_00043 - 0.062 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 AY394560_00044 - 9.5e-39 132.8 1.2 1.2e-38 132.5 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 AY394560_00045 - 0.028 14.2 2.2 0.033 14.0 0.3 2.0 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 AY394560_00045 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family TACC_C PF05010.14 AY394560_00045 - 2.3 8.0 10.0 3.6 7.3 7.9 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 AY394560_00045 - 4.6 7.4 12.1 50 4.0 9.2 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT20 PF14931.6 AY394560_00045 - 5.4 7.2 10.4 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CdhD PF03599.16 AY394560_00047 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 AY394560_00047 - 0.028 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 AY394560_00047 - 0.12 12.6 0.1 0.12 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized YnfE-like Topoisom_bac PF01131.20 AY394560_00048 - 2.7e-97 326.4 7.4 3.8e-97 325.9 7.4 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AY394560_00048 - 7.1e-12 45.5 2.2 1.4e-11 44.5 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 AY394560_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 AY394560_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 AY394560_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 AY394560_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 AY394560_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 AY394560_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 AY394560_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 AY394560_00048 - 0.096 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 AY394560_00048 - 0.1 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 AY394560_00048 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 AY394560_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 AY394560_00048 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 AY394560_00048 - 0.74 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 AY394560_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 AY394560_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 AY394560_00049 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 AY394560_00049 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 AY394561_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AY394561_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AY394561_00001 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AY394561_00001 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AY394561_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AY394561_00001 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AY394561_00001 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 AY394561_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AY394561_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 AY394561_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 AY394561_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 AY394561_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 AY394561_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 AY394561_00005 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 AY394561_00005 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 AY394561_00006 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 AY394561_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 AY394561_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 AY394561_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 AY394561_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 AY394561_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 AY394561_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 AY394561_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 AY394561_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 AY394561_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 AY394561_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 AY394561_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 AY394561_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 AY394561_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 AY394561_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 AY394561_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 AY394561_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 AY394561_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 AY394561_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 AY394561_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 AY394561_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 AY394561_00012 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 AY394561_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AY394561_00012 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AY394561_00012 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 AY394561_00012 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 AY394561_00013 - 0.0008 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AY394561_00013 - 0.033 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 AY394561_00014 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 AY394561_00015 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 AY394561_00015 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 AY394561_00015 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 AY394561_00015 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 AY394561_00015 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 AY394561_00016 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 AY394561_00016 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 AY394561_00016 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 AY394561_00018 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 AY394561_00019 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 AY394561_00019 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 AY394561_00019 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 AY394561_00019 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 AY394561_00020 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 AY394561_00021 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 AY394561_00021 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 AY394561_00021 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 AY394561_00021 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 AY394561_00022 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 AY394561_00022 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 AY394561_00022 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 AY394561_00024 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 AY394561_00025 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 AY394561_00026 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AY394561_00026 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 AY394561_00026 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 AY394561_00026 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AY394561_00026 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 AY394561_00026 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 AY394561_00026 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 AY394561_00027 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 AY394561_00027 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 AY394561_00027 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 AY394561_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 AY394561_00028 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 AY394561_00028 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 AY394561_00030 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 AY394561_00030 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 AY394561_00031 - 4.8e-50 170.5 0.5 1.1e-49 169.4 0.5 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 AY394561_00031 - 6.8e-21 74.3 1.2 1.2e-20 73.5 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 AY394561_00031 - 0.045 13.2 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 AY394561_00033 - 1.5e-21 76.7 0.1 2.6e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 AY394561_00034 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 AY394561_00034 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 AY394561_00034 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 AY394561_00034 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 AY394561_00034 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 AY394561_00034 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 AY394561_00035 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 AY394561_00036 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 AY394561_00036 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 AY394561_00037 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 AY394561_00037 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 AY394561_00037 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 AY394561_00037 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 AY394561_00037 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 AY394561_00037 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 AY394561_00037 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 AY394561_00038 - 1.4e-31 110.0 32.1 1.9e-31 109.5 32.1 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Trep_dent_lipo PF09710.10 AY394561_00039 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 AY394561_00039 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 AY394561_00040 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 AY394561_00040 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 AY394561_00041 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 AY394561_00041 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 AY394561_00042 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 AY394561_00042 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 AY394561_00043 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AY394561_00043 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AY394561_00043 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AY394561_00043 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 AY394561_00043 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AY394561_00043 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AY394561_00043 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 AY394561_00043 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 AY394561_00043 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 AY394561_00043 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 AY394561_00043 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 AY394561_00043 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 AY394561_00043 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 AY394561_00043 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 AY394561_00043 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 AY394561_00043 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 AY394561_00043 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 AY394561_00043 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 AY394561_00043 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 AY394561_00043 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 AY394561_00043 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AY394561_00043 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 AY394561_00043 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 AY394561_00043 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 AY394561_00043 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 AY394561_00043 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 AY394561_00043 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 AY394561_00043 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 AY394561_00043 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AY394561_00043 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AY394561_00043 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 AY394561_00044 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AY394561_00044 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AY394561_00044 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 AY394561_00044 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 AY394561_00045 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 AY394561_00045 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 AY394561_00045 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 AY394561_00045 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 AY394561_00046 - 5.7e-29 101.1 0.5 6.4e-29 100.9 0.5 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 AY394561_00047 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 AY394561_00047 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 AY394561_00047 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 AY394561_00049 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 AY394561_00050 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AY394561_00050 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 AY394561_00050 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 AY394561_00050 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 AY394561_00050 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 AY394561_00050 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 AY394561_00050 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 AY394561_00050 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 AY394561_00050 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 AY394561_00050 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 AY394561_00050 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 AY394561_00050 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 AY394561_00050 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 AY394561_00050 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 AY394561_00050 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 AY394561_00050 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 AY394561_00050 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 AY394561_00051 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 AY394561_00051 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Adenyl_transf PF04439.12 AY701528_00002 - 1.2e-115 385.5 6.3 1.3e-115 385.3 6.3 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase PcfJ PF14284.6 AY701528_00003 - 2.9e-05 24.0 2.2 2.9e-05 24.0 2.2 1.6 2 0 0 2 2 2 1 PcfJ-like protein Intein_splicing PF14890.6 AY701528_00003 - 0.0053 16.7 3.0 0.015 15.3 3.0 1.9 1 1 0 1 1 1 1 Intein splicing domain GTP_EFTU PF00009.27 AY701528_00005 - 8.9e-59 198.3 0.3 1.2e-58 197.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AY701528_00005 - 2.6e-23 82.1 0.0 9.7e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AY701528_00005 - 8.5e-17 61.0 0.0 2.4e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AY701528_00005 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AY701528_00005 - 9.7e-07 28.9 0.1 2.4e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AY701528_00005 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AY701528_00005 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 AY701528_00005 - 0.021 14.1 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AY701528_00005 - 0.043 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF4111 PF13427.6 AY701528_00007 - 2.6e-26 91.8 0.0 1.1e-25 89.7 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 AY701528_00007 - 1.1e-09 38.2 0.0 5.4e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AY701528_00007 - 3e-06 27.4 0.0 6.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 AY701528_00007 - 0.00019 21.4 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain MdcG PF10620.9 AY701528_00007 - 0.2 11.4 0.1 0.67 9.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG AAA_18 PF13238.6 AY701528_00008 - 4.8e-14 53.0 0.0 6.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AY701528_00008 - 2.4e-10 40.8 0.0 2.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 AY701528_00008 - 7.5e-10 38.9 0.0 1.4e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 AY701528_00008 - 1.5e-07 30.9 0.0 3.6e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 AY701528_00008 - 1.1e-05 25.8 0.1 7.7e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 AY701528_00008 - 2.1e-05 25.0 0.0 3.7e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AY701528_00008 - 0.00017 21.9 0.0 0.0004 20.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AY701528_00008 - 0.00023 21.4 0.0 0.00099 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 AY701528_00008 - 0.0008 19.4 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AY701528_00008 - 0.0023 17.7 0.1 0.0057 16.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 AY701528_00008 - 0.0023 18.3 0.0 0.0042 17.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 AY701528_00008 - 0.0028 18.1 0.2 0.0032 18.0 0.2 1.5 1 1 0 1 1 1 1 ABC transporter KTI12 PF08433.10 AY701528_00008 - 0.0044 16.5 0.1 0.0092 15.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 AY701528_00008 - 0.0046 17.4 0.0 0.0056 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 AY701528_00008 - 0.0048 16.2 0.4 0.0056 16.0 0.4 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 AY701528_00008 - 0.0076 16.2 0.4 2.2 8.2 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 AY701528_00008 - 0.0079 16.1 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase Rad17 PF03215.15 AY701528_00008 - 0.0086 16.0 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain T2SSE PF00437.20 AY701528_00008 - 0.0086 15.2 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 AY701528_00008 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AY701528_00008 - 0.0098 15.3 1.3 0.017 14.5 0.1 1.9 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 AY701528_00008 - 0.0099 15.6 0.8 0.014 15.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 AY701528_00008 - 0.011 15.3 0.1 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 SRP54 PF00448.22 AY701528_00008 - 0.014 15.1 0.2 0.031 13.9 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DnaB_C PF03796.15 AY701528_00008 - 0.016 14.6 0.6 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 AY701528_00008 - 0.021 14.8 0.6 0.049 13.5 0.3 1.7 2 0 0 2 2 2 0 NTPase TIP49 PF06068.13 AY701528_00008 - 0.034 13.3 0.3 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 AY701528_00008 - 0.038 13.7 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain dNK PF01712.19 AY701528_00008 - 0.039 13.8 0.2 0.94 9.3 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 AY701528_00008 - 0.055 13.6 1.9 2.5 8.2 0.1 2.2 1 1 1 2 2 2 0 Cytidylate kinase-like family PhoH PF02562.16 AY701528_00008 - 0.065 12.7 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 AY701528_00008 - 0.067 13.0 1.4 0.12 12.1 1.4 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AY701528_00008 - 0.082 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 AY701528_00008 - 0.084 12.4 0.2 0.5 9.9 0.1 2.2 3 0 0 3 3 3 0 AAA domain MKT1_N PF12247.8 AY701528_00008 - 0.088 13.2 0.0 0.27 11.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication ATP-synt_ab PF00006.25 AY701528_00008 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 AY701528_00008 - 0.12 12.3 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AY701528_00008 - 0.14 11.7 0.3 0.28 10.7 0.1 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region CoaE PF01121.20 AY701528_00008 - 0.16 11.7 0.9 9.3 5.9 0.1 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase Hydin_ADK PF17213.3 AY701528_00008 - 0.28 11.4 1.0 0.4 10.9 0.2 1.6 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain DpnD-PcfM PF14207.6 AY701528_00008 - 2.7 8.0 4.9 14 5.7 0.3 2.9 3 0 0 3 3 3 0 DpnD/PcfM-like protein APH PF01636.23 AY701528_00009 - 1.2e-15 58.1 0.0 7.6e-15 55.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AY701528_00009 - 1.8e-09 37.5 5.3 3.4e-09 36.6 4.7 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 AY701528_00009 - 0.00022 20.7 0.7 0.00022 20.7 0.7 2.1 2 1 1 3 3 3 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 AY701528_00009 - 0.023 13.9 0.6 0.05 12.8 0.3 1.7 2 0 0 2 2 2 0 Fructosamine kinase Ribosomal_S13 PF00416.22 AY701528_00009 - 0.029 14.8 1.8 0.076 13.4 0.1 2.4 2 1 0 3 3 3 0 Ribosomal protein S13/S18 YppF PF14178.6 AY701528_00009 - 0.37 10.7 4.0 1.1 9.2 0.1 2.9 1 1 1 2 2 2 0 YppF-like protein ABC2_membrane_3 PF12698.7 AY701528_00009 - 0.69 9.0 6.6 0.22 10.6 0.9 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein BLOC1_2 PF10046.9 AY701528_00009 - 3.3 8.1 9.1 1.1 9.6 0.3 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4111 PF13427.6 AY701528_00010 - 1.6e-23 82.9 0.0 5.6e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4111) NTP_transf_2 PF01909.23 AY701528_00010 - 1.2e-06 28.7 0.6 2.4e-06 27.7 0.5 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AY701528_00010 - 0.00032 20.7 0.1 0.00088 19.3 0.1 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Adenyl_cycl_N PF12633.7 AY701528_00010 - 0.022 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase NT domain Acetyltransf_1 PF00583.25 AY701528_00011 - 9e-17 61.4 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AY701528_00011 - 1.4e-09 38.0 0.0 1.8e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AY701528_00011 - 4.8e-08 33.3 0.1 7.8e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AY701528_00011 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AY701528_00011 - 0.0045 17.1 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 AY701528_00011 - 0.007 17.0 0.0 0.0082 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 AY701528_00011 - 0.034 13.8 0.0 0.04 13.6 0.0 1.3 1 1 0 1 1 1 0 MOZ/SAS family APH PF01636.23 AY701528_00012 - 2.3e-23 83.4 0.0 3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AY701528_00012 - 0.0019 17.8 1.2 0.0046 16.6 1.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase 120_Rick_ant PF12574.8 AY701528_00012 - 0.12 11.5 2.5 1.3 8.2 0.4 2.3 1 1 1 2 2 2 0 120 KDa Rickettsia surface antigen HTH_23 PF13384.6 AY701528_00013 - 0.0036 17.1 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 AY701528_00013 - 0.046 13.9 0.7 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AY701528_00013 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 AY701528_00013 - 0.097 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 AY701528_00013 - 0.12 12.4 0.1 0.31 11.0 0.1 1.8 1 1 0 1 1 1 0 HTH domain HU-CCDC81_euk_2 PF18289.1 AY701528_00013 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HTH_Tnp_ISL3 PF13542.6 AY701528_00013 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HxlR PF01638.17 AY701528_00014 - 2.7e-22 78.4 0.0 3.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 AY701528_00014 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AY701528_00014 - 0.00023 21.1 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 AY701528_00014 - 0.00035 20.4 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AY701528_00014 - 0.00061 19.6 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 MarR family PadR PF03551.14 AY701528_00014 - 0.0015 18.5 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AY701528_00014 - 0.0064 16.6 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF1495 PF07381.11 AY701528_00014 - 0.12 12.2 0.0 0.42 10.5 0.0 1.7 1 1 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Replic_Relax PF13814.6 AY701528_00014 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation Putative_PNPOx PF01243.20 AY701528_00015 - 4.3e-12 46.0 0.0 6.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 AY701528_00015 - 3.7e-06 26.6 0.0 4.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Pyridox_ox_2 PF12900.7 AY701528_00015 - 0.063 13.3 0.0 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase IstB_IS21 PF01695.17 AY701528_00016 - 1.2e-58 197.8 1.9 3.6e-58 196.2 0.2 1.9 1 1 1 2 2 2 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AY701528_00016 - 1.3e-08 35.0 0.6 1.3e-08 35.0 0.6 1.6 2 0 0 2 2 2 1 Bacterial dnaA protein RNA_helicase PF00910.22 AY701528_00016 - 1.7e-05 25.1 0.4 0.00047 20.5 0.0 2.3 2 0 0 2 2 2 1 RNA helicase PhoH PF02562.16 AY701528_00016 - 3.5e-05 23.4 0.0 8.2e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 AY701528_00016 - 5.3e-05 23.5 0.2 0.029 14.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 AY701528_00016 - 6.8e-05 23.3 0.1 0.00012 22.5 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AY701528_00016 - 7.7e-05 22.5 0.1 0.0051 16.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 AY701528_00016 - 8.1e-05 23.1 0.0 0.00015 22.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 AY701528_00016 - 0.00047 20.2 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 AY701528_00016 - 0.00062 19.5 0.7 0.0016 18.2 0.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AY701528_00016 - 0.00073 19.6 0.3 0.00073 19.6 0.3 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AY701528_00016 - 0.00099 18.7 0.1 0.0027 17.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AFG1_ATPase PF03969.16 AY701528_00016 - 0.0026 16.7 0.1 0.0036 16.2 0.1 1.2 1 0 0 1 1 1 1 AFG1-like ATPase NTPase_1 PF03266.15 AY701528_00016 - 0.0033 17.4 1.3 0.14 12.1 0.1 2.4 1 1 1 2 2 2 1 NTPase NACHT PF05729.12 AY701528_00016 - 0.0033 17.4 0.2 0.014 15.4 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 AY701528_00016 - 0.0075 15.9 0.3 0.077 12.6 0.0 2.5 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 AY701528_00016 - 0.014 15.4 0.1 0.045 13.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 AY701528_00016 - 0.016 15.1 1.3 0.037 13.9 0.0 2.1 2 1 1 3 3 2 0 RsgA GTPase Roc PF08477.13 AY701528_00016 - 0.032 14.5 0.0 0.088 13.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 AY701528_00016 - 0.045 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AY701528_00016 - 0.072 12.8 0.2 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 AY701528_00016 - 0.1 12.2 0.1 0.83 9.3 0.0 2.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 AY701528_00016 - 0.13 12.2 0.1 0.3 11.1 0.1 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 AY701528_00016 - 0.15 12.1 3.1 0.17 11.8 2.4 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit rve PF00665.26 AY701528_00017 - 1.7e-13 50.8 0.0 3.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Phage_portal PF04860.12 AY701528_00017 - 0.0087 15.3 0.8 0.18 11.0 0.0 2.2 1 1 1 2 2 2 2 Phage portal protein DDE_Tnp_IS1595 PF12762.7 AY701528_00018 - 3.8e-15 56.2 1.0 6.5e-15 55.5 1.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain Zn_Tnp_IS1595 PF12760.7 AY701528_00018 - 1.2e-06 28.4 1.3 3e-06 27.1 1.3 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 AY701528_00018 - 0.0007 19.3 6.9 0.0007 19.3 6.9 1.9 2 0 0 2 2 2 1 InsA N-terminal domain HTH_30 PF13556.6 AY701528_00018 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 AY701528_00018 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain PhnJ PF06007.11 AY701528_00018 - 0.061 12.3 0.1 0.12 11.3 0.1 1.4 1 1 0 1 1 1 0 Phosphonate metabolism protein PhnJ Lar_restr_allev PF14354.6 AY701528_00018 - 0.062 13.7 3.3 0.063 13.7 1.9 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 AY701528_00018 - 0.063 13.4 0.7 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 AY701528_00018 - 0.069 12.9 8.5 0.54 10.0 0.2 2.7 3 0 0 3 3 2 0 A2L zinc ribbon domain zf-C2H2 PF00096.26 AY701528_00018 - 0.22 12.0 0.2 0.22 12.0 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADK_lid PF05191.14 AY701528_00018 - 0.25 11.4 4.0 1.8 8.6 0.1 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.6 AY701528_00018 - 0.73 9.8 8.7 5.6 7.0 8.7 2.2 1 1 0 1 1 1 0 Nudix N-terminal DUF3268 PF11672.8 AY701528_00018 - 0.82 10.0 5.1 17 5.8 3.0 2.5 2 1 0 2 2 2 0 zinc-finger-containing domain TF_Zn_Ribbon PF08271.12 AY701528_00018 - 5.5 6.6 7.1 53 3.4 6.8 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding AAA_18 PF13238.6 AY701528_00019 - 1.9e-14 54.3 0.0 2.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AY701528_00019 - 3.6e-10 40.2 0.0 5.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 AY701528_00019 - 1.6e-09 37.9 0.0 3.1e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 AY701528_00019 - 1.6e-09 37.3 0.1 3.3e-09 36.3 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 AY701528_00019 - 7.3e-06 26.3 0.3 3.1e-05 24.3 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 AY701528_00019 - 1.1e-05 25.9 0.0 4.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AY701528_00019 - 1.8e-05 25.0 0.0 7.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 AY701528_00019 - 5.3e-05 23.7 0.1 0.00021 21.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AY701528_00019 - 0.00029 21.3 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 AY701528_00019 - 0.0011 18.3 0.2 0.0013 18.0 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 AY701528_00019 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AY701528_00019 - 0.0015 18.9 0.2 0.0032 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 AY701528_00019 - 0.0018 17.8 0.1 0.0044 16.5 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 AY701528_00019 - 0.0021 17.8 0.1 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AY701528_00019 - 0.0043 17.6 0.0 0.0046 17.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.13 AY701528_00019 - 0.0046 16.2 0.3 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain T2SSE PF00437.20 AY701528_00019 - 0.0056 15.8 0.0 0.0086 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 AY701528_00019 - 0.0071 16.1 0.1 0.0082 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 AY701528_00019 - 0.0082 15.5 0.7 0.018 14.4 0.1 1.8 2 0 0 2 2 2 1 KaiC APS_kinase PF01583.20 AY701528_00019 - 0.0099 15.8 0.0 0.073 13.0 0.0 2.0 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 AY701528_00019 - 0.013 15.1 0.1 0.034 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AY701528_00019 - 0.014 15.3 1.2 0.027 14.4 0.2 1.8 2 0 0 2 2 2 0 NTPase DnaB_C PF03796.15 AY701528_00019 - 0.017 14.5 0.7 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 AY701528_00019 - 0.017 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 AY701528_00019 - 0.023 14.5 0.0 0.066 12.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 AY701528_00019 - 0.024 14.4 1.4 0.066 13.0 1.4 1.8 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 AY701528_00019 - 0.025 14.9 0.2 0.025 14.9 0.2 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_7 PF12775.7 AY701528_00019 - 0.025 14.1 0.6 0.1 12.1 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 AY701528_00019 - 0.027 14.2 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArsA_ATPase PF02374.15 AY701528_00019 - 0.035 13.3 0.1 0.088 12.0 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase NACHT PF05729.12 AY701528_00019 - 0.035 14.0 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 AY701528_00019 - 0.041 13.6 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 AY701528_00019 - 0.043 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain MKT1_N PF12247.8 AY701528_00019 - 0.044 14.2 0.0 0.099 13.0 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication NB-ARC PF00931.22 AY701528_00019 - 0.047 12.9 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 AY701528_00019 - 0.059 13.3 0.1 3.8 7.4 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 AY701528_00019 - 0.067 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PG_binding_3 PF09374.10 AY701528_00019 - 0.071 13.4 0.1 1.1 9.5 0.0 2.4 2 1 1 3 3 2 0 Predicted Peptidoglycan domain IPT PF01745.16 AY701528_00019 - 0.077 12.4 0.2 0.25 10.7 0.1 1.8 2 0 0 2 2 2 0 Isopentenyl transferase PhoH PF02562.16 AY701528_00019 - 0.086 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 AY701528_00019 - 0.088 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 AY701528_00019 - 0.094 12.4 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.11 AY701528_00019 - 0.1 12.5 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 AY701528_00019 - 0.11 12.4 0.6 0.38 10.6 0.0 2.1 2 1 1 3 3 3 0 P-loop Nucleotide Kinase3 APH PF01636.23 AY701528_00020 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 AY701528_00020 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 AY701528_00020 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 AY701528_00020 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 AY701528_00020 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 AY701528_00020 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 AY701528_00021 - 4.2e-51 174.0 0.1 4.8e-51 173.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 AY701528_00022 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 AY701528_00023 - 5.6e-20 71.7 0.1 7.6e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AY701528_00023 - 1.7e-13 50.8 0.1 2.7e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AY701528_00023 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AY701528_00023 - 2e-09 37.8 1.3 2.4e-09 37.5 1.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AY701528_00023 - 0.0015 19.2 0.0 0.0019 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AY701528_00023 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AY701528_00023 - 0.011 15.8 0.0 0.044 13.9 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 AY701528_00023 - 0.031 14.0 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AY701528_00023 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 AY701528_00024 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AY701528_00024 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 AY701528_00024 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Y1_Tnp PF01797.16 AY701528_00025 - 1.5e-37 128.4 1.5 2e-37 128.0 1.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 AY701528_00026 - 4.6e-23 80.9 0.3 9.6e-23 79.9 0.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 AY701528_00026 - 6.7e-13 48.9 2.3 6.7e-13 48.9 2.3 2.0 2 1 0 2 2 2 1 Probable transposase HTH_OrfB_IS605 PF12323.8 AY701528_00026 - 3.3e-09 36.1 2.5 7.3e-09 35.0 2.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4428 PF14471.6 AY701528_00026 - 0.012 15.6 0.4 0.045 13.7 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prok-RING_1 PF14446.6 AY701528_00026 - 0.018 15.0 0.5 0.032 14.1 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Methyltr_RsmF_N PF17125.5 AY701528_00026 - 0.051 14.1 2.4 0.098 13.2 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Rpr2 PF04032.16 AY701528_00026 - 0.064 13.5 4.2 6.7 7.1 0.2 3.3 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 AY701528_00026 - 0.11 12.7 1.0 0.29 11.3 1.0 1.8 1 1 0 1 1 1 0 Zinc ribbon domain C1_2 PF03107.16 AY701528_00026 - 0.13 12.6 1.1 0.25 11.7 1.1 1.5 1 0 0 1 1 1 0 C1 domain Zn_Tnp_IS1595 PF12760.7 AY701528_00026 - 0.14 12.2 1.0 0.26 11.3 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 AY701528_00026 - 0.2 11.4 2.0 11 5.9 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 AY701528_00026 - 0.3 11.1 4.1 11 6.1 0.2 2.7 2 0 0 2 2 2 0 YhfH-like protein Rubredoxin_2 PF18073.1 AY701528_00026 - 0.53 10.1 1.7 3.2 7.6 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain A2L_zn_ribbon PF08792.10 AY701528_00026 - 1.2 8.9 5.1 6.4 6.6 5.1 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain AMIN PF11741.8 AY701528_00026 - 1.9 8.7 8.2 0.89 9.7 0.3 2.9 2 1 0 2 2 2 0 AMIN domain eIF-5_eIF-2B PF01873.17 AY701528_00026 - 2.6 7.9 7.7 1.1 9.2 1.5 3.0 2 1 0 2 2 2 0 Domain found in IF2B/IF5 NPA PF16469.5 AY701528_00027 - 0.057 14.0 6.1 0.06 13.9 6.1 1.0 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF1272 PF06906.11 AY701528_00028 - 0.0094 16.0 4.2 0.016 15.3 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Papo_T_antigen PF02380.15 AY701528_00028 - 0.011 15.8 6.4 0.017 15.2 6.4 1.4 1 1 0 1 1 1 0 T-antigen specific domain AAA_31 PF13614.6 AY701528_00029 - 7.9e-05 22.7 0.1 7.9e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AY701528_00029 - 0.0032 17.5 0.0 0.0033 17.5 0.0 1.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AY701528_00029 - 0.037 13.5 0.1 0.038 13.4 0.1 1.0 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Cas_DxTHG PF09455.10 AY701528_00030 - 0.045 13.3 3.0 0.075 12.6 1.7 1.8 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family adh_short PF00106.25 AY701528_00030 - 0.071 12.6 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 AY701528_00030 - 0.078 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Glycos_transf_2 PF00535.26 AY701528_00030 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Eco57I PF07669.11 AY701528_00032 - 1.9e-05 25.1 0.2 5.9e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 AY701528_00032 - 0.0027 17.3 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Acetyltransf_7 PF13508.7 AY714214_00002 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AY714214_00002 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 AY714214_00003 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 AY714214_00004 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 AY714214_00004 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 AY714214_00004 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 AY714214_00004 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 AY714214_00004 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 AY714214_00005 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 AY714214_00005 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 AY714214_00005 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 AY714214_00007 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 AY714214_00008 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 AY714214_00008 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 AY714214_00008 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 AY714214_00008 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 AY714214_00009 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 AY714214_00010 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 AY714214_00010 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 AY714214_00010 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 AY714214_00010 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 AY714214_00011 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 AY714214_00011 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 AY714214_00011 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 AY714214_00013 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 AY714214_00014 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 AY714214_00015 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 AY714214_00015 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 AY714214_00015 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 AY714214_00015 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AY714214_00015 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 AY714214_00015 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 AY714214_00015 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 AY714214_00016 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 AY714214_00016 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 AY714214_00016 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 AY714214_00016 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 AY714214_00017 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 AY714214_00017 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 AY714214_00019 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 AY714214_00019 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 AY714214_00020 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 AY714214_00020 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 AY714214_00020 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 AY714214_00021 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 AY714214_00022 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 AY714214_00022 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 AY714214_00022 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 AY714214_00022 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 AY714214_00022 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 AY714214_00022 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 AY714214_00023 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 AY714214_00024 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 AY714214_00024 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 AY714214_00025 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 AY714214_00025 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 AY714214_00025 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 AY714214_00025 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 AY714214_00025 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 AY714214_00025 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 AY714214_00025 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 AY714214_00026 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 AY714214_00026 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 AY714214_00026 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 AY714214_00027 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 AY714214_00027 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 AY714214_00028 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 AY714214_00028 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 AY714214_00029 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 AY714214_00029 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 AY714214_00030 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 AY714214_00030 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 AY714214_00031 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AY714214_00031 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AY714214_00031 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AY714214_00031 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 AY714214_00031 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AY714214_00031 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AY714214_00031 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 AY714214_00031 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 AY714214_00031 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 AY714214_00031 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 AY714214_00031 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 AY714214_00031 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 AY714214_00031 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 AY714214_00031 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 AY714214_00031 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 AY714214_00031 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 AY714214_00031 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 AY714214_00031 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 AY714214_00031 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 AY714214_00031 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 AY714214_00031 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AY714214_00031 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 AY714214_00031 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 AY714214_00031 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 AY714214_00031 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 AY714214_00031 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 AY714214_00031 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 AY714214_00031 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 AY714214_00031 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 AY714214_00031 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AY714214_00031 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 AY714214_00032 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 AY714214_00032 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 AY714214_00032 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 AY714214_00032 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 AY714214_00033 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 AY714214_00033 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 AY714214_00033 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 AY714214_00033 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 AY714214_00034 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 AY714214_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 AY714214_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 AY714214_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 AY714214_00037 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 AY714214_00038 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AY714214_00038 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 AY714214_00038 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 AY714214_00038 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 AY714214_00038 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 AY714214_00038 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 AY714214_00038 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 AY714214_00038 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 AY714214_00038 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 AY714214_00038 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 AY714214_00038 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 AY714214_00038 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 AY714214_00038 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 AY714214_00038 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 AY714214_00038 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 AY714214_00038 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 AY714214_00038 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 AY714214_00039 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 AY714214_00039 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 AY714214_00041 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AY714214_00041 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 AY714214_00041 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AY714214_00041 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AY714214_00041 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AY714214_00041 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AY714214_00041 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 AY714214_00041 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 AY714214_00041 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 AY714214_00041 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 AY714214_00042 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 AY714214_00044 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 AY714214_00044 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 AY714214_00045 - 0.039 14.1 0.2 4.3 7.5 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 AY714214_00046 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DUF1516 PF07457.11 AY714214_00047 - 0.0042 17.3 0.4 0.0049 17.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) LysE PF01810.18 AY714214_00047 - 0.0049 16.4 0.1 0.0057 16.1 0.1 1.1 1 0 0 1 1 1 1 LysE type translocator DUF2873 PF11395.8 AY714214_00047 - 1 9.3 0.1 1 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2873) S1_2 PF13509.6 AY714214_00048 - 0.093 12.8 0.5 0.85 9.7 0.1 2.0 1 1 1 2 2 2 0 S1 domain DUF4044 PF13253.6 AY714214_00049 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 AY714214_00049 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 AY714214_00049 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 AY714214_00049 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 AY714214_00049 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 AY714214_00050 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 AY714214_00050 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 AY714214_00051 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 AY714214_00051 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 AY714214_00051 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 AY714214_00051 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 AY714214_00051 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 AY714214_00052 - 5.4e-07 29.9 1.0 5.9e-07 29.8 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG PDDEXK_9 PF08011.11 AY714214_00053 - 0.017 15.0 0.2 0.032 14.1 0.2 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF5445 PF17520.2 AY714214_00054 - 1 9.2 12.2 1.3 8.9 11.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5445) DUF2362 PF10154.9 AY730723_00001 - 0.00027 20.0 30.9 0.00027 20.0 30.9 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2362) ORC4_C PF14629.6 AY730723_00001 - 0.0033 16.8 1.8 0.0033 16.8 1.8 2.2 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 4 C-terminus ApoO PF09769.9 AY730723_00001 - 1.4 8.9 14.2 9.7 6.2 2.4 4.4 3 2 1 4 4 4 0 Apolipoprotein O LysE PF01810.18 CM007863_00001 - 5.6e-05 22.7 0.0 6.7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CM007863_00001 - 0.002 18.3 0.3 0.0021 18.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) TerC PF03741.16 CM007863_00001 - 0.041 13.6 0.3 0.047 13.4 0.3 1.0 1 0 0 1 1 1 0 Integral membrane protein TerC family DUF5305 PF17231.2 CM007863_00001 - 0.077 12.4 0.6 0.1 12.0 0.2 1.4 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Saf_2TM PF18303.1 CM007863_00001 - 0.11 12.1 0.8 0.13 11.8 0.3 1.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain PetL PF05115.14 CM007863_00001 - 3.4 7.7 9.7 4 7.5 1.2 2.5 2 1 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Flp1_like PF16982.5 CM007863_00002 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 CM007863_00002 - 0.26 10.8 3.9 0.28 10.7 3.5 1.3 1 1 0 1 1 1 0 Negative regulator of p53/TP53 YopX PF09643.10 CM007863_00004 - 1.9e-14 53.8 7.2 4.7e-13 49.3 7.2 2.2 1 1 0 1 1 1 1 YopX protein RE_ApaLI PF09499.10 CM007863_00004 - 0.0081 15.9 0.6 0.0083 15.9 0.6 1.2 1 0 0 1 1 1 1 ApaLI-like restriction endonuclease DUF2583 PF10762.9 CM007863_00006 - 0.67 10.4 3.8 15 6.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Topoisom_bac PF01131.20 CM007863_00009 - 3.9e-97 325.9 7.9 5.4e-97 325.4 7.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CM007863_00009 - 1.9e-12 47.3 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CM007863_00009 - 1.6e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CM007863_00009 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CM007863_00009 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CM007863_00009 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CM007863_00009 - 0.055 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CM007863_00009 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CM007863_00009 - 0.089 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CM007863_00009 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CM007863_00009 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CM007863_00009 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CM007863_00009 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CM007863_00009 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CM007863_00009 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CM007863_00009 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 CM007863_00010 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CM007863_00012 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CM007863_00012 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CM007863_00012 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CM007863_00013 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CM007863_00014 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CM007863_00014 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CM007863_00014 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CM007863_00014 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CM007863_00015 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CM007863_00015 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CM007863_00015 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CM007863_00015 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 CM007863_00016 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CM007863_00016 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CM007863_00016 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CM007863_00016 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CM007863_00016 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CM007863_00016 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CM007863_00016 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CM007863_00016 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CM007863_00016 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CM007863_00016 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CM007863_00016 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CM007863_00016 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CM007863_00016 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CM007863_00016 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CM007863_00016 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CM007863_00016 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CM007863_00016 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CM007863_00016 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CM007863_00016 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CM007863_00016 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CM007863_00016 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CM007863_00016 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CM007863_00016 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CM007863_00016 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CM007863_00016 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CM007863_00016 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CM007863_00016 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CM007863_00016 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CM007863_00016 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CM007863_00016 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CM007863_00016 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CM007863_00017 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CM007863_00017 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CM007863_00018 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CM007863_00018 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 CM007863_00019 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CM007863_00019 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CM007863_00020 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CM007863_00020 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CM007863_00021 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CM007863_00021 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CM007863_00021 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 CM007863_00022 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CM007863_00022 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CM007863_00022 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CM007863_00022 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CM007863_00022 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 CM007863_00022 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 CM007863_00022 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 CM007863_00022 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 CM007863_00023 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CM007863_00023 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CM007863_00023 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CM007863_00023 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CM007863_00024 - 1.5e-25 89.2 0.1 1.8e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 CM007863_00025 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 CM007863_00026 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CM007863_00026 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CM007863_00026 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CM007863_00026 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CM007863_00026 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 CM007863_00027 - 4.1e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CM007863_00027 - 7.7e-21 74.1 0.9 1.4e-20 73.3 0.9 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CM007863_00027 - 2.9e-07 29.8 0.9 6.6e-07 28.6 0.9 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CM007863_00027 - 0.013 15.6 3.4 1.5 8.8 0.0 3.7 4 1 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 CM007863_00028 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CM007863_00028 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CM007863_00030 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Resolvase PF00239.21 CM007863_00031 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CM007863_00031 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CM007863_00031 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_25 PF13481.6 CM007863_00032 - 5.4e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CM007863_00032 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CM007863_00032 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CM007863_00032 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CM007863_00032 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CM007863_00032 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CM007863_00032 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 CM007863_00033 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CM007863_00034 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CM007863_00036 - 0.0052 16.8 2.6 0.0069 16.4 2.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 CM007863_00036 - 0.56 10.1 4.1 2 8.4 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 CM007863_00037 - 0.027 14.4 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 CM007863_00037 - 0.045 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 CM007863_00037 - 0.068 13.6 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF4223 PF13978.6 CM007863_00038 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) Toprim_3 PF13362.6 CM007863_00039 - 2.1e-08 34.4 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 CM007863_00039 - 0.14 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CM007863_00039 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2004 PF09406.10 CM007863_00040 - 0.12 12.7 3.0 0.62 10.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) Sds3 PF08598.11 CM007863_00042 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CM007863_00042 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CM007863_00042 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CM007863_00043 - 0.00011 22.1 5.7 0.067 13.2 0.7 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CM007863_00043 - 0.058 13.5 1.9 0.087 12.9 1.4 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DndE PF08870.11 CM007863_00043 - 0.31 11.3 5.7 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CM007863_00043 - 0.53 10.6 5.9 2.5 8.5 2.0 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 CM007863_00043 - 2 8.5 7.9 1 9.4 0.3 3.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Relaxase PF03432.14 CM007863_00044 - 4.3e-09 36.3 8.2 4.3e-09 36.3 8.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF2768 PF10966.8 CM007863_00045 - 0.053 14.0 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SNF2_N PF00176.23 CM007863_00046 - 3e-16 59.1 1.8 5.1e-16 58.3 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CM007863_00046 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CM007863_00046 - 9.6e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CM007863_00046 - 8.1e-06 25.7 2.5 0.0012 18.7 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CM007863_00046 - 2.6e-05 24.7 0.7 0.00023 21.6 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CM007863_00047 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 CM007863_00047 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 CM007863_00048 - 5.3e-05 23.2 0.6 0.001 19.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CM007863_00048 - 0.0012 18.9 0.5 0.0079 16.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Mur_ligase_C PF02875.21 CM007863_00048 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CM007863_00048 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CM007863_00049 - 0.00028 21.0 1.6 0.00035 20.7 1.6 1.4 1 0 0 1 1 1 1 T-antigen specific domain CEBP_ZZ PF16366.5 CM007863_00049 - 0.022 15.0 2.6 0.03 14.6 2.6 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1272 PF06906.11 CM007863_00049 - 0.049 13.7 3.8 0.074 13.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Lip_prot_lig_C PF10437.9 CM007865_00001 - 0.048 13.6 3.7 0.12 12.4 3.0 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus EptA_B_N PF08019.12 CM007865_00003 - 0.12 12.3 10.8 0.053 13.4 1.6 2.3 1 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB FeoB_associated PF12669.7 CM007865_00003 - 1.9 9.0 0.0 1.9 9.0 0.0 3.0 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DUF2070 PF09843.9 CM007865_00003 - 7.9 4.6 18.3 9.6 4.4 18.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Topoisom_bac PF01131.20 CM007865_00006 - 5.8e-97 325.3 7.7 8e-97 324.8 7.7 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CM007865_00006 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CM007865_00006 - 1.4e-08 34.4 14.8 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CM007865_00006 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CM007865_00006 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CM007865_00006 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CM007865_00006 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CM007865_00006 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CM007865_00006 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CM007865_00006 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain FLYWCH PF04500.16 CM007865_00006 - 0.14 12.3 3.1 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain HTH_34 PF13601.6 CM007865_00006 - 0.47 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CM007865_00006 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CM007865_00006 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CM007865_00006 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CM007865_00006 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CM007865_00006 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 CM007865_00007 - 0.055 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CM007865_00008 - 0.039 13.8 0.5 0.039 13.8 0.5 1.8 2 0 0 2 2 2 0 PRELI-like family DUF2304 PF10066.9 CM007865_00008 - 0.1 12.8 0.9 0.24 11.6 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Rsd_AlgQ PF04353.13 CM007865_00008 - 1.3 8.9 6.1 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CM007865_00009 - 2.6e-35 121.7 1.4 3.6e-35 121.2 1.4 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CM007865_00010 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CM007865_00010 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CM007865_00010 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CM007865_00011 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CM007865_00011 - 9.9e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CM007865_00011 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CM007865_00011 - 0.046 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 CM007865_00012 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CM007865_00012 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CM007865_00012 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CM007865_00012 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CM007865_00012 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CM007865_00012 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CM007865_00012 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CM007865_00012 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CM007865_00012 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CM007865_00012 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CM007865_00012 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CM007865_00012 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CM007865_00012 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CM007865_00012 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CM007865_00012 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CM007865_00012 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CM007865_00012 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CM007865_00012 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CM007865_00012 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CM007865_00012 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CM007865_00012 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CM007865_00012 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CM007865_00012 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CM007865_00012 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CM007865_00012 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CM007865_00012 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CM007865_00012 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CM007865_00012 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CM007865_00012 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CM007865_00012 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CM007865_00012 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CM007865_00013 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CM007865_00013 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CM007865_00014 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CM007865_00014 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 CM007865_00015 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CM007865_00015 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CM007865_00016 - 0.035 13.0 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CM007865_00016 - 1.5 8.6 5.2 2.6 7.9 5.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CM007865_00017 - 8.7e-31 107.4 31.2 8.7e-31 107.4 31.2 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T4SS PF07996.11 CM007865_00018 - 2.2e-28 100.0 14.0 2.9e-28 99.6 14.0 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CM007865_00018 - 0.0037 17.4 0.4 0.015 15.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CM007865_00018 - 0.0089 16.7 5.2 0.0089 16.7 5.2 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CM007865_00018 - 0.064 12.8 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CM007865_00018 - 0.07 13.8 0.9 0.07 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain DHR10 PF18595.1 CM007865_00018 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 CM007865_00018 - 5.8 7.2 12.9 1.7 8.9 0.3 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 IF2_N PF04760.15 CM007865_00019 - 6.5e-05 22.7 5.8 0.00049 19.9 2.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HTH_16 PF12645.7 CM007865_00019 - 0.013 15.5 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CM007865_00019 - 0.029 15.1 0.5 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor FliG_N PF14842.6 CM007865_00019 - 0.039 14.5 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain SSB PF00436.25 CM007865_00020 - 1.4e-25 89.3 0.1 1.8e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 CM007865_00021 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 CM007865_00022 - 6.9e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CM007865_00022 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CM007865_00022 - 0.031 13.9 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CM007865_00022 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CM007865_00022 - 0.56 10.3 5.4 7.7 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 CM007865_00023 - 3.6e-49 167.7 0.3 9e-49 166.4 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CM007865_00023 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CM007865_00023 - 3.8e-07 29.4 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CM007865_00023 - 0.024 14.7 4.5 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 CM007865_00024 - 1.2e-15 57.5 7.6 1.4e-15 57.3 7.6 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CM007865_00024 - 0.047 13.5 4.0 0.054 13.3 3.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CM007865_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CM007865_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 CM007865_00027 - 3.6e-33 114.7 0.7 4.5e-33 114.4 0.7 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CM007865_00027 - 0.027 14.2 1.2 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CM007865_00027 - 0.047 13.7 5.4 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CM007865_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 CM007865_00028 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CM007865_00028 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CM007865_00028 - 0.0021 17.8 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CM007865_00028 - 0.0072 15.7 0.0 0.058 12.7 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CM007865_00028 - 0.013 15.9 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CM007865_00028 - 0.2 11.7 2.0 0.95 9.5 2.0 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CM007865_00028 - 0.35 10.8 3.5 5.1 7.1 0.0 3.8 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) VASP_tetra PF08776.11 CM007865_00028 - 3.8 7.2 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicA_toxin PF07927.12 CM007865_00029 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CM007865_00030 - 4.2e-08 33.3 0.0 4.4e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CM007865_00032 - 0.0043 17.1 1.7 0.0054 16.8 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 CM007865_00032 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 CM007865_00033 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CM007865_00033 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 CM007865_00034 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CM007865_00034 - 0.017 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein Sds3 PF08598.11 CM007865_00036 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CM007865_00036 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CM007865_00036 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CM007865_00037 - 0.00012 22.0 7.0 0.043 13.8 1.2 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CM007865_00037 - 0.063 13.4 2.6 0.071 13.2 1.5 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 CM007865_00037 - 0.47 10.8 6.1 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 CM007865_00037 - 0.53 10.4 9.0 1.5 8.9 0.4 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CM007865_00037 - 0.57 10.5 7.1 0.61 10.4 1.8 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 CM007865_00038 - 7.8e-10 38.8 7.7 7.8e-10 38.8 7.7 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain YqaJ PF09588.10 CM007865_00038 - 0.03 14.5 3.9 0.24 11.6 0.4 3.0 2 1 1 3 3 3 0 YqaJ-like viral recombinase domain HTH_19 PF12844.7 CM007865_00039 - 6.3e-06 26.1 0.3 0.024 14.6 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 CM007865_00039 - 7.6e-06 25.9 0.0 6.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CM007865_00039 - 0.00035 20.6 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CM007865_00039 - 0.0024 17.4 0.1 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 CM007865_00039 - 0.0043 16.9 0.1 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_17 PF12728.7 CM007865_00039 - 0.028 14.6 0.0 0.4 10.9 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 CM007865_00039 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 CM007865_00039 - 0.046 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_26 PF13443.6 CM007865_00039 - 0.048 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Mga PF08280.11 CM007865_00039 - 0.049 13.7 2.0 1.7 8.7 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 CM007865_00039 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 CM007865_00039 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CM007865_00039 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Crp PF00325.20 CM007865_00039 - 0.17 11.6 0.1 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family SNF2_N PF00176.23 CM007865_00040 - 2.3e-16 59.4 3.1 2.9e-16 59.2 0.3 2.5 3 1 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CM007865_00040 - 3.2e-08 33.8 8.8 3.2e-08 33.8 8.8 4.1 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CM007865_00040 - 6.8e-07 29.6 1.6 2.4e-05 24.6 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CM007865_00040 - 9.8e-07 28.7 1.9 0.00054 19.8 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase BST2 PF16716.5 CM007865_00040 - 4.3 8.0 7.3 8.1 7.1 2.7 3.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Eco57I PF07669.11 CM007865_00041 - 1.2e-05 25.7 0.3 5e-05 23.8 0.3 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 CM007865_00041 - 0.004 16.7 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 CM007865_00042 - 8.5e-07 29.3 0.8 9.4e-07 29.1 0.8 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 CM007865_00043 - 7.8e-05 22.7 0.5 0.0011 19.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CM007865_00043 - 0.00097 19.2 0.8 0.0077 16.3 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CM007865_00043 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 CM007865_00043 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CM007865_00044 - 0.02 15.0 7.2 0.03 14.5 7.2 1.4 1 1 0 1 1 1 0 T-antigen specific domain DUF1272 PF06906.11 CM007865_00044 - 0.059 13.5 6.2 0.095 12.8 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CEBP_ZZ PF16366.5 CM007865_00044 - 0.14 12.4 6.2 0.19 12.0 6.2 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain LIM PF00412.22 CM007865_00044 - 0.23 11.7 8.9 0.4 10.9 8.9 1.4 1 0 0 1 1 1 0 LIM domain DUF5595 PF18077.1 CM007865_00044 - 0.9 9.7 5.1 0.19 11.9 1.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) LysE PF01810.18 CM007865_00045 - 5.1e-06 26.1 0.0 5.8e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CM007865_00045 - 0.00027 21.1 1.1 0.00031 20.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) Ac76 PF05814.11 CM007865_00045 - 0.0043 17.0 2.2 0.0049 16.8 2.2 1.1 1 0 0 1 1 1 1 Orf76 (Ac76) Saf_2TM PF18303.1 CM007865_00045 - 0.24 11.0 3.5 0.12 12.0 0.7 1.7 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF2873 PF11395.8 CM007865_00045 - 3.7 7.5 6.8 0.78 9.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2873) LPAM_1 PF08139.12 CM007865_00045 - 7.1 7.3 5.9 1.1 9.9 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Flp1_like PF16982.5 CM007865_00046 - 0.044 13.2 3.1 0.044 13.2 3.1 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 CM007865_00046 - 0.053 13.0 1.6 0.06 12.9 1.6 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 MAF_flag10 PF01973.18 CM007884_00001 - 1.3e-43 148.6 1.0 2.7e-43 147.6 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF115 KASH_CCD PF14662.6 CM007884_00001 - 0.0075 16.1 0.5 0.037 13.9 0.5 2.1 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 CM007884_00001 - 0.072 13.3 4.3 0.33 11.2 2.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MAF_flag10 PF01973.18 CM007884_00002 - 1.5e-42 145.2 1.3 2.9e-42 144.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF115 PspA_IM30 PF04012.12 CM007884_00002 - 0.054 13.1 2.0 0.084 12.4 2.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family FliE PF02049.18 CM007884_00002 - 0.086 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Sec2p PF06428.11 CM007884_00002 - 0.26 11.3 7.2 0.83 9.7 7.2 1.9 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p eIF-4B PF06273.11 CM007884_00002 - 1.3 8.0 4.0 1.9 7.5 4.0 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Mur_ligase_M PF08245.12 CM007885_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CM007885_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 CM007885_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CM007885_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CM007885_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 CM007885_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 CM007885_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 CM007885_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 CM007885_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 CM007885_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 CM007885_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 CM007885_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 CM007885_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 CM007885_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CM007885_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CM007885_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 CM007885_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 CM007885_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 CM007885_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 CM007885_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 CM007885_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 CM007885_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 CM007885_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 CM007885_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 CM007885_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 CM007885_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 CM007885_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CM007885_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 CM007885_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 CM007885_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 CM007885_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 CM007885_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 CM007885_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 CM007885_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 CM007885_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CM007885_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CM007885_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 CM007885_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 CM007885_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 CM007885_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 CM007885_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 CM007885_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CM007885_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CM007885_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CM007885_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CM007885_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 CM007885_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CM007885_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 CM007885_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 CM007885_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CM007885_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CM007885_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 CM007885_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 CM007885_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 CM007885_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 CM007885_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CM007885_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 CM007885_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 CM007885_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 CM007885_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 CM007885_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CM007885_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CM007885_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 CM007885_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 CM007885_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 CM007885_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CM007885_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 CM007885_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 CM007885_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 CM007885_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 CM007885_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 CM007885_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 CM007885_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 CM007885_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 CM007885_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 CM007885_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 CM007885_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 CM007885_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 CM007885_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 CM007885_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 CM007885_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain Mur_ligase_M PF08245.12 CM007886_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CM007886_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 CM007886_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CM007886_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CM007886_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 CM007886_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 CM007886_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 CM007886_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 CM007886_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 CM007886_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 CM007886_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 CM007886_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 CM007886_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 CM007886_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CM007886_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CM007886_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 CM007886_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 CM007886_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 CM007886_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 CM007886_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 CM007886_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 CM007886_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 CM007886_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 CM007886_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 CM007886_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 CM007886_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 CM007886_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CM007886_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 CM007886_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 CM007886_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 CM007886_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 CM007886_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 CM007886_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 CM007886_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 CM007886_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CM007886_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CM007886_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 CM007886_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 CM007886_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 CM007886_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 CM007886_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 CM007886_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CM007886_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CM007886_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CM007886_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CM007886_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 CM007886_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CM007886_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 CM007886_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 CM007886_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CM007886_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CM007886_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 CM007886_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 CM007886_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 CM007886_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 CM007886_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CM007886_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 CM007886_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 CM007886_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 CM007886_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 CM007886_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CM007886_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CM007886_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 CM007886_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 CM007886_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 CM007886_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CM007886_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 CM007886_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 CM007886_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 CM007886_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 CM007886_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 CM007886_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 CM007886_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 CM007886_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 CM007886_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 CM007886_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 CM007886_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 CM007886_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 CM007886_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 CM007886_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 CM007886_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain MAF_flag10 PF01973.18 CM007887_00001 - 3.7e-42 143.9 0.7 5.4e-42 143.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF115 Med15_fungi PF05397.12 CM007887_00001 - 0.011 16.0 0.7 0.15 12.4 0.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 Mur_ligase_M PF08245.12 CM007888_00001 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CM007888_00001 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF4570 PF15134.6 CM007888_00002 - 0.17 11.9 1.7 0.32 11.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) CTP_transf_3 PF02348.19 CM007888_00003 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 CM007888_00003 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 CM007888_00003 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain PALP PF00291.25 CM007888_00004 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 CM007888_00004 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 CM007888_00004 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain LpxK PF02606.14 CM007888_00005 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 CM007888_00005 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_synthase PF02540.17 CM007888_00006 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 CM007888_00006 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 CM007888_00006 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 CM007888_00006 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 CM007888_00006 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 CM007888_00006 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Lactamase_B PF00753.27 CM007888_00007 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CM007888_00007 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1129 PF06570.11 CM007888_00008 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) adh_short_C2 PF13561.6 CM007888_00009 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CM007888_00009 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CM007888_00009 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 CM007888_00009 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DHDPS PF00701.22 CM007888_00010 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 CM007888_00010 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Peptidase_M16_C PF05193.21 CM007888_00011 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CM007888_00011 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 CM007888_00011 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHO_dh PF01180.21 CM007888_00012 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 CM007888_00012 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 CM007888_00012 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family ABC_membrane PF00664.23 CM007888_00013 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CM007888_00013 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CM007888_00013 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CM007888_00013 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CM007888_00013 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 CM007888_00013 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CM007888_00013 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 CM007888_00013 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 CM007888_00013 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CM007888_00013 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CM007888_00013 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_1e PF01406.19 CM007888_00014 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CM007888_00014 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CM007888_00014 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 CM007888_00014 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 CM007888_00014 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 CM007888_00014 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 CM007888_00014 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) MurJ PF03023.14 CM007888_00015 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 CM007888_00015 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 FapA PF03961.13 CM007888_00016 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 CM007888_00016 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 CM007888_00016 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 CM007888_00016 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HHH_5 PF14520.6 CM007888_00017 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 CM007888_00017 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 CM007888_00017 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 CM007888_00017 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 CM007888_00017 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 CM007888_00017 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 CM007888_00017 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 CM007888_00017 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 CM007888_00017 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 CM007888_00017 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 CM007888_00017 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CM007888_00017 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Dala_Dala_lig_C PF07478.13 CM007888_00018 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 CM007888_00018 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 CM007888_00018 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 CM007888_00018 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CM007888_00018 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CM007888_00018 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PhdYeFM_antitox PF02604.19 CM007888_00019 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system W2 PF02020.18 CP000549_00001 - 0.037 14.2 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 CP000549_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP000549_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 CP000549_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 CP000549_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP000549_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP000549_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP000549_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP000549_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP000549_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP000549_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 CP000549_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP000549_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP000549_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP000549_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP000549_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP000549_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP000549_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP000549_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP000549_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP000549_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP000549_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP000549_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP000549_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP000549_00009 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP000549_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP000549_00009 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP000549_00009 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP000549_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 CP000549_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP000549_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 CP000549_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP000549_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP000549_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP000549_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP000549_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP000549_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 CP000549_00013 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP000549_00013 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP000549_00013 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 CP000549_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 CP000549_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP000549_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP000549_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP000549_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP000549_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 CP000549_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 CP000549_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 CP000549_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 CP000549_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 CP000549_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 CP000549_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 CP000549_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP000549_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP000549_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP000549_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP000549_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP000549_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 CP000549_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CP000549_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP000549_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 CP000549_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 CP000549_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP000549_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP000549_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP000549_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP000549_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP000549_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP000549_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP000549_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP000549_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP000549_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 CP000549_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 CP000549_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 CP000549_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP000549_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP000549_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP000549_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP000549_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP000549_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 CP000549_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP000549_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP000549_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 CP000549_00033 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP000549_00033 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP000549_00033 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 CP000549_00033 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 CP000549_00033 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 CP000549_00033 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 CP000549_00033 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 CP000549_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP000549_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP000549_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP000549_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP000549_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP000549_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP000549_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP000549_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP000549_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP000549_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP000549_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP000549_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP000549_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP000549_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP000549_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP000549_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP000549_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP000549_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP000549_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP000549_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP000549_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP000549_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP000549_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP000549_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP000549_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP000549_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP000549_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP000549_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP000549_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP000549_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP000549_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP000549_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP000549_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP000549_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP000549_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP000549_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP000549_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP000549_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP000549_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP000549_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP000549_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP000549_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP000549_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP000549_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP000549_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP000549_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP000549_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP000549_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP000549_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP000549_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP000549_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP000549_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP000549_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP000549_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP000549_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP000549_00046 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP000549_00046 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP000549_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP000549_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP000549_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP000549_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP000549_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP000549_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP000549_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP000549_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP000549_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP000549_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP000549_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP000549_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP000549_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP000549_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP000549_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP000549_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP000549_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 CP000549_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP000549_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP000549_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP000549_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP000549_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP000549_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP000549_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP000549_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP000549_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 CP000549_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 CP000549_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 CP004067_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP004067_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 CP004067_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP004067_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain DHHC PF01529.20 CP004067_00004 - 4.1 7.5 13.1 13 5.9 13.1 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4133 PF13571.6 CP004067_00004 - 5.6 7.4 7.4 7.5 7.0 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) DHHC PF01529.20 CP004067_00006 - 0.033 14.3 6.3 0.039 14.0 6.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase T4SS_CagC PF16943.5 CP004067_00006 - 0.046 13.9 0.2 0.056 13.6 0.2 1.1 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF4044 PF13253.6 CP004067_00008 - 0.035 13.6 0.8 0.062 12.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP004067_00008 - 0.065 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2070 PF09843.9 CP004067_00008 - 0.072 11.4 1.1 0.11 10.8 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP004067_00008 - 9.1 6.0 13.6 0.15 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP004067_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP004067_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) adh_short PF00106.25 CP004067_00010 - 0.034 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP004067_00010 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 CP004067_00011 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 CP004067_00011 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 CP004067_00012 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP004067_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP004067_00012 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP004067_00012 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP004067_00012 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 CP004067_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 CP004067_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 CP004067_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 CP004067_00014 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP004067_00014 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 CP004067_00014 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 CP004067_00014 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 CP004067_00014 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 CP004067_00014 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 CP004067_00015 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 CP004067_00016 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP004067_00017 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP004067_00017 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 CP004067_00017 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 CP004067_00017 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP004067_00017 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 CP004067_00018 - 1.1 9.1 11.3 0.26 11.1 5.3 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP004067_00018 - 1.4 9.3 6.9 0.31 11.3 1.2 2.1 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 CP004067_00018 - 1.7 8.7 15.5 0.15 12.1 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function Ribonuc_2-5A PF06479.12 CP004067_00022 - 0.065 13.4 5.2 0.2 11.9 5.2 1.9 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF5311 PF17238.2 CP004067_00022 - 0.065 13.1 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Toprim_3 PF13362.6 CP004067_00023 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP004067_00023 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP004067_00023 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP004067_00023 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP004067_00024 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 CP004067_00024 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 CP004067_00025 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 CP004067_00025 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 CP004067_00025 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP004067_00027 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP004067_00028 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP004067_00029 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP004067_00029 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP004067_00029 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP004067_00029 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP004067_00029 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP004067_00029 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP004067_00029 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 CP004067_00030 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP004067_00030 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP004067_00030 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 CP004067_00031 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 CP004067_00033 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP004067_00033 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP004067_00034 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP004067_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 CP004067_00035 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 CP004067_00035 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 CP004067_00035 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 CP004067_00036 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 CP004067_00037 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP004067_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP004067_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP004067_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP004067_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP004067_00039 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP004067_00039 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 CP004067_00039 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 CP004067_00039 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 CP004067_00040 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP004067_00040 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 CP004067_00040 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 CP004067_00040 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 CP004067_00041 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 CP004067_00042 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP004067_00042 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP004067_00043 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 CP004067_00044 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP004067_00044 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP004067_00045 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP004067_00045 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP004067_00045 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP004067_00045 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP004067_00045 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP004067_00045 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CP004067_00045 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CP004067_00045 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP004067_00045 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP004067_00045 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP004067_00045 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP004067_00045 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 CP004067_00045 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CP004067_00045 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 CP004067_00045 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 CP004067_00045 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CP004067_00045 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CP004067_00045 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 CP004067_00045 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 CP004067_00045 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CP004067_00045 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 CP004067_00045 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP004067_00045 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP004067_00045 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP004067_00045 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP004067_00045 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP004067_00045 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP004067_00045 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CP004067_00045 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CP004067_00045 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP004067_00045 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP004067_00045 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 CP004067_00046 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 CP004067_00047 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP004067_00047 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP004067_00047 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 CP004067_00047 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 CP004067_00047 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 CP004067_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP004067_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 CP004067_00049 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP004067_00050 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 CP004067_00050 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 CP004067_00051 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 CP004067_00051 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 CP004067_00051 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 CP004067_00052 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 CP004067_00053 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP004067_00053 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP004067_00053 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP004067_00053 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP004067_00053 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP004067_00053 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP004067_00053 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP004067_00053 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP004067_00053 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP004067_00053 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP004067_00053 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP004067_00053 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP004067_00053 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP004067_00053 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP004067_00053 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP004067_00053 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP004067_00053 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP004067_00054 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP004067_00054 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain APH PF01636.23 CP004067_00056 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CP004067_00056 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 CP004067_00056 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CP004067_00056 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 CP004067_00056 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 CP004067_00057 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP004067_00057 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP004067_00057 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP004067_00057 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP004067_00057 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP004067_00057 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP004067_00057 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP004067_00057 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP004067_00057 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 CP004067_00059 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 CP004067_00059 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 CP004067_00059 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 CP004067_00059 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 CP004067_00059 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 CP004067_00060 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 CP004067_00061 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 CP004067_00061 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 CP004067_00061 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 CP004067_00061 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 CP004067_00062 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 CP004067_00063 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CP004067_00063 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CP004067_00063 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CP004067_00063 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 CP004067_00063 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CP004067_00063 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CP004067_00063 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CP004067_00063 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CP004067_00063 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CP004067_00063 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CP004067_00063 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CP004067_00063 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CP004067_00063 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 CP004067_00063 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 CP004067_00063 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 CP004067_00063 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 CP004067_00063 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP004067_00063 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 CP004067_00063 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 CP004067_00063 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CP004067_00063 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 CP004067_00063 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 CP004067_00063 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CP004067_00063 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 CP004067_00063 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 CP004067_00063 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 CP004067_00063 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 CP004067_00063 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 CP004067_00063 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 CP004067_00063 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 CP004067_00063 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CP004067_00063 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 CP004067_00063 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CP004067_00063 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 CP004067_00063 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 CP004067_00063 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 CP004067_00063 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 CP004067_00064 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP004067_00064 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CP004067_00064 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 CP004067_00064 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 CP004067_00064 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 CP004067_00064 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 CP004067_00065 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 CP004067_00066 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 CP004067_00067 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CP004067_00067 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CP004067_00067 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CP004067_00067 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CP004067_00067 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CP004067_00067 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CP004067_00067 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CP004067_00067 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 CP004067_00068 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CP004067_00068 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CP004067_00068 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 CP004067_00069 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 CP004067_00069 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 CP004067_00069 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 CP004067_00070 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 CP004067_00070 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 CP004067_00070 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain W2 PF02020.18 CP007180_00001 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 CP007180_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP007180_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 CP007180_00003 - 0.0072 15.7 2.9 0.0072 15.7 2.9 1.6 2 0 0 2 2 2 1 Putative Flagellin, Flp1-like, domain Y1_Tnp PF01797.16 CP007180_00004 - 4e-36 123.8 1.9 4.7e-36 123.6 1.9 1.1 1 0 0 1 1 1 1 Transposase IS200 like Symplekin_C PF12295.8 CP007180_00004 - 0.042 14.0 0.2 0.049 13.7 0.2 1.1 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal DUF4974 PF16344.5 CP007180_00004 - 0.47 10.5 3.6 0.16 12.0 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) OrfB_Zn_ribbon PF07282.11 CP007180_00005 - 3.2e-21 75.0 0.5 6.9e-21 73.9 0.5 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 CP007180_00005 - 2.4e-20 71.7 1.5 4.8e-20 70.8 1.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 CP007180_00005 - 7.6e-20 71.3 2.2 1.9e-19 70.0 2.2 1.6 1 0 0 1 1 1 1 Probable transposase HypA PF01155.19 CP007180_00005 - 0.19 11.7 0.7 0.42 10.6 0.7 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 CP007180_00005 - 0.32 11.1 1.5 1.3 9.2 1.5 2.1 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 CP007180_00005 - 2.3 7.7 5.7 16 5.0 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CP007180_00005 - 3.9 7.5 5.0 3.2 7.8 2.0 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ima1_N PF09779.9 CP007180_00005 - 5 8.0 7.5 1.7 9.5 0.7 2.9 2 1 1 3 3 3 0 Ima1 N-terminal domain LysE PF01810.18 CP007180_00006 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP007180_00006 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP007180_00006 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP007180_00006 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP007180_00006 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP007180_00006 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP007180_00006 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP007180_00006 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP007180_00006 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 CP007180_00007 - 0.0042 16.6 1.2 0.0059 16.1 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4044) NPA PF16469.5 CP007180_00008 - 0.057 14.0 6.1 0.06 13.9 6.1 1.0 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Papo_T_antigen PF02380.15 CP007180_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP007180_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP007180_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP007180_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP007180_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP007180_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP007180_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP007180_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP007180_00012 - 1.7e-16 59.9 1.2 4e-16 58.7 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP007180_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP007180_00012 - 9.6e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP007180_00012 - 6.3e-06 26.1 1.8 0.0012 18.7 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP007180_00012 - 1.5e-05 25.5 0.7 0.00015 22.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 CP007180_00013 - 1.1e-09 38.9 1.0 4.7e-09 36.9 1.0 2.0 1 1 0 1 1 1 1 NYN domain HTH_19 PF12844.7 CP007180_00014 - 7.3e-06 25.9 0.1 0.012 15.6 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CP007180_00014 - 7.9e-06 25.8 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CP007180_00014 - 0.00077 19.5 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CP007180_00014 - 0.0073 15.8 0.0 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CP007180_00014 - 0.0088 16.1 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP007180_00014 - 0.01 15.7 0.2 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 CP007180_00014 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CP007180_00014 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 CP007180_00014 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 CP007180_00014 - 0.073 12.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Relaxase PF03432.14 CP007180_00015 - 4.1e-10 39.7 7.6 4.1e-10 39.7 7.6 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP007180_00016 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP007180_00016 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP007180_00016 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP007180_00016 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP007180_00016 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Sds3 PF08598.11 CP007180_00017 - 0.027 14.5 5.8 0.032 14.3 5.8 1.1 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP007180_00017 - 0.21 11.4 8.2 0.23 11.3 5.3 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3671 PF12420.8 CP007180_00017 - 4.6 7.3 14.1 0.42 10.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function CdiI PF07262.11 CP007180_00017 - 8.8 6.1 12.2 16 5.3 12.2 1.5 1 1 0 1 1 1 0 CDI immunity protein DUF2400 PF09674.10 CP007180_00019 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 CP007180_00020 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP007180_00020 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP007180_00020 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP007180_00020 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP007180_00021 - 0.0028 17.6 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 CP007180_00022 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 CP007180_00022 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 CP007180_00022 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP007180_00024 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP007180_00025 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP007180_00026 - 5.4e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP007180_00026 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP007180_00026 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP007180_00026 - 0.0088 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP007180_00026 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP007180_00026 - 0.21 11.7 2.2 1.1 9.4 2.2 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP007180_00026 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 CP007180_00027 - 1.3e-33 116.2 0.8 2.2e-33 115.4 0.8 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain CRISPR_Cas2 PF09827.9 CP007180_00027 - 0.0016 18.5 0.0 0.016 15.3 0.0 2.6 1 1 0 1 1 1 1 CRISPR associated protein Cas2 PAS_11 PF14598.6 CP007180_00027 - 0.0032 17.6 1.2 0.023 14.8 0.4 2.3 2 0 0 2 2 2 1 PAS domain Occludin_ELL PF07303.13 CP007180_00027 - 0.12 13.1 9.1 0.043 14.5 6.0 1.8 2 0 0 2 2 2 0 Occludin homology domain HTH_38 PF13936.6 CP007180_00027 - 0.2 11.5 1.5 22 4.9 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Pox_A_type_inc PF04508.12 CP007180_00027 - 6.5 6.8 6.9 0.97 9.4 2.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TrbC PF04956.13 CP007180_00029 - 1.5e-14 54.0 8.5 1.6e-14 53.9 8.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP007180_00029 - 0.056 13.3 4.3 0.073 12.9 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) VirB3 PF05101.13 CP007180_00030 - 2e-13 50.4 1.9 2.1e-13 50.3 1.9 1.0 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein CagE_TrbE_VirB PF03135.14 CP007180_00031 - 3.7e-51 174.2 0.6 8.4e-51 173.0 0.6 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system HNOBA PF07701.14 CP007180_00031 - 0.039 13.4 0.1 0.085 12.3 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 CP007180_00032 - 3.1e-31 107.8 0.1 5e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) FapA PF03961.13 CP007180_00033 - 0.0039 15.9 6.9 0.0039 15.9 6.9 1.6 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 CP007180_00033 - 0.028 14.3 4.0 0.028 14.3 4.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Fib_alpha PF08702.10 CP007180_00033 - 0.6 10.3 12.2 0.061 13.5 4.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CP007180_00033 - 1.7 8.4 11.6 0.92 9.3 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator Striatin PF08232.12 CP007180_00033 - 4.6 7.8 9.6 14 6.2 9.6 1.9 1 1 0 1 1 1 0 Striatin family Syntaxin-6_N PF09177.11 CP007180_00033 - 9.3 6.9 10.2 1.8 9.2 4.5 2.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal SSB PF00436.25 CP007180_00035 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP007180_00036 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP007180_00036 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP007180_00036 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP007180_00036 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP007180_00037 - 3.9e-12 47.0 0.4 4.8e-12 46.7 0.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins GldM_N PF12081.8 CP007180_00037 - 0.033 14.3 0.5 0.054 13.6 0.5 1.4 1 0 0 1 1 1 0 GldM N-terminal domain T4SS PF07996.11 CP007180_00038 - 3.3e-10 40.7 11.1 3.8e-10 40.5 11.1 1.0 1 0 0 1 1 1 1 Type IV secretion system proteins AATF-Che1 PF13339.6 CP007180_00038 - 0.0044 17.7 2.4 0.0052 17.5 2.4 1.1 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DHR10 PF18595.1 CP007180_00038 - 0.023 14.7 5.2 0.031 14.3 5.2 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 CP007180_00038 - 0.032 14.9 0.6 0.032 14.9 0.6 2.0 1 1 0 2 2 2 0 Occludin homology domain VWA_2 PF13519.6 CP007180_00038 - 0.067 13.8 1.1 0.1 13.3 0.8 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain Snapin_Pallidin PF14712.6 CP007180_00038 - 0.1 13.0 5.1 0.28 11.6 5.1 1.8 1 1 0 1 1 1 0 Snapin/Pallidin TrbL PF04610.14 CP007180_00039 - 8.7e-32 110.6 33.1 8.7e-32 110.6 33.1 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP007180_00039 - 0.029 14.2 1.4 0.055 13.3 0.1 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 CP007180_00040 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 CP007180_00040 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 CP007180_00040 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP007180_00041 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP007180_00041 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP007180_00042 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 CP007180_00042 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 CP007180_00042 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 CP007180_00043 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP007180_00043 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP007180_00044 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP007180_00044 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP007180_00044 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP007180_00044 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP007180_00044 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP007180_00044 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CP007180_00044 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CP007180_00044 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP007180_00044 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP007180_00044 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP007180_00044 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP007180_00044 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 CP007180_00044 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CP007180_00044 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 CP007180_00044 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 CP007180_00044 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CP007180_00044 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CP007180_00044 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 CP007180_00044 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 CP007180_00044 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP007180_00044 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 CP007180_00044 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 CP007180_00044 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP007180_00044 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP007180_00044 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP007180_00044 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP007180_00044 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP007180_00044 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CP007180_00044 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 CP007180_00044 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP007180_00044 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP007180_00044 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP007180_00045 - 1e-105 354.3 0.1 1.4e-105 353.8 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP007180_00045 - 1.1e-24 86.8 0.0 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP007180_00045 - 6.5e-16 58.2 0.0 1.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 CP007180_00045 - 0.2 11.7 0.2 0.34 10.9 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 CP007180_00046 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP007180_00046 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 CP007180_00047 - 1.1e-36 126.1 1.8 1.3e-36 125.8 1.8 1.0 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP007180_00048 - 0.03 14.1 2.2 0.033 14.0 0.3 2.0 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 CP007180_00048 - 2.4 7.9 10.1 5 6.9 8.4 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NdhM PF10664.9 CP007180_00048 - 2.5 8.4 6.1 57 4.0 0.3 3.2 2 1 1 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M IFT20 PF14931.6 CP007180_00048 - 4.8 7.4 10.0 1.3 9.2 0.8 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Mod_r PF07200.13 CP007180_00048 - 8.2 6.5 12.0 85 3.2 9.1 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CdhD PF03599.16 CP007180_00049 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 CP007180_00049 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 CP007180_00049 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 CP007180_00050 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 CP007180_00051 - 9e-97 324.7 8.0 1.3e-96 324.2 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP007180_00051 - 9.7e-12 45.0 0.1 9.7e-12 45.0 0.1 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP007180_00051 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP007180_00051 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP007180_00051 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP007180_00051 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP007180_00051 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 CP007180_00051 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 CP007180_00051 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP007180_00051 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 CP007180_00051 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP007180_00051 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP007180_00051 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP007180_00051 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP007180_00051 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP007180_00051 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP007180_00051 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP007180_00053 - 3.9e-05 23.6 2.2 0.0001 22.2 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP007180_00053 - 0.02 14.9 4.4 0.16 11.9 4.4 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 CP007180_00055 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP007180_00055 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP007180_00055 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP007180_00055 - 3e-12 46.4 0.1 6.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP007180_00055 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP007180_00055 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP007180_00055 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP007180_00055 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP007180_00055 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family TrbC PF04956.13 CP007750_00002 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP007750_00002 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP007750_00004 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP007750_00004 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 CP007750_00005 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP007750_00005 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP007750_00005 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP007750_00005 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 CP007750_00006 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP007750_00006 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP007750_00006 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 CP007750_00006 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CP007750_00006 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP007750_00006 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 CP007750_00006 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 CP007750_00007 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CP007750_00008 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 CP007750_00008 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 CP007750_00008 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 CP007750_00009 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 CP007750_00009 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 CP007750_00009 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 CP007750_00009 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 CP007750_00010 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP007750_00010 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 CP007750_00011 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP007750_00011 - 0.074 13.0 0.3 0.33 10.9 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP007750_00011 - 0.13 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP007750_00011 - 0.27 11.9 5.3 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 CP007750_00012 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) CdvA PF18822.1 CP007750_00014 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 CP007750_00014 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 CP007750_00014 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CP007750_00015 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP007750_00015 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP007750_00015 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP007750_00015 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP007750_00015 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 CP007750_00016 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 CP007750_00017 - 9.3e-06 25.6 0.1 0.016 15.3 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CP007750_00017 - 9.6e-06 25.6 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CP007750_00017 - 0.00071 19.6 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CP007750_00017 - 0.0073 15.8 0.0 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CP007750_00017 - 0.0089 16.1 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP007750_00017 - 0.011 15.6 0.2 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 CP007750_00017 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CP007750_00017 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 CP007750_00017 - 0.065 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 CP007750_00017 - 0.073 12.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain NYN PF01936.18 CP007750_00018 - 1.1e-09 38.9 1.0 4.7e-09 36.9 1.0 2.0 1 1 0 1 1 1 1 NYN domain SNF2_N PF00176.23 CP007750_00019 - 1.7e-16 59.9 1.1 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP007750_00019 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP007750_00019 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP007750_00019 - 6.2e-06 26.1 1.6 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP007750_00019 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP007750_00020 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 CP007750_00021 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP007750_00021 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP007750_00021 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP007750_00021 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP007750_00021 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP007750_00022 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP007750_00022 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP007750_00023 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP007750_00023 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP007750_00023 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP007750_00023 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP007750_00023 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP007750_00024 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP007750_00024 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP007750_00024 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP007750_00024 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP007750_00024 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP007750_00024 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP007750_00024 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 CP007750_00025 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 CP007750_00026 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP007750_00026 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 CP007750_00027 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP007750_00027 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain DUF5442 PF17514.2 CP007750_00029 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) GTP_EFTU PF00009.27 CP007750_00030 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP007750_00030 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP007750_00030 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP007750_00030 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP007750_00030 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP007750_00030 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP007750_00030 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP007750_00030 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP007750_00030 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 CP007750_00032 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP007750_00032 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 CP007750_00033 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP007750_00033 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP007750_00033 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP007750_00033 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP007750_00033 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP007750_00033 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP007750_00033 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP007750_00033 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP007750_00033 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP007750_00033 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP007750_00033 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP007750_00033 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP007750_00033 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP007750_00033 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP007750_00033 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP007750_00033 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP007750_00033 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 CP007750_00034 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP007750_00036 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP007750_00036 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP007750_00036 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CP007750_00037 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP007750_00038 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP007750_00038 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP007750_00038 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP007750_00038 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CP007750_00039 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP007750_00039 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP007750_00039 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP007750_00039 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 CP007750_00040 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP007750_00040 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP007750_00040 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP007750_00040 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP007750_00040 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP007750_00040 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP007750_00040 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP007750_00040 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP007750_00040 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP007750_00040 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP007750_00040 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP007750_00040 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP007750_00040 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP007750_00040 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP007750_00040 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP007750_00040 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP007750_00040 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP007750_00040 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP007750_00040 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP007750_00040 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP007750_00040 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP007750_00040 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP007750_00040 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP007750_00040 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP007750_00040 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP007750_00040 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP007750_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP007750_00040 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP007750_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP007750_00040 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP007750_00040 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CP007750_00041 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP007750_00041 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CP007750_00042 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP007750_00042 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 CP007750_00043 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP007750_00043 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CP007750_00044 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP007750_00044 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CP007750_00045 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP007750_00045 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP007750_00045 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 CP007750_00046 - 1.6e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP007750_00046 - 0.0055 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP007750_00046 - 0.015 16.0 5.3 0.015 16.0 5.3 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 CP007750_00046 - 0.018 15.7 1.0 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 CP007750_00046 - 2.9 8.2 11.5 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 CP007750_00046 - 5.1 7.2 14.8 0.55 10.3 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 CP007750_00047 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP007750_00047 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP007750_00047 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP007750_00047 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CP007750_00048 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 CP007750_00049 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP007750_00049 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP007750_00049 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP007750_00049 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP007750_00049 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP007750_00049 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 CP007750_00050 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP007750_00050 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP007750_00050 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP007750_00050 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP007750_00050 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 CP007750_00051 - 1.6e-28 100.2 0.0 4.5e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system HNOBA PF07701.14 CP007750_00051 - 0.022 14.2 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 CP007750_00051 - 0.2 11.6 0.0 0.54 10.2 0.0 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like TraC_F_IV PF11130.8 CP009044_00001 - 7.6e-30 104.3 0.0 1.4e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 CP009044_00001 - 3.3e-10 39.4 0.0 1.7e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 CP009044_00001 - 0.00074 18.5 0.0 0.8 8.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 CP009044_00001 - 0.0072 16.6 0.1 4.1 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zot PF05707.12 CP009044_00001 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) FH2 PF02181.23 CP009044_00001 - 0.016 14.4 1.1 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain CbiA PF01656.23 CP009044_00001 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0181 PF03701.14 CP009044_00001 - 0.22 11.2 0.5 0.67 9.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) TrbI_Ftype PF09677.10 CP009044_00002 - 2.1e-05 24.8 1.3 2.5e-05 24.6 1.3 1.4 1 1 0 1 1 1 1 Type-F conjugative transfer system protein (TrbI_Ftype) Peptidase_S26 PF10502.9 CP009044_00003 - 2.2e-13 50.2 0.0 3.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 TraH PF06122.11 CP009044_00004 - 5.6e-68 229.8 2.0 7.8e-68 229.4 2.0 1.2 1 0 0 1 1 1 1 Conjugative relaxosome accessory transposon protein TraN PF06986.11 CP009044_00006 - 4.3e-29 101.9 9.8 4.3e-29 101.9 9.8 4.9 2 2 3 5 5 5 2 Type-1V conjugative transfer system mating pair stabilisation Staphylokinase PF02821.16 CP009044_00011 - 0.075 13.5 5.2 2.6 8.5 1.5 2.1 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family HTH_19 PF12844.7 CP009044_00013 - 9.4e-08 32.0 0.6 3.6e-07 30.1 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 CP009044_00013 - 3.1e-06 27.1 0.2 5.9e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 CP009044_00013 - 0.0061 17.0 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Phage_CI_repr PF07022.13 CP009044_00013 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_25 PF13413.6 CP009044_00013 - 0.014 15.2 0.0 0.028 14.3 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Pup PF05639.11 CP009044_00013 - 0.02 15.8 0.3 0.038 14.9 0.3 1.4 1 0 0 1 1 1 0 Pup-like protein Nbl1_Borealin_N PF10444.9 CP009044_00013 - 0.047 13.3 2.8 0.37 10.5 0.2 2.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF16 PF01519.16 CP009044_00013 - 0.16 12.5 3.8 0.41 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-ACC PF17848.1 CP009044_00016 - 0.0036 17.3 4.1 0.8 9.8 0.4 2.6 2 0 0 2 2 2 2 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 CP009044_00016 - 0.0069 15.8 2.9 1.8 8.1 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 CP009044_00016 - 0.0087 15.6 2.4 0.77 9.3 0.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding tRNA-synt_1g PF09334.11 CP009044_00016 - 0.021 13.6 0.7 0.024 13.4 0.7 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-ISL3 PF14690.6 CP009044_00016 - 0.023 15.4 1.2 0.26 12.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 CP009044_00016 - 0.031 14.4 0.3 5.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.6 CP009044_00016 - 0.032 14.0 1.0 6.4 6.6 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-LITAF-like PF10601.9 CP009044_00016 - 0.064 13.5 1.4 7.3 6.9 0.0 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Elf1 PF05129.13 CP009044_00016 - 0.09 12.8 2.1 0.075 13.1 0.9 1.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.6 CP009044_00016 - 0.09 13.7 1.8 19 6.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3 PF13878.6 CP009044_00016 - 0.1 12.4 1.6 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF4379 PF14311.6 CP009044_00016 - 0.13 12.6 6.2 0.49 10.8 1.4 2.6 2 1 0 2 2 2 0 Probable Zinc-ribbon domain DUF35_N PF12172.8 CP009044_00016 - 0.18 11.7 2.4 5.2 7.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 CP009044_00016 - 0.22 11.3 4.3 8.6 6.2 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 CP009044_00016 - 0.25 11.3 4.7 7 6.7 0.2 2.3 1 1 1 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 CP009044_00016 - 0.25 11.4 2.4 1.2 9.2 2.4 1.9 1 1 0 1 1 1 0 CpXC protein Zn_Tnp_IS91 PF14319.6 CP009044_00016 - 0.36 10.9 4.1 1 9.4 0.4 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CP009044_00016 - 0.66 10.0 5.5 5.1 7.1 3.1 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Phage_integrase PF00589.22 CP009044_00017 - 4.8e-23 81.8 0.1 8.8e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 CP009044_00017 - 0.0021 18.5 8.6 0.2 12.1 0.7 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 CP009044_00017 - 0.0042 17.4 0.3 0.023 15.0 0.3 2.2 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain TSNAXIP1_N PF15739.5 CP009044_00017 - 0.11 12.8 1.6 0.29 11.5 1.3 1.8 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Phage_int_SAM_3 PF14659.6 CP009044_00017 - 0.99 9.7 6.9 0.67 10.3 0.7 3.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF1566 PF07603.11 CP009044_00018 - 0.0015 18.9 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) DUF433 PF04255.14 CP009044_00019 - 0.047 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Toxin_YhaV PF11663.8 CP009044_00019 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system WGR PF05406.15 CP009044_00023 - 6.7e-07 29.3 0.3 8.8e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 WGR domain DUF3951 PF13131.6 CP009044_00027 - 0.048 13.9 0.2 0.048 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF4064 PF13273.6 CP009044_00028 - 1.1 9.6 10.9 2.4e+02 2.1 10.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2929 PF11151.8 CP009044_00028 - 2.9 8.3 8.4 0.12 12.7 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2929) HD_2 PF12917.7 CP009044_00029 - 0.00032 20.5 0.1 0.00069 19.4 0.1 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme CDT1 PF08839.11 CP009044_00031 - 0.089 13.1 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like DUF1351 PF07083.11 CP009044_00032 - 3.8e-24 85.6 8.0 3.8e-24 85.6 8.0 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1351) DUF4337 PF14235.6 CP009044_00032 - 0.96 9.5 5.4 2.1 8.4 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Allexi_40kDa PF05549.11 CP009044_00032 - 1.6 8.2 6.9 0.15 11.5 1.9 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein KIP1 PF07765.12 CP009044_00032 - 8.7 6.5 9.0 0.72 10.0 1.3 2.5 2 0 0 2 2 2 0 KIP1-like protein LBR_tudor PF09465.10 CP009044_00033 - 0.036 13.9 0.2 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain zf-B_box PF00643.24 CP009044_00034 - 0.006 16.7 13.5 0.0062 16.7 7.5 2.3 2 0 0 2 2 2 1 B-box zinc finger FYVE PF01363.21 CP009044_00034 - 0.026 14.6 6.7 0.067 13.3 6.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger DUF4428 PF14471.6 CP009044_00034 - 0.069 13.1 0.1 0.069 13.1 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.13 CP009044_00034 - 0.19 11.6 12.5 1.7 8.6 1.0 2.4 2 0 0 2 2 2 0 ClpX C4-type zinc finger Gin PF10764.9 CP009044_00034 - 0.24 11.4 10.0 3.5 7.7 0.2 2.7 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_2 PF13639.6 CP009044_00034 - 0.34 11.3 9.3 7.6 7.0 7.4 2.4 1 1 1 2 2 2 0 Ring finger domain zf-CHY PF05495.12 CP009044_00034 - 0.35 11.4 10.0 0.22 12.0 1.4 2.3 1 1 1 2 2 2 0 CHY zinc finger Ac81 PF05820.11 CP009044_00034 - 0.92 9.0 4.8 3.3 7.2 2.3 2.1 2 0 0 2 2 2 0 Baculoviridae AC81 zf-C3HC4_3 PF13920.6 CP009044_00034 - 1.2 9.0 10.5 9.4 6.2 5.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CP009044_00034 - 1.5 8.7 13.2 2.1 8.2 6.1 2.5 1 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Tnp_zf-ribbon_2 PF13842.6 CP009044_00034 - 8.2 7.3 10.6 2.7 8.8 5.2 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-ACC PF17848.1 CP009044_00037 - 0.098 12.8 3.8 8 6.6 0.5 3.0 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 CP009044_00037 - 6.7 6.8 10.9 31 4.7 10.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Toprim_2 PF13155.6 CP009044_00039 - 1e-14 54.7 0.0 2.7e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Toprim-like Toprim_3 PF13362.6 CP009044_00039 - 1.6e-08 34.8 0.0 3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.20 CP009044_00039 - 4.3e-07 29.7 0.3 9.7e-07 28.5 0.3 1.6 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_4 PF13662.6 CP009044_00039 - 0.0096 16.4 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF3854 PF12965.7 CP009044_00039 - 0.023 14.7 0.2 0.29 11.1 0.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) N6_N4_Mtase PF01555.18 CP009044_00040 - 2.4e-05 24.2 0.4 0.042 13.5 0.2 2.1 2 0 0 2 2 2 2 DNA methylase DpnI_C PF17726.1 CP009044_00040 - 0.00013 22.0 0.3 0.00036 20.6 0.3 1.7 1 0 0 1 1 1 1 Dam-replacing HTH domain zf-BED PF02892.15 CP009044_00041 - 0.042 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 BED zinc finger DUF4258 PF14076.6 CP009044_00045 - 0.069 13.5 0.3 0.81 10.1 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) Methyltransf_23 PF13489.6 CP009044_00045 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MPTase-PolyVal PF18818.1 CP009044_00046 - 8.2e-48 161.6 0.0 1.2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase superfamily domain DUF1738 PF08401.11 CP009044_00046 - 1.1e-33 116.1 0.1 1.9e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) EpmC PF04315.12 CP009044_00046 - 0.00047 19.9 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P hydroxylase Tox-MPTase3 PF15639.6 CP009044_00046 - 0.0042 16.9 0.1 0.0092 15.8 0.1 1.5 1 0 0 1 1 1 1 Metallopeptidase toxin 3 DUF4127 PF13552.6 CP009044_00046 - 0.021 13.5 0.1 0.028 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) GP88 PF17338.2 CP009044_00046 - 0.022 14.2 0.1 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 Gene product 88 Fucose_iso_N2 PF07882.12 CP009044_00047 - 0.0057 16.2 0.8 0.01 15.5 0.3 1.6 1 1 1 2 2 2 1 L-fucose isomerase, second N-terminal domain RNA_pol_Rpb8 PF03870.15 CP009044_00047 - 0.056 13.6 0.1 0.076 13.2 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb8 s48_45 PF07422.13 CP009044_00047 - 0.082 13.5 0.8 0.28 11.8 0.1 1.8 1 1 0 2 2 2 0 Sexual stage antigen s48/45 domain RecT PF03837.14 CP009044_00048 - 1.2e-36 126.1 0.3 4.5e-36 124.2 0.0 1.8 1 1 1 2 2 2 1 RecT family Cas_Cas4 PF01930.17 CP009044_00051 - 1.6e-06 28.3 0.2 1.6e-06 28.3 0.2 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 CP009044_00051 - 8.1e-05 22.7 1.2 0.00013 22.0 0.2 1.9 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Nsp1_C PF05064.13 CP009044_00051 - 0.0026 17.5 0.5 0.0026 17.5 0.5 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region GrpE PF01025.19 CP009044_00051 - 0.011 15.4 1.7 0.011 15.4 1.7 2.3 2 0 0 2 2 2 0 GrpE CENP-F_leu_zip PF10473.9 CP009044_00051 - 0.035 14.1 9.6 0.043 13.8 3.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 CP009044_00051 - 0.058 12.7 1.6 0.1 11.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CdvA PF18822.1 CP009044_00051 - 0.2 11.5 8.1 1.2 8.9 1.2 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF615 PF04751.14 CP009044_00051 - 1.7 8.6 7.9 0.17 11.8 1.5 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF615) CHASE3 PF05227.13 CP009044_00051 - 6.7 6.6 8.3 1.5 8.7 0.7 2.7 3 0 0 3 3 3 0 CHASE3 domain SSB PF00436.25 CP009044_00053 - 1.8e-29 101.9 0.2 3.2e-29 101.0 0.2 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Pex14_N PF04695.13 CP009044_00053 - 0.29 11.8 7.3 0.46 11.1 7.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Toxin-JAB1 PF15659.6 CP009044_00054 - 0.088 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 JAB-like toxin 1 Dus PF01207.17 CP009044_00058 - 0.03 13.4 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) SLT PF01464.20 CP009044_00059 - 4.6e-19 68.2 0.0 6.1e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 CP009044_00059 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family DUF480 PF04337.12 CP009044_00060 - 0.0017 18.4 0.1 0.0019 18.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF480 RdRP_1 PF00680.20 CP009044_00060 - 0.027 13.0 0.1 0.03 12.8 0.1 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF3267 PF11667.8 CP009044_00061 - 0.042 14.1 8.6 0.053 13.8 5.1 2.6 1 1 1 2 2 2 0 Putative zincin peptidase Peptidase_M50B PF13398.6 CP009044_00061 - 0.14 11.8 7.8 2.4 7.7 7.7 2.3 1 1 0 1 1 1 0 Peptidase M50B-like GGDEF PF00990.21 CP009044_00062 - 5e-34 117.4 0.6 1.1e-33 116.2 0.6 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HD PF01966.22 CP009044_00062 - 2.7e-05 24.4 0.4 2.7e-05 24.4 0.4 3.0 4 0 0 4 4 4 1 HD domain SporV_AA PF12164.8 CP009044_00062 - 0.039 14.3 4.1 0.057 13.8 0.2 3.1 3 0 0 3 3 3 0 Stage V sporulation protein AA STAR_dimer PF16544.5 CP009044_00062 - 0.044 13.4 0.3 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Toxin-deaminase PF14424.6 CP009044_00062 - 0.045 13.9 0.6 0.045 13.9 0.6 3.2 3 0 0 3 3 3 0 The BURPS668_1122 family of deaminases Stealth_CR4 PF17103.5 CP009044_00062 - 0.081 12.8 0.1 6.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 SurA_N_2 PF13623.6 CP009044_00062 - 4.1 7.3 12.7 2.3 8.1 0.5 3.8 4 0 0 4 4 4 0 SurA N-terminal domain TrwB_AAD_bind PF10412.9 CP009044_00063 - 5.1e-16 58.6 0.0 1.7e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 CP009044_00063 - 2e-11 43.4 0.6 2.8e-11 42.9 0.6 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP009044_00063 - 4.3e-10 39.7 0.0 8.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG DUF87 PF01935.17 CP009044_00063 - 0.0005 20.2 0.3 0.0045 17.1 0.3 2.3 1 1 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 CP009044_00063 - 0.0014 17.9 0.0 0.0035 16.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 CP009044_00063 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 CP009044_00063 - 0.0022 18.0 0.0 0.01 15.8 0.0 2.1 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea DUF853 PF05872.12 CP009044_00063 - 0.0045 15.6 0.0 0.0082 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_10 PF12846.7 CP009044_00063 - 0.0054 15.7 0.1 0.12 11.2 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.6 CP009044_00063 - 0.011 16.1 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CP009044_00063 - 0.095 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 CP009044_00063 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain HD_5 PF13487.6 CP009044_00064 - 4.6e-06 26.8 0.0 8.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 HD domain CLP_protease PF00574.23 CP009044_00066 - 0.15 12.0 0.3 0.3 10.9 0.3 1.5 1 0 0 1 1 1 0 Clp protease GA-like PF17573.2 CP009044_00067 - 0.035 14.0 0.4 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 GA-like domain Orthopox_A49R PF06489.11 CP009044_00067 - 0.16 12.2 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A49R protein HTH_3 PF01381.22 CP009044_00068 - 2.7e-14 52.9 0.0 3.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CP009044_00068 - 7.9e-13 48.2 0.0 8.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CP009044_00068 - 8.3e-08 32.5 0.0 8.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 CP009044_00068 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_CI_repr PF07022.13 CP009044_00068 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.3 1 1 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain Pou PF00157.17 CP009044_00068 - 0.026 14.5 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_37 PF13744.6 CP009044_00068 - 0.047 13.7 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 CP009044_00068 - 0.055 13.6 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_23 PF13384.6 CP009044_00068 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain WYL_3 PF18488.1 CP009044_00068 - 0.081 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 WYL domain YdaS_antitoxin PF15943.5 CP009044_00068 - 0.1 12.4 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SNase PF00565.17 CP009044_00069 - 4.4e-17 62.5 0.1 5.5e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue AAA_25 PF13481.6 CP009044_00072 - 5.9e-17 61.9 0.0 9.6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB PF00772.21 CP009044_00072 - 1.3e-06 28.4 0.3 2.9e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain Thioredoxin_2 PF13098.6 CP009044_00073 - 2.7e-05 24.6 0.2 0.00022 21.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CP009044_00073 - 3.2e-05 24.0 0.0 4.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 CP009044_00073 - 0.00012 22.1 0.1 0.0003 20.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF255 VSG_B PF13206.6 CP009044_00074 - 0.018 14.3 0.9 0.018 14.3 0.9 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain HSCB_C PF07743.13 CP009044_00074 - 0.019 15.5 2.0 0.021 15.3 2.0 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain YtxH PF12732.7 CP009044_00074 - 0.034 14.7 0.1 0.045 14.3 0.1 1.2 1 0 0 1 1 1 0 YtxH-like protein TrbC_Ftype PF09673.10 CP009044_00075 - 9.3e-17 61.1 0.0 2.2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein DUF3388 PF11868.8 CP009044_00075 - 0.035 13.4 0.2 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) EAL PF00563.20 CP009044_00076 - 3.4e-28 98.8 0.0 4.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 EAL domain TraU PF06834.11 CP009044_00077 - 8.2e-100 334.0 0.4 9.4e-100 333.8 0.4 1.0 1 0 0 1 1 1 1 TraU protein TraF PF13728.6 CP009044_00079 - 3e-30 105.7 10.7 3.5e-30 105.5 10.7 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein KaiB PF07689.12 CP009044_00079 - 0.055 13.2 0.2 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 KaiB domain ASC PF00858.24 CP009044_00079 - 0.72 8.7 5.6 0.91 8.4 5.6 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TraG_N PF07916.11 CP009044_00080 - 1.7e-51 175.6 17.8 1.7e-51 175.6 17.8 2.8 3 0 0 3 3 3 1 TraG-like protein, N-terminal region CdiI_2 PF18593.1 CP009044_00080 - 0.18 12.5 0.8 11 6.7 0.4 2.9 1 1 1 2 2 2 0 CdiI immunity protein YfhO PF09586.10 CP009044_00081 - 0.016 13.5 2.6 0.018 13.3 2.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1189 PF06691.11 CP009044_00081 - 0.017 14.7 2.0 0.02 14.5 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) Herpes_LMP1 PF05297.11 CP009044_00081 - 0.068 12.4 3.2 0.083 12.1 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RHH_3 PF12651.7 CP009044_00082 - 0.0013 18.6 1.3 0.0028 17.6 0.8 1.8 2 0 0 2 2 2 1 Ribbon-helix-helix domain DUF5123 PF17161.4 CP009044_00082 - 0.058 14.5 0.9 0.068 14.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5123) UvrB_inter PF17757.1 CP009044_00083 - 0.052 13.7 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 UvrB interaction domain ALP_N PF17989.1 CP009044_00085 - 5.9e-15 55.7 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Actin like proteins N terminal domain FtsA PF14450.6 CP009044_00085 - 0.00012 22.5 0.1 0.031 14.7 0.0 2.4 2 0 0 2 2 2 2 Cell division protein FtsA DUF2800 PF10926.8 CP009044_00085 - 0.12 11.6 0.1 0.37 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) DBR1 PF05011.13 CP009044_00086 - 0.0072 16.8 1.1 0.0081 16.6 1.1 1.1 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain DUF3400 PF11880.8 CP009044_00087 - 0.1 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) DUF2786 PF10979.8 CP009044_00087 - 0.18 11.8 1.3 0.37 10.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Acetyltransf_9 PF13527.7 CP009044_00088 - 0.099 12.7 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ring_hydroxyl_B PF00866.18 CP009044_00089 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit SSXT PF05030.12 CP009044_00090 - 0.022 14.4 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) NMT PF01233.19 CP009044_00090 - 0.092 12.6 0.6 0.11 12.3 0.6 1.5 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain bZIP_2 PF07716.15 CP009044_00090 - 0.13 12.4 0.3 0.13 12.4 0.3 1.6 2 0 0 2 2 2 0 Basic region leucine zipper BfiI_DBD PF18243.1 CP009044_00090 - 0.17 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain AbiH PF14253.6 CP009044_00092 - 0.023 14.6 1.3 0.03 14.2 1.3 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH PH_12 PF16457.5 CP009044_00092 - 0.1 13.1 0.2 0.83 10.2 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain ANT PF03374.14 CP009044_00093 - 0.041 14.2 0.0 0.045 14.1 0.0 1.1 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain PhetRS_B1 PF18262.1 CP009044_00093 - 0.062 13.5 0.2 0.076 13.2 0.2 1.1 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain HTH_28 PF13518.6 CP009044_00093 - 0.1 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TMEM51 PF15345.6 CP009044_00094 - 0.11 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_19 PF13245.6 CP009044_00095 - 2.8e-13 50.4 0.0 7.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CP009044_00095 - 4.2e-13 49.5 7.9 3.8e-08 33.2 2.3 3.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CP009044_00095 - 3.2e-12 46.5 2.8 1.2e-11 44.7 1.9 2.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 CP009044_00095 - 5.1e-09 35.8 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CP009044_00095 - 1.1e-08 35.1 0.7 0.0055 16.5 0.0 3.5 2 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CP009044_00095 - 0.00014 21.6 0.1 0.0023 17.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 CP009044_00095 - 0.00093 18.7 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 CP009044_00095 - 0.011 15.7 5.8 0.027 14.5 1.5 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CP009044_00095 - 0.017 15.0 0.3 6.1 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain OMPdecase PF00215.24 CP009044_00095 - 0.11 12.1 0.1 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family RNase_T PF00929.24 CP009044_00097 - 0.036 14.6 0.1 0.04 14.4 0.1 1.1 1 0 0 1 1 1 0 Exonuclease DUF1722 PF08349.11 CP009044_00098 - 0.11 12.8 0.0 0.13 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF460 PF04312.13 CP009044_00100 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF5643 PF18705.1 CP009044_00103 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5643) MrpF_PhaF PF04066.13 CP009044_00106 - 0.01 16.2 1.3 0.01 16.2 1.3 2.5 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) UPF0242 PF06785.11 CP009044_00106 - 0.026 14.6 1.1 0.028 14.5 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UPF0016 PF01169.19 CP009044_00106 - 0.039 14.3 7.1 0.089 13.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein family UPF0016 TrbC PF04956.13 CP009044_00106 - 1.2 9.4 11.4 1.3 9.3 11.4 1.0 1 0 0 1 1 1 0 TrbC/VIRB2 family TraL PF07178.11 CP009044_00107 - 2.4e-12 47.2 1.0 2.7e-12 47.0 1.0 1.1 1 0 0 1 1 1 1 TraL protein ThrE PF06738.12 CP009044_00107 - 0.024 14.0 0.3 0.026 13.9 0.3 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter TraE PF05309.11 CP009044_00108 - 2e-34 118.5 1.7 2.5e-34 118.3 1.7 1.0 1 0 0 1 1 1 1 TraE protein MadM PF03818.13 CP009044_00108 - 0.047 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit TraK PF06586.11 CP009044_00109 - 9.5e-24 84.4 3.7 3.6e-23 82.5 3.7 1.7 1 1 0 1 1 1 1 TraK protein NusG_II PF07009.11 CP009044_00109 - 0.32 11.2 4.5 0.13 12.4 0.6 2.2 2 1 0 2 2 2 0 NusG domain II TrbI PF03743.14 CP009044_00110 - 3.5e-33 115.0 1.1 4.8e-33 114.6 1.1 1.2 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein Bap31_Bap29_C PF18035.1 CP009044_00110 - 0.0036 17.3 1.3 0.011 15.7 1.3 1.8 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 CP009044_00110 - 0.0052 17.0 2.6 0.01 16.0 2.6 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 CP009044_00110 - 0.0093 16.1 2.9 0.027 14.6 2.9 1.8 1 0 0 1 1 1 1 bZIP transcription factor UPF0242 PF06785.11 CP009044_00110 - 0.046 13.8 1.5 0.083 13.0 1.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 CP009044_00110 - 0.094 12.5 3.1 0.23 11.2 3.1 1.6 1 0 0 1 1 1 0 Septum formation initiator FAD-SLDH PF12318.8 CP009044_00110 - 0.13 12.3 0.8 0.26 11.3 0.2 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase YabA PF06156.13 CP009044_00110 - 0.19 12.4 1.5 0.48 11.1 1.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Thioredoxin_2 PF13098.6 CP009044_00111 - 3.3e-16 59.7 0.1 6.6e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 CP009044_00111 - 1.3e-07 30.9 0.1 3e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 CP009044_00111 - 1.3e-06 28.7 2.0 0.0038 17.4 0.3 3.2 1 1 1 2 2 2 2 Thioredoxin DSBA PF01323.20 CP009044_00111 - 1.3e-06 28.3 0.3 0.01 15.6 0.1 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 CP009044_00111 - 0.0039 17.4 0.3 0.038 14.2 0.1 2.4 2 0 0 2 2 2 1 Glutaredoxin ATPgrasp_YheCD PF14398.6 CP009044_00111 - 0.0088 15.3 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp TraF PF13728.6 CP009044_00111 - 0.013 15.3 0.1 6.2 6.6 0.0 2.4 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CP009044_00111 - 0.021 14.9 1.1 9.8 6.3 0.4 2.8 2 1 1 3 3 3 0 Thioredoxin domain Thioredoxin_8 PF13905.6 CP009044_00111 - 0.04 14.2 0.4 0.18 12.1 0.4 2.1 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.6 CP009044_00111 - 0.071 12.8 0.4 6.9 6.3 0.4 2.3 1 1 1 2 2 2 0 Thioredoxin TraV PF09676.10 CP009044_00112 - 0.0043 18.0 5.3 0.0097 16.9 5.2 1.8 1 1 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) SH3_4 PF06347.13 CP009044_00112 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_3 PF08239.11 CP009044_00112 - 0.013 15.7 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Transketolase_N PF00456.21 CP009044_00112 - 0.049 12.6 0.3 0.085 11.8 0.3 1.5 1 1 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Herpes_glycop_D PF01537.17 CP009044_00112 - 0.052 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain SH3_3 PF08239.11 CP009044_00113 - 5.6e-05 23.3 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain ADIP PF11559.8 CP009044_00113 - 0.0013 18.8 3.7 0.0023 18.0 3.7 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 CP009044_00113 - 0.0038 17.1 1.5 0.0054 16.6 1.5 1.3 1 0 0 1 1 1 1 Sec34-like family CLZ PF16526.5 CP009044_00113 - 0.0068 16.7 4.4 1.8 9.0 0.0 2.4 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SMC_ScpB PF04079.16 CP009044_00113 - 0.0085 15.7 1.4 0.013 15.2 1.4 1.3 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB V_ATPase_I PF01496.19 CP009044_00113 - 0.022 12.7 3.4 0.025 12.5 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 CP009044_00113 - 0.03 14.7 0.6 0.045 14.1 0.6 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Cob_adeno_trans PF01923.18 CP009044_00113 - 0.041 14.0 1.6 0.067 13.3 1.6 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Spectrin PF00435.21 CP009044_00113 - 0.046 14.2 2.7 0.11 13.0 2.7 1.6 1 0 0 1 1 1 0 Spectrin repeat M PF02370.16 CP009044_00113 - 0.072 13.7 6.6 0.31 11.7 6.6 2.2 1 0 0 1 1 1 0 M protein repeat DUF1319 PF07028.11 CP009044_00113 - 0.11 12.7 3.3 0.23 11.7 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) TolA_bind_tri PF16331.5 CP009044_00113 - 0.16 12.0 2.2 0.53 10.4 1.7 2.0 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF272 PF03312.15 CP009044_00113 - 0.2 11.9 3.6 1.6 9.0 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF272) FlaC_arch PF05377.11 CP009044_00113 - 0.24 11.8 4.0 2 8.9 1.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 CP009044_00113 - 0.27 11.7 2.6 0.55 10.7 1.7 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 CP009044_00113 - 0.67 9.9 6.4 0.83 9.6 3.3 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 CP009044_00113 - 1.6 9.4 7.4 2.7 8.7 7.4 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Swi5 PF07061.11 CP009044_00113 - 5.2 7.2 8.9 1.3 9.1 3.1 2.5 2 1 1 3 3 3 0 Swi5 Peptidase_C39 PF03412.15 CP010073_00002 - 9e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 CP010073_00002 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 CP010073_00002 - 0.085 13.4 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family Relaxase PF03432.14 CP010073_00004 - 1.6e-09 37.8 6.2 1.6e-09 37.8 6.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP010073_00005 - 0.00011 22.1 5.7 0.067 13.2 0.7 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP010073_00005 - 0.049 13.8 1.8 0.069 13.3 1.4 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP010073_00005 - 0.28 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP010073_00005 - 0.3 11.4 5.9 1.4 9.2 2.0 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP010073_00005 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 CP010073_00006 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 CP010073_00006 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 CP010073_00006 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 CP010073_00008 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 CP010073_00009 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP010073_00009 - 0.087 12.8 0.3 0.38 10.7 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP010073_00009 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP010073_00009 - 0.2 12.3 4.2 1.4 9.5 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP010073_00010 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) CCDC50_N PF15295.6 CP010073_00010 - 0.011 15.9 2.0 0.013 15.6 2.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus BAR_3 PF16746.5 CP010073_00010 - 0.021 14.6 1.6 0.023 14.4 1.6 1.0 1 0 0 1 1 1 0 BAR domain of APPL family Uteroglobin PF01099.17 CP010073_00010 - 2.4 8.6 5.7 12 6.3 0.7 2.2 1 1 1 2 2 2 0 Uteroglobin family Sdh_cyt PF01127.22 CP010073_00011 - 0.00091 19.3 0.8 0.0011 19.0 0.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 CP010073_00011 - 0.13 12.6 3.1 0.17 12.2 3.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2207 PF09972.9 CP010073_00011 - 0.58 8.9 2.2 0.6 8.8 2.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2633 PF11119.8 CP010073_00011 - 0.58 10.1 3.8 2.3 8.2 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP010073_00013 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP010073_00014 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP010073_00015 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP010073_00015 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP010073_00015 - 0.0022 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP010073_00015 - 0.0088 15.4 0.0 0.058 12.7 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP010073_00015 - 0.014 15.8 0.2 0.33 11.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP010073_00015 - 0.21 11.6 2.3 1.2 9.3 2.3 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP010073_00015 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 CP010073_00016 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP010073_00016 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP010073_00016 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 CP010073_00017 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 CP010073_00019 - 1.5e-14 54.0 8.5 1.6e-14 53.9 8.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP010073_00019 - 0.056 13.3 4.3 0.073 12.9 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP010073_00020 - 3.6e-49 167.7 0.3 9e-49 166.4 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP010073_00020 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP010073_00020 - 3.8e-07 29.4 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP010073_00020 - 0.024 14.7 4.5 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 CP010073_00021 - 6.9e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP010073_00021 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP010073_00021 - 0.031 13.9 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP010073_00021 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP010073_00021 - 0.56 10.3 5.4 7.7 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 Phage_pRha PF09669.10 CP010073_00022 - 4.3e-24 84.9 0.3 6.9e-24 84.2 0.3 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 CP010073_00023 - 0.075 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP010073_00023 - 0.15 10.6 14.4 0.009 14.7 7.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP010073_00023 - 0.95 9.6 11.6 0.062 13.5 3.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP010073_00023 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF465 PF04325.13 CP010073_00023 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 CP010073_00024 - 1.7e-25 89.0 0.1 2.2e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP010073_00025 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP010073_00025 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP010073_00025 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP010073_00025 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP010073_00026 - 5.7e-28 98.7 13.6 7.8e-28 98.2 13.6 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP010073_00026 - 0.0056 16.8 1.3 0.024 14.8 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP010073_00026 - 0.0092 16.7 6.0 0.0092 16.7 6.0 2.4 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 CP010073_00026 - 0.1 13.3 3.5 0.077 13.7 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 CP010073_00026 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 CP010073_00026 - 3.1 8.3 8.6 9.9 6.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 CP010073_00027 - 2.3e-30 106.0 31.8 2.3e-30 106.0 31.8 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP010073_00027 - 0.17 11.7 1.7 0.55 10.1 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP010073_00027 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP010073_00028 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP010073_00028 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP010073_00029 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP010073_00029 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP010073_00030 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP010073_00030 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP010073_00031 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP010073_00031 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP010073_00032 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP010073_00032 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP010073_00032 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP010073_00032 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP010073_00032 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP010073_00032 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP010073_00032 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP010073_00032 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP010073_00032 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP010073_00032 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP010073_00032 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP010073_00032 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP010073_00032 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP010073_00032 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP010073_00032 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP010073_00032 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP010073_00032 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP010073_00032 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP010073_00032 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP010073_00032 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP010073_00032 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP010073_00032 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP010073_00032 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP010073_00032 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP010073_00032 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP010073_00032 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP010073_00032 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP010073_00032 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP010073_00032 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP010073_00032 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP010073_00032 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP010073_00033 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP010073_00033 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP010073_00033 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP010073_00033 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP010073_00034 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP010073_00034 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP010073_00034 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP010073_00035 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP010073_00036 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP010073_00036 - 0.077 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP010073_00036 - 0.74 9.8 5.2 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP010073_00038 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP010073_00039 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP010073_00039 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP010073_00039 - 1.7e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP010073_00039 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP010073_00039 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP010073_00039 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CP010073_00039 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP010073_00039 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 CP010073_00039 - 0.088 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 CP010073_00039 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP010073_00039 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP010073_00039 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP010073_00039 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP010073_00039 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP010073_00039 - 6.9 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP010073_00039 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP010073_00040 - 2.7e-05 24.1 2.2 7.5e-05 22.6 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP010073_00040 - 0.016 15.2 4.6 0.14 12.1 4.6 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 CP010073_00042 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP010073_00042 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP010073_00042 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP010073_00042 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP010073_00042 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP010073_00042 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP010073_00042 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP010073_00042 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP010073_00042 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 CP010073_00043 - 1.5e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CP010073_00043 - 3.5e-06 27.0 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CP010073_00043 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 CP010073_00043 - 0.088 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication APH PF01636.23 CP010073_00044 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP010073_00044 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CP010073_00044 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 CP010073_00044 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 CP010073_00044 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 CP010073_00044 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 CP010073_00045 - 1.6e-24 87.2 0.0 2.1e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Lip_prot_lig_C PF10437.9 CP010073_00046 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP010073_00046 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 CP010073_00047 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 CP010073_00048 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP010073_00048 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP010073_00048 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP010073_00048 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP010073_00048 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP010073_00048 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP010073_00048 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 CP010073_00049 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP010073_00049 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP010073_00049 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP010073_00049 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP010073_00049 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP010073_00050 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP010073_00050 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP010073_00051 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP010073_00051 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP010073_00051 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP010073_00051 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP010073_00051 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP010073_00052 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP010073_00053 - 2e-16 59.6 0.8 6e-16 58.1 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP010073_00053 - 5.5e-08 33.0 8.4 5.5e-08 33.0 8.4 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP010073_00053 - 9.1e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP010073_00053 - 1.1e-05 25.3 1.8 0.0012 18.7 0.3 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP010073_00053 - 3.8e-05 24.1 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase HTH_3 PF01381.22 CP010073_00054 - 4.7e-06 26.6 0.0 0.00046 20.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 CP010073_00054 - 1.1e-05 25.3 0.2 0.011 15.7 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain Phage_CI_repr PF07022.13 CP010073_00054 - 0.00047 20.2 0.0 0.081 13.0 0.0 2.5 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_23 PF13384.6 CP010073_00054 - 0.0075 16.0 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 CP010073_00054 - 0.0076 15.8 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CP010073_00054 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP010073_00054 - 0.022 14.6 0.1 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_26 PF13443.6 CP010073_00054 - 0.045 14.2 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 CP010073_00054 - 0.1 12.8 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 CP010073_00054 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_AlpA PF05930.12 CP010073_00054 - 0.15 11.9 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Sigma70_r4_2 PF08281.12 CP010073_00054 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 PcfJ PF14284.6 CP011017_00002 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP011017_00002 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 CP011017_00003 - 1.7e-97 327.1 8.2 2.3e-97 326.6 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP011017_00003 - 4.7e-12 46.0 2.7 6.4e-12 45.6 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP011017_00003 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP011017_00003 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP011017_00003 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP011017_00003 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP011017_00003 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP011017_00003 - 0.055 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP011017_00003 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP011017_00003 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP011017_00003 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP011017_00003 - 0.42 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP011017_00003 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP011017_00003 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP011017_00003 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP011017_00003 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP011017_00003 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 CP011017_00004 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP011017_00006 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP011017_00006 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP011017_00006 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CP011017_00007 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP011017_00008 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP011017_00008 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP011017_00008 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP011017_00008 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CP011017_00009 - 7e-106 354.8 0.1 9.7e-106 354.3 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP011017_00009 - 9.6e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP011017_00009 - 7.2e-16 58.1 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 CP011017_00010 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP011017_00010 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP011017_00010 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP011017_00010 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP011017_00010 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP011017_00010 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CP011017_00010 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CP011017_00010 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP011017_00010 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP011017_00010 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP011017_00010 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP011017_00010 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 CP011017_00010 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CP011017_00010 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 CP011017_00010 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 CP011017_00010 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CP011017_00010 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CP011017_00010 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 CP011017_00010 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 CP011017_00010 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP011017_00010 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 CP011017_00010 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 CP011017_00010 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP011017_00010 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP011017_00010 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP011017_00010 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP011017_00010 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP011017_00010 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CP011017_00010 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 CP011017_00010 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP011017_00010 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP011017_00010 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CP011017_00011 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP011017_00011 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CP011017_00012 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 CP011017_00012 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 CP011017_00012 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain VirB8 PF04335.13 CP011017_00013 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP011017_00013 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CP011017_00014 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 CP011017_00014 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 CP011017_00014 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CP011017_00015 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP011017_00015 - 0.065 13.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 CP011017_00015 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) T4SS PF07996.11 CP011017_00016 - 1e-28 101.1 13.2 1.5e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP011017_00016 - 0.0033 17.5 0.6 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 CP011017_00016 - 0.013 16.1 0.8 0.036 14.7 0.2 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Tissue_fac PF01108.17 CP011017_00016 - 0.043 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Tissue factor AATF-Che1 PF13339.6 CP011017_00016 - 0.45 11.2 11.4 0.41 11.3 4.5 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 CP011017_00017 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP011017_00017 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP011017_00017 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP011017_00017 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CP011017_00018 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 CP011017_00019 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 CP011017_00020 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 CP011017_00020 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 CP011017_00020 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 CP011017_00021 - 2.4e-51 174.8 0.3 5.5e-51 173.6 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP011017_00021 - 6.9e-21 74.3 0.9 1.2e-20 73.5 0.9 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 CP011017_00021 - 0.046 13.2 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated TrbC PF04956.13 CP011017_00022 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP011017_00022 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP011017_00024 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.8 1 1 1 2 2 2 2 CRISPR associated protein Cas2 Resolvase PF00239.21 CP011017_00025 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP011017_00025 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP011017_00025 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP011017_00025 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 CP011017_00026 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP011017_00026 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP011017_00026 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP011017_00026 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP011017_00026 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP011017_00026 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP011017_00026 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 CP011017_00027 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP011017_00028 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CP011017_00030 - 0.0016 18.5 0.4 0.0018 18.3 0.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4223 PF13978.6 CP011017_00031 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 CP011017_00031 - 0.1 12.1 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 CP011017_00032 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP011017_00032 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP011017_00032 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP011017_00032 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold ZYG-11_interact PF05884.12 CP011017_00034 - 0.22 10.9 0.4 0.26 10.7 0.4 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 HTH_46 PF15977.5 CP011017_00035 - 0.00021 21.2 5.7 0.12 12.4 0.6 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP011017_00035 - 0.046 13.8 1.9 0.067 13.3 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DndE PF08870.11 CP011017_00035 - 0.29 11.4 5.6 0.5 10.7 0.8 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP011017_00035 - 0.3 11.4 6.2 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 CP011017_00035 - 0.32 11.1 8.7 1 9.4 0.3 3.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Relaxase PF03432.14 CP011017_00036 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain Acetyltransf_7 PF13508.7 CP011017_00037 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP011017_00037 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 CP011017_00037 - 0.0083 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NYN PF01936.18 CP011017_00038 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 CP011017_00038 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 CP011017_00038 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) SNF2_N PF00176.23 CP011017_00039 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP011017_00039 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP011017_00039 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP011017_00039 - 9.2e-06 25.5 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP011017_00039 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP011017_00040 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 CP011017_00040 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 CP011017_00041 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP011017_00041 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP011017_00041 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP011017_00041 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP011017_00041 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP011017_00042 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP011017_00042 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP011017_00043 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP011017_00043 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP011017_00043 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP011017_00043 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP011017_00043 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP011017_00044 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP011017_00044 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP011017_00044 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP011017_00044 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP011017_00044 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP011017_00044 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP011017_00044 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 CP011017_00045 - 0.0057 16.0 1.4 0.0057 16.0 1.4 2.0 3 0 0 3 3 3 1 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 CP011017_00045 - 1.9 7.5 5.4 2.3 7.2 5.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus CtsR_C PF17727.1 CP011017_00046 - 0.041 14.0 0.3 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 CP011017_00047 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP011017_00047 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain DUF5442 PF17514.2 CP011017_00049 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) EFG_C PF00679.24 CP011017_00050 - 1.3e-17 63.6 0.0 1.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CP011017_00050 - 4.1e-08 33.0 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 CP013033_00002 - 2.5e-59 200.1 0.3 3.4e-59 199.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP013033_00002 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP013033_00002 - 9.3e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP013033_00002 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP013033_00002 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP013033_00002 - 0.00029 21.2 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP013033_00002 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP013033_00002 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP013033_00002 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 CP013033_00002 - 0.15 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B LysE PF01810.18 CP013033_00003 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP013033_00003 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP013033_00003 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP013033_00003 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP013033_00003 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP013033_00003 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP013033_00003 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP013033_00003 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP013033_00003 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 CP013033_00004 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP013033_00004 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP013033_00004 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP013033_00004 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP013033_00004 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP013033_00005 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP013033_00005 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP013033_00006 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP013033_00006 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP013033_00006 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP013033_00006 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP013033_00006 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP013033_00007 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP013033_00008 - 2e-16 59.7 0.9 5.7e-16 58.2 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP013033_00008 - 6.5e-08 32.8 8.6 6.5e-08 32.8 8.6 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP013033_00008 - 2.5e-06 27.8 1.7 4.8e-05 23.7 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP013033_00008 - 1.1e-05 25.2 2.0 0.0011 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP013033_00008 - 2.7e-05 24.6 0.7 0.00022 21.7 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase HTH_19 PF12844.7 CP013033_00009 - 5.9e-05 23.0 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 CP013033_00009 - 0.0013 18.8 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CP013033_00009 - 0.0024 17.9 0.0 0.18 11.9 0.1 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CP013033_00009 - 0.0046 16.5 0.0 0.062 12.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Imm3 PF14425.6 CP013033_00009 - 0.028 14.5 0.2 0.057 13.5 0.2 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 YdaS_antitoxin PF15943.5 CP013033_00009 - 0.028 14.3 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_AsnC-type PF13404.6 CP013033_00009 - 0.041 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Crp PF00325.20 CP013033_00009 - 0.053 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_28 PF13518.6 CP013033_00009 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 CP013033_00009 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Mga PF08280.11 CP013033_00009 - 0.097 12.7 2.9 1.8 8.7 0.2 3.0 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 CP013033_00009 - 0.21 11.0 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Relaxase PF03432.14 CP013033_00010 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP013033_00011 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP013033_00011 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP013033_00011 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP013033_00011 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP013033_00011 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Sds3 PF08598.11 CP013033_00012 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP013033_00012 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP013033_00012 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 CP013033_00014 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 CP013033_00015 - 3.6e-08 33.7 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP013033_00015 - 0.083 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain 5_3_exonuc PF01367.20 CP013033_00015 - 0.083 13.5 4.7 0.46 11.1 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Toprim_4 PF13662.6 CP013033_00015 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain DUF4223 PF13978.6 CP013033_00016 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP013033_00016 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 CP013033_00017 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 CP013033_00018 - 2.6e-30 105.7 7.7 4.2e-30 105.0 7.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CP013033_00018 - 1.6e-26 93.2 0.7 2.2e-26 92.7 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CP013033_00018 - 4.7e-06 25.6 0.7 7e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 CP013033_00018 - 0.0036 17.4 0.7 0.012 15.7 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ORC6 PF05460.13 CP013033_00018 - 0.011 15.0 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HicB_lk_antitox PF15919.5 CP013033_00020 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP013033_00020 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 CP013033_00021 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP013033_00021 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP013033_00021 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP013033_00021 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP013033_00021 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP013033_00021 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 CP013033_00022 - 0.088 12.6 4.3 0.038 13.8 2.0 1.5 1 1 1 2 2 2 0 Group B Rotavirus Non-structural protein 5 FeoB_associated PF12669.7 CP013033_00022 - 0.4 11.1 1.6 1.5 9.3 0.3 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Resolvase PF00239.21 CP013033_00024 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP013033_00024 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP013033_00024 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP013033_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP013033_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP013033_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP013033_00027 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP013033_00027 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP013033_00028 - 2.1e-51 174.9 0.9 5.2e-51 173.7 0.9 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP013033_00028 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP013033_00028 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP013033_00028 - 0.038 14.1 5.4 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 CP013033_00029 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP013033_00029 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP013033_00029 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP013033_00029 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP013033_00029 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 CP013033_00030 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 CP013033_00031 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP013033_00032 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP013033_00032 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP013033_00032 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP013033_00032 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP013033_00033 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP013033_00033 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP013033_00033 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP013033_00033 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP013033_00033 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 CP013033_00033 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 CP013033_00033 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 CP013033_00033 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 CP013033_00034 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP013033_00034 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP013033_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP013033_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP013033_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP013033_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP013033_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP013033_00037 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP013033_00037 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP013033_00038 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP013033_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP013033_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP013033_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP013033_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP013033_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP013033_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP013033_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP013033_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP013033_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP013033_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP013033_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP013033_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP013033_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP013033_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP013033_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP013033_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP013033_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP013033_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP013033_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP013033_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP013033_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP013033_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP013033_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP013033_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP013033_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP013033_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP013033_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP013033_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP013033_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP013033_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP013033_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP013033_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP013033_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP013033_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP013033_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP013033_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP013033_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP013033_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP013033_00041 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP013033_00041 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP013033_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP013033_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP013033_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP013033_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP013033_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP013033_00046 - 1.7e-97 327.1 8.2 2.3e-97 326.6 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP013033_00046 - 4.3e-12 46.1 2.6 6.4e-12 45.6 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP013033_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP013033_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP013033_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP013033_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP013033_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP013033_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP013033_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP013033_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP013033_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP013033_00046 - 0.43 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP013033_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP013033_00046 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP013033_00046 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP013033_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP013033_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TrbC PF04956.13 CP013035_00002 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP013035_00002 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP013035_00004 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP013035_00004 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 CP013035_00005 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP013035_00005 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP013035_00005 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP013035_00005 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 CP013035_00006 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP013035_00006 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP013035_00006 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 CP013035_00006 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CP013035_00006 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP013035_00006 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 CP013035_00006 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 CP013035_00007 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CP013035_00009 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 CP013035_00009 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 CP013035_00009 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 CP013035_00010 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 CP013035_00010 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 CP013035_00010 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 CP013035_00010 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 CP013035_00011 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP013035_00011 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 CP013035_00012 - 2.3e-08 34.3 0.0 4.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP013035_00012 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP013035_00012 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP013035_00012 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 CP013035_00013 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 CP013035_00015 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP013035_00015 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP013035_00015 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CP013035_00016 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP013035_00016 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP013035_00016 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP013035_00016 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP013035_00016 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 CP013035_00017 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain Acetyltransf_7 PF13508.7 CP013035_00018 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP013035_00018 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family SNF2_N PF00176.23 CP013035_00019 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP013035_00019 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP013035_00019 - 9.8e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP013035_00019 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP013035_00019 - 2.9e-05 24.5 0.6 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP013035_00020 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 CP013035_00021 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP013035_00021 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP013035_00021 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP013035_00021 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP013035_00021 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP013035_00022 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP013035_00022 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP013035_00023 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP013035_00023 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP013035_00023 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP013035_00023 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP013035_00023 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP013035_00024 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP013035_00024 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP013035_00024 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP013035_00024 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP013035_00024 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP013035_00024 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP013035_00024 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 CP013035_00025 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 CP013035_00026 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP013035_00026 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 CP013035_00027 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon APH PF01636.23 CP013035_00028 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CP013035_00028 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CP013035_00028 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family GTP_EFTU PF00009.27 CP013035_00029 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP013035_00029 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP013035_00029 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP013035_00029 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP013035_00029 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP013035_00029 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP013035_00029 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP013035_00029 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP013035_00029 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 CP013035_00031 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP013035_00031 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 CP013035_00032 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP013035_00032 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 CP013035_00032 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 CP013035_00032 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 CP013035_00032 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP013035_00032 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain Redoxin PF08534.10 CP013035_00033 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP013035_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP013035_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP013035_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CP013035_00036 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP013035_00037 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP013035_00037 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP013035_00037 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP013035_00037 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CP013035_00038 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP013035_00038 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP013035_00038 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP013035_00038 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 CP013035_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP013035_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP013035_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP013035_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP013035_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP013035_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP013035_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP013035_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP013035_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP013035_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP013035_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP013035_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP013035_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP013035_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP013035_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP013035_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP013035_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP013035_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP013035_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP013035_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP013035_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP013035_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP013035_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP013035_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP013035_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP013035_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP013035_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP013035_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP013035_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP013035_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP013035_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CP013035_00040 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP013035_00040 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CP013035_00041 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP013035_00041 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 CP013035_00042 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP013035_00042 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CP013035_00043 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP013035_00043 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CP013035_00044 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP013035_00044 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP013035_00044 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 CP013035_00045 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP013035_00045 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP013035_00045 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP013035_00045 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP013035_00045 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 CP013035_00045 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 CP013035_00045 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 CP013035_00045 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 CP013035_00046 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP013035_00046 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP013035_00046 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP013035_00046 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CP013035_00047 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 CP013035_00048 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP013035_00048 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP013035_00048 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP013035_00048 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP013035_00048 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP013035_00048 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 CP013035_00049 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP013035_00049 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP013035_00049 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP013035_00049 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP013035_00049 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 CP013035_00050 - 2e-06 28.0 0.4 5.3e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 CagE, TrbE, VirB family, component of type IV transporter system AAA_10 PF12846.7 CP013035_00050 - 7.4e-06 25.1 1.2 2e-05 23.7 1.2 1.6 1 1 0 1 1 1 1 AAA-like domain HNOBA PF07701.14 CP013035_00050 - 0.017 14.6 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 CP013035_00050 - 0.2 11.6 0.0 0.47 10.4 0.0 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like CagX PF03524.15 CP013037_00002 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP013037_00002 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 CP013037_00003 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP013037_00003 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CP013037_00004 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP013037_00004 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CP013037_00005 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP013037_00005 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP013037_00005 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 CP013037_00006 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP013037_00006 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP013037_00006 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP013037_00006 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP013037_00006 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 CP013037_00006 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 CP013037_00006 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 CP013037_00006 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 CP013037_00007 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP013037_00007 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP013037_00007 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP013037_00007 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CP013037_00008 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 CP013037_00009 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 CP013037_00010 - 6.4e-29 100.4 0.0 1.1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP013037_00010 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP013037_00010 - 0.011 15.3 0.4 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP013037_00010 - 0.061 13.3 0.1 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP013037_00010 - 1.1 9.4 7.5 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 CP013037_00011 - 2.1e-51 174.9 0.9 5.2e-51 173.7 0.9 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP013037_00011 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP013037_00011 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP013037_00011 - 0.038 14.1 5.4 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 CP013037_00012 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP013037_00012 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP013037_00014 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP013037_00014 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 CP013037_00015 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP013037_00015 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP013037_00015 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP013037_00015 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat GBR_NSP5 PF17580.2 CP013037_00017 - 0.088 12.6 4.3 0.038 13.8 2.0 1.5 1 1 1 2 2 2 0 Group B Rotavirus Non-structural protein 5 FeoB_associated PF12669.7 CP013037_00017 - 0.4 11.1 1.6 1.5 9.3 0.3 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein AAA_25 PF13481.6 CP013037_00018 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP013037_00018 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP013037_00018 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP013037_00018 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP013037_00018 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP013037_00018 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicB_lk_antitox PF15919.5 CP013037_00019 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP013037_00019 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain Pkinase PF00069.25 CP013037_00021 - 2.6e-30 105.7 7.7 4.2e-30 105.0 7.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CP013037_00021 - 1.6e-26 93.2 0.7 2.2e-26 92.7 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CP013037_00021 - 4.7e-06 25.6 0.7 7e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 CP013037_00021 - 0.0036 17.4 0.7 0.012 15.7 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ORC6 PF05460.13 CP013037_00021 - 0.011 15.0 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TOPRIM_C PF16898.5 CP013037_00022 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM DUF4223 PF13978.6 CP013037_00023 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP013037_00023 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 CP013037_00024 - 3.6e-08 33.7 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP013037_00024 - 0.083 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain 5_3_exonuc PF01367.20 CP013037_00024 - 0.083 13.5 4.7 0.46 11.1 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Toprim_4 PF13662.6 CP013037_00024 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain DUF2400 PF09674.10 CP013037_00025 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 CP013037_00027 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP013037_00027 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP013037_00027 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CP013037_00028 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP013037_00028 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP013037_00028 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP013037_00028 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP013037_00028 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 CP013037_00029 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 CP013037_00030 - 5.9e-05 23.0 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 CP013037_00030 - 0.0013 18.8 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CP013037_00030 - 0.0024 17.9 0.0 0.18 11.9 0.1 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CP013037_00030 - 0.0046 16.5 0.0 0.062 12.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Imm3 PF14425.6 CP013037_00030 - 0.028 14.5 0.2 0.057 13.5 0.2 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 YdaS_antitoxin PF15943.5 CP013037_00030 - 0.028 14.3 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_AsnC-type PF13404.6 CP013037_00030 - 0.041 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Crp PF00325.20 CP013037_00030 - 0.053 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_28 PF13518.6 CP013037_00030 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 CP013037_00030 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Mga PF08280.11 CP013037_00030 - 0.097 12.7 2.9 1.8 8.7 0.2 3.0 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 CP013037_00030 - 0.21 11.0 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 SNF2_N PF00176.23 CP013037_00031 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP013037_00031 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP013037_00031 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP013037_00031 - 1.3e-05 25.1 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP013037_00031 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP013037_00032 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 CP013037_00033 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP013037_00033 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP013037_00033 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP013037_00033 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP013037_00033 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP013037_00034 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP013037_00034 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP013037_00035 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP013037_00035 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP013037_00035 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP013037_00035 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP013037_00035 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP013037_00036 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP013037_00036 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP013037_00036 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP013037_00036 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP013037_00036 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP013037_00036 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP013037_00036 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP013037_00036 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP013037_00036 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase GTP_EFTU PF00009.27 CP013037_00037 - 8.1e-59 198.4 0.4 1.1e-58 198.0 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP013037_00037 - 1.3e-22 79.9 0.0 3.5e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP013037_00037 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP013037_00037 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP013037_00037 - 1.8e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP013037_00037 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP013037_00037 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP013037_00037 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP013037_00037 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 CP013037_00039 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP013037_00039 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 CP013037_00040 - 1.2e-97 327.5 8.2 1.6e-97 327.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP013037_00040 - 3.6e-12 46.4 2.9 5.3e-12 45.9 0.1 2.8 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP013037_00040 - 0.011 15.5 1.7 0.028 14.2 1.7 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 CP013037_00040 - 0.077 12.9 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zinc_ribbon_9 PF14369.6 CP013037_00040 - 0.22 11.8 0.7 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon HTH_34 PF13601.6 CP013037_00040 - 0.22 11.7 2.8 0.74 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain Redoxin PF08534.10 CP013037_00041 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP013037_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP013037_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP013037_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CP013037_00044 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP013037_00045 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP013037_00045 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP013037_00045 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP013037_00045 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CP013037_00046 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP013037_00046 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP013037_00046 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP013037_00046 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 CP013037_00047 - 4.6e-54 183.3 0.0 5.3e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP013037_00047 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP013037_00047 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP013037_00047 - 0.00022 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP013037_00047 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP013037_00047 - 0.0027 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP013037_00047 - 0.0031 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP013037_00047 - 0.0037 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP013037_00047 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP013037_00047 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP013037_00047 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP013037_00047 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP013037_00047 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP013037_00047 - 0.021 14.8 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP013037_00047 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP013037_00047 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP013037_00047 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP013037_00047 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP013037_00047 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 CP013037_00047 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CP013037_00047 - 0.038 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.12 CP013037_00047 - 0.04 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP013037_00047 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP013037_00047 - 0.062 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP013037_00047 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP013037_00047 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP013037_00047 - 0.092 12.7 0.4 0.24 11.3 0.2 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP013037_00047 - 0.12 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP013037_00047 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CP013037_00047 - 0.15 12.6 0.1 0.38 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CP013037_00047 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP013037_00047 - 0.22 12.0 2.5 0.32 11.5 1.3 1.7 1 1 0 1 1 1 0 AAA domain TrbI PF03743.14 CP013037_00048 - 1.1e-10 41.6 0.1 1.3e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP013037_00048 - 0.0018 17.4 0.1 0.002 17.3 0.1 1.1 1 0 0 1 1 1 1 HaeIII restriction endonuclease Adenyl_transf PF04439.12 CP013117_00001 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 CP013117_00002 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CP013117_00002 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CP013117_00002 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CP013117_00002 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CP013117_00002 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CP013117_00002 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CP013117_00002 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CP013117_00002 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 CP013117_00003 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CP013117_00003 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CP013117_00003 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 CP013117_00004 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 CP013117_00005 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP013117_00005 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 CP013117_00006 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP013117_00006 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP013117_00006 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP013117_00006 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP013117_00006 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP013117_00006 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP013117_00006 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP013117_00006 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP013117_00006 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 CP013117_00007 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP013117_00007 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP013117_00007 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP013117_00007 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP013117_00007 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP013117_00008 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP013117_00008 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP013117_00009 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP013117_00009 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP013117_00009 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP013117_00009 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP013117_00009 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP013117_00010 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP013117_00011 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP013117_00011 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP013117_00011 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP013117_00011 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP013117_00011 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 CP013117_00012 - 0.0008 19.8 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP013117_00012 - 0.032 14.5 0.1 0.066 13.4 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Peptidase_S24 PF00717.23 CP013117_00013 - 3.3e-12 46.2 0.0 6.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Phage_CI_repr PF07022.13 CP013117_00013 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4_2 PF08281.12 CP013117_00013 - 0.048 13.3 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_10 PF04967.12 CP013117_00013 - 0.056 13.3 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain Fe_dep_repress PF01325.19 CP013117_00013 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 CP013117_00013 - 0.18 11.6 0.0 0.73 9.7 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain RepB-RCR_reg PF10723.9 CP013117_00014 - 0.057 13.4 1.2 0.13 12.3 1.2 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB PdaC PF13739.6 CP013117_00014 - 2.4 9.2 5.8 9.8 7.2 5.8 2.0 1 1 0 1 1 1 0 Deacetylase PdaC CdhC PF03598.15 CP013117_00015 - 0.052 13.4 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit SinI PF08671.10 CP013117_00015 - 0.076 12.8 0.1 0.076 12.8 0.1 2.2 3 0 0 3 3 3 0 Anti-repressor SinI Ank_2 PF12796.7 CP013117_00016 - 2.1e-05 25.0 0.1 3.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CP013117_00016 - 0.011 16.2 0.1 0.18 12.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat DUF3447 PF11929.8 CP013117_00016 - 0.012 15.6 3.0 0.013 15.5 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) MethyltransfD12 PF02086.15 CP013117_00017 - 1.5e-28 100.2 6.6 3e-28 99.2 6.6 1.4 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Phage_GPD PF05954.11 CP013117_00018 - 3.2e-06 26.7 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) PTH2 PF01981.16 CP013117_00018 - 0.031 14.6 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Phage_tail_X PF05489.12 CP013117_00019 - 2.5e-10 39.9 0.0 3.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Phage Tail Protein X Phage_P2_GpU PF06995.11 CP013117_00020 - 1.2e-18 66.9 0.0 1.5e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Phage P2 GpU PhageMin_Tail PF10145.9 CP013117_00021 - 1.5e-22 80.4 18.9 1.5e-22 80.4 18.9 3.8 2 1 2 4 4 4 2 Phage-related minor tail protein DUF3450 PF11932.8 CP013117_00021 - 4.6e-06 26.1 0.6 0.15 11.3 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3450) DLP_helical PF18709.1 CP013117_00021 - 0.017 14.3 0.4 0.017 14.3 0.4 3.2 2 1 1 3 3 3 0 Dynamin-like helical domain Dor1 PF04124.12 CP013117_00021 - 0.037 12.7 1.4 0.063 12.0 0.6 1.8 2 0 0 2 2 2 0 Dor1-like family HD_2 PF12917.7 CP013117_00021 - 0.06 13.1 2.9 0.076 12.8 0.1 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme HAUS-augmin3 PF14932.6 CP013117_00021 - 0.064 12.8 8.5 0.53 9.8 2.4 3.4 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF16 PF01519.16 CP013117_00021 - 0.086 13.3 3.1 1.1 9.8 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF3847 PF12958.7 CP013117_00021 - 0.11 12.6 4.4 1.4 9.1 0.0 3.8 4 1 1 5 5 4 0 Protein of unknown function (DUF3847) APC1_C PF18122.1 CP013117_00021 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain BLOC1_2 PF10046.9 CP013117_00021 - 0.15 12.4 15.0 0.15 12.4 0.3 5.8 7 0 0 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CP013117_00021 - 0.61 10.1 19.4 0.75 9.8 1.3 4.7 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CP013117_00021 - 0.87 9.8 4.6 11 6.2 1.0 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 CP013117_00021 - 1.2 7.9 6.5 6.7 5.5 1.3 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4795 PF16043.5 CP013117_00021 - 1.3 8.5 10.7 0.49 10.0 1.7 3.5 2 2 0 3 3 3 0 Domain of unknown function (DUF4795) Sigma70_ner PF04546.13 CP013117_00021 - 2.2 8.1 7.5 29 4.5 1.8 3.5 4 0 0 4 4 4 0 Sigma-70, non-essential region APG6_N PF17675.1 CP013117_00021 - 4.9 7.7 5.9 38 4.8 0.5 3.1 3 1 0 3 3 3 0 Apg6 coiled-coil region MgtE PF01769.16 CP013117_00022 - 0.065 13.6 4.9 0.072 13.5 4.9 1.0 1 0 0 1 1 1 0 Divalent cation transporter DUF4234 PF14018.6 CP013117_00022 - 0.5 10.5 6.7 1.1 9.4 6.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) DUF2207 PF09972.9 CP013117_00022 - 5.5 5.6 8.9 6 5.5 8.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_TAC_7 PF10109.9 CP013117_00023 - 5.2e-05 23.3 0.0 6.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 Phage_tube PF04985.14 CP013117_00024 - 1e-29 103.4 0.0 1.1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein FII Phage_sheath_1C PF17482.2 CP013117_00025 - 0.0025 17.7 0.3 0.031 14.3 0.2 2.6 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain DUF1353 PF07087.11 CP013117_00027 - 5.8e-19 67.6 0.0 6.9e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) DUF4376 PF14301.6 CP013117_00028 - 1.3e-10 41.6 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4376) CENP-X PF09415.10 CP013117_00028 - 0.022 15.0 0.1 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF3751 PF12571.8 CP013117_00029 - 8e-38 129.9 0.0 1.7e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 Phage tail-collar fibre protein BppL_N PF18338.1 CP013117_00029 - 0.0018 18.0 0.4 0.0042 16.8 0.4 1.6 1 0 0 1 1 1 1 Lower baseplate protein N-terminal domain Peptidase_M28 PF04389.17 CP013117_00029 - 0.062 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Tail_P2_I PF09684.10 CP013117_00030 - 2.5e-23 82.5 0.0 3.6e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) Acp26Ab PF05777.12 CP013117_00030 - 0.08 13.6 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) SIN1_PH PF16979.5 CP013117_00030 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Baseplate_J PF04865.14 CP013117_00031 - 5.1e-24 84.8 0.0 9.1e-24 84.0 0.0 1.4 1 1 0 1 1 1 1 Baseplate J-like protein GPW_gp25 PF04965.14 CP013117_00032 - 1.3e-13 50.6 0.0 1.5e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Gene 25-like lysozyme Phage_base_V PF04717.12 CP013117_00033 - 1.1e-18 67.2 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector WTF PF03303.13 CP013117_00033 - 0.14 11.9 0.5 0.19 11.4 0.5 1.1 1 0 0 1 1 1 0 WTF protein DUF1804 PF08822.11 CP013117_00034 - 1e-09 38.6 0.2 1.2e-09 38.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_29 PF13551.6 CP013117_00034 - 0.0057 16.6 0.0 0.079 13.0 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 CP013117_00034 - 0.0077 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Mu-like_Pro PF10123.9 CP013117_00035 - 1.7e-25 90.2 1.1 2.3e-25 89.8 1.1 1.2 1 0 0 1 1 1 1 Mu-like prophage I protein DUF812 PF05667.11 CP013117_00035 - 0.00088 18.3 14.1 0.0012 17.8 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 CP013117_00035 - 0.0032 16.4 15.8 0.0052 15.7 15.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein HALZ PF02183.18 CP013117_00035 - 0.0036 17.5 3.9 0.0036 17.5 3.9 2.7 2 1 0 2 2 2 1 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 CP013117_00035 - 0.0063 16.7 26.1 0.0063 16.7 26.1 1.8 1 1 0 1 1 1 1 Tropomyosin like Alpha-2-MRAP_C PF06401.11 CP013117_00035 - 0.026 14.5 13.1 0.014 15.4 10.4 1.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain HemX PF04375.14 CP013117_00035 - 0.055 12.7 10.2 0.17 11.2 10.7 1.5 2 0 0 2 2 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FlaC_arch PF05377.11 CP013117_00035 - 0.064 13.6 0.6 0.064 13.6 0.6 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 CP013117_00035 - 0.098 12.7 16.6 0.18 11.9 16.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 CP013117_00035 - 0.1 11.7 9.9 0.15 11.2 9.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 CP013117_00035 - 0.11 12.1 8.3 0.19 11.3 8.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Golgin_A5 PF09787.9 CP013117_00035 - 0.13 11.7 12.9 0.2 11.1 12.9 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 FlgN PF05130.12 CP013117_00035 - 0.15 12.6 15.7 0.31 11.6 15.7 1.6 1 0 0 1 1 1 0 FlgN protein TPR_MLP1_2 PF07926.12 CP013117_00035 - 0.15 12.2 25.0 1.9 8.5 25.0 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 CP013117_00035 - 0.21 11.8 7.5 0.47 10.6 7.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PCRF PF03462.18 CP013117_00035 - 0.33 10.8 11.2 0.75 9.6 11.2 1.6 1 0 0 1 1 1 0 PCRF domain DUF5320 PF17253.2 CP013117_00035 - 0.35 12.0 6.6 7.3 7.7 0.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF3578 PF12102.8 CP013117_00035 - 0.77 9.3 6.4 0.12 12.0 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3578) Uso1_p115_C PF04871.13 CP013117_00035 - 0.81 10.1 23.3 0.49 10.8 20.6 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fzo_mitofusin PF04799.13 CP013117_00035 - 1.2 8.6 4.4 1.4 8.4 3.4 1.6 1 1 0 1 1 1 0 fzo-like conserved region DUF2203 PF09969.9 CP013117_00035 - 1.6 9.4 5.7 4.9 7.9 5.7 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Snapin_Pallidin PF14712.6 CP013117_00035 - 1.8 9.0 12.1 0.1 13.0 3.2 2.7 2 0 0 2 2 2 0 Snapin/Pallidin T3SS_basalb_I PF17001.5 CP013117_00035 - 2.9 8.6 9.2 1.1 9.9 2.9 2.6 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI ZapB PF06005.12 CP013117_00035 - 3.2 8.3 27.1 0.9 10.0 11.6 3.0 2 0 0 2 2 2 0 Cell division protein ZapB Cwf_Cwc_15 PF04889.12 CP013117_00035 - 3.4 7.3 16.3 4.7 6.9 16.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMPIT PF07851.13 CP013117_00035 - 4.4 6.5 8.7 6.8 5.8 8.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein MutS_IV PF05190.18 CP013117_00035 - 4.6 7.7 13.0 4.7 7.6 2.2 3.6 3 0 0 3 3 3 0 MutS family domain IV LMBR1 PF04791.16 CP013117_00035 - 5.4 5.8 6.0 6.4 5.6 6.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 CP013117_00035 - 6 6.7 14.6 0.4 10.5 3.6 2.8 2 0 0 2 2 2 0 Septum formation initiator 5_nucleotid PF05761.14 CP013117_00035 - 6.5 5.5 8.6 9.6 5.0 8.6 1.2 1 0 0 1 1 1 0 5' nucleotidase family Csm1_N PF18504.1 CP013117_00035 - 6.6 7.2 20.7 0.42 11.0 4.3 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF2508 PF10704.9 CP013117_00035 - 7.5 6.8 12.7 12 6.1 3.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) HalX PF08663.10 CP013117_00035 - 9.3 6.7 17.5 2.7 8.4 2.4 2.5 1 1 1 2 2 2 0 HalX domain Mu-like_gpT PF10124.9 CP013117_00036 - 3.4e-75 253.1 2.8 1e-37 130.0 0.2 3.0 1 1 2 3 3 3 3 Mu-like prophage major head subunit gpT SplA PF11132.8 CP013117_00037 - 0.0073 16.1 0.7 0.37 10.6 0.2 2.2 1 1 1 2 2 2 2 Transcriptional regulator protein (SplA) tRNA-synt_1g PF09334.11 CP013117_00037 - 0.065 12.0 4.2 0.073 11.8 4.2 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (M) DNAP_B_exo_N PF08452.10 CP013117_00037 - 1.6 8.2 6.8 19 4.8 0.0 3.3 3 0 0 3 3 3 0 DNA polymerase family B exonuclease domain, N-terminal Peptidase_M15_3 PF08291.11 CP013117_00040 - 1.4e-23 83.1 0.0 1.6e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase M15 Peptidase_M15_2 PF05951.13 CP013117_00040 - 4e-06 26.6 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Extensin-like_C PF06904.12 CP013117_00040 - 0.07 13.2 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Extensin-like protein C-terminus Phage_holin_3_3 PF16083.5 CP013117_00044 - 3.3e-10 39.9 3.8 4e-10 39.7 3.8 1.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III Phage_holin_3_1 PF05106.12 CP013117_00044 - 0.0016 18.8 1.7 0.0047 17.3 1.6 1.8 1 1 0 1 1 1 1 Phage holin family (Lysis protein S) DUF3397 PF11877.8 CP013117_00044 - 0.053 13.7 3.4 0.076 13.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DUF3959 PF13105.6 CP013117_00044 - 0.11 12.0 1.9 0.12 11.8 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) ResIII PF04851.15 CP013117_00045 - 0.002 18.2 2.7 0.0029 17.6 0.5 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Terminase_6C PF17289.2 CP013117_00045 - 0.064 13.4 0.0 1 9.5 0.0 2.3 1 1 0 1 1 1 0 Terminase RNaseH-like domain DUF935 PF06074.12 CP013117_00046 - 2.8e-44 151.8 0.0 1.8e-43 149.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF935) DUF2119 PF09892.9 CP013117_00046 - 0.072 12.5 0.6 0.17 11.3 0.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Phage_Mu_F PF04233.14 CP013117_00047 - 1.6e-21 77.1 0.9 3.8e-21 75.9 0.9 1.7 1 0 0 1 1 1 1 Phage Mu protein F like protein PBECR2 PF18810.1 CP013117_00047 - 5.8e-14 52.4 0.5 1.4e-13 51.2 0.5 1.6 1 0 0 1 1 1 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_tail_S PF05069.13 CP013117_00048 - 1.6e-14 54.0 0.1 1.9e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Phage virion morphogenesis family BORCS7 PF16088.5 CP013117_00048 - 0.014 15.6 1.3 0.03 14.6 1.0 1.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DUF2387 PF09526.10 CP013117_00049 - 0.00073 19.6 0.3 0.00076 19.6 0.3 1.2 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.7 CP013117_00049 - 0.0045 16.9 1.5 0.0063 16.5 1.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 CP013117_00049 - 0.07 13.5 0.1 0.085 13.3 0.1 1.1 1 0 0 1 1 1 0 Restriction alleviation protein Lar eIF-5_eIF-2B PF01873.17 CP013117_00049 - 0.11 12.4 2.0 0.15 11.9 2.0 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 TFIIS_C PF01096.18 CP013117_00049 - 0.13 12.2 5.2 0.85 9.5 5.2 2.0 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) DUF1660 PF07874.11 CP013117_00049 - 0.15 12.5 2.1 0.74 10.3 0.3 2.0 1 1 1 2 2 2 0 Prophage protein (DUF1660) zinc_ribbon_2 PF13240.6 CP013117_00049 - 0.24 11.2 2.6 3.3 7.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CP013117_00049 - 0.55 10.2 0.2 0.55 10.2 0.2 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon UPF0547 PF10571.9 CP013117_00049 - 1.1 9.4 4.2 7.6 6.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 YopX PF09643.10 CP013117_00052 - 1.3e-18 67.3 5.8 2.7e-18 66.3 5.8 1.5 1 1 0 1 1 1 1 YopX protein MgtE_N PF03448.17 CP013117_00053 - 5.1e-05 23.8 1.7 0.00075 20.1 1.6 2.0 1 1 0 1 1 1 1 MgtE intracellular N domain CRISPR_Cas9_WED PF18061.1 CP013117_00053 - 0.064 13.3 0.2 0.087 12.9 0.2 1.3 1 1 0 1 1 1 0 CRISPR-Cas9 WED domain RNA_capsid PF03035.14 CP013117_00054 - 0.034 14.2 0.3 0.034 14.2 0.3 1.0 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Phage_Mu_Gam PF07352.12 CP013117_00055 - 1.2e-33 116.2 4.5 1.4e-33 116.0 4.5 1.0 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein NPM1-C PF16276.5 CP013117_00055 - 0.054 13.5 0.1 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain YvrJ PF12841.7 CP013117_00055 - 0.38 10.3 2.6 17 5.1 0.1 3.1 3 0 0 3 3 3 0 YvrJ protein family DUF4406 PF14359.6 CP013117_00056 - 0.0002 21.8 0.0 0.00033 21.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4406) DUF1937 PF09152.10 CP013117_00056 - 0.0077 17.0 0.0 0.016 16.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1937) PVL_ORF50 PF07768.11 CP013117_00057 - 7.3e-05 23.1 0.5 0.0001 22.6 0.4 1.4 1 1 0 1 1 1 1 PVL ORF-50-like family Sigma70_r4 PF04545.16 CP013117_00059 - 2.4e-08 33.4 0.1 3e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 CP013117_00059 - 0.00011 21.8 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 CP013117_00059 - 0.0061 16.6 0.0 0.0095 16.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-70 region 3 HTH_Tnp_ISL3 PF13542.6 CP013117_00059 - 0.0062 15.9 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 CP013117_00059 - 0.014 14.9 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 CP013117_00059 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GerE PF00196.19 CP013117_00059 - 0.022 14.3 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family AAA_22 PF13401.6 CP013117_00060 - 1.2e-19 71.0 0.1 2.9e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CP013117_00060 - 3e-09 36.6 0.8 1.6e-08 34.2 0.8 2.1 1 1 0 1 1 1 1 Bacterial TniB protein AAA_30 PF13604.6 CP013117_00060 - 5.1e-09 36.1 0.0 9.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CP013117_00060 - 1e-06 29.2 0.5 2.4e-05 24.8 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 CP013117_00060 - 2.2e-05 24.0 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 CP013117_00060 - 2.7e-05 24.7 0.4 0.019 15.5 0.1 2.5 1 1 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 CP013117_00060 - 6.3e-05 23.3 0.4 0.00084 19.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CP013117_00060 - 0.00024 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CP013117_00060 - 0.0006 19.8 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CP013117_00060 - 0.00092 19.6 0.3 0.0023 18.4 0.1 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CP013117_00060 - 0.0011 18.8 0.1 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CP013117_00060 - 0.0014 18.6 3.0 0.016 15.1 0.1 2.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 CP013117_00060 - 0.0015 17.9 0.1 0.0034 16.7 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Cys_Met_Meta_PP PF01053.20 CP013117_00060 - 0.0016 17.0 0.0 0.0028 16.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sigma54_activat PF00158.26 CP013117_00060 - 0.002 17.8 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.6 CP013117_00060 - 0.0026 17.6 0.5 0.008 16.0 0.1 2.0 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CP013117_00060 - 0.0027 17.5 0.2 0.0092 15.7 0.1 1.9 2 1 0 2 2 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 CP013117_00060 - 0.0037 17.3 0.1 0.008 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CP013117_00060 - 0.006 16.5 0.1 0.051 13.5 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase ATPase PF06745.13 CP013117_00060 - 0.0096 15.3 0.1 0.019 14.3 0.1 1.6 1 1 0 1 1 1 1 KaiC T2SSE PF00437.20 CP013117_00060 - 0.0099 15.0 0.1 0.017 14.2 0.1 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein TK PF00265.18 CP013117_00060 - 0.016 15.1 0.1 0.04 13.8 0.0 1.8 2 0 0 2 2 1 0 Thymidine kinase Helicase_RecD PF05127.14 CP013117_00060 - 0.019 14.8 0.7 0.12 12.2 0.2 2.1 1 1 1 2 2 2 0 Helicase PhoH PF02562.16 CP013117_00060 - 0.021 14.2 0.2 0.057 12.9 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 CP013117_00060 - 0.028 14.3 0.1 1.8 8.5 0.0 2.4 1 1 0 2 2 2 0 Rad17 P-loop domain HTH_19 PF12844.7 CP013117_00060 - 0.04 14.0 1.0 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain PEPCK_ATP PF01293.20 CP013117_00060 - 0.045 12.4 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_23 PF13476.6 CP013117_00060 - 0.051 14.1 1.5 0.051 14.1 1.5 2.4 2 2 1 3 3 3 0 AAA domain AAA_29 PF13555.6 CP013117_00060 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIE_beta PF02186.15 CP013117_00060 - 0.085 13.1 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 TFIIE beta subunit core domain NB-ARC PF00931.22 CP013117_00060 - 0.097 11.8 0.4 0.43 9.7 0.4 2.1 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 CP013117_00060 - 0.11 13.0 0.2 0.4 11.1 0.0 2.2 2 1 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 CP013117_00060 - 0.18 11.4 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain rve PF00665.26 CP013117_00061 - 2.4e-11 43.8 0.0 5.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 CP013117_00061 - 9.5e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Mu transposase, C-terminal CSRNP_N PF16019.5 CP013117_00061 - 0.33 10.8 4.2 2.1 8.2 0.9 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus HTH_3 PF01381.22 CP013117_00064 - 3.6e-12 46.1 0.2 9.2e-12 44.8 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix Peptidase_S24 PF00717.23 CP013117_00064 - 2.8e-11 43.2 0.0 9.2e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase S24-like HTH_19 PF12844.7 CP013117_00064 - 6.9e-10 38.8 0.2 1.5e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CP013117_00064 - 1.4e-06 28.6 0.0 3.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 CP013117_00064 - 3.6e-05 23.5 0.2 0.00011 22.0 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 CP013117_00064 - 0.009 15.8 0.1 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_8 PF02954.19 CP013117_00064 - 0.047 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 CP013117_00064 - 0.055 13.1 0.3 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 YdaS_antitoxin PF15943.5 CP013117_00064 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR PF00376.23 CP013117_00064 - 0.14 12.0 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 MerR family regulatory protein HTH_24 PF13412.6 CP013117_00064 - 0.15 11.7 0.9 0.66 9.6 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Relaxase PF03432.14 CP013117_00065 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP013117_00066 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP013117_00066 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP013117_00066 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP013117_00066 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP013117_00066 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 CP013117_00067 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP013117_00067 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP013117_00067 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 CP013117_00070 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP013117_00070 - 0.016 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP013117_00070 - 0.017 15.2 6.4 1.2 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 DUF4223 PF13978.6 CP013117_00071 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP013117_00071 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 CP013117_00072 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 CP013117_00073 - 5.1e-29 101.4 6.3 9.5e-29 100.6 6.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CP013117_00073 - 2e-26 92.8 0.9 3.2e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CP013117_00073 - 4e-06 25.9 0.8 5.9e-06 25.3 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 CP013117_00073 - 0.0032 17.5 0.9 0.0087 16.1 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) RIO1 PF01163.22 CP013117_00073 - 0.0073 15.9 2.5 0.0073 15.9 2.5 1.6 2 0 0 2 2 2 1 RIO1 family ORC6 PF05460.13 CP013117_00073 - 0.0086 15.4 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pectate_lyase_3 PF12708.7 CP013117_00073 - 0.068 13.0 0.4 0.14 12.0 0.4 1.4 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pex19 PF04614.12 CP013117_00073 - 3.6 7.3 5.4 7.5 6.2 5.4 1.5 1 0 0 1 1 1 0 Pex19 protein family HicB_lk_antitox PF15919.5 CP013117_00075 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP013117_00075 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 CP013117_00076 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP013117_00076 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP013117_00076 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP013117_00076 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP013117_00076 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP013117_00076 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 CP013117_00077 - 0.013 15.3 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 CP013117_00079 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP013117_00079 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP013117_00079 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP013117_00079 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP013117_00080 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP013117_00080 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP013117_00082 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP013117_00082 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP013117_00083 - 1.3e-51 175.6 0.7 3e-51 174.5 0.7 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP013117_00083 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 CP013117_00083 - 0.046 13.2 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 CP013117_00084 - 1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP013117_00084 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 CP013117_00085 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP013117_00085 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP013117_00085 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP013117_00085 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP013117_00085 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP013117_00085 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 CP013117_00086 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP013117_00087 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP013117_00087 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP013117_00087 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP013117_00087 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP013117_00088 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP013117_00088 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP013117_00088 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 CP013117_00088 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 CP013117_00088 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 CP013117_00088 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 CP013117_00089 - 4.7e-29 101.7 31.2 4.7e-29 101.7 31.2 1.8 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP013117_00089 - 0.22 11.3 1.3 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP013117_00089 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP013117_00090 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP013117_00090 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP013117_00091 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP013117_00091 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP013117_00092 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP013117_00092 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP013117_00093 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP013117_00093 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP013117_00094 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP013117_00094 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP013117_00094 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP013117_00094 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP013117_00094 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP013117_00094 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP013117_00094 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP013117_00094 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP013117_00094 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP013117_00094 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP013117_00094 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP013117_00094 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP013117_00094 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP013117_00094 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP013117_00094 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP013117_00094 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP013117_00094 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP013117_00094 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP013117_00094 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP013117_00094 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP013117_00094 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP013117_00094 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP013117_00094 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP013117_00094 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP013117_00094 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP013117_00094 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP013117_00094 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP013117_00094 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP013117_00094 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP013117_00094 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP013117_00094 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP013117_00095 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP013117_00095 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP013117_00095 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP013117_00095 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP013117_00096 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP013117_00096 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP013117_00096 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP013117_00096 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP013117_00097 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP013117_00098 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP013117_00098 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP013117_00098 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP013117_00100 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP013117_00101 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP013117_00101 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 CP013117_00101 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 CP013117_00101 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 CP013117_00101 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP013117_00101 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 CP013117_00102 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP013117_00102 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain GTP_EFTU PF00009.27 CP013117_00104 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP013117_00104 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP013117_00104 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP013117_00104 - 1.3e-12 47.6 0.1 2.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP013117_00104 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP013117_00104 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP013117_00104 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP013117_00104 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP013117_00104 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPT PF07931.12 CP013117_00105 - 1e-05 25.5 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CP013117_00105 - 1.5e-05 25.6 0.0 2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 CP013117_00105 - 0.016 15.6 0.0 0.073 13.4 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_33 PF13671.6 CP013117_00105 - 0.023 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain APH PF01636.23 CP013117_00106 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP013117_00106 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CP013117_00106 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 CP013117_00106 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 CP013117_00106 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 CP013117_00106 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 CP013117_00107 - 4.2e-51 174.0 0.1 4.8e-51 173.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Toprim_3 PF13362.6 CP013735_00001 - 2.4e-08 34.2 0.1 6.4e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP013735_00001 - 0.016 15.5 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP013735_00001 - 0.055 13.6 8.2 1.3 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 CP013735_00001 - 0.33 11.6 2.5 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP013735_00002 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP013735_00002 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 CP013735_00003 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 CP013735_00004 - 2.6e-30 105.7 7.7 4.2e-30 105.0 7.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CP013735_00004 - 1.6e-26 93.2 0.7 2.2e-26 92.7 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CP013735_00004 - 4.7e-06 25.6 0.7 7e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 CP013735_00004 - 0.0036 17.4 0.7 0.012 15.7 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ORC6 PF05460.13 CP013735_00004 - 0.011 15.0 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HicB_lk_antitox PF15919.5 CP013735_00006 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP013735_00006 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 CP013735_00007 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP013735_00007 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP013735_00007 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP013735_00007 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP013735_00007 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP013735_00007 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 CP013735_00008 - 0.011 15.6 0.4 0.022 14.6 0.4 1.5 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 CP013735_00010 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP013735_00010 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP013735_00010 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP013735_00010 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP013735_00011 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP013735_00011 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP013735_00013 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP013735_00013 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP013735_00014 - 7.6e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP013735_00014 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP013735_00014 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP013735_00014 - 0.038 14.1 5.5 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 CP013735_00015 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP013735_00015 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP013735_00015 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP013735_00015 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP013735_00015 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 CP013735_00016 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 CP013735_00017 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP013735_00018 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP013735_00018 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP013735_00018 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP013735_00018 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP013735_00019 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP013735_00019 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP013735_00019 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP013735_00019 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP013735_00019 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 CP013735_00019 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 CP013735_00019 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 CP013735_00019 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 CP013735_00020 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP013735_00020 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP013735_00020 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP013735_00021 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP013735_00021 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP013735_00022 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP013735_00022 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP013735_00023 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP013735_00023 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP013735_00024 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP013735_00024 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP013735_00025 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP013735_00025 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP013735_00025 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP013735_00025 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP013735_00025 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP013735_00025 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP013735_00025 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP013735_00025 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP013735_00025 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP013735_00025 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP013735_00025 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP013735_00025 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP013735_00025 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP013735_00025 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP013735_00025 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP013735_00025 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP013735_00025 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP013735_00025 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP013735_00025 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP013735_00025 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP013735_00025 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP013735_00025 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP013735_00025 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP013735_00025 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP013735_00025 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP013735_00025 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP013735_00025 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP013735_00025 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP013735_00025 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP013735_00025 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP013735_00025 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP013735_00026 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP013735_00026 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP013735_00026 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP013735_00026 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP013735_00027 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP013735_00027 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP013735_00027 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP013735_00028 - 8.4e-36 123.3 1.7 1.1e-35 122.9 1.7 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP013735_00029 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Redoxin PF08534.10 CP013735_00031 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP013735_00032 - 1.1e-97 327.7 8.1 1.6e-97 327.2 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP013735_00032 - 4.4e-12 46.1 2.6 6.4e-12 45.6 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP013735_00032 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP013735_00032 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP013735_00032 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP013735_00032 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP013735_00032 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP013735_00032 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP013735_00032 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP013735_00032 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP013735_00032 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP013735_00032 - 0.43 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP013735_00032 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP013735_00032 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP013735_00032 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP013735_00032 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP013735_00032 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP013735_00033 - 0.00012 22.0 2.7 0.00031 20.6 2.7 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP013735_00033 - 0.035 14.0 4.6 0.25 11.3 4.6 2.5 1 1 0 1 1 1 0 Intein splicing domain Ribonuc_2-5A PF06479.12 CP013735_00034 - 0.022 14.9 1.5 0.03 14.5 1.5 1.5 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF5311 PF17238.2 CP013735_00034 - 0.053 13.4 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5311) T6SS-SciN PF12790.7 CP014345_00001 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 CP014345_00002 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 CP014345_00003 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 CP014345_00004 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 CP014345_00005 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 CP014345_00005 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 CP014345_00005 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 CP014345_00005 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CP014345_00005 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 CP014345_00005 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 CP014345_00005 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 CP014345_00006 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CP014345_00006 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 CP014345_00006 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF2974 PF11187.8 CP014345_00010 - 3.9e-08 33.1 0.1 1e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CP014345_00010 - 6.3e-08 32.6 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CP014345_00010 - 3.1e-05 23.6 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CP014345_00010 - 4.2e-05 23.4 0.4 0.00085 19.1 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 CP014345_00010 - 0.00084 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CP014345_00010 - 0.0016 19.1 0.0 0.0022 18.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CP014345_00010 - 0.0033 17.4 0.1 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 CP014345_00010 - 0.036 13.6 1.9 0.045 13.3 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4450) SBDS PF01172.18 CP014345_00010 - 0.11 12.6 1.6 0.82 9.8 1.5 2.7 1 1 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Lipase_3 PF01764.25 CP014345_00012 - 1.5e-08 34.6 0.0 5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CP014345_00012 - 3.1e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 CP014345_00012 - 1.1e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CP014345_00012 - 5.6e-05 23.0 0.1 9.7e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 CP014345_00012 - 0.00041 20.0 0.1 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CP014345_00012 - 0.00064 20.4 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CP014345_00012 - 0.0014 18.6 0.3 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 CP014345_00012 - 0.014 15.3 1.8 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase NMT PF01233.19 CP014345_00012 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Hydrolase_4 PF12146.8 CP014345_00012 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CP014345_00012 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF2070 PF09843.9 CP014345_00013 - 0.082 11.2 10.5 0.094 11.0 10.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 CP014345_00013 - 0.094 13.1 17.4 0.35 11.2 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 CP014345_00013 - 0.2 11.0 22.9 4.3 6.6 6.7 2.4 1 1 1 2 2 2 0 Glucosyl transferase GtrII ABC2_membrane_5 PF13346.6 CP014345_00013 - 0.31 10.5 21.7 0.023 14.2 5.5 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF5385 PF17359.2 CP014345_00013 - 0.4 10.2 9.3 0.085 12.4 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF3784 PF12650.7 CP014345_00013 - 4.8 7.4 22.3 0.22 11.7 8.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) RseC_MucC PF04246.12 CP014345_00014 - 9.1 6.3 6.3 2.4 8.1 3.1 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AAA_31 PF13614.6 CP014345_00016 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP014345_00016 - 0.0018 18.3 0.5 0.016 15.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP014345_00016 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 CP014345_00017 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 CP014345_00017 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal OrfB_IS605 PF01385.19 CP014345_00018 - 1.8e-12 47.5 1.0 2.5e-12 47.1 1.0 1.2 1 0 0 1 1 1 1 Probable transposase AAA_25 PF13481.6 CP014345_00019 - 2.9e-15 56.3 0.0 6.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP014345_00019 - 0.00024 20.5 0.0 0.01 15.2 0.0 2.4 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP014345_00019 - 0.0012 18.6 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP014345_00019 - 0.0029 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP014345_00019 - 0.0041 16.5 0.1 0.03 13.7 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP014345_00019 - 0.053 13.9 0.8 0.67 10.4 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP014345_00019 - 0.16 12.1 0.8 0.49 10.5 0.8 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicA_toxin PF07927.12 CP014345_00020 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP014345_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Peptidase_M4_C PF02868.15 CP014345_00022 - 0.051 13.4 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain AAA_31 PF13614.6 CP014345_00025 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP014345_00025 - 0.0018 18.3 0.5 0.016 15.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP014345_00025 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 CP014345_00026 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 CP014345_00026 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal NYN PF01936.18 CP014345_00028 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 CP014345_00028 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 CP014345_00028 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain Toprim_3 PF13362.6 CP014345_00030 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP014345_00030 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP014345_00030 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 CP014345_00030 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Put_DNA-bind_N PF06971.13 CP014345_00032 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus BLOC1_2 PF10046.9 CP014345_00033 - 0.049 13.9 1.0 0.25 11.7 1.0 2.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2459 PF09601.10 CP014345_00033 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) SseC PF04888.12 CP014345_00036 - 0.005 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 CP014345_00036 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 CP014345_00036 - 0.036 14.0 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 CP014345_00036 - 0.061 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UvrA_DNA-bind PF17755.1 CP014345_00037 - 0.008 16.5 0.4 2.8 8.3 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain Glyco_tranf_2_5 PF13712.6 CP014345_00038 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 CP014345_00039 - 1.5e-38 132.9 22.2 1.5e-38 132.9 22.2 2.3 2 1 1 3 3 3 1 TraG-like protein, N-terminal region CHMI PF02962.15 CP014345_00039 - 0.0083 16.5 0.0 0.057 13.8 0.0 2.6 1 1 0 1 1 1 1 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 CP014345_00041 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 CP014345_00041 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 CP014345_00041 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 CP014345_00041 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 CP014345_00043 - 8.6e-09 35.6 0.3 0.00036 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 CP014345_00043 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 CP014345_00044 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 CP014345_00046 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 CP014345_00046 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein Pox_J1 PF03338.15 CP014345_00047 - 0.0028 17.5 1.7 0.096 12.5 0.1 2.5 2 1 0 2 2 2 2 Poxvirus J1 protein DHHA1 PF02272.19 CP014345_00047 - 0.85 10.0 3.4 1.7 9.1 3.2 1.6 1 1 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 CP014345_00048 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 CP014345_00049 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 CP014345_00049 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 CP014345_00049 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 CP014345_00051 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 CP014345_00051 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 CP014345_00052 - 7.5e-25 87.7 1.9 1.4e-24 86.8 0.2 2.2 2 1 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.8 CP014345_00052 - 0.00023 21.3 0.1 0.0011 19.2 0.1 2.2 2 0 0 2 2 2 1 IMS family HHH motif CooC_C PF15976.5 CP014345_00054 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 CP014345_00054 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 CP014345_00055 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 CP014345_00055 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 CP014345_00055 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 CP014345_00055 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 CP014345_00055 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CP014345_00055 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 CP014345_00055 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 CP014345_00055 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CP014345_00055 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CP014345_00055 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 CP014345_00055 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CP014345_00055 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 CP014345_00055 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 CP014345_00055 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 CP014345_00055 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 CP014345_00055 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 CP014345_00055 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 CP014345_00055 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 CP014345_00055 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 CP014345_00055 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 CP014345_00057 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 CP014345_00057 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Occludin_ELL PF07303.13 CP014345_00060 - 0.0057 17.4 1.0 0.0076 17.0 1.0 1.1 1 0 0 1 1 1 1 Occludin homology domain DUF2935 PF11155.8 CP014345_00060 - 0.019 15.3 1.9 0.023 15.0 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) HAUS4 PF14735.6 CP014345_00060 - 0.038 13.7 0.1 0.044 13.5 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF2207 PF09972.9 CP014345_00060 - 0.19 10.5 2.4 0.2 10.4 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_NinH PF06322.11 CP014345_00061 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein YafQ_toxin PF15738.5 CP014345_00065 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 CP014345_00065 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 CP014345_00065 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 CP014345_00065 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system WGR PF05406.15 CP014345_00070 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 CP014345_00070 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 CP014345_00071 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 CP014345_00072 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CP014345_00072 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 CP014345_00072 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 CP014345_00072 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 CP014345_00072 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 CP014345_00072 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 CP014345_00072 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Prok-TraM PF09228.10 CP014345_00074 - 0.087 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 CP014345_00074 - 2.3 8.5 10.7 0.22 11.8 0.4 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 CP014345_00075 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 CP014345_00076 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 CP014345_00076 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 CP014345_00076 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 CP014345_00078 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 CP014345_00078 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 CP014345_00080 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 CP014345_00082 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 CP014345_00082 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 CP014345_00082 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 CP014345_00084 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 CP014345_00085 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 CP014345_00085 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 CP014345_00085 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 CP014345_00085 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myc-LZ PF02344.15 CP014345_00086 - 0.045 13.9 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Myc leucine zipper domain Importin_rep PF18773.1 CP014345_00087 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 CP014345_00087 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 CP014345_00087 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 CP014345_00088 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 CP014345_00088 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 CP014345_00089 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 CP014345_00090 - 1.6e-110 370.4 0.0 1.8e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 CP014345_00091 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 CP014345_00091 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 CP014345_00091 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 CP014345_00092 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 CP014345_00092 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 CP014345_00093 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 CP014345_00093 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 CP014345_00094 - 2.9e-12 46.6 0.0 4.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 CP014345_00094 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system TetR_C_24 PF17932.1 CP014345_00094 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PX PF00787.24 CP014345_00094 - 0.28 11.2 14.0 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain Phage_portal PF04860.12 CP014569_00001 - 3.7e-29 101.9 0.1 4.8e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Phage portal protein DUF3770 PF12603.8 CP014569_00001 - 0.036 13.6 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) Terminase_6 PF03237.15 CP014569_00002 - 8.4e-17 61.6 0.0 1.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Terminase-like family Terminase_6C PF17289.2 CP014569_00002 - 1.9e-07 31.3 0.0 4.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Terminase RNaseH-like domain HTH_Tnp_1 PF01527.20 CP014569_00002 - 1.4e-06 28.5 0.2 4.1e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 CP014569_00002 - 0.00044 20.2 0.0 0.034 14.2 0.0 3.5 3 1 1 4 4 4 1 Helix-turn-helix HTH_28 PF13518.6 CP014569_00002 - 0.0027 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CP014569_00002 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 CP014569_00002 - 0.035 14.2 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CP014569_00002 - 0.061 13.1 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CP014569_00002 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Stirrup PF09061.6 CP014569_00002 - 0.11 12.7 0.0 3.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Stirrup YajC PF02699.15 CP014569_00004 - 0.044 13.7 0.0 0.045 13.6 0.0 1.0 1 0 0 1 1 1 0 Preprotein translocase subunit FeoB_associated PF12669.7 CP014569_00004 - 0.057 13.8 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Phage_Mu_F PF04233.14 CP014569_00007 - 1.2e-05 26.0 0.0 3.5e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Phage Mu protein F like protein SieB PF14163.6 CP014569_00007 - 0.065 12.7 5.5 0.023 14.2 2.0 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B TFIID_NTD2 PF04494.15 CP014569_00007 - 0.53 10.5 3.9 1 9.6 0.1 2.9 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain Zn_Tnp_IS1595 PF12760.7 CP014569_00008 - 0.0013 18.7 1.5 0.0017 18.3 1.5 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.13 CP014569_00008 - 0.0049 16.9 0.3 0.0058 16.7 0.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_KTR PF14205.6 CP014569_00008 - 0.097 12.5 5.1 0.16 11.8 5.1 1.5 1 1 0 1 1 1 0 Cysteine-rich KTR DUF1018 PF06252.12 CP014569_00009 - 0.02 15.8 0.1 0.036 15.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) OrfB_IS605 PF01385.19 CP014569_00012 - 1.2e-24 86.8 0.2 1.2e-24 86.8 0.2 2.3 2 0 0 2 2 2 1 Probable transposase OrfB_Zn_ribbon PF07282.11 CP014569_00012 - 3.3e-18 65.4 1.3 3.3e-18 65.4 1.3 1.8 2 0 0 2 2 2 1 Putative transposase DNA-binding domain VPS28 PF03997.12 CP014569_00012 - 0.051 13.3 0.4 0.051 13.3 0.4 2.4 2 1 1 3 3 3 0 VPS28 protein HTH_OrfB_IS605 PF12323.8 CP014569_00012 - 0.072 12.6 0.2 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Y1_Tnp PF01797.16 CP014569_00013 - 1.5e-38 131.6 0.0 2.3e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Transposase IS200 like DUF1353 PF07087.11 CP014569_00014 - 1.3e-18 66.4 0.0 1.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) ExsD PF16806.5 CP014569_00015 - 0.0064 16.4 1.8 0.0096 15.9 1.8 1.2 1 0 0 1 1 1 1 Antiactivator protein ExsD CBM_X2 PF03442.14 CP014569_00015 - 0.032 14.3 1.5 0.47 10.6 0.3 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain X2 YlqD PF11068.8 CP014569_00015 - 0.052 13.9 4.1 0.084 13.2 4.1 1.4 1 0 0 1 1 1 0 YlqD protein HSBP1 PF06825.12 CP014569_00015 - 0.065 13.1 0.4 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Spc7 PF08317.11 CP014569_00015 - 0.098 11.5 10.1 0.14 11.0 10.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1465 PF07323.12 CP014569_00015 - 0.11 12.4 1.1 0.18 11.6 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF1664 PF07889.12 CP014569_00015 - 0.28 11.2 4.1 0.41 10.7 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4455 PF14643.6 CP014569_00015 - 0.69 8.5 8.7 0.48 9.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) Atg14 PF10186.9 CP014569_00015 - 0.79 8.7 7.5 2 7.4 7.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 CP014569_00015 - 2.5 7.6 9.4 1.5 8.3 6.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DivIC PF04977.15 CP014569_00016 - 0.24 11.2 0.1 0.24 11.2 0.1 2.6 1 1 2 3 3 3 0 Septum formation initiator Phage_holin_3_3 PF16083.5 CP014569_00018 - 1.2e-10 41.3 4.9 1.6e-10 40.9 4.9 1.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III PG_binding_3 PF09374.10 CP014569_00019 - 2.5e-11 43.7 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Predicted Peptidoglycan domain Glyco_hydro_108 PF05838.12 CP014569_00019 - 5e-08 33.3 0.1 9.4e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase 108 MethyltransfD12 PF02086.15 CP014569_00020 - 1.3e-28 100.4 4.0 2.2e-28 99.7 4.0 1.4 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Zea_mays_MuDR PF05928.11 CP014569_00020 - 0.055 13.1 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) HTH_26 PF13443.6 CP014569_00021 - 0.0001 22.7 0.1 0.66 10.4 0.0 3.1 2 1 1 3 3 3 2 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.6 CP014569_00021 - 0.0042 17.2 0.0 1.5 9.0 0.0 3.3 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 CP014569_00021 - 0.013 15.6 1.7 6.7 6.8 0.0 3.5 3 1 1 4 4 4 0 Helix-turn-helix Phage_terminase PF10668.9 CP014569_00021 - 0.015 15.3 0.5 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Phage terminase small subunit DUF4004 PF13171.6 CP014569_00021 - 0.021 15.1 3.4 9.3 6.4 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF4004) DUF2862 PF11061.8 CP014569_00021 - 0.053 13.4 0.1 9.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) HTH_23 PF13384.6 CP014569_00021 - 0.062 13.1 0.0 24 4.9 0.0 3.3 3 1 0 3 3 3 0 Homeodomain-like domain HTH_19 PF12844.7 CP014569_00021 - 0.1 12.6 0.0 0.59 10.2 0.0 2.4 3 1 0 3 3 3 0 Helix-turn-helix domain AviRa PF11599.8 CP014569_00021 - 0.11 12.0 0.0 4 6.8 0.0 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa YcxB PF14317.6 CP014569_00021 - 0.16 11.7 2.8 4.1 7.2 0.1 2.5 2 1 0 2 2 2 0 YcxB-like protein DUF2569 PF10754.9 CP014569_00024 - 0.026 15.0 0.4 0.042 14.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) PMT_4TMC PF16192.5 CP014569_00024 - 0.06 12.9 0.3 0.083 12.5 0.3 1.2 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase NiFe_hyd_3_EhaA PF17367.2 CP014569_00024 - 0.14 12.3 3.0 0.1 12.8 1.1 1.7 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A SHE3 PF17078.5 CP014569_00025 - 0.0065 16.2 10.7 0.0078 16.0 10.7 1.0 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 F420_oxidored PF03807.17 CP014569_00025 - 0.009 16.6 0.5 0.011 16.3 0.5 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent SKIP_SNW PF02731.15 CP014569_00025 - 0.031 13.9 2.1 0.042 13.5 2.1 1.1 1 0 0 1 1 1 0 SKIP/SNW domain EutB PF06751.11 CP014569_00025 - 0.037 12.8 0.6 0.039 12.8 0.6 1.0 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) FB_lectin PF07367.11 CP014569_00025 - 0.072 13.0 0.3 0.094 12.7 0.3 1.1 1 0 0 1 1 1 0 Fungal fruit body lectin MCC-bdg_PDZ PF10506.9 CP014569_00025 - 0.13 12.3 6.4 0.078 13.0 3.1 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF737 PF05300.11 CP014569_00025 - 0.35 11.2 6.5 0.43 10.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) COX8 PF02285.15 CP014569_00027 - 0.016 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII O-antigen_lig PF13425.6 CP014569_00028 - 0.0041 16.0 3.8 0.0059 15.4 3.8 1.2 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Insulin_TMD PF17870.1 CP014569_00028 - 0.035 14.2 1.3 0.035 14.2 1.3 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment TMEM51 PF15345.6 CP014569_00028 - 0.079 12.8 0.1 0.13 12.1 0.1 1.3 1 1 0 1 1 1 0 Transmembrane protein 51 RRXRR PF14239.6 CP014569_00031 - 1.5e-55 187.8 5.1 2e-55 187.3 5.1 1.2 1 0 0 1 1 1 1 RRXRR protein HNH_5 PF14279.6 CP014569_00031 - 4e-12 45.8 1.5 7.1e-12 45.0 1.5 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 CP014569_00031 - 4.7e-09 36.3 3.1 9e-09 35.4 3.1 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 CP014569_00031 - 8.2e-09 35.2 0.1 2.4e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease DUF325 PF03804.13 CP014569_00032 - 0.17 11.9 0.9 0.36 10.9 0.3 1.9 2 0 0 2 2 2 0 Viral proteins of unknown function Yae1_N PF09811.9 CP014569_00033 - 0.41 10.4 1.9 0.6 9.9 0.7 1.7 2 0 0 2 2 2 0 Essential protein Yae1, N terminal DUF1411 PF07199.11 CP014569_00034 - 0.2 11.3 8.9 0.024 14.3 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) HdeA PF06411.11 CP014569_00035 - 0.057 13.6 0.2 0.087 13.0 0.2 1.3 1 0 0 1 1 1 0 HdeA/HdeB family FAM76 PF16046.5 CP014569_00037 - 0.24 10.7 30.5 0.067 12.5 21.6 2.0 1 1 1 2 2 2 0 FAM76 protein UCH PF00443.29 CP014569_00037 - 0.42 10.1 17.0 0.026 14.0 2.2 2.7 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF4806 PF16064.5 CP014569_00037 - 0.55 10.6 10.9 0.24 11.7 1.1 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4806) DUF4665 PF15679.5 CP014569_00037 - 2.5 8.7 34.7 1 10.0 5.6 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) Chlorosome_CsmC PF11098.8 CP014569_00038 - 0.0041 17.1 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Chlorosome envelope protein C Tup_N PF08581.10 CP014569_00038 - 0.017 15.4 1.7 0.017 15.4 1.7 3.1 1 1 1 2 2 2 0 Tup N-terminal CBP_BcsR PF10945.8 CP014569_00038 - 0.031 13.7 0.3 0.067 12.7 0.3 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Spectrin_like PF18373.1 CP014569_00038 - 0.033 14.3 3.6 0.23 11.6 0.3 3.0 1 1 2 3 3 3 0 Spectrin like domain APG6_N PF17675.1 CP014569_00038 - 0.042 14.4 6.1 0.28 11.7 0.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 CP014569_00038 - 0.059 12.6 6.3 0.097 11.9 2.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 CP014569_00038 - 0.099 12.9 2.4 0.25 11.6 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PSD3 PF07626.11 CP014569_00038 - 0.14 12.7 0.1 0.23 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) SKA2 PF16740.5 CP014569_00038 - 0.25 11.1 7.9 0.71 9.7 6.6 2.1 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 CP014569_00038 - 0.53 10.8 6.0 12 6.5 6.1 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 CP014569_00038 - 0.55 11.0 3.8 13 6.6 0.2 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2203 PF09969.9 CP014569_00038 - 1.2 9.9 4.2 10 6.9 1.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ZapB PF06005.12 CP014569_00038 - 2.7 8.5 8.5 8.5 6.9 8.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB Phasin PF05597.11 CP014569_00039 - 0.17 11.9 9.3 0.68 9.9 1.9 2.6 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF948 PF06103.11 CP014569_00039 - 0.47 10.7 5.0 2.7 8.3 0.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 CP014569_00039 - 0.47 11.1 2.2 6.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MutS_III PF05192.18 CP014569_00039 - 0.56 10.4 5.4 0.64 10.2 5.4 1.2 1 0 0 1 1 1 0 MutS domain III Bravo_FIGEY PF13882.6 CP014569_00039 - 1.2 10.5 7.1 0.61 11.5 4.1 2.0 2 0 0 2 2 2 0 Bravo-like intracellular region YtxH PF12732.7 CP014569_00039 - 2.5 8.7 21.0 0.11 13.1 2.6 3.2 3 0 0 3 3 3 0 YtxH-like protein HEPN_RES_NTD1 PF18870.1 CP014569_00039 - 4.2 7.6 8.3 7.5 6.8 0.4 3.0 1 1 1 3 3 3 0 HEPN/RES N-terminal domain 1 SLT PF01464.20 CP014569_00040 - 8.9e-12 44.7 0.0 1.4e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 Transglycosylase SLT domain Leukocidin PF07968.12 CP014569_00040 - 0.00012 22.1 0.2 0.0002 21.3 0.2 1.4 1 0 0 1 1 1 1 Leukocidin/Hemolysin toxin family Glucosaminidase PF01832.20 CP014569_00040 - 0.2 12.2 2.1 0.27 11.8 2.1 1.5 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase AAA_22 PF13401.6 CP014569_00041 - 0.14 12.4 0.0 6.7 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF226 PF02890.14 CP014569_00042 - 0.017 15.1 0.9 0.017 15.1 0.9 3.2 3 1 0 3 3 3 0 Borrelia family of unknown function DUF226 Y1_Tnp PF01797.16 CP014569_00043 - 1.5e-38 131.6 0.0 2.3e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Transposase IS200 like OrfB_IS605 PF01385.19 CP014569_00044 - 1.2e-24 86.8 0.2 1.2e-24 86.8 0.2 2.3 2 0 0 2 2 2 1 Probable transposase OrfB_Zn_ribbon PF07282.11 CP014569_00044 - 3.3e-18 65.4 1.3 3.3e-18 65.4 1.3 1.8 2 0 0 2 2 2 1 Putative transposase DNA-binding domain VPS28 PF03997.12 CP014569_00044 - 0.051 13.3 0.4 0.051 13.3 0.4 2.4 2 1 1 3 3 3 0 VPS28 protein HTH_OrfB_IS605 PF12323.8 CP014569_00044 - 0.073 12.6 0.2 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain CshA_NR2 PF18651.1 CP014569_00046 - 0.099 11.8 0.2 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Surface adhesin CshA non-repetitive domain 2 DUF3603 PF12227.8 CP014569_00048 - 0.3 10.4 3.1 0.27 10.5 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) DUF2357 PF09823.9 CP014569_00049 - 0.098 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) ThylakoidFormat PF11264.8 CP014569_00049 - 0.24 11.0 2.1 1.8 8.2 2.1 2.0 1 1 0 1 1 1 0 Thylakoid formation protein DUF4214 PF13946.6 CP014569_00051 - 0.0004 20.4 4.0 0.00042 20.3 0.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4214) DUF3784 PF12650.7 CP014569_00052 - 0.0045 17.2 0.7 0.0048 17.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3784) TMCCDC2 PF15844.5 CP014569_00052 - 0.021 14.7 0.7 0.021 14.7 0.7 1.1 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 DUF1240 PF06836.12 CP014569_00052 - 0.052 14.1 1.8 0.13 12.8 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) DUF2321 PF10083.9 CP014569_00053 - 0.05 13.2 0.1 0.053 13.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Phage_cap_P2 PF05125.12 CP014569_00058 - 9.9e-08 31.3 2.5 2e-06 27.0 2.5 2.1 1 1 0 1 1 1 1 Phage major capsid protein, P2 family Tctex-1 PF03645.13 CP014569_00058 - 0.014 15.7 1.3 0.14 12.4 0.0 2.9 2 2 0 2 2 2 0 Tctex-1 family Peptidase_S78_2 PF14550.6 CP014569_00059 - 7.4e-34 116.4 0.1 1.2e-33 115.8 0.1 1.3 1 0 0 1 1 1 1 Putative phage serine protease XkdF Holin_BhlA PF10960.8 CP014569_00059 - 0.026 14.5 1.7 0.061 13.3 1.7 1.6 1 0 0 1 1 1 0 BhlA holin family Abi_C PF14355.6 CP014569_00059 - 0.059 13.5 0.7 13 6.0 0.0 3.2 2 1 1 3 3 3 0 Abortive infection C-terminus DUF2203 PF09969.9 CP014569_00059 - 0.26 12.0 1.8 0.46 11.2 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4391 PF14335.6 CP014569_00059 - 0.29 10.8 5.2 0.66 9.6 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) SPT16 PF08644.11 CP014569_00059 - 0.58 10.3 3.5 0.87 9.8 0.8 2.4 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Prok-TraM PF09228.10 CP014743_00001 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 CP014743_00001 - 3 8.1 11.1 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 CP014743_00002 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 CP014743_00003 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 CP014743_00003 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 CP014743_00003 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 CP014743_00005 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 CP014743_00005 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 CP014743_00007 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 CP014743_00009 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 CP014743_00009 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 CP014743_00009 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 CP014743_00011 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 CP014743_00012 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 CP014743_00012 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 CP014743_00012 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 CP014743_00012 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Importin_rep PF18773.1 CP014743_00013 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 CP014743_00013 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 CP014743_00013 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 CP014743_00014 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 CP014743_00014 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 CP014743_00015 - 3.5e-47 161.1 0.0 3.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 CP014743_00016 - 2.2e-110 370.0 0.0 2.5e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 CP014743_00017 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 CP014743_00017 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 CP014743_00017 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 CP014743_00018 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 CP014743_00018 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 CP014743_00019 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 CP014743_00019 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 CP014743_00020 - 1.2e-12 47.9 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 CP014743_00020 - 0.00013 22.0 0.2 0.00079 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 CP014743_00020 - 0.0034 17.4 13.8 0.059 13.3 1.9 4.2 3 2 0 3 3 3 2 PX domain T6SS-SciN PF12790.7 CP014743_00021 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 CP014743_00022 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 CP014743_00023 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 CP014743_00024 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 CP014743_00025 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 CP014743_00025 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 CP014743_00025 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 CP014743_00025 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CP014743_00025 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 CP014743_00025 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 CP014743_00025 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 CP014743_00026 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CP014743_00026 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 CP014743_00026 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3870 PF12986.7 CP014743_00027 - 0.098 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) DUF2459 PF09601.10 CP014743_00030 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) BLOC1_2 PF10046.9 CP014743_00030 - 0.1 12.9 2.0 0.25 11.7 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_DNA-bind_N PF06971.13 CP014743_00031 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Toprim_3 PF13362.6 CP014743_00032 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP014743_00032 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP014743_00032 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 CP014743_00032 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold NYN PF01936.18 CP014743_00034 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 CP014743_00034 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 CP014743_00034 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain PTS-HPr PF00381.19 CP014743_00035 - 0.17 12.1 0.0 0.19 12.0 0.0 1.0 1 0 0 1 1 1 0 PTS HPr component phosphorylation site RHH_7 PF16777.5 CP014743_00036 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 CP014743_00036 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 CP014743_00037 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP014743_00037 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP014743_00037 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 CP014743_00037 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP014743_00038 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP014743_00038 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP014743_00039 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP014743_00039 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP014743_00039 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP014743_00039 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP014743_00039 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP014743_00040 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP014743_00040 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP014743_00040 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP014743_00040 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP014743_00040 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP014743_00040 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP014743_00040 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 CP014743_00041 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 CP014743_00042 - 0.047 13.8 0.3 4.4 7.5 0.0 2.3 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 CP014743_00043 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP014743_00043 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Asp-B-Hydro_N PF05279.11 CP014743_00045 - 2.9 7.9 12.2 3.4 7.7 12.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GTP_EFTU PF00009.27 CP014743_00046 - 8.1e-59 198.4 0.4 1.1e-58 198.0 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP014743_00046 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP014743_00046 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP014743_00046 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP014743_00046 - 1.8e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP014743_00046 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP014743_00046 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP014743_00046 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP014743_00046 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 CP014743_00048 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP014743_00048 - 0.022 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 CP014743_00049 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP014743_00049 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP014743_00049 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP014743_00049 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP014743_00049 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP014743_00049 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP014743_00049 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP014743_00049 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP014743_00049 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP014743_00049 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP014743_00049 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP014743_00049 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP014743_00049 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP014743_00049 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP014743_00049 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP014743_00049 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP014743_00049 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 CP014743_00050 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP014743_00051 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP014743_00051 - 0.077 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP014743_00051 - 0.74 9.8 5.2 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CP014743_00052 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP014743_00053 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP014743_00053 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP014743_00053 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP014743_00053 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CP014743_00054 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP014743_00054 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP014743_00054 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP014743_00054 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Phage_pRha PF09669.10 CP014743_00055 - 3.4e-21 75.6 0.1 3.4e-21 75.6 0.1 2.0 2 1 0 2 2 2 1 Phage regulatory protein Rha (Phage_pRha) T2SSE PF00437.20 CP014743_00056 - 6.4e-54 182.8 0.0 7.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP014743_00056 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP014743_00056 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP014743_00056 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP014743_00056 - 0.0014 18.9 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP014743_00056 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP014743_00056 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP014743_00056 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP014743_00056 - 0.0049 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP014743_00056 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP014743_00056 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP014743_00056 - 0.0088 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP014743_00056 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP014743_00056 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP014743_00056 - 0.022 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP014743_00056 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP014743_00056 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP014743_00056 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP014743_00056 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP014743_00056 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP014743_00056 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP014743_00056 - 0.039 13.2 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP014743_00056 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP014743_00056 - 0.063 11.9 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP014743_00056 - 0.065 13.6 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP014743_00056 - 0.085 12.8 0.4 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP014743_00056 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP014743_00056 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP014743_00056 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP014743_00056 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP014743_00056 - 0.29 11.6 3.1 0.32 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CP014743_00057 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP014743_00057 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CP014743_00058 - 6.2e-55 186.2 1.7 1e-54 185.5 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP014743_00058 - 0.082 12.7 0.3 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 CP014743_00059 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP014743_00059 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CP014743_00060 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP014743_00060 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CP014743_00061 - 2.7e-29 102.5 30.5 2.7e-29 102.5 30.5 1.5 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP014743_00061 - 0.21 11.4 1.5 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered T4SS PF07996.11 CP014743_00062 - 1.9e-28 100.2 13.4 2.7e-28 99.7 13.4 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP014743_00062 - 0.0072 16.4 1.8 0.021 15.0 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP014743_00062 - 0.0092 16.7 6.0 0.0092 16.7 6.0 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 CP014743_00062 - 0.072 13.8 1.0 0.072 13.8 1.0 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 CP014743_00062 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 CP014743_00062 - 2.3 8.7 8.3 9.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) WXG100 PF06013.12 CP014743_00062 - 7.2 6.9 12.9 1 9.7 0.7 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG IF2_N PF04760.15 CP014743_00063 - 6.5e-05 22.7 5.8 0.00049 19.9 2.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HTH_16 PF12645.7 CP014743_00063 - 0.013 15.5 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP014743_00063 - 0.029 15.1 0.5 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor FliG_N PF14842.6 CP014743_00063 - 0.039 14.5 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain SSB PF00436.25 CP014743_00064 - 2.5e-24 85.3 0.1 3.2e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family FapA PF03961.13 CP014743_00065 - 0.072 11.7 13.7 0.0066 15.1 7.2 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3251 PF11622.8 CP014743_00065 - 0.085 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Fib_alpha PF08702.10 CP014743_00065 - 1.1 9.4 11.4 0.062 13.5 3.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 CP014743_00065 - 1.8 8.9 13.9 1 9.7 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP014743_00065 - 4.4 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Ax_dynein_light PF10211.9 CP014743_00065 - 4.5 7.2 15.1 0.051 13.5 3.7 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain Phage_pRha PF09669.10 CP014743_00066 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) CagE_TrbE_VirB PF03135.14 CP014743_00067 - 9.3e-49 166.3 0.3 2.3e-48 165.0 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP014743_00067 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP014743_00067 - 1.5e-07 30.7 0.8 3.5e-07 29.5 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP014743_00067 - 0.039 14.0 5.4 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 CP014743_00068 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP014743_00068 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP014743_00070 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP014743_00070 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 CP014743_00071 - 9.1e-32 110.2 0.6 1.2e-31 109.8 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP014743_00071 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP014743_00071 - 0.065 13.3 4.7 0.68 10.0 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP014743_00071 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 CP014743_00072 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP014743_00072 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP014743_00072 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 CP014743_00072 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CP014743_00072 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP014743_00072 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 CP014743_00072 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicA_toxin PF07927.12 CP014743_00073 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP014743_00074 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CP014743_00075 - 0.0043 17.1 1.7 0.0054 16.8 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 CP014743_00075 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 CP014743_00076 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP014743_00076 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 CP014743_00077 - 2.1e-08 34.4 0.0 4.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP014743_00077 - 0.088 12.8 0.8 0.37 10.8 0.3 2.3 2 0 0 2 2 2 0 PAZ domain 5_3_exonuc PF01367.20 CP014743_00077 - 0.17 12.5 4.7 0.89 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 CP014743_00078 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 CP014743_00080 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP014743_00080 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP014743_00080 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CP014743_00081 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP014743_00081 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP014743_00081 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP014743_00081 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP014743_00081 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 CP014743_00082 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 CP014743_00083 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CP014743_00083 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CP014743_00083 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CP014743_00083 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CP014743_00083 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP014743_00083 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 CP014743_00083 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 CP014743_00083 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 CP014743_00083 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 CP014743_00083 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 CP014743_00083 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CP014743_00083 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 CP014743_00083 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 CP014743_00083 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain SNF2_N PF00176.23 CP014743_00084 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP014743_00084 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP014743_00084 - 9.4e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP014743_00084 - 1.3e-05 25.0 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP014743_00084 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP014743_00085 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 CP014743_00086 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP014743_00086 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP014743_00086 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase NnrS PF05940.12 CP014743_00088 - 0.023 14.1 9.9 0.028 13.8 9.9 1.0 1 0 0 1 1 1 0 NnrS protein DUF2070 PF09843.9 CP014743_00088 - 0.054 11.8 13.4 0.063 11.6 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 CP014743_00088 - 0.15 12.4 19.9 0.53 10.7 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 CP014743_00088 - 0.51 9.7 27.0 0.49 9.7 7.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF5385 PF17359.2 CP014743_00088 - 0.52 9.8 9.3 0.099 12.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NVEALA PF14055.6 CP014743_00088 - 4.1 7.4 6.4 4.2 7.4 0.2 2.9 1 1 2 3 3 3 0 NVEALA protein TssN PF17555.2 CP014743_00088 - 4.7 6.5 20.7 5.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2663 PF10864.8 CP014743_00088 - 6.7 7.1 10.9 36 4.8 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Lipase_3 PF01764.25 CP014743_00089 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CP014743_00089 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 CP014743_00089 - 2.7e-05 24.0 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CP014743_00089 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 CP014743_00089 - 0.00045 19.9 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CP014743_00089 - 0.0017 19.0 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CP014743_00089 - 0.0021 18.1 0.9 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 CP014743_00089 - 0.016 14.8 0.1 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF1257 PF06868.11 CP014743_00089 - 0.24 11.7 2.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) SBDS PF01172.18 CP014743_00089 - 0.79 9.8 5.3 0.83 9.8 1.4 3.2 2 2 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein SseC PF04888.12 CP014743_00092 - 0.0012 18.5 0.2 0.0032 17.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family APOBEC_C PF05240.14 CP014743_00092 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ThrE PF06738.12 CP014743_00092 - 0.019 14.3 0.8 0.051 12.9 0.8 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 CP014743_00092 - 0.033 14.1 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone PTS_EIIC_2 PF13303.6 CP014743_00092 - 0.037 13.1 1.0 0.064 12.3 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC TPR_11 PF13414.6 CP014743_00092 - 0.064 12.9 0.3 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 TPR repeat Glyco_tranf_2_5 PF13712.6 CP014743_00094 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 CP014743_00095 - 3.3e-42 144.9 22.9 3.3e-42 144.9 22.9 2.2 2 1 0 2 2 2 1 TraG-like protein, N-terminal region CHMI PF02962.15 CP014743_00095 - 0.017 15.5 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 CP014743_00098 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 CP014743_00098 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 CP014743_00098 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 CP014743_00098 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 CP014743_00100 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 CP014743_00100 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 CP014743_00101 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 CP014743_00102 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 CP014743_00102 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein DHHA1 PF02272.19 CP014743_00103 - 0.18 12.2 1.6 0.37 11.2 1.6 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 CP014743_00104 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 CP014743_00105 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 CP014743_00105 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 CP014743_00105 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 CP014743_00107 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 CP014743_00107 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 CP014743_00109 - 1.5e-25 89.9 0.2 4e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family CooC_C PF15976.5 CP014743_00110 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 CP014743_00110 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 CP014743_00111 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 CP014743_00111 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 CP014743_00111 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 CP014743_00111 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 CP014743_00111 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CP014743_00111 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 CP014743_00111 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 CP014743_00111 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CP014743_00111 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CP014743_00111 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 CP014743_00111 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CP014743_00111 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 CP014743_00111 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 CP014743_00111 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 CP014743_00111 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 CP014743_00111 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 CP014743_00111 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 CP014743_00111 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 CP014743_00111 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 CP014743_00111 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 CP014743_00113 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 CP014743_00113 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HSBP1 PF06825.12 CP014743_00115 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 CP014743_00115 - 0.026 14.9 0.3 0.039 14.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 CP014743_00115 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 CP014743_00115 - 0.11 12.8 0.3 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_NinH PF06322.11 CP014743_00116 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein WGR PF05406.15 CP014743_00120 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 CP014743_00120 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 CP014743_00121 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 CP014743_00122 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CP014743_00122 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 CP014743_00122 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 CP014743_00122 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 CP014743_00122 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 CP014743_00122 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 CP014743_00122 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Prok-TraM PF09228.10 CP014745_00001 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 CP014745_00001 - 3 8.1 11.1 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 CP014745_00003 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 CP014745_00004 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 CP014745_00004 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 CP014745_00004 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 CP014745_00006 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 CP014745_00006 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 CP014745_00008 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 DivIC PF04977.15 CP014745_00009 - 0.0039 16.9 0.2 0.0039 16.9 0.2 3.7 4 0 0 4 4 4 1 Septum formation initiator HTH_48 PF17906.1 CP014745_00009 - 0.043 13.9 0.2 5.5 7.2 0.0 3.0 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Nucleoside_tran PF01733.18 CP014745_00011 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 CP014745_00011 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 CP014745_00011 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 CP014745_00013 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 CP014745_00014 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 CP014745_00014 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 CP014745_00014 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 CP014745_00014 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Importin_rep PF18773.1 CP014745_00015 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 CP014745_00015 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 CP014745_00015 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 CP014745_00016 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 CP014745_00016 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 CP014745_00017 - 3.5e-47 161.1 0.0 3.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 CP014745_00018 - 1.6e-110 370.4 0.0 1.8e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 CP014745_00019 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 CP014745_00019 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 CP014745_00019 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 CP014745_00020 - 1.2e-169 564.6 0.0 1.4e-169 564.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 CP014745_00020 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 CP014745_00021 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 CP014745_00021 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 CP014745_00022 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 CP014745_00022 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 CP014745_00022 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 CP014745_00022 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 CP014745_00023 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 CP014745_00024 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 CP014745_00025 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 CP014745_00026 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 CP014745_00027 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 CP014745_00027 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 CP014745_00027 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 CP014745_00027 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CP014745_00027 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 CP014745_00027 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 CP014745_00027 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 CP014745_00028 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CP014745_00028 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 CP014745_00028 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3870 PF12986.7 CP014745_00029 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Syntaxin-6_N PF09177.11 CP014745_00030 - 6.8 7.3 10.5 44 4.7 3.3 4.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF2459 PF09601.10 CP014745_00031 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) BLOC1_2 PF10046.9 CP014745_00031 - 0.1 12.9 2.0 0.25 11.7 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_DNA-bind_N PF06971.13 CP014745_00032 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Toprim_3 PF13362.6 CP014745_00033 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP014745_00033 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP014745_00033 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 CP014745_00033 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 CP014745_00034 - 0.26 11.3 4.3 0.56 10.2 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) NYN PF01936.18 CP014745_00035 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 CP014745_00035 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 CP014745_00035 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain RHH_7 PF16777.5 CP014745_00037 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 CP014745_00037 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 CP014745_00038 - 4.8e-05 23.3 0.6 0.00095 19.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP014745_00038 - 0.00043 20.3 0.7 0.0043 17.1 0.7 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP014745_00038 - 0.036 13.5 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP014745_00038 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP014745_00038 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP014745_00039 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP014745_00039 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP014745_00040 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP014745_00040 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP014745_00040 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP014745_00040 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP014745_00040 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP014745_00041 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP014745_00041 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP014745_00041 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP014745_00041 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP014745_00041 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP014745_00041 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP014745_00041 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain GTP_EFTU PF00009.27 CP014745_00042 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP014745_00042 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP014745_00042 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP014745_00042 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP014745_00042 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP014745_00042 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP014745_00042 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP014745_00042 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP014745_00042 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 CP014745_00044 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP014745_00044 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 CP014745_00045 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP014745_00045 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP014745_00045 - 1.7e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP014745_00045 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP014745_00045 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP014745_00045 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CP014745_00045 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP014745_00045 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 CP014745_00045 - 0.088 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 CP014745_00045 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP014745_00045 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP014745_00045 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP014745_00045 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP014745_00045 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP014745_00045 - 6.9 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP014745_00045 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 CP014745_00046 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP014745_00047 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP014745_00047 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP014745_00047 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 CP014745_00048 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP014745_00049 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP014745_00049 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP014745_00049 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP014745_00049 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 CP014745_00050 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP014745_00050 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP014745_00050 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP014745_00050 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 CP014745_00051 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP014745_00051 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP014745_00051 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP014745_00051 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP014745_00051 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP014745_00051 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP014745_00051 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP014745_00051 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP014745_00051 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP014745_00051 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP014745_00051 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP014745_00051 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP014745_00051 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP014745_00051 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP014745_00051 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP014745_00051 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP014745_00051 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP014745_00051 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP014745_00051 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP014745_00051 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP014745_00051 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP014745_00051 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP014745_00051 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP014745_00051 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP014745_00051 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP014745_00051 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP014745_00051 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP014745_00051 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP014745_00051 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP014745_00051 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP014745_00051 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CP014745_00052 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP014745_00052 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CP014745_00053 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP014745_00053 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 CP014745_00054 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP014745_00054 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CP014745_00055 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP014745_00055 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CP014745_00056 - 2.7e-31 109.0 32.0 2.7e-31 109.0 32.0 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein DUF3176 PF11374.8 CP014745_00056 - 0.088 13.0 0.5 0.088 13.0 0.5 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF3176) T_cell_tran_alt PF15128.6 CP014745_00056 - 0.18 11.6 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP014745_00056 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 CP014745_00057 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP014745_00057 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP014745_00057 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP014745_00057 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP014745_00057 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 CP014745_00057 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 CP014745_00057 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 CP014745_00057 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 CP014745_00058 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP014745_00058 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP014745_00058 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP014745_00058 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CP014745_00059 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 CP014745_00060 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP014745_00060 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP014745_00060 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP014745_00060 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP014745_00060 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP014745_00060 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 CP014745_00061 - 6.6e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP014745_00061 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 CP014745_00061 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) CagE_TrbE_VirB PF03135.14 CP014745_00062 - 4e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP014745_00062 - 3.7e-21 75.1 1.1 6.4e-21 74.4 1.1 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP014745_00062 - 4.4e-07 29.2 0.5 1e-06 28.0 0.5 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP014745_00062 - 0.0092 16.1 2.9 1.7 8.7 0.0 3.8 4 1 1 5 5 5 2 Helicase HerA, central domain TrbC PF04956.13 CP014745_00063 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP014745_00063 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP014745_00065 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 CRISPR associated protein Cas2 Resolvase PF00239.21 CP014745_00066 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP014745_00066 - 0.026 14.3 0.7 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP014745_00066 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_25 PF13481.6 CP014745_00067 - 1.6e-14 54.0 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP014745_00067 - 0.00038 19.9 0.0 0.0018 17.6 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP014745_00067 - 0.0023 17.7 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP014745_00067 - 0.0089 15.4 0.0 0.058 12.7 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP014745_00067 - 0.009 16.4 0.2 0.22 11.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP014745_00067 - 0.16 12.0 1.6 0.74 9.9 1.6 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP014745_00067 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicB_lk_antitox PF15919.5 CP014745_00068 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system UBA_6 PF18039.1 CP014745_00069 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 CP014745_00069 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 CP014745_00069 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 CP014745_00069 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 CP014745_00070 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP014745_00070 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 CP014745_00071 - 2.5e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP014745_00071 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP014745_00071 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP014745_00071 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 CP014745_00072 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) HisK_sensor PF18698.1 CP014745_00073 - 0.052 13.9 1.6 0.072 13.5 1.6 1.3 1 1 0 1 1 1 0 Histidine kinase sensor domain SANT_DAMP1_like PF16282.5 CP014745_00074 - 0.08 13.1 0.3 0.11 12.6 0.3 1.5 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Sds3 PF08598.11 CP014745_00075 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP014745_00075 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP014745_00075 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CP014745_00076 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP014745_00076 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP014745_00076 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP014745_00076 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP014745_00076 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 CP014745_00077 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 CP014745_00078 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CP014745_00078 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CP014745_00078 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CP014745_00078 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CP014745_00078 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP014745_00078 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 CP014745_00078 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 CP014745_00078 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 CP014745_00078 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 CP014745_00078 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 CP014745_00078 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CP014745_00078 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 CP014745_00078 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 CP014745_00078 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain SNF2_N PF00176.23 CP014745_00079 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP014745_00079 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP014745_00079 - 9.4e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP014745_00079 - 1.3e-05 25.0 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP014745_00079 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP014745_00080 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 CP014745_00081 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP014745_00081 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP014745_00081 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase NnrS PF05940.12 CP014745_00083 - 0.023 14.1 9.9 0.028 13.8 9.9 1.0 1 0 0 1 1 1 0 NnrS protein DUF2070 PF09843.9 CP014745_00083 - 0.054 11.8 13.4 0.063 11.6 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 CP014745_00083 - 0.15 12.4 19.9 0.53 10.7 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 CP014745_00083 - 0.51 9.7 27.0 0.49 9.7 7.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF5385 PF17359.2 CP014745_00083 - 0.52 9.8 9.3 0.099 12.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NVEALA PF14055.6 CP014745_00083 - 4.1 7.4 6.4 4.2 7.4 0.2 2.9 1 1 2 3 3 3 0 NVEALA protein TssN PF17555.2 CP014745_00083 - 4.7 6.5 20.7 5.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2663 PF10864.8 CP014745_00083 - 6.7 7.1 10.9 36 4.8 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Lipase_3 PF01764.25 CP014745_00084 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CP014745_00084 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 CP014745_00084 - 2.7e-05 24.0 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CP014745_00084 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 CP014745_00084 - 0.00045 19.9 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CP014745_00084 - 0.0017 19.0 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CP014745_00084 - 0.0021 18.1 0.9 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 CP014745_00084 - 0.016 14.8 0.1 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF1257 PF06868.11 CP014745_00084 - 0.24 11.7 2.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) SBDS PF01172.18 CP014745_00084 - 0.79 9.8 5.3 0.83 9.8 1.4 3.2 2 2 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein SseC PF04888.12 CP014745_00087 - 0.0012 18.5 0.2 0.0032 17.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family APOBEC_C PF05240.14 CP014745_00087 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ThrE PF06738.12 CP014745_00087 - 0.019 14.3 0.8 0.051 12.9 0.8 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 CP014745_00087 - 0.033 14.1 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone PTS_EIIC_2 PF13303.6 CP014745_00087 - 0.037 13.1 1.0 0.064 12.3 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC TPR_11 PF13414.6 CP014745_00087 - 0.064 12.9 0.3 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 TPR repeat Glyco_tranf_2_5 PF13712.6 CP014745_00089 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 CP014745_00090 - 3.3e-42 144.9 22.9 3.3e-42 144.9 22.9 2.2 2 1 0 2 2 2 1 TraG-like protein, N-terminal region CHMI PF02962.15 CP014745_00090 - 0.017 15.5 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 CP014745_00093 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 CP014745_00093 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 CP014745_00093 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 CP014745_00093 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 CP014745_00095 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 CP014745_00095 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 CP014745_00096 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 CP014745_00097 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 CP014745_00097 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein DHHA1 PF02272.19 CP014745_00098 - 0.18 12.2 1.6 0.37 11.2 1.6 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 CP014745_00099 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 CP014745_00100 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 CP014745_00100 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 CP014745_00100 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 CP014745_00102 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 CP014745_00102 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 CP014745_00104 - 1.5e-25 89.9 0.2 4e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family CooC_C PF15976.5 CP014745_00105 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 CP014745_00105 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 CP014745_00106 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 CP014745_00106 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 CP014745_00106 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 CP014745_00106 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 CP014745_00106 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CP014745_00106 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 CP014745_00106 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 CP014745_00106 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CP014745_00106 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CP014745_00106 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 CP014745_00106 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CP014745_00106 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 CP014745_00106 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 CP014745_00106 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 CP014745_00106 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 CP014745_00106 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 CP014745_00106 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 CP014745_00106 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 CP014745_00106 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 CP014745_00106 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 CP014745_00108 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 CP014745_00108 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HSBP1 PF06825.12 CP014745_00110 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 CP014745_00110 - 0.026 14.9 0.3 0.039 14.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 CP014745_00110 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 CP014745_00110 - 0.11 12.8 0.3 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_NinH PF06322.11 CP014745_00111 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein WGR PF05406.15 CP014745_00115 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 CP014745_00115 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 CP014745_00116 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 CP014745_00117 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CP014745_00117 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 CP014745_00117 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 CP014745_00117 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 CP014745_00117 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 CP014745_00117 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 CP014745_00117 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator IMS PF00817.20 CP017026_00001 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family DUF4368 PF14287.6 CP017026_00002 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 CP017026_00002 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.4 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 CP017026_00002 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 CP017026_00002 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 CP017026_00002 - 0.14 12.2 0.7 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Snapin_Pallidin PF14712.6 CP017026_00002 - 1.2 9.6 6.0 13 6.3 0.2 2.9 3 0 0 3 3 3 0 Snapin/Pallidin TnpV PF14198.6 CP017026_00003 - 3.3e-41 139.8 0.5 3.6e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV AAA_18 PF13238.6 CP017026_00004 - 1.4e-14 54.8 0.0 1.8e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CP017026_00004 - 2.8e-11 43.8 0.0 3.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CP017026_00004 - 1.9e-10 40.9 0.0 3.6e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 CP017026_00004 - 1.5e-07 30.9 0.1 3.2e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 CP017026_00004 - 4e-06 27.2 0.2 1.1e-05 25.7 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 CP017026_00004 - 7.9e-06 26.3 0.0 5.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CP017026_00004 - 9.5e-06 26.1 0.0 4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CP017026_00004 - 1.5e-05 25.3 0.0 5.9e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CP017026_00004 - 6.5e-05 23.0 0.0 9.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CP017026_00004 - 0.00031 21.2 0.0 0.00041 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 CP017026_00004 - 0.001 18.4 0.2 0.0012 18.2 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 CP017026_00004 - 0.0016 17.9 0.1 0.0038 16.7 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_19 PF13245.6 CP017026_00004 - 0.0017 18.7 0.2 0.0035 17.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 CP017026_00004 - 0.0019 17.9 0.4 0.004 16.9 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CP017026_00004 - 0.0023 17.7 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CP017026_00004 - 0.0025 18.3 0.1 0.003 18.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 CP017026_00004 - 0.0033 17.4 0.4 1 9.2 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 CP017026_00004 - 0.0047 16.8 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase TIP49 PF06068.13 CP017026_00004 - 0.0054 16.0 0.4 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 CP017026_00004 - 0.0068 15.8 1.2 0.016 14.6 0.1 2.0 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 CP017026_00004 - 0.01 15.2 1.0 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 CP017026_00004 - 0.011 14.9 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 CP017026_00004 - 0.016 14.9 0.1 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 CP017026_00004 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CP017026_00004 - 0.018 15.0 0.6 0.036 14.0 0.2 1.7 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 CP017026_00004 - 0.018 14.8 0.1 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CP017026_00004 - 0.02 14.5 0.3 0.071 12.7 0.1 2.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 CP017026_00004 - 0.024 14.8 0.2 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.15 CP017026_00004 - 0.033 14.1 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 CP017026_00004 - 0.038 13.2 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ArsA_ATPase PF02374.15 CP017026_00004 - 0.04 13.1 0.1 0.099 11.8 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase MKT1_N PF12247.8 CP017026_00004 - 0.042 14.2 0.0 0.097 13.0 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Hydin_ADK PF17213.3 CP017026_00004 - 0.043 14.1 1.2 0.054 13.8 0.2 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 CP017026_00004 - 0.048 13.6 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 CP017026_00004 - 0.051 13.4 1.5 0.1 12.4 1.5 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CP017026_00004 - 0.051 14.0 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 CP017026_00004 - 0.055 13.2 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GvpD PF07088.11 CP017026_00004 - 0.057 12.0 0.4 0.41 9.2 0.1 2.1 2 1 0 2 2 2 0 GvpD gas vesicle protein AAA_7 PF12775.7 CP017026_00004 - 0.059 12.9 0.2 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 CP017026_00004 - 0.079 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 CP017026_00004 - 0.08 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 CP017026_00004 - 0.086 12.5 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase1 PF18748.1 CP017026_00004 - 0.1 12.1 0.1 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 IPT PF01745.16 CP017026_00004 - 0.11 11.9 0.2 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 Isopentenyl transferase Ploopntkinase3 PF18751.1 CP017026_00004 - 0.12 12.2 0.4 0.4 10.6 0.0 2.0 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 APH PF01636.23 CP017026_00005 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP017026_00005 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CP017026_00005 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 CP017026_00005 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 CP017026_00005 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 CP017026_00005 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 CP017026_00006 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 CP017026_00007 - 6.8e-11 42.6 0.0 8.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP017026_00007 - 0.014 14.6 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase CPT PF07931.12 CP017026_00008 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CP017026_00008 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CP017026_00008 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 CP017026_00008 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 CP017026_00008 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3847 PF12958.7 CP017026_00009 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 CP017026_00009 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 CP017026_00009 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 CP017026_00009 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MobA_MobL PF03389.15 CP017026_00010 - 3.7e-79 265.5 0.0 1.4e-78 263.6 0.0 1.9 2 0 0 2 2 2 1 MobA/MobL family Spectrin PF00435.21 CP017026_00010 - 0.015 15.8 2.4 0.18 12.3 0.2 2.9 2 1 0 2 2 2 0 Spectrin repeat Prominin PF05478.11 CP017026_00010 - 0.02 12.9 1.9 0.029 12.4 1.9 1.2 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.6 CP017026_00010 - 0.021 15.2 2.0 0.059 13.8 0.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF2408 PF10303.9 CP017026_00010 - 0.032 14.8 2.4 0.06 13.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 CP017026_00010 - 0.065 13.5 2.3 6.6 7.1 0.3 3.5 4 0 0 4 4 4 0 Tup N-terminal Mod_r PF07200.13 CP017026_00010 - 0.65 10.1 8.1 0.62 10.2 0.4 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SOAR PF16533.5 CP017026_00010 - 1.2 9.1 5.4 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region DUF4407 PF14362.6 CP017026_00010 - 5.1 6.4 8.4 53 3.0 8.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_25 PF13481.6 CP017026_00011 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 CP017026_00011 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 CP017026_00011 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 CP017026_00011 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 CP017026_00011 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 CP017026_00011 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 CP017026_00011 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CP017026_00011 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 CP017026_00011 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 CP017026_00011 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 CP017026_00011 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 CP017026_00011 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 CP017026_00011 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CP017026_00011 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 CP017026_00011 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 CP017026_00011 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 CP017026_00011 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IMS_C PF11799.8 CP017026_00012 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CP017026_00012 - 0.0002 21.5 0.0 0.00067 19.8 0.1 1.9 2 0 0 2 2 2 1 IMS family HHH motif Cob_adeno_trans PF01923.18 CP017026_00015 - 0.014 15.6 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3825 PF12873.7 CP017026_00016 - 4.2e-29 101.7 0.3 6.7e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF4795 PF16043.5 CP017026_00017 - 0.026 14.1 0.1 0.043 13.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SGT1 PF07093.11 CP017026_00018 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 CP017026_00018 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 CP017026_00018 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5309 PF17236.2 CP017026_00019 - 3e-05 23.5 0.5 3.3e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5309) HicA_toxin PF07927.12 CP017026_00020 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP017026_00021 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 CP017026_00021 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ParE_toxin PF05016.15 CP017026_00023 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 CP017026_00025 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF4131 PF13567.6 CP017026_00026 - 0.00082 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 CP017026_00026 - 0.014 15.3 3.1 0.018 15.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 CP017026_00026 - 0.055 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2721 PF11026.8 CP017026_00026 - 0.068 13.1 3.9 0.085 12.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2663 PF10864.8 CP017026_00026 - 0.13 12.7 1.9 0.16 12.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) TraG_N PF07916.11 CP017026_00027 - 3e-39 135.2 20.8 3e-39 135.2 20.8 3.2 3 1 0 4 4 4 1 TraG-like protein, N-terminal region Glyco_tranf_2_5 PF13712.6 CP017026_00028 - 0.0018 18.0 4.5 0.0035 17.1 4.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family UvrA_DNA-bind PF17755.1 CP017026_00029 - 0.0008 19.7 0.3 0.33 11.3 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 CP017026_00030 - 0.003 17.9 0.2 2.1 8.7 0.1 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain Ank_2 PF12796.7 CP017026_00033 - 1.4e-11 44.8 0.4 1.1e-06 29.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CP017026_00033 - 5.4e-10 38.6 0.4 0.0094 16.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CP017026_00033 - 0.0016 19.0 0.1 0.32 11.6 0.0 3.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CP017026_00033 - 0.0035 17.7 0.0 17 6.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CP017026_00033 - 0.016 15.5 0.1 1.6 9.1 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 CP017026_00034 - 1.6e-07 31.5 0.0 1.6e-07 31.5 0.0 3.3 2 1 0 2 2 2 1 Restriction endonuclease fold toxin 7 Ank_2 PF12796.7 CP017026_00035 - 1.6e-14 54.2 0.1 1.5e-08 35.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CP017026_00035 - 6.1e-10 38.5 0.0 0.00093 19.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CP017026_00035 - 8.6e-06 26.2 0.0 0.0017 18.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CP017026_00035 - 3.4e-05 24.1 0.0 2.5 8.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CP017026_00035 - 0.0018 18.6 0.3 0.13 12.6 0.0 3.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) APG17 PF04108.12 CP017026_00035 - 0.017 14.2 0.7 0.024 13.8 0.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF2345 PF10106.9 CP017026_00036 - 0.0046 16.8 2.2 0.016 15.1 2.2 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF3540 PF12059.8 CP017026_00036 - 0.029 14.2 0.9 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Gp5_C PF06715.12 CP017026_00036 - 0.094 12.9 0.1 0.094 12.9 0.1 4.7 3 1 2 5 5 5 0 Gp5 C-terminal repeat (3 copies) Bacteriocin_IIc PF10439.9 CP017026_00037 - 0.0019 18.2 10.8 0.0019 18.2 10.8 1.8 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 CP017026_00037 - 0.04 13.9 10.0 0.084 12.9 10.0 1.4 1 0 0 1 1 1 0 Glycine zipper DUF3482 PF11981.8 CP017026_00037 - 0.1 12.0 1.3 0.21 11.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_YMGG PF13441.6 CP017026_00037 - 0.17 11.6 8.3 0.36 10.6 8.3 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 CP017026_00037 - 1.4 8.9 12.1 2.7 7.9 12.1 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1269 PF06897.12 CP017026_00037 - 5.8 7.3 7.3 13 6.1 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Phage_GPD PF05954.11 CP017026_00039 - 5.4e-18 65.3 0.0 8.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 CP017026_00039 - 0.11 12.1 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 CP017026_00040 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 CP017026_00041 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 CP017026_00042 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 CP017026_00042 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 CP017026_00042 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 CP017026_00043 - 1e-169 564.9 0.0 1.2e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 CP017026_00043 - 0.096 12.7 0.8 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 CP017026_00044 - 1.2e-51 174.6 3.8 1.3e-51 174.4 3.8 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 CP017026_00044 - 0.082 11.5 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 CP017026_00045 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 CP017026_00045 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 CP017026_00045 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 CP017026_00045 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 CP017026_00046 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 CP017026_00047 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 CP017026_00048 - 1.1e-34 120.0 0.0 1.2e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 CP017026_00049 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 CP017026_00050 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 CP017026_00050 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 CP017026_00050 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 CP017026_00050 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CP017026_00050 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 CP017026_00050 - 0.0033 17.1 5.0 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 CP017026_00050 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 CP017026_00051 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CP017026_00051 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 CP017026_00051 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain Y1_Tnp PF01797.16 CP017026_00054 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 CP017026_00055 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 CP017026_00055 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 CP017026_00055 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 CP017026_00055 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 CP017026_00055 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 CP017026_00055 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 CP017026_00055 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 CP017026_00055 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 CP017026_00055 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 CP017026_00056 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 CP017026_00056 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 CP017026_00057 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 CP017026_00058 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 CP017026_00058 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 CP017026_00058 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 CP017026_00058 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 CP017026_00058 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 CP017026_00058 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 CP017026_00058 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 CP017026_00058 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 CP017026_00058 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 CP017026_00059 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 CP017026_00059 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 CP017026_00060 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 CP017026_00061 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 CP017026_00061 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 CP017026_00061 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 CP017026_00061 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 CP017026_00061 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 CP017026_00061 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 CP017026_00061 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 CP017026_00061 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 CP017026_00061 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3492 PF11997.8 CP017026_00062 - 0.19 11.4 2.9 0.5 10.1 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CLZ PF16526.5 CP017026_00062 - 0.99 9.8 4.8 11 6.5 0.2 3.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MeMO_Hyd_G PF02964.16 CP017026_00063 - 0.078 13.0 0.7 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain Vta1 PF04652.16 CP017026_00063 - 2.5 8.1 10.2 0.043 13.8 1.0 2.5 3 0 0 3 3 3 0 Vta1 like DUF2974 PF11187.8 CP017026_00064 - 1.4e-06 28.0 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CP017026_00064 - 1e-05 25.4 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CP017026_00064 - 0.0019 17.7 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CP017026_00064 - 0.0036 17.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF4450 PF14614.6 CP017026_00064 - 0.016 14.8 0.2 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4450) UPF0227 PF05728.12 CP017026_00064 - 0.028 14.4 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 CP017026_00064 - 0.028 13.0 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CP017026_00064 - 0.049 14.2 0.0 0.069 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CP017026_00065 - 0.00072 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 CP017026_00065 - 0.044 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CP017026_00065 - 0.1 12.4 0.2 0.28 11.1 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Put_DNA-bind_N PF06971.13 CP017026_00069 - 0.034 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus AAA_31 PF13614.6 CP017026_00071 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017026_00071 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017026_00071 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 CP017026_00072 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_25 PF13481.6 CP017026_00073 - 4.8e-15 55.7 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP017026_00073 - 0.0003 20.2 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP017026_00073 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP017026_00073 - 0.0091 15.4 0.4 0.074 12.4 0.0 2.5 3 1 0 3 3 3 1 KaiC AAA PF00004.29 CP017026_00073 - 0.021 15.2 0.5 0.33 11.4 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ApoC-I PF04691.12 CP017026_00073 - 0.16 11.9 3.3 5.1 7.1 0.0 3.9 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) CbiA PF01656.23 CP017026_00073 - 0.24 11.4 2.2 1.1 9.4 2.2 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 CP017026_00073 - 0.7 9.5 5.5 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain DUF1947 PF09183.10 CP017026_00073 - 0.73 10.2 6.3 1.7 9.0 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) HicA_toxin PF07927.12 CP017026_00074 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP017026_00075 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CP017026_00077 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 CP017026_00077 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 CP017026_00077 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) nec1 PF10379.9 CP017026_00078 - 0.036 13.6 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 CP017026_00080 - 3.2e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 CP017026_00080 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP017026_00080 - 0.12 13.0 3.6 1.2 9.8 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Paz_1 PF18349.1 CP017026_00080 - 0.12 12.3 0.9 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 PAZ domain TSC21 PF15217.6 CP017026_00080 - 0.17 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 TSC21 family CdvA PF18822.1 CP017026_00082 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 CP017026_00082 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 CP017026_00082 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 CP017026_00083 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP017026_00083 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP017026_00083 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP017026_00083 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP017026_00083 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 CP017026_00084 - 3.7e-10 39.8 7.6 3.7e-10 39.8 7.6 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain Peptidase_C39 PF03412.15 CP017026_00086 - 4.3e-18 65.4 0.0 5.6e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 CP017026_00086 - 9.8e-05 22.4 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 CP017026_00086 - 0.046 14.3 0.0 0.099 13.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family GramPos_pilinBB PF16569.5 CP017026_00089 - 0.016 16.0 3.9 0.19 12.6 1.9 2.3 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain DUF2768 PF10966.8 CP017026_00089 - 0.052 14.0 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SNF2_N PF00176.23 CP017026_00090 - 2.6e-16 59.3 1.7 4.4e-16 58.5 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP017026_00090 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP017026_00090 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP017026_00090 - 7.6e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP017026_00090 - 2.2e-05 24.9 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP017026_00091 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 CP017026_00092 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017026_00092 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017026_00092 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP017026_00092 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP017026_00092 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP017026_00093 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP017026_00093 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP017026_00094 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP017026_00094 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP017026_00094 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP017026_00094 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP017026_00094 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP017026_00095 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP017026_00095 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP017026_00095 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP017026_00095 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP017026_00095 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP017026_00095 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP017026_00095 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 CP017026_00096 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 CP017026_00097 - 0.047 13.8 0.3 4.4 7.5 0.0 2.3 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 CP017026_00098 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP017026_00098 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain GTP_EFTU PF00009.27 CP017026_00101 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP017026_00101 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP017026_00101 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP017026_00101 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP017026_00101 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP017026_00101 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP017026_00101 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP017026_00101 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP017026_00101 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 CP017026_00103 - 1.2e-05 25.3 2.3 3.2e-05 23.8 2.3 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP017026_00103 - 0.03 14.3 4.7 0.03 14.3 1.1 2.5 1 1 0 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 CP017026_00105 - 9e-97 324.7 8.0 1.3e-96 324.2 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP017026_00105 - 9.7e-12 45.0 0.1 9.7e-12 45.0 0.1 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP017026_00105 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP017026_00105 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP017026_00105 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP017026_00105 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP017026_00105 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 CP017026_00105 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 CP017026_00105 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP017026_00105 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 CP017026_00105 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP017026_00105 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP017026_00105 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP017026_00105 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP017026_00105 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP017026_00105 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP017026_00105 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1461 PF07314.11 CP017026_00106 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CdhD PF03599.16 CP017026_00107 - 0.004 15.9 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 CP017026_00107 - 0.056 13.2 0.7 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP017026_00108 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 CP017026_00108 - 1.3 8.8 9.6 3.3 7.4 8.5 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT20 PF14931.6 CP017026_00108 - 4.9 7.3 10.2 1.5 9.0 0.5 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 TrbM PF07424.11 CP017026_00109 - 3.9e-38 130.8 2.1 5e-38 130.5 2.1 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 CP017026_00109 - 0.17 10.9 0.1 1 8.4 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Cag12 PF13117.6 CP017026_00110 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP017026_00110 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) T4SS-DNA_transf PF02534.14 CP017026_00111 - 6.8e-104 348.3 0.1 9.2e-104 347.8 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP017026_00111 - 3.1e-24 85.3 0.0 6.1e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP017026_00111 - 2.6e-15 56.3 0.0 5.1e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 CP017026_00112 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP017026_00112 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP017026_00112 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP017026_00112 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP017026_00112 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP017026_00112 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CP017026_00112 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CP017026_00112 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP017026_00112 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP017026_00112 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP017026_00112 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP017026_00112 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 CP017026_00112 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 CP017026_00112 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CP017026_00112 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 CP017026_00112 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 CP017026_00112 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 CP017026_00112 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CP017026_00112 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 CP017026_00112 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CP017026_00112 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 CP017026_00112 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP017026_00112 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP017026_00112 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP017026_00112 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP017026_00112 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP017026_00112 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP017026_00112 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP017026_00112 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP017026_00112 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP017026_00112 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CP017026_00113 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP017026_00113 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CP017026_00114 - 4.5e-56 189.9 2.1 7.1e-56 189.3 2.1 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 CP017026_00114 - 0.021 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 TraE protein VirB8 PF04335.13 CP017026_00115 - 1.6e-52 178.4 0.4 1.8e-52 178.3 0.4 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP017026_00115 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 CP017026_00116 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 CP017026_00116 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 CP017026_00116 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 CP017026_00117 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP017026_00117 - 0.065 13.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 CP017026_00117 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) T4SS PF07996.11 CP017026_00118 - 1.8e-28 100.3 13.3 2.5e-28 99.9 13.3 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP017026_00118 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 CP017026_00118 - 0.017 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 CP017026_00118 - 0.5 11.1 11.4 0.41 11.3 4.5 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 CP017026_00119 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP017026_00119 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP017026_00119 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP017026_00119 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CP017026_00120 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 CP017026_00121 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 CP017026_00122 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 CP017026_00122 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 CP017026_00122 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 CP017026_00123 - 6.9e-51 173.3 0.4 1.6e-50 172.1 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP017026_00123 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 CP017026_00124 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP017026_00124 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP017026_00126 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 CRISPR associated protein Cas2 Resolvase PF00239.21 CP017026_00127 - 1.4e-33 116.0 0.8 2e-33 115.6 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_Mga PF08280.11 CP017026_00127 - 0.03 14.4 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_38 PF13936.6 CP017026_00127 - 0.042 13.6 0.8 4.9 7.0 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain RepL PF05732.11 CP017026_00128 - 5.2e-17 61.8 0.0 6e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_5 PF01022.20 CP017026_00128 - 6.3e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 CP017026_00128 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF4423 PF14394.6 CP017026_00128 - 0.00096 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_11 PF08279.12 CP017026_00128 - 0.0036 17.2 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 CP017026_00128 - 0.0037 17.2 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 CP017026_00128 - 0.0046 16.8 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 CP017026_00128 - 0.0048 16.9 0.0 0.0068 16.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 CP017026_00128 - 0.023 15.0 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 CP017026_00128 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_rep_org_N PF09681.10 CP017026_00128 - 0.038 13.9 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) CRISPR_Cas2 PF09827.9 CP017026_00129 - 1.6e-11 44.2 0.1 2e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas2 Citrate_ly_lig PF08218.11 CP017026_00129 - 0.093 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain TIR_2 PF13676.6 CP017026_00130 - 2.1e-05 25.1 0.1 8.4e-05 23.2 0.1 2.1 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 CP017026_00130 - 0.012 16.0 1.2 0.012 16.0 1.2 3.1 3 1 0 3 3 3 0 MTH538 TIR-like domain (DUF1863) T_Ag_DNA_bind PF02217.16 CP017026_00130 - 2.7 8.6 7.4 0.19 12.3 1.8 2.0 2 1 0 2 2 2 0 Origin of replication binding protein DUF1899 PF08953.11 CP017026_00131 - 0.095 12.6 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) XhlA PF10779.9 CP017026_00131 - 0.12 12.6 1.7 0.25 11.6 1.7 1.6 1 0 0 1 1 1 0 Haemolysin XhlA AAA_25 PF13481.6 CP017026_00132 - 5.2e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP017026_00132 - 0.00056 19.3 0.0 0.0044 16.4 0.0 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP017026_00132 - 0.0015 18.3 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP017026_00132 - 0.0044 16.8 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP017026_00132 - 0.0061 15.9 0.1 0.046 13.1 0.0 2.6 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP017026_00132 - 0.092 13.2 0.2 1.4 9.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP017026_00132 - 0.2 11.7 1.5 0.69 10.0 1.4 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicA_toxin PF07927.12 CP017026_00133 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP017026_00134 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system TRADD_N PF09034.10 CP017026_00135 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain Peptidase_M4_C PF02868.15 CP017026_00135 - 0.18 11.7 1.3 0.37 10.6 0.1 2.0 2 1 1 3 3 3 0 Thermolysin metallopeptidase, alpha-helical domain AAA_31 PF13614.6 CP017026_00136 - 6.3e-05 23.0 0.6 0.0013 18.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017026_00136 - 0.0021 18.1 0.8 0.017 15.2 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017026_00136 - 0.02 14.4 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 CP017026_00137 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG NYN PF01936.18 CP017026_00139 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 CP017026_00139 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 CP017026_00139 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain DUF2400 PF09674.10 CP017026_00140 - 0.26 11.2 4.0 0.56 10.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 CP017026_00141 - 3.2e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 CP017026_00141 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP017026_00141 - 0.12 13.0 3.6 1.2 9.8 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Paz_1 PF18349.1 CP017026_00141 - 0.12 12.3 0.9 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 PAZ domain TSC21 PF15217.6 CP017026_00141 - 0.17 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 TSC21 family CitMHS PF03600.16 CP017026_00147 - 0.014 14.6 0.6 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 CP017026_00147 - 0.27 10.9 6.3 0.4 10.4 6.3 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 CP017026_00147 - 0.46 9.9 7.7 0.75 9.2 7.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DUF3810 PF12725.7 CP017026_00147 - 0.68 9.2 12.4 0.82 8.9 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DHHC PF01529.20 CP017026_00147 - 8.2 6.5 12.2 15 5.7 12.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase CitMHS PF03600.16 CP017026_00149 - 0.014 14.6 0.6 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 CP017026_00149 - 0.27 10.9 6.3 0.4 10.4 6.3 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 CP017026_00149 - 0.46 9.9 7.7 0.75 9.2 7.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DUF3810 PF12725.7 CP017026_00149 - 0.68 9.2 12.4 0.82 8.9 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DHHC PF01529.20 CP017026_00149 - 8.2 6.5 12.2 15 5.7 12.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3344 PF11824.8 CP017026_00151 - 0.087 12.4 0.5 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) DUF5013 PF16405.5 CP017026_00153 - 0.0095 16.2 0.0 0.08 13.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5013) AMPK1_CBM PF16561.5 CP017026_00153 - 0.088 13.0 0.0 0.41 10.9 0.0 2.1 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Ribophorin_II PF05817.14 CP017026_00154 - 1.4 7.4 7.7 2 6.9 7.7 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II SseC PF04888.12 CP017026_00157 - 0.004 16.8 0.2 0.014 15.1 0.2 1.9 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 CP017026_00157 - 0.014 14.8 0.8 0.036 13.4 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 CP017026_00157 - 0.036 14.0 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 CP017026_00157 - 0.062 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Ank_3 PF13606.6 CP017026_00159 - 3.6e-09 36.1 0.2 0.013 16.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 CP017026_00159 - 4.6e-08 33.5 0.0 3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CP017026_00159 - 0.00033 21.0 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CP017026_00159 - 0.0019 18.5 0.3 0.03 14.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CP017026_00159 - 0.0027 18.3 0.1 0.17 12.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 CP017026_00160 - 1.6e-07 31.5 0.0 1.6e-07 31.5 0.0 3.3 2 1 0 2 2 2 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 CP017026_00160 - 8.1 6.2 10.9 1.6 8.5 0.6 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF4637 PF15470.6 CP017026_00160 - 9.9 5.9 8.5 0.49 10.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Ank_3 PF13606.6 CP017026_00161 - 3.6e-09 36.1 0.2 0.013 16.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 CP017026_00161 - 4.6e-08 33.5 0.0 3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CP017026_00161 - 0.00033 21.0 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CP017026_00161 - 0.0019 18.5 0.3 0.03 14.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CP017026_00161 - 0.0027 18.3 0.1 0.17 12.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ntox24 PF15529.6 CP017026_00164 - 0.0021 18.3 0.8 0.0039 17.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial toxin 24 CobN-Mg_chel PF02514.16 CP017026_00165 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase LPD7 PF18821.1 CP017026_00166 - 0.0092 16.1 0.4 3 8.0 0.1 2.3 1 1 1 2 2 2 2 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 CP017026_00166 - 0.13 12.8 10.6 0.13 12.8 3.6 3.1 1 1 2 3 3 3 0 Immunity protein 59 ABC2_membrane_3 PF12698.7 CP017026_00166 - 0.29 10.2 0.8 0.32 10.1 0.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AHH PF14412.6 CP017026_00167 - 6.2e-16 58.5 1.7 1.2e-15 57.6 1.7 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF4299 PF14132.6 CP017026_00169 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 CP017026_00169 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 CP017026_00169 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region Phage_GPD PF05954.11 CP017026_00171 - 5.5e-18 65.3 0.0 8.6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 CP017026_00171 - 0.11 12.1 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family DivIC PF04977.15 CP017026_00173 - 0.0014 18.3 0.2 0.0014 18.3 0.2 4.2 5 0 0 5 5 5 1 Septum formation initiator DZR PF12773.7 CP017026_00174 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 CP017026_00174 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 CP017026_00174 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rapsyn_N PF10579.9 CP017026_00175 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SprT-like PF10263.9 CP017026_00177 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 CP017026_00177 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain Phage_integrase PF00589.22 CP017026_00180 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CP017026_00180 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 CP017026_00180 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 CP017026_00180 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 CP017026_00180 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 CP017026_00180 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlaC_arch PF05377.11 CP017026_00181 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) WGR PF05406.15 CP017026_00182 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 CP017026_00182 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like YafQ_toxin PF15738.5 CP017026_00186 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 CP017026_00186 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 CP017026_00186 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 CP017026_00186 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system CCDC-167 PF15188.6 CP017026_00191 - 0.002 18.4 0.4 0.0033 17.7 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 CP017026_00191 - 0.015 15.4 3.5 0.04 14.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) HSBP1 PF06825.12 CP017026_00191 - 0.033 14.0 0.1 2.2 8.2 0.0 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Streptin-Immun PF11083.8 CP017026_00191 - 0.052 14.0 0.6 0.2 12.1 0.1 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4164 PF13747.6 CP017026_00191 - 0.1 12.9 0.4 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Trimer_CC PF08954.11 CP017026_00191 - 0.14 11.7 0.1 9.8 5.8 0.0 3.0 1 1 1 2 2 2 0 Trimerisation motif Sigma_reg_N PF13800.6 CP017026_00192 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5601 PF18151.1 CP017026_00193 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 CP017026_00193 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) HTH_3 PF01381.22 CP017026_00195 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 CP017026_00195 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 CP017026_00195 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 CP017026_00195 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP017026_00195 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 CP017026_00195 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 CP017026_00195 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 CP017026_00195 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CP017026_00195 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CP017026_00195 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 CP017026_00195 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CP017026_00195 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 CP017026_00195 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CP017026_00195 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 CP017026_00195 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 CP017026_00195 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 CP017026_00195 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 CP017026_00195 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 CP017026_00195 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 CP017026_00195 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain LysE PF01810.18 CP017230_00001 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP017230_00001 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP017230_00001 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP017230_00001 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP017230_00001 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP017230_00001 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP017230_00001 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP017230_00001 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP017230_00001 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 CP017230_00002 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP017230_00002 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP017230_00002 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP017230_00002 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP017230_00002 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP017230_00003 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP017230_00003 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP017230_00004 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017230_00004 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017230_00004 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP017230_00004 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP017230_00004 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP017230_00005 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP017230_00006 - 3.5e-16 58.9 1.1 7.4e-16 57.8 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP017230_00006 - 4e-08 33.4 8.0 4e-08 33.4 8.0 4.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP017230_00006 - 1.2e-06 28.8 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP017230_00006 - 5.8e-06 26.2 1.2 0.0013 18.5 0.2 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP017230_00006 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 CP017230_00007 - 0.0008 19.8 0.1 0.002 18.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2768 PF10966.8 CP017230_00007 - 0.011 16.1 0.9 0.026 15.0 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) Acetyltransf_1 PF00583.25 CP017230_00007 - 0.021 15.1 0.1 0.051 13.8 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GramPos_pilinBB PF16569.5 CP017230_00007 - 0.22 12.3 4.3 0.17 12.7 1.7 1.9 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain CooC_C PF15976.5 CP017230_00009 - 0.12 12.4 0.4 0.62 10.2 0.2 2.1 2 0 0 2 2 2 0 CS1-pili formation C-terminal EVI2A PF05399.11 CP017230_00009 - 2.8 7.5 10.5 6.1 6.4 10.5 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Peptidase_C39 PF03412.15 CP017230_00011 - 9e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 CP017230_00011 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 CP017230_00011 - 0.086 13.4 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family Relaxase PF03432.14 CP017230_00013 - 1.6e-10 41.1 7.7 1.6e-10 41.1 7.7 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP017230_00014 - 4.6e-05 23.3 7.5 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP017230_00014 - 0.032 14.4 2.3 0.041 14.0 1.6 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP017230_00014 - 0.1 12.7 5.3 1.5 8.9 0.3 2.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP017230_00014 - 0.48 10.7 7.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 CP017230_00015 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP017230_00015 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP017230_00015 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 CP017230_00018 - 2.3e-08 34.3 0.2 6.4e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP017230_00018 - 0.024 14.9 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein 5_3_exonuc PF01367.20 CP017230_00018 - 0.36 11.5 2.6 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP017230_00019 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP017230_00019 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain DUF1451 PF07295.11 CP017230_00020 - 0.00056 20.0 0.0 0.00063 19.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain DUF4145 PF13643.6 CP017230_00021 - 2.5e-16 59.6 5.0 1.4e-15 57.1 0.1 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4145) Glyco_hydro_16 PF00722.21 CP017230_00024 - 0.081 12.4 0.4 0.081 12.4 0.4 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 HicB_lk_antitox PF15919.5 CP017230_00025 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP017230_00026 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP017230_00027 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP017230_00027 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP017230_00027 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP017230_00027 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP017230_00027 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP017230_00027 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 CP017230_00028 - 0.012 15.5 0.4 0.02 14.7 0.4 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 CP017230_00030 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP017230_00030 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP017230_00030 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP017230_00030 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP017230_00031 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP017230_00031 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP017230_00033 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP017230_00033 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP017230_00034 - 7.4e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP017230_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP017230_00034 - 3.9e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP017230_00034 - 0.033 14.3 5.2 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 CP017230_00035 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP017230_00035 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP017230_00035 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP017230_00035 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP017230_00035 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 CP017230_00036 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 CP017230_00037 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP017230_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP017230_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP017230_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP017230_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP017230_00039 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP017230_00039 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP017230_00039 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP017230_00039 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP017230_00039 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 CP017230_00039 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 CP017230_00039 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 CP017230_00039 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 CP017230_00040 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP017230_00040 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP017230_00040 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP017230_00041 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP017230_00041 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP017230_00042 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP017230_00042 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP017230_00043 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP017230_00043 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP017230_00044 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP017230_00044 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP017230_00045 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP017230_00045 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP017230_00045 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP017230_00045 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP017230_00045 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP017230_00045 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP017230_00045 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP017230_00045 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP017230_00045 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP017230_00045 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP017230_00045 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP017230_00045 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP017230_00045 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP017230_00045 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP017230_00045 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP017230_00045 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP017230_00045 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP017230_00045 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP017230_00045 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP017230_00045 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP017230_00045 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP017230_00045 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP017230_00045 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP017230_00045 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP017230_00045 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP017230_00045 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP017230_00045 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP017230_00045 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP017230_00045 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP017230_00045 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP017230_00045 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP017230_00046 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP017230_00046 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP017230_00046 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP017230_00046 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP017230_00047 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP017230_00047 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP017230_00047 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP017230_00047 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP017230_00048 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP017230_00049 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP017230_00049 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP017230_00049 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP017230_00051 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP017230_00052 - 1.4e-97 327.4 8.2 1.9e-97 326.9 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP017230_00052 - 4.7e-12 46.0 3.1 5.4e-12 45.8 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP017230_00052 - 0.05 13.4 2.1 0.14 12.0 2.1 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP017230_00052 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon EF-hand_8 PF13833.6 CP017230_00052 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP017230_00052 - 0.34 11.1 3.3 0.78 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 CP017230_00053 - 4.7e-05 23.3 2.2 0.00012 22.0 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP017230_00053 - 0.025 14.5 4.1 0.18 11.7 4.1 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 CP017230_00055 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP017230_00055 - 3.4e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP017230_00055 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP017230_00055 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP017230_00055 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP017230_00055 - 0.0015 18.9 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP017230_00055 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP017230_00055 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP017230_00055 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 CP017230_00055 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Rrp15p PF07890.12 CP017230_00057 - 0.41 11.0 7.3 0.42 10.9 7.3 1.1 1 0 0 1 1 1 0 Rrp15p Oxysterol_BP PF01237.18 CP017230_00057 - 0.82 8.4 6.8 0.84 8.4 6.8 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Asp4 PF16996.5 CP017230_00057 - 1.1 9.1 4.3 0.9 9.4 2.6 1.7 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 Casc1_N PF15927.5 CP017230_00057 - 1.8 8.2 14.1 2.1 8.0 14.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Herpes_UL56 PF04534.12 CP017230_00057 - 2.6 7.5 9.7 3.2 7.2 9.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Radial_spoke_3 PF06098.11 CP017230_00057 - 5.5 6.2 13.0 6 6.1 13.0 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 CtsR_C PF17727.1 CP017230_00060 - 0.019 15.1 0.2 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain AAA_31 PF13614.6 CP017417_00001 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017417_00001 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017417_00001 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RseC_MucC PF04246.12 CP017417_00002 - 9.1 6.3 6.3 2.4 8.1 3.1 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NnrS PF05940.12 CP017417_00003 - 0.023 14.1 9.9 0.028 13.8 9.9 1.0 1 0 0 1 1 1 0 NnrS protein DUF2070 PF09843.9 CP017417_00003 - 0.054 11.8 13.4 0.063 11.6 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 CP017417_00003 - 0.15 12.4 19.9 0.53 10.7 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 CP017417_00003 - 0.51 9.7 27.0 0.49 9.7 7.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF5385 PF17359.2 CP017417_00003 - 0.52 9.8 9.3 0.099 12.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NVEALA PF14055.6 CP017417_00003 - 4.1 7.4 6.4 4.2 7.4 0.2 2.9 1 1 2 3 3 3 0 NVEALA protein TssN PF17555.2 CP017417_00003 - 4.7 6.5 20.7 5.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2663 PF10864.8 CP017417_00003 - 6.7 7.1 10.9 36 4.8 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Lipase_3 PF01764.25 CP017417_00004 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CP017417_00004 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 CP017417_00004 - 2.7e-05 24.0 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CP017417_00004 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 CP017417_00004 - 0.00045 19.9 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CP017417_00004 - 0.0017 19.0 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CP017417_00004 - 0.0021 18.1 0.9 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 CP017417_00004 - 0.016 14.8 0.1 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF1257 PF06868.11 CP017417_00004 - 0.24 11.7 2.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) SBDS PF01172.18 CP017417_00004 - 0.79 9.8 5.3 0.83 9.8 1.4 3.2 2 2 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein SseC PF04888.12 CP017417_00007 - 0.0012 18.5 0.2 0.0032 17.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family APOBEC_C PF05240.14 CP017417_00007 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ThrE PF06738.12 CP017417_00007 - 0.019 14.3 0.8 0.051 12.9 0.8 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 CP017417_00007 - 0.033 14.1 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone PTS_EIIC_2 PF13303.6 CP017417_00007 - 0.037 13.1 1.0 0.064 12.3 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC TPR_11 PF13414.6 CP017417_00007 - 0.064 12.9 0.3 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 TPR repeat Glyco_tranf_2_5 PF13712.6 CP017417_00009 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 CP017417_00010 - 3.3e-42 144.9 22.9 3.3e-42 144.9 22.9 2.2 2 1 0 2 2 2 1 TraG-like protein, N-terminal region CHMI PF02962.15 CP017417_00010 - 0.017 15.5 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 CP017417_00013 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 CP017417_00013 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 CP017417_00013 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 CP017417_00013 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 CP017417_00015 - 8.6e-09 35.6 0.3 0.00036 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 CP017417_00015 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 CP017417_00016 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 CP017417_00018 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 CP017417_00018 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein DHHA1 PF02272.19 CP017417_00019 - 0.18 12.2 1.6 0.37 11.2 1.6 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 CP017417_00020 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 CP017417_00021 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 CP017417_00021 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 CP017417_00021 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 CP017417_00023 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 CP017417_00023 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 CP017417_00025 - 1.5e-25 89.9 0.2 4e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family CooC_C PF15976.5 CP017417_00027 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 CP017417_00027 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 CP017417_00028 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 CP017417_00028 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 CP017417_00028 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 CP017417_00028 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 CP017417_00028 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CP017417_00028 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 CP017417_00028 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 CP017417_00028 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CP017417_00028 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CP017417_00028 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 CP017417_00028 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CP017417_00028 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 CP017417_00028 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 CP017417_00028 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 CP017417_00028 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 CP017417_00028 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 CP017417_00028 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 CP017417_00028 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 CP017417_00028 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 CP017417_00028 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 CP017417_00030 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 CP017417_00030 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HSBP1 PF06825.12 CP017417_00033 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 CP017417_00033 - 0.026 14.9 0.3 0.039 14.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 CP017417_00033 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 CP017417_00033 - 0.11 12.8 0.3 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_NinH PF06322.11 CP017417_00034 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein WGR PF05406.15 CP017417_00038 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 CP017417_00038 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 CP017417_00039 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 CP017417_00040 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CP017417_00040 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 CP017417_00040 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 CP017417_00040 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 CP017417_00040 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 CP017417_00040 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 CP017417_00040 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Prok-TraM PF09228.10 CP017417_00042 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 CP017417_00042 - 3 8.1 11.1 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 CP017417_00043 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 CP017417_00044 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 CP017417_00044 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 CP017417_00044 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 CP017417_00046 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 CP017417_00046 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 CP017417_00048 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 CP017417_00050 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 CP017417_00050 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 CP017417_00050 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 CP017417_00052 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 CP017417_00053 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 CP017417_00053 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 CP017417_00053 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 CP017417_00053 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myc-LZ PF02344.15 CP017417_00054 - 0.045 13.9 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Myc leucine zipper domain Importin_rep PF18773.1 CP017417_00055 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 CP017417_00055 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 CP017417_00055 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 CP017417_00056 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 CP017417_00056 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 CP017417_00057 - 3.5e-47 161.1 0.0 3.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 CP017417_00058 - 1.6e-110 370.4 0.0 1.8e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 CP017417_00059 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 CP017417_00059 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 CP017417_00059 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 CP017417_00060 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 CP017417_00060 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 CP017417_00061 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 CP017417_00061 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 CP017417_00062 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 CP017417_00062 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 CP017417_00062 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 CP017417_00062 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 CP017417_00063 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 CP017417_00064 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 CP017417_00065 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 CP017417_00066 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 CP017417_00067 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 CP017417_00067 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 CP017417_00067 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 CP017417_00067 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CP017417_00067 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 CP017417_00067 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 CP017417_00067 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 CP017417_00068 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CP017417_00068 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 CP017417_00068 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3870 PF12986.7 CP017417_00069 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) DUF2459 PF09601.10 CP017417_00072 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) BLOC1_2 PF10046.9 CP017417_00072 - 0.1 12.9 2.0 0.25 11.7 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_DNA-bind_N PF06971.13 CP017417_00073 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Toprim_3 PF13362.6 CP017417_00074 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP017417_00074 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP017417_00074 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 CP017417_00074 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold NYN PF01936.18 CP017417_00076 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 CP017417_00076 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 CP017417_00076 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain AAA_31 PF13614.6 CP017418_00001 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017418_00001 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017418_00001 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 CP017418_00002 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP017418_00003 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP017418_00003 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP017418_00003 - 9.4e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP017418_00003 - 1.3e-05 25.0 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP017418_00003 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase HTH_19 PF12844.7 CP017418_00004 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 CP017418_00004 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 CP017418_00004 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 CP017418_00004 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CP017418_00004 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP017418_00004 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 CP017418_00004 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 CP017418_00004 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 CP017418_00004 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 CP017418_00004 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 CP017418_00004 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CP017418_00004 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 CP017418_00004 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 CP017418_00004 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Relaxase PF03432.14 CP017418_00005 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP017418_00006 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP017418_00006 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP017418_00006 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP017418_00006 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 CP017418_00006 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain CdvA PF18822.1 CP017418_00007 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 CP017418_00007 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 CP017418_00007 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 CP017418_00009 - 0.00054 20.3 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF4223 PF13978.6 CP017418_00010 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 CP017418_00010 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 CP017418_00011 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 CP017418_00011 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 CP017418_00011 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP017418_00013 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP017418_00014 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP017418_00015 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP017418_00015 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP017418_00015 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP017418_00015 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP017418_00015 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP017418_00015 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP017418_00015 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 CP017418_00016 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP017418_00016 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP017418_00016 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 CP017418_00017 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 CP017418_00019 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP017418_00019 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP017418_00020 - 4e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP017418_00020 - 3.7e-21 75.1 1.1 6.4e-21 74.4 1.1 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP017418_00020 - 4.4e-07 29.2 0.5 1e-06 28.0 0.5 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP017418_00020 - 0.0092 16.1 2.9 1.7 8.7 0.0 3.8 4 1 1 5 5 5 2 Helicase HerA, central domain Phage_pRha PF09669.10 CP017418_00021 - 6.6e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP017418_00021 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 CP017418_00021 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) DUF3251 PF11622.8 CP017418_00022 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP017418_00022 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP017418_00022 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP017418_00022 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP017418_00022 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP017418_00022 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 CP017418_00023 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP017418_00024 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP017418_00024 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP017418_00024 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP017418_00024 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP017418_00025 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP017418_00025 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP017418_00025 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP017418_00025 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP017418_00025 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 CP017418_00025 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 CP017418_00025 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 CP017418_00025 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 CP017418_00026 - 2.7e-31 109.0 32.0 2.7e-31 109.0 32.0 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein DUF3176 PF11374.8 CP017418_00026 - 0.088 13.0 0.5 0.088 13.0 0.5 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF3176) T_cell_tran_alt PF15128.6 CP017418_00026 - 0.18 11.6 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP017418_00026 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP017418_00027 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP017418_00027 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP017418_00028 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP017418_00028 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP017418_00029 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP017418_00029 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP017418_00030 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP017418_00030 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP017418_00031 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP017418_00031 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP017418_00031 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP017418_00031 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP017418_00031 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP017418_00031 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP017418_00031 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP017418_00031 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP017418_00031 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP017418_00031 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP017418_00031 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP017418_00031 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP017418_00031 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP017418_00031 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP017418_00031 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP017418_00031 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP017418_00031 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP017418_00031 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP017418_00031 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP017418_00031 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP017418_00031 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP017418_00031 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP017418_00031 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP017418_00031 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP017418_00031 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP017418_00031 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP017418_00031 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP017418_00031 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP017418_00031 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP017418_00031 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP017418_00031 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP017418_00032 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP017418_00032 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP017418_00032 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP017418_00032 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP017418_00033 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP017418_00033 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP017418_00033 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP017418_00033 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP017418_00034 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP017418_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP017418_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP017418_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP017418_00037 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP017418_00038 - 1e-96 324.5 8.2 1.4e-96 324.0 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP017418_00038 - 1.5e-12 47.6 0.4 9.4e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP017418_00038 - 1.5e-06 27.9 5.0 3.8e-06 26.6 5.0 1.8 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 CP017418_00038 - 0.079 12.8 0.0 0.28 11.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair zinc_ribbon_9 PF14369.6 CP017418_00038 - 0.22 11.8 0.7 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 zinc-ribbon HTH_34 PF13601.6 CP017418_00038 - 0.4 10.9 3.3 0.79 9.9 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 CP017418_00039 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP017418_00039 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain GTP_EFTU PF00009.27 CP017418_00041 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP017418_00041 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP017418_00041 - 9.3e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP017418_00041 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP017418_00041 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP017418_00041 - 0.00031 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP017418_00041 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP017418_00041 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP017418_00041 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF5442 PF17514.2 CP017418_00042 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 CP017418_00044 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP017418_00044 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 CP017418_00045 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP017418_00045 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 CP017418_00046 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 CP017418_00047 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP017418_00047 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP017418_00047 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP017418_00047 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP017418_00047 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP017418_00047 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP017418_00047 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 CP017418_00048 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP017418_00048 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP017418_00048 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP017418_00048 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP017418_00048 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP017418_00049 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP017418_00049 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Toprim_3 PF13362.6 CP017854_00001 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP017854_00001 - 0.016 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP017854_00001 - 0.017 15.2 6.4 1.2 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 DUF4223 PF13978.6 CP017854_00002 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP017854_00002 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 CP017854_00003 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 CP017854_00004 - 5.1e-29 101.4 6.3 9.5e-29 100.6 6.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CP017854_00004 - 2e-26 92.8 0.9 3.2e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CP017854_00004 - 4e-06 25.9 0.8 5.9e-06 25.3 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 CP017854_00004 - 0.0032 17.5 0.9 0.0087 16.1 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) RIO1 PF01163.22 CP017854_00004 - 0.0073 15.9 2.5 0.0073 15.9 2.5 1.6 2 0 0 2 2 2 1 RIO1 family ORC6 PF05460.13 CP017854_00004 - 0.0086 15.4 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pectate_lyase_3 PF12708.7 CP017854_00004 - 0.068 13.0 0.4 0.14 12.0 0.4 1.4 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pex19 PF04614.12 CP017854_00004 - 3.6 7.3 5.4 7.5 6.2 5.4 1.5 1 0 0 1 1 1 0 Pex19 protein family HicB_lk_antitox PF15919.5 CP017854_00006 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP017854_00006 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 CP017854_00007 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP017854_00007 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP017854_00007 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP017854_00007 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP017854_00007 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP017854_00007 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 CP017854_00008 - 0.013 15.3 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 CP017854_00010 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP017854_00010 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP017854_00010 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP017854_00010 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP017854_00011 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP017854_00011 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP017854_00013 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP017854_00013 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP017854_00014 - 1.3e-51 175.6 0.7 3e-51 174.5 0.7 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP017854_00014 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 CP017854_00014 - 0.045 13.2 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 CP017854_00015 - 1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP017854_00015 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 CP017854_00016 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP017854_00016 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP017854_00016 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP017854_00016 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP017854_00016 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP017854_00016 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 CP017854_00017 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP017854_00018 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP017854_00018 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP017854_00018 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP017854_00018 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP017854_00019 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP017854_00019 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP017854_00019 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 CP017854_00019 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 CP017854_00019 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 CP017854_00019 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 CP017854_00020 - 4.7e-29 101.7 31.2 4.7e-29 101.7 31.2 1.8 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP017854_00020 - 0.22 11.3 1.3 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP017854_00020 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP017854_00021 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP017854_00021 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP017854_00022 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP017854_00022 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP017854_00023 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP017854_00023 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP017854_00024 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP017854_00024 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP017854_00025 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP017854_00025 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP017854_00025 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP017854_00025 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP017854_00025 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP017854_00025 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP017854_00025 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP017854_00025 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP017854_00025 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP017854_00025 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP017854_00025 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP017854_00025 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP017854_00025 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP017854_00025 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP017854_00025 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP017854_00025 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP017854_00025 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP017854_00025 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP017854_00025 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP017854_00025 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP017854_00025 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP017854_00025 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP017854_00025 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP017854_00025 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP017854_00025 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP017854_00025 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP017854_00025 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP017854_00025 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP017854_00025 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP017854_00025 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP017854_00025 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP017854_00026 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP017854_00026 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP017854_00026 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP017854_00026 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP017854_00027 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP017854_00027 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP017854_00027 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP017854_00027 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP017854_00028 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP017854_00029 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP017854_00029 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP017854_00029 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP017854_00031 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP017854_00032 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP017854_00032 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 CP017854_00032 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 CP017854_00032 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 CP017854_00032 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP017854_00032 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 CP017854_00033 - 5.1e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP017854_00033 - 0.02 14.8 3.9 0.17 11.9 3.9 2.6 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 CP017854_00035 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP017854_00035 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP017854_00035 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP017854_00035 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP017854_00035 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP017854_00035 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP017854_00035 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP017854_00035 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP017854_00035 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Sgf11 PF08209.11 CP017854_00036 - 0.11 12.1 0.8 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) CtsR_C PF17727.1 CP017854_00037 - 0.031 14.4 0.2 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Lip_prot_lig_C PF10437.9 CP017854_00037 - 0.049 13.6 2.7 0.17 11.9 2.2 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus LysE PF01810.18 CP017854_00038 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP017854_00038 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP017854_00038 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP017854_00038 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP017854_00038 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP017854_00038 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP017854_00038 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP017854_00038 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP017854_00038 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 CP017854_00039 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP017854_00039 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP017854_00039 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP017854_00039 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP017854_00039 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP017854_00040 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP017854_00040 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP017854_00041 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017854_00041 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017854_00041 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP017854_00041 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP017854_00041 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP017854_00042 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP017854_00043 - 2.2e-16 59.5 2.2 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP017854_00043 - 5e-08 33.1 8.3 5e-08 33.1 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP017854_00043 - 9.5e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP017854_00043 - 1.1e-05 25.3 2.2 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP017854_00043 - 3.1e-05 24.4 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase DUF3800 PF12686.7 CP017854_00044 - 6e-06 26.9 8.9 6e-06 26.9 8.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3800) CM_2 PF01817.21 CP017854_00044 - 0.032 14.6 0.2 0.082 13.3 0.2 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Myb_DNA-bind_3 PF12776.7 CP017854_00044 - 2 9.5 5.3 1.6 9.8 0.4 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Relaxase PF03432.14 CP017854_00045 - 3.6e-10 39.9 7.2 3.6e-10 39.9 7.2 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP017854_00046 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP017854_00046 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP017854_00046 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP017854_00046 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP017854_00046 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 CP017854_00047 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP017854_00047 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP017854_00047 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide GTP_EFTU PF00009.27 CP017857_00001 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP017857_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP017857_00001 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP017857_00001 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP017857_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP017857_00001 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP017857_00001 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP017857_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP017857_00001 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Sgf11 PF08209.11 CP017857_00002 - 0.11 12.1 0.8 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) CtsR_C PF17727.1 CP017857_00003 - 0.031 14.4 0.2 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Lip_prot_lig_C PF10437.9 CP017857_00003 - 0.049 13.6 2.7 0.17 11.9 2.2 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus LysE PF01810.18 CP017857_00004 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP017857_00004 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP017857_00004 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP017857_00004 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP017857_00004 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP017857_00004 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP017857_00004 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP017857_00004 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP017857_00004 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 CP017857_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP017857_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP017857_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP017857_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP017857_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP017857_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP017857_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP017857_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP017857_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP017857_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP017857_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP017857_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP017857_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP017857_00009 - 2.2e-16 59.5 2.2 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP017857_00009 - 5e-08 33.1 8.3 5e-08 33.1 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP017857_00009 - 9.5e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP017857_00009 - 1.1e-05 25.3 2.2 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP017857_00009 - 3.1e-05 24.4 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase DUF3800 PF12686.7 CP017857_00010 - 6e-06 26.9 8.9 6e-06 26.9 8.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3800) CM_2 PF01817.21 CP017857_00010 - 0.032 14.6 0.2 0.082 13.3 0.2 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Myb_DNA-bind_3 PF12776.7 CP017857_00010 - 2 9.5 5.3 1.6 9.8 0.4 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Relaxase PF03432.14 CP017857_00011 - 3.6e-10 39.9 7.2 3.6e-10 39.9 7.2 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP017857_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP017857_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP017857_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP017857_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP017857_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 CP017857_00013 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP017857_00013 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP017857_00013 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 CP017857_00016 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP017857_00016 - 0.016 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP017857_00016 - 0.017 15.2 6.4 1.2 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 DUF4223 PF13978.6 CP017857_00017 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP017857_00017 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 CP017857_00018 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 CP017857_00019 - 5.1e-29 101.4 6.3 9.5e-29 100.6 6.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CP017857_00019 - 2e-26 92.8 0.9 3.2e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CP017857_00019 - 4e-06 25.9 0.8 5.9e-06 25.3 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 CP017857_00019 - 0.0032 17.5 0.9 0.0087 16.1 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) RIO1 PF01163.22 CP017857_00019 - 0.0073 15.9 2.5 0.0073 15.9 2.5 1.6 2 0 0 2 2 2 1 RIO1 family ORC6 PF05460.13 CP017857_00019 - 0.0086 15.4 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pectate_lyase_3 PF12708.7 CP017857_00019 - 0.068 13.0 0.4 0.14 12.0 0.4 1.4 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pex19 PF04614.12 CP017857_00019 - 3.6 7.3 5.4 7.5 6.2 5.4 1.5 1 0 0 1 1 1 0 Pex19 protein family HicB_lk_antitox PF15919.5 CP017857_00021 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP017857_00021 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 CP017857_00022 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP017857_00022 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP017857_00022 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP017857_00022 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP017857_00022 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP017857_00022 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 CP017857_00023 - 0.013 15.3 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 CP017857_00025 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP017857_00025 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP017857_00025 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP017857_00025 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP017857_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP017857_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP017857_00028 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP017857_00028 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP017857_00029 - 1.3e-51 175.6 0.7 3e-51 174.5 0.7 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP017857_00029 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 CP017857_00029 - 0.045 13.2 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 CP017857_00030 - 1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP017857_00030 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 CP017857_00031 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP017857_00031 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP017857_00031 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP017857_00031 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP017857_00031 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP017857_00031 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 CP017857_00032 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP017857_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP017857_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP017857_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP017857_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP017857_00034 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP017857_00034 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP017857_00034 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 CP017857_00034 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 CP017857_00034 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 CP017857_00034 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 CP017857_00035 - 4.7e-29 101.7 31.2 4.7e-29 101.7 31.2 1.8 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP017857_00035 - 0.22 11.3 1.3 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP017857_00035 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP017857_00036 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP017857_00036 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP017857_00037 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP017857_00037 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP017857_00038 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP017857_00038 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP017857_00039 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP017857_00039 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP017857_00040 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP017857_00040 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP017857_00040 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP017857_00040 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP017857_00040 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP017857_00040 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP017857_00040 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP017857_00040 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP017857_00040 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP017857_00040 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP017857_00040 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP017857_00040 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP017857_00040 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP017857_00040 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP017857_00040 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP017857_00040 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP017857_00040 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP017857_00040 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP017857_00040 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP017857_00040 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP017857_00040 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP017857_00040 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP017857_00040 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP017857_00040 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP017857_00040 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP017857_00040 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP017857_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP017857_00040 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP017857_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP017857_00040 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP017857_00040 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP017857_00041 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP017857_00041 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP017857_00041 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP017857_00041 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP017857_00042 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP017857_00042 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP017857_00042 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP017857_00042 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP017857_00043 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP017857_00044 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP017857_00044 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP017857_00044 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP017857_00046 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP017857_00047 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP017857_00047 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 CP017857_00047 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 CP017857_00047 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 CP017857_00047 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP017857_00047 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 CP017857_00048 - 5.1e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP017857_00048 - 0.02 14.8 3.9 0.17 11.9 3.9 2.6 1 1 0 1 1 1 0 Intein splicing domain IMS PF00817.20 CP018901_00001 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family DUF4368 PF14287.6 CP018901_00002 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 CP018901_00002 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.3 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 CP018901_00002 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 CP018901_00002 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 CP018901_00002 - 0.12 12.5 0.5 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 TnpV PF14198.6 CP018901_00003 - 3.3e-41 139.8 0.5 3.6e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV AAA_18 PF13238.6 CP018901_00004 - 1.2e-14 55.0 0.0 1.5e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CP018901_00004 - 2.4e-11 44.0 0.0 2.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CP018901_00004 - 2.8e-10 40.3 0.0 5.4e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 CP018901_00004 - 1.5e-07 30.9 0.0 3.1e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 CP018901_00004 - 3.6e-06 27.3 0.2 9.9e-06 25.9 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 CP018901_00004 - 8.3e-06 26.3 0.0 5.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CP018901_00004 - 8.6e-06 26.2 0.0 3.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CP018901_00004 - 1.5e-05 25.3 0.0 5.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CP018901_00004 - 5.9e-05 23.1 0.0 8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CP018901_00004 - 0.00029 21.2 0.0 0.00036 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 CP018901_00004 - 0.00097 18.5 0.3 0.0011 18.2 0.3 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CP018901_00004 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CP018901_00004 - 0.0016 18.0 0.1 0.0034 16.9 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 CP018901_00004 - 0.0021 17.8 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP018901_00004 - 0.0022 17.8 0.3 0.0036 17.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CP018901_00004 - 0.0025 18.3 0.0 0.0029 18.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.13 CP018901_00004 - 0.0047 16.2 0.3 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain APS_kinase PF01583.20 CP018901_00004 - 0.0047 16.8 0.0 0.088 12.7 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase ATPase PF06745.13 CP018901_00004 - 0.0061 15.9 0.7 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 CP018901_00004 - 0.011 14.9 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DnaB_C PF03796.15 CP018901_00004 - 0.015 14.7 0.5 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 CP018901_00004 - 0.015 14.9 0.1 0.033 13.8 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 CP018901_00004 - 0.015 15.2 0.1 0.93 9.4 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CP018901_00004 - 0.016 15.1 0.5 0.031 14.2 0.2 1.6 2 0 0 2 2 1 0 NTPase Viral_helicase1 PF01443.18 CP018901_00004 - 0.016 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 CP018901_00004 - 0.018 14.8 0.1 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CP018901_00004 - 0.018 14.6 0.3 0.066 12.8 0.1 2.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 CP018901_00004 - 0.024 14.8 0.2 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.15 CP018901_00004 - 0.03 14.3 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Hydin_ADK PF17213.3 CP018901_00004 - 0.032 14.5 0.7 0.05 13.9 0.2 1.5 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain NB-ARC PF00931.22 CP018901_00004 - 0.037 13.2 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MKT1_N PF12247.8 CP018901_00004 - 0.04 14.3 0.0 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication ArsA_ATPase PF02374.15 CP018901_00004 - 0.042 13.0 0.1 0.089 12.0 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase NACHT PF05729.12 CP018901_00004 - 0.045 13.7 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 CP018901_00004 - 0.046 13.5 1.0 0.067 13.0 0.9 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CP018901_00004 - 0.047 14.1 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 CP018901_00004 - 0.053 13.2 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GvpD PF07088.11 CP018901_00004 - 0.054 12.1 0.3 0.38 9.3 0.0 2.1 2 1 1 3 3 3 0 GvpD gas vesicle protein AAA_7 PF12775.7 CP018901_00004 - 0.056 13.0 0.2 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CP018901_00004 - 0.073 12.8 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 CP018901_00004 - 0.076 12.5 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase1 PF18748.1 CP018901_00004 - 0.086 12.4 0.0 2 7.9 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 ATP-synt_ab PF00006.25 CP018901_00004 - 0.086 12.5 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IPT PF01745.16 CP018901_00004 - 0.098 12.0 0.2 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 Isopentenyl transferase Ploopntkinase3 PF18751.1 CP018901_00004 - 0.11 12.4 0.4 0.37 10.7 0.0 2.0 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 CP018901_00004 - 0.18 11.5 0.7 10 5.7 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase APH PF01636.23 CP018901_00005 - 8.6e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP018901_00005 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CP018901_00005 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 CP018901_00005 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 CP018901_00005 - 0.09 12.4 0.4 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 CP018901_00005 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 CP018901_00006 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 CP018901_00007 - 6.8e-11 42.6 0.0 8.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP018901_00007 - 0.014 14.6 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase CPT PF07931.12 CP018901_00008 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CP018901_00008 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CP018901_00008 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 CP018901_00008 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 CP018901_00008 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3847 PF12958.7 CP018901_00009 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 CP018901_00009 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 CP018901_00009 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 CP018901_00009 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MobA_MobL PF03389.15 CP018901_00010 - 3.5e-50 170.8 0.0 3.9e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 MobA/MobL family AAA_25 PF13481.6 CP018901_00011 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 CP018901_00011 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 CP018901_00011 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 CP018901_00011 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 CP018901_00011 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 CP018901_00011 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 CP018901_00011 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CP018901_00011 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 CP018901_00011 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 CP018901_00011 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 CP018901_00011 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 CP018901_00011 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 CP018901_00011 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CP018901_00011 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 CP018901_00011 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 CP018901_00011 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 CP018901_00011 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IMS_C PF11799.8 CP018901_00012 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CP018901_00012 - 0.00028 21.0 0.1 0.00067 19.8 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF447 PF04289.12 CP018901_00014 - 0.029 14.2 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 CP018901_00014 - 0.032 14.1 0.3 0.049 13.6 0.2 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 CP018901_00014 - 0.04 14.0 0.1 0.054 13.6 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3825 PF12873.7 CP018901_00015 - 4.2e-29 101.7 0.3 6.7e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) SGT1 PF07093.11 CP018901_00017 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 CP018901_00017 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 CP018901_00017 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5309 PF17236.2 CP018901_00018 - 3.1e-05 23.5 0.5 3.3e-05 23.4 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5309) HicA_toxin PF07927.12 CP018901_00019 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP018901_00020 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 CP018901_00020 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ParE_toxin PF05016.15 CP018901_00022 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 CP018901_00024 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF4131 PF13567.6 CP018901_00025 - 0.0008 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 CP018901_00025 - 0.015 15.2 3.3 0.019 14.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 CP018901_00025 - 0.056 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2663 PF10864.8 CP018901_00025 - 0.13 12.7 2.1 0.16 12.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2721 PF11026.8 CP018901_00025 - 0.27 11.1 5.3 0.34 10.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TraG_N PF07916.11 CP018901_00026 - 8.5e-39 133.7 20.1 8.5e-39 133.7 20.1 3.3 3 1 0 4 4 4 1 TraG-like protein, N-terminal region Glyco_tranf_2_5 PF13712.6 CP018901_00027 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family UvrA_DNA-bind PF17755.1 CP018901_00028 - 0.00087 19.6 0.5 0.32 11.4 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain SseC PF04888.12 CP018901_00030 - 0.0051 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 CP018901_00030 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter APOBEC_C PF05240.14 CP018901_00030 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Hormone_2 PF00123.20 CP018901_00030 - 0.035 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone Phage_lysozyme PF00959.19 CP018901_00032 - 1.2e-10 41.8 1.2 1.9e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Phage lysozyme Vta1 PF04652.16 CP018901_00032 - 2.2 8.3 10.2 0.054 13.5 1.0 2.9 3 1 1 4 4 4 0 Vta1 like DUF2974 PF11187.8 CP018901_00033 - 1.4e-06 28.0 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CP018901_00033 - 1e-05 25.4 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CP018901_00033 - 0.0019 17.7 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CP018901_00033 - 0.0036 17.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF4450 PF14614.6 CP018901_00033 - 0.016 14.8 0.2 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4450) UPF0227 PF05728.12 CP018901_00033 - 0.028 14.4 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 CP018901_00033 - 0.028 13.0 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CP018901_00033 - 0.049 14.2 0.0 0.069 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CP018901_00034 - 0.0024 17.4 0.1 0.007 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 CP018901_00034 - 0.05 13.1 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CP018901_00034 - 0.11 12.3 0.1 0.44 10.4 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 3) DUF3810 PF12725.7 CP018901_00035 - 0.0026 17.2 5.2 0.0029 17.0 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) CitMHS PF03600.16 CP018901_00035 - 0.023 13.9 0.3 0.023 13.9 0.3 1.0 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 CP018901_00035 - 0.11 12.2 5.7 0.16 11.7 5.7 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 CP018901_00035 - 1.8 7.9 10.7 4.1 6.8 10.3 1.8 1 1 0 1 1 1 0 Spo7-like protein Lipase_3 PF01764.25 CP018901_00038 - 1.5e-08 34.6 0.0 5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CP018901_00038 - 3.1e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 CP018901_00038 - 1.1e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CP018901_00038 - 5.6e-05 23.0 0.1 9.7e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 CP018901_00038 - 0.00041 20.0 0.1 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CP018901_00038 - 0.00064 20.4 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CP018901_00038 - 0.0014 18.6 0.3 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 CP018901_00038 - 0.014 15.3 1.8 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase NMT PF01233.19 CP018901_00038 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Hydrolase_4 PF12146.8 CP018901_00038 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CP018901_00038 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Put_DNA-bind_N PF06971.13 CP018901_00042 - 0.039 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus ATG27 PF09451.10 CP018901_00042 - 0.071 13.0 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Toprim_3 PF13362.6 CP018901_00044 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP018901_00044 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 CP018901_00044 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 CP018901_00044 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Abi_2 PF07751.11 CP018901_00045 - 0.0013 19.1 11.1 0.002 18.4 11.1 1.3 1 0 0 1 1 1 1 Abi-like protein NYN PF01936.18 CP018901_00046 - 1.7e-10 41.6 0.0 1.9e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 CP018901_00046 - 0.0082 16.0 0.7 0.016 15.1 0.7 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 CP018901_00046 - 0.02 15.5 0.0 0.035 14.8 0.0 1.4 1 0 0 1 1 1 0 PIN domain RHH_7 PF16777.5 CP018901_00047 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 CP018901_00047 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 CP018901_00048 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP018901_00048 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP018901_00048 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 CP018901_00048 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF4223 PF13978.6 CP018901_00049 - 0.21 11.6 1.5 0.36 10.8 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) ZapB PF06005.12 CP018901_00050 - 0.094 13.2 0.1 0.095 13.2 0.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF1451 PF07295.11 CP018901_00051 - 0.00056 20.0 0.0 0.00063 19.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain DUF4145 PF13643.6 CP018901_00052 - 8.2e-17 61.1 3.4 1.4e-15 57.1 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4145) HicB_lk_antitox PF15919.5 CP018901_00054 - 1.8e-08 34.5 0.0 2e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP018901_00054 - 0.075 12.4 0.0 0.082 12.3 0.0 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain HicA_toxin PF07927.12 CP018901_00055 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP018901_00056 - 1.7e-15 57.2 0.0 3.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP018901_00056 - 0.00066 19.1 0.0 0.0072 15.7 0.0 2.2 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP018901_00056 - 0.0016 18.2 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP018901_00056 - 0.0031 17.3 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CP018901_00056 - 0.0057 16.0 0.1 0.044 13.1 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP018901_00056 - 0.07 13.6 0.7 0.9 10.0 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP018901_00056 - 0.16 12.0 1.2 0.59 10.2 1.2 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1947 PF09183.10 CP018901_00056 - 0.7 10.2 6.3 1.7 9.0 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) RHH_7 PF16777.5 CP018901_00057 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 CP018901_00057 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 CP018901_00058 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP018901_00058 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP018901_00058 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 CP018901_00058 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF4995 PF16386.5 CP018901_00059 - 0.14 12.2 0.7 0.15 12.1 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF4223 PF13978.6 CP018901_00059 - 0.2 11.6 1.9 0.28 11.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) CitMHS PF03600.16 CP018901_00064 - 0.0018 17.5 0.1 0.0018 17.5 0.1 1.0 1 0 0 1 1 1 1 Citrate transporter DUF3810 PF12725.7 CP018901_00064 - 0.0049 16.3 5.3 0.0058 16.0 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Yip1 PF04893.17 CP018901_00064 - 0.24 11.1 5.6 0.37 10.5 5.6 1.2 1 0 0 1 1 1 0 Yip1 domain Ion_trans PF00520.31 CP018901_00064 - 1.4 8.1 14.4 1.7 7.8 14.4 1.5 1 1 0 1 1 1 0 Ion transport protein DHHC PF01529.20 CP018901_00064 - 1.8 8.6 10.9 3.1 7.9 10.9 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Spo7 PF03907.13 CP018901_00064 - 2.8 7.4 6.8 5.6 6.4 6.8 1.5 1 0 0 1 1 1 0 Spo7-like protein CitMHS PF03600.16 CP018901_00066 - 0.0033 16.7 0.5 0.0039 16.4 0.5 1.1 1 0 0 1 1 1 1 Citrate transporter Yip1 PF04893.17 CP018901_00066 - 0.4 10.4 6.1 0.57 9.9 6.1 1.1 1 0 0 1 1 1 0 Yip1 domain DUF3810 PF12725.7 CP018901_00066 - 0.43 9.9 11.7 0.55 9.5 11.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Ion_trans PF00520.31 CP018901_00066 - 0.5 9.5 12.3 0.78 8.9 12.2 1.4 1 1 0 1 1 1 0 Ion transport protein Spo7 PF03907.13 CP018901_00066 - 2.2 7.7 7.5 3.7 7.0 7.5 1.5 1 1 0 1 1 1 0 Spo7-like protein DHHC PF01529.20 CP018901_00066 - 3.4 7.8 11.8 6.4 6.9 11.8 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Phage_lysozyme PF00959.19 CP018901_00067 - 2.1e-10 41.0 2.1 6e-10 39.6 0.1 2.9 2 0 0 2 2 2 1 Phage lysozyme Lipase_3 PF01764.25 CP018901_00067 - 2.8e-07 30.5 0.0 1e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 CP018901_00067 - 0.00084 19.1 2.0 0.003 17.3 0.0 2.8 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CP018901_00067 - 0.096 13.3 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CP018901_00067 - 0.2 11.8 0.0 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain SseC PF04888.12 CP018901_00069 - 0.014 15.1 0.2 0.014 15.1 0.2 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ThrE PF06738.12 CP018901_00069 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter APOBEC_C PF05240.14 CP018901_00069 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Hormone_2 PF00123.20 CP018901_00069 - 0.035 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone UvrA_DNA-bind PF17755.1 CP018901_00070 - 0.0051 17.1 0.3 3.2 8.1 0.0 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 CP018901_00071 - 0.013 15.8 0.2 6.8 7.1 0.1 2.6 2 0 0 2 2 2 0 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 CP018901_00073 - 0.025 14.9 0.6 11 6.4 0.1 2.7 3 0 0 3 3 3 0 UvrA DNA-binding domain DUF3870 PF12986.7 CP018901_00073 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) FHA PF00498.26 CP018901_00074 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CP018901_00074 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 CP018901_00074 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain ImcF-related_N PF14331.6 CP018901_00075 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 CP018901_00075 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 CP018901_00075 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 CP018901_00075 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CP018901_00075 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 CP018901_00075 - 0.0033 17.1 5.0 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 CP018901_00075 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain T6SS_HCP PF05638.12 CP018901_00076 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp DotU PF09850.9 CP018901_00077 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_VasE PF05936.12 CP018901_00078 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE T6SS-SciN PF12790.7 CP018901_00079 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasJ PF16989.5 CP018901_00080 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 CP018901_00080 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 CP018901_00080 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 CP018901_00080 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS_VipA PF05591.12 CP018901_00081 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 CP018901_00081 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase VipB PF05943.12 CP018901_00082 - 7.4e-170 565.3 0.0 8.7e-170 565.1 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 CP018901_00082 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide GPW_gp25 PF04965.14 CP018901_00083 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 CP018901_00083 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 CP018901_00083 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) T6SS_TssF PF05947.12 CP018901_00084 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF T6SS_TssG PF06996.11 CP018901_00085 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG Phage_GPD PF05954.11 CP018901_00086 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 CP018901_00086 - 0.011 15.7 1.7 0.029 14.2 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Gp5_C PF06715.12 CP018901_00086 - 0.013 15.6 4.6 0.19 11.9 0.1 4.0 2 1 2 4 4 4 0 Gp5 C-terminal repeat (3 copies) DUF3540 PF12059.8 CP018901_00086 - 0.1 12.4 0.8 0.45 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) TCL1_MTCP1 PF01840.17 CP018901_00086 - 0.1 12.2 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 TCL1/MTCP1 family Ank_3 PF13606.6 CP018901_00087 - 2.8e-10 39.5 0.1 0.00091 19.5 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 CP018901_00087 - 3.8e-09 37.0 0.0 2.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CP018901_00087 - 1.9e-05 25.1 0.0 0.0011 19.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CP018901_00087 - 7.3e-05 23.0 0.0 2.5 8.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CP018901_00087 - 0.0034 17.6 0.3 0.13 12.7 0.0 3.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 CP018901_00088 - 6.6e-08 32.8 0.0 6.6e-08 32.8 0.0 3.0 2 1 1 3 3 3 1 Restriction endonuclease fold toxin 7 Ank_2 PF12796.7 CP018901_00089 - 1.3e-11 44.9 0.5 1.1e-06 29.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CP018901_00089 - 4.9e-10 38.8 0.4 0.0091 16.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CP018901_00089 - 0.0015 19.1 0.1 0.31 11.7 0.0 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CP018901_00089 - 0.0038 17.6 0.0 18 6.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CP018901_00089 - 0.023 15.0 0.1 1.5 9.2 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 CP018901_00090 - 1.4e-07 31.7 4.9 1.7e-07 31.5 0.0 3.6 2 1 1 3 3 3 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 CP018901_00090 - 0.57 9.9 6.5 1.6 8.5 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Ank_2 PF12796.7 CP018901_00091 - 5.5e-13 49.3 0.5 1.3e-07 32.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CP018901_00091 - 5.8e-11 41.6 0.3 0.00054 20.2 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CP018901_00091 - 1.9e-05 24.9 0.0 1.1 9.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CP018901_00091 - 6.7e-05 23.4 0.2 0.018 15.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FAM25 PF15825.5 CP018901_00091 - 0.0037 17.6 1.6 2.4 8.6 0.2 2.7 2 0 0 2 2 2 2 FAM25 family Ank_5 PF13857.6 CP018901_00091 - 0.028 14.7 0.1 0.82 10.1 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (many copies) TNT PF14021.6 CP018901_00094 - 1.5e-15 57.5 0.0 1.1e-08 35.5 0.0 2.3 2 0 0 2 2 2 2 Tuberculosis necrotizing toxin LPD7 PF18821.1 CP018901_00095 - 0.032 14.3 0.5 3.1 8.0 0.1 2.4 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 CP018901_00095 - 1.1 9.8 8.9 1.5 9.4 2.6 3.0 1 1 2 3 3 3 0 Immunity protein 59 AHH PF14412.6 CP018901_00096 - 1e-15 57.8 1.5 2e-15 56.9 1.5 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Ntox24 PF15529.6 CP018901_00099 - 0.003 17.8 1.3 0.0048 17.2 0.3 1.9 2 0 0 2 2 2 1 Bacterial toxin 24 CobN-Mg_chel PF02514.16 CP018901_00100 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Imm59 PF15597.6 CP018901_00101 - 0.054 14.0 8.6 0.12 12.9 1.7 2.2 1 1 1 2 2 2 0 Immunity protein 59 AHH PF14412.6 CP018901_00102 - 5.7e-17 61.8 2.0 1.1e-16 60.9 2.0 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 CP018901_00102 - 0.25 11.3 7.2 0.13 12.2 1.5 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF4299 PF14132.6 CP018901_00104 - 1.4e-08 34.5 0.1 1.6e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) XPG_I PF00867.18 CP018901_00104 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region Phage_GPD PF05954.11 CP018901_00106 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 CP018901_00106 - 0.081 12.6 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family BaxI_1 PF12811.7 CP018901_00108 - 0.28 10.7 13.0 0.43 10.1 12.5 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like CrgA PF06781.12 CP018901_00108 - 0.43 10.7 6.3 0.5 10.5 4.6 2.0 2 0 0 2 2 2 0 Cell division protein CrgA Peripla_BP_2 PF01497.18 CP018901_00109 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF2345 PF10106.9 CP018901_00109 - 0.029 14.3 0.4 0.27 11.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DZR PF12773.7 CP018901_00113 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 CP018901_00113 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 CP018901_00113 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rapsyn_N PF10579.9 CP018901_00114 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SprT-like PF10263.9 CP018901_00116 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 CP018901_00116 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain Phage_integrase PF00589.22 CP018901_00119 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CP018901_00119 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 CP018901_00119 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 CP018901_00119 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 CP018901_00119 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 CP018901_00119 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlaC_arch PF05377.11 CP018901_00120 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) WGR PF05406.15 CP018901_00121 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 CP018901_00121 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like YafQ_toxin PF15738.5 CP018901_00125 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 CP018901_00125 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 CP018901_00125 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 CP018901_00125 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system CCDC-167 PF15188.6 CP018901_00130 - 0.0044 17.3 0.4 0.0077 16.6 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 CP018901_00130 - 0.018 15.1 3.2 0.049 13.8 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) Sigma_reg_N PF13800.6 CP018901_00131 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5601 PF18151.1 CP018901_00132 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 CP018901_00132 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) HTH_3 PF01381.22 CP018901_00134 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 CP018901_00134 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 CP018901_00134 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 CP018901_00134 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CP018901_00134 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 CP018901_00134 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 CP018901_00134 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 CP018901_00134 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CP018901_00134 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 CP018901_00134 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 CP018901_00134 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 CP018901_00134 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 CP018901_00134 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 CP018901_00134 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 CP018901_00134 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 CP018901_00134 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 CP018901_00134 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 CP018901_00134 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 CP018901_00134 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 CP018901_00134 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain SNF2_N PF00176.23 CP020479_00001 - 4.6e-14 51.9 0.1 1.8e-13 49.9 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Eco57I PF07669.11 CP020479_00001 - 2.4e-09 37.6 1.8 4.5e-07 30.3 0.0 4.8 3 0 0 3 3 3 1 Eco57I restriction-modification methylase Helicase_C PF00271.31 CP020479_00001 - 2.2e-06 28.0 0.9 3.6e-05 24.1 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP020479_00001 - 0.0037 17.1 2.5 0.01 15.6 0.1 2.9 2 1 0 3 3 3 1 DEAD/DEAH box helicase Methyltransf_23 PF13489.6 CP020479_00001 - 0.0041 17.0 0.1 0.049 13.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CP020479_00001 - 0.0059 16.2 0.0 0.019 14.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase small domain Hydrolase PF00702.26 CP020479_00001 - 0.1 12.8 1.1 5.2 7.3 0.2 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase AbiEi_4 PF13338.6 CP020479_00002 - 6.2e-05 23.1 0.0 0.00031 20.8 0.0 2.1 3 0 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin AbiEii PF08843.11 CP020479_00003 - 5.5e-30 105.1 0.1 8e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system JmjN PF02375.17 CP020479_00004 - 1.2 9.2 3.8 17 5.5 0.1 2.7 2 1 1 3 3 3 0 jmjN domain MtrG PF04210.13 CP020479_00004 - 1.2 9.1 5.1 0.8 9.6 0.7 2.2 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G RelB PF04221.12 CP020479_00005 - 2.1e-09 37.2 0.0 2.6e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 RelB antitoxin ParE_toxin PF05016.15 CP020479_00006 - 2.7e-05 24.7 0.5 3e-05 24.5 0.5 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Apolipoprotein PF01442.18 CP020479_00007 - 0.00016 21.6 2.2 0.00016 21.6 2.2 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain PP_kinase PF02503.17 CP020479_00007 - 0.011 15.3 0.7 0.011 15.3 0.7 1.7 2 0 0 2 2 2 0 Polyphosphate kinase middle domain T3SSipB PF16535.5 CP020479_00007 - 0.025 15.0 0.3 0.053 14.0 0.3 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB Thump_like PF18096.1 CP020479_00007 - 0.046 13.6 0.6 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 THUMP domain-like Fib_alpha PF08702.10 CP020479_00007 - 7.7 6.7 9.5 1.8 8.8 5.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 CP020479_00007 - 8.3 6.8 12.9 1.9 8.8 7.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein NYN PF01936.18 CP020479_00008 - 2.8e-10 40.8 1.4 9.5e-10 39.1 1.4 1.8 1 1 0 1 1 1 1 NYN domain Tn7_Tnp_TnsA_C PF08721.11 CP020479_00008 - 0.0029 18.2 1.9 0.42 11.3 0.3 2.5 2 0 0 2 2 2 2 TnsA endonuclease C terminal TMPIT PF07851.13 CP020479_00008 - 0.078 12.2 2.2 0.11 11.7 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein ApbA PF02558.16 CP020479_00008 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Vir_act_alpha_C PF10400.9 CP020479_00008 - 0.28 11.9 1.6 0.57 10.9 1.1 1.8 1 1 1 2 2 2 0 Virulence activator alpha C-term UvrD_C PF13361.6 CP020479_00009 - 8e-16 58.3 3.4 4.2e-11 42.8 0.2 2.6 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CP020479_00009 - 2.3e-12 47.5 0.0 8.7e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CP020479_00009 - 2e-09 37.6 1.2 0.0027 17.5 0.3 3.4 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CP020479_00009 - 5.4e-09 36.0 22.6 1.6e-07 31.2 2.9 4.2 2 2 1 4 4 4 3 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 CP020479_00009 - 1.2e-06 28.2 0.0 0.055 13.3 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CP020479_00009 - 5.1e-05 23.1 0.0 0.00021 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CP020479_00009 - 0.0028 17.7 3.3 0.0028 17.7 3.3 2.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CP020479_00009 - 0.0036 16.8 0.4 1.1 8.7 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 CP020479_00009 - 0.024 14.9 0.2 0.14 12.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CP020479_00009 - 0.15 11.8 0.2 2.3 7.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Fic PF02661.18 CP020479_00011 - 3.8e-13 50.1 0.5 2.1e-12 47.8 0.0 2.4 3 0 0 3 3 3 1 Fic/DOC family Tli4_N PF18443.1 CP020479_00011 - 3.3 8.1 9.6 1.3 9.4 6.2 2.1 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain YopX PF09643.10 CP020479_00012 - 4.1e-12 46.3 6.8 3.1e-11 43.5 4.1 2.2 1 1 1 2 2 2 2 YopX protein TMF_DNA_bd PF12329.8 CP020479_00013 - 0.00073 19.5 18.5 0.00073 19.5 18.5 7.0 3 1 3 6 6 6 1 TATA element modulatory factor 1 DNA binding DUF386 PF04074.12 CP020479_00014 - 0.024 14.5 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 YhcH/YjgK/YiaL AAA_31 PF13614.6 CP020479_00015 - 8.4e-18 64.9 2.1 3.1e-11 43.5 0.0 2.7 1 1 1 3 3 3 2 AAA domain CbiA PF01656.23 CP020479_00015 - 6e-17 61.9 0.2 8.6e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 CP020479_00015 - 7.9e-15 54.8 0.3 1.3e-06 28.0 0.0 2.4 2 1 0 3 3 3 2 ATPase MipZ VirC1 PF07015.11 CP020479_00015 - 5.1e-07 29.2 0.0 7.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 VirC1 protein ParA PF10609.9 CP020479_00015 - 1.5e-06 27.9 0.2 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CLP1_P PF16575.5 CP020479_00015 - 5.2e-05 23.1 0.0 0.00091 19.1 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ArsA_ATPase PF02374.15 CP020479_00015 - 0.00018 20.8 0.3 0.0003 20.1 0.1 1.5 1 1 0 1 1 1 1 Anion-transporting ATPase SRP54 PF00448.22 CP020479_00015 - 0.00025 20.7 1.1 0.0011 18.7 0.4 2.2 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CP020479_00015 - 0.016 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CP020479_00015 - 0.016 14.6 0.0 0.038 13.4 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1188 PF06690.11 CP020479_00015 - 0.057 13.0 2.3 0.081 12.5 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1188) AAA_26 PF13500.6 CP020479_00015 - 0.089 12.6 1.2 6.3 6.6 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 CP020479_00015 - 0.098 13.2 0.6 1.3 9.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain PAC2 PF09754.9 CP020479_00015 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 PAC2 family DUF4271 PF14093.6 CP020479_00016 - 0.0013 18.7 1.3 0.0017 18.3 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) SLAC1 PF03595.17 CP020479_00016 - 0.0015 17.9 2.7 0.002 17.4 2.8 1.3 1 1 0 1 1 1 1 Voltage-dependent anion channel PEN-2 PF10251.9 CP020479_00016 - 0.0075 16.7 0.7 0.014 15.8 0.5 1.6 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase DUF3413 PF11893.8 CP020479_00016 - 0.028 13.6 2.1 0.029 13.5 1.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) DUF456 PF04306.13 CP020479_00016 - 0.033 14.5 4.7 0.058 13.7 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF456) TctB PF07331.11 CP020479_00016 - 0.17 12.1 8.2 0.32 11.3 8.2 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF1772 PF08592.11 CP020479_00016 - 0.25 11.7 2.0 0.22 11.8 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4405 PF14358.6 CP020479_00016 - 4.8 7.8 8.7 2.9 8.5 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) TSNAXIP1_N PF15739.5 CP020479_00017 - 0.012 16.0 2.3 0.015 15.7 2.3 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus CsoSCA PF08936.10 CP020479_00017 - 0.045 12.4 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase SPC12 PF06645.13 CP020479_00018 - 0.33 11.1 8.5 0.082 13.0 3.5 2.3 1 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Arteri_Gl PF00951.18 CP020479_00018 - 8.1 6.2 11.4 4.8 7.0 2.1 2.2 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein DUF4521 PF15021.6 CP020479_00019 - 0.007 16.3 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) SOAR PF16533.5 CP020479_00020 - 0.023 14.7 1.5 0.023 14.7 1.5 1.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region zf-RING_9 PF13901.6 CP020479_00020 - 0.071 13.1 3.2 0.095 12.7 3.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Pro-rich_19 PF15455.6 CP020479_00020 - 0.098 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 DUF2959 PF11172.8 CP020479_00020 - 0.21 11.7 8.6 0.048 13.8 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) DASH_Hsk3 PF08227.11 CP020479_00020 - 0.79 10.1 3.9 3.4 8.1 0.1 3.3 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like DUF1664 PF07889.12 CP020479_00020 - 1.2 9.1 7.2 13 5.9 1.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CP020479_00020 - 3.4 7.8 6.7 29 4.8 3.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SpoIIIAH PF12685.7 CP020479_00021 - 0.00058 19.7 1.1 0.0008 19.3 1.1 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein ASFV_J13L PF05568.11 CP020479_00021 - 0.0095 15.7 0.3 0.016 15.0 0.3 1.4 1 1 0 1 1 1 1 African swine fever virus J13L protein Baculo_F PF12259.8 CP020479_00022 - 0.02 13.4 0.7 0.021 13.4 0.7 1.0 1 0 0 1 1 1 0 Baculovirus F protein CcdA PF07362.12 CP020479_00022 - 0.031 14.7 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Phage_Mu_Gam PF07352.12 CP020479_00022 - 0.086 12.7 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Yae1_N PF09811.9 CP020479_00023 - 0.86 9.4 2.9 0.44 10.3 0.2 1.9 3 0 0 3 3 3 0 Essential protein Yae1, N terminal DUF5638 PF18688.1 CP020479_00026 - 0.0095 16.2 6.4 0.45 10.8 0.3 2.8 3 0 0 3 3 3 2 Family of unknown function (DUF5638) YvrJ PF12841.7 CP020479_00027 - 2.2 7.9 5.6 4.7 6.8 0.1 2.7 3 0 0 3 3 3 0 YvrJ protein family Phage_holin_6_1 PF09682.10 CP020479_00028 - 0.015 15.7 0.2 0.017 15.5 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) TMEM151 PF14857.6 CP020479_00028 - 0.029 13.3 0.0 0.031 13.2 0.0 1.0 1 0 0 1 1 1 0 TMEM151 family Mlo PF03094.15 CP020479_00028 - 0.033 12.6 0.2 0.035 12.5 0.2 1.0 1 0 0 1 1 1 0 Mlo family Na_Ala_symp PF01235.17 CP020479_00028 - 0.047 13.0 0.0 0.053 12.8 0.0 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family Yae1_N PF09811.9 CP020479_00029 - 0.42 10.3 4.8 0.15 11.8 2.0 1.7 2 0 0 2 2 2 0 Essential protein Yae1, N terminal DUF4234 PF14018.6 CP020479_00030 - 0.033 14.3 1.1 0.049 13.8 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Ribosomal_L44 PF00935.19 CP020479_00031 - 0.1 13.1 0.6 0.1 13.1 0.6 2.1 2 1 1 3 3 3 0 Ribosomal protein L44 Imm8 PF15586.6 CP020479_00032 - 0.034 14.2 0.8 0.14 12.2 0.1 2.3 2 1 0 2 2 2 0 Immunity protein 8 Orthopox_F7 PF05813.12 CP020479_00032 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Orthopoxvirus F7 protein PYST-C1 PF09690.10 CP020479_00032 - 1.1 9.0 7.2 2.7 7.8 7.2 1.6 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) T3SSipB PF16535.5 CP020479_00032 - 4.3 7.8 13.9 4.1 7.9 10.1 2.5 2 1 0 2 2 2 0 Type III cell invasion protein SipB Remorin_C PF03763.13 CP020479_00033 - 0.76 9.7 6.9 2.8 7.9 0.4 2.9 3 0 0 3 3 3 0 Remorin, C-terminal region Corona_NS3b PF03053.14 CP020479_00034 - 0.0098 15.7 0.2 0.011 15.5 0.2 1.1 1 0 0 1 1 1 1 ORF3b coronavirus protein DUF5058 PF16481.5 CP020479_00034 - 0.042 13.6 0.2 0.044 13.5 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) MscS_TM PF12794.7 CP020479_00034 - 0.052 12.4 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MBOAT_2 PF13813.6 CP020479_00034 - 0.061 13.6 0.1 0.083 13.2 0.1 1.1 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family ETRAMP PF09716.10 CP020479_00035 - 0.021 14.9 0.2 0.024 14.7 0.2 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Baculo_PEP_C PF04513.12 CP020479_00037 - 0.19 11.8 7.2 0.29 11.2 7.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B558a PF05038.13 CP020479_00038 - 0.0086 15.7 0.0 0.0099 15.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit DUF3040 PF11239.8 CP020479_00038 - 0.3 11.4 1.4 0.33 11.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF746 PF05344.11 CP020479_00039 - 0.045 13.6 0.0 0.046 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Tetraspanin PF00335.20 CP020479_00041 - 0.022 14.5 0.0 0.023 14.4 0.0 1.0 1 0 0 1 1 1 0 Tetraspanin family Saf_2TM PF18303.1 CP020479_00041 - 0.041 13.5 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain OPA3 PF07047.12 CP020479_00041 - 0.075 12.8 0.0 0.095 12.5 0.0 1.1 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) LapA_dom PF06305.11 CP020479_00041 - 0.078 12.8 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CPSase_L_D2 PF02786.17 CP020479_00042 - 0.0071 15.9 0.3 0.0097 15.4 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AAA_23 PF13476.6 CP020479_00042 - 0.074 13.6 6.5 0.1 13.1 6.0 1.5 1 1 0 1 1 1 0 AAA domain PBECR3 PF18812.1 CP020479_00042 - 0.19 11.7 6.8 0.079 12.9 3.5 2.0 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 RecG_N PF17190.4 CP020479_00042 - 0.29 11.9 3.6 0.38 11.5 0.4 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF5301 PF17225.3 CP020479_00042 - 4.5 7.8 8.1 18 5.9 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5300) Tape_meas_lam_C PF09718.10 CP020479_00043 - 0.12 12.5 0.3 0.19 11.9 0.3 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SLT PF01464.20 CP020479_00044 - 3.3e-14 52.5 0.1 4.8e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain MFS_Mycoplasma PF07672.13 CP020479_00046 - 0.0037 16.6 0.3 0.0037 16.6 0.3 1.0 1 0 0 1 1 1 1 Mycoplasma MFS transporter OSTMP1 PF09777.9 CP020479_00046 - 0.0094 15.4 0.1 0.0094 15.4 0.1 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor DUF3139 PF11337.8 CP020479_00046 - 0.0097 16.5 0.6 0.012 16.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) ATP-synt_8 PF00895.20 CP020479_00046 - 0.07 13.6 1.9 0.088 13.3 1.9 1.1 1 0 0 1 1 1 0 ATP synthase protein 8 Presenilin PF01080.17 CP020479_00046 - 1 8.0 3.9 0.93 8.2 3.3 1.3 1 1 0 1 1 1 0 Presenilin PBECR3 PF18812.1 CP020479_00047 - 0.051 13.5 3.0 0.087 12.8 3.0 1.5 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 AAA_10 PF12846.7 CP020479_00049 - 1.5e-05 24.1 0.1 0.0012 17.8 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.6 CP020479_00049 - 0.17 12.2 0.9 5.2 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CP020479_00049 - 0.91 9.6 9.9 1 9.4 5.2 3.0 2 1 0 2 2 2 0 Helicase HerA, central domain HTH_Crp_2 PF13545.6 CP020479_00050 - 0.0016 18.4 0.2 0.0059 16.6 0.1 2.1 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 CP020479_00050 - 0.0078 15.8 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Phage_rep_O PF04492.13 CP020479_00050 - 0.035 14.7 0.1 0.091 13.4 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage replication protein O Utp11 PF03998.13 CP020479_00050 - 0.039 13.9 8.7 0.067 13.1 8.7 1.4 1 0 0 1 1 1 0 Utp11 protein DUF5359 PF17313.2 CP020479_00050 - 0.048 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5359) DUF1413 PF07205.11 CP020479_00050 - 0.062 13.3 1.4 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) HLH PF00010.26 CP020479_00051 - 0.12 12.3 1.8 0.14 12.1 0.6 1.8 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain O-antigen_lig PF13425.6 CP020479_00052 - 1.7e-06 27.1 2.5 2.1e-06 26.8 2.5 1.0 1 0 0 1 1 1 1 O-antigen ligase like membrane protein CLN3 PF02487.17 CP020479_00052 - 0.00068 18.8 0.1 0.00074 18.7 0.1 1.1 1 0 0 1 1 1 1 CLN3 protein TMEM171 PF15471.6 CP020479_00052 - 0.031 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Connexin PF00029.19 CP020479_00052 - 0.061 13.1 0.4 0.089 12.5 0.4 1.2 1 0 0 1 1 1 0 Connexin DUF4834 PF16118.5 CP020479_00052 - 0.39 11.7 9.4 2.1 9.4 9.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4355 PF14265.6 CP020479_00052 - 0.51 10.6 11.2 0.7 10.1 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) AAA PF00004.29 CP020479_00053 - 4.6e-15 56.2 0.0 8e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CP020479_00053 - 1.1e-05 25.5 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CP020479_00053 - 2.8e-05 24.4 0.2 0.0051 17.1 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CP020479_00053 - 6.1e-05 23.1 0.2 0.0002 21.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CP020479_00053 - 0.00029 20.1 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CP020479_00053 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CP020479_00053 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CP020479_00053 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2120 PF09893.9 CP020479_00053 - 0.042 14.0 0.2 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) AAA_16 PF13191.6 CP020479_00053 - 0.099 13.0 0.0 3.1 8.2 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain TniB PF05621.11 CP020479_00053 - 0.19 11.1 1.1 7.9 5.8 0.1 3.0 2 1 1 3 3 3 0 Bacterial TniB protein YopX PF09643.10 CP020479_00054 - 1.5e-12 47.7 2.9 1.9e-12 47.4 2.9 1.2 1 0 0 1 1 1 1 YopX protein Telomere_reg-2 PF10193.9 CP020479_00056 - 0.13 12.7 0.6 5.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Telomere length regulation protein Snapin_Pallidin PF14712.6 CP020479_00062 - 0.79 10.2 7.9 11 6.6 0.4 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Topoisom_bac PF01131.20 CP020479_00063 - 3.7e-97 325.9 2.9 4.8e-97 325.6 2.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP020479_00063 - 1.2e-11 44.8 0.4 5.6e-11 42.6 0.1 2.4 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP020479_00063 - 2.3e-07 30.5 20.4 0.001 18.8 4.6 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP020479_00063 - 0.00043 20.5 0.2 0.69 10.2 0.0 2.4 2 0 0 2 2 2 2 zinc-ribbon Zn_ribbon_SprT PF17283.2 CP020479_00063 - 0.015 15.2 1.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Toprim_2 PF13155.6 CP020479_00063 - 0.054 13.9 0.2 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 Toprim-like Zn-ribbon_8 PF09723.10 CP020479_00063 - 0.082 13.0 0.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 CP020479_00063 - 0.1 12.5 2.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Toprim_4 PF13662.6 CP020479_00063 - 0.1 13.1 0.1 0.68 10.4 0.0 2.4 2 0 0 2 2 2 0 Toprim domain zf-ribbon_3 PF13248.6 CP020479_00063 - 0.18 11.3 1.0 12 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HTH_34 PF13601.6 CP020479_00063 - 0.25 11.6 1.1 0.77 10.0 0.1 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain TRAF6_Z2 PF18048.1 CP020479_00063 - 0.45 10.7 3.7 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS1 PF03811.13 CP020479_00063 - 0.48 10.2 3.3 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-HIT PF04438.16 CP020479_00063 - 0.61 10.0 4.2 5.9 6.8 0.4 2.5 2 0 0 2 2 2 0 HIT zinc finger zf_C2H2_10 PF18414.1 CP020479_00063 - 2.6 7.7 7.4 11 5.7 1.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger PIN_4 PF13638.6 CP020479_00063 - 4 7.7 5.5 0.89 9.8 0.5 2.4 3 0 0 3 3 3 0 PIN domain PADR1 PF08063.12 CP020479_00063 - 7.7 6.4 8.1 9.6 6.1 1.7 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-H2C2_2 PF13465.6 CP020479_00063 - 7.8 7.1 8.1 12 6.5 0.7 3.2 3 0 0 3 3 2 0 Zinc-finger double domain CoA_transf_3 PF02515.17 CP020479_00064 - 0.18 10.9 0.4 0.28 10.3 0.4 1.3 1 0 0 1 1 1 0 CoA-transferase family III Tfb5 PF06331.12 CP020479_00065 - 1.7 8.7 7.2 5.1 7.2 0.7 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 DUF3042 PF11240.8 CP020479_00066 - 8.3 6.5 6.1 18 5.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF2368 PF10166.9 CP020479_00067 - 0.59 9.7 2.9 0.35 10.5 1.0 1.6 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2368) Herpes_UL73 PF03554.13 CP020479_00067 - 2.6 8.1 10.4 0.79 9.8 4.6 2.2 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein GLF PF03275.13 CP020479_00069 - 0.021 14.5 1.0 0.021 14.5 1.0 2.2 2 1 1 3 3 3 0 UDP-galactopyranose mutase HTH_57 PF18679.1 CP020479_00069 - 0.051 13.9 0.3 0.051 13.9 0.3 2.4 2 1 0 2 2 2 0 ThcOx helix turn helix domain DUF349 PF03993.12 CP020479_00069 - 3.7 7.9 13.9 28 5.1 0.4 4.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF349) DUF1192 PF06698.11 CP020479_00071 - 5.1 7.2 15.9 0.16 12.0 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Peptidase_C101 PF16218.5 CP020479_00072 - 0.00027 20.3 6.7 0.00027 20.3 6.7 1.5 1 1 1 2 2 2 2 Peptidase family C101 HTH_45 PF14947.6 CP020479_00072 - 0.029 14.3 1.2 0.063 13.3 1.0 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix CLAMP PF14769.6 CP020479_00072 - 0.086 13.3 4.7 0.26 11.8 1.2 2.3 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF2232 PF09991.9 CP020479_00074 - 0.046 12.9 0.4 0.053 12.7 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Thioredoxin_2 PF13098.6 CP020479_00075 - 5.6e-06 26.8 2.9 8.6e-06 26.2 1.5 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CP020479_00075 - 0.00015 22.0 2.1 0.0006 20.0 0.2 2.3 2 0 0 2 2 2 1 Thioredoxin Glutaredoxin PF00462.24 CP020479_00075 - 0.0022 18.2 0.3 0.0094 16.2 0.3 2.0 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CP020479_00075 - 0.0074 16.3 0.1 0.055 13.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain HypD PF01924.16 CP020479_00075 - 0.061 12.4 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Aminopep PF10023.9 CP020479_00075 - 3.2 7.0 7.8 0.56 9.5 1.4 2.1 1 1 1 2 2 2 0 Putative aminopeptidase 4HFCP_synth PF04476.13 CP020479_00077 - 0.005 16.6 0.1 0.0092 15.7 0.1 1.4 1 0 0 1 1 1 1 4-HFC-P synthase Herpes_U30 PF04523.13 CP020479_00077 - 0.044 11.7 3.7 0.051 11.5 3.7 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 TT_ORF1 PF02956.14 CP020479_00077 - 0.14 10.8 2.1 0.14 10.8 2.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF4776 PF16003.5 CP020479_00077 - 3.4 6.6 9.6 3.8 6.4 9.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4776) LMBR1 PF04791.16 CP020479_00077 - 4.3 6.1 6.3 4.7 6.0 6.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Bacillus_HBL PF05791.11 CP020479_00078 - 0.03 14.2 1.8 0.04 13.8 1.8 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Tape_meas_lam_C PF09718.10 CP020479_00078 - 0.035 14.2 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Prefoldin_3 PF13758.6 CP020479_00078 - 0.042 13.9 1.1 0.055 13.5 1.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit Erf4 PF10256.9 CP020479_00078 - 0.09 12.9 0.9 1.1 9.4 0.5 2.3 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family KAR PF15222.6 CP020479_00080 - 0.037 14.3 2.6 2 8.8 0.5 2.1 2 0 0 2 2 2 0 Kidney androgen-regulated LRAT PF04970.13 CP020479_00081 - 0.035 14.4 0.0 0.037 14.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SNase PF00565.17 CP020479_00082 - 2.2e-26 92.4 0.3 3.2e-26 91.9 0.3 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue HipA_C PF07804.12 CP020479_00084 - 1.5e-07 31.3 0.2 6e-07 29.4 0.2 2.0 1 1 0 1 1 1 1 HipA-like C-terminal domain PI3_PI4_kinase PF00454.27 CP020479_00084 - 0.17 11.7 2.3 0.43 10.3 2.3 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DUF751 PF05421.11 CP020479_00085 - 0.0064 17.2 1.2 0.0099 16.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF751) ThrE PF06738.12 CP020479_00085 - 0.012 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter Tom22 PF04281.13 CP020479_00085 - 0.046 13.5 0.1 0.067 13.0 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Cadherin_C_2 PF16492.5 CP020479_00086 - 0.11 13.3 0.0 0.11 13.3 0.0 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RSN1_TM PF13967.6 CP020479_00088 - 0.039 13.7 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Chordopox_A13L PF05961.11 CP020479_00088 - 0.1 12.8 0.6 0.13 12.5 0.6 1.2 1 1 0 1 1 1 0 Chordopoxvirus A13L protein HipA_C PF07804.12 CP020479_00089 - 2.2e-32 112.5 0.3 3.7e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 HipA-like C-terminal domain Fic PF02661.18 CP020479_00090 - 1.1e-18 67.9 0.7 2.1e-18 67.0 0.1 1.8 2 0 0 2 2 2 1 Fic/DOC family NPV_P10 PF05531.12 CP020479_00091 - 0.034 14.6 0.3 0.046 14.2 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1246 PF06849.12 CP020479_00091 - 0.092 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) DivIC PF04977.15 CP020479_00091 - 0.1 12.4 1.7 0.14 11.9 1.7 1.4 1 1 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 CP020479_00091 - 0.25 11.6 7.0 0.37 11.0 2.7 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper TraG-D_C PF12696.7 CP020479_00092 - 4.2e-10 39.7 0.1 9.7e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP020479_00092 - 5.1e-06 25.7 0.3 0.01 14.8 0.1 2.7 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP020479_00092 - 6.5e-06 26.4 0.2 1.7e-05 25.0 0.2 1.8 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_10 PF12846.7 CP020479_00092 - 9.1e-06 24.8 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain DUF853 PF05872.12 CP020479_00092 - 0.0066 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) PAPS_reduct PF01507.19 CP020479_00092 - 0.02 14.9 0.1 0.049 13.7 0.1 1.6 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family CSM2 PF16834.5 CP020479_00093 - 0.031 13.9 1.4 0.037 13.7 0.2 1.7 2 0 0 2 2 2 0 Shu complex component Csm2, DNA-binding Ribonuc_red_lgC PF02867.15 CP020479_00093 - 0.057 11.9 0.5 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Ribonucleotide reductase, barrel domain eIF-5_eIF-2B PF01873.17 CP020479_00093 - 0.17 11.7 2.0 0.15 12.0 0.5 1.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RHH_7 PF16777.5 CP020480_00001 - 0.11 12.9 6.6 0.32 11.4 2.2 2.5 1 1 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG TMEM95 PF15203.6 CP020480_00001 - 0.12 12.0 2.6 0.099 12.3 0.5 1.8 2 0 0 2 2 2 0 TMEM95 family pRN1_helical PF13010.6 CP020480_00001 - 3.7 7.5 9.1 2.4 8.1 6.5 1.9 1 1 1 2 2 2 0 Primase helical domain Relaxase PF03432.14 CP020480_00002 - 4.2e-07 29.8 1.0 4.2e-07 29.8 1.0 2.8 2 1 1 3 3 3 1 Relaxase/Mobilisation nuclease domain DUF1673 PF07895.11 CP020480_00003 - 0.0051 16.5 3.4 0.0051 16.5 3.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1673) DUF782 PF05614.11 CP020480_00003 - 0.0068 16.8 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 Circovirus protein of unknown function (DUF782) MCU PF04678.13 CP020480_00003 - 0.047 13.8 0.3 0.07 13.2 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Acyl_transf_3 PF01757.22 CP020480_00003 - 0.074 12.1 5.8 0.16 11.0 6.0 1.4 1 1 0 1 1 1 0 Acyltransferase family Adeno_terminal PF02459.15 CP020480_00003 - 0.097 11.0 0.5 0.11 10.9 0.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF2663 PF10864.8 CP020480_00003 - 0.14 12.6 12.1 0.54 10.7 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Sugarporin_N PF11471.8 CP020480_00003 - 0.15 12.0 0.2 0.72 9.9 0.1 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF3611 PF12263.8 CP020480_00003 - 0.46 10.4 6.6 0.28 11.1 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) ECF_trnsprt PF12822.7 CP020480_00003 - 2 8.5 8.7 13 5.9 2.0 2.1 1 1 0 2 2 2 0 ECF transporter, substrate-specific component E1-E2_ATPase PF00122.20 CP020480_00003 - 3.6 7.1 4.3 7.4 6.1 0.5 2.6 1 1 2 3 3 3 0 E1-E2 ATPase Bac_export_2 PF01312.19 CP020480_00003 - 3.9 6.6 6.8 0.69 9.1 1.0 1.9 1 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family DHHC PF01529.20 CP020480_00004 - 3.4 7.8 8.5 1.8 8.7 2.9 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase AAA_31 PF13614.6 CP020480_00008 - 1.9e-11 44.2 4.9 6.7e-11 42.4 2.8 2.6 1 1 1 2 2 2 1 AAA domain MipZ PF09140.11 CP020480_00008 - 2.6e-11 43.3 1.7 3.3e-06 26.6 1.0 3.1 1 1 1 2 2 2 2 ATPase MipZ CbiA PF01656.23 CP020480_00008 - 4.3e-09 36.5 0.1 6.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CP020480_00008 - 0.00014 21.2 0.4 0.00081 18.7 0.0 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 CP020480_00008 - 0.0011 18.3 0.1 0.85 8.9 0.0 2.1 2 0 0 2 2 2 2 VirC1 protein ABC2_membrane_3 PF12698.7 CP020480_00008 - 0.0019 17.4 0.9 0.0021 17.2 0.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_24 PF13479.6 CP020480_00008 - 0.0035 17.1 1.2 0.0061 16.3 0.1 1.8 2 1 0 2 2 2 1 AAA domain ParA PF10609.9 CP020480_00008 - 0.004 16.7 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ATP_bind_1 PF03029.17 CP020480_00008 - 0.019 14.8 0.1 0.068 13.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CBP_BcsQ PF06564.12 CP020480_00008 - 0.14 11.6 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ DUF2139 PF09910.9 CP020480_00008 - 0.14 11.3 0.0 0.45 9.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) AAA_14 PF13173.6 CP020480_00008 - 0.19 11.7 7.5 0.051 13.6 1.4 2.6 1 1 2 3 3 3 0 AAA domain Fic PF02661.18 CP020480_00009 - 3.2e-15 56.8 0.1 7.3e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Fic/DOC family IL22 PF14565.6 CP020480_00009 - 0.018 15.3 0.9 1.5 9.1 0.0 2.8 2 1 1 3 3 3 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor IZUMO PF15005.6 CP020480_00009 - 1.1 9.8 7.3 1.7 9.2 0.1 2.9 2 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated CRISPR_Cas2 PF09827.9 CP020480_00011 - 0.00069 19.8 1.5 0.0022 18.1 0.0 2.3 1 1 1 2 2 2 1 CRISPR associated protein Cas2 RRM_1 PF00076.22 CP020480_00011 - 0.0021 17.8 0.5 0.0083 15.9 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPD11 PF18824.1 CP020480_00011 - 0.085 12.9 1.8 0.17 12.0 0.4 2.2 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 YopX PF09643.10 CP020480_00013 - 1.4e-08 34.8 0.5 1.4e-08 34.8 0.5 2.2 1 1 1 2 2 2 1 YopX protein Topoisom_bac PF01131.20 CP020480_00014 - 3.8e-97 325.9 2.9 4.8e-97 325.6 2.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP020480_00014 - 6.8e-12 45.5 0.3 3.4e-11 43.3 0.1 2.4 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP020480_00014 - 2.3e-07 30.5 20.4 0.001 18.8 4.6 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP020480_00014 - 0.00043 20.5 0.2 0.69 10.2 0.0 2.4 2 0 0 2 2 2 2 zinc-ribbon Zn_ribbon_SprT PF17283.2 CP020480_00014 - 0.014 15.2 1.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Toprim_2 PF13155.6 CP020480_00014 - 0.034 14.6 0.2 0.68 10.4 0.1 2.6 2 0 0 2 2 2 0 Toprim-like Zn-ribbon_8 PF09723.10 CP020480_00014 - 0.082 13.0 0.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 CP020480_00014 - 0.1 12.5 2.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Toprim_4 PF13662.6 CP020480_00014 - 0.12 12.8 0.1 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 Toprim domain zf-ribbon_3 PF13248.6 CP020480_00014 - 0.18 11.3 1.0 12 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HTH_34 PF13601.6 CP020480_00014 - 0.25 11.6 1.1 0.77 10.0 0.1 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain TRAF6_Z2 PF18048.1 CP020480_00014 - 0.45 10.6 3.7 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS1 PF03811.13 CP020480_00014 - 0.48 10.2 3.3 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-HIT PF04438.16 CP020480_00014 - 0.61 10.0 4.2 5.9 6.8 0.4 2.5 2 0 0 2 2 2 0 HIT zinc finger zf_C2H2_10 PF18414.1 CP020480_00014 - 2.6 7.7 7.4 11 5.7 1.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger PIN_4 PF13638.6 CP020480_00014 - 4.1 7.7 5.5 0.89 9.8 0.5 2.4 3 0 0 3 3 3 0 PIN domain PADR1 PF08063.12 CP020480_00014 - 7.6 6.4 8.1 9.6 6.1 1.7 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-H2C2_2 PF13465.6 CP020480_00014 - 7.9 7.1 8.1 12 6.5 0.7 3.2 3 0 0 3 3 2 0 Zinc-finger double domain Latarcin PF10279.9 CP020480_00016 - 0.016 15.6 1.6 0.66 10.4 1.6 3.5 1 1 0 1 1 1 0 Latarcin precursor Lipase_GDSL PF00657.22 CP020480_00016 - 0.033 14.2 1.1 0.067 13.2 0.9 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase T3SS_basalb_I PF17001.5 CP020480_00016 - 0.078 13.6 4.2 1.7 9.3 0.5 2.8 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cor1 PF04803.12 CP020480_00016 - 0.15 12.3 22.3 0.15 12.2 6.2 3.3 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1451 PF07295.11 CP020480_00016 - 0.25 11.3 8.8 0.2 11.7 2.5 2.5 1 1 2 3 3 3 0 Zinc-ribbon containing domain TipAS PF07739.13 CP020480_00016 - 0.36 11.4 6.4 9 6.9 0.2 3.3 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Exonuc_VII_L PF02601.15 CP020480_00016 - 0.37 10.3 10.9 0.65 9.5 2.7 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.14 CP020480_00016 - 2.8 8.3 16.8 3.5 8.0 3.1 2.8 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) TrbM PF07424.11 CP020480_00017 - 3.4e-39 134.3 1.4 4.3e-39 133.9 1.4 1.1 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP020480_00018 - 1.1e-16 61.2 0.1 1.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 LPAM_2 PF13627.6 CP020480_00018 - 0.027 14.3 3.2 0.044 13.6 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF5061 PF16587.5 CP020480_00018 - 0.15 12.2 0.1 0.19 11.8 0.1 1.3 1 1 0 1 1 1 0 17 kDa common-antigen outer membrane protein T4SS-DNA_transf PF02534.14 CP020480_00019 - 1.1e-109 367.3 0.1 1.5e-109 366.9 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP020480_00019 - 6.2e-27 94.1 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP020480_00019 - 1.4e-18 67.0 0.0 3.3e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain BRI3BP PF14965.6 CP020480_00019 - 0.1 12.1 2.6 0.11 12.0 1.5 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Njmu-R1 PF15053.6 CP020480_00021 - 0.0055 15.9 1.7 0.0081 15.3 1.7 1.3 1 0 0 1 1 1 1 Mjmu-R1-like protein family SlyX PF04102.12 CP020480_00021 - 0.5 11.0 6.8 1.7 9.3 0.9 2.4 2 0 0 2 2 2 0 SlyX PEP-utilisers_N PF05524.13 CP020480_00021 - 0.54 10.5 3.9 7.8 6.7 0.3 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Halogen_Hydrol PF10112.9 CP020480_00021 - 1.6 8.8 7.3 9.1 6.3 0.9 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF16 PF01519.16 CP020480_00021 - 4.3 7.9 11.6 3.2 8.3 2.4 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 PCRF PF03462.18 CP020480_00021 - 4.3 7.1 17.6 0.53 10.1 5.0 2.9 2 1 0 2 2 2 0 PCRF domain T2SSE PF00437.20 CP020480_00022 - 5.1e-54 183.2 0.0 6.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CP020480_00022 - 4.9e-05 23.6 0.0 9.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CP020480_00022 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP020480_00022 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP020480_00022 - 0.00062 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 CP020480_00022 - 0.0028 18.2 1.3 0.0028 18.2 1.3 1.9 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 CP020480_00022 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 CP020480_00022 - 0.003 17.0 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_15 PF13175.6 CP020480_00022 - 0.0035 17.1 2.5 0.0035 17.1 2.5 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 CP020480_00022 - 0.0041 16.9 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 CP020480_00022 - 0.0043 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.22 CP020480_00022 - 0.012 16.0 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 CP020480_00022 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CP020480_00022 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 CP020480_00022 - 0.015 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 CP020480_00022 - 0.015 15.4 1.0 0.03 14.4 0.2 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 CP020480_00022 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 CP020480_00022 - 0.021 14.6 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 CP020480_00022 - 0.023 14.1 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 CP020480_00022 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CP020480_00022 - 0.045 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 CP020480_00022 - 0.046 12.6 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 CP020480_00022 - 0.051 13.6 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.15 CP020480_00022 - 0.055 13.5 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SMC_N PF02463.19 CP020480_00022 - 0.063 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 CP020480_00022 - 0.07 12.9 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 CP020480_00022 - 0.073 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 CP020480_00022 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 CP020480_00022 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 CP020480_00022 - 0.091 12.8 0.3 0.21 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain GvpD PF07088.11 CP020480_00022 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 CP020480_00022 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 CP020480_00022 - 0.12 12.6 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CP020480_00022 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MORN_2 PF07661.13 CP020480_00023 - 0.39 11.1 2.9 2.8 8.4 0.6 2.8 2 0 0 2 2 2 0 MORN repeat variant Ribosomal_S13 PF00416.22 CP020480_00023 - 0.83 10.1 4.2 17 5.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S13/S18 TrbI PF03743.14 CP020480_00024 - 2.2e-47 161.4 0.1 2.5e-47 161.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein DUF5345 PF17280.2 CP020480_00025 - 0.01 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF3671 PF12420.8 CP020480_00025 - 0.029 14.4 0.2 0.036 14.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function Cyt_bd_oxida_I PF01654.17 CP020480_00025 - 0.074 11.7 0.0 0.079 11.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I PAP_PilO PF06864.12 CP020480_00025 - 0.12 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) AIF_C PF14721.6 CP020480_00025 - 0.19 12.1 2.0 0.23 11.8 0.4 1.8 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Vpu PF00558.19 CP020480_00025 - 1.5 8.7 5.5 5.1 6.9 5.4 1.8 1 1 0 1 1 1 0 Vpu protein CagX PF03524.15 CP020480_00026 - 7.1e-54 182.7 0.7 1.4e-53 181.7 0.7 1.5 1 1 0 1 1 1 1 Conjugal transfer protein VirB8 PF04335.13 CP020480_00027 - 8.4e-50 169.6 0.1 1e-49 169.3 0.1 1.0 1 0 0 1 1 1 1 VirB8 protein Wzz PF02706.15 CP020480_00027 - 2.4 8.5 6.7 2.8 8.3 3.2 2.5 2 1 0 2 2 2 0 Chain length determinant protein VASP_tetra PF08776.11 CP020480_00028 - 0.063 12.9 6.4 0.16 11.5 6.4 1.7 1 0 0 1 1 1 0 VASP tetramerisation domain TrbL PF04610.14 CP020480_00030 - 1.2e-32 113.5 25.3 1.6e-32 113.0 25.3 1.3 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein DUF2070 PF09843.9 CP020480_00030 - 0.45 8.7 16.6 0.69 8.1 16.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AIM3 PF17096.5 CP020480_00030 - 5.4 8.0 7.0 9.6 7.2 7.0 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF412 PF04217.13 CP020480_00030 - 5.6 6.9 10.8 17 5.3 6.6 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF412 T4SS PF07996.11 CP020480_00031 - 2e-23 83.9 15.9 2.4e-23 83.6 15.9 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins CHASE4 PF05228.13 CP020480_00031 - 0.051 13.8 5.7 1 9.6 0.2 2.8 2 1 1 3 3 3 0 CHASE4 domain AChE_tetra PF08674.10 CP020480_00031 - 0.096 12.4 1.2 0.5 10.1 0.1 2.3 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain zf-RING_6 PF14835.6 CP020480_00031 - 0.12 12.2 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein KMP11 PF03037.16 CP020480_00031 - 0.13 13.1 3.2 0.31 11.8 0.0 2.9 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 PCRF PF03462.18 CP020480_00031 - 0.22 11.3 12.0 2.7 7.8 0.4 2.2 2 0 0 2 2 2 0 PCRF domain Med8 PF10232.9 CP020480_00031 - 0.27 10.8 9.0 0.027 14.1 3.9 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1474 PF07342.11 CP020480_00031 - 1.3 9.5 5.1 0.42 11.2 1.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1474) Phage_pRha PF09669.10 CP020480_00032 - 1.4e-29 102.4 0.0 2.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) CagE_TrbE_VirB PF03135.14 CP020480_00033 - 2.5e-43 148.6 0.5 6.2e-43 147.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP020480_00033 - 1.2e-19 70.3 2.0 2.1e-19 69.5 2.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 CP020480_00034 - 2.3e-16 59.8 8.3 2.5e-16 59.7 8.3 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family ThrE PF06738.12 CP020480_00034 - 0.025 14.0 2.1 0.029 13.8 2.1 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF2062 PF09835.9 CP020480_00034 - 1.4 8.7 7.8 2 8.3 7.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP020480_00036 - 0.0005 20.2 1.3 0.00061 19.9 0.1 1.7 2 0 0 2 2 2 1 CRISPR associated protein Cas2 Resolvase PF00239.21 CP020480_00037 - 1e-32 113.2 0.6 1.3e-32 112.9 0.6 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP020480_00037 - 0.0011 18.6 1.4 0.12 12.1 0.1 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain Mu-like_Pro PF10123.9 CP020480_00037 - 0.12 11.9 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Pox_A_type_inc PF04508.12 CP020480_00037 - 8.5 6.4 9.6 0.19 11.6 0.8 3.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SseC PF04888.12 CP020480_00038 - 0.0012 18.6 1.4 0.0012 18.6 1.4 1.8 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Leu_Phe_trans PF03588.14 CP020480_00038 - 0.034 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase T2SSF PF00482.23 CP020480_00038 - 0.18 11.8 0.1 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3185 PF11381.8 CP020480_00038 - 0.19 11.7 9.4 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2207 PF09972.9 CP020480_00038 - 6.4 5.4 16.4 0.089 11.5 1.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) AAA_25 PF13481.6 CP020480_00039 - 6.7e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP020480_00039 - 0.00036 20.0 0.0 0.0021 17.4 0.0 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP020480_00039 - 0.0014 18.4 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP020480_00039 - 0.012 15.0 0.0 0.044 13.1 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA PF00004.29 CP020480_00039 - 0.076 13.4 0.3 0.89 10.0 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP020480_00039 - 0.19 11.8 2.8 1.7 8.7 2.8 2.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Toprim_3 PF13362.6 CP020480_00040 - 4.6e-09 36.5 0.0 7.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 CP020480_00040 - 0.001 19.5 0.1 0.0023 18.4 0.1 1.5 1 0 0 1 1 1 1 Toprim domain Fic PF02661.18 CP020480_00041 - 3.3e-17 63.2 0.1 9.2e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family MAS20 PF02064.15 CP020480_00042 - 0.22 11.6 7.6 0.28 11.3 0.1 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor ANAPC4 PF12896.7 CP020480_00043 - 0.027 14.0 0.1 0.034 13.6 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 MSG PF02349.15 CP020480_00043 - 0.071 13.3 4.6 0.094 12.9 4.6 1.2 1 0 0 1 1 1 0 Major surface glycoprotein EssA PF10661.9 CP020480_00044 - 0.18 11.6 8.8 0.16 11.8 7.9 1.3 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA GTP_EFTU PF00009.27 CP020775_00001 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP020775_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP020775_00001 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP020775_00001 - 3e-12 46.4 0.1 6.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP020775_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP020775_00001 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP020775_00001 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP020775_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP020775_00001 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 CP020775_00002 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CP020775_00002 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CP020775_00002 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 CP020775_00003 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 CP020775_00004 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP020775_00004 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 CP020775_00005 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP020775_00005 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP020775_00005 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 CP020775_00005 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 CP020775_00005 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 CP020775_00005 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 CP020775_00005 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP020775_00005 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 CP020775_00005 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 CP020775_00006 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP020775_00006 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP020775_00006 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP020775_00006 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP020775_00006 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP020775_00007 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP020775_00007 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP020775_00008 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP020775_00008 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP020775_00008 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP020775_00008 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP020775_00008 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP020775_00009 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP020775_00010 - 3e-16 59.1 2.6 4.1e-16 58.6 0.1 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP020775_00010 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP020775_00010 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP020775_00010 - 8.9e-06 25.6 1.8 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP020775_00010 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 CP020775_00011 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 CP020775_00011 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 CP020775_00011 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 CP020775_00012 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP020775_00012 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 CP020775_00012 - 0.0083 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 CP020775_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP020775_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP020775_00014 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP020775_00014 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP020775_00014 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP020775_00014 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 CP020775_00015 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 CP020775_00015 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 CP020775_00015 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 CP020775_00017 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 CP020775_00018 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP020775_00018 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP020775_00018 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP020775_00018 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP020775_00019 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 CP020775_00020 - 0.0019 18.2 0.5 0.0023 18.0 0.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 CP020775_00020 - 0.14 12.5 3.0 0.19 12.1 3.0 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 CP020775_00020 - 1.1 9.2 4.2 2 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP020775_00022 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system AAA_25 PF13481.6 CP020775_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP020775_00023 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP020775_00023 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 CP020775_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CP020775_00023 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP020775_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 CP020775_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 CP020775_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP020775_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP020775_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP020775_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP020775_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP020775_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP020775_00027 - 3.4e-11 43.2 3.7 4e-11 43.0 3.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP020775_00027 - 0.12 12.2 4.4 0.18 11.6 4.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP020775_00028 - 1.7e-50 172.0 0.4 3.9e-50 170.8 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP020775_00028 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 CP020775_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 CP020775_00029 - 6.6e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP020775_00029 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 CP020775_00029 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) FapA PF03961.13 CP020775_00030 - 0.0039 15.9 6.9 0.0039 15.9 6.9 1.6 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 CP020775_00030 - 0.028 14.3 4.0 0.028 14.3 4.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Fib_alpha PF08702.10 CP020775_00030 - 0.6 10.3 12.2 0.061 13.5 4.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CP020775_00030 - 1.7 8.4 11.6 0.92 9.3 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator Striatin PF08232.12 CP020775_00030 - 4.6 7.8 9.6 14 6.2 9.6 1.9 1 1 0 1 1 1 0 Striatin family Syntaxin-6_N PF09177.11 CP020775_00030 - 9.3 6.9 10.2 1.8 9.2 4.5 2.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal SSB PF00436.25 CP020775_00032 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP020775_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP020775_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP020775_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP020775_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP020775_00034 - 8.6e-29 101.4 13.7 1.2e-28 100.9 13.7 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP020775_00034 - 0.006 16.7 1.1 0.021 15.0 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 CP020775_00034 - 0.018 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 CP020775_00034 - 0.041 14.6 11.0 0.031 15.0 4.9 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3752 PF12572.8 CP020775_00034 - 1.4 9.5 6.4 9.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) THOC7 PF05615.13 CP020775_00034 - 2.8 8.2 12.1 1.7 9.0 0.2 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 Snapin_Pallidin PF14712.6 CP020775_00034 - 4.8 7.7 10.3 1.9 8.9 5.5 2.7 2 1 0 2 2 2 0 Snapin/Pallidin TrbL PF04610.14 CP020775_00035 - 3.3e-29 102.2 32.7 3.3e-29 102.2 32.7 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP020775_00035 - 0.087 12.6 1.7 0.49 10.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP020775_00035 - 1.7 9.6 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP020775_00036 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP020775_00036 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP020775_00037 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP020775_00037 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP020775_00038 - 9.4e-56 188.9 1.6 1.6e-55 188.2 1.6 1.3 1 1 0 1 1 1 1 Conjugal transfer protein Rho_RNA_bind PF07497.12 CP020775_00038 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 CP020775_00039 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP020775_00039 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP020775_00040 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP020775_00040 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP020775_00040 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP020775_00040 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP020775_00040 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP020775_00040 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CP020775_00040 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CP020775_00040 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP020775_00040 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP020775_00040 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP020775_00040 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP020775_00040 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 CP020775_00040 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 CP020775_00040 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CP020775_00040 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 CP020775_00040 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 CP020775_00040 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 CP020775_00040 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CP020775_00040 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 CP020775_00040 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CP020775_00040 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 CP020775_00040 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP020775_00040 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP020775_00040 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP020775_00040 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP020775_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP020775_00040 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP020775_00040 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP020775_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP020775_00040 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP020775_00040 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP020775_00041 - 8.4e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP020775_00041 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP020775_00041 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 CP020775_00041 - 0.19 11.8 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 CP020775_00042 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP020775_00042 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 CP020775_00043 - 2.4e-38 131.5 1.9 3.1e-38 131.2 1.9 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 CP020775_00043 - 0.21 10.6 0.1 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal PRELI PF04707.14 CP020775_00044 - 0.041 13.7 0.4 0.041 13.7 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Rsd_AlgQ PF04353.13 CP020775_00044 - 0.82 9.6 6.3 0.24 11.4 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ KH_5 PF13184.6 CP020775_00045 - 0.00035 20.6 0.5 0.00039 20.5 0.5 1.0 1 0 0 1 1 1 1 NusA-like KH domain CdhD PF03599.16 CP020775_00046 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 CP020775_00046 - 0.028 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 CP020775_00046 - 0.12 12.6 0.1 0.12 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized YnfE-like DUF1461 PF07314.11 CP020775_00047 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 CP020775_00048 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP020775_00048 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP020775_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP020775_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP020775_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP020775_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP020775_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP020775_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP020775_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP020775_00048 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP020775_00048 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP020775_00048 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP020775_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP020775_00048 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP020775_00048 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP020775_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP020775_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP020775_00049 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP020775_00049 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain HicB_lk_antitox PF15919.5 CP022078_00002 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 CP022078_00002 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 CP022078_00003 - 1.7e-15 57.1 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP022078_00003 - 0.00083 18.8 0.0 0.0041 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP022078_00003 - 0.0013 18.5 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CP022078_00003 - 0.003 17.3 1.1 0.009 15.7 0.2 2.1 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 CP022078_00003 - 0.009 15.4 0.0 0.062 12.6 0.0 2.5 2 1 0 2 2 2 1 KaiC CbiA PF01656.23 CP022078_00003 - 0.19 11.8 1.3 0.63 10.1 1.3 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 CP022078_00004 - 0.012 15.5 0.4 0.02 14.7 0.4 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 CP022078_00006 - 2.4e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP022078_00006 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP022078_00006 - 0.051 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP022078_00006 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP022078_00007 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP022078_00007 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP022078_00009 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP022078_00009 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP022078_00010 - 7.6e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP022078_00010 - 1.5e-20 73.2 1.0 2.6e-20 72.4 1.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 CP022078_00010 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 CP022078_00010 - 0.038 14.1 5.5 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 CP022078_00011 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 CP022078_00011 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 CP022078_00011 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 CP022078_00011 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 CP022078_00011 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 CP022078_00012 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 CP022078_00013 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP022078_00014 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP022078_00014 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP022078_00014 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP022078_00014 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP022078_00015 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP022078_00015 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP022078_00015 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP022078_00015 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP022078_00015 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 CP022078_00015 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 CP022078_00015 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 CP022078_00015 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 CP022078_00016 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP022078_00016 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP022078_00016 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP022078_00017 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP022078_00017 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP022078_00018 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP022078_00018 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP022078_00019 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP022078_00019 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP022078_00020 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP022078_00020 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP022078_00021 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP022078_00021 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP022078_00021 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP022078_00021 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP022078_00021 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP022078_00021 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP022078_00021 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP022078_00021 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP022078_00021 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP022078_00021 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP022078_00021 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP022078_00021 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP022078_00021 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP022078_00021 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP022078_00021 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP022078_00021 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP022078_00021 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP022078_00021 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP022078_00021 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP022078_00021 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP022078_00021 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP022078_00021 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP022078_00021 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP022078_00021 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP022078_00021 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP022078_00021 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP022078_00021 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP022078_00021 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP022078_00021 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP022078_00021 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP022078_00021 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP022078_00022 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP022078_00022 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP022078_00022 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP022078_00022 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP022078_00023 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP022078_00023 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP022078_00023 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP022078_00023 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP022078_00024 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP022078_00025 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP022078_00025 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP022078_00025 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP022078_00027 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP022078_00028 - 1.4e-97 327.4 8.2 1.9e-97 326.9 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP022078_00028 - 3.7e-12 46.4 2.7 5.7e-12 45.8 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP022078_00028 - 0.05 13.4 2.1 0.14 12.0 2.1 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP022078_00028 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon EF-hand_8 PF13833.6 CP022078_00028 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 CP022078_00028 - 0.34 11.1 3.3 0.78 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 CP022078_00029 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP022078_00029 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 CP022078_00031 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP022078_00031 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP022078_00031 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP022078_00031 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP022078_00031 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP022078_00031 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP022078_00031 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP022078_00031 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP022078_00031 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF5442 PF17514.2 CP022078_00032 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 CP022078_00034 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP022078_00034 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 CP022078_00035 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP022078_00035 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 CP022078_00036 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 CP022078_00037 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP022078_00037 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP022078_00037 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP022078_00037 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP022078_00037 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP022078_00037 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP022078_00037 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 CP022078_00038 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP022078_00038 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP022078_00038 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP022078_00038 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP022078_00038 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP022078_00039 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP022078_00039 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP022078_00040 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP022078_00040 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP022078_00040 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP022078_00040 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP022078_00040 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP022078_00041 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP022078_00042 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP022078_00042 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP022078_00042 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP022078_00042 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP022078_00042 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 CP022078_00043 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP022078_00043 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 CP022078_00044 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP022078_00045 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP022078_00045 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP022078_00045 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP022078_00045 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP022078_00045 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 CP022078_00046 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 CP022078_00046 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 CP022078_00046 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 CP022078_00049 - 2.4e-08 34.2 0.1 6.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 CP022078_00049 - 0.016 15.4 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein 5_3_exonuc PF01367.20 CP022078_00049 - 0.33 11.6 2.5 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP022078_00050 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 CP022078_00050 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 CP022078_00051 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 CP022078_00052 - 4.3e-19 68.9 4.7 4.9e-19 68.7 4.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CP022078_00052 - 3.7e-18 65.8 0.5 3.7e-18 65.8 0.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CP022078_00052 - 1.3e-06 27.4 0.6 1.7e-06 27.1 0.6 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CP022078_00052 - 0.072 12.4 0.0 0.21 10.9 0.0 1.7 1 1 1 2 2 2 0 Kinase-like W2 PF02020.18 CP022471_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP022471_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 CP022471_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP022471_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 CP022471_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 CP022471_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP022471_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP022471_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP022471_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP022471_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP022471_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP022471_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 CP022471_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP022471_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP022471_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP022471_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP022471_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP022471_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP022471_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP022471_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP022471_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP022471_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP022471_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP022471_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP022471_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 CP022471_00009 - 1.6e-16 60.0 0.9 4.1e-16 58.6 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP022471_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP022471_00009 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP022471_00009 - 7.8e-06 25.8 1.5 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP022471_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 CP022471_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP022471_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 CP022471_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP022471_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP022471_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 CP022471_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 CP022471_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 CP022471_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE ESP PF16590.5 CP022471_00013 - 0.55 10.5 4.6 0.27 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 CP022471_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 CP022471_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP022471_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP022471_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP022471_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP022471_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 CP022471_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 CP022471_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 CP022471_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 CP022471_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 CP022471_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 CP022471_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 CP022471_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP022471_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP022471_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP022471_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP022471_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP022471_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 CP022471_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CP022471_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 CP022471_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 CP022471_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 CP022471_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP022471_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP022471_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 CP022471_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 CP022471_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 CP022471_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 CP022471_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP022471_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP022471_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP022471_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 CP022471_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 CP022471_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 CP022471_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 CP022471_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CP022471_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 CP022471_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 CP022471_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 CP022471_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 CP022471_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP022471_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP022471_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 CP022471_00033 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP022471_00033 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 CP022471_00033 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 CP022471_00033 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 CP022471_00033 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 CP022471_00033 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 CP022471_00033 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 CP022471_00033 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 CP022471_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP022471_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 CP022471_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 CP022471_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 CP022471_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 CP022471_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP022471_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP022471_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 CP022471_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 CP022471_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP022471_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP022471_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP022471_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP022471_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP022471_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP022471_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP022471_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP022471_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 CP022471_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP022471_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP022471_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP022471_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP022471_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CP022471_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 CP022471_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CP022471_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CP022471_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 CP022471_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CP022471_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 CP022471_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 CP022471_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 CP022471_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CP022471_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP022471_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP022471_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP022471_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 CP022471_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 CP022471_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CP022471_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 CP022471_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP022471_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP022471_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 CP022471_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP022471_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP022471_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 CP022471_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 CP022471_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 CP022471_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 CP022471_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 CP022471_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 CP022471_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP022471_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 CP022471_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 CP022471_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 CP022471_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 CP022471_00046 - 5.7e-97 325.3 8.0 8e-97 324.8 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP022471_00046 - 5.5e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP022471_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP022471_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP022471_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP022471_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP022471_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP022471_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP022471_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP022471_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP022471_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP022471_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP022471_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP022471_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP022471_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP022471_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP022471_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP022471_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP022471_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 CP022471_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP022471_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP022471_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP022471_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP022471_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP022471_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP022471_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP022471_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP022471_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 CP022471_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 CP022471_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) PDDEXK_4 PF14281.6 CP023447_00001 - 3e-38 131.8 13.1 3e-38 131.8 13.1 2.8 3 0 0 3 3 3 2 PD-(D/E)XK nuclease superfamily Eco57I PF07669.11 CP023447_00002 - 2.1e-19 70.0 0.1 1.2e-18 67.5 0.1 2.4 1 0 0 1 1 1 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 CP023447_00002 - 1.8e-12 47.4 1.7 1.8e-12 47.4 1.7 3.9 4 1 0 4 4 4 1 TaqI-like C-terminal specificity domain Mrr_cat PF04471.12 CP023447_00002 - 0.018 15.1 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Restriction endonuclease ACP_PD PF04336.12 CP023447_00002 - 0.019 15.4 0.2 1.2 9.6 0.1 3.6 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase DUF4756 PF15948.5 CP023447_00002 - 0.41 10.5 7.1 0.089 12.6 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) Pentapeptide_3 PF13576.6 CP023447_00003 - 6.7e-11 42.2 11.9 4.9e-09 36.2 2.3 5.6 4 2 1 5 5 5 3 Pentapeptide repeats (9 copies) SIMPL PF04402.14 CP023447_00004 - 3.7e-14 53.7 0.6 4.5e-14 53.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF4116 PF13475.6 CP023447_00004 - 0.036 13.8 1.6 0.036 13.8 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) ATR13 PF16829.5 CP023447_00004 - 0.081 13.3 0.5 0.88 10.0 0.0 2.5 2 1 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Nudix_N PF12535.8 CP023447_00004 - 0.1 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF3139 PF11337.8 CP023447_00004 - 0.91 10.2 8.8 0.14 12.8 1.7 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3139) MFS_1 PF07690.16 CP023447_00005 - 1.1e-42 146.2 39.9 1.1e-42 146.2 39.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CP023447_00005 - 3.9e-10 39.2 8.9 3.9e-10 39.2 8.9 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 CP023447_00005 - 2.5e-06 26.2 18.2 3e-06 25.9 18.2 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 CP023447_00005 - 1.2e-05 24.0 43.0 0.00059 18.5 22.9 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein DUF2130 PF09903.9 CP023447_00006 - 1.7e-46 158.6 15.9 1.7e-46 158.6 15.9 3.8 1 1 3 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2130) zf-ribbon_3 PF13248.6 CP023447_00006 - 0.19 11.2 0.9 0.3 10.5 0.1 1.6 2 0 0 2 2 2 0 zinc-ribbon domain RNA_pol_N PF01194.17 CP023447_00006 - 0.53 10.6 2.0 3.7 7.9 0.0 3.4 4 0 0 4 4 4 0 RNA polymerases N / 8 kDa subunit zf-ACC PF17848.1 CP023447_00006 - 1.6 8.9 5.6 1.7 8.8 0.3 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Cytochrom_C PF00034.21 CP023447_00007 - 3.7e-14 53.6 0.0 1.8e-10 41.8 0.0 3.1 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 CP023447_00007 - 5.7e-11 42.6 0.0 2.8e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 CP023447_00007 - 0.016 15.2 0.0 3.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_C550 PF14495.6 CP023447_00007 - 0.022 14.5 0.7 0.11 12.3 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 CP023447_00007 - 0.042 13.6 0.3 7.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 CP023447_00007 - 0.094 13.2 0.1 20 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c3 DUF3365 PF11845.8 CP023447_00007 - 0.19 12.1 0.2 3.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3365) Peptidase_S49_N PF08496.10 CP023447_00008 - 0.034 14.2 0.3 0.068 13.2 0.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GTP_EFTU PF00009.27 CP023447_00009 - 2.2e-54 184.0 0.4 3.5e-54 183.3 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CP023447_00009 - 2.8e-22 78.6 0.0 7.1e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CP023447_00009 - 9.2e-11 42.0 1.5 2.4e-10 40.7 1.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CP023447_00009 - 8.2e-07 29.1 0.4 1.6e-06 28.2 0.4 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 CP023447_00009 - 0.00062 19.1 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 CP023447_00009 - 0.0046 17.0 0.1 0.05 13.7 0.1 2.2 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 CP023447_00009 - 0.011 15.3 0.9 0.2 11.2 0.2 3.2 3 1 0 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 CP023447_00009 - 0.049 13.1 1.0 0.12 11.8 0.1 2.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 CP023447_00009 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family EFG_II PF14492.6 CP023447_00009 - 0.085 13.0 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II PTS_EIIA_2 PF00359.22 CP023447_00010 - 0.00096 19.1 2.8 0.0016 18.4 2.7 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FANCI_S2 PF14676.6 CP023447_00010 - 0.028 14.7 0.9 0.04 14.2 0.9 1.3 1 1 0 1 1 1 0 FANCI solenoid 2 Rotamase PF00639.21 CP023447_00010 - 0.087 13.8 0.1 0.11 13.4 0.1 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Flg_hook PF02120.16 CP023447_00011 - 2.2e-14 53.1 1.0 1.2e-13 50.7 0.3 2.6 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK FlgD_ig PF13860.6 CP023447_00012 - 1.8e-18 66.1 0.1 5.2e-18 64.7 0.1 1.8 1 0 0 1 1 1 1 FlgD Ig-like domain FlgD PF03963.14 CP023447_00012 - 1.1e-16 60.9 11.6 1.1e-16 60.9 11.6 2.3 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region FLgD_tudor PF13861.6 CP023447_00012 - 1.8e-05 24.9 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 FlgD Tudor-like domain Flg_bbr_C PF06429.13 CP023447_00013 - 1.2e-19 70.1 4.4 3.4e-19 68.7 1.8 2.9 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 CP023447_00013 - 7.3e-08 32.2 1.9 2.7e-07 30.4 1.9 2.1 2 0 0 2 2 2 1 Flagella basal body rod protein VWA_N PF08399.11 CP023447_00013 - 0.046 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 VWA N-terminal DUF3659 PF12396.8 CP023447_00013 - 0.13 12.1 0.2 41 4.2 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3659) FapA PF03961.13 CP023447_00014 - 4.3e-54 183.8 24.2 4.3e-54 183.8 24.2 1.3 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ribosomal_L1 PF00687.21 CP023447_00015 - 0.013 15.2 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family Rep_4 PF05797.11 CP023447_00015 - 0.021 14.0 0.5 0.037 13.1 0.3 1.3 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Hemerythrin PF01814.23 CP023447_00016 - 5.9e-08 33.4 3.1 5.9e-08 33.4 3.1 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain CC2D2AN-C2 PF15625.6 CP023447_00016 - 0.09 12.5 0.1 0.88 9.3 0.0 2.0 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain PulA_N1 PF17999.1 CP023447_00016 - 0.57 11.0 10.4 0.098 13.4 1.8 2.8 2 1 1 3 3 3 0 Pullulanase N1-terminal domain RPA_interact_C PF14768.6 CP023447_00016 - 4.5 7.9 9.8 4.4 7.9 0.6 3.2 2 2 1 3 3 3 0 Replication protein A interacting C-terminal Na_sulph_symp PF00939.19 CP023447_00017 - 3.4e-25 89.0 0.1 3.9e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CP023447_00017 - 0.014 14.6 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter Na_sulph_symp PF00939.19 CP023447_00018 - 4e-09 36.0 1.0 6.8e-09 35.3 1.0 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region ETRAMP PF09716.10 CP023447_00018 - 0.026 14.6 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Na_sulph_symp PF00939.19 CP023447_00019 - 1.9e-14 53.6 4.1 1.9e-14 53.6 4.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CP023447_00019 - 0.0066 15.7 4.0 0.0085 15.3 4.0 1.3 1 0 0 1 1 1 1 Citrate transporter AGTRAP PF06396.11 CP023447_00019 - 0.095 12.5 1.3 0.1 12.4 1.3 1.0 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Na_sulph_symp PF00939.19 CP023447_00020 - 1.9e-14 53.6 11.4 1.9e-14 53.6 11.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region tRNA_Me_trans PF03054.16 CP023447_00021 - 1.2e-108 363.1 1.7 1.4e-108 362.9 1.7 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ATP_bind_3 PF01171.20 CP023447_00021 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 PP-loop family ThiI PF02568.14 CP023447_00021 - 1.4e-06 28.1 0.0 3.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 CP023447_00021 - 2.5e-06 27.2 0.1 8.4e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 CP023447_00021 - 3.5e-05 23.0 0.0 0.00049 19.3 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Arginosuc_synth PF00764.19 CP023447_00021 - 0.00027 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 CP023447_00021 - 0.031 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Lysine_decarbox PF03641.14 CP023447_00022 - 2.8e-25 88.9 0.0 2.9e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CP023447_00022 - 0.09 12.4 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster4 family LDcluster4 PF18306.1 CP023447_00023 - 7.8e-06 25.6 0.1 9.3e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 CP023447_00023 - 0.00045 19.5 0.0 0.00046 19.5 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A SKI PF01202.22 CP023447_00023 - 0.029 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase Peptidase_C39 PF03412.15 CP023447_00028 - 2e-16 60.0 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 CP023447_00028 - 0.00052 20.0 0.0 0.00072 19.6 0.0 1.1 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 AHJR-like PF18743.1 CP023447_00028 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 REase_AHJR-like DUF3335 PF11814.8 CP023447_00028 - 0.1 12.1 0.0 7.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase_C39 like family FliMN_C PF01052.20 CP023447_00029 - 4.6e-21 74.6 1.5 7.2e-21 74.0 1.5 1.3 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliM PF02154.15 CP023447_00030 - 4.8e-75 251.7 1.4 6.9e-75 251.2 1.4 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 CP023447_00030 - 8e-14 51.4 0.3 1.3e-13 50.7 0.3 1.4 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term DUF3567 PF12091.8 CP023447_00030 - 0.029 14.5 1.3 0.15 12.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) 7TM_GPCR_Sri PF10327.9 CP023447_00030 - 0.045 12.9 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Pertactin PF03212.14 CP023447_00030 - 0.085 12.8 0.0 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Pertactin Sld5 PF05916.11 CP023447_00030 - 0.14 12.6 4.6 0.6 10.6 0.2 2.6 2 1 0 2 2 2 0 GINS complex protein Sigma70_r4 PF04545.16 CP023447_00031 - 2.9e-18 65.1 2.8 8.2e-18 63.7 2.8 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 CP023447_00031 - 1.7e-10 40.5 0.0 2.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 CP023447_00031 - 1.6e-08 34.1 2.3 1.6e-08 34.1 2.3 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 CP023447_00031 - 0.00075 19.6 5.5 0.0019 18.3 0.2 3.1 3 1 0 3 3 3 1 Sigma-70 region 3 HTH_23 PF13384.6 CP023447_00031 - 0.0017 18.1 0.1 0.0037 17.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 CP023447_00031 - 0.0018 18.5 4.1 0.0018 18.5 4.1 2.5 3 1 0 3 3 2 1 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.7 CP023447_00031 - 0.0027 17.5 0.0 0.0058 16.5 0.0 1.5 1 1 0 1 1 1 1 MarR family HTH_37 PF13744.6 CP023447_00031 - 0.016 15.1 0.5 0.043 13.8 0.5 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Sds3 PF08598.11 CP023447_00031 - 0.028 14.4 9.2 0.051 13.6 9.2 1.4 1 0 0 1 1 1 0 Sds3-like HTH_5 PF01022.20 CP023447_00031 - 0.036 13.9 0.2 0.093 12.6 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR PF01047.22 CP023447_00031 - 0.04 13.9 2.5 0.042 13.8 0.4 2.1 2 0 0 2 2 2 0 MarR family GerE PF00196.19 CP023447_00031 - 0.041 13.4 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family IF-2B PF01008.17 CP023447_00031 - 0.095 11.9 4.0 1.2 8.3 4.0 2.0 1 1 0 1 1 1 0 Initiation factor 2 subunit family TrmB PF01978.19 CP023447_00031 - 0.11 12.4 1.3 0.26 11.2 0.4 2.1 2 1 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_ECF PF07638.11 CP023447_00031 - 0.14 12.0 5.8 2 8.3 5.8 2.1 1 1 0 1 1 1 0 ECF sigma factor HTH_WhiA PF02650.14 CP023447_00031 - 0.15 12.4 8.4 0.046 14.1 4.7 2.1 2 1 0 2 2 2 0 WhiA C-terminal HTH domain DAPDH_C PF16654.5 CP023447_00031 - 0.15 11.9 1.7 0.33 10.8 0.3 2.0 1 1 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Glyco_hydro_65m PF03632.15 CP023447_00031 - 0.21 10.4 1.8 0.37 9.6 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 65 central catalytic domain Clr5 PF14420.6 CP023447_00031 - 2.5 8.4 5.8 1.4 9.2 0.5 2.8 3 0 0 3 3 3 0 Clr5 domain Hema_stalk PF08720.10 CP023447_00032 - 0.002 17.8 0.1 0.0026 17.5 0.1 1.2 1 0 0 1 1 1 1 Influenza C hemagglutinin stalk DUF5531 PF17671.1 CP023447_00032 - 0.04 13.8 2.6 0.056 13.3 2.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5531) Neur_chan_memb PF02932.16 CP023447_00032 - 0.11 12.5 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ParA PF10609.9 CP023447_00033 - 3.1e-26 92.3 1.4 1.2e-25 90.4 1.4 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 CP023447_00033 - 2e-19 70.2 0.5 3.7e-19 69.3 0.5 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CP023447_00033 - 2.8e-18 66.2 0.0 5.9e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CP023447_00033 - 7.6e-12 45.2 1.2 1.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 CP023447_00033 - 4.9e-07 29.3 0.0 8.8e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 CP023447_00033 - 6e-07 29.2 0.0 8.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 CP023447_00033 - 2.7e-06 26.8 3.4 6.4e-06 25.6 0.3 2.3 1 1 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 CP023447_00033 - 3.6e-05 22.9 0.3 0.0019 17.2 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 CP023447_00033 - 3.9e-05 23.5 0.2 0.00012 21.9 0.2 1.8 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 CP023447_00033 - 0.0003 20.1 0.1 0.0007 19.0 0.1 1.6 1 0 0 1 1 1 1 VirC1 protein AAA_24 PF13479.6 CP023447_00033 - 0.00049 19.9 0.2 0.0011 18.7 0.1 1.7 1 1 1 2 2 2 1 AAA domain AAA_26 PF13500.6 CP023447_00033 - 0.00067 19.5 0.7 0.5 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 CP023447_00033 - 0.0024 17.1 0.4 0.13 11.4 0.1 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 CP023447_00033 - 0.0048 16.8 0.2 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 NTPase SRP54 PF00448.22 CP023447_00033 - 0.0073 16.0 1.4 0.015 14.9 0.1 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 CP023447_00033 - 0.06 13.2 0.8 6.1 6.7 0.3 2.7 1 1 1 2 2 2 0 Helicase AAA_18 PF13238.6 CP023447_00033 - 0.062 13.8 0.4 0.18 12.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CP023447_00033 - 0.083 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 CP023447_00033 - 0.12 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CP023447_00034 - 1.1e-42 145.9 0.1 1.8e-42 145.2 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CP023447_00034 - 0.00053 20.3 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CP023447_00034 - 0.00098 19.2 0.1 0.0037 17.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ResIII PF04851.15 CP023447_00034 - 0.0015 18.6 0.0 0.0015 18.6 0.0 2.7 1 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 CP023447_00034 - 0.0015 18.3 0.8 0.0044 16.8 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CP023447_00034 - 0.0021 17.7 0.1 0.0079 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CP023447_00034 - 0.0022 18.5 0.0 0.0022 18.5 0.0 2.6 2 1 0 2 2 1 1 ABC transporter cobW PF02492.19 CP023447_00034 - 0.0028 17.3 1.4 0.035 13.7 1.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 CP023447_00034 - 0.0031 17.5 0.9 0.023 14.6 0.0 2.6 2 2 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 CP023447_00034 - 0.0031 17.0 0.0 0.0079 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region CbiA PF01656.23 CP023447_00034 - 0.007 16.4 3.3 0.07 13.2 0.9 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 CP023447_00034 - 0.0072 16.8 0.9 0.032 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CP023447_00034 - 0.011 15.5 0.9 0.13 11.9 0.3 2.7 2 1 0 2 2 1 0 IstB-like ATP binding protein T2SSE PF00437.20 CP023447_00034 - 0.011 14.8 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 CP023447_00034 - 0.011 15.7 0.3 0.058 13.4 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CP023447_00034 - 0.012 15.5 0.7 0.038 13.9 0.1 2.2 2 1 1 3 3 2 0 RsgA GTPase AAA_16 PF13191.6 CP023447_00034 - 0.021 15.2 0.0 0.056 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain NB-ARC PF00931.22 CP023447_00034 - 0.021 14.0 0.0 0.052 12.7 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 CP023447_00034 - 0.026 15.0 13.2 0.42 11.1 0.3 2.6 2 1 0 2 2 2 0 AAA domain ParA PF10609.9 CP023447_00034 - 0.038 13.4 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 CP023447_00034 - 0.045 13.2 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Roc PF08477.13 CP023447_00034 - 0.045 14.0 0.6 1 9.6 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CP023447_00034 - 0.047 13.7 0.2 0.047 13.7 0.2 2.6 2 1 0 2 2 2 0 AAA domain VirE PF05272.11 CP023447_00034 - 0.049 13.4 0.1 0.22 11.2 0.0 2.2 3 0 0 3 3 2 0 Virulence-associated protein E NACHT PF05729.12 CP023447_00034 - 0.056 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 CP023447_00034 - 0.061 13.8 0.5 0.16 12.4 0.5 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CP023447_00034 - 0.062 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CP023447_00034 - 0.08 13.3 0.2 0.23 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CP023447_00034 - 0.097 13.2 0.1 0.38 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 CP023447_00034 - 0.12 12.1 1.4 0.28 10.9 0.3 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 CP023447_00034 - 0.14 11.5 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CP023447_00034 - 0.17 12.0 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3391 PF11871.8 CP023447_00034 - 0.25 11.9 1.7 0.55 10.8 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) NTPase_1 PF03266.15 CP023447_00034 - 0.52 10.2 3.4 4 7.3 0.5 2.4 1 1 0 2 2 2 0 NTPase HPPK PF01288.20 CP023447_00035 - 2e-20 73.4 0.0 2.3e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DHquinase_II PF01220.19 CP023447_00036 - 1e-57 193.7 0.3 1.2e-57 193.4 0.3 1.1 1 0 0 1 1 1 1 Dehydroquinase class II Enoyl_reductase PF12241.8 CP023447_00036 - 0.016 14.5 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region PCuAC PF04314.13 CP023447_00036 - 0.035 13.9 0.1 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Copper chaperone PCu(A)C Amidohydro_1 PF01979.20 CP023447_00037 - 5.3e-61 206.8 0.0 6.2e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CP023447_00037 - 1.3e-07 31.5 0.0 0.016 14.7 0.0 3.3 2 2 0 3 3 3 3 Amidohydrolase family Peptidase_S49 PF01343.18 CP023447_00038 - 6.8e-53 178.8 0.2 8.7e-53 178.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 CP023447_00038 - 5.5e-06 26.4 0.3 7e-05 22.8 0.3 2.2 1 1 0 1 1 1 1 Clp protease SDH_sah PF01972.16 CP023447_00038 - 0.00055 19.0 0.3 0.0009 18.3 0.1 1.5 1 1 0 1 1 1 1 Serine dehydrogenase proteinase Ligase_CoA PF00549.19 CP023447_00038 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 CoA-ligase CsgA PF17334.2 CP023447_00038 - 0.21 12.3 1.1 3.1 8.6 0.0 2.6 2 1 0 2 2 2 0 Minor curli fiber component A GSH-S_ATP PF02955.16 CP023447_00039 - 0.056 12.8 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF4821 PF16092.5 CP023447_00039 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Zn_ribbon_SprT PF17283.2 CP023447_00040 - 0.0036 17.2 1.1 0.0064 16.4 1.1 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Hemerythrin PF01814.23 CP023447_00041 - 4.9e-06 27.2 1.4 6.3e-06 26.8 1.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain LANC_like PF05147.13 CP023447_00041 - 0.022 13.3 0.1 0.028 13.0 0.1 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein RHH_7 PF16777.5 CP023447_00041 - 0.046 14.1 0.1 0.085 13.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG LUD_dom PF02589.15 CP023447_00042 - 1.3e-29 103.3 0.2 1.7e-29 102.9 0.2 1.2 1 0 0 1 1 1 1 LUD domain AAA_5 PF07728.14 CP023447_00042 - 0.068 13.2 0.1 0.19 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsX_ECD PF18075.1 CP023447_00042 - 0.26 11.9 3.8 2.1 9.0 0.5 2.6 2 1 1 3 3 3 0 FtsX extracellular domain LUD_dom PF02589.15 CP023447_00043 - 7.8e-52 175.8 0.2 1.3e-51 175.1 0.0 1.4 2 0 0 2 2 2 1 LUD domain DUF3390 PF11870.8 CP023447_00043 - 9.3e-17 61.2 0.0 1.9e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Fer4_8 PF13183.6 CP023447_00043 - 1.1e-11 44.9 1.5 3.1e-11 43.6 1.5 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 CP023447_00043 - 4.6e-09 36.7 2.0 1.1e-08 35.5 2.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CP023447_00043 - 1e-08 35.1 8.1 4.4e-08 33.1 7.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CP023447_00043 - 1.8e-08 33.9 11.7 0.00027 20.6 2.3 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CP023447_00043 - 5.7e-08 33.2 4.6 1.4e-07 32.0 4.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 CP023447_00043 - 1e-06 28.5 11.3 0.00029 20.8 1.8 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 CP023447_00043 - 4.8e-06 26.6 5.7 6e-05 23.1 6.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CP023447_00043 - 1.8e-05 24.6 11.2 0.018 15.1 1.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 CP023447_00043 - 4.7e-05 23.4 4.6 0.051 13.7 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_20 PF14691.6 CP023447_00043 - 0.00016 21.4 2.9 0.06 13.1 0.1 2.5 2 0 0 2 2 2 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_4 PF12800.7 CP023447_00043 - 0.00031 21.0 11.3 0.00053 20.3 1.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 CP023447_00043 - 0.0012 19.7 11.6 0.05 14.5 11.9 2.7 1 1 2 3 3 3 3 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 CP023447_00043 - 0.0022 18.8 5.7 1.1 10.1 1.0 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 CP023447_00043 - 0.0029 18.4 16.2 0.23 12.5 3.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 CP023447_00043 - 0.026 14.7 5.7 2 8.6 0.1 2.8 3 0 0 3 3 2 0 4Fe-4S dicluster domain Ribosomal_L5_C PF00673.21 CP023447_00043 - 0.043 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Fer4_13 PF13370.6 CP023447_00043 - 0.27 11.8 7.9 0.42 11.2 0.7 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I CCG PF02754.16 CP023447_00044 - 8.5e-31 106.0 0.4 2.7e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Cysteine-rich domain HTH_11 PF08279.12 CP023447_00044 - 0.029 14.3 0.1 7.3 6.6 0.0 2.7 2 0 0 2 2 2 0 HTH domain Lactate_perm PF02652.14 CP023447_00045 - 1.2e-205 684.2 48.6 1.4e-205 683.9 48.6 1.0 1 0 0 1 1 1 1 L-lactate permease CDtoxinA PF03498.14 CP023447_00046 - 1.1e-49 167.9 0.0 1.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain DUF2141 PF09912.9 CP023447_00046 - 0.069 13.1 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Exo_endo_phos PF03372.23 CP023447_00047 - 3.4e-18 66.0 0.2 4.9e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CP023447_00047 - 0.17 11.8 0.0 4.2 7.2 0.0 2.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase CDtoxinA PF03498.14 CP023447_00048 - 1e-45 155.0 0.1 1.4e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 CP023447_00048 - 1.4e-06 28.9 0.5 3.7e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CP023447_00048 - 1.6e-05 25.1 0.4 6.9e-05 23.1 0.4 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF4492 PF14899.6 CP023447_00049 - 1.7e-25 88.7 8.4 1.7e-25 88.7 8.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4492) Cyt_bd_oxida_I PF01654.17 CP023447_00050 - 1.6e-171 570.5 23.0 2.1e-171 570.2 23.0 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Oxidored_q5_N PF01059.17 CP023447_00050 - 1.9 8.6 15.0 9.3 6.4 0.8 4.4 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Cyt_bd_oxida_II PF02322.15 CP023447_00051 - 4.4e-74 249.6 31.0 5e-74 249.4 31.0 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II TrbL PF04610.14 CP023447_00051 - 0.002 17.9 11.8 0.002 17.9 11.8 3.9 2 2 2 4 4 4 1 TrbL/VirB6 plasmid conjugal transfer protein DUF334 PF03904.13 CP023447_00051 - 0.055 13.0 0.9 0.17 11.4 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF5362 PF17319.2 CP023447_00051 - 0.68 9.8 6.3 1.6 8.6 0.0 3.2 2 1 0 2 2 2 0 Family of unknown function (DUF5362) Asp_Glu_race PF01177.22 CP023447_00053 - 2e-56 191.4 2.4 2.3e-56 191.2 2.4 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 CP023447_00053 - 0.00035 20.0 0.4 0.0032 16.9 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase PA PF02225.22 CP023447_00053 - 0.022 14.7 0.0 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 PA domain AAA_33 PF13671.6 CP023447_00053 - 0.083 13.1 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain HTH_CodY PF08222.11 CP023447_00053 - 0.16 11.6 3.3 0.94 9.1 0.2 3.2 4 0 0 4 4 4 0 CodY helix-turn-helix domain UDG PF03167.19 CP023447_00054 - 1.1e-20 74.2 0.1 1.5e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Lyase_1 PF00206.20 CP023447_00055 - 8.3e-102 340.8 0.0 1e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CP023447_00055 - 4.3e-24 84.7 0.1 1.3e-23 83.1 0.1 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus SH3_17 PF18350.1 CP023447_00055 - 0.088 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain DcuA_DcuB PF03605.14 CP023447_00056 - 3.1e-134 447.5 28.5 3.9e-134 447.2 28.5 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter CitMHS PF03600.16 CP023447_00056 - 0.14 11.3 52.4 0.034 13.4 30.7 2.7 1 1 1 2 2 2 0 Citrate transporter Tmemb_18A PF09771.9 CP023447_00056 - 7 7.1 5.9 11 6.5 0.0 3.5 2 1 2 4 4 4 0 Transmembrane protein 188 TPR_2 PF07719.17 CP023447_00057 - 0.0002 21.2 7.6 0.21 11.8 0.3 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat HZS_alpha PF18582.1 CP023447_00057 - 0.0024 18.3 0.0 0.016 15.7 0.0 2.2 2 0 0 2 2 2 1 Hydrazine synthase alpha subunit middle domain TPR_6 PF13174.6 CP023447_00057 - 0.33 11.7 2.6 5.5 7.8 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CP023447_00057 - 1.5 9.2 4.2 7.7 7.0 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1425 PF07233.12 CP023447_00058 - 7.2e-08 32.2 0.0 8.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1425) LpoB PF13036.6 CP023447_00059 - 6.4e-45 152.7 0.1 8e-45 152.4 0.1 1.1 1 0 0 1 1 1 1 Peptidoglycan-synthase activator LpoB DUF3799 PF12684.7 CP023447_00059 - 0.12 12.1 0.0 0.46 10.2 0.0 1.8 1 1 1 2 2 2 0 PDDEXK-like domain of unknown function (DUF3799) CTP_synth_N PF06418.14 CP023447_00060 - 0.0094 15.3 1.9 0.4 10.0 0.3 2.3 2 0 0 2 2 2 2 CTP synthase N-terminus Rotamase_2 PF13145.6 CP023447_00060 - 0.13 13.1 0.4 0.13 13.1 0.4 3.0 3 1 0 3 3 3 0 PPIC-type PPIASE domain CsgG PF03783.14 CP023447_00061 - 1.9e-06 27.3 3.0 2.2e-06 27.1 1.0 2.0 2 0 0 2 2 2 1 Curli production assembly/transport component CsgG LPP20 PF02169.16 CP023447_00061 - 0.0011 19.3 6.6 0.0011 19.3 6.6 2.7 2 0 0 2 2 2 1 LPP20 lipoprotein AAA_assoc_2 PF16193.5 CP023447_00061 - 0.0058 16.9 0.2 0.26 11.6 0.1 2.7 2 0 0 2 2 2 1 AAA C-terminal domain CarbopepD_reg_2 PF13715.6 CP023447_00061 - 1.4 8.9 6.8 0.78 9.8 0.1 3.6 3 1 1 4 4 4 0 CarboxypepD_reg-like domain Ribosomal_L21p PF00829.21 CP023447_00062 - 1.1e-31 109.0 5.4 1.2e-31 108.9 5.4 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF5599 PF18141.1 CP023447_00062 - 0.028 14.6 0.1 0.043 14.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5599) Ribosomal_L27 PF01016.19 CP023447_00063 - 3.7e-38 129.4 5.0 4.1e-38 129.3 5.0 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein GTP1_OBG PF01018.22 CP023447_00064 - 1.1e-54 184.2 7.9 1.5e-54 183.8 7.9 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CP023447_00064 - 1.3e-21 76.8 0.0 2.1e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CP023447_00064 - 2.5e-09 36.9 0.0 5.1e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CP023447_00064 - 0.049 12.6 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AA_kinase PF00696.28 CP023447_00065 - 5.3e-37 127.7 0.6 6.1e-37 127.5 0.6 1.0 1 0 0 1 1 1 1 Amino acid kinase family Formyl_trans_N PF00551.19 CP023447_00066 - 3e-35 121.6 0.0 4.7e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CP023447_00066 - 5.1e-20 71.6 0.0 9.1e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain BPL_LplA_LipB PF03099.19 CP023447_00067 - 3.8e-13 49.5 0.0 5.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ubiquitin_4 PF18036.1 CP023447_00067 - 0.034 14.2 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_31 PF13614.6 CP023447_00068 - 1.3e-65 220.7 3.2 1.3e-65 220.7 3.2 1.5 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CP023447_00068 - 3.7e-26 91.7 0.2 5.2e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 CP023447_00068 - 2.2e-14 53.4 0.9 3.6e-13 49.4 0.5 2.3 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 CP023447_00068 - 1.6e-12 47.5 0.2 2e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 CP023447_00068 - 2e-10 40.6 0.0 3.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 CP023447_00068 - 3.8e-09 36.4 0.5 2.8e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 CP023447_00068 - 3.8e-08 32.9 0.3 1.2e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 CP023447_00068 - 6.2e-05 22.4 0.2 0.00018 20.9 0.1 1.7 1 1 0 1 1 1 1 VirC1 protein SRP54 PF00448.22 CP023447_00068 - 0.0032 17.1 1.2 0.018 14.7 0.2 2.1 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain DUF1027 PF06265.11 CP023447_00068 - 0.028 14.4 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) DUF1906 PF08924.11 CP023447_00068 - 0.051 13.7 0.0 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) AAA_24 PF13479.6 CP023447_00068 - 0.063 13.0 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 CP023447_00068 - 0.069 12.9 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 CP023447_00068 - 0.088 12.4 0.1 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CP023447_00068 - 0.088 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SecA_DEAD PF07517.14 CP023447_00068 - 0.25 10.6 1.7 4.8 6.4 0.2 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain ResIII PF04851.15 CP023447_00068 - 0.54 10.2 3.1 1.2 9.2 0.8 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ParBc PF02195.18 CP023447_00069 - 5.4e-26 90.7 0.6 3.6e-25 88.1 0.1 2.4 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_ParB PF17762.1 CP023447_00069 - 1.1e-14 54.0 0.6 1.1e-14 54.0 0.6 2.9 3 0 0 3 3 3 1 HTH domain found in ParB protein Raf1_N PF18578.1 CP023447_00069 - 0.13 12.8 0.4 23 5.5 0.0 3.0 3 1 0 3 3 3 0 Rubisco accumulation factor 1 alpha helical domain Popeye PF04831.13 CP023447_00069 - 0.13 12.4 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Popeye protein conserved region HTH_19 PF12844.7 CP023447_00069 - 0.14 12.2 5.4 14 5.8 0.1 4.3 3 1 0 4 4 4 0 Helix-turn-helix domain LAGLIDADG_WhiA PF14527.6 CP023447_00069 - 0.25 11.4 4.6 1.3 9.2 0.3 3.0 3 1 0 3 3 3 0 WhiA LAGLIDADG-like domain DUF365 PF04033.12 CP023447_00069 - 0.81 10.0 3.5 1.2 9.4 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF365) ATP-synt_B PF00430.18 CP023447_00070 - 2.3e-10 40.7 10.5 3.1e-10 40.3 10.5 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) PMT2_N PF17987.1 CP023447_00070 - 0.034 14.3 0.7 0.046 13.9 0.7 1.3 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal DUF948 PF06103.11 CP023447_00070 - 0.041 14.1 1.5 0.095 13.0 0.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PAGK PF15284.6 CP023447_00070 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor DUF5119 PF17145.4 CP023447_00070 - 0.067 13.1 0.1 0.08 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) Spc7 PF08317.11 CP023447_00070 - 0.11 11.4 14.5 0.12 11.2 14.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CSG2 PF16965.5 CP023447_00070 - 0.17 10.8 1.1 0.19 10.6 1.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator HTH_37 PF13744.6 CP023447_00070 - 0.19 11.7 6.6 0.27 11.2 2.6 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain Flg_hook PF02120.16 CP023447_00070 - 0.42 10.5 5.1 5.5 6.9 0.8 2.2 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK ERG2_Sigma1R PF04622.12 CP023447_00070 - 0.44 9.8 1.7 0.58 9.5 1.2 1.4 1 1 0 1 1 1 0 ERG2 and Sigma1 receptor like protein CemA PF03040.14 CP023447_00070 - 1.2 9.1 6.4 1.4 8.8 6.4 1.2 1 0 0 1 1 1 0 CemA family Macoilin PF09726.9 CP023447_00070 - 1.3 7.5 11.1 1.5 7.3 11.1 1.0 1 0 0 1 1 1 0 Macoilin family GrpE PF01025.19 CP023447_00070 - 6.9 6.3 14.4 1.5 8.4 2.6 2.1 1 1 1 2 2 2 0 GrpE ATP-synt_B PF00430.18 CP023447_00071 - 0.008 16.3 0.2 0.008 16.3 0.2 1.3 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 CP023447_00072 - 0.00022 21.6 2.8 0.00022 21.6 2.8 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Plasmid_parti PF01672.16 CP023447_00072 - 0.0019 18.8 0.8 0.0027 18.3 0.8 1.3 1 0 0 1 1 1 1 Putative plasmid partition protein ATP-synt_B PF00430.18 CP023447_00072 - 0.0036 17.4 3.6 0.0042 17.2 3.6 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DUF4954 PF16314.5 CP023447_00072 - 0.011 14.0 1.3 0.011 13.9 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Tweety PF04906.13 CP023447_00072 - 0.64 8.6 2.7 0.7 8.5 2.7 1.1 1 0 0 1 1 1 0 Tweety OSCP PF00213.18 CP023447_00073 - 3.3e-22 79.4 3.0 4.5e-22 79.0 3.0 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATP-synt_ab PF00006.25 CP023447_00074 - 1.4e-76 256.9 0.1 2.1e-76 256.3 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CP023447_00074 - 6.3e-51 172.0 0.6 1e-50 171.2 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CP023447_00074 - 3e-17 62.9 1.7 9.3e-17 61.3 1.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 CP023447_00074 - 2.2e-05 23.9 1.4 0.00013 21.4 0.3 2.6 2 0 0 2 2 2 1 KaiC Arginosuc_synth PF00764.19 CP023447_00074 - 0.046 13.0 0.2 0.082 12.2 0.2 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase HAS-barrel PF09378.10 CP023447_00074 - 0.061 13.5 0.1 0.25 11.5 0.1 2.1 2 1 0 2 2 2 0 HAS barrel domain Fe_dep_repress PF01325.19 CP023447_00074 - 0.074 13.3 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain ATP-synt PF00231.19 CP023447_00075 - 4.2e-83 279.3 12.2 4.7e-83 279.1 12.2 1.0 1 0 0 1 1 1 1 ATP synthase PTEN_C2 PF10409.9 CP023447_00075 - 0.11 12.3 0.8 0.22 11.3 0.8 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Snf7 PF03357.21 CP023447_00075 - 0.12 12.0 8.4 0.033 13.8 3.2 2.3 2 0 0 2 2 2 0 Snf7 BLOC1_2 PF10046.9 CP023447_00075 - 6.4 7.2 11.4 1.6 9.1 1.6 3.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP-synt_ab PF00006.25 CP023447_00076 - 6.6e-65 218.7 0.0 9.7e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CP023447_00076 - 1.2e-18 67.3 0.1 3.4e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 CP023447_00076 - 0.014 15.2 0.8 0.26 11.2 0.2 2.9 2 1 0 2 2 2 0 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 CP023447_00076 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 CP023447_00076 - 0.11 11.7 0.3 0.22 10.7 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 CP023447_00076 - 0.16 12.3 0.7 0.29 11.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain ATP-synt_DE_N PF02823.16 CP023447_00077 - 2.7e-24 84.9 0.2 3.3e-24 84.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain MotA_ExbB PF01618.16 CP023447_00078 - 3.1e-25 88.4 0.1 4e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 CP023447_00079 - 2.8e-28 98.7 2.3 3.2e-28 98.5 2.3 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_2 PF13103.6 CP023447_00080 - 1.5e-12 47.6 0.1 2.7e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 TonB C terminal SHE3 PF17078.5 CP023447_00080 - 0.0069 16.1 2.0 0.011 15.5 2.0 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 TRA-1_regulated PF02343.16 CP023447_00080 - 0.15 12.1 1.4 0.24 11.5 0.8 1.6 1 1 1 2 2 2 0 TRA-1 regulated protein R03H10.4 DUF3349 PF11829.8 CP023447_00080 - 0.36 11.6 2.2 0.56 11.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF948 PF06103.11 CP023447_00080 - 8.7 6.7 6.8 6.2 7.2 3.7 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pectate_lyase22 PF14583.6 CP023447_00081 - 1.9e-08 33.4 2.3 3.5e-07 29.2 0.3 2.7 1 1 2 3 3 3 1 Oligogalacturonate lyase PD40 PF07676.12 CP023447_00081 - 2.7e-06 27.1 1.2 0.3 11.1 0.2 3.8 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 CP023447_00081 - 0.00048 19.0 1.1 0.96 8.1 0.1 2.9 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region TolB_N PF04052.13 CP023447_00081 - 0.014 15.5 0.1 0.05 13.8 0.1 1.9 2 0 0 2 2 2 0 TolB amino-terminal domain MNE1 PF13762.6 CP023447_00081 - 0.017 15.1 0.6 0.15 12.0 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component Kelch_3 PF13415.6 CP023447_00081 - 0.25 11.7 4.5 17 5.9 0.0 3.9 4 1 0 4 4 4 0 Galactose oxidase, central domain NUMOD1 PF07453.13 CP023447_00081 - 0.72 10.2 4.4 1.5 9.2 0.7 3.3 2 1 1 3 3 3 0 NUMOD1 domain OmpA PF00691.20 CP023447_00082 - 7.2e-21 74.4 0.0 1.1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 OmpA family ApbE PF02424.15 CP023447_00082 - 0.028 14.0 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 ApbE family Pilus_CpaD PF09476.10 CP023447_00082 - 0.051 13.3 0.3 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) TPR_6 PF13174.6 CP023447_00083 - 5.6e-07 29.8 0.1 0.0029 18.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CP023447_00083 - 1.5e-05 24.8 0.1 0.00062 19.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CP023447_00083 - 0.00032 20.7 0.5 0.0013 18.8 0.5 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CP023447_00083 - 0.00034 20.3 0.7 0.0013 18.4 0.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CP023447_00083 - 0.0017 19.0 0.0 0.044 14.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Jnk-SapK_ap_N PF09744.9 CP023447_00083 - 0.0051 17.0 9.1 0.0051 17.0 9.1 2.2 1 1 2 3 3 3 1 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 CP023447_00083 - 0.0088 16.3 8.4 0.0088 16.3 8.4 2.7 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CorA PF01544.18 CP023447_00083 - 0.043 13.1 3.5 0.074 12.4 3.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_19 PF14559.6 CP023447_00083 - 0.043 14.3 0.1 0.22 12.1 0.0 2.3 3 0 0 3 3 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CP023447_00083 - 0.067 13.4 0.4 0.21 11.8 0.3 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CP023447_00083 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1664 PF07889.12 CP023447_00083 - 0.08 13.0 11.4 0.21 11.7 2.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 CP023447_00083 - 0.85 9.8 23.7 0.13 12.5 14.0 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4407 PF14362.6 CP023447_00083 - 1.4 8.2 10.9 2.2 7.6 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 CP023447_00083 - 1.4 8.2 12.8 0.062 12.6 4.3 2.0 2 0 0 2 2 2 0 FAM76 protein DUF4140 PF13600.6 CP023447_00083 - 1.9 9.0 11.3 12 6.4 0.1 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tweety PF04906.13 CP023447_00083 - 7.2 5.2 6.4 5 5.7 5.0 1.5 1 1 0 1 1 1 0 Tweety Golgin_A5 PF09787.9 CP023447_00083 - 8.1 5.8 18.9 35 3.7 18.6 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 FKBP_C PF00254.28 CP023447_00084 - 2.6e-06 27.7 0.1 5.3e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Acyl_transf_1 PF00698.21 CP023447_00085 - 6.3e-21 75.2 0.0 7.5e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 CP023447_00085 - 0.032 14.0 0.0 0.096 12.4 0.0 1.7 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis PNP_UDP_1 PF01048.20 CP023447_00086 - 4.3e-43 147.2 0.0 5e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily ATP_bind_3 PF01171.20 CP023447_00087 - 5.8e-22 78.3 0.0 8.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 CP023447_00087 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 CP023447_00087 - 0.029 14.0 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase Isochorismatase PF00857.20 CP023447_00088 - 9.1e-14 52.0 0.0 1e-13 51.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family rpo132 PF12415.8 CP023447_00088 - 0.14 11.5 0.1 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Poxvirus DNA dependent RNA polymerase RecO_N_2 PF13114.6 CP023447_00089 - 2e-32 110.7 0.1 5.6e-32 109.3 0.0 1.8 2 0 0 2 2 2 1 RecO N terminal Mad3_BUB1_I PF08311.12 CP023447_00089 - 0.021 14.8 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 RecO_N PF11967.8 CP023447_00089 - 0.022 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal UPF0054 PF02130.17 CP023447_00090 - 2.7e-34 117.8 1.0 3.1e-34 117.5 1.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PIG-S PF10510.9 CP023447_00090 - 0.036 12.9 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF573 PF04504.14 CP023447_00091 - 0.021 15.5 8.4 0.051 14.2 4.7 2.9 1 1 1 3 3 3 0 Protein of unknown function, DUF573 GNAT_acetyltr_2 PF13718.6 CP023447_00091 - 0.18 11.2 3.2 0.17 11.2 1.4 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase 2 Dus PF01207.17 CP023447_00092 - 6.2e-76 255.5 0.0 7.6e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TIM PF00121.18 CP023447_00092 - 0.00027 20.4 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Triosephosphate isomerase TMP-TENI PF02581.17 CP023447_00092 - 0.0067 15.8 0.1 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 Thiamine monophosphate synthase PdxJ PF03740.13 CP023447_00092 - 0.0093 15.1 0.4 0.52 9.4 0.0 2.5 2 1 1 3 3 3 1 Pyridoxal phosphate biosynthesis protein PdxJ BtpA PF03437.15 CP023447_00092 - 0.056 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 BtpA family EAP30 PF04157.16 CP023447_00092 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_48 PF17906.1 CP023447_00092 - 0.18 12.0 0.5 76 3.5 0.0 3.9 4 0 0 4 4 4 0 HTH domain in Mos1 transposase DUF910 PF06014.11 CP023447_00093 - 0.0037 17.3 2.3 1.9 8.5 0.1 2.8 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF910) Utp13 PF08625.11 CP023447_00093 - 0.012 15.6 4.3 0.016 15.1 0.4 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF325 PF03804.13 CP023447_00093 - 0.076 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Viral proteins of unknown function zf-dskA_traR PF01258.17 CP023447_00094 - 1.3e-11 44.2 2.3 2.1e-11 43.6 2.3 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Fib_alpha PF08702.10 CP023447_00094 - 0.1 12.8 3.6 0.77 9.9 0.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1289 PF06945.13 CP023447_00094 - 0.11 12.3 4.4 0.75 9.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) SPOUT_MTase PF02590.17 CP023447_00095 - 7.4e-40 136.4 0.5 8.3e-40 136.3 0.5 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase BBP1_C PF15272.6 CP023447_00095 - 0.001 19.0 1.1 0.0016 18.3 1.1 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Carboxyl_trans PF01039.22 CP023447_00096 - 1.4e-21 76.8 0.2 3.2e-21 75.5 0.2 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 CP023447_00096 - 1.1e-07 31.7 9.0 1.9e-07 31.0 9.0 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain RNA_POL_M_15KD PF02150.16 CP023447_00096 - 0.071 13.0 1.7 0.45 10.4 1.8 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Inositol_P PF00459.25 CP023447_00097 - 1.3e-14 54.4 0.0 1.9e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 CP023447_00097 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Bac_surface_Ag PF01103.23 CP023447_00098 - 4.4e-68 230.2 10.5 7.3e-68 229.4 10.5 1.4 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 CP023447_00098 - 2e-39 134.0 36.8 8e-13 48.8 3.4 5.7 6 0 0 6 6 6 5 Surface antigen variable number repeat POTRA_2 PF08479.11 CP023447_00098 - 9e-06 25.4 2.6 0.61 10.0 0.1 5.3 5 0 0 5 5 5 2 POTRA domain, ShlB-type POTRA_1 PF08478.10 CP023447_00098 - 3.7e-05 23.9 4.5 0.59 10.5 0.1 4.4 4 0 0 4 4 4 2 POTRA domain, FtsQ-type ShlB PF03865.13 CP023447_00098 - 0.00035 20.1 1.4 0.00057 19.4 0.2 1.9 2 0 0 2 2 2 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB PDH PF02153.17 CP023447_00099 - 2.6e-69 233.1 0.2 2.9e-69 233.0 0.2 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CP023447_00099 - 0.00016 22.2 0.2 0.00063 20.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CP023447_00099 - 0.00044 20.5 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IPT PF01745.16 CP023447_00099 - 0.03 13.7 0.2 0.05 13.0 0.2 1.3 1 0 0 1 1 1 0 Isopentenyl transferase FNIP PF05725.12 CP023447_00099 - 0.048 13.8 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 FNIP Repeat IlvN PF07991.12 CP023447_00099 - 0.072 12.7 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF4411 PF14367.6 CP023447_00099 - 0.13 12.2 0.9 0.21 11.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) Semialdhyde_dh PF01118.24 CP023447_00099 - 0.15 12.5 0.2 0.46 10.9 0.1 2.0 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M23 PF01551.22 CP023447_00100 - 1.3e-17 63.7 2.8 1.7e-17 63.4 0.3 2.3 3 0 0 3 3 3 1 Peptidase family M23 Sigma_reg_N PF13800.6 CP023447_00100 - 0.089 13.1 0.9 0.78 10.1 0.7 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Big_3_2 PF12245.8 CP023447_00100 - 0.15 12.3 0.7 3.5 7.9 0.1 2.6 2 1 0 2 2 2 0 Bacterial Ig-like domain LpxC PF03331.13 CP023447_00101 - 2.8e-101 338.6 0.0 3.2e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Peptidase_M22 PF00814.25 CP023447_00102 - 0.00024 20.9 0.0 0.0003 20.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family GHMP_kinases_N PF00288.26 CP023447_00103 - 7.8e-10 38.9 0.0 2.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CP023447_00103 - 0.00048 20.4 0.0 0.0018 18.6 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal zf-FPG_IleRS PF06827.14 CP023447_00104 - 0.045 13.6 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS IF-2 PF11987.8 CP023447_00105 - 3.2e-37 126.8 1.1 3.2e-37 126.8 1.1 2.6 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 CP023447_00105 - 1.7e-33 115.8 2.5 1.7e-33 115.8 2.5 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 CP023447_00105 - 6.6e-32 109.1 6.2 3.2e-15 55.7 0.3 3.4 3 0 0 3 3 3 2 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 CP023447_00105 - 1.6e-11 44.3 0.2 1.6e-11 44.3 0.2 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP023447_00105 - 1.2e-09 38.4 10.1 1.7e-06 28.3 1.4 3.5 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Ras PF00071.22 CP023447_00105 - 1.5e-06 27.9 0.0 1.5e-06 27.9 0.0 2.5 3 0 0 3 3 3 1 Ras family Arf PF00025.21 CP023447_00105 - 4.8e-06 26.1 1.7 1.8e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 ADP-ribosylation factor family FeoB_N PF02421.18 CP023447_00105 - 0.00017 21.2 0.2 0.00096 18.7 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CP023447_00105 - 0.00028 20.9 7.5 0.0023 17.8 0.0 3.6 3 1 1 4 4 4 2 RsgA GTPase Roc PF08477.13 CP023447_00105 - 0.0016 18.6 0.0 0.0044 17.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 CP023447_00105 - 0.056 13.5 1.6 0.87 9.6 0.0 3.4 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain RBFA PF02033.18 CP023447_00106 - 1.7e-13 50.9 0.0 1.9e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Ribosome-binding factor A CAAP1 PF15335.6 CP023447_00106 - 0.027 15.0 0.5 0.13 12.9 0.3 2.2 1 1 1 2 2 2 0 Caspase activity and apoptosis inhibitor 1 PRANC PF09372.10 CP023447_00106 - 0.079 13.3 0.5 0.89 9.9 0.0 2.2 1 1 0 2 2 2 0 PRANC domain DUF150 PF02576.17 CP023447_00107 - 3.4e-25 88.2 0.4 1.7e-24 86.0 0.1 1.9 2 0 0 2 2 2 1 RimP N-terminal domain DUF150_C PF17384.2 CP023447_00107 - 2.4e-18 66.0 2.9 3.5e-18 65.5 2.9 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain LolA_like PF17131.4 CP023447_00107 - 0.02 14.6 0.6 0.034 13.9 0.6 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein LSM14 PF12701.7 CP023447_00107 - 0.036 14.2 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain AAA_5 PF07728.14 CP023447_00108 - 3.8e-12 46.4 0.0 5.9e-10 39.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CP023447_00108 - 3e-05 24.4 0.0 0.11 13.0 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CP023447_00108 - 0.049 14.0 0.1 0.71 10.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain CHASE5 PF17149.4 CP023447_00108 - 0.076 12.9 0.7 1.9 8.4 0.1 2.9 2 0 0 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins DUF2330 PF10092.9 CP023447_00108 - 0.3 10.1 1.7 0.65 9.0 1.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) AAA_11 PF13086.6 CP023447_00108 - 4.5 7.0 5.3 9.3 5.9 0.1 3.1 2 2 1 3 3 3 0 AAA domain McrBC PF10117.9 CP023447_00109 - 1.9e-108 362.4 13.0 2.4e-108 362.1 13.0 1.1 1 0 0 1 1 1 1 McrBC 5-methylcytosine restriction system component ABC-3 PF00950.17 CP023447_00110 - 6.2e-72 242.2 35.7 7e-72 242.0 35.7 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 CP023447_00110 - 4.2e-10 39.1 35.4 7.4e-10 38.3 35.4 1.4 1 1 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 CP023447_00111 - 1.3e-28 100.2 0.1 3.5e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CP023447_00111 - 3.4e-09 37.0 0.7 0.00028 20.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CP023447_00111 - 4.9e-07 29.4 1.0 0.002 17.6 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CP023447_00111 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CP023447_00111 - 0.00034 20.9 0.1 0.0014 18.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CP023447_00111 - 0.00057 19.9 1.5 0.0057 16.6 1.5 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_15 PF13175.6 CP023447_00111 - 0.0027 17.5 14.7 0.0081 15.9 14.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 CP023447_00111 - 0.0049 16.5 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 CP023447_00111 - 0.0056 16.9 0.1 0.13 12.6 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CP023447_00111 - 0.011 15.5 0.0 0.099 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP023447_00111 - 0.013 16.0 6.6 0.076 13.5 6.6 2.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CP023447_00111 - 0.027 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 CP023447_00111 - 0.027 14.8 0.0 0.043 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CP023447_00111 - 0.033 14.6 0.3 0.13 12.7 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CP023447_00111 - 0.043 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 CP023447_00111 - 0.044 13.8 0.2 0.2 11.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CP023447_00111 - 0.062 13.0 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 CP023447_00111 - 0.084 12.8 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 CP023447_00111 - 0.12 12.5 0.1 0.3 11.2 0.0 1.8 2 1 1 3 3 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CP023447_00111 - 0.15 12.2 0.1 0.54 10.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain ZnuA PF01297.17 CP023447_00112 - 1.5e-55 188.4 3.1 1.8e-55 188.1 3.1 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic NMT1_3 PF16868.5 CP023447_00112 - 0.12 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family W2 PF02020.18 CP023544_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP023544_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 CP023544_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP023544_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 CP023544_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 CP023544_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP023544_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP023544_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP023544_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP023544_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP023544_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP023544_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 CP023544_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP023544_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP023544_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP023544_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP023544_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 CP023544_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP023544_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 CP023544_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP023544_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP023544_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP023544_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP023544_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 CP023544_00008 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 CP023544_00008 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 CP023544_00009 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP023544_00009 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP023544_00009 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP023544_00009 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP023544_00009 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 CP023544_00010 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 CP023544_00010 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 CP023544_00010 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 CP023544_00011 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP023544_00011 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 CP023544_00011 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 CP023544_00011 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 CP023544_00011 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 CP023544_00011 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 CP023544_00012 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 CP023544_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 CP023544_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP023544_00014 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 CP023544_00014 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 CP023544_00014 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP023544_00014 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE TcdA_TcdB PF12919.7 CP023544_00015 - 0.00084 18.7 3.1 0.00093 18.6 3.1 1.0 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Bcl-2 PF00452.19 CP023544_00015 - 0.16 12.6 0.3 0.77 10.5 0.1 1.8 1 1 1 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family ESP PF16590.5 CP023544_00015 - 0.55 10.5 4.8 0.27 11.5 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 CP023544_00015 - 6.5 6.9 13.7 0.42 10.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function Toprim_3 PF13362.6 CP023544_00018 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP023544_00018 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP023544_00018 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP023544_00018 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 CP023544_00019 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 CP023544_00019 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 CP023544_00020 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 CP023544_00020 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 CP023544_00020 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 CP023544_00022 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 CP023544_00023 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 CP023544_00024 - 1.1e-14 54.5 0.0 2.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP023544_00024 - 0.00029 20.3 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP023544_00024 - 0.0018 18.0 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP023544_00024 - 0.0084 15.5 0.0 0.053 12.9 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP023544_00024 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP023544_00024 - 0.15 12.1 1.7 0.77 9.8 1.7 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP023544_00024 - 0.38 10.7 3.0 4.7 7.2 0.0 3.6 3 1 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) VASP_tetra PF08776.11 CP023544_00024 - 2.7 7.6 6.7 4.7 6.9 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 CP023544_00025 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP023544_00025 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 CP023544_00025 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 CP023544_00026 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 CP023544_00028 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP023544_00028 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 CP023544_00029 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP023544_00029 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 CP023544_00030 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 CP023544_00030 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 CP023544_00030 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 CP023544_00031 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 CP023544_00032 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 CP023544_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP023544_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP023544_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP023544_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 CP023544_00034 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP023544_00034 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 CP023544_00034 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 CP023544_00034 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 CP023544_00035 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP023544_00035 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 CP023544_00035 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 CP023544_00035 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 CP023544_00036 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 CP023544_00037 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP023544_00037 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 CP023544_00038 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 CP023544_00039 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP023544_00039 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 CP023544_00040 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP023544_00040 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP023544_00040 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP023544_00040 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP023544_00040 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP023544_00040 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CP023544_00040 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CP023544_00040 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP023544_00040 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP023544_00040 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP023544_00040 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP023544_00040 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 CP023544_00040 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CP023544_00040 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 CP023544_00040 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 CP023544_00040 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CP023544_00040 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CP023544_00040 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 CP023544_00040 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 CP023544_00040 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CP023544_00040 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 CP023544_00040 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP023544_00040 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP023544_00040 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP023544_00040 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP023544_00040 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP023544_00040 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP023544_00040 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CP023544_00040 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CP023544_00040 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP023544_00040 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP023544_00040 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 CP023544_00041 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 CP023544_00042 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP023544_00042 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP023544_00042 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 CP023544_00042 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 CP023544_00042 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 CP023544_00043 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP023544_00043 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 CP023544_00044 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 CP023544_00045 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 CP023544_00045 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 CP023544_00046 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 CP023544_00046 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 CP023544_00046 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 CP023544_00047 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 CP023544_00048 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP023544_00048 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP023544_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP023544_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP023544_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP023544_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP023544_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP023544_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP023544_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP023544_00048 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP023544_00048 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP023544_00048 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP023544_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP023544_00048 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP023544_00048 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP023544_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP023544_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 CP023544_00050 - 2.9e-05 24.0 2.2 2.9e-05 24.0 2.2 1.6 2 0 0 2 2 2 1 PcfJ-like protein Intein_splicing PF14890.6 CP023544_00050 - 0.0053 16.7 3.0 0.015 15.3 3.0 1.9 1 1 0 1 1 1 1 Intein splicing domain APH PF01636.23 CP023544_00052 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CP023544_00052 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 CP023544_00052 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CP023544_00052 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 CP023544_00052 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 CP023544_00053 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP023544_00053 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP023544_00053 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP023544_00053 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP023544_00053 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP023544_00053 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP023544_00053 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP023544_00053 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP023544_00053 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 CP023544_00055 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 CP023544_00055 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 CP023544_00055 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 CP023544_00055 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 CP023544_00055 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 CP023544_00056 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 CP023544_00057 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 CP023544_00057 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 CP023544_00057 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 CP023544_00057 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 CP023544_00058 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 CP023544_00059 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CP023544_00059 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CP023544_00059 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CP023544_00059 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 CP023544_00059 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CP023544_00059 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CP023544_00059 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CP023544_00059 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CP023544_00059 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CP023544_00059 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CP023544_00059 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CP023544_00059 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CP023544_00059 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 CP023544_00059 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 CP023544_00059 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 CP023544_00059 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 CP023544_00059 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP023544_00059 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 CP023544_00059 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 CP023544_00059 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CP023544_00059 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 CP023544_00059 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 CP023544_00059 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CP023544_00059 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 CP023544_00059 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 CP023544_00059 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 CP023544_00059 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 CP023544_00059 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 CP023544_00059 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 CP023544_00059 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 CP023544_00059 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CP023544_00059 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 CP023544_00059 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CP023544_00059 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 CP023544_00059 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 CP023544_00059 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 CP023544_00059 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 CP023544_00060 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP023544_00060 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CP023544_00060 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 CP023544_00060 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 CP023544_00060 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 CP023544_00060 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 CP023544_00061 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 CP023544_00062 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 CP023544_00063 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CP023544_00063 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CP023544_00063 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CP023544_00063 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CP023544_00063 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CP023544_00063 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CP023544_00063 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CP023544_00063 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 CP023544_00064 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CP023544_00064 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CP023544_00064 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 CP023544_00065 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 CP023544_00065 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 CP023544_00065 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 CP023544_00066 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 CP023544_00066 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 CP023544_00066 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Resolvase PF00239.21 CP023546_00001 - 3e-12 46.9 0.0 4.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 CP023546_00001 - 0.011 15.5 0.1 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_25 PF13481.6 CP023546_00002 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CP023546_00002 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CP023546_00002 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CP023546_00002 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 CP023546_00002 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CP023546_00002 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 CP023546_00002 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 CP023546_00003 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 CP023546_00004 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 CP023546_00006 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 CP023546_00006 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 CP023546_00006 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 CP023546_00007 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 CP023546_00007 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 CP023546_00008 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 CP023546_00008 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 CP023546_00008 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 CP023546_00008 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Sds3 PF08598.11 CP023546_00011 - 0.041 13.9 5.7 0.048 13.7 5.7 1.2 1 0 0 1 1 1 0 Sds3-like ESP PF16590.5 CP023546_00011 - 0.48 10.7 5.3 0.26 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 CP023546_00011 - 4.2 7.5 13.8 0.42 10.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function HTH_46 PF15977.5 CP023546_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 CP023546_00012 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 CP023546_00012 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 CP023546_00012 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 CP023546_00012 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 CP023546_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF3913 PF13052.6 CP023546_00014 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Acetyltransf_7 PF13508.7 CP023546_00015 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CP023546_00015 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 CP023546_00015 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 CP023546_00015 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 CP023546_00015 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 CP023546_00015 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 NYN PF01936.18 CP023546_00016 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 CP023546_00016 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 CP023546_00016 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) SNF2_N PF00176.23 CP023546_00017 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 CP023546_00017 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CP023546_00017 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CP023546_00017 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 CP023546_00017 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 CP023546_00018 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 CP023546_00018 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 CP023546_00019 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 CP023546_00019 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 CP023546_00019 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 CP023546_00019 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 CP023546_00019 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 CP023546_00020 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 CP023546_00020 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 CP023546_00021 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 CP023546_00021 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 CP023546_00021 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 CP023546_00021 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 CP023546_00021 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 CP023546_00022 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 CP023546_00022 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 CP023546_00022 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 CP023546_00022 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 CP023546_00022 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 CP023546_00022 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 CP023546_00022 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 CP023546_00023 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 CP023546_00024 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 CP023546_00024 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 CP023546_00025 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 CP023546_00025 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Sigma70_r4_2 PF08281.12 CP023546_00026 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 CP023546_00026 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 CP023546_00026 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain zf-HC2 PF13490.6 CP023546_00027 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 CP023546_00027 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 CP023546_00027 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain APH PF01636.23 CP023546_00028 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CP023546_00028 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CP023546_00028 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Acetyltransf_1 PF00583.25 CP023546_00029 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CP023546_00029 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CP023546_00029 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CP023546_00029 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CP023546_00029 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CP023546_00029 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CP023546_00029 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CP023546_00029 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Adenyl_transf PF04439.12 CP023546_00030 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Peptidase_C15 PF01470.17 CP023546_00031 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 CP023546_00032 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CP023546_00032 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 CP023546_00032 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 CP023546_00032 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 CP023546_00032 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 CP023546_00032 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_18 PF13238.6 CP023546_00033 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CP023546_00033 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CP023546_00033 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CP023546_00033 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 CP023546_00033 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CP023546_00033 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CP023546_00033 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CP023546_00033 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CP023546_00033 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CP023546_00033 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CP023546_00033 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CP023546_00033 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CP023546_00033 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 CP023546_00033 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 CP023546_00033 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 CP023546_00033 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 CP023546_00033 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CP023546_00033 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 CP023546_00033 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 CP023546_00033 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CP023546_00033 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 CP023546_00033 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 CP023546_00033 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CP023546_00033 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 CP023546_00033 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 CP023546_00033 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 CP023546_00033 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 CP023546_00033 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 CP023546_00033 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 CP023546_00033 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 CP023546_00033 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CP023546_00033 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 CP023546_00033 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CP023546_00033 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 CP023546_00033 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 CP023546_00033 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 CP023546_00033 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family DUF4111 PF13427.6 CP023546_00034 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) DUF4111 PF13427.6 CP023546_00035 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 CP023546_00035 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 CP023546_00035 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 CP023546_00035 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain PNP_UDP_1 PF01048.20 CP023546_00036 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily CPSF_A PF03178.15 CP023546_00037 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 CP023546_00037 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 CP023546_00037 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 CP023546_00037 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 CP023546_00037 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) GTP_EFTU PF00009.27 CP023546_00039 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CP023546_00039 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CP023546_00039 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CP023546_00039 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CP023546_00039 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CP023546_00039 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CP023546_00039 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 CP023546_00039 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CP023546_00039 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 CP023546_00040 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CP023546_00040 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 CP023546_00040 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CP023546_00040 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 CP023546_00040 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase PcfJ PF14284.6 CP023546_00042 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 CP023546_00042 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 CP023546_00043 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CP023546_00043 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 CP023546_00043 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 CP023546_00043 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 CP023546_00043 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CP023546_00043 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 CP023546_00043 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 CP023546_00043 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CP023546_00043 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 CP023546_00043 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 CP023546_00043 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 CP023546_00043 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 CP023546_00043 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CP023546_00043 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 CP023546_00043 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 CP023546_00043 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 CP023546_00043 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1461 PF07314.11 CP023546_00044 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CdhD PF03599.16 CP023546_00045 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 CP023546_00045 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 CP023546_00045 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 CP023546_00046 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 CP023546_00046 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TrbM PF07424.11 CP023546_00047 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 CP023546_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 CP023546_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) T4SS-DNA_transf PF02534.14 CP023546_00049 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 CP023546_00049 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 CP023546_00049 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 CP023546_00049 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 CP023546_00049 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Carbam_trans_N PF02543.15 CP023546_00050 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T2SSE PF00437.20 CP023546_00051 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CP023546_00051 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CP023546_00051 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CP023546_00051 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CP023546_00051 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CP023546_00051 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CP023546_00051 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CP023546_00051 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 CP023546_00051 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 CP023546_00051 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 CP023546_00051 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 CP023546_00051 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 CP023546_00051 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CP023546_00051 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 CP023546_00051 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 CP023546_00051 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CP023546_00051 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CP023546_00051 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 CP023546_00051 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 CP023546_00051 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CP023546_00051 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 CP023546_00051 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 CP023546_00051 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 CP023546_00051 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 CP023546_00051 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CP023546_00051 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 CP023546_00051 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 CP023546_00051 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CP023546_00051 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CP023546_00051 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CP023546_00051 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CP023546_00051 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 CP023546_00052 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 CP023546_00052 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 CP023546_00053 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein VirB8 PF04335.13 CP023546_00054 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 CP023546_00054 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C La_HTH_kDCL PF18177.1 CP023546_00055 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain TrbL PF04610.14 CP023546_00056 - 2.8e-30 105.7 32.6 2.8e-30 105.7 32.6 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 CP023546_00056 - 0.072 12.9 0.7 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 CP023546_00056 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 CP023546_00056 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 CP023546_00057 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 CP023546_00057 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 CP023546_00057 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 CP023546_00057 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 CP023546_00058 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 CP023546_00058 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 CP023546_00058 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 CP023546_00058 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 CP023546_00059 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 CP023546_00060 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 CP023546_00061 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 CP023546_00061 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 CP023546_00061 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 CP023546_00062 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 CP023546_00062 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 CP023546_00063 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 CP023546_00063 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 CP023546_00065 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Relaxase PF03432.14 KC907204_00001 - 2.1e-09 37.3 4.9 2.1e-09 37.3 4.9 2.9 2 1 1 3 3 3 1 Relaxase/Mobilisation nuclease domain B3 PF02362.21 KC907204_00001 - 0.00093 19.0 0.2 0.01 15.7 0.1 2.6 2 0 0 2 2 2 1 B3 DNA binding domain Ig_GlcNase PF18368.1 KC907204_00001 - 0.039 14.1 0.2 0.17 12.0 0.0 2.1 3 0 0 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain DUF2884 PF11101.8 KC907204_00001 - 0.045 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Lip_prot_lig_C PF10437.9 KX686749_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 KX686749_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 KX686749_00003 - 0.01 15.2 2.9 0.01 15.2 2.9 2.3 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 KX686749_00003 - 0.78 8.8 4.5 0.88 8.6 4.5 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LysE PF01810.18 KX686749_00004 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 KX686749_00004 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 KX686749_00004 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 KX686749_00004 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 KX686749_00004 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 KX686749_00004 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 KX686749_00004 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 KX686749_00004 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 KX686749_00004 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 KX686749_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 KX686749_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 KX686749_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 KX686749_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 KX686749_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 KX686749_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 KX686749_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 KX686749_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 KX686749_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 KX686749_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 KX686749_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 KX686749_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 KX686749_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 KX686749_00009 - 1.4e-16 60.2 0.7 4.2e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 KX686749_00009 - 8.6e-08 32.4 8.6 8.6e-08 32.4 8.6 4.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KX686749_00009 - 9.2e-07 29.2 0.2 4.9e-05 23.6 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Eco57I PF07669.11 KX686749_00009 - 2.1e-05 24.9 0.7 0.00022 21.7 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase DEAD PF00270.29 KX686749_00009 - 2.5e-05 24.1 2.4 0.0015 18.3 0.5 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase HTH_19 PF12844.7 KX686749_00010 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 KX686749_00010 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 KX686749_00010 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 KX686749_00010 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KX686749_00010 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 KX686749_00010 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 KX686749_00010 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 KX686749_00010 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 KX686749_00010 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 KX686749_00010 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 KX686749_00010 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KX686749_00010 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 KX686749_00010 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 KX686749_00010 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Relaxase PF03432.14 KX686749_00011 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 KX686749_00012 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 KX686749_00012 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 KX686749_00012 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 KX686749_00012 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 KX686749_00012 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain CdvA PF18822.1 KX686749_00013 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 KX686749_00013 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 KX686749_00013 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 KX686749_00015 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 KX686749_00015 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 KX686749_00015 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 KX686749_00015 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 KX686749_00016 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 KX686749_00016 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 KX686749_00017 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 KX686749_00017 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 KX686749_00017 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 KX686749_00019 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 KX686749_00020 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 KX686749_00021 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KX686749_00021 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 KX686749_00021 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 KX686749_00021 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 KX686749_00021 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KX686749_00021 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 KX686749_00021 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 KX686749_00022 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 KX686749_00022 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 KX686749_00022 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 KX686749_00023 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 KX686749_00025 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 KX686749_00025 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 KX686749_00026 - 7e-51 173.3 0.4 1.6e-50 172.1 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 KX686749_00026 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 KX686749_00027 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 KX686749_00027 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 KX686749_00027 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 KX686749_00028 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 KX686749_00029 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 KX686749_00030 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 KX686749_00030 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 KX686749_00030 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 KX686749_00030 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 KX686749_00031 - 1.8e-28 100.3 13.3 2.5e-28 99.9 13.3 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 KX686749_00031 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 KX686749_00031 - 0.017 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 KX686749_00031 - 0.5 11.1 11.4 0.41 11.3 4.5 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 KX686749_00032 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 KX686749_00032 - 0.065 13.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 KX686749_00032 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Trep_dent_lipo PF09710.10 KX686749_00033 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 KX686749_00033 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 KX686749_00033 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 KX686749_00034 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 KX686749_00034 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 KX686749_00035 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 KX686749_00035 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 KX686749_00035 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 KX686749_00036 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 KX686749_00036 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 KX686749_00037 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KX686749_00037 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 KX686749_00037 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 KX686749_00037 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KX686749_00037 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KX686749_00037 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 KX686749_00037 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KX686749_00037 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 KX686749_00037 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 KX686749_00037 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 KX686749_00037 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 KX686749_00037 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 KX686749_00037 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 KX686749_00037 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KX686749_00037 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KX686749_00037 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 KX686749_00037 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KX686749_00037 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 KX686749_00037 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 KX686749_00037 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KX686749_00037 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KX686749_00037 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 KX686749_00037 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 KX686749_00037 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 KX686749_00037 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 KX686749_00037 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 KX686749_00037 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 KX686749_00037 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 KX686749_00037 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KX686749_00037 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KX686749_00037 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 KX686749_00038 - 8.4e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 KX686749_00038 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 KX686749_00038 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 KX686749_00038 - 0.19 11.8 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 KX686749_00039 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 KX686749_00039 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 KX686749_00040 - 3.9e-38 130.8 2.1 5e-38 130.5 2.1 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 KX686749_00040 - 0.17 10.9 0.1 1 8.4 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal PRELI PF04707.14 KX686749_00041 - 0.024 14.4 1.8 0.032 14.0 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 KX686749_00041 - 1.7 8.4 10.4 3.2 7.5 8.6 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT20 PF14931.6 KX686749_00041 - 3.6 7.8 9.8 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CdhD PF03599.16 KX686749_00042 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 KX686749_00042 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 KX686749_00042 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 KX686749_00043 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 KX686749_00044 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KX686749_00044 - 1.8e-12 47.4 0.5 9.7e-12 45.0 0.1 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 KX686749_00044 - 1.6e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 KX686749_00044 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 KX686749_00044 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KX686749_00044 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KX686749_00044 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KX686749_00044 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 KX686749_00044 - 0.088 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 KX686749_00044 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 KX686749_00044 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 KX686749_00044 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 KX686749_00044 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 KX686749_00044 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 KX686749_00044 - 6.9 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 KX686749_00044 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 KX686749_00045 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 KX686749_00045 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 KX686749_00047 - 2.9e-58 196.6 0.3 4.1e-58 196.1 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KX686749_00047 - 2.6e-23 82.1 0.0 9.7e-23 80.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KX686749_00047 - 1.1e-16 60.6 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KX686749_00047 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KX686749_00047 - 1e-06 28.8 0.1 2.4e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KX686749_00047 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KX686749_00047 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 KX686749_00047 - 0.021 14.1 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 KX686749_00047 - 0.045 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPT PF07931.12 KX686749_00048 - 9.2e-06 25.6 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KX686749_00048 - 1.2e-05 25.9 0.0 1.6e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KX686749_00048 - 0.019 15.1 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MKT1_N PF12247.8 KX686749_00048 - 0.041 14.2 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication APH PF01636.23 KX686749_00049 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KX686749_00049 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 KX686749_00049 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 KX686749_00049 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 KX686749_00049 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 KX686749_00049 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 KX686749_00050 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 KX686749_00051 - 1.1e-35 123.2 0.1 1.3e-35 122.9 0.1 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Zeta_toxin PF06414.12 KX686749_00051 - 3.2e-06 26.6 0.0 3.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KX686749_00051 - 3.4e-06 27.4 0.0 3.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KX686749_00051 - 1.6e-05 25.3 0.0 2.4e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KX686749_00051 - 2.2e-05 24.7 0.0 3.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KX686749_00051 - 3.3e-05 24.4 0.0 3.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KX686749_00051 - 9.9e-05 22.5 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KX686749_00051 - 0.00015 22.2 0.0 0.00019 21.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KX686749_00051 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KX686749_00051 - 0.0011 18.7 0.0 0.0012 18.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KX686749_00051 - 0.0014 19.0 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KX686749_00051 - 0.0015 18.6 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KX686749_00051 - 0.0015 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 KX686749_00051 - 0.0015 19.1 0.0 0.0021 18.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 KX686749_00051 - 0.002 17.8 0.2 0.0027 17.5 0.2 1.2 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KX686749_00051 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 KX686749_00051 - 0.0032 17.4 0.1 0.005 16.8 0.1 1.4 1 1 0 1 1 1 1 NTPase ATPase PF06745.13 KX686749_00051 - 0.0062 15.9 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 KX686749_00051 - 0.0079 15.3 0.0 0.0094 15.0 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KX686749_00051 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KX686749_00051 - 0.019 15.3 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KX686749_00051 - 0.021 14.7 0.1 0.053 13.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Hydin_ADK PF17213.3 KX686749_00051 - 0.026 14.8 0.2 0.036 14.4 0.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Viral_helicase1 PF01443.18 KX686749_00051 - 0.03 14.1 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KX686749_00051 - 0.032 14.0 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CPT PF07931.12 KX686749_00051 - 0.032 14.1 0.0 0.047 13.5 0.0 1.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 KX686749_00051 - 0.034 13.7 0.1 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KX686749_00051 - 0.035 13.3 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KX686749_00051 - 0.036 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 KX686749_00051 - 0.039 13.3 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 KX686749_00051 - 0.047 13.2 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KX686749_00051 - 0.048 13.6 0.0 0.051 13.5 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KX686749_00051 - 0.053 13.0 0.4 0.12 11.9 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 KX686749_00051 - 0.054 13.4 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 KX686749_00051 - 0.066 13.6 0.0 0.099 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KX686749_00051 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 KX686749_00051 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP-synt_ab PF00006.25 KX686749_00051 - 0.11 12.2 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 KX686749_00051 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase IPT PF01745.16 KX686749_00051 - 0.14 11.5 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Isopentenyl transferase AAA_3 PF07726.11 KX686749_00051 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 KX686749_00051 - 0.16 10.6 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 KX686749_00051 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ArsA_ATPase PF02374.15 KX686749_00051 - 0.17 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase cobW PF02492.19 KX686749_00051 - 0.18 11.4 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APH PF01636.23 KX686749_00052 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KX686749_00052 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KX686749_00052 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Radical_SAM PF04055.21 KX686749_00053 - 1.3e-14 55.0 0.0 2.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KX686749_00053 - 4.9e-05 23.4 0.0 0.00037 20.6 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KX686749_00053 - 0.048 13.9 0.2 0.098 12.9 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain APH PF01636.23 KX931103_00001 - 1.9e-24 86.9 0.0 2.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KX931103_00001 - 0.0013 18.3 1.5 0.0013 18.3 1.5 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KX931104_00001 - 1.9e-24 86.9 0.0 2.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KX931104_00001 - 0.0013 18.3 1.5 0.0013 18.3 1.5 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase LysE PF01810.18 MLDY01000008_00001 - 5.6e-05 22.7 0.0 6.7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 MLDY01000008_00001 - 0.002 18.3 0.3 0.0021 18.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) TerC PF03741.16 MLDY01000008_00001 - 0.041 13.6 0.3 0.047 13.4 0.3 1.0 1 0 0 1 1 1 0 Integral membrane protein TerC family DUF5305 PF17231.2 MLDY01000008_00001 - 0.077 12.4 0.6 0.1 12.0 0.2 1.4 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Saf_2TM PF18303.1 MLDY01000008_00001 - 0.11 12.1 0.8 0.13 11.8 0.3 1.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain PetL PF05115.14 MLDY01000008_00001 - 3.4 7.7 9.7 4 7.5 1.2 2.5 2 1 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Flp1_like PF16982.5 MLDY01000008_00002 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 MLDY01000008_00002 - 0.26 10.8 3.9 0.28 10.7 3.5 1.3 1 1 0 1 1 1 0 Negative regulator of p53/TP53 YopX PF09643.10 MLDY01000008_00004 - 1.9e-14 53.8 7.2 4.7e-13 49.3 7.2 2.2 1 1 0 1 1 1 1 YopX protein RE_ApaLI PF09499.10 MLDY01000008_00004 - 0.0081 15.9 0.6 0.0083 15.9 0.6 1.2 1 0 0 1 1 1 1 ApaLI-like restriction endonuclease DUF2583 PF10762.9 MLDY01000008_00006 - 0.67 10.4 3.8 15 6.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Topoisom_bac PF01131.20 MLDY01000008_00009 - 3.9e-97 325.9 7.9 5.4e-97 325.4 7.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 MLDY01000008_00009 - 1.9e-12 47.3 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 MLDY01000008_00009 - 1.6e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 MLDY01000008_00009 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 MLDY01000008_00009 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 MLDY01000008_00009 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 MLDY01000008_00009 - 0.055 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 MLDY01000008_00009 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 MLDY01000008_00009 - 0.089 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 MLDY01000008_00009 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 MLDY01000008_00009 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 MLDY01000008_00009 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 MLDY01000008_00009 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 MLDY01000008_00009 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 MLDY01000008_00009 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 MLDY01000008_00009 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 MLDY01000008_00010 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 MLDY01000008_00012 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 MLDY01000008_00012 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 MLDY01000008_00012 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 MLDY01000008_00013 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 MLDY01000008_00014 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 MLDY01000008_00014 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 MLDY01000008_00014 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 MLDY01000008_00014 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 MLDY01000008_00015 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 MLDY01000008_00015 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 MLDY01000008_00015 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 MLDY01000008_00015 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 MLDY01000008_00016 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 MLDY01000008_00016 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 MLDY01000008_00016 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 MLDY01000008_00016 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 MLDY01000008_00016 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 MLDY01000008_00016 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 MLDY01000008_00016 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 MLDY01000008_00016 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 MLDY01000008_00016 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 MLDY01000008_00016 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 MLDY01000008_00016 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 MLDY01000008_00016 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 MLDY01000008_00016 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 MLDY01000008_00016 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 MLDY01000008_00016 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 MLDY01000008_00016 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 MLDY01000008_00016 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 MLDY01000008_00016 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 MLDY01000008_00016 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 MLDY01000008_00016 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 MLDY01000008_00016 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 MLDY01000008_00016 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 MLDY01000008_00016 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 MLDY01000008_00016 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 MLDY01000008_00016 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 MLDY01000008_00016 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 MLDY01000008_00016 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 MLDY01000008_00016 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 MLDY01000008_00016 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 MLDY01000008_00016 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 MLDY01000008_00016 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 MLDY01000008_00017 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 MLDY01000008_00017 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 MLDY01000008_00018 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 MLDY01000008_00018 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 MLDY01000008_00019 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 MLDY01000008_00019 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 MLDY01000008_00020 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 MLDY01000008_00020 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 MLDY01000008_00021 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 MLDY01000008_00021 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 MLDY01000008_00021 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 MLDY01000008_00022 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 MLDY01000008_00022 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 MLDY01000008_00022 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 MLDY01000008_00022 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 MLDY01000008_00022 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 MLDY01000008_00022 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 MLDY01000008_00022 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 MLDY01000008_00022 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 MLDY01000008_00023 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 MLDY01000008_00023 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 MLDY01000008_00023 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 MLDY01000008_00023 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 MLDY01000008_00024 - 1.5e-25 89.2 0.1 1.8e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 MLDY01000008_00025 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 MLDY01000008_00026 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 MLDY01000008_00026 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 MLDY01000008_00026 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 MLDY01000008_00026 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 MLDY01000008_00026 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 MLDY01000008_00027 - 4.1e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 MLDY01000008_00027 - 7.7e-21 74.1 0.9 1.4e-20 73.3 0.9 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 MLDY01000008_00027 - 2.9e-07 29.8 0.9 6.6e-07 28.6 0.9 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 MLDY01000008_00027 - 0.013 15.6 3.4 1.5 8.8 0.0 3.7 4 1 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 MLDY01000008_00028 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 MLDY01000008_00028 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 MLDY01000008_00030 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Resolvase PF00239.21 MLDY01000008_00031 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 MLDY01000008_00031 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 MLDY01000008_00031 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_25 PF13481.6 MLDY01000008_00032 - 5.4e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 MLDY01000008_00032 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 MLDY01000008_00032 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 MLDY01000008_00032 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 MLDY01000008_00032 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 MLDY01000008_00032 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 MLDY01000008_00032 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 MLDY01000008_00033 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 MLDY01000008_00034 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 MLDY01000008_00036 - 0.0052 16.8 2.6 0.0069 16.4 2.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 MLDY01000008_00036 - 0.56 10.1 4.1 2 8.4 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 MLDY01000008_00037 - 0.027 14.4 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 MLDY01000008_00037 - 0.045 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 MLDY01000008_00037 - 0.068 13.6 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF4223 PF13978.6 MLDY01000008_00038 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) Toprim_3 PF13362.6 MLDY01000008_00039 - 2.1e-08 34.4 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 MLDY01000008_00039 - 0.14 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 MLDY01000008_00039 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2004 PF09406.10 MLDY01000008_00040 - 0.12 12.7 3.0 0.62 10.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) Sds3 PF08598.11 MLDY01000008_00042 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 MLDY01000008_00042 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 MLDY01000008_00042 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 MLDY01000008_00043 - 0.00011 22.1 5.7 0.067 13.2 0.7 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 MLDY01000008_00043 - 0.058 13.5 1.9 0.087 12.9 1.4 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DndE PF08870.11 MLDY01000008_00043 - 0.31 11.3 5.7 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 MLDY01000008_00043 - 0.53 10.6 5.9 2.5 8.5 2.0 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 MLDY01000008_00043 - 2 8.5 7.9 1 9.4 0.3 3.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Relaxase PF03432.14 MLDY01000008_00044 - 4.3e-09 36.3 8.2 4.3e-09 36.3 8.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF2768 PF10966.8 MLDY01000008_00045 - 0.053 14.0 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SNF2_N PF00176.23 MLDY01000008_00046 - 3e-16 59.1 1.8 5.1e-16 58.3 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 MLDY01000008_00046 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 MLDY01000008_00046 - 9.6e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 MLDY01000008_00046 - 8.1e-06 25.7 2.5 0.0012 18.7 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 MLDY01000008_00046 - 2.6e-05 24.7 0.7 0.00023 21.6 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 MLDY01000008_00047 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 MLDY01000008_00047 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 MLDY01000008_00048 - 5.3e-05 23.2 0.6 0.001 19.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 MLDY01000008_00048 - 0.0012 18.9 0.5 0.0079 16.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Mur_ligase_C PF02875.21 MLDY01000008_00048 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 MLDY01000008_00048 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 MLDY01000008_00049 - 0.00028 21.0 1.6 0.00035 20.7 1.6 1.4 1 0 0 1 1 1 1 T-antigen specific domain CEBP_ZZ PF16366.5 MLDY01000008_00049 - 0.022 15.0 2.6 0.03 14.6 2.6 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1272 PF06906.11 MLDY01000008_00049 - 0.049 13.7 3.8 0.074 13.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Lip_prot_lig_C PF10437.9 MLDZ01000009_00001 - 0.048 13.6 3.7 0.12 12.4 3.0 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus EptA_B_N PF08019.12 MLDZ01000009_00003 - 0.12 12.3 10.8 0.053 13.4 1.6 2.3 1 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB FeoB_associated PF12669.7 MLDZ01000009_00003 - 1.9 9.0 0.0 1.9 9.0 0.0 3.0 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DUF2070 PF09843.9 MLDZ01000009_00003 - 7.9 4.6 18.3 9.6 4.4 18.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Topoisom_bac PF01131.20 MLDZ01000009_00006 - 5.8e-97 325.3 7.7 8e-97 324.8 7.7 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 MLDZ01000009_00006 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 MLDZ01000009_00006 - 1.4e-08 34.4 14.8 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 MLDZ01000009_00006 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 MLDZ01000009_00006 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 MLDZ01000009_00006 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 MLDZ01000009_00006 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 MLDZ01000009_00006 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 MLDZ01000009_00006 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 MLDZ01000009_00006 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain FLYWCH PF04500.16 MLDZ01000009_00006 - 0.14 12.3 3.1 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain HTH_34 PF13601.6 MLDZ01000009_00006 - 0.47 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 MLDZ01000009_00006 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 MLDZ01000009_00006 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 MLDZ01000009_00006 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 MLDZ01000009_00006 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 MLDZ01000009_00006 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 MLDZ01000009_00007 - 0.055 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 MLDZ01000009_00008 - 0.039 13.8 0.5 0.039 13.8 0.5 1.8 2 0 0 2 2 2 0 PRELI-like family DUF2304 PF10066.9 MLDZ01000009_00008 - 0.1 12.8 0.9 0.24 11.6 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Rsd_AlgQ PF04353.13 MLDZ01000009_00008 - 1.3 8.9 6.1 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 MLDZ01000009_00009 - 2.6e-35 121.7 1.4 3.6e-35 121.2 1.4 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 MLDZ01000009_00010 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 MLDZ01000009_00010 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 MLDZ01000009_00010 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 MLDZ01000009_00011 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 MLDZ01000009_00011 - 9.9e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 MLDZ01000009_00011 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 MLDZ01000009_00011 - 0.046 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 MLDZ01000009_00012 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 MLDZ01000009_00012 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 MLDZ01000009_00012 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 MLDZ01000009_00012 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 MLDZ01000009_00012 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 MLDZ01000009_00012 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 MLDZ01000009_00012 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 MLDZ01000009_00012 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 MLDZ01000009_00012 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 MLDZ01000009_00012 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 MLDZ01000009_00012 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 MLDZ01000009_00012 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 MLDZ01000009_00012 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 MLDZ01000009_00012 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 MLDZ01000009_00012 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 MLDZ01000009_00012 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 MLDZ01000009_00012 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 MLDZ01000009_00012 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 MLDZ01000009_00012 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 MLDZ01000009_00012 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 MLDZ01000009_00012 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 MLDZ01000009_00012 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 MLDZ01000009_00012 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 MLDZ01000009_00012 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 MLDZ01000009_00012 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 MLDZ01000009_00012 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 MLDZ01000009_00012 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 MLDZ01000009_00012 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 MLDZ01000009_00012 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 MLDZ01000009_00012 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 MLDZ01000009_00012 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 MLDZ01000009_00013 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 MLDZ01000009_00013 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 MLDZ01000009_00014 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 MLDZ01000009_00014 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 MLDZ01000009_00015 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 MLDZ01000009_00015 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 MLDZ01000009_00016 - 0.035 13.0 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 MLDZ01000009_00016 - 1.5 8.6 5.2 2.6 7.9 5.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 MLDZ01000009_00017 - 8.7e-31 107.4 31.2 8.7e-31 107.4 31.2 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T4SS PF07996.11 MLDZ01000009_00018 - 2.2e-28 100.0 14.0 2.9e-28 99.6 14.0 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 MLDZ01000009_00018 - 0.0037 17.4 0.4 0.015 15.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 MLDZ01000009_00018 - 0.0089 16.7 5.2 0.0089 16.7 5.2 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 MLDZ01000009_00018 - 0.064 12.8 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 MLDZ01000009_00018 - 0.07 13.8 0.9 0.07 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain DHR10 PF18595.1 MLDZ01000009_00018 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 MLDZ01000009_00018 - 5.8 7.2 12.9 1.7 8.9 0.3 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 IF2_N PF04760.15 MLDZ01000009_00019 - 6.5e-05 22.7 5.8 0.00049 19.9 2.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HTH_16 PF12645.7 MLDZ01000009_00019 - 0.013 15.5 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 MLDZ01000009_00019 - 0.029 15.1 0.5 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor FliG_N PF14842.6 MLDZ01000009_00019 - 0.039 14.5 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain SSB PF00436.25 MLDZ01000009_00020 - 1.4e-25 89.3 0.1 1.8e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 MLDZ01000009_00021 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 MLDZ01000009_00022 - 6.9e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 MLDZ01000009_00022 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 MLDZ01000009_00022 - 0.031 13.9 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 MLDZ01000009_00022 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 MLDZ01000009_00022 - 0.56 10.3 5.4 7.7 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 MLDZ01000009_00023 - 3.6e-49 167.7 0.3 9e-49 166.4 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 MLDZ01000009_00023 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 MLDZ01000009_00023 - 3.8e-07 29.4 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 MLDZ01000009_00023 - 0.024 14.7 4.5 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 MLDZ01000009_00024 - 1.2e-15 57.5 7.6 1.4e-15 57.3 7.6 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 MLDZ01000009_00024 - 0.047 13.5 4.0 0.054 13.3 3.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 MLDZ01000009_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 MLDZ01000009_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 MLDZ01000009_00027 - 3.6e-33 114.7 0.7 4.5e-33 114.4 0.7 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 MLDZ01000009_00027 - 0.027 14.2 1.2 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 MLDZ01000009_00027 - 0.047 13.7 5.4 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 MLDZ01000009_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 MLDZ01000009_00028 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 MLDZ01000009_00028 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 MLDZ01000009_00028 - 0.0021 17.8 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 MLDZ01000009_00028 - 0.0072 15.7 0.0 0.058 12.7 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 MLDZ01000009_00028 - 0.013 15.9 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 MLDZ01000009_00028 - 0.2 11.7 2.0 0.95 9.5 2.0 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 MLDZ01000009_00028 - 0.35 10.8 3.5 5.1 7.1 0.0 3.8 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) VASP_tetra PF08776.11 MLDZ01000009_00028 - 3.8 7.2 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicA_toxin PF07927.12 MLDZ01000009_00029 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 MLDZ01000009_00030 - 4.2e-08 33.3 0.0 4.4e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 MLDZ01000009_00032 - 0.0043 17.1 1.7 0.0054 16.8 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 MLDZ01000009_00032 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 MLDZ01000009_00033 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 MLDZ01000009_00033 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 MLDZ01000009_00034 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 MLDZ01000009_00034 - 0.017 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein Sds3 PF08598.11 MLDZ01000009_00036 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 MLDZ01000009_00036 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 MLDZ01000009_00036 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 MLDZ01000009_00037 - 0.00012 22.0 7.0 0.043 13.8 1.2 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 MLDZ01000009_00037 - 0.063 13.4 2.6 0.071 13.2 1.5 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 MLDZ01000009_00037 - 0.47 10.8 6.1 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 MLDZ01000009_00037 - 0.53 10.4 9.0 1.5 8.9 0.4 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 MLDZ01000009_00037 - 0.57 10.5 7.1 0.61 10.4 1.8 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 MLDZ01000009_00038 - 7.8e-10 38.8 7.7 7.8e-10 38.8 7.7 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain YqaJ PF09588.10 MLDZ01000009_00038 - 0.03 14.5 3.9 0.24 11.6 0.4 3.0 2 1 1 3 3 3 0 YqaJ-like viral recombinase domain HTH_19 PF12844.7 MLDZ01000009_00039 - 6.3e-06 26.1 0.3 0.024 14.6 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 MLDZ01000009_00039 - 7.6e-06 25.9 0.0 6.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 MLDZ01000009_00039 - 0.00035 20.6 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 MLDZ01000009_00039 - 0.0024 17.4 0.1 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 MLDZ01000009_00039 - 0.0043 16.9 0.1 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_17 PF12728.7 MLDZ01000009_00039 - 0.028 14.6 0.0 0.4 10.9 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 MLDZ01000009_00039 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 MLDZ01000009_00039 - 0.046 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_26 PF13443.6 MLDZ01000009_00039 - 0.048 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Mga PF08280.11 MLDZ01000009_00039 - 0.049 13.7 2.0 1.7 8.7 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 MLDZ01000009_00039 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 MLDZ01000009_00039 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 MLDZ01000009_00039 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Crp PF00325.20 MLDZ01000009_00039 - 0.17 11.6 0.1 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family SNF2_N PF00176.23 MLDZ01000009_00040 - 2.3e-16 59.4 3.1 2.9e-16 59.2 0.3 2.5 3 1 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 MLDZ01000009_00040 - 3.2e-08 33.8 8.8 3.2e-08 33.8 8.8 4.1 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 MLDZ01000009_00040 - 6.8e-07 29.6 1.6 2.4e-05 24.6 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 MLDZ01000009_00040 - 9.8e-07 28.7 1.9 0.00054 19.8 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase BST2 PF16716.5 MLDZ01000009_00040 - 4.3 8.0 7.3 8.1 7.1 2.7 3.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Eco57I PF07669.11 MLDZ01000009_00041 - 1.2e-05 25.7 0.3 5e-05 23.8 0.3 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 MLDZ01000009_00041 - 0.004 16.7 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 MLDZ01000009_00042 - 8.5e-07 29.3 0.8 9.4e-07 29.1 0.8 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 MLDZ01000009_00043 - 7.8e-05 22.7 0.5 0.0011 19.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 MLDZ01000009_00043 - 0.00097 19.2 0.8 0.0077 16.3 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 MLDZ01000009_00043 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 MLDZ01000009_00043 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 MLDZ01000009_00044 - 0.02 15.0 7.2 0.03 14.5 7.2 1.4 1 1 0 1 1 1 0 T-antigen specific domain DUF1272 PF06906.11 MLDZ01000009_00044 - 0.059 13.5 6.2 0.095 12.8 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CEBP_ZZ PF16366.5 MLDZ01000009_00044 - 0.14 12.4 6.2 0.19 12.0 6.2 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain LIM PF00412.22 MLDZ01000009_00044 - 0.23 11.7 8.9 0.4 10.9 8.9 1.4 1 0 0 1 1 1 0 LIM domain DUF5595 PF18077.1 MLDZ01000009_00044 - 0.9 9.7 5.1 0.19 11.9 1.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) LysE PF01810.18 MLDZ01000009_00045 - 5.1e-06 26.1 0.0 5.8e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 MLDZ01000009_00045 - 0.00027 21.1 1.1 0.00031 20.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) Ac76 PF05814.11 MLDZ01000009_00045 - 0.0043 17.0 2.2 0.0049 16.8 2.2 1.1 1 0 0 1 1 1 1 Orf76 (Ac76) Saf_2TM PF18303.1 MLDZ01000009_00045 - 0.24 11.0 3.5 0.12 12.0 0.7 1.7 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF2873 PF11395.8 MLDZ01000009_00045 - 3.7 7.5 6.8 0.78 9.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2873) LPAM_1 PF08139.12 MLDZ01000009_00045 - 7.1 7.3 5.9 1.1 9.9 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Flp1_like PF16982.5 MLDZ01000009_00046 - 0.044 13.2 3.1 0.044 13.2 3.1 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 MLDZ01000009_00046 - 0.053 13.0 1.6 0.06 12.9 1.6 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 GTP_EFTU PF00009.27 MUJW01000047_00001 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 MUJW01000047_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 MUJW01000047_00001 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 MUJW01000047_00001 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 MUJW01000047_00001 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 MUJW01000047_00001 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 MUJW01000047_00001 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 MUJW01000047_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 MUJW01000047_00001 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 MUJW01000047_00002 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 MUJW01000047_00002 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 MUJW01000047_00002 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 MUJW01000047_00003 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 MUJW01000047_00004 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 MUJW01000047_00004 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 MUJW01000047_00005 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 MUJW01000047_00005 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 MUJW01000047_00005 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 MUJW01000047_00005 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 MUJW01000047_00005 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 MUJW01000047_00005 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 MUJW01000047_00005 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 MUJW01000047_00005 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 MUJW01000047_00005 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 MUJW01000047_00006 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 MUJW01000047_00006 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 MUJW01000047_00006 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 MUJW01000047_00006 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 MUJW01000047_00006 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 MUJW01000047_00007 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 MUJW01000047_00007 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 MUJW01000047_00008 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 MUJW01000047_00008 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 MUJW01000047_00008 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 MUJW01000047_00008 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 MUJW01000047_00008 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 MUJW01000047_00009 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 MUJW01000047_00010 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 MUJW01000047_00010 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 MUJW01000047_00010 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 MUJW01000047_00010 - 8.9e-06 25.6 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 MUJW01000047_00010 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 MUJW01000047_00011 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 MUJW01000047_00011 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 MUJW01000047_00011 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 MUJW01000047_00012 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 MUJW01000047_00012 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 MUJW01000047_00012 - 0.0083 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 MUJW01000047_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 MUJW01000047_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 MUJW01000047_00014 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 MUJW01000047_00014 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 MUJW01000047_00014 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 MUJW01000047_00014 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 MUJW01000047_00015 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 MUJW01000047_00015 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 MUJW01000047_00015 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 MUJW01000047_00017 - 0.19 11.7 5.6 0.39 10.7 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 MUJW01000047_00018 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 MUJW01000047_00018 - 0.074 13.0 0.3 0.33 10.9 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 MUJW01000047_00018 - 0.13 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 MUJW01000047_00018 - 0.27 11.9 5.3 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 MUJW01000047_00019 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 MUJW01000047_00019 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain UBA_6 PF18039.1 MUJW01000047_00020 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 MUJW01000047_00020 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 MUJW01000047_00020 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 MUJW01000047_00020 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 MUJW01000047_00021 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 MUJW01000047_00021 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 MUJW01000047_00021 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 MUJW01000047_00023 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system AAA_25 PF13481.6 MUJW01000047_00024 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 MUJW01000047_00024 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 MUJW01000047_00024 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 MUJW01000047_00024 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 MUJW01000047_00024 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 MUJW01000047_00024 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 MUJW01000047_00024 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 MUJW01000047_00025 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 MUJW01000047_00025 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 MUJW01000047_00025 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 MUJW01000047_00025 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 MUJW01000047_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 MUJW01000047_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 MUJW01000047_00028 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 MUJW01000047_00028 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 MUJW01000047_00029 - 2.6e-50 171.4 0.6 5.9e-50 170.2 0.6 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 MUJW01000047_00029 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 MUJW01000047_00029 - 0.046 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 MUJW01000047_00030 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 MUJW01000047_00030 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 MUJW01000047_00030 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 MUJW01000047_00030 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 MUJW01000047_00030 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3251 PF11622.8 MUJW01000047_00031 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 MUJW01000047_00031 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 MUJW01000047_00031 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 MUJW01000047_00031 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 MUJW01000047_00031 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 MUJW01000047_00031 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 MUJW01000047_00032 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 MUJW01000047_00033 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 MUJW01000047_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 MUJW01000047_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 MUJW01000047_00033 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 MUJW01000047_00034 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 MUJW01000047_00034 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 MUJW01000047_00034 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 MUJW01000047_00034 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 MUJW01000047_00034 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 MUJW01000047_00034 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 MUJW01000047_00034 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 MUJW01000047_00034 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 MUJW01000047_00035 - 3.6e-30 105.4 29.1 3.6e-30 105.4 29.1 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 MUJW01000047_00035 - 0.12 12.2 1.4 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 MUJW01000047_00035 - 1.3 10.0 5.2 2.2 9.3 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 MerC PF03203.14 MUJW01000047_00035 - 4.9 7.6 19.7 25 5.4 19.7 2.1 1 1 0 1 1 1 0 MerC mercury resistance protein Trep_dent_lipo PF09710.10 MUJW01000047_00036 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 MUJW01000047_00036 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 MUJW01000047_00037 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 MUJW01000047_00037 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 MUJW01000047_00038 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 MUJW01000047_00038 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 MUJW01000047_00039 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 MUJW01000047_00039 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 MUJW01000047_00040 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 MUJW01000047_00040 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 MUJW01000047_00040 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 MUJW01000047_00040 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 MUJW01000047_00040 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 MUJW01000047_00040 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 MUJW01000047_00040 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 MUJW01000047_00040 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 MUJW01000047_00040 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 MUJW01000047_00040 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 MUJW01000047_00040 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 MUJW01000047_00040 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 MUJW01000047_00040 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 MUJW01000047_00040 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 MUJW01000047_00040 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 MUJW01000047_00040 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 MUJW01000047_00040 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 MUJW01000047_00040 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 MUJW01000047_00040 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 MUJW01000047_00040 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 MUJW01000047_00040 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 MUJW01000047_00040 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 MUJW01000047_00040 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 MUJW01000047_00040 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 MUJW01000047_00040 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 MUJW01000047_00040 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 MUJW01000047_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 MUJW01000047_00040 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 MUJW01000047_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 MUJW01000047_00040 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 MUJW01000047_00040 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 MUJW01000047_00041 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 MUJW01000047_00041 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 MUJW01000047_00041 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 MUJW01000047_00041 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Phage_holin_3_6 PF07332.11 MUJW01000047_00041 - 0.22 11.6 0.2 0.35 10.9 0.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 MUJW01000047_00042 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 MUJW01000047_00042 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 MUJW01000047_00042 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 MUJW01000047_00042 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 MUJW01000047_00043 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 MUJW01000047_00044 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 MUJW01000047_00044 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 MUJW01000047_00044 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 MUJW01000047_00046 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 MUJW01000047_00047 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 MUJW01000047_00047 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 MUJW01000047_00047 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 MUJW01000047_00047 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 MUJW01000047_00047 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 MUJW01000047_00047 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 MUJW01000047_00047 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 MUJW01000047_00047 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 MUJW01000047_00047 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 MUJW01000047_00047 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 MUJW01000047_00047 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 MUJW01000047_00047 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 MUJW01000047_00047 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 MUJW01000047_00047 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 MUJW01000047_00047 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 MUJW01000047_00047 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 MUJW01000047_00047 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 MUJW01000047_00048 - 5.3e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 MUJW01000047_00048 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 MUJW01000047_00050 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 MUJW01000047_00050 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 MUJW01000047_00050 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 MUJW01000047_00050 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 MUJW01000047_00050 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 MUJW01000047_00050 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 MUJW01000047_00050 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 MUJW01000047_00050 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 MUJW01000047_00050 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Mur_ligase_M PF08245.12 NAAE01000001_00001 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 NAAE01000001_00001 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF4570 PF15134.6 NAAE01000001_00002 - 0.17 11.9 1.7 0.32 11.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) CTP_transf_3 PF02348.19 NAAE01000001_00003 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 NAAE01000001_00003 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 NAAE01000001_00003 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain PALP PF00291.25 NAAE01000001_00004 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 NAAE01000001_00004 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 NAAE01000001_00004 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain LpxK PF02606.14 NAAE01000001_00005 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 NAAE01000001_00005 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_synthase PF02540.17 NAAE01000001_00006 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 NAAE01000001_00006 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 NAAE01000001_00006 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 NAAE01000001_00006 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 NAAE01000001_00006 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 NAAE01000001_00006 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Lactamase_B PF00753.27 NAAE01000001_00007 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 NAAE01000001_00007 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1129 PF06570.11 NAAE01000001_00008 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) adh_short_C2 PF13561.6 NAAE01000001_00009 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 NAAE01000001_00009 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 NAAE01000001_00009 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 NAAE01000001_00009 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DHDPS PF00701.22 NAAE01000001_00010 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 NAAE01000001_00010 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Peptidase_M16_C PF05193.21 NAAE01000001_00011 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 NAAE01000001_00011 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 NAAE01000001_00011 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHO_dh PF01180.21 NAAE01000001_00012 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 NAAE01000001_00012 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 NAAE01000001_00012 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family ABC_membrane PF00664.23 NAAE01000001_00013 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 NAAE01000001_00013 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 NAAE01000001_00013 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 NAAE01000001_00013 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 NAAE01000001_00013 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 NAAE01000001_00013 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 NAAE01000001_00013 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 NAAE01000001_00013 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 NAAE01000001_00013 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 NAAE01000001_00013 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 NAAE01000001_00013 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_1e PF01406.19 NAAE01000001_00014 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 NAAE01000001_00014 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 NAAE01000001_00014 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 NAAE01000001_00014 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 NAAE01000001_00014 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 NAAE01000001_00014 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 NAAE01000001_00014 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) MurJ PF03023.14 NAAE01000001_00015 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 NAAE01000001_00015 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 FapA PF03961.13 NAAE01000001_00016 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 NAAE01000001_00016 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 NAAE01000001_00016 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 NAAE01000001_00016 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HHH_5 PF14520.6 NAAE01000001_00017 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 NAAE01000001_00017 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 NAAE01000001_00017 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 NAAE01000001_00017 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 NAAE01000001_00017 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 NAAE01000001_00017 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 NAAE01000001_00017 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 NAAE01000001_00017 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 NAAE01000001_00017 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 NAAE01000001_00017 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 NAAE01000001_00017 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 NAAE01000001_00017 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Dala_Dala_lig_C PF07478.13 NAAE01000001_00018 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 NAAE01000001_00018 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 NAAE01000001_00018 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 NAAE01000001_00018 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 NAAE01000001_00018 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 NAAE01000001_00018 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PhdYeFM_antitox PF02604.19 NAAE01000001_00019 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Mur_ligase_M PF08245.12 NAAG01000003_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 NAAG01000003_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 NAAG01000003_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 NAAG01000003_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 NAAG01000003_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 NAAG01000003_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 NAAG01000003_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 NAAG01000003_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 NAAG01000003_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 NAAG01000003_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 NAAG01000003_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 NAAG01000003_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 NAAG01000003_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 NAAG01000003_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 NAAG01000003_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 NAAG01000003_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 NAAG01000003_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 NAAG01000003_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 NAAG01000003_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 NAAG01000003_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 NAAG01000003_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 NAAG01000003_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 NAAG01000003_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 NAAG01000003_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 NAAG01000003_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 NAAG01000003_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 NAAG01000003_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 NAAG01000003_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 NAAG01000003_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 NAAG01000003_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 NAAG01000003_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 NAAG01000003_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 NAAG01000003_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 NAAG01000003_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 NAAG01000003_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 NAAG01000003_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 NAAG01000003_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 NAAG01000003_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 NAAG01000003_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 NAAG01000003_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 NAAG01000003_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 NAAG01000003_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 NAAG01000003_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 NAAG01000003_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 NAAG01000003_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 NAAG01000003_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 NAAG01000003_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 NAAG01000003_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 NAAG01000003_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 NAAG01000003_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 NAAG01000003_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 NAAG01000003_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 NAAG01000003_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 NAAG01000003_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 NAAG01000003_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 NAAG01000003_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 NAAG01000003_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 NAAG01000003_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 NAAG01000003_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 NAAG01000003_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 NAAG01000003_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 NAAG01000003_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 NAAG01000003_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 NAAG01000003_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 NAAG01000003_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 NAAG01000003_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 NAAG01000003_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 NAAG01000003_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 NAAG01000003_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 NAAG01000003_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 NAAG01000003_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 NAAG01000003_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 NAAG01000003_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 NAAG01000003_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 NAAG01000003_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 NAAG01000003_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 NAAG01000003_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 NAAG01000003_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 NAAG01000003_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 NAAG01000003_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 NAAG01000003_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain Mur_ligase_M PF08245.12 NAAH01000003_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 NAAH01000003_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 NAAH01000003_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 NAAH01000003_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 NAAH01000003_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 NAAH01000003_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 NAAH01000003_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 NAAH01000003_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 NAAH01000003_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 NAAH01000003_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 NAAH01000003_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 NAAH01000003_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 NAAH01000003_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 NAAH01000003_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 NAAH01000003_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 NAAH01000003_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 NAAH01000003_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 NAAH01000003_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 NAAH01000003_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 NAAH01000003_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 NAAH01000003_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 NAAH01000003_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 NAAH01000003_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 NAAH01000003_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 NAAH01000003_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 NAAH01000003_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 NAAH01000003_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 NAAH01000003_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 NAAH01000003_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 NAAH01000003_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 NAAH01000003_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 NAAH01000003_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 NAAH01000003_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 NAAH01000003_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 NAAH01000003_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 NAAH01000003_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 NAAH01000003_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 NAAH01000003_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 NAAH01000003_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 NAAH01000003_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 NAAH01000003_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 NAAH01000003_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 NAAH01000003_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 NAAH01000003_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 NAAH01000003_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 NAAH01000003_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 NAAH01000003_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 NAAH01000003_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 NAAH01000003_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 NAAH01000003_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 NAAH01000003_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 NAAH01000003_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 NAAH01000003_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 NAAH01000003_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 NAAH01000003_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 NAAH01000003_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 NAAH01000003_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 NAAH01000003_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 NAAH01000003_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 NAAH01000003_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 NAAH01000003_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 NAAH01000003_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 NAAH01000003_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 NAAH01000003_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 NAAH01000003_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 NAAH01000003_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 NAAH01000003_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 NAAH01000003_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 NAAH01000003_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 NAAH01000003_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 NAAH01000003_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 NAAH01000003_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 NAAH01000003_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 NAAH01000003_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 NAAH01000003_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 NAAH01000003_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 NAAH01000003_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 NAAH01000003_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 NAAH01000003_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 NAAH01000003_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 NAAH01000003_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain MAF_flag10 PF01973.18 NAAH01000019_00001 - 3.7e-42 143.9 0.7 5.4e-42 143.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF115 Med15_fungi PF05397.12 NAAH01000019_00001 - 0.011 16.0 0.7 0.15 12.4 0.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 GTP_EFTU PF00009.27 NC_006134_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 NC_006134_00001 - 3.7e-23 81.6 0.0 9.7e-23 80.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 NC_006134_00001 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 NC_006134_00001 - 1.3e-13 50.8 0.1 2.8e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 NC_006134_00001 - 1.3e-06 28.5 0.2 4.6e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RF3_C PF16658.5 NC_006134_00001 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 NC_006134_00001 - 0.012 16.0 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Septin PF00735.18 NC_006134_00001 - 0.02 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 NC_006134_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 NC_006134_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 NC_006134_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 NC_006134_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 NC_006134_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 NC_006134_00005 - 0.019 15.1 0.2 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 NC_006134_00006 - 0.0057 16.0 1.4 0.0057 16.0 1.4 2.0 3 0 0 3 3 3 1 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 NC_006134_00006 - 1.9 7.5 5.4 2.3 7.2 5.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LysE PF01810.18 NC_006134_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 NC_006134_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 NC_006134_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 NC_006134_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 NC_006134_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 NC_006134_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 NC_006134_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 NC_006134_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 NC_006134_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 NC_006134_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 NC_006134_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 NC_006134_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 NC_006134_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 NC_006134_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 NC_006134_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 NC_006134_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 NC_006134_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 NC_006134_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 NC_006134_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 NC_006134_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 NC_006134_00012 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 NC_006134_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 NC_006134_00012 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 NC_006134_00012 - 9.2e-06 25.5 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 NC_006134_00012 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 NC_006134_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 NC_006134_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 NC_006134_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 NC_006134_00014 - 0.00022 21.6 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 NC_006134_00014 - 0.0032 17.7 0.0 0.0079 16.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 NC_006134_00014 - 0.0091 16.0 0.3 0.017 15.2 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 NC_006134_00015 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 NC_006134_00016 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 NC_006134_00016 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 NC_006134_00016 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 NC_006134_00016 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 NC_006134_00016 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 NC_006134_00017 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 NC_006134_00017 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 NC_006134_00017 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 NC_006134_00019 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 NC_006134_00019 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 NC_006134_00019 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 NC_006134_00019 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 NC_006134_00020 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 NC_006134_00021 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 NC_006134_00021 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 NC_006134_00021 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 NC_006134_00023 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 NC_006134_00024 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 NC_006134_00025 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 NC_006134_00025 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 NC_006134_00025 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 NC_006134_00025 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 NC_006134_00025 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 NC_006134_00025 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 NC_006134_00025 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 NC_006134_00026 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 NC_006134_00026 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 NC_006134_00026 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 NC_006134_00026 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 NC_006134_00027 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.8 1 1 1 2 2 2 2 CRISPR associated protein Cas2 TrbC PF04956.13 NC_006134_00029 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 NC_006134_00029 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 NC_006134_00030 - 7.1e-51 173.2 0.4 1.6e-50 172.1 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 NC_006134_00030 - 2.6e-21 75.7 1.0 4.4e-21 74.9 1.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 NC_006134_00030 - 0.046 13.2 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 NC_006134_00031 - 1.8e-31 108.5 0.0 2.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Y_Y_Y PF07495.13 NC_006134_00031 - 0.1 12.6 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PBECR2 PF18810.1 NC_006134_00032 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 NC_006134_00033 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 NC_006134_00034 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 NC_006134_00034 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 NC_006134_00034 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 NC_006134_00034 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 NC_006134_00035 - 1e-28 101.1 13.2 1.4e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 NC_006134_00035 - 0.0082 16.3 2.4 0.021 15.0 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 NC_006134_00035 - 0.016 15.9 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain KMP11 PF03037.16 NC_006134_00035 - 0.02 15.7 0.1 0.17 12.7 0.0 2.6 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 AATF-Che1 PF13339.6 NC_006134_00035 - 0.023 15.3 12.3 0.028 15.1 5.0 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Tissue_fac PF01108.17 NC_006134_00035 - 0.029 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Tissue factor Allexi_40kDa PF05549.11 NC_006134_00035 - 1.2 8.6 6.3 1.2 8.6 2.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 NC_006134_00036 - 1.4e-29 103.5 34.4 1.4e-29 103.5 34.4 1.7 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 NC_006134_00036 - 0.097 12.5 1.3 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 NC_006134_00037 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 NC_006134_00037 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 NC_006134_00037 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 NC_006134_00038 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 NC_006134_00038 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 NC_006134_00039 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 NC_006134_00039 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 NC_006134_00039 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 NC_006134_00040 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 NC_006134_00040 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 NC_006134_00041 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 NC_006134_00041 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 NC_006134_00041 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 NC_006134_00041 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 NC_006134_00041 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 NC_006134_00041 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 NC_006134_00041 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 NC_006134_00041 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 NC_006134_00041 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 NC_006134_00041 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 NC_006134_00041 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 NC_006134_00041 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 NC_006134_00041 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 NC_006134_00041 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 NC_006134_00041 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 NC_006134_00041 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 NC_006134_00041 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 NC_006134_00041 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 NC_006134_00041 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 NC_006134_00041 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 NC_006134_00041 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 NC_006134_00041 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 NC_006134_00041 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 NC_006134_00041 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 NC_006134_00041 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 NC_006134_00041 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 NC_006134_00041 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 NC_006134_00041 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 NC_006134_00041 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 NC_006134_00041 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 NC_006134_00041 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 NC_006134_00041 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 NC_006134_00042 - 1.4e-105 353.8 0.1 1.9e-105 353.4 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 NC_006134_00042 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 NC_006134_00042 - 6.2e-16 58.3 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 NC_006134_00043 - 1e-16 61.2 0.1 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 NC_006134_00043 - 0.062 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 NC_006134_00044 - 9.5e-39 132.8 1.2 1.2e-38 132.5 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 NC_006134_00045 - 0.028 14.2 2.2 0.033 14.0 0.3 2.0 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 NC_006134_00045 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family TACC_C PF05010.14 NC_006134_00045 - 2.3 8.0 10.0 3.6 7.3 7.9 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 NC_006134_00045 - 4.6 7.4 12.1 50 4.0 9.2 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT20 PF14931.6 NC_006134_00045 - 5.4 7.2 10.4 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CdhD PF03599.16 NC_006134_00047 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 NC_006134_00047 - 0.028 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 NC_006134_00047 - 0.12 12.6 0.1 0.12 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized YnfE-like Topoisom_bac PF01131.20 NC_006134_00048 - 2.7e-97 326.4 7.4 3.8e-97 325.9 7.4 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 NC_006134_00048 - 7.1e-12 45.5 2.2 1.4e-11 44.5 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 NC_006134_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 NC_006134_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 NC_006134_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 NC_006134_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 NC_006134_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 NC_006134_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 NC_006134_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 NC_006134_00048 - 0.096 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 NC_006134_00048 - 0.1 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 NC_006134_00048 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 NC_006134_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 NC_006134_00048 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 NC_006134_00048 - 0.74 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 NC_006134_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 NC_006134_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 NC_006134_00049 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 NC_006134_00049 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 NC_006135_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 NC_006135_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 NC_006135_00001 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 NC_006135_00001 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 NC_006135_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 NC_006135_00001 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 NC_006135_00001 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 NC_006135_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 NC_006135_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 NC_006135_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 NC_006135_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 NC_006135_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 NC_006135_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 NC_006135_00005 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 NC_006135_00005 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 NC_006135_00006 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 NC_006135_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 NC_006135_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 NC_006135_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 NC_006135_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 NC_006135_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 NC_006135_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 NC_006135_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 NC_006135_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 NC_006135_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 NC_006135_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 NC_006135_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 NC_006135_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 NC_006135_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 NC_006135_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 NC_006135_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 NC_006135_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 NC_006135_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 NC_006135_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 NC_006135_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 NC_006135_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 NC_006135_00012 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 NC_006135_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 NC_006135_00012 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 NC_006135_00012 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 NC_006135_00012 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 NC_006135_00013 - 0.0008 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 NC_006135_00013 - 0.033 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 NC_006135_00014 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 NC_006135_00015 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 NC_006135_00015 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 NC_006135_00015 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 NC_006135_00015 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 NC_006135_00015 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 NC_006135_00016 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 NC_006135_00016 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 NC_006135_00016 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 NC_006135_00018 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 NC_006135_00019 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 NC_006135_00019 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 NC_006135_00019 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 NC_006135_00019 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 NC_006135_00020 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 NC_006135_00021 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 NC_006135_00021 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 NC_006135_00021 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 NC_006135_00021 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 NC_006135_00022 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 NC_006135_00022 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 NC_006135_00022 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 NC_006135_00024 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 NC_006135_00025 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 NC_006135_00026 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 NC_006135_00026 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 NC_006135_00026 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 NC_006135_00026 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 NC_006135_00026 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 NC_006135_00026 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 NC_006135_00026 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 NC_006135_00027 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 NC_006135_00027 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 NC_006135_00027 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 NC_006135_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 NC_006135_00028 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 NC_006135_00028 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 NC_006135_00030 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 NC_006135_00030 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 NC_006135_00031 - 4.8e-50 170.5 0.5 1.1e-49 169.4 0.5 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 NC_006135_00031 - 6.8e-21 74.3 1.2 1.2e-20 73.5 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 NC_006135_00031 - 0.045 13.2 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 NC_006135_00033 - 1.5e-21 76.7 0.1 2.6e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 NC_006135_00034 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 NC_006135_00034 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 NC_006135_00034 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 NC_006135_00034 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 NC_006135_00034 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 NC_006135_00034 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 NC_006135_00035 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 NC_006135_00036 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 NC_006135_00036 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 NC_006135_00037 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 NC_006135_00037 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 NC_006135_00037 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 NC_006135_00037 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 NC_006135_00037 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 NC_006135_00037 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 NC_006135_00037 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 NC_006135_00038 - 1.4e-31 110.0 32.1 1.9e-31 109.5 32.1 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Trep_dent_lipo PF09710.10 NC_006135_00039 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 NC_006135_00039 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 NC_006135_00040 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 NC_006135_00040 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 NC_006135_00041 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 NC_006135_00041 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 NC_006135_00042 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 NC_006135_00042 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 NC_006135_00043 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 NC_006135_00043 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 NC_006135_00043 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 NC_006135_00043 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 NC_006135_00043 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 NC_006135_00043 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 NC_006135_00043 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 NC_006135_00043 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 NC_006135_00043 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 NC_006135_00043 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 NC_006135_00043 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 NC_006135_00043 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 NC_006135_00043 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 NC_006135_00043 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 NC_006135_00043 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 NC_006135_00043 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 NC_006135_00043 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 NC_006135_00043 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 NC_006135_00043 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 NC_006135_00043 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 NC_006135_00043 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 NC_006135_00043 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 NC_006135_00043 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 NC_006135_00043 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 NC_006135_00043 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 NC_006135_00043 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 NC_006135_00043 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 NC_006135_00043 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 NC_006135_00043 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 NC_006135_00043 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 NC_006135_00043 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 NC_006135_00044 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 NC_006135_00044 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 NC_006135_00044 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 NC_006135_00044 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 NC_006135_00045 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 NC_006135_00045 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 NC_006135_00045 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 NC_006135_00045 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 NC_006135_00046 - 5.7e-29 101.1 0.5 6.4e-29 100.9 0.5 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 NC_006135_00047 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 NC_006135_00047 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 NC_006135_00047 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 NC_006135_00049 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 NC_006135_00050 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 NC_006135_00050 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 NC_006135_00050 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 NC_006135_00050 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 NC_006135_00050 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 NC_006135_00050 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 NC_006135_00050 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 NC_006135_00050 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 NC_006135_00050 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 NC_006135_00050 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 NC_006135_00050 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 NC_006135_00050 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 NC_006135_00050 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 NC_006135_00050 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 NC_006135_00050 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 NC_006135_00050 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 NC_006135_00050 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 NC_006135_00051 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 NC_006135_00051 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Acetyltransf_7 PF13508.7 NC_007141_00002 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 NC_007141_00002 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 NC_007141_00003 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 NC_007141_00004 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 NC_007141_00004 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 NC_007141_00004 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 NC_007141_00004 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 NC_007141_00004 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 NC_007141_00005 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 NC_007141_00005 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 NC_007141_00005 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 NC_007141_00007 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 NC_007141_00008 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 NC_007141_00008 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 NC_007141_00008 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 NC_007141_00008 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 NC_007141_00009 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 NC_007141_00010 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 NC_007141_00010 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 NC_007141_00010 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 NC_007141_00010 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 NC_007141_00011 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 NC_007141_00011 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 NC_007141_00011 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 NC_007141_00013 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 NC_007141_00014 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 NC_007141_00015 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 NC_007141_00015 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 NC_007141_00015 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 NC_007141_00015 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 NC_007141_00015 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 NC_007141_00015 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 NC_007141_00015 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 NC_007141_00016 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 NC_007141_00016 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 NC_007141_00016 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 NC_007141_00016 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 NC_007141_00017 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 NC_007141_00017 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 NC_007141_00019 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 NC_007141_00019 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 NC_007141_00020 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 NC_007141_00020 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 NC_007141_00020 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 NC_007141_00021 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 NC_007141_00022 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 NC_007141_00022 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 NC_007141_00022 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 NC_007141_00022 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 NC_007141_00022 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 NC_007141_00022 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 NC_007141_00023 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 NC_007141_00024 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 NC_007141_00024 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 NC_007141_00025 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 NC_007141_00025 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 NC_007141_00025 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 NC_007141_00025 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 NC_007141_00025 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 NC_007141_00025 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 NC_007141_00025 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 NC_007141_00026 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 NC_007141_00026 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 NC_007141_00026 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 NC_007141_00027 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 NC_007141_00027 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 NC_007141_00028 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 NC_007141_00028 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 NC_007141_00029 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 NC_007141_00029 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 NC_007141_00030 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 NC_007141_00030 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 NC_007141_00031 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 NC_007141_00031 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 NC_007141_00031 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 NC_007141_00031 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 NC_007141_00031 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 NC_007141_00031 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 NC_007141_00031 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 NC_007141_00031 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 NC_007141_00031 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 NC_007141_00031 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 NC_007141_00031 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 NC_007141_00031 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 NC_007141_00031 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 NC_007141_00031 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 NC_007141_00031 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 NC_007141_00031 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 NC_007141_00031 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 NC_007141_00031 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 NC_007141_00031 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 NC_007141_00031 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 NC_007141_00031 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 NC_007141_00031 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 NC_007141_00031 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 NC_007141_00031 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 NC_007141_00031 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 NC_007141_00031 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 NC_007141_00031 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 NC_007141_00031 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 NC_007141_00031 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 NC_007141_00031 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 NC_007141_00031 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 NC_007141_00032 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 NC_007141_00032 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 NC_007141_00032 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 NC_007141_00032 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 NC_007141_00033 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 NC_007141_00033 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 NC_007141_00033 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 NC_007141_00033 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 NC_007141_00034 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 NC_007141_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 NC_007141_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 NC_007141_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 NC_007141_00037 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 NC_007141_00038 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 NC_007141_00038 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 NC_007141_00038 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 NC_007141_00038 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 NC_007141_00038 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 NC_007141_00038 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 NC_007141_00038 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 NC_007141_00038 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 NC_007141_00038 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 NC_007141_00038 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 NC_007141_00038 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 NC_007141_00038 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 NC_007141_00038 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 NC_007141_00038 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 NC_007141_00038 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 NC_007141_00038 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 NC_007141_00038 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 NC_007141_00039 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 NC_007141_00039 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 NC_007141_00041 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 NC_007141_00041 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 NC_007141_00041 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 NC_007141_00041 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 NC_007141_00041 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 NC_007141_00041 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 NC_007141_00041 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 NC_007141_00041 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 NC_007141_00041 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 NC_007141_00041 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 NC_007141_00042 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 NC_007141_00044 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 NC_007141_00044 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 NC_007141_00045 - 0.039 14.1 0.2 4.3 7.5 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 NC_007141_00046 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DUF1516 PF07457.11 NC_007141_00047 - 0.0042 17.3 0.4 0.0049 17.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) LysE PF01810.18 NC_007141_00047 - 0.0049 16.4 0.1 0.0057 16.1 0.1 1.1 1 0 0 1 1 1 1 LysE type translocator DUF2873 PF11395.8 NC_007141_00047 - 1 9.3 0.1 1 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2873) S1_2 PF13509.6 NC_007141_00048 - 0.093 12.8 0.5 0.85 9.7 0.1 2.0 1 1 1 2 2 2 0 S1 domain DUF4044 PF13253.6 NC_007141_00049 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 NC_007141_00049 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 NC_007141_00049 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 NC_007141_00049 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 NC_007141_00049 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 NC_007141_00050 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 NC_007141_00050 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 NC_007141_00051 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 NC_007141_00051 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 NC_007141_00051 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 NC_007141_00051 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 NC_007141_00051 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 NC_007141_00052 - 5.4e-07 29.9 1.0 5.9e-07 29.8 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG PDDEXK_9 PF08011.11 NC_007141_00053 - 0.017 15.0 0.2 0.032 14.1 0.2 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF5445 PF17520.2 NC_007141_00054 - 1 9.2 12.2 1.3 8.9 11.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5445) W2 PF02020.18 NC_008790_00001 - 0.037 14.2 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 NC_008790_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 NC_008790_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 NC_008790_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 NC_008790_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 NC_008790_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 NC_008790_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 NC_008790_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 NC_008790_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 NC_008790_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 NC_008790_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 NC_008790_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 NC_008790_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 NC_008790_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 NC_008790_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 NC_008790_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 NC_008790_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 NC_008790_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 NC_008790_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 NC_008790_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 NC_008790_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 NC_008790_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 NC_008790_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 NC_008790_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 NC_008790_00009 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 NC_008790_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 NC_008790_00009 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 NC_008790_00009 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 NC_008790_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 NC_008790_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 NC_008790_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 NC_008790_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 NC_008790_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 NC_008790_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 NC_008790_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 NC_008790_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 NC_008790_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 NC_008790_00013 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 NC_008790_00013 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 NC_008790_00013 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 NC_008790_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 NC_008790_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 NC_008790_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 NC_008790_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 NC_008790_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 NC_008790_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 NC_008790_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 NC_008790_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 NC_008790_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 NC_008790_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 NC_008790_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 NC_008790_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 NC_008790_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 NC_008790_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 NC_008790_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 NC_008790_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 NC_008790_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 NC_008790_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 NC_008790_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 NC_008790_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 NC_008790_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 NC_008790_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 NC_008790_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 NC_008790_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 NC_008790_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 NC_008790_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 NC_008790_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 NC_008790_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 NC_008790_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 NC_008790_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 NC_008790_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 NC_008790_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 NC_008790_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 NC_008790_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 NC_008790_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 NC_008790_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 NC_008790_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 NC_008790_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 NC_008790_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 NC_008790_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 NC_008790_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 NC_008790_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 NC_008790_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 NC_008790_00033 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 NC_008790_00033 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 NC_008790_00033 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 NC_008790_00033 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 NC_008790_00033 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 NC_008790_00033 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 NC_008790_00033 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 NC_008790_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 NC_008790_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 NC_008790_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 NC_008790_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 NC_008790_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 NC_008790_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 NC_008790_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 NC_008790_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 NC_008790_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 NC_008790_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 NC_008790_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 NC_008790_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 NC_008790_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 NC_008790_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 NC_008790_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 NC_008790_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 NC_008790_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 NC_008790_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 NC_008790_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 NC_008790_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 NC_008790_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 NC_008790_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 NC_008790_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 NC_008790_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 NC_008790_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 NC_008790_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 NC_008790_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 NC_008790_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 NC_008790_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 NC_008790_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 NC_008790_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 NC_008790_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 NC_008790_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 NC_008790_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 NC_008790_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 NC_008790_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 NC_008790_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 NC_008790_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 NC_008790_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 NC_008790_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 NC_008790_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 NC_008790_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 NC_008790_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 NC_008790_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 NC_008790_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 NC_008790_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 NC_008790_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 NC_008790_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 NC_008790_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 NC_008790_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 NC_008790_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 NC_008790_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 NC_008790_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 NC_008790_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 NC_008790_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 NC_008790_00046 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 NC_008790_00046 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 NC_008790_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 NC_008790_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 NC_008790_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 NC_008790_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 NC_008790_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 NC_008790_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 NC_008790_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 NC_008790_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 NC_008790_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 NC_008790_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 NC_008790_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 NC_008790_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 NC_008790_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 NC_008790_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 NC_008790_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 NC_008790_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 NC_008790_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 NC_008790_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 NC_008790_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 NC_008790_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 NC_008790_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 NC_008790_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 NC_008790_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 NC_008790_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 NC_008790_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 NC_008790_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 NC_008790_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 NC_008790_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 NC_022355_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 NC_022355_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 NC_022355_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 NC_022355_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain DHHC PF01529.20 NC_022355_00004 - 4.1 7.5 13.1 13 5.9 13.1 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4133 PF13571.6 NC_022355_00004 - 5.6 7.4 7.4 7.5 7.0 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) DHHC PF01529.20 NC_022355_00006 - 0.033 14.3 6.3 0.039 14.0 6.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase T4SS_CagC PF16943.5 NC_022355_00006 - 0.046 13.9 0.2 0.056 13.6 0.2 1.1 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF4044 PF13253.6 NC_022355_00008 - 0.035 13.6 0.8 0.062 12.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 NC_022355_00008 - 0.065 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2070 PF09843.9 NC_022355_00008 - 0.072 11.4 1.1 0.11 10.8 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 NC_022355_00008 - 9.1 6.0 13.6 0.15 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 NC_022355_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 NC_022355_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) adh_short PF00106.25 NC_022355_00010 - 0.034 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 NC_022355_00010 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 NC_022355_00011 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 NC_022355_00011 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 NC_022355_00012 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 NC_022355_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 NC_022355_00012 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 NC_022355_00012 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 NC_022355_00012 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 NC_022355_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 NC_022355_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 NC_022355_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 NC_022355_00014 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 NC_022355_00014 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 NC_022355_00014 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 NC_022355_00014 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 NC_022355_00014 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 NC_022355_00014 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 NC_022355_00015 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 NC_022355_00016 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 NC_022355_00017 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 NC_022355_00017 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 NC_022355_00017 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 NC_022355_00017 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 NC_022355_00017 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 NC_022355_00018 - 1.1 9.1 11.3 0.26 11.1 5.3 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 NC_022355_00018 - 1.4 9.3 6.9 0.31 11.3 1.2 2.1 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 NC_022355_00018 - 1.7 8.7 15.5 0.15 12.1 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function Ribonuc_2-5A PF06479.12 NC_022355_00022 - 0.065 13.4 5.2 0.2 11.9 5.2 1.9 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF5311 PF17238.2 NC_022355_00022 - 0.065 13.1 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Toprim_3 PF13362.6 NC_022355_00023 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 NC_022355_00023 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 NC_022355_00023 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 NC_022355_00023 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 NC_022355_00024 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 NC_022355_00024 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 NC_022355_00025 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 NC_022355_00025 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 NC_022355_00025 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 NC_022355_00027 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 NC_022355_00028 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 NC_022355_00029 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 NC_022355_00029 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 NC_022355_00029 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 NC_022355_00029 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 NC_022355_00029 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 NC_022355_00029 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 NC_022355_00029 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 NC_022355_00030 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 NC_022355_00030 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 NC_022355_00030 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 NC_022355_00031 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 NC_022355_00033 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 NC_022355_00033 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 NC_022355_00034 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 NC_022355_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 NC_022355_00035 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 NC_022355_00035 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 NC_022355_00035 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 NC_022355_00036 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 NC_022355_00037 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 NC_022355_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 NC_022355_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 NC_022355_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 NC_022355_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 NC_022355_00039 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 NC_022355_00039 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 NC_022355_00039 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 NC_022355_00039 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 NC_022355_00040 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 NC_022355_00040 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 NC_022355_00040 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 NC_022355_00040 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 NC_022355_00041 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 NC_022355_00042 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 NC_022355_00042 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 NC_022355_00043 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 NC_022355_00044 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 NC_022355_00044 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 NC_022355_00045 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 NC_022355_00045 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 NC_022355_00045 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 NC_022355_00045 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 NC_022355_00045 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 NC_022355_00045 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 NC_022355_00045 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 NC_022355_00045 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 NC_022355_00045 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 NC_022355_00045 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 NC_022355_00045 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 NC_022355_00045 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 NC_022355_00045 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 NC_022355_00045 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 NC_022355_00045 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 NC_022355_00045 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 NC_022355_00045 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 NC_022355_00045 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 NC_022355_00045 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 NC_022355_00045 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 NC_022355_00045 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 NC_022355_00045 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 NC_022355_00045 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 NC_022355_00045 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 NC_022355_00045 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 NC_022355_00045 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 NC_022355_00045 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 NC_022355_00045 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 NC_022355_00045 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 NC_022355_00045 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 NC_022355_00045 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 NC_022355_00045 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 NC_022355_00046 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 NC_022355_00047 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 NC_022355_00047 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 NC_022355_00047 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 NC_022355_00047 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 NC_022355_00047 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 NC_022355_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 NC_022355_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 NC_022355_00049 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 NC_022355_00050 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 NC_022355_00050 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 NC_022355_00051 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 NC_022355_00051 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 NC_022355_00051 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 NC_022355_00052 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 NC_022355_00053 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 NC_022355_00053 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 NC_022355_00053 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 NC_022355_00053 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 NC_022355_00053 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 NC_022355_00053 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 NC_022355_00053 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 NC_022355_00053 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 NC_022355_00053 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 NC_022355_00053 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 NC_022355_00053 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 NC_022355_00053 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 NC_022355_00053 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 NC_022355_00053 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 NC_022355_00053 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 NC_022355_00053 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 NC_022355_00053 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 NC_022355_00054 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 NC_022355_00054 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain APH PF01636.23 NC_022355_00056 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 NC_022355_00056 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 NC_022355_00056 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 NC_022355_00056 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 NC_022355_00056 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 NC_022355_00057 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 NC_022355_00057 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 NC_022355_00057 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 NC_022355_00057 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 NC_022355_00057 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 NC_022355_00057 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 NC_022355_00057 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 NC_022355_00057 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 NC_022355_00057 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 NC_022355_00059 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 NC_022355_00059 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 NC_022355_00059 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 NC_022355_00059 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 NC_022355_00059 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 NC_022355_00060 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 NC_022355_00061 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 NC_022355_00061 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 NC_022355_00061 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 NC_022355_00061 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 NC_022355_00062 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 NC_022355_00063 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 NC_022355_00063 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 NC_022355_00063 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 NC_022355_00063 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 NC_022355_00063 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 NC_022355_00063 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 NC_022355_00063 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 NC_022355_00063 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 NC_022355_00063 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 NC_022355_00063 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 NC_022355_00063 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 NC_022355_00063 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 NC_022355_00063 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 NC_022355_00063 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 NC_022355_00063 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 NC_022355_00063 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 NC_022355_00063 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 NC_022355_00063 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 NC_022355_00063 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 NC_022355_00063 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 NC_022355_00063 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 NC_022355_00063 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 NC_022355_00063 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 NC_022355_00063 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 NC_022355_00063 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 NC_022355_00063 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 NC_022355_00063 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 NC_022355_00063 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 NC_022355_00063 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 NC_022355_00063 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 NC_022355_00063 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 NC_022355_00063 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 NC_022355_00063 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 NC_022355_00063 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 NC_022355_00063 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 NC_022355_00063 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 NC_022355_00063 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 NC_022355_00064 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 NC_022355_00064 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 NC_022355_00064 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 NC_022355_00064 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 NC_022355_00064 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 NC_022355_00064 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 NC_022355_00065 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 NC_022355_00066 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 NC_022355_00067 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 NC_022355_00067 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 NC_022355_00067 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 NC_022355_00067 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 NC_022355_00067 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 NC_022355_00067 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 NC_022355_00067 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 NC_022355_00067 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 NC_022355_00068 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 NC_022355_00068 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 NC_022355_00068 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 NC_022355_00069 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 NC_022355_00069 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 NC_022355_00069 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 NC_022355_00070 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 NC_022355_00070 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 NC_022355_00070 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Reticulon PF02453.17 pAAFJ01000010_00004 - 0.011 15.7 3.4 0.011 15.7 3.4 1.2 1 0 0 1 1 1 0 Reticulon TK PF00265.18 pAAFJ01000010_00005 - 7e-20 71.6 1.2 1.6e-19 70.5 1.2 1.6 1 1 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 pAAFJ01000010_00005 - 0.003 17.6 0.3 0.004 17.2 0.3 1.2 1 0 0 1 1 1 1 AAA domain Terminase_6 PF03237.15 pAAFJ01000010_00005 - 0.0088 15.7 0.4 0.03 14.0 0.4 1.9 1 1 0 1 1 1 1 Terminase-like family FcoT PF10862.8 pAAFJ01000010_00006 - 0.031 13.9 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 FcoT-like thioesterase domain ECH_2 PF16113.5 pAAFJ01000010_00006 - 0.044 13.3 0.5 0.045 13.3 0.5 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase EF-hand_7 PF13499.6 pAAFJ01000010_00006 - 0.068 13.6 0.2 2.6 8.5 0.2 2.1 1 1 0 1 1 1 0 EF-hand domain pair DUF3973 PF13119.6 pAAFJ01000010_00007 - 0.088 12.9 2.7 0.35 11.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Toprim_2 PF13155.6 pAAFJ01000010_00010 - 2.2e-11 44.0 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.6 pAAFJ01000010_00010 - 4.2e-05 23.8 0.0 8.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.20 pAAFJ01000010_00010 - 0.0061 16.4 0.1 0.037 13.8 0.1 2.2 2 0 0 2 2 2 1 CHC2 zinc finger DUF3854 PF12965.7 pAAFJ01000010_00010 - 0.094 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) CSN8_PSD8_EIF3K PF10075.9 pAAFJ01000010_00011 - 0.31 11.0 4.2 0.29 11.1 0.8 2.2 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family Peptidase_C39 PF03412.15 pAAFJ01000010_00015 - 2.5e-17 62.9 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pAAFJ01000010_00015 - 3e-05 24.0 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Phage_integrase PF00589.22 pAAFJ01000010_00017 - 2.8e-20 72.8 2.1 4.4e-20 72.2 2.1 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pAAFJ01000010_00017 - 5.5e-05 23.4 2.7 0.081 13.2 0.1 3.1 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pAAFJ01000010_00017 - 0.00022 21.5 8.0 0.00022 21.5 8.0 2.7 2 2 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pAAFJ01000010_00017 - 0.0026 18.2 5.5 0.0026 18.2 5.5 2.5 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 pAAFJ01000010_00017 - 0.0035 17.5 0.4 0.0067 16.5 0.4 1.5 1 0 0 1 1 1 1 Integrase Phage_int_SAM_6 PF18644.1 pAAFJ01000010_00017 - 3.7 7.6 16.4 0.77 9.8 0.9 3.2 3 1 1 4 4 4 0 Phage integrase SAM-like domain HMG-CoA_red PF00368.18 pAAFJ01000010_00018 - 0.083 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase WGR PF05406.15 pAAFJ01000010_00019 - 0.00012 22.0 0.3 0.00014 21.8 0.3 1.1 1 0 0 1 1 1 1 WGR domain Latarcin PF10279.9 pAAFJ01000010_00019 - 0.01 16.2 0.1 0.015 15.7 0.1 1.2 1 0 0 1 1 1 0 Latarcin precursor Tantalus PF15386.6 pAAFJ01000010_00019 - 0.047 13.8 0.1 0.047 13.8 0.1 1.9 1 1 1 2 2 2 0 Drosophila Tantalus-like PPR_2 PF13041.6 pAAFJ01000010_00019 - 0.14 12.4 0.9 0.23 11.7 0.9 1.4 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.20 pAAFJ01000010_00019 - 0.23 11.8 1.6 0.31 11.4 0.7 1.6 2 0 0 2 2 2 0 PPR repeat HD PF01966.22 pAAFJ01000010_00021 - 1.8e-10 41.1 0.9 3.6e-10 40.1 0.9 1.6 1 0 0 1 1 1 1 HD domain HD_6 PF18019.1 pAAFJ01000010_00021 - 0.029 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 HD domain TrwB_AAD_bind PF10412.9 pAAFJ01000010_00022 - 4e-17 62.2 0.0 6.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 pAAFJ01000010_00022 - 2e-15 56.6 0.5 2.7e-15 56.2 0.5 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pAAFJ01000010_00022 - 1.3e-10 41.3 0.1 2.7e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG DUF87 PF01935.17 pAAFJ01000010_00022 - 1.2e-05 25.6 0.5 2.9e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_10 PF12846.7 pAAFJ01000010_00022 - 1.3e-05 24.3 0.3 0.012 14.5 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain DUF853 PF05872.12 pAAFJ01000010_00022 - 0.0034 16.0 0.0 0.0076 14.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 pAAFJ01000010_00022 - 0.007 16.6 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pAAFJ01000010_00022 - 0.016 15.6 0.0 0.078 13.4 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 pAAFJ01000010_00022 - 0.018 14.9 0.1 0.064 13.2 0.1 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 pAAFJ01000010_00022 - 0.034 14.7 0.1 0.097 13.2 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 pAAFJ01000010_00022 - 0.042 13.1 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF1548 PF07579.11 pAAFJ01000010_00022 - 0.11 12.8 1.9 0.44 10.9 0.2 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) FtsK_SpoIIIE PF01580.18 pAAFJ01000010_00022 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArlS_N PF18719.1 pAAFJ01000010_00022 - 0.91 9.7 4.0 2.1 8.6 0.2 2.5 2 1 0 2 2 2 0 ArlS sensor domain OSTMP1 PF09777.9 pAAFJ01000010_00023 - 1.2 8.5 3.2 6.1 6.2 0.3 2.3 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor MnmE_helical PF12631.7 pAAFJ01000010_00024 - 0.44 10.7 1.7 0.7 10.0 1.7 1.5 1 1 0 1 1 1 0 MnmE helical domain HTH_3 PF01381.22 pAAFJ01000010_00025 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pAAFJ01000010_00025 - 1.2e-08 34.8 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 pAAFJ01000010_00025 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain APG12 PF04110.13 pAAFJ01000010_00025 - 0.1 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 AAA_19 PF13245.6 pAAFJ01000010_00026 - 6.3e-14 52.5 0.2 4.6e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 pAAFJ01000010_00026 - 6.5e-12 45.6 17.8 8.3e-10 38.7 1.7 4.0 1 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 pAAFJ01000010_00026 - 6.1e-11 42.5 0.3 2.8e-05 24.0 0.1 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 pAAFJ01000010_00026 - 4.3e-10 39.5 16.6 4.7e-10 39.4 12.7 2.5 1 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 pAAFJ01000010_00026 - 6e-09 35.6 0.0 4.8e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 pAAFJ01000010_00026 - 8.1e-06 25.7 0.0 0.0045 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 pAAFJ01000010_00026 - 0.00049 19.6 0.2 0.47 9.9 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein DUF2075 PF09848.9 pAAFJ01000010_00026 - 0.02 14.2 0.3 3.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Peptidase_M6 PF05547.11 pAAFJ01000010_00026 - 0.025 12.9 0.1 0.037 12.4 0.1 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Helicase_RecD PF05127.14 pAAFJ01000010_00026 - 0.04 13.8 0.7 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Helicase AAA_11 PF13086.6 pAAFJ01000010_00026 - 0.11 12.3 0.5 19 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 pAAFJ01000010_00026 - 0.34 10.9 8.2 0.065 13.2 1.8 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Thioredoxin_7 PF13899.6 pAAFJ01000010_00027 - 4.1e-05 23.7 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 pAAFJ01000010_00027 - 0.00038 20.9 0.4 0.0011 19.4 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 pAAFJ01000010_00027 - 0.047 13.6 0.2 0.055 13.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF255 Redoxin PF08534.10 pAAFJ01000010_00027 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin TrbC_Ftype PF09673.10 pAAFJ01000010_00028 - 2e-16 60.0 0.0 3.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein DUF1694 PF07997.11 pAAFJ01000010_00028 - 0.0015 18.6 0.5 0.0085 16.2 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1694) DUF3502 PF12010.8 pAAFJ01000010_00028 - 0.028 15.0 2.0 0.028 15.0 2.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3502) Thioredoxin PF00085.20 pAAFJ01000010_00028 - 0.039 14.0 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 Thioredoxin TraU PF06834.11 pAAFJ01000010_00029 - 9.6e-97 323.9 0.0 1.1e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 TraU protein RhoGAP PF00620.27 pAAFJ01000010_00031 - 0.0012 18.7 1.6 0.0012 18.7 1.6 1.7 2 0 0 2 2 2 1 RhoGAP domain DUF4252 PF14060.6 pAAFJ01000010_00031 - 0.32 10.9 8.4 0.086 12.7 4.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4252) ALP_N PF17989.1 pAAFJ01000010_00034 - 7.7e-13 48.9 0.1 1.3e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 Actin like proteins N terminal domain FtsA PF14450.6 pAAFJ01000010_00034 - 0.00018 21.9 0.2 0.099 13.1 0.0 2.4 2 1 0 2 2 2 2 Cell division protein FtsA DUF4879 PF16219.5 pAAFJ01000010_00035 - 0.0012 19.0 0.2 0.0013 18.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4879) YopX PF09643.10 pAAFJ01000010_00036 - 3e-12 46.7 2.7 2.3e-11 43.9 1.0 2.2 1 1 1 2 2 2 2 YopX protein DUF4600 PF15372.6 pAAFJ01000010_00037 - 0.0093 16.4 0.2 0.011 16.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) TMF_TATA_bd PF12325.8 pAAFJ01000010_00037 - 0.023 14.9 0.1 0.035 14.3 0.1 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YopX PF09643.10 pAAFJ01000010_00038 - 2.8e-08 33.9 0.6 4e-08 33.4 0.6 1.3 1 1 0 1 1 1 1 YopX protein HTH_17 PF12728.7 pAAFJ01000010_00041 - 2.5e-07 30.7 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pAAFJ01000010_00041 - 1.6e-05 24.8 0.0 0.067 13.3 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix HTH_19 PF12844.7 pAAFJ01000010_00041 - 6.8e-05 22.8 0.5 0.0032 17.4 0.2 2.7 1 1 1 2 2 2 2 Helix-turn-helix domain MerR PF00376.23 pAAFJ01000010_00041 - 0.00015 21.4 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 MerR family regulatory protein HTH_26 PF13443.6 pAAFJ01000010_00041 - 0.0011 19.4 0.1 0.26 11.8 0.1 2.6 2 1 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain Phage_CI_repr PF07022.13 pAAFJ01000010_00041 - 0.0014 18.7 0.0 0.0073 16.4 0.0 2.0 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain Terminase_5 PF06056.12 pAAFJ01000010_00041 - 0.0024 17.7 0.2 0.037 13.9 0.0 2.6 2 1 1 3 3 3 1 Putative ATPase subunit of terminase (gpP-like) HTH_Crp_2 PF13545.6 pAAFJ01000010_00041 - 0.0028 17.6 0.0 0.053 13.5 0.0 2.5 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 pAAFJ01000010_00041 - 0.0046 16.7 0.0 2.2 8.2 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain MerR_1 PF13411.6 pAAFJ01000010_00041 - 0.0086 16.2 0.0 1.1 9.4 0.0 2.6 2 1 0 2 2 2 1 MerR HTH family regulatory protein SL4P PF17618.2 pAAFJ01000010_00041 - 0.026 14.6 1.6 4.7 7.3 0.3 2.5 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Vps4_C PF09336.10 pAAFJ01000010_00041 - 0.036 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Phage_terminase PF10668.9 pAAFJ01000010_00041 - 0.054 13.5 0.1 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Phage terminase small subunit SNase PF00565.17 pAAFJ01000010_00042 - 5.7e-24 84.7 0.4 9.2e-24 84.0 0.4 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue O-antigen_lig PF13425.6 pAAFJ01000010_00042 - 0.022 13.6 4.2 0.027 13.3 4.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4065 PF13274.6 pAAFJ01000010_00043 - 0.001 19.9 0.8 0.0013 19.6 0.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4065) N6_N4_Mtase PF01555.18 pAAFJ01000010_00044 - 3.2e-15 56.5 7.5 1.5e-08 34.6 1.9 3.5 3 1 0 3 3 3 2 DNA methylase UPF0020 PF01170.18 pAAFJ01000010_00044 - 4.1e-06 26.6 0.0 0.051 13.3 0.0 2.6 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 pAAFJ01000010_00044 - 0.0038 16.9 0.0 0.5 10.0 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 AviRa PF11599.8 pAAFJ01000010_00044 - 0.021 14.3 0.6 0.12 11.8 0.0 2.3 3 0 0 3 3 3 0 RRNA methyltransferase AviRa Stork_head PF10264.9 pAAFJ01000010_00044 - 0.049 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain N6_N4_Mtase PF01555.18 pAAFJ01000010_00045 - 9.5e-26 90.9 0.2 2e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Methyltransf_25 PF13649.6 pAAFJ01000010_00045 - 2.4e-08 34.6 0.0 1.7e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 pAAFJ01000010_00045 - 3.1e-08 34.2 0.0 2.9e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 pAAFJ01000010_00045 - 6.3e-08 32.5 0.1 1.2e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 pAAFJ01000010_00045 - 2.1e-06 27.4 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 pAAFJ01000010_00045 - 4.7e-05 23.2 0.1 0.0016 18.1 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 pAAFJ01000010_00045 - 0.0002 21.0 0.1 0.00089 18.9 0.0 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 pAAFJ01000010_00045 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 pAAFJ01000010_00045 - 0.0058 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 pAAFJ01000010_00045 - 0.024 15.4 0.0 0.068 13.9 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 pAAFJ01000010_00045 - 0.027 14.3 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 pAAFJ01000010_00045 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1883 PF08980.10 pAAFJ01000010_00046 - 0.15 12.0 0.3 0.41 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) ParE_toxin PF05016.15 pAAFJ01000010_00047 - 3.8e-09 37.0 0.2 4.7e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 pAAFJ01000010_00047 - 0.0008 19.7 0.2 0.00099 19.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ IKKbetaNEMObind PF12179.8 pAAFJ01000010_00047 - 0.09 12.8 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain RHH_5 PF07878.11 pAAFJ01000010_00048 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 RHH_3 PF12651.7 pAAFJ01000010_00048 - 0.00048 20.0 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix domain HicB_lk_antitox PF15919.5 pAAFJ01000010_00048 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system CcdA PF07362.12 pAAFJ01000010_00048 - 0.025 15.0 0.1 0.034 14.6 0.1 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA PuR_N PF09182.10 pAAFJ01000010_00048 - 0.16 11.9 0.1 0.2 11.6 0.1 1.3 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal Bro-N PF02498.17 pAAFJ01000010_00049 - 1.6e-22 80.0 2.7 1.9e-22 79.8 0.0 2.2 2 1 0 2 2 2 1 BRO family, N-terminal domain HTH_3 PF01381.22 pAAFJ01000010_00049 - 2e-07 31.0 0.1 6.7e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pAAFJ01000010_00049 - 4.5e-07 29.8 0.1 4.5e-07 29.8 0.1 3.0 4 0 0 4 4 4 1 Helix-turn-helix domain ZapD PF07072.11 pAAFJ01000010_00049 - 0.00027 20.7 3.0 0.014 15.2 0.1 2.7 2 1 0 2 2 2 2 Cell division protein HTH_31 PF13560.6 pAAFJ01000010_00049 - 0.0048 17.2 0.0 0.0092 16.3 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain SLT PF01464.20 pAAFJ01000010_00050 - 3.1e-22 78.4 0.0 3.6e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 pAAFJ01000010_00050 - 0.017 15.6 0.2 0.035 14.6 0.2 1.6 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Lys PF00062.20 pAAFJ01000010_00050 - 0.07 13.4 0.1 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family UPF0146 PF03686.13 pAAFJ01000010_00050 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) YafQ_toxin PF15738.5 pAAFJ01000010_00052 - 9.3e-26 90.0 0.7 1.1e-25 89.8 0.7 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ASL_C PF08328.11 pAAFJ01000010_00052 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DDE_Tnp_1_7 PF13843.6 pAAFJ01000010_00053 - 0.0083 15.5 1.0 0.009 15.3 1.0 1.2 1 0 0 1 1 1 1 Transposase IS4 LETM1 PF07766.13 pAAFJ01000010_00053 - 0.009 15.4 4.8 0.01 15.2 4.8 1.2 1 0 0 1 1 1 1 LETM1-like protein Baculo_p24 PF05073.12 pAAFJ01000010_00053 - 0.035 13.9 2.5 0.038 13.8 2.5 1.0 1 0 0 1 1 1 0 Baculovirus P24 capsid protein PIEZO PF15917.5 pAAFJ01000010_00053 - 0.073 12.5 5.7 0.084 12.3 5.7 1.1 1 0 0 1 1 1 0 Piezo DUF4446 PF14584.6 pAAFJ01000010_00053 - 1.3 9.0 6.0 1.6 8.7 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Oxidored_q3 PF00499.20 pAAFJ01000010_00054 - 0.0036 17.0 0.2 0.0052 16.5 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TctA PF01970.16 pAAFJ01000010_00054 - 0.016 14.0 0.6 0.022 13.5 0.6 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Carbpep_Y_N PF05388.11 pAAFJ01000010_00054 - 0.027 15.0 2.7 0.027 15.0 0.8 1.8 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Phage_holin_3_6 PF07332.11 pAAFJ01000010_00054 - 0.11 12.6 0.3 0.18 11.9 0.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RseC_MucC PF04246.12 pAAFJ01000010_00054 - 0.13 12.2 1.3 0.21 11.6 1.3 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 pAAFJ01000010_00054 - 0.27 10.0 7.3 0.35 9.6 7.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spore_YhaL PF14147.6 pAAFJ01000010_00054 - 4 7.2 5.2 1.7 8.4 0.6 2.5 2 1 0 2 2 2 0 Sporulation protein YhaL Bacillus_PapR PF05968.11 pAAFJ01000010_00055 - 0.022 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Bacillus PapR protein YtpI PF14007.6 pAAFJ01000010_00055 - 0.024 14.8 9.1 0.038 14.1 0.1 2.9 2 1 1 3 3 3 0 YtpI-like protein TraL PF07178.11 pAAFJ01000010_00056 - 3.1e-13 50.0 0.5 3.6e-13 49.8 0.5 1.1 1 0 0 1 1 1 1 TraL protein TraE PF05309.11 pAAFJ01000010_00057 - 1e-32 113.0 0.8 1.3e-32 112.7 0.8 1.0 1 0 0 1 1 1 1 TraE protein TraK PF06586.11 pAAFJ01000010_00058 - 8.9e-23 81.2 0.2 2.6e-22 79.7 0.2 1.6 1 1 0 1 1 1 1 TraK protein TrbI PF03743.14 pAAFJ01000010_00059 - 4.8e-35 121.1 1.5 8e-35 120.4 1.5 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein Cep57_CLD PF14073.6 pAAFJ01000010_00059 - 0.0019 18.2 4.7 0.0019 18.2 4.7 2.1 2 1 0 2 2 2 1 Centrosome localisation domain of Cep57 O-antigen_lig PF13425.6 pAAFJ01000010_00059 - 0.08 11.7 8.5 0.13 11.0 8.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YrzK PF17449.2 pAAFJ01000010_00059 - 0.35 11.2 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized YrzK-like YabA PF06156.13 pAAFJ01000010_00059 - 0.61 10.8 11.7 0.061 14.0 5.6 2.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF4481 PF14800.6 pAAFJ01000010_00059 - 9 5.7 6.3 1.5 8.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Thioredoxin_2 PF13098.6 pAAFJ01000010_00060 - 1.4e-15 57.6 0.2 3.5e-15 56.4 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain DsbC_N PF10411.9 pAAFJ01000010_00060 - 8.2e-10 38.0 0.1 1.5e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 pAAFJ01000010_00060 - 0.0014 18.8 4.8 0.39 10.9 0.3 2.4 1 1 1 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 pAAFJ01000010_00060 - 0.0033 17.6 0.1 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 pAAFJ01000010_00060 - 0.086 12.7 0.1 6 6.6 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 pAAFJ01000010_00060 - 0.1 12.9 1.3 0.39 11.1 0.7 2.2 2 1 0 2 2 2 0 Thioredoxin-like DUF393 PF04134.12 pAAFJ01000010_00060 - 0.14 13.5 0.0 0.33 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF393 SH3_3 PF08239.11 pAAFJ01000010_00061 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain TraV PF09676.10 pAAFJ01000010_00061 - 0.00078 20.4 1.2 0.00078 20.4 1.2 2.5 2 1 0 2 2 2 1 Type IV conjugative transfer system lipoprotein (TraV) DUF3410 PF11890.8 pAAFJ01000010_00061 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) SH3_3 PF08239.11 pAAFJ01000010_00062 - 0.00054 20.2 0.1 0.00093 19.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain PBP_dimer PF03717.15 pAAFJ01000010_00062 - 0.027 14.8 0.7 0.035 14.4 0.7 1.1 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Closter_coat PF01785.17 pAAFJ01000010_00062 - 0.064 12.5 0.2 0.088 12.1 0.2 1.1 1 0 0 1 1 1 0 Closterovirus coat protein TraC_F_IV PF11130.8 pAAFJ01000010_00064 - 5.7e-32 111.2 0.0 2.1e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 pAAFJ01000010_00064 - 1.6e-10 40.5 0.2 9.3e-10 38.0 0.2 2.0 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 pAAFJ01000010_00064 - 5.1e-08 32.2 0.0 0.0045 15.9 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 pAAFJ01000010_00064 - 0.0013 19.1 0.4 2.3 8.5 0.0 3.2 2 1 0 3 3 3 2 AAA domain ResIII PF04851.15 pAAFJ01000010_00064 - 0.0024 17.9 2.1 0.057 13.4 0.2 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CbiA PF01656.23 pAAFJ01000010_00064 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zot PF05707.12 pAAFJ01000010_00064 - 0.014 15.1 0.0 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) TraG-D_C PF12696.7 pAAFJ01000010_00064 - 0.017 15.1 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG RsgA_GTPase PF03193.16 pAAFJ01000010_00064 - 0.056 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF1639 PF07797.14 pAAFJ01000010_00064 - 0.073 13.1 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) TrbI_Ftype PF09677.10 pAAFJ01000010_00065 - 0.028 14.7 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Peptidase_S26 PF10502.9 pAAFJ01000010_00066 - 1.6e-15 57.1 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 PRA-CH PF01502.18 pAAFJ01000010_00066 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase TraH PF06122.11 pAAFJ01000010_00067 - 5.3e-64 216.8 0.3 5.3e-64 216.8 0.3 1.6 2 0 0 2 2 2 1 Conjugative relaxosome accessory transposon protein ArfGap PF01412.18 pAAFJ01000010_00067 - 0.37 10.9 1.7 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf SAYSvFN PF10260.9 pAAFJ01000010_00068 - 0.046 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Ribosomal_L6e PF01159.19 pAAFJ01000010_00068 - 0.84 10.2 6.1 1.7 9.2 5.5 1.9 1 1 0 1 1 1 0 Ribosomal protein L6e TraN PF06986.11 pAAFJ01000010_00069 - 3.3e-26 92.5 26.5 9.2e-25 87.7 20.4 3.0 2 1 0 2 2 2 1 Type-1V conjugative transfer system mating pair stabilisation Lectin_C PF00059.21 pAAFJ01000010_00069 - 1.8e-05 25.4 0.0 1.8e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain Xol-1_GHMP-like PF09109.10 pAAFJ01000010_00069 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like TraF PF13728.6 pAAFJ01000010_00070 - 3.2e-18 66.4 7.8 4.7e-18 65.8 7.8 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein PUA_2 PF14306.6 pAAFJ01000010_00070 - 0.015 15.0 0.3 0.028 14.1 0.3 1.6 1 0 0 1 1 1 0 PUA-like domain DUF2369 PF10179.9 pAAFJ01000010_00070 - 0.18 12.2 2.7 0.79 10.1 0.3 2.4 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2369) TraG_N PF07916.11 pAAFJ01000010_00071 - 3.7e-55 187.6 16.8 3.7e-55 187.6 16.8 1.9 2 1 0 2 2 2 1 TraG-like protein, N-terminal region TIM21 PF08294.11 pAAFJ01000010_00072 - 2.7 7.9 3.9 7.5 6.4 0.4 2.5 2 1 1 3 3 3 0 TIM21 YwiC PF14256.6 pAAFJ01000010_00072 - 2.9 8.2 13.6 0.14 12.5 1.5 2.9 2 1 1 3 3 3 0 YwiC-like protein T_cell_tran_alt PF15128.6 pAAFJ01000010_00072 - 3.6 7.4 10.0 0.69 9.7 2.2 2.8 1 1 2 3 3 3 0 T-cell leukemia translocation-altered Wzy_C PF04932.15 pAAFJ01000010_00073 - 0.086 12.5 0.1 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF4713 PF15831.5 pAAFJ01000010_00073 - 0.17 12.3 3.6 0.18 12.2 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) PFO_beta_C PF12367.8 pAAFJ01000010_00075 - 0.064 13.4 1.6 0.093 12.9 0.2 2.0 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Phage_Treg PF04761.12 pAAFJ01000010_00075 - 0.085 13.0 1.7 0.33 11.1 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator AAA_25 PF13481.6 pAAFJ01000010_00076 - 1.7e-18 66.9 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 pAAFJ01000010_00076 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DnaB_C PF03796.15 pAAFJ01000010_00076 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 pAAFJ01000010_00076 - 0.041 13.2 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 pAAFJ01000010_00076 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 pAAFJ01000010_00076 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.15 pAAFJ01000010_00076 - 0.23 11.4 2.5 1.2 9.1 2.4 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HTH_3 PF01381.22 pAAFJ01000010_00077 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pAAFJ01000010_00077 - 1.2e-05 25.2 0.7 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TACC_C PF05010.14 pAAFJ01000010_00077 - 0.013 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal T3SchapCesA PF11439.8 pAAFJ01000010_00077 - 0.11 12.7 0.4 0.43 10.8 0.1 1.9 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA HTH_31 PF13560.6 pAAFJ01000010_00077 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Toprim_3 PF13362.6 pAAFJ01000010_00078 - 5.2e-09 36.3 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pAAFJ01000010_00078 - 0.017 15.6 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain AAA_25 PF13481.6 pAAFJ01000010_00079 - 1e-15 57.8 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pAAFJ01000010_00079 - 0.0004 19.8 0.0 0.0041 16.5 0.0 2.1 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pAAFJ01000010_00079 - 0.0014 18.3 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pAAFJ01000010_00079 - 0.013 14.8 0.0 0.049 13.0 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA PF00004.29 pAAFJ01000010_00079 - 0.07 13.6 0.1 0.91 10.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pAAFJ01000010_00079 - 0.34 11.0 3.4 2.6 8.1 3.4 2.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SseC PF04888.12 pAAFJ01000010_00080 - 0.0012 18.6 1.4 0.0012 18.6 1.4 1.8 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Leu_Phe_trans PF03588.14 pAAFJ01000010_00080 - 0.034 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase T2SSF PF00482.23 pAAFJ01000010_00080 - 0.18 11.8 0.1 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3185 PF11381.8 pAAFJ01000010_00080 - 0.2 11.7 9.2 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2207 PF09972.9 pAAFJ01000010_00080 - 5.6 5.6 16.6 0.074 11.8 0.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Resolvase PF00239.21 pAAFJ01000010_00081 - 9.9e-36 123.0 0.2 1.4e-35 122.5 0.2 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain Mga PF05043.13 pAAFJ01000010_00081 - 0.012 16.1 2.2 0.15 12.7 0.6 2.5 2 0 0 2 2 2 0 Mga helix-turn-helix domain DUF2790 PF10976.8 pAAFJ01000010_00081 - 0.14 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) TrbC PF04956.13 pAAFJ01000010_00082 - 4.8e-15 55.6 8.1 5.6e-15 55.4 8.1 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family CagE_TrbE_VirB PF03135.14 pAAFJ01000010_00083 - 2.5e-43 148.6 0.5 6.2e-43 147.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pAAFJ01000010_00083 - 1.2e-19 70.3 2.0 2.1e-19 69.5 2.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pAAFJ01000010_00084 - 2.7e-29 101.5 0.0 4.5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) T4SS PF07996.11 pAAFJ01000010_00085 - 2.3e-23 83.6 16.9 2.8e-23 83.4 16.9 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins CHASE4 PF05228.13 pAAFJ01000010_00085 - 0.05 13.8 5.7 1 9.6 0.2 2.9 2 1 1 3 3 3 0 CHASE4 domain KMP11 PF03037.16 pAAFJ01000010_00085 - 0.074 13.8 2.3 0.31 11.8 0.0 2.9 1 1 3 4 4 4 0 Kinetoplastid membrane protein 11 AChE_tetra PF08674.10 pAAFJ01000010_00085 - 0.099 12.4 1.2 0.5 10.1 0.1 2.2 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain zf-RING_6 PF14835.6 pAAFJ01000010_00085 - 0.12 12.2 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Med8 PF10232.9 pAAFJ01000010_00085 - 0.22 11.1 9.0 0.022 14.4 3.9 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PCRF PF03462.18 pAAFJ01000010_00085 - 0.25 11.2 11.7 2.7 7.8 0.4 2.2 2 0 0 2 2 2 0 PCRF domain TrbL PF04610.14 pAAFJ01000010_00086 - 5.9e-33 114.4 25.5 8.1e-33 114.0 25.5 1.3 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein DUF2070 PF09843.9 pAAFJ01000010_00086 - 0.31 9.3 16.7 0.47 8.7 16.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AIM3 PF17096.5 pAAFJ01000010_00086 - 5.4 8.0 7.0 9.6 7.2 7.0 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF412 PF04217.13 pAAFJ01000010_00086 - 6.5 6.7 10.8 20 5.1 6.7 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF412 VirB8 PF04335.13 pAAFJ01000010_00089 - 8.4e-50 169.6 0.1 1e-49 169.3 0.1 1.0 1 0 0 1 1 1 1 VirB8 protein Wzz PF02706.15 pAAFJ01000010_00089 - 2.4 8.5 6.7 2.8 8.3 3.2 2.5 2 1 0 2 2 2 0 Chain length determinant protein CagX PF03524.15 pAAFJ01000010_00090 - 2.3e-53 181.1 0.8 4.6e-53 180.1 0.8 1.5 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pAAFJ01000010_00091 - 1.3e-46 158.8 0.1 1.3e-46 158.8 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein DUF5345 PF17280.2 pAAFJ01000010_00091 - 0.17 11.8 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) MORN_2 PF07661.13 pAAFJ01000010_00092 - 0.39 11.1 2.9 2.8 8.4 0.6 2.8 2 0 0 2 2 2 0 MORN repeat variant Ribosomal_S13 PF00416.22 pAAFJ01000010_00092 - 0.83 10.1 4.2 17 5.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S13/S18 T2SSE PF00437.20 pAAFJ01000010_00093 - 5.1e-54 183.2 0.0 6.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 pAAFJ01000010_00093 - 4.9e-05 23.6 0.0 9.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pAAFJ01000010_00093 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pAAFJ01000010_00093 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pAAFJ01000010_00093 - 0.00062 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 pAAFJ01000010_00093 - 0.0028 18.2 1.3 0.0028 18.2 1.3 1.9 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 pAAFJ01000010_00093 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 pAAFJ01000010_00093 - 0.003 17.0 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_15 PF13175.6 pAAFJ01000010_00093 - 0.0035 17.1 2.5 0.0035 17.1 2.5 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 pAAFJ01000010_00093 - 0.0041 16.9 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 pAAFJ01000010_00093 - 0.0043 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.22 pAAFJ01000010_00093 - 0.012 16.0 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 pAAFJ01000010_00093 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 pAAFJ01000010_00093 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 pAAFJ01000010_00093 - 0.015 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 pAAFJ01000010_00093 - 0.015 15.4 1.0 0.03 14.4 0.2 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 pAAFJ01000010_00093 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 pAAFJ01000010_00093 - 0.021 14.6 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 pAAFJ01000010_00093 - 0.023 14.1 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 pAAFJ01000010_00093 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 pAAFJ01000010_00093 - 0.045 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 pAAFJ01000010_00093 - 0.046 12.6 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 pAAFJ01000010_00093 - 0.051 13.6 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.15 pAAFJ01000010_00093 - 0.055 13.5 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SMC_N PF02463.19 pAAFJ01000010_00093 - 0.063 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 pAAFJ01000010_00093 - 0.07 12.9 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 pAAFJ01000010_00093 - 0.073 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 pAAFJ01000010_00093 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 pAAFJ01000010_00093 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 pAAFJ01000010_00093 - 0.091 12.8 0.3 0.21 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain GvpD PF07088.11 pAAFJ01000010_00093 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 pAAFJ01000010_00093 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 pAAFJ01000010_00093 - 0.12 12.6 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 pAAFJ01000010_00093 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain YscJ_FliF PF01514.17 pAAFJ01000010_00094 - 0.019 14.7 2.6 0.31 10.7 0.1 2.4 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Njmu-R1 PF15053.6 pAAFJ01000010_00094 - 0.028 13.5 1.6 0.051 12.7 1.6 1.4 1 0 0 1 1 1 0 Mjmu-R1-like protein family FtsQ PF03799.15 pAAFJ01000010_00094 - 0.18 12.7 0.8 1.8 9.4 0.0 2.4 3 0 0 3 3 3 0 Cell division protein FtsQ Halogen_Hydrol PF10112.9 pAAFJ01000010_00094 - 1.1 9.2 6.9 4.3 7.3 0.8 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Flagellin_N PF00669.20 pAAFJ01000010_00094 - 2.1 8.5 7.4 1.9 8.6 0.4 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region SlyX PF04102.12 pAAFJ01000010_00094 - 2.2 9.0 7.3 4.6 7.9 0.8 2.6 3 0 0 3 3 2 0 SlyX DUF1664 PF07889.12 pAAFJ01000010_00094 - 2.4 8.2 10.7 3.9 7.5 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 pAAFJ01000010_00094 - 5.7 7.4 10.3 4 7.9 0.5 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 pAAFJ01000010_00094 - 5.9 7.3 7.8 1.6 9.1 0.6 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Vac_Fusion PF02346.16 pAAFJ01000010_00094 - 6 6.6 7.8 1.2 8.8 0.8 2.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 FapA PF03961.13 pAAFJ01000010_00094 - 6.9 5.2 21.5 0.11 11.0 9.9 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A BST2 PF16716.5 pAAFJ01000010_00094 - 6.9 7.3 17.4 1.4 9.6 3.4 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 T4SS-DNA_transf PF02534.14 pAAFJ01000010_00095 - 1.3e-109 367.1 0.0 1.8e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pAAFJ01000010_00095 - 6.2e-27 94.1 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pAAFJ01000010_00095 - 1.4e-18 67.0 0.0 3.3e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain BRI3BP PF14965.6 pAAFJ01000010_00095 - 0.22 11.0 2.3 0.26 10.8 1.2 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Cag12 PF13117.6 pAAFJ01000010_00096 - 1.1e-16 61.2 0.1 1.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 LPAM_2 PF13627.6 pAAFJ01000010_00096 - 0.027 14.3 3.2 0.044 13.6 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF5061 PF16587.5 pAAFJ01000010_00096 - 0.15 12.2 0.1 0.19 11.8 0.1 1.3 1 1 0 1 1 1 0 17 kDa common-antigen outer membrane protein TrbM PF07424.11 pAAFJ01000010_00097 - 6.3e-39 133.4 1.3 8e-39 133.1 1.3 1.1 1 0 0 1 1 1 1 TrbM Latarcin PF10279.9 pAAFJ01000010_00098 - 0.016 15.6 1.6 0.66 10.4 1.6 3.5 1 1 0 1 1 1 0 Latarcin precursor Lipase_GDSL PF00657.22 pAAFJ01000010_00098 - 0.033 14.2 1.1 0.067 13.2 0.9 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase T3SS_basalb_I PF17001.5 pAAFJ01000010_00098 - 0.078 13.6 4.2 1.7 9.3 0.5 2.8 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cor1 PF04803.12 pAAFJ01000010_00098 - 0.15 12.3 22.3 0.15 12.2 6.2 3.3 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1451 PF07295.11 pAAFJ01000010_00098 - 0.25 11.3 8.8 0.2 11.7 2.5 2.5 1 1 2 3 3 3 0 Zinc-ribbon containing domain TipAS PF07739.13 pAAFJ01000010_00098 - 0.36 11.4 6.4 9 6.9 0.2 3.3 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Exonuc_VII_L PF02601.15 pAAFJ01000010_00098 - 0.37 10.3 10.9 0.65 9.5 2.7 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.14 pAAFJ01000010_00098 - 2.8 8.3 16.8 3.5 8.0 3.1 2.8 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Topoisom_bac PF01131.20 pAAFJ01000010_00100 - 4.4e-96 322.4 2.6 5.6e-96 322.1 2.6 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pAAFJ01000010_00100 - 8.4e-12 45.2 0.4 3.4e-11 43.3 0.1 2.3 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pAAFJ01000010_00100 - 1.2e-07 31.3 19.1 0.00081 19.1 3.8 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pAAFJ01000010_00100 - 0.00043 20.5 0.2 0.69 10.2 0.0 2.5 2 0 0 2 2 2 2 zinc-ribbon Zn_ribbon_SprT PF17283.2 pAAFJ01000010_00100 - 0.014 15.3 1.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Toprim_2 PF13155.6 pAAFJ01000010_00100 - 0.036 14.5 0.3 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 Toprim-like HTH_34 PF13601.6 pAAFJ01000010_00100 - 0.074 13.2 0.5 0.77 10.0 0.1 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain Zn-ribbon_8 PF09723.10 pAAFJ01000010_00100 - 0.077 13.1 0.7 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 pAAFJ01000010_00100 - 0.11 12.4 2.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Toprim_4 PF13662.6 pAAFJ01000010_00100 - 0.12 12.8 0.1 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 Toprim domain zf-ribbon_3 PF13248.6 pAAFJ01000010_00100 - 0.18 11.3 1.0 12 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 pAAFJ01000010_00100 - 0.44 10.7 3.7 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS1 PF03811.13 pAAFJ01000010_00100 - 0.46 10.2 3.3 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-HIT PF04438.16 pAAFJ01000010_00100 - 0.48 10.3 4.2 5.9 6.8 0.4 2.6 2 0 0 2 2 2 0 HIT zinc finger zf_C2H2_10 PF18414.1 pAAFJ01000010_00100 - 2.6 7.7 7.4 11 5.7 1.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger PIN_4 PF13638.6 pAAFJ01000010_00100 - 6 7.2 6.6 0.81 10.0 1.0 2.4 3 0 0 3 3 3 0 PIN domain zf-H2C2_2 PF13465.6 pAAFJ01000010_00100 - 8.1 7.1 8.1 12 6.5 0.7 3.2 3 0 0 3 3 2 0 Zinc-finger double domain TetR_C_5 PF08360.11 pAAFJ01000010_00102 - 0.012 15.8 4.6 0.013 15.7 4.6 1.0 1 0 0 1 1 1 0 QacR-like protein, C-terminal region YopX PF09643.10 pAAFJ01000010_00103 - 2.1e-13 50.5 2.2 3.4e-13 49.8 2.2 1.4 1 0 0 1 1 1 1 YopX protein YopX PF09643.10 pAAFJ01000010_00104 - 1.7e-05 24.9 0.1 2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 YopX protein TAFII28 PF04719.14 pAAFJ01000010_00104 - 0.072 13.2 0.0 5.9 7.1 0.0 2.3 1 1 1 2 2 2 0 hTAFII28-like protein conserved region CRISPR_Cas2 PF09827.9 pAAFJ01000010_00106 - 0.00069 19.7 1.5 0.0022 18.1 0.0 2.3 1 1 1 2 2 2 1 CRISPR associated protein Cas2 RRM_1 PF00076.22 pAAFJ01000010_00106 - 0.0021 17.8 0.5 0.0083 15.9 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPD11 PF18824.1 pAAFJ01000010_00106 - 0.086 12.9 1.8 0.17 12.0 0.4 2.2 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 AAA_31 PF13614.6 pAAFJ01000010_00107 - 1.6e-11 44.5 4.7 1.8e-10 41.1 4.7 2.6 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 pAAFJ01000010_00107 - 3e-11 43.1 1.8 3.3e-06 26.6 1.0 3.1 1 1 1 2 2 2 2 ATPase MipZ CbiA PF01656.23 pAAFJ01000010_00107 - 4.3e-09 36.5 0.1 6.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 pAAFJ01000010_00107 - 0.00013 21.3 0.3 0.00081 18.7 0.0 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 pAAFJ01000010_00107 - 0.0012 18.2 0.1 0.91 8.8 0.0 2.1 2 0 0 2 2 2 2 VirC1 protein ABC2_membrane_3 PF12698.7 pAAFJ01000010_00107 - 0.0018 17.4 0.8 0.002 17.3 0.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_24 PF13479.6 pAAFJ01000010_00107 - 0.0038 17.0 1.2 0.0061 16.3 0.1 1.7 2 1 0 2 2 2 1 AAA domain ParA PF10609.9 pAAFJ01000010_00107 - 0.004 16.6 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ATP_bind_1 PF03029.17 pAAFJ01000010_00107 - 0.019 14.8 0.1 0.066 13.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF2139 PF09910.9 pAAFJ01000010_00107 - 0.14 11.3 0.0 0.45 9.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) CBP_BcsQ PF06564.12 pAAFJ01000010_00107 - 0.14 11.6 0.0 0.57 9.6 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_14 PF13173.6 pAAFJ01000010_00107 - 0.25 11.4 7.9 0.05 13.6 1.3 2.6 1 1 2 3 3 3 0 AAA domain SNF2_N PF00176.23 pAAFJ01000010_00109 - 3.6e-15 55.6 0.1 1.1e-14 53.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 pAAFJ01000010_00109 - 1.5e-09 38.2 7.1 2.8e-09 37.3 0.0 4.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 pAAFJ01000010_00109 - 2.6e-08 34.1 3.3 2.6e-08 34.1 3.3 5.4 5 1 0 6 6 6 1 Type III restriction enzyme, res subunit Eco57I PF07669.11 pAAFJ01000010_00109 - 2.1e-06 28.2 1.2 2.6e-05 24.7 0.1 3.7 3 0 0 3 3 3 1 Eco57I restriction-modification methylase DEAD PF00270.29 pAAFJ01000010_00109 - 0.00053 19.8 2.9 0.006 16.4 1.4 3.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase MTS PF05175.14 pAAFJ01000010_00109 - 0.0033 17.0 0.0 0.015 14.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 pAAFJ01000010_00109 - 0.056 13.3 0.0 0.25 11.2 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Fic PF02661.18 pAAFJ01000010_00112 - 0.025 15.5 0.0 0.055 14.4 0.0 1.6 2 0 0 2 2 2 0 Fic/DOC family Adenyl_cycl_N PF12633.7 pAAFJ01000010_00112 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase NT domain CRISPR_Cas2 PF09827.9 pAAFJ01000010_00114 - 1e-05 25.6 2.4 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 CRISPR associated protein Cas2 GIT_CC PF16559.5 pAAFJ01000010_00114 - 0.014 15.2 5.0 0.023 14.6 5.0 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ABC_tran_Xtn PF12848.7 pAAFJ01000010_00114 - 0.014 15.4 2.7 0.024 14.7 2.7 1.4 1 0 0 1 1 1 0 ABC transporter DUF5595 PF18077.1 pAAFJ01000010_00114 - 0.039 14.0 3.6 0.08 13.0 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF1722 PF08349.11 pAAFJ01000010_00114 - 0.047 14.0 2.6 6.2 7.1 2.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1722) NPBW PF15180.6 pAAFJ01000010_00114 - 0.22 11.4 0.6 0.38 10.6 0.6 1.4 1 0 0 1 1 1 0 Neuropeptides B and W EMP24_GP25L PF01105.24 pAAFJ01000010_00114 - 0.6 10.0 5.3 0.97 9.3 1.9 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2600 PF10776.9 pAAFJ01000010_00115 - 0.0034 16.3 0.5 0.0044 15.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2600) DUF2070 PF09843.9 pAAFJ01000010_00115 - 0.0043 15.4 8.7 0.0049 15.2 8.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) COX7a PF02238.15 pAAFJ01000010_00115 - 0.0096 16.3 1.7 0.76 10.2 0.1 2.6 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VII HlyIII PF03006.20 pAAFJ01000010_00115 - 0.013 15.3 7.6 0.015 15.1 7.6 1.0 1 0 0 1 1 1 0 Haemolysin-III related DUF1129 PF06570.11 pAAFJ01000010_00115 - 0.022 14.3 8.0 0.027 13.9 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF1772 PF08592.11 pAAFJ01000010_00115 - 0.027 14.8 3.3 0.033 14.5 2.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2663 PF10864.8 pAAFJ01000010_00115 - 0.076 13.4 14.4 0.53 10.7 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) DUF898 PF05987.13 pAAFJ01000010_00115 - 0.079 12.0 6.5 0.57 9.2 2.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF418 PF04235.12 pAAFJ01000010_00115 - 0.12 12.3 2.2 0.24 11.3 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF418) Zip PF02535.22 pAAFJ01000010_00115 - 0.18 11.0 6.0 1.2 8.3 6.0 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter Nodulin-like PF06813.13 pAAFJ01000010_00115 - 0.21 11.0 7.9 0.077 12.5 3.6 1.8 1 1 1 2 2 2 0 Nodulin-like DUF4293 PF14126.6 pAAFJ01000010_00115 - 0.24 11.7 12.1 0.53 10.5 12.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) FixH PF05751.11 pAAFJ01000010_00115 - 0.38 10.8 4.2 0.41 10.6 0.3 2.7 3 0 0 3 3 3 0 FixH DUF1673 PF07895.11 pAAFJ01000010_00115 - 1.8 8.3 17.6 0.062 13.0 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) GPI2 PF06432.11 pAAFJ01000010_00115 - 2.4 7.6 9.8 0.11 11.9 3.3 1.8 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4131 PF13567.6 pAAFJ01000010_00115 - 3.4 7.3 5.3 0.85 9.3 1.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Tmpp129 PF10272.9 pAAFJ01000010_00115 - 8.7 5.5 9.3 2.5 7.3 5.1 1.8 1 1 1 2 2 2 0 Putative transmembrane protein precursor Relaxase PF03432.14 pAAFJ01000010_00116 - 2e-07 30.9 0.8 2e-07 30.9 0.8 3.0 2 1 1 3 3 3 1 Relaxase/Mobilisation nuclease domain Tektin PF03148.14 pAAFJ01000010_00116 - 0.19 10.5 6.0 0.13 11.0 0.3 2.4 2 0 0 2 2 2 0 Tektin family RHH_7 PF16777.5 pAAFJ01000010_00117 - 0.085 13.3 6.7 0.32 11.4 2.9 2.5 1 1 1 2 2 2 0 Transcriptional regulator, RHH-like, CopG TMEM95 PF15203.6 pAAFJ01000010_00117 - 0.58 9.8 2.7 0.45 10.1 0.5 1.8 2 0 0 2 2 2 0 TMEM95 family pRN1_helical PF13010.6 pAAFJ01000010_00117 - 4.1 7.4 9.5 2.3 8.2 6.5 1.9 1 1 1 2 2 2 0 Primase helical domain EssA PF10661.9 pAAFJ01000010_00118 - 0.2 11.5 8.8 0.18 11.7 7.9 1.3 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA ANAPC4 PF12896.7 pAAFJ01000010_00119 - 0.11 11.9 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Fic PF02661.18 pAAFJ01000017_00001 - 1.7e-17 64.0 0.1 4.6e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family DUF1495 PF07381.11 pAAFJ01000017_00001 - 0.13 12.2 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Toprim_3 PF13362.6 pAAFJ01000017_00002 - 5.2e-09 36.3 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pAAFJ01000017_00002 - 0.017 15.6 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain SSB PF00436.25 pAAFJ01000017_00005 - 1.4e-29 102.2 0.8 2.1e-29 101.6 0.8 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 pAAFJ01000017_00005 - 0.00012 22.0 0.1 0.00017 21.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DD_K PF12121.8 pAAFJ01000017_00006 - 6 7.1 6.5 2.6 8.2 2.2 2.1 2 0 0 2 2 2 0 Dermaseptin DUF1640 PF07798.11 pAAFJ01000017_00008 - 0.0011 19.0 0.7 0.0014 18.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Merozoite_SPAM PF07133.11 pAAFJ01000017_00008 - 0.0095 16.0 4.1 0.012 15.6 4.1 1.1 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) RecT PF03837.14 pAAFJ01000017_00009 - 2.3e-36 125.2 0.1 4e-36 124.4 0.0 1.3 1 1 0 1 1 1 1 RecT family GGA_N-GAT PF18308.1 pAAFJ01000017_00010 - 0.19 11.4 2.8 0.14 11.8 0.7 1.9 2 0 0 2 2 2 0 GGA N-GAT domain DUF2624 PF11116.8 pAAFJ01000017_00015 - 0.041 14.8 0.1 0.084 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DUF4883 PF16224.5 pAAFJ01000017_00015 - 0.075 13.3 2.6 0.094 13.0 2.6 1.1 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) DUF2031 PF09592.10 pAAFJ01000017_00019 - 0.013 15.0 5.3 0.013 15.1 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) RNA_pol_Rpb2_45 PF10385.9 pAAFJ01000017_00019 - 0.1 12.9 0.4 0.13 12.6 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain DUF4830 PF16112.5 pAAFJ01000017_00020 - 0.0075 16.7 0.1 0.0094 16.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4830) ParE_toxin PF05016.15 pAAFJ01000017_00020 - 0.07 13.7 0.0 0.094 13.3 0.0 1.2 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE PDDEXK_1 PF12705.7 pAAFJ01000017_00022 - 1.5e-05 25.0 0.0 2.8e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 pAAFJ01000017_00022 - 4.4e-05 23.6 1.4 4.9e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF83 MapZ_C2 PF18708.1 pAAFJ01000017_00022 - 0.021 15.1 0.1 0.081 13.2 0.0 2.0 2 0 0 2 2 2 0 MapZ extracellular C-terminal domain 2 NERD PF08378.11 pAAFJ01000017_00022 - 0.072 13.6 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 Nuclease-related domain G-gamma PF00631.22 pAAFJ01000017_00023 - 0.045 13.8 0.6 0.11 12.5 0.6 1.7 1 0 0 1 1 1 0 GGL domain UPF0449 PF15136.6 pAAFJ01000017_00023 - 0.15 12.6 1.7 18 5.9 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 YycI PF09648.10 pAAFJ01000017_00024 - 0.011 15.3 0.6 0.011 15.3 0.6 1.1 1 0 0 1 1 1 0 YycH protein Mad3_BUB1_I PF08311.12 pAAFJ01000017_00024 - 0.023 14.7 1.0 0.027 14.5 1.0 1.1 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Rsbr_N PF08678.10 pAAFJ01000017_00024 - 0.049 13.7 0.1 1.2 9.2 0.0 2.0 1 1 1 2 2 2 0 Rsbr N terminal DUF4450 PF14614.6 pAAFL01000016_00001 - 0.0036 16.9 0.7 0.0056 16.3 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4450) VanW PF04294.13 pAAFL01000016_00001 - 0.013 15.2 0.3 0.045 13.4 0.1 1.8 1 1 0 2 2 2 0 VanW like protein SBDS PF01172.18 pAAFL01000016_00001 - 0.089 12.9 4.1 0.17 12.0 2.2 2.3 1 1 1 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Phage_lysozyme PF00959.19 pAAFL01000016_00002 - 1.2e-10 41.7 1.2 2e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Phage lysozyme Vta1 PF04652.16 pAAFL01000016_00002 - 2.6 8.0 10.4 0.056 13.4 0.9 2.9 3 1 1 4 4 4 0 Vta1 like SseC PF04888.12 pAAFL01000016_00004 - 0.0049 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 pAAFL01000016_00004 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pAAFL01000016_00004 - 0.036 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 pAAFL01000016_00004 - 0.061 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UvrA_DNA-bind PF17755.1 pAAFL01000016_00005 - 0.012 15.9 0.3 5.1 7.5 0.1 2.5 2 0 0 2 2 2 0 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 pAAFL01000016_00007 - 0.0051 17.1 0.3 3.2 8.1 0.0 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain Glyco_tranf_2_5 PF13712.6 pAAFL01000016_00008 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 pAAFL01000016_00009 - 3e-39 135.2 20.8 3e-39 135.2 20.8 3.2 3 1 0 3 3 3 1 TraG-like protein, N-terminal region DUF4131 PF13567.6 pAAFL01000016_00010 - 0.0008 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 pAAFL01000016_00010 - 0.015 15.2 3.3 0.019 14.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 pAAFL01000016_00010 - 0.056 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2663 PF10864.8 pAAFL01000016_00010 - 0.13 12.7 2.1 0.16 12.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2721 PF11026.8 pAAFL01000016_00010 - 0.27 11.1 5.3 0.34 10.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) YafQ_toxin PF15738.5 pAAFL01000016_00011 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pAAFL01000016_00013 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HicB_lk_antitox PF15919.5 pAAFL01000016_00015 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pAAFL01000016_00015 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 pAAFL01000016_00016 - 1.8e-06 27.9 0.0 3.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, DUF5309 PF17236.2 pAAFL01000016_00017 - 3e-05 23.5 0.5 3.3e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5309) SGT1 PF07093.11 pAAFL01000016_00019 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 pAAFL01000016_00019 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 pAAFL01000016_00019 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF4795 PF16043.5 pAAFL01000016_00020 - 0.026 14.1 0.1 0.043 13.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3825 PF12873.7 pAAFL01000016_00021 - 1.9e-28 99.6 0.3 3e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) GAGBD PF16828.5 pAAFL01000016_00022 - 0.011 15.8 1.4 0.012 15.7 1.4 1.0 1 0 0 1 1 1 0 GAG-binding domain on surface antigen IMS_C PF11799.8 pAAFL01000016_00025 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 pAAFL01000016_00025 - 0.0002 21.5 0.0 0.00067 19.8 0.1 1.9 2 0 0 2 2 2 1 IMS family HHH motif AAA_25 PF13481.6 pAAFL01000016_00026 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 pAAFL01000016_00026 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 pAAFL01000016_00026 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 pAAFL01000016_00026 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 pAAFL01000016_00026 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 pAAFL01000016_00026 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 pAAFL01000016_00026 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 pAAFL01000016_00026 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 pAAFL01000016_00026 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 pAAFL01000016_00026 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 pAAFL01000016_00026 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 pAAFL01000016_00026 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 pAAFL01000016_00026 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 pAAFL01000016_00026 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 pAAFL01000016_00026 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 pAAFL01000016_00026 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 pAAFL01000016_00026 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobA_MobL PF03389.15 pAAFL01000016_00027 - 3.7e-79 265.5 0.0 1.4e-78 263.6 0.0 1.9 2 0 0 2 2 2 1 MobA/MobL family Spectrin PF00435.21 pAAFL01000016_00027 - 0.015 15.8 2.4 0.18 12.3 0.2 2.9 2 1 0 2 2 2 0 Spectrin repeat Prominin PF05478.11 pAAFL01000016_00027 - 0.02 12.9 1.9 0.029 12.4 1.9 1.2 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.6 pAAFL01000016_00027 - 0.021 15.2 2.0 0.059 13.8 0.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF2408 PF10303.9 pAAFL01000016_00027 - 0.032 14.8 2.4 0.06 13.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 pAAFL01000016_00027 - 0.065 13.5 2.3 6.6 7.1 0.3 3.5 4 0 0 4 4 4 0 Tup N-terminal Mod_r PF07200.13 pAAFL01000016_00027 - 0.65 10.1 8.1 0.62 10.2 0.4 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SOAR PF16533.5 pAAFL01000016_00027 - 1.2 9.1 5.4 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region DUF4407 PF14362.6 pAAFL01000016_00027 - 5.1 6.4 8.4 53 3.0 8.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3847 PF12958.7 pAAFL01000016_00028 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 pAAFL01000016_00028 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 pAAFL01000016_00028 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 pAAFL01000016_00028 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CPT PF07931.12 pAAFL01000016_00029 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 pAAFL01000016_00029 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pAAFL01000016_00029 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pAAFL01000016_00029 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 pAAFL01000016_00029 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.14 pAAFL01000016_00030 - 0.097 11.9 0.0 0.097 11.9 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Ank_3 PF13606.6 pAAFL01000019_00001 - 9.9e-11 40.9 0.3 0.002 18.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 pAAFL01000019_00001 - 1.5e-08 35.1 0.1 1.1e-07 32.3 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 pAAFL01000019_00001 - 4.2e-06 27.2 0.1 0.0016 19.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 pAAFL01000019_00001 - 0.00044 20.6 0.0 15 6.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pAAFL01000019_00001 - 0.066 13.5 0.0 22 5.5 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pAAFL01000019_00002 - 2.8e-07 30.8 0.0 2.8e-07 30.8 0.0 3.5 3 1 1 4 4 4 1 Restriction endonuclease fold toxin 7 VRR_NUC PF08774.11 pAAFL01000019_00002 - 0.027 14.6 0.0 0.093 12.8 0.0 2.0 1 0 0 1 1 1 0 VRR-NUC domain DUF2239 PF09998.9 pAAFL01000019_00002 - 3.7 7.3 8.1 1.6 8.5 0.6 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Ank_3 PF13606.6 pAAFL01000019_00003 - 1.4e-10 40.5 0.2 0.0029 18.0 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 pAAFL01000019_00003 - 8.2e-09 35.9 0.0 5.5e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 pAAFL01000019_00003 - 1.1e-05 25.9 0.1 0.001 19.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 pAAFL01000019_00003 - 5.2e-05 23.5 0.0 1.7 9.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pAAFL01000019_00003 - 0.028 14.8 0.1 1.4 9.4 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Phage_GPD PF05954.11 pAAFL01000019_00004 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 pAAFL01000019_00004 - 0.01 15.7 1.7 0.029 14.2 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Gp5_C PF06715.12 pAAFL01000019_00004 - 0.013 15.6 4.6 0.19 11.9 0.1 4.1 2 1 2 4 4 4 0 Gp5 C-terminal repeat (3 copies) DUF3540 PF12059.8 pAAFL01000019_00004 - 0.1 12.4 0.8 0.45 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) TCL1_MTCP1 PF01840.17 pAAFL01000019_00004 - 0.11 12.2 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pAAFL01000019_00005 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pAAFL01000019_00006 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pAAFL01000019_00007 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pAAFL01000019_00007 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pAAFL01000019_00007 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pAAFL01000019_00008 - 1e-169 564.9 0.0 1.2e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pAAFL01000019_00008 - 0.096 12.7 0.8 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pAAFL01000019_00009 - 1.2e-51 174.6 3.8 1.3e-51 174.4 3.8 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pAAFL01000019_00009 - 0.082 11.5 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pAAFL01000019_00010 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pAAFL01000019_00010 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pAAFL01000019_00010 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 pAAFL01000019_00010 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 pAAFL01000019_00011 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pAAFL01000019_00012 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pAAFL01000019_00013 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pAAFL01000019_00014 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pAAFL01000019_00015 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pAAFL01000019_00015 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pAAFL01000019_00015 - 3.5e-26 92.4 2.0 5.3e-26 91.8 2.0 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pAAFL01000019_00015 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pAAFL01000019_00015 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pAAFL01000019_00015 - 0.0036 16.9 5.2 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pAAFL01000019_00015 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DrrA_P4M PF14860.6 pAAFL01000019_00015 - 0.4 10.6 5.8 0.11 12.3 1.4 2.4 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain FHA PF00498.26 pAAFL01000019_00016 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pAAFL01000019_00016 - 0.0018 18.5 0.0 0.0046 17.3 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pAAFL01000019_00016 - 0.066 13.6 2.7 0.66 10.4 0.7 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain UvrA_DNA-bind PF17755.1 pAAFL01000020_00001 - 0.00041 20.7 0.5 0.19 12.1 0.1 2.3 2 0 0 2 2 2 2 UvrA DNA-binding domain Y1_Tnp PF01797.16 pAAFL01000020_00004 - 1.9e-13 50.5 2.2 2.3e-13 50.3 2.2 1.1 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pAAFL01000020_00005 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pAAFL01000020_00005 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pAAFL01000020_00005 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pAAFL01000020_00005 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pAAFL01000020_00005 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pAAFL01000020_00005 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pAAFL01000020_00005 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pAAFL01000020_00005 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pAAFL01000020_00005 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 pAAFL01000020_00006 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 pAAFL01000020_00006 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 pAAFL01000020_00007 - 1.9e-13 50.5 2.2 2.3e-13 50.3 2.2 1.1 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pAAFL01000020_00008 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pAAFL01000020_00008 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pAAFL01000020_00008 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pAAFL01000020_00008 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pAAFL01000020_00008 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pAAFL01000020_00008 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pAAFL01000020_00008 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pAAFL01000020_00008 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pAAFL01000020_00008 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3492 PF11997.8 pAAFL01000020_00009 - 0.2 11.4 2.9 0.51 10.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CLZ PF16526.5 pAAFL01000020_00009 - 1.1 9.7 4.8 11 6.4 0.2 3.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lipase_3 PF01764.25 pAAFL01000020_00010 - 2.5e-07 30.7 0.0 8.6e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 pAAFL01000020_00010 - 0.00063 19.5 2.0 0.0025 17.6 0.0 2.8 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 pAAFL01000020_00010 - 0.084 13.5 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 pAAFL01000020_00010 - 0.18 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain CitMHS PF03600.16 pAAFL01000020_00011 - 0.022 14.0 0.5 0.025 13.8 0.5 1.1 1 0 0 1 1 1 0 Citrate transporter Ion_trans PF00520.31 pAAFL01000020_00011 - 0.88 8.7 13.1 1.3 8.2 13.1 1.4 1 1 0 1 1 1 0 Ion transport protein DUF3810 PF12725.7 pAAFL01000020_00011 - 1.1 8.6 11.5 1.3 8.3 11.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Spo7 PF03907.13 pAAFL01000020_00011 - 1.9 7.9 6.7 3.1 7.2 6.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DHHC PF01529.20 pAAFL01000020_00011 - 9.4 6.3 11.7 18 5.5 11.7 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3810 PF12725.7 pAAFL01000020_00013 - 0.0022 17.4 5.2 0.0024 17.3 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) CitMHS PF03600.16 pAAFL01000020_00013 - 0.036 13.3 0.3 0.033 13.4 0.3 1.0 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 pAAFL01000020_00013 - 0.2 11.4 5.8 0.29 10.8 5.8 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 pAAFL01000020_00013 - 2.1 7.7 10.6 4.7 6.6 10.2 1.8 1 1 0 1 1 1 0 Spo7-like protein APH PF01636.23 pAAFL01000021_00001 - 3.6e-07 30.4 0.0 3.9e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C15 PF01470.17 pAAFL01000021_00002 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pAAFL01000021_00003 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pAAFL01000021_00003 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pAAFL01000021_00003 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pAAFL01000021_00003 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pAAFL01000021_00003 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pAAFL01000021_00003 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_18 PF13238.6 pAAFL01000021_00004 - 3.4e-14 53.5 0.0 4.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pAAFL01000021_00004 - 5e-10 39.5 0.0 9.9e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pAAFL01000021_00004 - 1.2e-09 38.5 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pAAFL01000021_00004 - 1.5e-08 34.1 0.0 3.2e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 pAAFL01000021_00004 - 2.9e-06 27.6 0.1 1.1e-05 25.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 pAAFL01000021_00004 - 5.6e-06 26.8 0.0 5.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 pAAFL01000021_00004 - 2e-05 24.9 0.0 5.9e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pAAFL01000021_00004 - 5.9e-05 23.1 0.0 8.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 pAAFL01000021_00004 - 0.00012 22.5 0.1 0.00052 20.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pAAFL01000021_00004 - 0.00031 21.2 0.0 0.00043 20.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pAAFL01000021_00004 - 0.0012 18.2 0.2 0.0018 17.6 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 pAAFL01000021_00004 - 0.0017 18.7 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 pAAFL01000021_00004 - 0.0019 17.7 0.0 0.0038 16.7 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 pAAFL01000021_00004 - 0.0023 17.7 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pAAFL01000021_00004 - 0.0029 18.1 0.1 0.003 18.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 pAAFL01000021_00004 - 0.0039 16.9 0.1 0.0042 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 pAAFL01000021_00004 - 0.004 17.1 0.0 0.049 13.5 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase TIP49 PF06068.13 pAAFL01000021_00004 - 0.0061 15.8 0.2 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 pAAFL01000021_00004 - 0.0075 15.6 0.7 0.016 14.6 0.1 1.8 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 pAAFL01000021_00004 - 0.011 14.8 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 pAAFL01000021_00004 - 0.012 15.5 0.5 0.034 14.1 0.2 1.8 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 pAAFL01000021_00004 - 0.017 14.9 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 pAAFL01000021_00004 - 0.018 14.9 0.1 1 9.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 pAAFL01000021_00004 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 pAAFL01000021_00004 - 0.022 14.6 0.0 0.069 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 pAAFL01000021_00004 - 0.022 14.3 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 RuvB_N PF05496.12 pAAFL01000021_00004 - 0.023 14.5 0.1 0.08 12.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MKT1_N PF12247.8 pAAFL01000021_00004 - 0.027 14.8 0.0 0.1 13.0 0.0 2.0 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_25 PF13481.6 pAAFL01000021_00004 - 0.028 14.0 0.1 0.071 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 pAAFL01000021_00004 - 0.039 13.3 0.4 0.084 12.2 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 pAAFL01000021_00004 - 0.04 13.1 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Hydin_ADK PF17213.3 pAAFL01000021_00004 - 0.041 14.2 1.1 0.054 13.8 0.2 1.6 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 pAAFL01000021_00004 - 0.042 13.8 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ArsA_ATPase PF02374.15 pAAFL01000021_00004 - 0.047 12.9 0.1 0.099 11.8 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase Rad17 PF03215.15 pAAFL01000021_00004 - 0.051 13.5 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 pAAFL01000021_00004 - 0.055 13.9 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 pAAFL01000021_00004 - 0.056 13.2 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 pAAFL01000021_00004 - 0.069 12.7 0.5 0.12 11.9 0.0 1.6 2 1 0 2 2 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 pAAFL01000021_00004 - 0.076 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 pAAFL01000021_00004 - 0.096 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase3 PF18751.1 pAAFL01000021_00004 - 0.14 12.0 0.5 0.4 10.6 0.0 1.9 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_3 PF07726.11 pAAFL01000021_00004 - 0.15 11.9 0.1 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PG_binding_3 PF09374.10 pAAFL01000021_00004 - 0.18 12.1 0.4 2.2 8.6 0.0 2.5 2 1 1 3 3 2 0 Predicted Peptidoglycan domain Cytidylate_kin2 PF13189.6 pAAFL01000021_00004 - 0.29 11.2 2.2 16 5.6 0.2 2.3 1 1 0 2 2 2 0 Cytidylate kinase-like family TnpV PF14198.6 pAAFL01000021_00005 - 3.3e-41 139.8 0.5 3.6e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV DUF4368 PF14287.6 pAAFL01000021_00006 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 pAAFL01000021_00006 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.4 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 pAAFL01000021_00006 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 pAAFL01000021_00006 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 pAAFL01000021_00006 - 0.14 12.2 0.7 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Snapin_Pallidin PF14712.6 pAAFL01000021_00006 - 1.2 9.6 6.0 13 6.3 0.2 2.9 3 0 0 3 3 3 0 Snapin/Pallidin IMS PF00817.20 pAAFL01000021_00007 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family HTH_3 PF01381.22 pAAFL01000021_00009 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pAAFL01000021_00009 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pAAFL01000021_00009 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 pAAFL01000021_00009 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pAAFL01000021_00009 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pAAFL01000021_00009 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pAAFL01000021_00009 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pAAFL01000021_00009 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pAAFL01000021_00009 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pAAFL01000021_00009 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pAAFL01000021_00009 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pAAFL01000021_00009 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pAAFL01000021_00009 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 pAAFL01000021_00009 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 pAAFL01000021_00009 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 pAAFL01000021_00009 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 pAAFL01000021_00009 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 pAAFL01000021_00009 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pAAFL01000021_00009 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pAAFL01000021_00009 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 pAAFL01000021_00011 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 pAAFL01000021_00011 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Sigma_reg_N PF13800.6 pAAFL01000021_00012 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CCDC-167 PF15188.6 pAAFL01000021_00013 - 0.002 18.4 0.4 0.0033 17.7 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 pAAFL01000021_00013 - 0.015 15.4 3.5 0.04 14.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) HSBP1 PF06825.12 pAAFL01000021_00013 - 0.033 14.0 0.1 2.2 8.2 0.0 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Streptin-Immun PF11083.8 pAAFL01000021_00013 - 0.052 14.0 0.6 0.2 12.1 0.1 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4164 PF13747.6 pAAFL01000021_00013 - 0.1 12.9 0.4 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Trimer_CC PF08954.11 pAAFL01000021_00013 - 0.14 11.7 0.1 9.8 5.8 0.0 3.0 1 1 1 2 2 2 0 Trimerisation motif YafQ_toxin PF15738.5 pAAFL01000021_00018 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pAAFL01000021_00018 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 pAAFL01000021_00018 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 pAAFL01000021_00018 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system WGR PF05406.15 pAAFL01000021_00023 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pAAFL01000021_00023 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 pAAFL01000021_00024 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 pAAFL01000021_00025 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pAAFL01000021_00025 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pAAFL01000021_00025 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 pAAFL01000021_00025 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 pAAFL01000021_00025 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 pAAFL01000021_00025 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SprT-like PF10263.9 pAAFL01000021_00028 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 pAAFL01000021_00028 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain CtsR_C PF17727.1 pAAFL01000022_00001 - 0.086 13.0 0.1 7.5 6.8 0.0 2.5 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Ribosomal_L44 PF00935.19 pAAFL01000022_00001 - 0.13 12.8 0.6 0.27 11.7 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L44 Flp1_like PF16982.5 pAAFL01000022_00002 - 0.015 14.7 2.9 0.015 14.7 2.9 2.2 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pAAFL01000022_00003 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pAAFL01000022_00003 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pAAFL01000022_00003 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pAAFL01000022_00003 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pAAFL01000022_00003 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pAAFL01000022_00003 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pAAFL01000022_00003 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pAAFL01000022_00004 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pAAFL01000022_00004 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pAAFL01000022_00004 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pAAFL01000022_00004 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pAAFL01000022_00004 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pAAFL01000022_00005 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pAAFL01000022_00005 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pAAFL01000022_00006 - 0.00012 22.0 0.6 0.0016 18.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pAAFL01000022_00006 - 0.0018 18.3 0.9 0.014 15.4 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pAAFL01000022_00006 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pAAFL01000022_00007 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pAAFL01000022_00007 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal SNF2_N PF00176.23 pAAFL01000022_00008 - 2.3e-16 59.5 1.6 4e-16 58.7 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pAAFL01000022_00008 - 8.8e-08 32.3 8.7 8.8e-08 32.3 8.7 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pAAFL01000022_00008 - 8.3e-07 29.3 0.2 4.7e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Eco57I PF07669.11 pAAFL01000022_00008 - 2e-05 25.1 0.7 0.00021 21.8 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase DEAD PF00270.29 pAAFL01000022_00008 - 2e-05 24.4 2.5 0.0014 18.4 0.5 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase BST2 PF16716.5 pAAFL01000022_00008 - 3.6 8.3 6.2 14 6.3 2.7 3.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 GramPos_pilinBB PF16569.5 pAAFL01000022_00009 - 0.017 15.9 4.1 0.19 12.6 1.9 2.3 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain Peptidase_C39 PF03412.15 pAAFL01000022_00012 - 5e-18 65.2 0.0 6.6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pAAFL01000022_00012 - 0.00014 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 pAAFL01000022_00012 - 0.054 14.0 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family Dynamin_N PF00350.23 pAAFL01000022_00014 - 0.032 14.3 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Dynamin family DUF4299 PF14132.6 pAAFL01000023_00002 - 1.4e-08 34.5 0.1 1.6e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) XPG_I PF00867.18 pAAFL01000023_00002 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 pAAFL01000023_00004 - 5.8e-17 61.8 2.0 1.1e-16 60.9 2.0 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pAAFL01000023_00004 - 0.25 11.3 7.2 0.13 12.2 1.5 2.3 2 0 0 2 2 2 0 Ribosome recycling factor Imm59 PF15597.6 pAAFL01000023_00005 - 0.23 12.0 8.7 0.51 10.9 1.8 2.2 1 1 1 2 2 2 0 Immunity protein 59 CobN-Mg_chel PF02514.16 pAAFL01000023_00006 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Ntox24 PF15529.6 pAAFL01000023_00007 - 0.00052 20.3 0.6 0.00084 19.6 0.6 1.4 1 1 0 1 1 1 1 Bacterial toxin 24 AHH PF14412.6 pAAFL01000023_00011 - 1e-15 57.8 1.5 2e-15 56.9 1.5 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Imm70 PF15601.6 pAAFL01000023_00013 - 2.7e-51 172.5 0.6 3e-51 172.4 0.6 1.0 1 0 0 1 1 1 1 Immunity protein 70 Herpes_V23 PF01802.17 pAAFL01000023_00013 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein AbfS_sensor PF18225.1 pAAFL01000023_00014 - 0.067 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain DUF1574 PF07611.11 pAAFL01000023_00015 - 0.023 14.1 2.5 0.027 13.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) LPD7 PF18821.1 pAAFL01000023_00015 - 0.037 14.1 0.4 3.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 pAAFL01000023_00015 - 1.8 9.1 9.9 1.6 9.2 2.8 3.1 1 1 2 3 3 3 0 Immunity protein 59 TNT PF14021.6 pAAFL01000023_00016 - 1.5e-15 57.5 0.0 1.1e-08 35.5 0.0 2.3 2 0 0 2 2 2 2 Tuberculosis necrotizing toxin Ank_3 PF13606.6 pAAFL01000023_00019 - 2.9e-10 39.5 0.1 0.00091 19.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 pAAFL01000023_00019 - 1.5e-09 38.3 0.0 1.1e-08 35.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 pAAFL01000023_00019 - 1.3e-05 25.6 0.1 0.0011 19.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 pAAFL01000023_00019 - 3.6e-05 24.0 0.0 2.5 8.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pAAFL01000023_00019 - 0.0063 16.8 0.3 0.13 12.7 0.0 3.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Rapsyn_N PF10579.9 pAAFL01000025_00002 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region DZR PF12773.7 pAAFL01000025_00003 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 pAAFL01000025_00003 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 pAAFL01000025_00003 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myc-LZ PF02344.15 pAAFL01000025_00004 - 0.045 13.9 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Myc leucine zipper domain DivIC PF04977.15 pAAFL01000025_00005 - 0.0014 18.3 0.2 0.0014 18.3 0.2 4.2 5 0 0 5 5 5 1 Septum formation initiator Prok-TraM PF09228.10 pAAFL01000025_00007 - 0.072 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF2345 PF10106.9 pAAFL01000025_00007 - 0.18 11.7 1.5 1.4 8.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Flu_B_M2 PF04772.12 pAAFL01000025_00007 - 2.2 8.6 11.0 0.18 12.1 0.4 3.0 1 1 2 3 3 3 0 Influenza B matrix protein 2 (BM2) Y1_Tnp PF01797.16 pAAFL01000026_00001 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like PcfJ PF14284.6 pAAFL01000026_00002 - 7.7e-06 25.9 1.5 8.6e-06 25.7 1.5 1.1 1 0 0 1 1 1 1 PcfJ-like protein NmrA PF05368.13 pAAFL01000026_00002 - 0.0093 15.5 0.3 0.012 15.2 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family DUF4060 PF13269.6 pAAFL01000026_00002 - 0.085 12.9 0.1 5.4 7.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4060) GTP_EFTU PF00009.27 pAAFL01000026_00004 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAAFL01000026_00004 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAAFL01000026_00004 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAAFL01000026_00004 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAAFL01000026_00004 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pAAFL01000026_00004 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pAAFL01000026_00004 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pAAFL01000026_00004 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAAFL01000026_00004 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF5442 PF17514.2 pAAFL01000026_00005 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) AAA_31 PF13614.6 pAAFL01000027_00001 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pAAFL01000027_00001 - 0.0021 18.1 0.8 0.019 15.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pAAFL01000027_00001 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Put_DNA-bind_N PF06971.13 pAAFL01000027_00003 - 0.034 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus RseC_MucC PF04246.12 pAAFL01000027_00005 - 9.1 6.3 6.3 2.4 8.1 3.1 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2974 PF11187.8 pAAFL01000027_00007 - 0.00072 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pAAFL01000027_00007 - 0.044 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 pAAFL01000027_00007 - 0.1 12.4 0.2 0.28 11.1 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) DUF2239 PF09998.9 pAAFL01000028_00001 - 0.081 12.7 0.7 0.1 12.4 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) sCache_like PF16736.5 pAAFL01000028_00001 - 0.11 12.6 5.3 0.16 12.0 5.3 1.2 1 0 0 1 1 1 0 Single Cache-like PepSY_2 PF13670.6 pAAFL01000028_00001 - 0.17 11.9 0.9 0.28 11.2 0.9 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ank_3 PF13606.6 pAAFL01000028_00002 - 1.1e-09 37.7 0.3 0.013 16.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 pAAFL01000028_00002 - 4e-08 33.7 0.1 2.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 pAAFL01000028_00002 - 0.00041 20.7 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pAAFL01000028_00002 - 0.0021 18.3 0.1 0.029 14.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 pAAFL01000028_00002 - 0.0029 18.2 0.1 0.18 12.4 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pAAFL01000028_00003 - 6.7e-08 32.7 0.0 6.7e-08 32.7 0.0 3.5 3 1 0 3 3 3 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 pAAFL01000028_00003 - 2.2 8.1 9.1 1.7 8.4 0.6 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Ank_2 PF12796.7 pAAFL01000028_00004 - 4e-12 46.6 0.5 2.9e-07 31.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pAAFL01000028_00004 - 1.4e-10 40.4 0.3 0.0017 18.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 pAAFL01000028_00004 - 1.4e-05 25.3 0.0 0.76 10.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 pAAFL01000028_00004 - 8.4e-05 23.0 0.2 0.018 15.6 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FAM25 PF15825.5 pAAFL01000028_00004 - 0.0056 17.0 1.3 2.4 8.6 0.2 2.6 2 0 0 2 2 2 2 FAM25 family Ank_5 PF13857.6 pAAFL01000028_00004 - 0.095 13.0 0.1 2.7 8.4 0.0 3.3 3 1 1 4 4 4 0 Ankyrin repeats (many copies) AHH PF14412.6 pAAFL01000028_00004 - 0.17 11.9 0.6 23 5.1 0.0 2.5 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Tox-REase-7 PF15649.6 pAAFL01000028_00005 - 1.3e-08 35.0 0.4 2.4e-08 34.2 0.1 1.6 2 0 0 2 2 2 1 Restriction endonuclease fold toxin 7 Tn7_Tnp_TnsA_N PF08722.11 pAAFL01000028_00005 - 0.0021 18.2 1.0 0.0029 17.8 0.1 1.7 2 0 0 2 2 2 1 TnsA endonuclease N terminal VRR_NUC PF08774.11 pAAFL01000028_00005 - 0.041 13.9 0.0 0.13 12.4 0.0 1.8 1 1 1 2 2 2 0 VRR-NUC domain adh_short PF00106.25 pAAFL01000029_00001 - 0.0094 15.4 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Mur_ligase_C PF02875.21 pAAFL01000029_00001 - 0.086 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 pAAFL01000029_00002 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pAAFL01000029_00002 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal PTS-HPr PF00381.19 pAAFL01000029_00003 - 0.17 12.1 0.0 0.19 12.0 0.0 1.0 1 0 0 1 1 1 0 PTS HPr component phosphorylation site NYN PF01936.18 pAAFL01000029_00005 - 1.2e-09 38.8 0.0 1.4e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pAAFL01000029_00005 - 0.014 15.3 0.5 0.028 14.3 0.5 1.6 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family PIN7 PF18475.1 pAAFL01000029_00005 - 0.028 15.1 0.0 0.045 14.4 0.0 1.4 1 0 0 1 1 1 0 PIN domain DUF2400 PF09674.10 pAAFL01000029_00006 - 0.26 11.2 4.0 0.56 10.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) HTH_46 PF15977.5 pAAFL01000030_00002 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pAAFL01000030_00002 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pAAFL01000030_00002 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pAAFL01000030_00002 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pAAFL01000030_00002 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pAAFL01000030_00003 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pAAFL01000030_00003 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pAAFL01000030_00003 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide AAA_25 PF13481.6 pAAFL01000031_00001 - 4.4e-15 55.8 0.0 1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pAAFL01000031_00001 - 0.00028 20.3 0.0 0.0018 17.6 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pAAFL01000031_00001 - 0.0021 17.8 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pAAFL01000031_00001 - 0.007 15.7 0.0 0.07 12.5 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pAAFL01000031_00001 - 0.02 15.3 0.3 0.31 11.5 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ApoC-I PF04691.12 pAAFL01000031_00001 - 0.13 12.2 3.2 4.8 7.2 0.0 3.9 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) CbiA PF01656.23 pAAFL01000031_00001 - 0.21 11.6 2.1 0.89 9.6 2.1 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pAAFL01000031_00001 - 0.65 9.6 5.5 13 5.5 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain DUF1947 PF09183.10 pAAFL01000031_00001 - 0.65 10.3 6.4 1.6 9.1 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) HicA_toxin PF07927.12 pAAFL01000031_00002 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Endomucin PF07010.12 pAAFL01000032_00002 - 0.029 14.4 0.5 0.03 14.3 0.5 1.1 1 0 0 1 1 1 0 Endomucin HicA_toxin PF07927.12 pAAFL01000032_00003 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, N-glycanase_N PF09112.10 pAAFL01000033_00001 - 0.016 15.0 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Phage_terminase PF10668.9 pAAFL01000033_00001 - 0.17 11.9 0.6 0.37 10.9 0.6 1.4 1 0 0 1 1 1 0 Phage terminase small subunit RHH_7 PF16777.5 pAAFL01000033_00002 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pAAFL01000033_00002 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal adh_short PF00106.25 pAAFL01000033_00003 - 0.0094 15.4 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Mur_ligase_C PF02875.21 pAAFL01000033_00003 - 0.086 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain HicB_lk_antitox PF15919.5 pAAFL01000034_00001 - 4.4e-08 33.3 0.0 6.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Toprim_3 PF13362.6 pAAFL01000035_00001 - 1.3e-06 28.7 0.1 4.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pAAFL01000035_00001 - 0.0086 16.3 0.1 0.88 9.9 0.0 2.3 2 0 0 2 2 2 2 Retrotransposon gag protein Acetyltransf_7 PF13508.7 pAANQ01000006_00002 - 0.0008 19.8 0.1 0.002 18.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pAANQ01000006_00002 - 0.021 15.1 0.1 0.051 13.8 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GramPos_pilinBB PF16569.5 pAANQ01000006_00002 - 0.2 12.5 4.3 0.17 12.7 1.7 2.0 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain Relaxase PF03432.14 pAANQ01000006_00003 - 3.6e-10 39.9 7.4 3.6e-10 39.9 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pAANQ01000006_00004 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pAANQ01000006_00004 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pAANQ01000006_00004 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pAANQ01000006_00004 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pAANQ01000006_00004 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pAANQ01000006_00005 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pAANQ01000006_00005 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pAANQ01000006_00005 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pAANQ01000006_00007 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pAANQ01000006_00007 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pAANQ01000006_00007 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pAANQ01000006_00007 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pAANQ01000006_00008 - 0.0069 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pAANQ01000006_00009 - 0.0079 16.2 2.8 0.01 15.8 2.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 pAANQ01000006_00009 - 1.1 9.3 4.2 2 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pAANQ01000006_00011 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pAANQ01000006_00012 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pAANQ01000006_00013 - 1.6e-14 54.0 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pAANQ01000006_00013 - 0.00038 19.9 0.0 0.0019 17.6 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pAANQ01000006_00013 - 0.0022 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pAANQ01000006_00013 - 0.009 15.4 0.0 0.058 12.7 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pAANQ01000006_00013 - 0.0093 16.4 0.2 0.22 11.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pAANQ01000006_00013 - 0.18 11.9 1.8 0.82 9.7 1.8 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pAANQ01000006_00013 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pAANQ01000006_00014 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pAANQ01000006_00014 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pAANQ01000006_00014 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pAANQ01000006_00014 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pAANQ01000006_00015 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pAANQ01000006_00017 - 2.7e-15 56.4 6.5 2.8e-15 56.3 6.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pAANQ01000006_00017 - 0.071 13.0 4.3 0.096 12.5 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pAANQ01000006_00018 - 2.4e-51 174.8 0.3 5.5e-51 173.6 0.3 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pAANQ01000006_00018 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pAANQ01000006_00018 - 0.046 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pAANQ01000006_00019 - 1.8e-31 108.5 0.0 2.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Y_Y_Y PF07495.13 pAANQ01000006_00019 - 0.1 12.6 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PBECR2 PF18810.1 pAANQ01000006_00020 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pAANQ01000006_00021 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pAANQ01000006_00022 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pAANQ01000006_00022 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pAANQ01000006_00022 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pAANQ01000006_00022 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pAANQ01000006_00023 - 1e-28 101.1 13.2 1.4e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pAANQ01000006_00023 - 0.0036 17.4 0.6 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pAANQ01000006_00023 - 0.015 15.9 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain KMP11 PF03037.16 pAANQ01000006_00023 - 0.026 15.3 1.5 0.17 12.7 0.0 3.1 2 2 0 2 2 2 0 Kinetoplastid membrane protein 11 Tissue_fac PF01108.17 pAANQ01000006_00023 - 0.03 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Tissue factor AATF-Che1 PF13339.6 pAANQ01000006_00023 - 0.34 11.6 11.8 0.41 11.3 4.5 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 pAANQ01000006_00024 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pAANQ01000006_00024 - 0.061 13.1 0.9 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pAANQ01000006_00024 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Trep_dent_lipo PF09710.10 pAANQ01000006_00025 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pAANQ01000006_00025 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pAANQ01000006_00025 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pAANQ01000006_00026 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pAANQ01000006_00026 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pAANQ01000006_00027 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pAANQ01000006_00027 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 pAANQ01000006_00027 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pAANQ01000006_00028 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pAANQ01000006_00028 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pAANQ01000006_00029 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pAANQ01000006_00029 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pAANQ01000006_00029 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pAANQ01000006_00029 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pAANQ01000006_00029 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pAANQ01000006_00029 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pAANQ01000006_00029 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pAANQ01000006_00029 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pAANQ01000006_00029 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pAANQ01000006_00029 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pAANQ01000006_00029 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pAANQ01000006_00029 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pAANQ01000006_00029 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pAANQ01000006_00029 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pAANQ01000006_00029 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pAANQ01000006_00029 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pAANQ01000006_00029 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pAANQ01000006_00029 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pAANQ01000006_00029 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pAANQ01000006_00029 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pAANQ01000006_00029 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 pAANQ01000006_00029 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 pAANQ01000006_00029 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pAANQ01000006_00029 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pAANQ01000006_00029 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pAANQ01000006_00029 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pAANQ01000006_00029 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pAANQ01000006_00029 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pAANQ01000006_00029 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 pAANQ01000006_00029 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pAANQ01000006_00029 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pAANQ01000006_00029 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pAANQ01000006_00030 - 1.4e-105 353.8 0.1 1.9e-105 353.4 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pAANQ01000006_00030 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pAANQ01000006_00030 - 6.2e-16 58.3 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 pAANQ01000006_00031 - 1e-16 61.2 0.1 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pAANQ01000006_00031 - 0.062 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pAANQ01000006_00032 - 9.5e-39 132.8 1.2 1.2e-38 132.5 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pAANQ01000006_00033 - 0.02 14.7 1.4 0.033 14.0 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pAANQ01000006_00033 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family TACC_C PF05010.14 pAANQ01000006_00033 - 2.1 8.1 10.2 3.7 7.3 8.3 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 pAANQ01000006_00033 - 4.9 7.3 12.2 4.4 7.4 3.2 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IFT20 PF14931.6 pAANQ01000006_00033 - 5.9 7.1 10.6 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 KH_5 PF13184.6 pAANQ01000006_00034 - 0.003 17.6 0.2 0.0034 17.4 0.2 1.0 1 0 0 1 1 1 1 NusA-like KH domain DUF5526 PF17664.1 pAANQ01000006_00034 - 0.027 14.0 0.2 0.029 13.9 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5526) Redoxin PF08534.10 pAANQ01000006_00035 - 0.029 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 pAANQ01000006_00035 - 0.12 12.6 0.1 0.12 12.6 0.1 2.5 2 1 1 3 3 3 0 Uncharacterized YnfE-like Topoisom_bac PF01131.20 pAANQ01000006_00036 - 3.2e-97 326.1 8.5 4.5e-97 325.7 8.5 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pAANQ01000006_00036 - 4.4e-12 46.1 2.4 7.3e-12 45.4 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pAANQ01000006_00036 - 5.7e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pAANQ01000006_00036 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pAANQ01000006_00036 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pAANQ01000006_00036 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pAANQ01000006_00036 - 0.038 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 pAANQ01000006_00036 - 0.052 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair zf-C2H2_4 PF13894.6 pAANQ01000006_00036 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pAANQ01000006_00036 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pAANQ01000006_00036 - 0.09 13.0 4.5 1 9.6 3.7 2.5 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pAANQ01000006_00036 - 0.43 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pAANQ01000006_00036 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pAANQ01000006_00036 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pAANQ01000006_00036 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pAANQ01000006_00036 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pAANQ01000006_00036 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pAANQ01000006_00037 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pAANQ01000006_00037 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pAANQ01000006_00039 - 1.2e-59 201.1 0.3 1.7e-59 200.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAANQ01000006_00039 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAANQ01000006_00039 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAANQ01000006_00039 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAANQ01000006_00039 - 9.9e-07 28.8 0.1 2.3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pAANQ01000006_00039 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pAANQ01000006_00039 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pAANQ01000006_00039 - 0.02 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAANQ01000006_00039 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pAANQ01000006_00039 - 0.11 12.0 0.2 0.45 10.0 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Papo_T_antigen PF02380.15 pAANQ01000006_00040 - 0.00028 21.0 1.6 0.00035 20.7 1.6 1.4 1 0 0 1 1 1 1 T-antigen specific domain CEBP_ZZ PF16366.5 pAANQ01000006_00040 - 0.022 15.0 2.6 0.03 14.6 2.6 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1272 PF06906.11 pAANQ01000006_00040 - 0.049 13.7 3.8 0.074 13.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pAANQ01000006_00041 - 2.9e-05 24.1 0.4 0.00063 19.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pAANQ01000006_00041 - 0.00046 20.3 0.8 0.0047 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pAANQ01000006_00041 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pAANQ01000006_00041 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 pAANQ01000006_00042 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pAANQ01000006_00042 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal PDDEXK_9 PF08011.11 pAANQ01000006_00043 - 0.017 15.0 0.2 0.032 14.1 0.2 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF5445 PF17520.2 pAANQ01000006_00044 - 1 9.2 12.2 1.3 8.9 11.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5445) Adenyl_transf PF04439.12 pAJ489618_00001 - 6.7e-81 271.5 0.9 7.6e-81 271.3 0.9 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pAJ489618_00002 - 7.8e-21 74.5 0.1 1e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pAJ489618_00002 - 1.4e-13 51.1 0.1 2.4e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pAJ489618_00002 - 2.6e-12 46.8 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pAJ489618_00002 - 3e-10 40.5 1.6 3.6e-10 40.2 1.6 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pAJ489618_00002 - 0.00021 21.4 0.0 0.0004 20.4 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 pAJ489618_00002 - 0.00052 20.7 0.0 0.00064 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 pAJ489618_00002 - 0.0019 18.3 0.0 0.0078 16.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 pAJ489618_00002 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 pAJ489618_00002 - 0.035 13.6 0.2 0.11 12.0 0.2 1.8 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_8 PF13523.6 pAJ489618_00002 - 0.042 13.5 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 pAJ489618_00002 - 0.08 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ APH PF01636.23 pAJ489618_00003 - 4.5e-26 92.2 0.0 5.2e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pAJ489618_00003 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pAJ489618_00003 - 0.0099 15.5 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family HTH_11 PF08279.12 pAJ489618_00004 - 0.00042 20.2 0.1 0.00056 19.8 0.1 1.2 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 pAJ489618_00004 - 0.096 12.3 0.3 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Resolvase PF00239.21 pAJ490186_00001 - 4.3e-18 65.8 0.3 7.1e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain MerR PF00376.23 pAJ490186_00001 - 1.5e-12 47.1 0.0 2.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 pAJ490186_00001 - 6e-11 42.3 0.0 1.7e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 MerR HTH family regulatory protein HTH_17 PF12728.7 pAJ490186_00001 - 0.00043 20.4 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain NTPase_P4 PF11602.8 pAJ490186_00001 - 0.0027 17.0 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 ATPase P4 of dsRNA bacteriophage phi-12 PIN_2 PF10130.9 pAJ490186_00001 - 0.063 13.5 1.4 0.083 13.1 0.4 1.6 2 0 0 2 2 2 0 PIN domain HTH_23 PF13384.6 pAJ490186_00001 - 0.068 13.0 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain OrfB_Zn_ribbon PF07282.11 pAJ490186_00002 - 2.1e-22 78.8 0.9 4.2e-22 77.8 0.9 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pAJ490186_00002 - 2.7e-18 66.4 4.5 2.8e-18 66.3 2.3 2.1 2 1 0 2 2 2 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pAJ490186_00002 - 7.7e-15 54.1 0.3 2.2e-14 52.6 0.3 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Zn_Tnp_IS1595 PF12760.7 pAJ490186_00002 - 0.036 14.0 2.2 0.071 13.1 2.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain APH PF01636.23 pAJ490186_00003 - 5.9e-26 91.8 0.0 6.9e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pAJ490186_00003 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pAJ490186_00003 - 0.018 14.7 0.0 3 7.4 0.0 2.2 1 1 0 2 2 2 0 RIO1 family PRELI PF04707.14 pAVFM02000066_00001 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pAVFM02000066_00001 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pAVFM02000066_00001 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Relaxase PF03432.14 pAVFM02000068_00001 - 2.8e-10 40.2 7.9 2.8e-10 40.2 7.9 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain AdenylateSensor PF16579.5 pAVFM02000068_00001 - 0.15 12.5 7.3 3.7 8.0 0.5 3.3 2 1 0 3 3 3 0 Adenylate sensor of SNF1-like protein kinase Endostatin PF06482.11 pAVFM02000068_00001 - 1.1 8.6 7.0 0.2 11.1 3.1 1.7 1 1 1 2 2 2 0 Collagenase NC10 and Endostatin Helicase_C PF00271.31 pAVFM02000069_00001 - 0.0015 18.9 0.0 0.0015 18.9 0.0 3.0 3 1 1 4 4 4 1 Helicase conserved C-terminal domain efb-c PF12199.8 pAVFM02000069_00002 - 0.05 13.7 0.3 0.07 13.2 0.3 1.3 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Toprim PF01751.22 pAVFM02000070_00001 - 3.2e-13 49.8 0.0 4.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Toprim domain Topoisom_bac PF01131.20 pAVFM02000070_00001 - 0.008 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase EF-hand_8 PF13833.6 pAVFM02000070_00001 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Cys_rich_KTR PF14205.6 pAVFM02000072_00001 - 4.7e-32 109.6 5.1 5.2e-32 109.4 5.1 1.0 1 0 0 1 1 1 1 Cysteine-rich KTR Prim_Zn_Ribbon PF08273.12 pAVFM02000072_00001 - 0.00057 20.1 1.3 0.0023 18.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding domain of primase-helicase zf-ISL3 PF14690.6 pAVFM02000072_00001 - 0.0029 18.2 0.6 0.78 10.5 0.1 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 pAVFM02000072_00001 - 0.0033 17.4 1.7 1.1 9.3 0.1 2.1 1 1 1 2 2 2 2 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 pAVFM02000072_00001 - 0.0038 17.3 1.4 0.87 9.8 0.2 2.2 2 0 0 2 2 2 2 Zinc ribbon domain zf-TFIIB PF13453.6 pAVFM02000072_00001 - 0.0042 16.4 0.8 0.53 9.7 0.1 2.2 2 0 0 2 2 2 1 Transcription factor zinc-finger DNA_ligase_ZBD PF03119.16 pAVFM02000072_00001 - 0.0048 16.9 1.8 0.046 13.7 0.1 2.2 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain NOB1_Zn_bind PF08772.11 pAVFM02000072_00001 - 0.0056 16.8 2.2 0.77 10.0 0.1 2.1 1 1 1 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.6 pAVFM02000072_00001 - 0.01 15.8 1.1 0.51 10.3 0.0 2.6 2 1 1 3 3 3 0 Nudix N-terminal Elf1 PF05129.13 pAVFM02000072_00001 - 0.013 15.6 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-NADH-PPase PF09297.11 pAVFM02000072_00001 - 0.014 15.0 2.0 0.31 10.7 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 pAVFM02000072_00001 - 0.016 15.2 1.0 0.027 14.5 1.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-DNL PF05180.12 pAVFM02000072_00001 - 0.017 15.1 0.6 0.035 14.0 0.6 1.5 1 1 0 1 1 1 0 DNL zinc finger Zn_ribbon_SprT PF17283.2 pAVFM02000072_00001 - 0.024 14.6 2.5 0.041 13.8 2.5 1.4 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DpnI PF06044.12 pAVFM02000072_00001 - 0.033 13.8 0.4 0.042 13.5 0.4 1.1 1 0 0 1 1 1 0 Dam-replacing family zf-C4_Topoisom PF01396.19 pAVFM02000072_00001 - 0.033 14.0 1.9 3.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.6 pAVFM02000072_00001 - 0.042 13.6 3.5 3.5 7.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pAVFM02000072_00001 - 0.046 14.0 2.6 1.3 9.3 0.2 2.1 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain TF_Zn_Ribbon PF08271.12 pAVFM02000072_00001 - 0.07 12.6 3.3 0.68 9.5 3.3 2.2 1 1 0 1 1 1 0 TFIIB zinc-binding HypA PF01155.19 pAVFM02000072_00001 - 0.079 13.0 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pox_E10 PF04805.12 pAVFM02000072_00001 - 0.12 12.2 1.0 5.8 6.9 0.0 2.0 1 1 1 2 2 2 0 E10-like protein conserved region zf-trcl PF13451.6 pAVFM02000072_00001 - 0.13 12.2 3.1 0.74 9.8 2.5 2.0 1 1 0 1 1 1 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 pAVFM02000072_00001 - 0.15 12.5 1.7 9.7 6.8 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.12 pAVFM02000072_00001 - 0.2 12.0 1.9 1.9 8.9 0.1 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_10 PF18414.1 pAVFM02000072_00001 - 0.43 10.2 0.2 0.43 10.2 0.2 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger DUF3797 PF12677.7 pAVFM02000072_00001 - 0.49 10.3 6.6 2.8 7.9 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.6 pAVFM02000072_00001 - 0.64 9.5 5.6 1.8 8.1 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain GTP_EFTU PF00009.27 pAVFM02000072_00002 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAVFM02000072_00002 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAVFM02000072_00002 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAVFM02000072_00002 - 1.3e-12 47.6 0.1 2.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAVFM02000072_00002 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pAVFM02000072_00002 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pAVFM02000072_00002 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pAVFM02000072_00002 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAVFM02000072_00002 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pAVFM02000072_00002 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B TnpV PF14198.6 pAVFM02000072_00003 - 2.8e-43 146.4 0.5 3.2e-43 146.2 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV SNF2_N PF00176.23 pAVFM02000073_00001 - 1.2e-10 40.6 0.2 3.1e-10 39.3 0.2 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 pAVFM02000073_00001 - 6.1e-10 39.4 9.3 1.8e-08 34.5 9.2 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 pAVFM02000073_00001 - 5.8e-07 29.4 0.4 0.0003 20.6 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_11 PF13086.6 pAVFM02000073_00001 - 0.0032 17.3 4.6 1 9.1 3.0 2.3 1 1 1 2 2 2 2 AAA domain Tup_N PF08581.10 pAVFM02000073_00001 - 0.072 13.4 0.3 0.072 13.4 0.3 4.0 4 1 0 4 4 4 0 Tup N-terminal CLZ PF16526.5 pAVFM02000073_00001 - 1.5 9.3 4.7 2.5 8.5 1.4 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1690 PF07956.11 pAVFM02000073_00001 - 1.8 9.0 6.3 2 8.9 0.6 2.7 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Eco57I PF07669.11 pAVFM02000073_00002 - 1.3e-05 25.6 0.2 5.2e-05 23.7 0.2 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 pAVFM02000073_00002 - 0.0038 16.8 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 pAVFM02000073_00003 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pAVFM02000073_00003 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Cag12 PF13117.6 pAVFM02000074_00002 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pAVFM02000074_00002 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pAVFM02000074_00002 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pAVFM02000074_00002 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pAVFM02000074_00003 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pAVFM02000074_00003 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pAVFM02000074_00003 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pAVFM02000074_00003 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pAVFM02000074_00004 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pAVFM02000074_00004 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pAVFM02000074_00004 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pAVFM02000074_00004 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pAVFM02000074_00004 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pAVFM02000074_00004 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pAVFM02000074_00004 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pAVFM02000074_00004 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pAVFM02000074_00004 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pAVFM02000074_00004 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pAVFM02000074_00004 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pAVFM02000074_00004 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pAVFM02000074_00004 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pAVFM02000074_00004 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pAVFM02000074_00004 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pAVFM02000074_00004 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pAVFM02000074_00004 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pAVFM02000074_00004 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pAVFM02000074_00004 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pAVFM02000074_00004 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pAVFM02000074_00004 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pAVFM02000074_00004 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pAVFM02000074_00004 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pAVFM02000074_00004 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pAVFM02000074_00004 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pAVFM02000074_00004 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pAVFM02000074_00004 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pAVFM02000074_00004 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pAVFM02000074_00004 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pAVFM02000074_00004 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pAVFM02000074_00004 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pAVFM02000074_00005 - 1.9e-48 164.8 0.1 3.2e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pAVFM02000074_00005 - 0.022 13.8 0.1 0.032 13.3 0.1 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease HNOBA PF07701.14 pAVFM02000075_00001 - 0.077 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 pAVFM02000075_00001 - 0.081 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like bZIP_1 PF00170.21 pAVFM02000075_00001 - 0.79 9.9 4.9 6.3 7.0 0.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor Phage_pRha PF09669.10 pAVFM02000075_00002 - 1.5e-28 99.2 0.0 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pAVFM02000075_00002 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 pAVFM02000075_00003 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pAVFM02000075_00003 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pAVFM02000075_00003 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pAVFM02000075_00003 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pAVFM02000075_00003 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pAVFM02000075_00003 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pAVFM02000075_00004 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pAVFM02000075_00005 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pAVFM02000075_00005 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pAVFM02000075_00005 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pAVFM02000075_00005 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pAVFM02000075_00006 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pAVFM02000075_00006 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pAVFM02000075_00006 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pAVFM02000075_00006 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pAVFM02000075_00006 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pAVFM02000075_00006 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 pAVFM02000075_00007 - 2.7e-29 102.5 30.5 2.7e-29 102.5 30.5 1.5 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pAVFM02000075_00007 - 0.21 11.4 1.5 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 pAVFM02000075_00008 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pAVFM02000075_00008 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pAVFM02000075_00009 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pAVFM02000075_00009 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pAVFM02000075_00010 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pAVFM02000075_00010 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) SSB PF00436.25 pAVFM02000076_00001 - 1.3e-23 83.0 0.0 1.7e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DnaJ-X PF14308.6 pAVFM02000076_00001 - 0.0027 17.2 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 X-domain of DnaJ-containing Colicin_Ia PF11504.8 pAVFM02000076_00001 - 0.11 12.7 0.1 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Colicin Ia DUF1981 PF09324.10 pAVFM02000076_00001 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) DUF4389 PF14333.6 pAVFM02000076_00002 - 0.054 13.4 3.8 0.08 12.9 3.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4389) DUF2512 PF10710.9 pAVFM02000076_00002 - 0.12 12.1 6.0 0.13 11.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) TctB PF07331.11 pAVFM02000076_00002 - 0.53 10.6 9.7 0.56 10.5 9.7 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family LptF_LptG PF03739.14 pAVFM02000076_00002 - 7.6 5.3 10.9 8.3 5.1 10.9 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1129 PF06570.11 pAVFM02000076_00002 - 7.9 5.9 8.5 9 5.7 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4407 PF14362.6 pAVFM02000076_00002 - 8.6 5.6 8.5 10 5.4 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MgtE_N PF03448.17 pAVFM02000077_00001 - 4e-05 24.2 0.3 0.039 14.6 0.3 2.1 1 1 1 2 2 2 2 MgtE intracellular N domain Com_YlbF PF06133.11 pAVFM02000077_00001 - 0.0099 16.5 1.9 0.0099 16.5 1.9 1.5 2 0 0 2 2 2 1 Control of competence regulator ComK, YlbF/YmcA CpXC PF14353.6 pAVFM02000077_00002 - 0.033 14.2 2.2 0.041 13.9 2.2 1.3 1 1 0 1 1 1 0 CpXC protein A2L_zn_ribbon PF08792.10 pAVFM02000077_00002 - 0.71 9.7 5.5 2.7 7.8 0.6 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain T4SS PF07996.11 pAVFM02000078_00001 - 3.4e-07 30.9 8.7 3.4e-07 30.9 8.7 2.4 1 1 1 2 2 2 1 Type IV secretion system proteins HBM PF16591.5 pAVFM02000078_00001 - 0.0086 15.5 15.0 0.015 14.7 0.2 2.3 2 0 0 2 2 2 1 Helical bimodular sensor domain HTH_16 PF12645.7 pAVFM02000078_00001 - 0.053 13.6 0.4 0.79 9.8 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain NYD-SP28_assoc PF14775.6 pAVFM02000078_00001 - 0.14 12.2 5.9 0.84 9.8 0.5 3.5 2 1 1 3 3 3 0 Sperm tail C-terminal domain GCN5L1 PF06320.13 pAVFM02000078_00001 - 0.48 10.6 0.1 0.48 10.6 0.1 3.4 2 1 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF2937 PF11157.8 pAVFM02000078_00001 - 4.9 6.9 8.7 14 5.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) FlxA PF14282.6 pAVFM02000078_00001 - 7.4 6.6 29.5 5.1 7.1 4.7 4.3 2 1 2 4 4 4 0 FlxA-like protein FIVAR PF07554.13 pAVFM02000078_00002 - 0.034 14.9 8.8 0.056 14.2 8.8 1.3 1 1 0 1 1 1 0 FIVAR domain PRD PF00874.20 pAVFM02000078_00002 - 0.077 13.3 4.1 0.096 13.0 4.1 1.1 1 0 0 1 1 1 0 PRD domain T4SS-DNA_transf PF02534.14 pAVFM02000079_00001 - 3e-58 197.8 2.6 1.2e-57 195.8 2.6 1.7 1 1 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TrwB_AAD_bind PF10412.9 pAVFM02000079_00001 - 4.2e-19 68.7 0.0 2.4e-14 53.1 0.0 2.1 1 1 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 pAVFM02000079_00001 - 3e-14 53.1 0.0 2.4e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 TraM recognition site of TraD and TraG DUF418 PF04235.12 pAVFM02000079_00001 - 0.057 13.4 1.4 0.091 12.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF418) VirB8 PF04335.13 pAVFM02000080_00001 - 3.6e-29 102.1 0.9 4.2e-29 101.9 0.9 1.0 1 0 0 1 1 1 1 VirB8 protein TrwB_AAD_bind PF10412.9 pAVFM02000080_00003 - 6.4e-05 22.0 0.0 7.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain CNTF PF01110.17 pAVFM02000080_00003 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor YsaB PF13983.6 pAVFM02000081_00001 - 0.11 12.8 0.1 0.42 10.9 0.2 1.8 2 0 0 2 2 2 0 YsaB-like lipoprotein CagX PF03524.15 pAVFM02000082_00001 - 9.1e-26 90.9 0.7 1e-25 90.7 0.7 1.0 1 0 0 1 1 1 1 Conjugal transfer protein DUF4905 PF16248.5 pAVFM02000082_00001 - 0.055 13.4 0.1 0.2 11.6 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) Phosphodiest PF01663.22 pAVFM02000082_00001 - 0.076 12.6 1.3 0.25 10.9 1.1 1.7 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase ETRAMP PF09716.10 pAVFM02000082_00002 - 1.5 9.0 8.9 0.36 10.9 1.5 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TrbI PF03743.14 pAVFM02000082_00003 - 8.1e-32 110.6 0.7 1.1e-31 110.2 0.7 1.1 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein TrbI PF03743.14 pAVFM02000082_00004 - 1.8e-06 27.9 0.1 1.9e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein TraH_2 PF06871.11 pAVFM02000082_00004 - 0.06 13.0 0.2 5.2 6.6 0.0 1.9 1 1 1 2 2 2 0 TraH_2 FOXP-CC PF16159.5 pAVFM02000082_00005 - 0.0033 18.0 0.3 0.0038 17.8 0.3 1.2 1 0 0 1 1 1 1 FOXP coiled-coil domain MCR_C PF04609.12 pAVFM02000082_00005 - 0.23 10.5 4.5 0.25 10.4 4.5 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Allexi_40kDa PF05549.11 pAVFM02000082_00005 - 0.66 9.4 4.9 0.64 9.5 4.9 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Aida_N PF08910.10 pAVFM02000082_00005 - 0.68 10.4 5.2 0.71 10.3 5.2 1.1 1 0 0 1 1 1 0 Aida N-terminus TrbL PF04610.14 pAVFM02000084_00002 - 1.5e-31 109.9 22.6 1.5e-31 109.9 22.6 2.2 3 0 0 3 3 3 1 TrbL/VirB6 plasmid conjugal transfer protein Topoisom_bac PF01131.20 pAVFM02000084_00003 - 2.2e-13 50.0 0.0 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pAVFM02000084_00003 - 4.4e-10 39.7 0.3 9.2e-10 38.7 0.2 1.5 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 pAVFM02000084_00003 - 0.1 13.1 0.0 0.29 11.6 0.0 1.8 2 1 0 2 2 2 0 Toprim domain DUF2852 PF11014.8 pAVFM02000085_00002 - 0.0052 16.9 1.5 0.0052 16.9 1.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2852) DUF5442 PF17514.2 pAVFM02000085_00002 - 0.026 14.7 5.3 0.026 14.7 5.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Stn1_C PF12659.7 pAVFM02000085_00002 - 0.1 12.6 3.0 0.25 11.3 3.0 1.8 1 1 0 1 1 1 0 Telomere capping C-terminal wHTH DUF1856 PF08983.10 pAVFM02000085_00002 - 0.53 10.6 4.2 7.3 6.9 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1856) NifT PF06988.11 pAVFM02000085_00002 - 7.3 6.5 6.9 3.1 7.6 0.3 3.0 2 1 1 3 3 3 0 NifT/FixU protein Toprim_2 PF13155.6 pAVFM02000085_00004 - 2.6e-13 50.2 0.9 2e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 pAVFM02000085_00004 - 0.00012 22.3 0.1 0.00032 21.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3991) Sushi_2 PF09014.10 pAVFM02000085_00004 - 0.056 13.3 0.6 0.091 12.7 0.1 1.6 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Toprim_3 PF13362.6 pAVFM02000085_00004 - 0.067 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Toprim domain Toprim_4 PF13662.6 pAVFM02000085_00004 - 0.071 13.6 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 Toprim domain Toprim PF01751.22 pAVFM02000085_00004 - 0.09 13.0 1.2 0.15 12.3 0.5 1.7 1 1 1 2 2 2 0 Toprim domain Osmo_CC PF08946.10 pAVFM02000085_00004 - 0.26 11.6 0.1 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil VirB8 PF04335.13 pAY190284_00001 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pAY190284_00001 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pAY190285_00001 - 2.8e-55 187.3 1.9 4.6e-55 186.6 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pAY190286_00001 - 5.8e-30 104.5 0.0 6.6e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pAY190286_00001 - 0.0049 16.0 0.1 0.0062 15.7 0.1 1.1 1 0 0 1 1 1 1 HaeIII restriction endonuclease T2SSE PF00437.20 pAY190287_00001 - 6.4e-54 182.8 0.0 7.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pAY190287_00001 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pAY190287_00001 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pAY190287_00001 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pAY190287_00001 - 0.0014 18.9 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pAY190287_00001 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pAY190287_00001 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pAY190287_00001 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pAY190287_00001 - 0.0049 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pAY190287_00001 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pAY190287_00001 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pAY190287_00001 - 0.0088 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pAY190287_00001 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pAY190287_00001 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pAY190287_00001 - 0.022 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pAY190287_00001 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pAY190287_00001 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pAY190287_00001 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pAY190287_00001 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pAY190287_00001 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pAY190287_00001 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pAY190287_00001 - 0.039 13.2 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pAY190287_00001 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pAY190287_00001 - 0.063 11.9 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pAY190287_00001 - 0.065 13.6 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pAY190287_00001 - 0.085 12.8 0.4 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pAY190287_00001 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pAY190287_00001 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pAY190287_00001 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pAY190287_00001 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pAY190287_00001 - 0.29 11.6 3.1 0.32 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain Phage_pRha PF09669.10 pAY190288_00001 - 1.8e-23 82.9 0.1 5.3e-23 81.4 0.1 1.8 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) GTP_EFTU PF00009.27 pAY190525_00001 - 9e-59 198.3 0.3 1.2e-58 197.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAY190525_00001 - 2.6e-23 82.1 0.0 9.7e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAY190525_00001 - 1.1e-16 60.6 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAY190525_00001 - 1.3e-12 47.6 0.1 2.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAY190525_00001 - 1e-06 28.8 0.1 2.4e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pAY190525_00001 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pAY190525_00001 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pAY190525_00001 - 0.021 14.1 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAY190525_00001 - 0.043 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 pAY394560_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAY394560_00001 - 3.7e-23 81.6 0.0 9.7e-23 80.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAY394560_00001 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAY394560_00001 - 1.3e-13 50.8 0.1 2.8e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAY394560_00001 - 1.3e-06 28.5 0.2 4.6e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RF3_C PF16658.5 pAY394560_00001 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 pAY394560_00001 - 0.012 16.0 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Septin PF00735.18 pAY394560_00001 - 0.02 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAY394560_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pAY394560_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pAY394560_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pAY394560_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pAY394560_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 pAY394560_00005 - 0.019 15.1 0.2 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pAY394560_00006 - 0.0057 16.0 1.4 0.0057 16.0 1.4 2.0 3 0 0 3 3 3 1 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 pAY394560_00006 - 1.9 7.5 5.4 2.3 7.2 5.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LysE PF01810.18 pAY394560_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pAY394560_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pAY394560_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pAY394560_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pAY394560_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pAY394560_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pAY394560_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pAY394560_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pAY394560_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pAY394560_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pAY394560_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pAY394560_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pAY394560_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pAY394560_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pAY394560_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pAY394560_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pAY394560_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pAY394560_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pAY394560_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pAY394560_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pAY394560_00012 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pAY394560_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pAY394560_00012 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pAY394560_00012 - 9.2e-06 25.5 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pAY394560_00012 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pAY394560_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pAY394560_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pAY394560_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pAY394560_00014 - 0.00022 21.6 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pAY394560_00014 - 0.0032 17.7 0.0 0.0079 16.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pAY394560_00014 - 0.0091 16.0 0.3 0.017 15.2 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 pAY394560_00015 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pAY394560_00016 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pAY394560_00016 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pAY394560_00016 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pAY394560_00016 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pAY394560_00016 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pAY394560_00017 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pAY394560_00017 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pAY394560_00017 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pAY394560_00019 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pAY394560_00019 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pAY394560_00019 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pAY394560_00019 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pAY394560_00020 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pAY394560_00021 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pAY394560_00021 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pAY394560_00021 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pAY394560_00023 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pAY394560_00024 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pAY394560_00025 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pAY394560_00025 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pAY394560_00025 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pAY394560_00025 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pAY394560_00025 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pAY394560_00025 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pAY394560_00025 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pAY394560_00026 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pAY394560_00026 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pAY394560_00026 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pAY394560_00026 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pAY394560_00027 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.8 1 1 1 2 2 2 2 CRISPR associated protein Cas2 TrbC PF04956.13 pAY394560_00029 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pAY394560_00029 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pAY394560_00030 - 7.1e-51 173.2 0.4 1.6e-50 172.1 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pAY394560_00030 - 2.6e-21 75.7 1.0 4.4e-21 74.9 1.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pAY394560_00030 - 0.046 13.2 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pAY394560_00031 - 1.8e-31 108.5 0.0 2.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Y_Y_Y PF07495.13 pAY394560_00031 - 0.1 12.6 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PBECR2 PF18810.1 pAY394560_00032 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pAY394560_00033 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pAY394560_00034 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pAY394560_00034 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pAY394560_00034 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pAY394560_00034 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pAY394560_00035 - 1e-28 101.1 13.2 1.4e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pAY394560_00035 - 0.0082 16.3 2.4 0.021 15.0 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pAY394560_00035 - 0.016 15.9 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain KMP11 PF03037.16 pAY394560_00035 - 0.02 15.7 0.1 0.17 12.7 0.0 2.6 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 AATF-Che1 PF13339.6 pAY394560_00035 - 0.023 15.3 12.3 0.028 15.1 5.0 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Tissue_fac PF01108.17 pAY394560_00035 - 0.029 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Tissue factor Allexi_40kDa PF05549.11 pAY394560_00035 - 1.2 8.6 6.3 1.2 8.6 2.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pAY394560_00036 - 1.4e-29 103.5 34.4 1.4e-29 103.5 34.4 1.7 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pAY394560_00036 - 0.097 12.5 1.3 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 pAY394560_00037 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pAY394560_00037 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pAY394560_00037 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pAY394560_00038 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pAY394560_00038 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pAY394560_00039 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pAY394560_00039 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 pAY394560_00039 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pAY394560_00040 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pAY394560_00040 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pAY394560_00041 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pAY394560_00041 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pAY394560_00041 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pAY394560_00041 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pAY394560_00041 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pAY394560_00041 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pAY394560_00041 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pAY394560_00041 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pAY394560_00041 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pAY394560_00041 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pAY394560_00041 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pAY394560_00041 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pAY394560_00041 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pAY394560_00041 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pAY394560_00041 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pAY394560_00041 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pAY394560_00041 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pAY394560_00041 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pAY394560_00041 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pAY394560_00041 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pAY394560_00041 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 pAY394560_00041 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 pAY394560_00041 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pAY394560_00041 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pAY394560_00041 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pAY394560_00041 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pAY394560_00041 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pAY394560_00041 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pAY394560_00041 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 pAY394560_00041 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pAY394560_00041 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pAY394560_00041 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pAY394560_00042 - 1.4e-105 353.8 0.1 1.9e-105 353.4 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pAY394560_00042 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pAY394560_00042 - 6.2e-16 58.3 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 pAY394560_00043 - 1e-16 61.2 0.1 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pAY394560_00043 - 0.062 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pAY394560_00044 - 9.5e-39 132.8 1.2 1.2e-38 132.5 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pAY394560_00045 - 0.028 14.2 2.2 0.033 14.0 0.3 2.0 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pAY394560_00045 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family TACC_C PF05010.14 pAY394560_00045 - 2.3 8.0 10.0 3.6 7.3 7.9 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 pAY394560_00045 - 4.6 7.4 12.1 50 4.0 9.2 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT20 PF14931.6 pAY394560_00045 - 5.4 7.2 10.4 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CdhD PF03599.16 pAY394560_00047 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 pAY394560_00047 - 0.028 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 pAY394560_00047 - 0.12 12.6 0.1 0.12 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized YnfE-like Topoisom_bac PF01131.20 pAY394560_00048 - 2.7e-97 326.4 7.4 3.8e-97 325.9 7.4 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pAY394560_00048 - 7.1e-12 45.5 2.2 1.4e-11 44.5 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pAY394560_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pAY394560_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pAY394560_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pAY394560_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pAY394560_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pAY394560_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pAY394560_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pAY394560_00048 - 0.096 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 pAY394560_00048 - 0.1 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pAY394560_00048 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pAY394560_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pAY394560_00048 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pAY394560_00048 - 0.74 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pAY394560_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pAY394560_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pAY394560_00049 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pAY394560_00049 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pAY394561_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAY394561_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAY394561_00001 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAY394561_00001 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAY394561_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pAY394561_00001 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pAY394561_00001 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pAY394561_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAY394561_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pAY394561_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pAY394561_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pAY394561_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pAY394561_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pAY394561_00005 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pAY394561_00005 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pAY394561_00006 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pAY394561_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pAY394561_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pAY394561_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pAY394561_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pAY394561_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pAY394561_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pAY394561_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pAY394561_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pAY394561_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pAY394561_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pAY394561_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pAY394561_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pAY394561_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pAY394561_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pAY394561_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pAY394561_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pAY394561_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pAY394561_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pAY394561_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pAY394561_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pAY394561_00012 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pAY394561_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pAY394561_00012 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pAY394561_00012 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pAY394561_00012 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pAY394561_00013 - 0.0008 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pAY394561_00013 - 0.033 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pAY394561_00014 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pAY394561_00015 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pAY394561_00015 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pAY394561_00015 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pAY394561_00015 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pAY394561_00015 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pAY394561_00016 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pAY394561_00016 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pAY394561_00016 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pAY394561_00018 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pAY394561_00019 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pAY394561_00019 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pAY394561_00019 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pAY394561_00019 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pAY394561_00020 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pAY394561_00021 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pAY394561_00021 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pAY394561_00021 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pAY394561_00021 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pAY394561_00022 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pAY394561_00022 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pAY394561_00022 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pAY394561_00024 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pAY394561_00025 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pAY394561_00026 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pAY394561_00026 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pAY394561_00026 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pAY394561_00026 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pAY394561_00026 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pAY394561_00026 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pAY394561_00026 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pAY394561_00027 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pAY394561_00027 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pAY394561_00027 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pAY394561_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pAY394561_00028 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pAY394561_00028 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pAY394561_00030 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pAY394561_00030 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pAY394561_00031 - 4.8e-50 170.5 0.5 1.1e-49 169.4 0.5 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pAY394561_00031 - 6.8e-21 74.3 1.2 1.2e-20 73.5 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pAY394561_00031 - 0.045 13.2 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pAY394561_00033 - 1.5e-21 76.7 0.1 2.6e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pAY394561_00034 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pAY394561_00034 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pAY394561_00034 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pAY394561_00034 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pAY394561_00034 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pAY394561_00034 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pAY394561_00035 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pAY394561_00036 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pAY394561_00036 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pAY394561_00037 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pAY394561_00037 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pAY394561_00037 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pAY394561_00037 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 pAY394561_00037 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 pAY394561_00037 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pAY394561_00037 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pAY394561_00038 - 1.4e-31 110.0 32.1 1.9e-31 109.5 32.1 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Trep_dent_lipo PF09710.10 pAY394561_00039 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pAY394561_00039 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pAY394561_00040 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pAY394561_00040 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pAY394561_00041 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pAY394561_00041 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pAY394561_00042 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pAY394561_00042 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pAY394561_00043 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pAY394561_00043 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pAY394561_00043 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pAY394561_00043 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pAY394561_00043 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pAY394561_00043 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pAY394561_00043 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pAY394561_00043 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pAY394561_00043 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pAY394561_00043 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pAY394561_00043 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pAY394561_00043 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pAY394561_00043 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pAY394561_00043 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pAY394561_00043 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pAY394561_00043 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pAY394561_00043 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pAY394561_00043 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pAY394561_00043 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pAY394561_00043 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pAY394561_00043 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pAY394561_00043 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pAY394561_00043 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pAY394561_00043 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pAY394561_00043 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pAY394561_00043 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pAY394561_00043 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pAY394561_00043 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pAY394561_00043 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pAY394561_00043 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pAY394561_00043 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pAY394561_00044 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pAY394561_00044 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pAY394561_00044 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pAY394561_00044 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pAY394561_00045 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pAY394561_00045 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pAY394561_00045 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pAY394561_00045 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pAY394561_00046 - 5.7e-29 101.1 0.5 6.4e-29 100.9 0.5 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pAY394561_00047 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pAY394561_00047 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pAY394561_00047 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pAY394561_00049 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pAY394561_00050 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pAY394561_00050 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pAY394561_00050 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pAY394561_00050 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pAY394561_00050 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pAY394561_00050 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pAY394561_00050 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pAY394561_00050 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pAY394561_00050 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pAY394561_00050 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pAY394561_00050 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pAY394561_00050 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pAY394561_00050 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pAY394561_00050 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pAY394561_00050 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pAY394561_00050 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pAY394561_00050 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pAY394561_00051 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pAY394561_00051 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Adenyl_transf PF04439.12 pAY701528_00002 - 1.2e-115 385.5 6.3 1.3e-115 385.3 6.3 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase PcfJ PF14284.6 pAY701528_00003 - 2.9e-05 24.0 2.2 2.9e-05 24.0 2.2 1.6 2 0 0 2 2 2 1 PcfJ-like protein Intein_splicing PF14890.6 pAY701528_00003 - 0.0053 16.7 3.0 0.015 15.3 3.0 1.9 1 1 0 1 1 1 1 Intein splicing domain GTP_EFTU PF00009.27 pAY701528_00005 - 8.9e-59 198.3 0.3 1.2e-58 197.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAY701528_00005 - 2.6e-23 82.1 0.0 9.7e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAY701528_00005 - 8.5e-17 61.0 0.0 2.4e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAY701528_00005 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAY701528_00005 - 9.7e-07 28.9 0.1 2.4e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pAY701528_00005 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pAY701528_00005 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pAY701528_00005 - 0.021 14.1 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAY701528_00005 - 0.043 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF4111 PF13427.6 pAY701528_00007 - 2.6e-26 91.8 0.0 1.1e-25 89.7 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pAY701528_00007 - 1.1e-09 38.2 0.0 5.4e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pAY701528_00007 - 3e-06 27.4 0.0 6.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pAY701528_00007 - 0.00019 21.4 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain MdcG PF10620.9 pAY701528_00007 - 0.2 11.4 0.1 0.67 9.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG AAA_18 PF13238.6 pAY701528_00008 - 4.8e-14 53.0 0.0 6.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pAY701528_00008 - 2.4e-10 40.8 0.0 2.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pAY701528_00008 - 7.5e-10 38.9 0.0 1.4e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 pAY701528_00008 - 1.5e-07 30.9 0.0 3.6e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pAY701528_00008 - 1.1e-05 25.8 0.1 7.7e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 pAY701528_00008 - 2.1e-05 25.0 0.0 3.7e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 pAY701528_00008 - 0.00017 21.9 0.0 0.0004 20.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 pAY701528_00008 - 0.00023 21.4 0.0 0.00099 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pAY701528_00008 - 0.0008 19.4 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pAY701528_00008 - 0.0023 17.7 0.1 0.0057 16.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pAY701528_00008 - 0.0023 18.3 0.0 0.0042 17.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 pAY701528_00008 - 0.0028 18.1 0.2 0.0032 18.0 0.2 1.5 1 1 0 1 1 1 1 ABC transporter KTI12 PF08433.10 pAY701528_00008 - 0.0044 16.5 0.1 0.0092 15.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 pAY701528_00008 - 0.0046 17.4 0.0 0.0056 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pAY701528_00008 - 0.0048 16.2 0.4 0.0056 16.0 0.4 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 pAY701528_00008 - 0.0076 16.2 0.4 2.2 8.2 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 pAY701528_00008 - 0.0079 16.1 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase Rad17 PF03215.15 pAY701528_00008 - 0.0086 16.0 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain T2SSE PF00437.20 pAY701528_00008 - 0.0086 15.2 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 pAY701528_00008 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pAY701528_00008 - 0.0098 15.3 1.3 0.017 14.5 0.1 1.9 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 pAY701528_00008 - 0.0099 15.6 0.8 0.014 15.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pAY701528_00008 - 0.011 15.3 0.1 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 SRP54 PF00448.22 pAY701528_00008 - 0.014 15.1 0.2 0.031 13.9 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DnaB_C PF03796.15 pAY701528_00008 - 0.016 14.6 0.6 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 pAY701528_00008 - 0.021 14.8 0.6 0.049 13.5 0.3 1.7 2 0 0 2 2 2 0 NTPase TIP49 PF06068.13 pAY701528_00008 - 0.034 13.3 0.3 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 pAY701528_00008 - 0.038 13.7 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain dNK PF01712.19 pAY701528_00008 - 0.039 13.8 0.2 0.94 9.3 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 pAY701528_00008 - 0.055 13.6 1.9 2.5 8.2 0.1 2.2 1 1 1 2 2 2 0 Cytidylate kinase-like family PhoH PF02562.16 pAY701528_00008 - 0.065 12.7 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 pAY701528_00008 - 0.067 13.0 1.4 0.12 12.1 1.4 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 pAY701528_00008 - 0.082 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 pAY701528_00008 - 0.084 12.4 0.2 0.5 9.9 0.1 2.2 3 0 0 3 3 3 0 AAA domain MKT1_N PF12247.8 pAY701528_00008 - 0.088 13.2 0.0 0.27 11.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication ATP-synt_ab PF00006.25 pAY701528_00008 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 pAY701528_00008 - 0.12 12.3 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 pAY701528_00008 - 0.14 11.7 0.3 0.28 10.7 0.1 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region CoaE PF01121.20 pAY701528_00008 - 0.16 11.7 0.9 9.3 5.9 0.1 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase Hydin_ADK PF17213.3 pAY701528_00008 - 0.28 11.4 1.0 0.4 10.9 0.2 1.6 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain DpnD-PcfM PF14207.6 pAY701528_00008 - 2.7 8.0 4.9 14 5.7 0.3 2.9 3 0 0 3 3 3 0 DpnD/PcfM-like protein APH PF01636.23 pAY701528_00009 - 1.2e-15 58.1 0.0 7.6e-15 55.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pAY701528_00009 - 1.8e-09 37.5 5.3 3.4e-09 36.6 4.7 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 pAY701528_00009 - 0.00022 20.7 0.7 0.00022 20.7 0.7 2.1 2 1 1 3 3 3 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 pAY701528_00009 - 0.023 13.9 0.6 0.05 12.8 0.3 1.7 2 0 0 2 2 2 0 Fructosamine kinase Ribosomal_S13 PF00416.22 pAY701528_00009 - 0.029 14.8 1.8 0.076 13.4 0.1 2.4 2 1 0 3 3 3 0 Ribosomal protein S13/S18 YppF PF14178.6 pAY701528_00009 - 0.37 10.7 4.0 1.1 9.2 0.1 2.9 1 1 1 2 2 2 0 YppF-like protein ABC2_membrane_3 PF12698.7 pAY701528_00009 - 0.69 9.0 6.6 0.22 10.6 0.9 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein BLOC1_2 PF10046.9 pAY701528_00009 - 3.3 8.1 9.1 1.1 9.6 0.3 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4111 PF13427.6 pAY701528_00010 - 1.6e-23 82.9 0.0 5.6e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4111) NTP_transf_2 PF01909.23 pAY701528_00010 - 1.2e-06 28.7 0.6 2.4e-06 27.7 0.5 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 pAY701528_00010 - 0.00032 20.7 0.1 0.00088 19.3 0.1 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Adenyl_cycl_N PF12633.7 pAY701528_00010 - 0.022 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase NT domain Acetyltransf_1 PF00583.25 pAY701528_00011 - 9e-17 61.4 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 pAY701528_00011 - 1.4e-09 38.0 0.0 1.8e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 pAY701528_00011 - 4.8e-08 33.3 0.1 7.8e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 pAY701528_00011 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 pAY701528_00011 - 0.0045 17.1 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 pAY701528_00011 - 0.007 17.0 0.0 0.0082 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 pAY701528_00011 - 0.034 13.8 0.0 0.04 13.6 0.0 1.3 1 1 0 1 1 1 0 MOZ/SAS family APH PF01636.23 pAY701528_00012 - 2.3e-23 83.4 0.0 3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pAY701528_00012 - 0.0019 17.8 1.2 0.0046 16.6 1.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase 120_Rick_ant PF12574.8 pAY701528_00012 - 0.12 11.5 2.5 1.3 8.2 0.4 2.3 1 1 1 2 2 2 0 120 KDa Rickettsia surface antigen HTH_23 PF13384.6 pAY701528_00013 - 0.0036 17.1 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 pAY701528_00013 - 0.046 13.9 0.7 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pAY701528_00013 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 pAY701528_00013 - 0.097 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 pAY701528_00013 - 0.12 12.4 0.1 0.31 11.0 0.1 1.8 1 1 0 1 1 1 0 HTH domain HU-CCDC81_euk_2 PF18289.1 pAY701528_00013 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HTH_Tnp_ISL3 PF13542.6 pAY701528_00013 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HxlR PF01638.17 pAY701528_00014 - 2.7e-22 78.4 0.0 3.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 pAY701528_00014 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 pAY701528_00014 - 0.00023 21.1 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 pAY701528_00014 - 0.00035 20.4 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 pAY701528_00014 - 0.00061 19.6 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 MarR family PadR PF03551.14 pAY701528_00014 - 0.0015 18.5 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 pAY701528_00014 - 0.0064 16.6 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF1495 PF07381.11 pAY701528_00014 - 0.12 12.2 0.0 0.42 10.5 0.0 1.7 1 1 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) Replic_Relax PF13814.6 pAY701528_00014 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation Putative_PNPOx PF01243.20 pAY701528_00015 - 4.3e-12 46.0 0.0 6.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 pAY701528_00015 - 3.7e-06 26.6 0.0 4.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Pyridox_ox_2 PF12900.7 pAY701528_00015 - 0.063 13.3 0.0 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase IstB_IS21 PF01695.17 pAY701528_00016 - 1.2e-58 197.8 1.9 3.6e-58 196.2 0.2 1.9 1 1 1 2 2 2 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 pAY701528_00016 - 1.3e-08 35.0 0.6 1.3e-08 35.0 0.6 1.6 2 0 0 2 2 2 1 Bacterial dnaA protein RNA_helicase PF00910.22 pAY701528_00016 - 1.7e-05 25.1 0.4 0.00047 20.5 0.0 2.3 2 0 0 2 2 2 1 RNA helicase PhoH PF02562.16 pAY701528_00016 - 3.5e-05 23.4 0.0 8.2e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 pAY701528_00016 - 5.3e-05 23.5 0.2 0.029 14.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 pAY701528_00016 - 6.8e-05 23.3 0.1 0.00012 22.5 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 pAY701528_00016 - 7.7e-05 22.5 0.1 0.0051 16.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 pAY701528_00016 - 8.1e-05 23.1 0.0 0.00015 22.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 pAY701528_00016 - 0.00047 20.2 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 pAY701528_00016 - 0.00062 19.5 0.7 0.0016 18.2 0.7 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 pAY701528_00016 - 0.00073 19.6 0.3 0.00073 19.6 0.3 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 pAY701528_00016 - 0.00099 18.7 0.1 0.0027 17.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AFG1_ATPase PF03969.16 pAY701528_00016 - 0.0026 16.7 0.1 0.0036 16.2 0.1 1.2 1 0 0 1 1 1 1 AFG1-like ATPase NTPase_1 PF03266.15 pAY701528_00016 - 0.0033 17.4 1.3 0.14 12.1 0.1 2.4 1 1 1 2 2 2 1 NTPase NACHT PF05729.12 pAY701528_00016 - 0.0033 17.4 0.2 0.014 15.4 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 pAY701528_00016 - 0.0075 15.9 0.3 0.077 12.6 0.0 2.5 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 pAY701528_00016 - 0.014 15.4 0.1 0.045 13.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 pAY701528_00016 - 0.016 15.1 1.3 0.037 13.9 0.0 2.1 2 1 1 3 3 2 0 RsgA GTPase Roc PF08477.13 pAY701528_00016 - 0.032 14.5 0.0 0.088 13.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 pAY701528_00016 - 0.045 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 pAY701528_00016 - 0.072 12.8 0.2 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 pAY701528_00016 - 0.1 12.2 0.1 0.83 9.3 0.0 2.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 pAY701528_00016 - 0.13 12.2 0.1 0.3 11.1 0.1 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 pAY701528_00016 - 0.15 12.1 3.1 0.17 11.8 2.4 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit rve PF00665.26 pAY701528_00017 - 1.7e-13 50.8 0.0 3.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Phage_portal PF04860.12 pAY701528_00017 - 0.0087 15.3 0.8 0.18 11.0 0.0 2.2 1 1 1 2 2 2 2 Phage portal protein DDE_Tnp_IS1595 PF12762.7 pAY701528_00018 - 3.8e-15 56.2 1.0 6.5e-15 55.5 1.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain Zn_Tnp_IS1595 PF12760.7 pAY701528_00018 - 1.2e-06 28.4 1.3 3e-06 27.1 1.3 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 pAY701528_00018 - 0.0007 19.3 6.9 0.0007 19.3 6.9 1.9 2 0 0 2 2 2 1 InsA N-terminal domain HTH_30 PF13556.6 pAY701528_00018 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 pAY701528_00018 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain PhnJ PF06007.11 pAY701528_00018 - 0.061 12.3 0.1 0.12 11.3 0.1 1.4 1 1 0 1 1 1 0 Phosphonate metabolism protein PhnJ Lar_restr_allev PF14354.6 pAY701528_00018 - 0.062 13.7 3.3 0.063 13.7 1.9 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 pAY701528_00018 - 0.063 13.4 0.7 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 pAY701528_00018 - 0.069 12.9 8.5 0.54 10.0 0.2 2.7 3 0 0 3 3 2 0 A2L zinc ribbon domain zf-C2H2 PF00096.26 pAY701528_00018 - 0.22 12.0 0.2 0.22 12.0 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADK_lid PF05191.14 pAY701528_00018 - 0.25 11.4 4.0 1.8 8.6 0.1 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.6 pAY701528_00018 - 0.73 9.8 8.7 5.6 7.0 8.7 2.2 1 1 0 1 1 1 0 Nudix N-terminal DUF3268 PF11672.8 pAY701528_00018 - 0.82 10.0 5.1 17 5.8 3.0 2.5 2 1 0 2 2 2 0 zinc-finger-containing domain TF_Zn_Ribbon PF08271.12 pAY701528_00018 - 5.5 6.6 7.1 53 3.4 6.8 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding AAA_18 PF13238.6 pAY701528_00019 - 1.9e-14 54.3 0.0 2.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pAY701528_00019 - 3.6e-10 40.2 0.0 5.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pAY701528_00019 - 1.6e-09 37.9 0.0 3.1e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 pAY701528_00019 - 1.6e-09 37.3 0.1 3.3e-09 36.3 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 pAY701528_00019 - 7.3e-06 26.3 0.3 3.1e-05 24.3 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 pAY701528_00019 - 1.1e-05 25.9 0.0 4.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 pAY701528_00019 - 1.8e-05 25.0 0.0 7.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pAY701528_00019 - 5.3e-05 23.7 0.1 0.00021 21.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pAY701528_00019 - 0.00029 21.3 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pAY701528_00019 - 0.0011 18.3 0.2 0.0013 18.0 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 pAY701528_00019 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 pAY701528_00019 - 0.0015 18.9 0.2 0.0032 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 pAY701528_00019 - 0.0018 17.8 0.1 0.0044 16.5 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 pAY701528_00019 - 0.0021 17.8 0.1 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pAY701528_00019 - 0.0043 17.6 0.0 0.0046 17.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.13 pAY701528_00019 - 0.0046 16.2 0.3 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain T2SSE PF00437.20 pAY701528_00019 - 0.0056 15.8 0.0 0.0086 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 pAY701528_00019 - 0.0071 16.1 0.1 0.0082 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 pAY701528_00019 - 0.0082 15.5 0.7 0.018 14.4 0.1 1.8 2 0 0 2 2 2 1 KaiC APS_kinase PF01583.20 pAY701528_00019 - 0.0099 15.8 0.0 0.073 13.0 0.0 2.0 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 pAY701528_00019 - 0.013 15.1 0.1 0.034 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 pAY701528_00019 - 0.014 15.3 1.2 0.027 14.4 0.2 1.8 2 0 0 2 2 2 0 NTPase DnaB_C PF03796.15 pAY701528_00019 - 0.017 14.5 0.7 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 pAY701528_00019 - 0.017 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 pAY701528_00019 - 0.023 14.5 0.0 0.066 12.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 pAY701528_00019 - 0.024 14.4 1.4 0.066 13.0 1.4 1.8 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 pAY701528_00019 - 0.025 14.9 0.2 0.025 14.9 0.2 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_7 PF12775.7 pAY701528_00019 - 0.025 14.1 0.6 0.1 12.1 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 pAY701528_00019 - 0.027 14.2 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArsA_ATPase PF02374.15 pAY701528_00019 - 0.035 13.3 0.1 0.088 12.0 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase NACHT PF05729.12 pAY701528_00019 - 0.035 14.0 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 pAY701528_00019 - 0.041 13.6 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 pAY701528_00019 - 0.043 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain MKT1_N PF12247.8 pAY701528_00019 - 0.044 14.2 0.0 0.099 13.0 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication NB-ARC PF00931.22 pAY701528_00019 - 0.047 12.9 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 pAY701528_00019 - 0.059 13.3 0.1 3.8 7.4 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 pAY701528_00019 - 0.067 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PG_binding_3 PF09374.10 pAY701528_00019 - 0.071 13.4 0.1 1.1 9.5 0.0 2.4 2 1 1 3 3 2 0 Predicted Peptidoglycan domain IPT PF01745.16 pAY701528_00019 - 0.077 12.4 0.2 0.25 10.7 0.1 1.8 2 0 0 2 2 2 0 Isopentenyl transferase PhoH PF02562.16 pAY701528_00019 - 0.086 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 pAY701528_00019 - 0.088 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 pAY701528_00019 - 0.094 12.4 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.11 pAY701528_00019 - 0.1 12.5 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 pAY701528_00019 - 0.11 12.4 0.6 0.38 10.6 0.0 2.1 2 1 1 3 3 3 0 P-loop Nucleotide Kinase3 APH PF01636.23 pAY701528_00020 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pAY701528_00020 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pAY701528_00020 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pAY701528_00020 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pAY701528_00020 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pAY701528_00020 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pAY701528_00021 - 4.2e-51 174.0 0.1 4.8e-51 173.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pAY701528_00022 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pAY701528_00023 - 5.6e-20 71.7 0.1 7.6e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pAY701528_00023 - 1.7e-13 50.8 0.1 2.7e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pAY701528_00023 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pAY701528_00023 - 2e-09 37.8 1.3 2.4e-09 37.5 1.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pAY701528_00023 - 0.0015 19.2 0.0 0.0019 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pAY701528_00023 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pAY701528_00023 - 0.011 15.8 0.0 0.044 13.9 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 pAY701528_00023 - 0.031 14.0 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 pAY701528_00023 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pAY701528_00024 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pAY701528_00024 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pAY701528_00024 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Y1_Tnp PF01797.16 pAY701528_00025 - 1.5e-37 128.4 1.5 2e-37 128.0 1.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pAY701528_00026 - 4.6e-23 80.9 0.3 9.6e-23 79.9 0.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pAY701528_00026 - 6.7e-13 48.9 2.3 6.7e-13 48.9 2.3 2.0 2 1 0 2 2 2 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pAY701528_00026 - 3.3e-09 36.1 2.5 7.3e-09 35.0 2.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4428 PF14471.6 pAY701528_00026 - 0.012 15.6 0.4 0.045 13.7 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prok-RING_1 PF14446.6 pAY701528_00026 - 0.018 15.0 0.5 0.032 14.1 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Methyltr_RsmF_N PF17125.5 pAY701528_00026 - 0.051 14.1 2.4 0.098 13.2 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Rpr2 PF04032.16 pAY701528_00026 - 0.064 13.5 4.2 6.7 7.1 0.2 3.3 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 pAY701528_00026 - 0.11 12.7 1.0 0.29 11.3 1.0 1.8 1 1 0 1 1 1 0 Zinc ribbon domain C1_2 PF03107.16 pAY701528_00026 - 0.13 12.6 1.1 0.25 11.7 1.1 1.5 1 0 0 1 1 1 0 C1 domain Zn_Tnp_IS1595 PF12760.7 pAY701528_00026 - 0.14 12.2 1.0 0.26 11.3 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 pAY701528_00026 - 0.2 11.4 2.0 11 5.9 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 pAY701528_00026 - 0.3 11.1 4.1 11 6.1 0.2 2.7 2 0 0 2 2 2 0 YhfH-like protein Rubredoxin_2 PF18073.1 pAY701528_00026 - 0.53 10.1 1.7 3.2 7.6 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain A2L_zn_ribbon PF08792.10 pAY701528_00026 - 1.2 8.9 5.1 6.4 6.6 5.1 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain AMIN PF11741.8 pAY701528_00026 - 1.9 8.7 8.2 0.89 9.7 0.3 2.9 2 1 0 2 2 2 0 AMIN domain eIF-5_eIF-2B PF01873.17 pAY701528_00026 - 2.6 7.9 7.7 1.1 9.2 1.5 3.0 2 1 0 2 2 2 0 Domain found in IF2B/IF5 NPA PF16469.5 pAY701528_00027 - 0.057 14.0 6.1 0.06 13.9 6.1 1.0 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF1272 PF06906.11 pAY701528_00028 - 0.0094 16.0 4.2 0.016 15.3 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Papo_T_antigen PF02380.15 pAY701528_00028 - 0.011 15.8 6.4 0.017 15.2 6.4 1.4 1 1 0 1 1 1 0 T-antigen specific domain AAA_31 PF13614.6 pAY701528_00029 - 7.9e-05 22.7 0.1 7.9e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 pAY701528_00029 - 0.0032 17.5 0.0 0.0033 17.5 0.0 1.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 pAY701528_00029 - 0.037 13.5 0.1 0.038 13.4 0.1 1.0 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Cas_DxTHG PF09455.10 pAY701528_00030 - 0.045 13.3 3.0 0.075 12.6 1.7 1.8 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family adh_short PF00106.25 pAY701528_00030 - 0.071 12.6 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pAY701528_00030 - 0.078 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Glycos_transf_2 PF00535.26 pAY701528_00030 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Eco57I PF07669.11 pAY701528_00032 - 1.9e-05 25.1 0.2 5.9e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 pAY701528_00032 - 0.0027 17.3 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Acetyltransf_7 PF13508.7 pAY714214_00002 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pAY714214_00002 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pAY714214_00003 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pAY714214_00004 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pAY714214_00004 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pAY714214_00004 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pAY714214_00004 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pAY714214_00004 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pAY714214_00005 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pAY714214_00005 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pAY714214_00005 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pAY714214_00007 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pAY714214_00008 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pAY714214_00008 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pAY714214_00008 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pAY714214_00008 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pAY714214_00009 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pAY714214_00010 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pAY714214_00010 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pAY714214_00010 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pAY714214_00010 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pAY714214_00011 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pAY714214_00011 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pAY714214_00011 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pAY714214_00013 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pAY714214_00014 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pAY714214_00015 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pAY714214_00015 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pAY714214_00015 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pAY714214_00015 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pAY714214_00015 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pAY714214_00015 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pAY714214_00015 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pAY714214_00016 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pAY714214_00016 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pAY714214_00016 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pAY714214_00016 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pAY714214_00017 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pAY714214_00017 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pAY714214_00019 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pAY714214_00019 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pAY714214_00020 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pAY714214_00020 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pAY714214_00020 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pAY714214_00021 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pAY714214_00022 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pAY714214_00022 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pAY714214_00022 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pAY714214_00022 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pAY714214_00022 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pAY714214_00022 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pAY714214_00023 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pAY714214_00024 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pAY714214_00024 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pAY714214_00025 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pAY714214_00025 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pAY714214_00025 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pAY714214_00025 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 pAY714214_00025 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 pAY714214_00025 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pAY714214_00025 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pAY714214_00026 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pAY714214_00026 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pAY714214_00026 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pAY714214_00027 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pAY714214_00027 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pAY714214_00028 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pAY714214_00028 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pAY714214_00029 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pAY714214_00029 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pAY714214_00030 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pAY714214_00030 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pAY714214_00031 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pAY714214_00031 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pAY714214_00031 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pAY714214_00031 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pAY714214_00031 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pAY714214_00031 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pAY714214_00031 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pAY714214_00031 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pAY714214_00031 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pAY714214_00031 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pAY714214_00031 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pAY714214_00031 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pAY714214_00031 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pAY714214_00031 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pAY714214_00031 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pAY714214_00031 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pAY714214_00031 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pAY714214_00031 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pAY714214_00031 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pAY714214_00031 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pAY714214_00031 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pAY714214_00031 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pAY714214_00031 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pAY714214_00031 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pAY714214_00031 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pAY714214_00031 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pAY714214_00031 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pAY714214_00031 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pAY714214_00031 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pAY714214_00031 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pAY714214_00031 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pAY714214_00032 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pAY714214_00032 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pAY714214_00032 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pAY714214_00032 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pAY714214_00033 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pAY714214_00033 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pAY714214_00033 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pAY714214_00033 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pAY714214_00034 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pAY714214_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pAY714214_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pAY714214_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pAY714214_00037 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pAY714214_00038 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pAY714214_00038 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pAY714214_00038 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pAY714214_00038 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pAY714214_00038 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pAY714214_00038 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pAY714214_00038 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pAY714214_00038 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pAY714214_00038 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pAY714214_00038 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pAY714214_00038 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pAY714214_00038 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pAY714214_00038 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pAY714214_00038 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pAY714214_00038 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pAY714214_00038 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pAY714214_00038 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pAY714214_00039 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pAY714214_00039 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pAY714214_00041 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pAY714214_00041 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pAY714214_00041 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pAY714214_00041 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pAY714214_00041 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pAY714214_00041 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pAY714214_00041 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pAY714214_00041 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pAY714214_00041 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pAY714214_00041 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pAY714214_00042 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pAY714214_00044 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pAY714214_00044 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 pAY714214_00045 - 0.039 14.1 0.2 4.3 7.5 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pAY714214_00046 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DUF1516 PF07457.11 pAY714214_00047 - 0.0042 17.3 0.4 0.0049 17.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) LysE PF01810.18 pAY714214_00047 - 0.0049 16.4 0.1 0.0057 16.1 0.1 1.1 1 0 0 1 1 1 1 LysE type translocator DUF2873 PF11395.8 pAY714214_00047 - 1 9.3 0.1 1 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2873) S1_2 PF13509.6 pAY714214_00048 - 0.093 12.8 0.5 0.85 9.7 0.1 2.0 1 1 1 2 2 2 0 S1 domain DUF4044 PF13253.6 pAY714214_00049 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pAY714214_00049 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pAY714214_00049 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pAY714214_00049 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pAY714214_00049 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pAY714214_00050 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pAY714214_00050 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pAY714214_00051 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pAY714214_00051 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pAY714214_00051 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pAY714214_00051 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pAY714214_00051 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pAY714214_00052 - 5.4e-07 29.9 1.0 5.9e-07 29.8 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG PDDEXK_9 PF08011.11 pAY714214_00053 - 0.017 15.0 0.2 0.032 14.1 0.2 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF5445 PF17520.2 pAY714214_00054 - 1 9.2 12.2 1.3 8.9 11.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5445) DUF2362 PF10154.9 pAY730722_00001 - 0.00027 20.0 30.9 0.00027 20.0 30.9 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2362) ORC4_C PF14629.6 pAY730722_00001 - 0.0033 16.8 1.8 0.0033 16.8 1.8 2.2 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 4 C-terminus ApoO PF09769.9 pAY730722_00001 - 1.4 8.9 14.2 9.7 6.2 2.4 4.4 3 2 1 4 4 4 0 Apolipoprotein O DUF2362 PF10154.9 pAY730723_00001 - 0.00027 20.0 30.9 0.00027 20.0 30.9 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2362) ORC4_C PF14629.6 pAY730723_00001 - 0.0033 16.8 1.8 0.0033 16.8 1.8 2.2 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 4 C-terminus ApoO PF09769.9 pAY730723_00001 - 1.4 8.9 14.2 9.7 6.2 2.4 4.4 3 2 1 4 4 4 0 Apolipoprotein O LysE PF01810.18 pCM007863_00001 - 5.6e-05 22.7 0.0 6.7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCM007863_00001 - 0.002 18.3 0.3 0.0021 18.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) TerC PF03741.16 pCM007863_00001 - 0.041 13.6 0.3 0.047 13.4 0.3 1.0 1 0 0 1 1 1 0 Integral membrane protein TerC family DUF5305 PF17231.2 pCM007863_00001 - 0.077 12.4 0.6 0.1 12.0 0.2 1.4 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Saf_2TM PF18303.1 pCM007863_00001 - 0.11 12.1 0.8 0.13 11.8 0.3 1.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain PetL PF05115.14 pCM007863_00001 - 3.4 7.7 9.7 4 7.5 1.2 2.5 2 1 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Flp1_like PF16982.5 pCM007863_00002 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 pCM007863_00002 - 0.26 10.8 3.9 0.28 10.7 3.5 1.3 1 1 0 1 1 1 0 Negative regulator of p53/TP53 YopX PF09643.10 pCM007863_00004 - 1.9e-14 53.8 7.2 4.7e-13 49.3 7.2 2.2 1 1 0 1 1 1 1 YopX protein RE_ApaLI PF09499.10 pCM007863_00004 - 0.0081 15.9 0.6 0.0083 15.9 0.6 1.2 1 0 0 1 1 1 1 ApaLI-like restriction endonuclease DUF2583 PF10762.9 pCM007863_00006 - 0.67 10.4 3.8 15 6.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Topoisom_bac PF01131.20 pCM007863_00009 - 3.9e-97 325.9 7.9 5.4e-97 325.4 7.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCM007863_00009 - 1.9e-12 47.3 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCM007863_00009 - 1.6e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCM007863_00009 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCM007863_00009 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCM007863_00009 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pCM007863_00009 - 0.055 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCM007863_00009 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCM007863_00009 - 0.089 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCM007863_00009 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCM007863_00009 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCM007863_00009 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCM007863_00009 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCM007863_00009 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCM007863_00009 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCM007863_00009 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pCM007863_00010 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCM007863_00012 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCM007863_00012 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCM007863_00012 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCM007863_00013 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCM007863_00014 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCM007863_00014 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCM007863_00014 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCM007863_00014 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCM007863_00015 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCM007863_00015 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCM007863_00015 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCM007863_00015 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pCM007863_00016 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCM007863_00016 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCM007863_00016 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCM007863_00016 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCM007863_00016 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCM007863_00016 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCM007863_00016 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCM007863_00016 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCM007863_00016 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCM007863_00016 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCM007863_00016 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCM007863_00016 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCM007863_00016 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCM007863_00016 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCM007863_00016 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCM007863_00016 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCM007863_00016 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCM007863_00016 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCM007863_00016 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCM007863_00016 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCM007863_00016 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCM007863_00016 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCM007863_00016 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCM007863_00016 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCM007863_00016 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCM007863_00016 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCM007863_00016 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCM007863_00016 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCM007863_00016 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCM007863_00016 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCM007863_00016 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCM007863_00017 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCM007863_00017 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCM007863_00018 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCM007863_00018 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCM007863_00019 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCM007863_00019 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCM007863_00020 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCM007863_00020 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCM007863_00021 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCM007863_00021 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCM007863_00021 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pCM007863_00022 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCM007863_00022 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCM007863_00022 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCM007863_00022 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCM007863_00022 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCM007863_00022 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pCM007863_00022 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pCM007863_00022 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pCM007863_00023 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCM007863_00023 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCM007863_00023 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCM007863_00023 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCM007863_00024 - 1.5e-25 89.2 0.1 1.8e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 pCM007863_00025 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 pCM007863_00026 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCM007863_00026 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCM007863_00026 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCM007863_00026 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCM007863_00026 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pCM007863_00027 - 4.1e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCM007863_00027 - 7.7e-21 74.1 0.9 1.4e-20 73.3 0.9 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCM007863_00027 - 2.9e-07 29.8 0.9 6.6e-07 28.6 0.9 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCM007863_00027 - 0.013 15.6 3.4 1.5 8.8 0.0 3.7 4 1 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 pCM007863_00028 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCM007863_00028 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCM007863_00030 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Resolvase PF00239.21 pCM007863_00031 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCM007863_00031 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCM007863_00031 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_25 PF13481.6 pCM007863_00032 - 5.4e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCM007863_00032 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCM007863_00032 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCM007863_00032 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCM007863_00032 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCM007863_00032 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCM007863_00032 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 pCM007863_00033 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCM007863_00034 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCM007863_00036 - 0.0052 16.8 2.6 0.0069 16.4 2.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 pCM007863_00036 - 0.56 10.1 4.1 2 8.4 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 pCM007863_00037 - 0.027 14.4 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pCM007863_00037 - 0.045 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pCM007863_00037 - 0.068 13.6 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF4223 PF13978.6 pCM007863_00038 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) Toprim_3 PF13362.6 pCM007863_00039 - 2.1e-08 34.4 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pCM007863_00039 - 0.14 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCM007863_00039 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2004 PF09406.10 pCM007863_00040 - 0.12 12.7 3.0 0.62 10.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) Sds3 PF08598.11 pCM007863_00042 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCM007863_00042 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCM007863_00042 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCM007863_00043 - 0.00011 22.1 5.7 0.067 13.2 0.7 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCM007863_00043 - 0.058 13.5 1.9 0.087 12.9 1.4 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DndE PF08870.11 pCM007863_00043 - 0.31 11.3 5.7 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCM007863_00043 - 0.53 10.6 5.9 2.5 8.5 2.0 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pCM007863_00043 - 2 8.5 7.9 1 9.4 0.3 3.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Relaxase PF03432.14 pCM007863_00044 - 4.3e-09 36.3 8.2 4.3e-09 36.3 8.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF2768 PF10966.8 pCM007863_00045 - 0.053 14.0 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SNF2_N PF00176.23 pCM007863_00046 - 3e-16 59.1 1.8 5.1e-16 58.3 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCM007863_00046 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCM007863_00046 - 9.6e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCM007863_00046 - 8.1e-06 25.7 2.5 0.0012 18.7 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCM007863_00046 - 2.6e-05 24.7 0.7 0.00023 21.6 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCM007863_00047 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pCM007863_00047 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 pCM007863_00048 - 5.3e-05 23.2 0.6 0.001 19.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCM007863_00048 - 0.0012 18.9 0.5 0.0079 16.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Mur_ligase_C PF02875.21 pCM007863_00048 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCM007863_00048 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCM007863_00049 - 0.00028 21.0 1.6 0.00035 20.7 1.6 1.4 1 0 0 1 1 1 1 T-antigen specific domain CEBP_ZZ PF16366.5 pCM007863_00049 - 0.022 15.0 2.6 0.03 14.6 2.6 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1272 PF06906.11 pCM007863_00049 - 0.049 13.7 3.8 0.074 13.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Lip_prot_lig_C PF10437.9 pCM007865_00001 - 0.048 13.6 3.7 0.12 12.4 3.0 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus EptA_B_N PF08019.12 pCM007865_00003 - 0.12 12.3 10.8 0.053 13.4 1.6 2.3 1 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB FeoB_associated PF12669.7 pCM007865_00003 - 1.9 9.0 0.0 1.9 9.0 0.0 3.0 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DUF2070 PF09843.9 pCM007865_00003 - 7.9 4.6 18.3 9.6 4.4 18.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Topoisom_bac PF01131.20 pCM007865_00006 - 5.8e-97 325.3 7.7 8e-97 324.8 7.7 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCM007865_00006 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCM007865_00006 - 1.4e-08 34.4 14.8 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCM007865_00006 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCM007865_00006 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCM007865_00006 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pCM007865_00006 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCM007865_00006 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCM007865_00006 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCM007865_00006 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain FLYWCH PF04500.16 pCM007865_00006 - 0.14 12.3 3.1 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain HTH_34 PF13601.6 pCM007865_00006 - 0.47 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCM007865_00006 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCM007865_00006 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCM007865_00006 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCM007865_00006 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCM007865_00006 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pCM007865_00007 - 0.055 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCM007865_00008 - 0.039 13.8 0.5 0.039 13.8 0.5 1.8 2 0 0 2 2 2 0 PRELI-like family DUF2304 PF10066.9 pCM007865_00008 - 0.1 12.8 0.9 0.24 11.6 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Rsd_AlgQ PF04353.13 pCM007865_00008 - 1.3 8.9 6.1 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCM007865_00009 - 2.6e-35 121.7 1.4 3.6e-35 121.2 1.4 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCM007865_00010 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCM007865_00010 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCM007865_00010 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCM007865_00011 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCM007865_00011 - 9.9e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCM007865_00011 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCM007865_00011 - 0.046 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pCM007865_00012 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCM007865_00012 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCM007865_00012 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCM007865_00012 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCM007865_00012 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCM007865_00012 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCM007865_00012 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCM007865_00012 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCM007865_00012 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCM007865_00012 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCM007865_00012 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCM007865_00012 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCM007865_00012 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCM007865_00012 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCM007865_00012 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCM007865_00012 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCM007865_00012 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCM007865_00012 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCM007865_00012 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCM007865_00012 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCM007865_00012 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCM007865_00012 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCM007865_00012 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCM007865_00012 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCM007865_00012 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCM007865_00012 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCM007865_00012 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCM007865_00012 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCM007865_00012 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCM007865_00012 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCM007865_00012 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCM007865_00013 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCM007865_00013 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCM007865_00014 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCM007865_00014 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCM007865_00015 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCM007865_00015 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCM007865_00016 - 0.035 13.0 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCM007865_00016 - 1.5 8.6 5.2 2.6 7.9 5.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCM007865_00017 - 8.7e-31 107.4 31.2 8.7e-31 107.4 31.2 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T4SS PF07996.11 pCM007865_00018 - 2.2e-28 100.0 14.0 2.9e-28 99.6 14.0 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCM007865_00018 - 0.0037 17.4 0.4 0.015 15.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCM007865_00018 - 0.0089 16.7 5.2 0.0089 16.7 5.2 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCM007865_00018 - 0.064 12.8 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCM007865_00018 - 0.07 13.8 0.9 0.07 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain DHR10 PF18595.1 pCM007865_00018 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 pCM007865_00018 - 5.8 7.2 12.9 1.7 8.9 0.3 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 IF2_N PF04760.15 pCM007865_00019 - 6.5e-05 22.7 5.8 0.00049 19.9 2.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HTH_16 PF12645.7 pCM007865_00019 - 0.013 15.5 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCM007865_00019 - 0.029 15.1 0.5 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor FliG_N PF14842.6 pCM007865_00019 - 0.039 14.5 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain SSB PF00436.25 pCM007865_00020 - 1.4e-25 89.3 0.1 1.8e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 pCM007865_00021 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 pCM007865_00022 - 6.9e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCM007865_00022 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCM007865_00022 - 0.031 13.9 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCM007865_00022 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCM007865_00022 - 0.56 10.3 5.4 7.7 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pCM007865_00023 - 3.6e-49 167.7 0.3 9e-49 166.4 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCM007865_00023 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCM007865_00023 - 3.8e-07 29.4 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCM007865_00023 - 0.024 14.7 4.5 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 pCM007865_00024 - 1.2e-15 57.5 7.6 1.4e-15 57.3 7.6 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCM007865_00024 - 0.047 13.5 4.0 0.054 13.3 3.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCM007865_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCM007865_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pCM007865_00027 - 3.6e-33 114.7 0.7 4.5e-33 114.4 0.7 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCM007865_00027 - 0.027 14.2 1.2 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCM007865_00027 - 0.047 13.7 5.4 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCM007865_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pCM007865_00028 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCM007865_00028 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCM007865_00028 - 0.0021 17.8 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCM007865_00028 - 0.0072 15.7 0.0 0.058 12.7 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCM007865_00028 - 0.013 15.9 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCM007865_00028 - 0.2 11.7 2.0 0.95 9.5 2.0 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCM007865_00028 - 0.35 10.8 3.5 5.1 7.1 0.0 3.8 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) VASP_tetra PF08776.11 pCM007865_00028 - 3.8 7.2 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicA_toxin PF07927.12 pCM007865_00029 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCM007865_00030 - 4.2e-08 33.3 0.0 4.4e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCM007865_00032 - 0.0043 17.1 1.7 0.0054 16.8 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 pCM007865_00032 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 pCM007865_00033 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCM007865_00033 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pCM007865_00034 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCM007865_00034 - 0.017 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein Sds3 PF08598.11 pCM007865_00036 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCM007865_00036 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCM007865_00036 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCM007865_00037 - 0.00012 22.0 7.0 0.043 13.8 1.2 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCM007865_00037 - 0.063 13.4 2.6 0.071 13.2 1.5 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pCM007865_00037 - 0.47 10.8 6.1 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pCM007865_00037 - 0.53 10.4 9.0 1.5 8.9 0.4 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCM007865_00037 - 0.57 10.5 7.1 0.61 10.4 1.8 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pCM007865_00038 - 7.8e-10 38.8 7.7 7.8e-10 38.8 7.7 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain YqaJ PF09588.10 pCM007865_00038 - 0.03 14.5 3.9 0.24 11.6 0.4 3.0 2 1 1 3 3 3 0 YqaJ-like viral recombinase domain HTH_19 PF12844.7 pCM007865_00039 - 6.3e-06 26.1 0.3 0.024 14.6 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 pCM007865_00039 - 7.6e-06 25.9 0.0 6.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCM007865_00039 - 0.00035 20.6 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCM007865_00039 - 0.0024 17.4 0.1 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pCM007865_00039 - 0.0043 16.9 0.1 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_17 PF12728.7 pCM007865_00039 - 0.028 14.6 0.0 0.4 10.9 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 pCM007865_00039 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 pCM007865_00039 - 0.046 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_26 PF13443.6 pCM007865_00039 - 0.048 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Mga PF08280.11 pCM007865_00039 - 0.049 13.7 2.0 1.7 8.7 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 pCM007865_00039 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 pCM007865_00039 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pCM007865_00039 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Crp PF00325.20 pCM007865_00039 - 0.17 11.6 0.1 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family SNF2_N PF00176.23 pCM007865_00040 - 2.3e-16 59.4 3.1 2.9e-16 59.2 0.3 2.5 3 1 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCM007865_00040 - 3.2e-08 33.8 8.8 3.2e-08 33.8 8.8 4.1 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCM007865_00040 - 6.8e-07 29.6 1.6 2.4e-05 24.6 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCM007865_00040 - 9.8e-07 28.7 1.9 0.00054 19.8 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase BST2 PF16716.5 pCM007865_00040 - 4.3 8.0 7.3 8.1 7.1 2.7 3.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Eco57I PF07669.11 pCM007865_00041 - 1.2e-05 25.7 0.3 5e-05 23.8 0.3 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 pCM007865_00041 - 0.004 16.7 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 pCM007865_00042 - 8.5e-07 29.3 0.8 9.4e-07 29.1 0.8 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCM007865_00043 - 7.8e-05 22.7 0.5 0.0011 19.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCM007865_00043 - 0.00097 19.2 0.8 0.0077 16.3 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCM007865_00043 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pCM007865_00043 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCM007865_00044 - 0.02 15.0 7.2 0.03 14.5 7.2 1.4 1 1 0 1 1 1 0 T-antigen specific domain DUF1272 PF06906.11 pCM007865_00044 - 0.059 13.5 6.2 0.095 12.8 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CEBP_ZZ PF16366.5 pCM007865_00044 - 0.14 12.4 6.2 0.19 12.0 6.2 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain LIM PF00412.22 pCM007865_00044 - 0.23 11.7 8.9 0.4 10.9 8.9 1.4 1 0 0 1 1 1 0 LIM domain DUF5595 PF18077.1 pCM007865_00044 - 0.9 9.7 5.1 0.19 11.9 1.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) LysE PF01810.18 pCM007865_00045 - 5.1e-06 26.1 0.0 5.8e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCM007865_00045 - 0.00027 21.1 1.1 0.00031 20.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) Ac76 PF05814.11 pCM007865_00045 - 0.0043 17.0 2.2 0.0049 16.8 2.2 1.1 1 0 0 1 1 1 1 Orf76 (Ac76) Saf_2TM PF18303.1 pCM007865_00045 - 0.24 11.0 3.5 0.12 12.0 0.7 1.7 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF2873 PF11395.8 pCM007865_00045 - 3.7 7.5 6.8 0.78 9.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2873) LPAM_1 PF08139.12 pCM007865_00045 - 7.1 7.3 5.9 1.1 9.9 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Flp1_like PF16982.5 pCM007865_00046 - 0.044 13.2 3.1 0.044 13.2 3.1 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 pCM007865_00046 - 0.053 13.0 1.6 0.06 12.9 1.6 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 MAF_flag10 PF01973.18 pCM007884_00001 - 1.3e-43 148.6 1.0 2.7e-43 147.6 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF115 KASH_CCD PF14662.6 pCM007884_00001 - 0.0075 16.1 0.5 0.037 13.9 0.5 2.1 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 pCM007884_00001 - 0.072 13.3 4.3 0.33 11.2 2.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MAF_flag10 PF01973.18 pCM007884_00002 - 1.5e-42 145.2 1.3 2.9e-42 144.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF115 PspA_IM30 PF04012.12 pCM007884_00002 - 0.054 13.1 2.0 0.084 12.4 2.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family FliE PF02049.18 pCM007884_00002 - 0.086 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Sec2p PF06428.11 pCM007884_00002 - 0.26 11.3 7.2 0.83 9.7 7.2 1.9 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p eIF-4B PF06273.11 pCM007884_00002 - 1.3 8.0 4.0 1.9 7.5 4.0 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Mur_ligase_M PF08245.12 pCM007885_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 pCM007885_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 pCM007885_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 pCM007885_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 pCM007885_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 pCM007885_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 pCM007885_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 pCM007885_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 pCM007885_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 pCM007885_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 pCM007885_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 pCM007885_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 pCM007885_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 pCM007885_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 pCM007885_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 pCM007885_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 pCM007885_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 pCM007885_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 pCM007885_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 pCM007885_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 pCM007885_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 pCM007885_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 pCM007885_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 pCM007885_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 pCM007885_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 pCM007885_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 pCM007885_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 pCM007885_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 pCM007885_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 pCM007885_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 pCM007885_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 pCM007885_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 pCM007885_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 pCM007885_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 pCM007885_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 pCM007885_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 pCM007885_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 pCM007885_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 pCM007885_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 pCM007885_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 pCM007885_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 pCM007885_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 pCM007885_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 pCM007885_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 pCM007885_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 pCM007885_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 pCM007885_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 pCM007885_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 pCM007885_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 pCM007885_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 pCM007885_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 pCM007885_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 pCM007885_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 pCM007885_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 pCM007885_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 pCM007885_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 pCM007885_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 pCM007885_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 pCM007885_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 pCM007885_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 pCM007885_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 pCM007885_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 pCM007885_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 pCM007885_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 pCM007885_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 pCM007885_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 pCM007885_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 pCM007885_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 pCM007885_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 pCM007885_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 pCM007885_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 pCM007885_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 pCM007885_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 pCM007885_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 pCM007885_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 pCM007885_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 pCM007885_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 pCM007885_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 pCM007885_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 pCM007885_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 pCM007885_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain Mur_ligase_M PF08245.12 pCM007886_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 pCM007886_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 pCM007886_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 pCM007886_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 pCM007886_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 pCM007886_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 pCM007886_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 pCM007886_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 pCM007886_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 pCM007886_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 pCM007886_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 pCM007886_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 pCM007886_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 pCM007886_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 pCM007886_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 pCM007886_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 pCM007886_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 pCM007886_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 pCM007886_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 pCM007886_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 pCM007886_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 pCM007886_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 pCM007886_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 pCM007886_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 pCM007886_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 pCM007886_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 pCM007886_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 pCM007886_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 pCM007886_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 pCM007886_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 pCM007886_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 pCM007886_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 pCM007886_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 pCM007886_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 pCM007886_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 pCM007886_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 pCM007886_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 pCM007886_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 pCM007886_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 pCM007886_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 pCM007886_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 pCM007886_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 pCM007886_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 pCM007886_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 pCM007886_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 pCM007886_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 pCM007886_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 pCM007886_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 pCM007886_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 pCM007886_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 pCM007886_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 pCM007886_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 pCM007886_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 pCM007886_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 pCM007886_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 pCM007886_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 pCM007886_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 pCM007886_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 pCM007886_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 pCM007886_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 pCM007886_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 pCM007886_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 pCM007886_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 pCM007886_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 pCM007886_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 pCM007886_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 pCM007886_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 pCM007886_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 pCM007886_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 pCM007886_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 pCM007886_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 pCM007886_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 pCM007886_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 pCM007886_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 pCM007886_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 pCM007886_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 pCM007886_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 pCM007886_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 pCM007886_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 pCM007886_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 pCM007886_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain MAF_flag10 PF01973.18 pCM007887_00001 - 3.7e-42 143.9 0.7 5.4e-42 143.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF115 Med15_fungi PF05397.12 pCM007887_00001 - 0.011 16.0 0.7 0.15 12.4 0.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 Mur_ligase_M PF08245.12 pCM007888_00001 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 pCM007888_00001 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF4570 PF15134.6 pCM007888_00002 - 0.17 11.9 1.7 0.32 11.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) CTP_transf_3 PF02348.19 pCM007888_00003 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 pCM007888_00003 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 pCM007888_00003 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain PALP PF00291.25 pCM007888_00004 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 pCM007888_00004 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 pCM007888_00004 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain LpxK PF02606.14 pCM007888_00005 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 pCM007888_00005 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_synthase PF02540.17 pCM007888_00006 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 pCM007888_00006 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 pCM007888_00006 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 pCM007888_00006 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 pCM007888_00006 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 pCM007888_00006 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Lactamase_B PF00753.27 pCM007888_00007 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 pCM007888_00007 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1129 PF06570.11 pCM007888_00008 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) adh_short_C2 PF13561.6 pCM007888_00009 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 pCM007888_00009 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 pCM007888_00009 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 pCM007888_00009 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DHDPS PF00701.22 pCM007888_00010 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 pCM007888_00010 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Peptidase_M16_C PF05193.21 pCM007888_00011 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 pCM007888_00011 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 pCM007888_00011 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHO_dh PF01180.21 pCM007888_00012 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 pCM007888_00012 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 pCM007888_00012 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family ABC_membrane PF00664.23 pCM007888_00013 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 pCM007888_00013 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 pCM007888_00013 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 pCM007888_00013 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 pCM007888_00013 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 pCM007888_00013 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 pCM007888_00013 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 pCM007888_00013 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 pCM007888_00013 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 pCM007888_00013 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 pCM007888_00013 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_1e PF01406.19 pCM007888_00014 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 pCM007888_00014 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 pCM007888_00014 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 pCM007888_00014 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 pCM007888_00014 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 pCM007888_00014 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 pCM007888_00014 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) MurJ PF03023.14 pCM007888_00015 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 pCM007888_00015 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 FapA PF03961.13 pCM007888_00016 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 pCM007888_00016 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 pCM007888_00016 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 pCM007888_00016 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HHH_5 PF14520.6 pCM007888_00017 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 pCM007888_00017 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 pCM007888_00017 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 pCM007888_00017 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 pCM007888_00017 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 pCM007888_00017 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 pCM007888_00017 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 pCM007888_00017 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 pCM007888_00017 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 pCM007888_00017 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 pCM007888_00017 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 pCM007888_00017 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Dala_Dala_lig_C PF07478.13 pCM007888_00018 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 pCM007888_00018 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 pCM007888_00018 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 pCM007888_00018 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 pCM007888_00018 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 pCM007888_00018 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PhdYeFM_antitox PF02604.19 pCM007888_00019 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system W2 PF02020.18 pCP000549_00001 - 0.037 14.2 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pCP000549_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP000549_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP000549_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pCP000549_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP000549_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP000549_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP000549_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP000549_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP000549_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP000549_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pCP000549_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP000549_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP000549_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP000549_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP000549_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP000549_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP000549_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP000549_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP000549_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP000549_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP000549_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP000549_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP000549_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP000549_00009 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP000549_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP000549_00009 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP000549_00009 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP000549_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pCP000549_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP000549_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pCP000549_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP000549_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP000549_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP000549_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP000549_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP000549_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pCP000549_00013 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP000549_00013 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP000549_00013 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pCP000549_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP000549_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP000549_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP000549_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP000549_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP000549_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pCP000549_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pCP000549_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pCP000549_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pCP000549_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pCP000549_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pCP000549_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pCP000549_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP000549_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP000549_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP000549_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP000549_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP000549_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP000549_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP000549_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP000549_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP000549_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pCP000549_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP000549_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP000549_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP000549_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP000549_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP000549_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP000549_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP000549_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP000549_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP000549_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP000549_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP000549_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pCP000549_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP000549_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP000549_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP000549_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP000549_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP000549_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP000549_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP000549_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP000549_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pCP000549_00033 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP000549_00033 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP000549_00033 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP000549_00033 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 pCP000549_00033 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 pCP000549_00033 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pCP000549_00033 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pCP000549_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP000549_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP000549_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP000549_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP000549_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP000549_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP000549_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP000549_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP000549_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP000549_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP000549_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP000549_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP000549_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP000549_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP000549_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP000549_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP000549_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP000549_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP000549_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP000549_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP000549_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP000549_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP000549_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP000549_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP000549_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP000549_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP000549_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP000549_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP000549_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP000549_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP000549_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP000549_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP000549_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP000549_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP000549_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP000549_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP000549_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP000549_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP000549_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP000549_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP000549_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP000549_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP000549_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP000549_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP000549_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP000549_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP000549_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP000549_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP000549_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP000549_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP000549_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP000549_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP000549_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP000549_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP000549_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP000549_00046 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP000549_00046 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP000549_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP000549_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP000549_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP000549_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP000549_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP000549_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP000549_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP000549_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP000549_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP000549_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP000549_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP000549_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP000549_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP000549_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP000549_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP000549_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP000549_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP000549_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP000549_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP000549_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP000549_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP000549_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP000549_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP000549_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP000549_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP000549_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pCP000549_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pCP000549_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pCP004067_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP004067_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pCP004067_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP004067_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain DHHC PF01529.20 pCP004067_00004 - 4.1 7.5 13.1 13 5.9 13.1 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4133 PF13571.6 pCP004067_00004 - 5.6 7.4 7.4 7.5 7.0 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) DHHC PF01529.20 pCP004067_00006 - 0.033 14.3 6.3 0.039 14.0 6.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase T4SS_CagC PF16943.5 pCP004067_00006 - 0.046 13.9 0.2 0.056 13.6 0.2 1.1 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF4044 PF13253.6 pCP004067_00008 - 0.035 13.6 0.8 0.062 12.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP004067_00008 - 0.065 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2070 PF09843.9 pCP004067_00008 - 0.072 11.4 1.1 0.11 10.8 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP004067_00008 - 9.1 6.0 13.6 0.15 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP004067_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP004067_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) adh_short PF00106.25 pCP004067_00010 - 0.034 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP004067_00010 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 pCP004067_00011 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pCP004067_00011 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 pCP004067_00012 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP004067_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP004067_00012 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP004067_00012 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP004067_00012 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pCP004067_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pCP004067_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pCP004067_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pCP004067_00014 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP004067_00014 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pCP004067_00014 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 pCP004067_00014 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 pCP004067_00014 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 pCP004067_00014 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 pCP004067_00015 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 pCP004067_00016 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP004067_00017 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP004067_00017 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pCP004067_00017 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pCP004067_00017 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP004067_00017 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pCP004067_00018 - 1.1 9.1 11.3 0.26 11.1 5.3 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP004067_00018 - 1.4 9.3 6.9 0.31 11.3 1.2 2.1 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 pCP004067_00018 - 1.7 8.7 15.5 0.15 12.1 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function Ribonuc_2-5A PF06479.12 pCP004067_00022 - 0.065 13.4 5.2 0.2 11.9 5.2 1.9 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF5311 PF17238.2 pCP004067_00022 - 0.065 13.1 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Toprim_3 PF13362.6 pCP004067_00023 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP004067_00023 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP004067_00023 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP004067_00023 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP004067_00024 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pCP004067_00024 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 pCP004067_00025 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pCP004067_00025 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pCP004067_00025 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP004067_00027 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP004067_00028 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP004067_00029 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP004067_00029 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP004067_00029 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP004067_00029 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP004067_00029 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP004067_00029 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP004067_00029 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pCP004067_00030 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP004067_00030 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP004067_00030 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pCP004067_00031 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pCP004067_00033 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP004067_00033 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP004067_00034 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP004067_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pCP004067_00035 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pCP004067_00035 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pCP004067_00035 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 pCP004067_00036 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pCP004067_00037 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP004067_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP004067_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP004067_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP004067_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP004067_00039 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP004067_00039 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pCP004067_00039 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pCP004067_00039 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 pCP004067_00040 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP004067_00040 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pCP004067_00040 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 pCP004067_00040 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 pCP004067_00041 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 pCP004067_00042 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP004067_00042 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP004067_00043 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pCP004067_00044 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP004067_00044 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP004067_00045 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP004067_00045 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP004067_00045 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP004067_00045 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP004067_00045 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP004067_00045 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pCP004067_00045 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 pCP004067_00045 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP004067_00045 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP004067_00045 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP004067_00045 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP004067_00045 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pCP004067_00045 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pCP004067_00045 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pCP004067_00045 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pCP004067_00045 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pCP004067_00045 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pCP004067_00045 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pCP004067_00045 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pCP004067_00045 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pCP004067_00045 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pCP004067_00045 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP004067_00045 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP004067_00045 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP004067_00045 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP004067_00045 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP004067_00045 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP004067_00045 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pCP004067_00045 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 pCP004067_00045 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP004067_00045 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP004067_00045 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 pCP004067_00046 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 pCP004067_00047 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP004067_00047 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP004067_00047 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pCP004067_00047 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 pCP004067_00047 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 pCP004067_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP004067_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pCP004067_00049 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP004067_00050 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pCP004067_00050 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 pCP004067_00051 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pCP004067_00051 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pCP004067_00051 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pCP004067_00052 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pCP004067_00053 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP004067_00053 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP004067_00053 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP004067_00053 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP004067_00053 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP004067_00053 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP004067_00053 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP004067_00053 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP004067_00053 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP004067_00053 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP004067_00053 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP004067_00053 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP004067_00053 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP004067_00053 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP004067_00053 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP004067_00053 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP004067_00053 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP004067_00054 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP004067_00054 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain APH PF01636.23 pCP004067_00056 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 pCP004067_00056 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 pCP004067_00056 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 pCP004067_00056 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 pCP004067_00056 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 pCP004067_00057 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP004067_00057 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP004067_00057 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP004067_00057 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP004067_00057 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP004067_00057 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP004067_00057 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP004067_00057 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP004067_00057 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 pCP004067_00059 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 pCP004067_00059 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 pCP004067_00059 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 pCP004067_00059 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 pCP004067_00059 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 pCP004067_00060 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 pCP004067_00061 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pCP004067_00061 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pCP004067_00061 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pCP004067_00061 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 pCP004067_00062 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 pCP004067_00063 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP004067_00063 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pCP004067_00063 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pCP004067_00063 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pCP004067_00063 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pCP004067_00063 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pCP004067_00063 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pCP004067_00063 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pCP004067_00063 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pCP004067_00063 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pCP004067_00063 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pCP004067_00063 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 pCP004067_00063 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 pCP004067_00063 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 pCP004067_00063 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 pCP004067_00063 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 pCP004067_00063 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP004067_00063 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pCP004067_00063 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 pCP004067_00063 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 pCP004067_00063 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 pCP004067_00063 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 pCP004067_00063 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 pCP004067_00063 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 pCP004067_00063 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 pCP004067_00063 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 pCP004067_00063 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 pCP004067_00063 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 pCP004067_00063 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 pCP004067_00063 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 pCP004067_00063 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 pCP004067_00063 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 pCP004067_00063 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pCP004067_00063 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 pCP004067_00063 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 pCP004067_00063 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 pCP004067_00063 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 pCP004067_00064 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP004067_00064 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP004067_00064 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP004067_00064 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP004067_00064 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP004067_00064 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP004067_00065 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pCP004067_00066 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pCP004067_00067 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pCP004067_00067 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pCP004067_00067 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pCP004067_00067 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pCP004067_00067 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pCP004067_00067 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pCP004067_00067 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pCP004067_00067 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pCP004067_00068 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP004067_00068 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP004067_00068 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 pCP004067_00069 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 pCP004067_00069 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 pCP004067_00069 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 pCP004067_00070 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 pCP004067_00070 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 pCP004067_00070 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain W2 PF02020.18 pCP007180_00001 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pCP007180_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP007180_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP007180_00003 - 0.0072 15.7 2.9 0.0072 15.7 2.9 1.6 2 0 0 2 2 2 1 Putative Flagellin, Flp1-like, domain Y1_Tnp PF01797.16 pCP007180_00004 - 4e-36 123.8 1.9 4.7e-36 123.6 1.9 1.1 1 0 0 1 1 1 1 Transposase IS200 like Symplekin_C PF12295.8 pCP007180_00004 - 0.042 14.0 0.2 0.049 13.7 0.2 1.1 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal DUF4974 PF16344.5 pCP007180_00004 - 0.47 10.5 3.6 0.16 12.0 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) OrfB_Zn_ribbon PF07282.11 pCP007180_00005 - 3.2e-21 75.0 0.5 6.9e-21 73.9 0.5 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 pCP007180_00005 - 2.4e-20 71.7 1.5 4.8e-20 70.8 1.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 pCP007180_00005 - 7.6e-20 71.3 2.2 1.9e-19 70.0 2.2 1.6 1 0 0 1 1 1 1 Probable transposase HypA PF01155.19 pCP007180_00005 - 0.19 11.7 0.7 0.42 10.6 0.7 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 pCP007180_00005 - 0.32 11.1 1.5 1.3 9.2 1.5 2.1 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 pCP007180_00005 - 2.3 7.7 5.7 16 5.0 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 pCP007180_00005 - 3.9 7.5 5.0 3.2 7.8 2.0 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ima1_N PF09779.9 pCP007180_00005 - 5 8.0 7.5 1.7 9.5 0.7 2.9 2 1 1 3 3 3 0 Ima1 N-terminal domain LysE PF01810.18 pCP007180_00006 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP007180_00006 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP007180_00006 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP007180_00006 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP007180_00006 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP007180_00006 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP007180_00006 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP007180_00006 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP007180_00006 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP007180_00007 - 0.0042 16.6 1.2 0.0059 16.1 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4044) NPA PF16469.5 pCP007180_00008 - 0.057 14.0 6.1 0.06 13.9 6.1 1.0 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Papo_T_antigen PF02380.15 pCP007180_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP007180_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP007180_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP007180_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP007180_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP007180_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP007180_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP007180_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP007180_00012 - 1.7e-16 59.9 1.2 4e-16 58.7 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP007180_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP007180_00012 - 9.6e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP007180_00012 - 6.3e-06 26.1 1.8 0.0012 18.7 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP007180_00012 - 1.5e-05 25.5 0.7 0.00015 22.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pCP007180_00013 - 1.1e-09 38.9 1.0 4.7e-09 36.9 1.0 2.0 1 1 0 1 1 1 1 NYN domain HTH_19 PF12844.7 pCP007180_00014 - 7.3e-06 25.9 0.1 0.012 15.6 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pCP007180_00014 - 7.9e-06 25.8 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCP007180_00014 - 0.00077 19.5 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCP007180_00014 - 0.0073 15.8 0.0 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pCP007180_00014 - 0.0088 16.1 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP007180_00014 - 0.01 15.7 0.2 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pCP007180_00014 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 pCP007180_00014 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 pCP007180_00014 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 pCP007180_00014 - 0.073 12.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Relaxase PF03432.14 pCP007180_00015 - 4.1e-10 39.7 7.6 4.1e-10 39.7 7.6 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP007180_00016 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP007180_00016 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP007180_00016 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP007180_00016 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP007180_00016 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Sds3 PF08598.11 pCP007180_00017 - 0.027 14.5 5.8 0.032 14.3 5.8 1.1 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP007180_00017 - 0.21 11.4 8.2 0.23 11.3 5.3 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3671 PF12420.8 pCP007180_00017 - 4.6 7.3 14.1 0.42 10.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function CdiI PF07262.11 pCP007180_00017 - 8.8 6.1 12.2 16 5.3 12.2 1.5 1 1 0 1 1 1 0 CDI immunity protein DUF2400 PF09674.10 pCP007180_00019 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP007180_00020 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP007180_00020 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP007180_00020 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP007180_00020 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP007180_00021 - 0.0028 17.6 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pCP007180_00022 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pCP007180_00022 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pCP007180_00022 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP007180_00024 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP007180_00025 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP007180_00026 - 5.4e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP007180_00026 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP007180_00026 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP007180_00026 - 0.0088 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP007180_00026 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP007180_00026 - 0.21 11.7 2.2 1.1 9.4 2.2 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP007180_00026 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pCP007180_00027 - 1.3e-33 116.2 0.8 2.2e-33 115.4 0.8 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain CRISPR_Cas2 PF09827.9 pCP007180_00027 - 0.0016 18.5 0.0 0.016 15.3 0.0 2.6 1 1 0 1 1 1 1 CRISPR associated protein Cas2 PAS_11 PF14598.6 pCP007180_00027 - 0.0032 17.6 1.2 0.023 14.8 0.4 2.3 2 0 0 2 2 2 1 PAS domain Occludin_ELL PF07303.13 pCP007180_00027 - 0.12 13.1 9.1 0.043 14.5 6.0 1.8 2 0 0 2 2 2 0 Occludin homology domain HTH_38 PF13936.6 pCP007180_00027 - 0.2 11.5 1.5 22 4.9 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Pox_A_type_inc PF04508.12 pCP007180_00027 - 6.5 6.8 6.9 0.97 9.4 2.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TrbC PF04956.13 pCP007180_00029 - 1.5e-14 54.0 8.5 1.6e-14 53.9 8.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP007180_00029 - 0.056 13.3 4.3 0.073 12.9 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) VirB3 PF05101.13 pCP007180_00030 - 2e-13 50.4 1.9 2.1e-13 50.3 1.9 1.0 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein CagE_TrbE_VirB PF03135.14 pCP007180_00031 - 3.7e-51 174.2 0.6 8.4e-51 173.0 0.6 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system HNOBA PF07701.14 pCP007180_00031 - 0.039 13.4 0.1 0.085 12.3 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP007180_00032 - 3.1e-31 107.8 0.1 5e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) FapA PF03961.13 pCP007180_00033 - 0.0039 15.9 6.9 0.0039 15.9 6.9 1.6 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 pCP007180_00033 - 0.028 14.3 4.0 0.028 14.3 4.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Fib_alpha PF08702.10 pCP007180_00033 - 0.6 10.3 12.2 0.061 13.5 4.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 pCP007180_00033 - 1.7 8.4 11.6 0.92 9.3 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator Striatin PF08232.12 pCP007180_00033 - 4.6 7.8 9.6 14 6.2 9.6 1.9 1 1 0 1 1 1 0 Striatin family Syntaxin-6_N PF09177.11 pCP007180_00033 - 9.3 6.9 10.2 1.8 9.2 4.5 2.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal SSB PF00436.25 pCP007180_00035 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP007180_00036 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP007180_00036 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP007180_00036 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP007180_00036 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP007180_00037 - 3.9e-12 47.0 0.4 4.8e-12 46.7 0.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins GldM_N PF12081.8 pCP007180_00037 - 0.033 14.3 0.5 0.054 13.6 0.5 1.4 1 0 0 1 1 1 0 GldM N-terminal domain T4SS PF07996.11 pCP007180_00038 - 3.3e-10 40.7 11.1 3.8e-10 40.5 11.1 1.0 1 0 0 1 1 1 1 Type IV secretion system proteins AATF-Che1 PF13339.6 pCP007180_00038 - 0.0044 17.7 2.4 0.0052 17.5 2.4 1.1 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DHR10 PF18595.1 pCP007180_00038 - 0.023 14.7 5.2 0.031 14.3 5.2 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 pCP007180_00038 - 0.032 14.9 0.6 0.032 14.9 0.6 2.0 1 1 0 2 2 2 0 Occludin homology domain VWA_2 PF13519.6 pCP007180_00038 - 0.067 13.8 1.1 0.1 13.3 0.8 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain Snapin_Pallidin PF14712.6 pCP007180_00038 - 0.1 13.0 5.1 0.28 11.6 5.1 1.8 1 1 0 1 1 1 0 Snapin/Pallidin TrbL PF04610.14 pCP007180_00039 - 8.7e-32 110.6 33.1 8.7e-32 110.6 33.1 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP007180_00039 - 0.029 14.2 1.4 0.055 13.3 0.1 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 pCP007180_00040 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pCP007180_00040 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pCP007180_00040 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP007180_00041 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP007180_00041 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP007180_00042 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pCP007180_00042 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 pCP007180_00042 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pCP007180_00043 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP007180_00043 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP007180_00044 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP007180_00044 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP007180_00044 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP007180_00044 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP007180_00044 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP007180_00044 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pCP007180_00044 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pCP007180_00044 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP007180_00044 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP007180_00044 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP007180_00044 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP007180_00044 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pCP007180_00044 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pCP007180_00044 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pCP007180_00044 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pCP007180_00044 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pCP007180_00044 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pCP007180_00044 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pCP007180_00044 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pCP007180_00044 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP007180_00044 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 pCP007180_00044 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 pCP007180_00044 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP007180_00044 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP007180_00044 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP007180_00044 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP007180_00044 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP007180_00044 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pCP007180_00044 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 pCP007180_00044 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP007180_00044 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP007180_00044 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP007180_00045 - 1e-105 354.3 0.1 1.4e-105 353.8 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP007180_00045 - 1.1e-24 86.8 0.0 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP007180_00045 - 6.5e-16 58.2 0.0 1.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pCP007180_00045 - 0.2 11.7 0.2 0.34 10.9 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 pCP007180_00046 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP007180_00046 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pCP007180_00047 - 1.1e-36 126.1 1.8 1.3e-36 125.8 1.8 1.0 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP007180_00048 - 0.03 14.1 2.2 0.033 14.0 0.3 2.0 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pCP007180_00048 - 2.4 7.9 10.1 5 6.9 8.4 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NdhM PF10664.9 pCP007180_00048 - 2.5 8.4 6.1 57 4.0 0.3 3.2 2 1 1 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M IFT20 PF14931.6 pCP007180_00048 - 4.8 7.4 10.0 1.3 9.2 0.8 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Mod_r PF07200.13 pCP007180_00048 - 8.2 6.5 12.0 85 3.2 9.1 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CdhD PF03599.16 pCP007180_00049 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pCP007180_00049 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pCP007180_00049 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pCP007180_00050 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pCP007180_00051 - 9e-97 324.7 8.0 1.3e-96 324.2 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP007180_00051 - 9.7e-12 45.0 0.1 9.7e-12 45.0 0.1 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP007180_00051 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP007180_00051 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP007180_00051 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP007180_00051 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP007180_00051 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 pCP007180_00051 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 pCP007180_00051 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP007180_00051 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pCP007180_00051 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP007180_00051 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP007180_00051 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP007180_00051 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP007180_00051 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP007180_00051 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP007180_00051 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP007180_00053 - 3.9e-05 23.6 2.2 0.0001 22.2 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP007180_00053 - 0.02 14.9 4.4 0.16 11.9 4.4 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP007180_00055 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP007180_00055 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP007180_00055 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP007180_00055 - 3e-12 46.4 0.1 6.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP007180_00055 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP007180_00055 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP007180_00055 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP007180_00055 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP007180_00055 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family W2 PF02020.18 pCP007182_00001 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pCP007182_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP007182_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 pCP007182_00003 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP007182_00003 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP007182_00003 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP007182_00003 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP007182_00003 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP007182_00003 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP007182_00003 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP007182_00003 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP007182_00003 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP007182_00004 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP007182_00004 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP007182_00004 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP007182_00004 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP007182_00004 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP007182_00005 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP007182_00005 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP007182_00006 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP007182_00006 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP007182_00006 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP007182_00006 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP007182_00006 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase SNF2_N PF00176.23 pCP007182_00008 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP007182_00008 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP007182_00008 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP007182_00008 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP007182_00008 - 2.9e-05 24.5 0.6 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pCP007182_00009 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP007182_00009 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pCP007182_00010 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP007182_00011 - 5.2e-05 23.2 6.1 0.063 13.3 1.0 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP007182_00011 - 0.036 14.2 2.3 0.046 13.8 1.6 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP007182_00011 - 0.21 11.7 7.8 0.93 9.6 0.3 2.9 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Imm41 PF15592.6 pCP007182_00012 - 0.031 14.6 2.2 0.034 14.5 2.2 1.0 1 0 0 1 1 1 0 Immunity protein 41 DUF2400 PF09674.10 pCP007182_00014 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP007182_00015 - 1.9e-08 34.5 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP007182_00015 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP007182_00015 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP007182_00015 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP007182_00016 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pCP007182_00017 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pCP007182_00017 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pCP007182_00017 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP007182_00019 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP007182_00020 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP007182_00021 - 1.6e-14 54.0 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP007182_00021 - 0.00038 19.9 0.0 0.0019 17.6 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP007182_00021 - 0.0022 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP007182_00021 - 0.009 16.4 0.2 0.22 11.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP007182_00021 - 0.0091 15.4 0.0 0.058 12.7 0.0 2.3 2 1 0 2 2 2 1 KaiC CbiA PF01656.23 pCP007182_00021 - 0.16 12.0 1.6 0.74 9.9 1.6 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP007182_00021 - 0.37 10.8 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pCP007182_00022 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP007182_00022 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP007182_00022 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP007182_00022 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP007182_00023 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP007182_00023 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP007182_00025 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP007182_00025 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP007182_00026 - 3.3e-50 171.1 0.4 7.5e-50 169.9 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP007182_00026 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP007182_00026 - 0.046 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP007182_00027 - 3e-29 101.4 0.0 4.8e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP007182_00027 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 pCP007182_00027 - 0.071 13.1 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) DUF3251 PF11622.8 pCP007182_00028 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP007182_00028 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP007182_00028 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP007182_00028 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP007182_00028 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP007182_00028 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP007182_00029 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP007182_00030 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP007182_00030 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP007182_00030 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP007182_00030 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP007182_00031 - 5.3e-28 98.8 13.9 6.9e-28 98.4 13.9 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP007182_00031 - 0.0037 17.4 0.4 0.016 15.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP007182_00031 - 0.0077 16.9 5.4 0.0077 16.9 5.4 2.4 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP007182_00031 - 0.064 12.8 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP007182_00031 - 0.11 13.2 3.6 0.08 13.6 1.1 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCP007182_00031 - 3.8 7.8 11.9 1.6 9.0 0.2 2.9 2 1 1 3 3 3 0 Tho complex subunit 7 DHR10 PF18595.1 pCP007182_00031 - 5.9 7.0 14.5 0.64 10.1 6.3 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pCP007182_00032 - 2.9e-31 108.9 34.2 2.9e-31 108.9 34.2 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP007182_00032 - 0.059 13.2 2.2 0.093 12.5 0.2 2.4 2 1 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP007182_00032 - 0.29 12.1 6.0 0.57 11.1 6.0 1.5 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 VirB8 PF04335.13 pCP007182_00034 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP007182_00034 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP007182_00035 - 2e-54 184.5 1.3 3.3e-54 183.8 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP007182_00035 - 0.053 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP007182_00036 - 5.5e-48 163.3 0.1 5.5e-48 163.3 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP007182_00036 - 0.027 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP007182_00037 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP007182_00037 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP007182_00037 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP007182_00037 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP007182_00037 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP007182_00037 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP007182_00037 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP007182_00037 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP007182_00037 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP007182_00037 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP007182_00037 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP007182_00037 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP007182_00037 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP007182_00037 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP007182_00037 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP007182_00037 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP007182_00037 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP007182_00037 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP007182_00037 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP007182_00037 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP007182_00037 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP007182_00037 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP007182_00037 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP007182_00037 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP007182_00037 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP007182_00037 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP007182_00037 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP007182_00037 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP007182_00037 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP007182_00037 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP007182_00037 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP007182_00038 - 7.4e-106 354.7 0.1 1e-105 354.3 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP007182_00038 - 9.5e-25 87.0 0.0 1.9e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP007182_00038 - 3.7e-15 55.7 0.0 1.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 pCP007182_00039 - 1.5e-16 60.7 0.2 2e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP007182_00039 - 0.061 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pCP007182_00040 - 2.1e-38 131.7 1.2 2.8e-38 131.3 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP007182_00041 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP007182_00041 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP007182_00041 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP007182_00043 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP007182_00044 - 1.4e-96 324.0 8.0 2e-96 323.6 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP007182_00044 - 1e-11 44.9 0.0 1e-11 44.9 0.0 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP007182_00044 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP007182_00044 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP007182_00044 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP007182_00044 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP007182_00044 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 pCP007182_00044 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 pCP007182_00044 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP007182_00044 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pCP007182_00044 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP007182_00044 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP007182_00044 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP007182_00044 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP007182_00044 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP007182_00044 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP007182_00044 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NmrA PF05368.13 pCP007182_00046 - 0.017 14.7 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family GTP_EFTU PF00009.27 pCP007182_00048 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP007182_00048 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP007182_00048 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP007182_00048 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP007182_00048 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP007182_00048 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP007182_00048 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP007182_00048 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP007182_00048 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 pCP007182_00049 - 1.5e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP007182_00049 - 3.5e-06 27.0 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pCP007182_00049 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pCP007182_00049 - 0.088 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication APH PF01636.23 pCP007182_00050 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP007182_00050 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP007182_00050 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP007182_00050 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP007182_00050 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP007182_00050 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP007182_00051 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pCP007182_00052 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pCP007182_00053 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pCP007182_00053 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pCP007182_00053 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pCP007182_00053 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pCP007182_00053 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pCP007182_00053 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pCP007182_00053 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pCP007182_00053 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pCP007182_00054 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP007182_00054 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP007182_00054 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family TrbC PF04956.13 pCP007750_00002 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP007750_00002 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP007750_00004 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP007750_00004 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pCP007750_00005 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP007750_00005 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP007750_00005 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP007750_00005 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pCP007750_00006 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP007750_00006 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP007750_00006 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP007750_00006 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP007750_00006 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP007750_00006 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP007750_00006 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 pCP007750_00007 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCP007750_00008 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pCP007750_00008 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pCP007750_00008 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 pCP007750_00009 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pCP007750_00009 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pCP007750_00009 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pCP007750_00009 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 pCP007750_00010 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP007750_00010 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pCP007750_00011 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP007750_00011 - 0.074 13.0 0.3 0.33 10.9 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP007750_00011 - 0.13 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP007750_00011 - 0.27 11.9 5.3 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pCP007750_00012 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) CdvA PF18822.1 pCP007750_00014 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pCP007750_00014 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pCP007750_00014 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCP007750_00015 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP007750_00015 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP007750_00015 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP007750_00015 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP007750_00015 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pCP007750_00016 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 pCP007750_00017 - 9.3e-06 25.6 0.1 0.016 15.3 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pCP007750_00017 - 9.6e-06 25.6 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCP007750_00017 - 0.00071 19.6 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCP007750_00017 - 0.0073 15.8 0.0 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pCP007750_00017 - 0.0089 16.1 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP007750_00017 - 0.011 15.6 0.2 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pCP007750_00017 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 pCP007750_00017 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 pCP007750_00017 - 0.065 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 pCP007750_00017 - 0.073 12.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain NYN PF01936.18 pCP007750_00018 - 1.1e-09 38.9 1.0 4.7e-09 36.9 1.0 2.0 1 1 0 1 1 1 1 NYN domain SNF2_N PF00176.23 pCP007750_00019 - 1.7e-16 59.9 1.1 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP007750_00019 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP007750_00019 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP007750_00019 - 6.2e-06 26.1 1.6 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP007750_00019 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP007750_00020 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCP007750_00021 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP007750_00021 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP007750_00021 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP007750_00021 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP007750_00021 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP007750_00022 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP007750_00022 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP007750_00023 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP007750_00023 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP007750_00023 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP007750_00023 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP007750_00023 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP007750_00024 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP007750_00024 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP007750_00024 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP007750_00024 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP007750_00024 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP007750_00024 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP007750_00024 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pCP007750_00025 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 pCP007750_00026 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP007750_00026 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pCP007750_00027 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP007750_00027 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain DUF5442 PF17514.2 pCP007750_00029 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) GTP_EFTU PF00009.27 pCP007750_00030 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP007750_00030 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP007750_00030 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP007750_00030 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP007750_00030 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP007750_00030 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP007750_00030 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP007750_00030 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP007750_00030 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pCP007750_00032 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP007750_00032 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pCP007750_00033 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP007750_00033 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP007750_00033 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP007750_00033 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP007750_00033 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP007750_00033 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP007750_00033 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP007750_00033 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP007750_00033 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP007750_00033 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP007750_00033 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP007750_00033 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP007750_00033 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP007750_00033 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP007750_00033 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP007750_00033 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP007750_00033 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pCP007750_00034 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP007750_00036 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP007750_00036 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP007750_00036 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCP007750_00037 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP007750_00038 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP007750_00038 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP007750_00038 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP007750_00038 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCP007750_00039 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP007750_00039 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP007750_00039 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP007750_00039 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pCP007750_00040 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP007750_00040 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP007750_00040 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP007750_00040 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP007750_00040 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP007750_00040 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP007750_00040 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP007750_00040 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP007750_00040 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP007750_00040 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP007750_00040 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP007750_00040 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP007750_00040 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP007750_00040 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP007750_00040 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP007750_00040 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP007750_00040 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP007750_00040 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP007750_00040 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP007750_00040 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP007750_00040 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP007750_00040 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP007750_00040 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP007750_00040 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP007750_00040 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP007750_00040 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP007750_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP007750_00040 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP007750_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP007750_00040 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP007750_00040 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP007750_00041 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP007750_00041 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP007750_00042 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP007750_00042 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCP007750_00043 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP007750_00043 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP007750_00044 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP007750_00044 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP007750_00045 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP007750_00045 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP007750_00045 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pCP007750_00046 - 1.6e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP007750_00046 - 0.0055 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP007750_00046 - 0.015 16.0 5.3 0.015 16.0 5.3 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP007750_00046 - 0.018 15.7 1.0 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCP007750_00046 - 2.9 8.2 11.5 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pCP007750_00046 - 5.1 7.2 14.8 0.55 10.3 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pCP007750_00047 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP007750_00047 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP007750_00047 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP007750_00047 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP007750_00048 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 pCP007750_00049 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP007750_00049 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP007750_00049 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP007750_00049 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP007750_00049 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP007750_00049 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 pCP007750_00050 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP007750_00050 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP007750_00050 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP007750_00050 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP007750_00050 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pCP007750_00051 - 1.6e-28 100.2 0.0 4.5e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system HNOBA PF07701.14 pCP007750_00051 - 0.022 14.2 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 pCP007750_00051 - 0.2 11.6 0.0 0.54 10.2 0.0 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like TrbC PF04956.13 pCP007752_00003 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP007752_00003 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP007752_00005 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP007752_00005 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pCP007752_00006 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP007752_00006 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP007752_00006 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP007752_00006 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pCP007752_00007 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP007752_00007 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP007752_00007 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP007752_00007 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP007752_00007 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP007752_00007 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP007752_00007 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 pCP007752_00008 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system UBA_6 PF18039.1 pCP007752_00011 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pCP007752_00011 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pCP007752_00011 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pCP007752_00011 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 pCP007752_00012 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP007752_00012 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pCP007752_00013 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP007752_00013 - 0.074 13.0 0.3 0.33 10.9 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP007752_00013 - 0.13 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP007752_00013 - 0.27 11.9 5.3 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pCP007752_00014 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) CdvA PF18822.1 pCP007752_00016 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pCP007752_00016 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pCP007752_00016 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCP007752_00017 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP007752_00017 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP007752_00017 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP007752_00017 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP007752_00017 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pCP007752_00018 - 2.1e-10 40.6 7.3 2.1e-10 40.6 7.3 2.6 1 1 1 2 2 2 1 Relaxase/Mobilisation nuclease domain Acetyltransf_7 PF13508.7 pCP007752_00019 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP007752_00019 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family SNF2_N PF00176.23 pCP007752_00020 - 2.3e-16 59.4 3.3 2.7e-16 59.3 0.4 2.5 3 1 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP007752_00020 - 3.3e-08 33.7 8.7 3.3e-08 33.7 8.7 4.1 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP007752_00020 - 9.9e-07 29.1 1.8 2.7e-05 24.5 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP007752_00020 - 1.4e-06 28.2 1.4 0.00061 19.6 0.3 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase BST2 PF16716.5 pCP007752_00020 - 2.6 8.7 5.8 11 6.7 2.0 3.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Eco57I PF07669.11 pCP007752_00021 - 5.7e-06 26.8 0.9 8e-05 23.1 0.2 2.8 2 0 0 2 2 2 1 Eco57I restriction-modification methylase MTS PF05175.14 pCP007752_00021 - 0.0039 16.8 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 pCP007752_00022 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCP007752_00023 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP007752_00023 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP007752_00023 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP007752_00023 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP007752_00023 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP007752_00024 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP007752_00024 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) NPA PF16469.5 pCP007752_00025 - 0.02 15.5 5.1 0.025 15.1 5.1 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF4044 PF13253.6 pCP007752_00026 - 0.012 15.1 1.1 0.019 14.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) DUF443 PF04276.12 pCP007752_00026 - 0.013 15.3 6.9 0.014 15.2 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Claudin_2 PF13903.6 pCP007752_00026 - 0.03 14.1 1.0 0.034 13.9 1.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Popeye PF04831.13 pCP007752_00026 - 0.16 12.1 2.0 0.16 12.1 1.2 1.4 1 1 0 1 1 1 0 Popeye protein conserved region LysE PF01810.18 pCP007752_00027 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP007752_00027 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP007752_00027 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP007752_00027 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP007752_00027 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP007752_00027 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP007752_00027 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pCP007752_00028 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 pCP007752_00029 - 0.036 14.2 0.3 3.4 7.9 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pCP007752_00030 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon APH PF01636.23 pCP007752_00031 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP007752_00031 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP007752_00031 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Peptidase_C15 PF01470.17 pCP007752_00032 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pCP007752_00033 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP007752_00033 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP007752_00033 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP007752_00033 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP007752_00033 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP007752_00033 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_18 PF13238.6 pCP007752_00034 - 1.5e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP007752_00034 - 3.5e-06 27.0 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pCP007752_00034 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pCP007752_00034 - 0.088 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication GTP_EFTU PF00009.27 pCP007752_00035 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP007752_00035 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP007752_00035 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP007752_00035 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP007752_00035 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP007752_00035 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP007752_00035 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP007752_00035 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP007752_00035 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pCP007752_00037 - 0.00071 19.5 1.8 0.0021 18.0 1.8 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP007752_00037 - 0.033 14.1 2.9 0.25 11.3 2.9 2.4 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pCP007752_00039 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP007752_00039 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP007752_00039 - 1.4e-08 34.4 15.0 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP007752_00039 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP007752_00039 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP007752_00039 - 0.028 14.8 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pCP007752_00039 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP007752_00039 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP007752_00039 - 0.088 12.7 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP007752_00039 - 0.089 13.1 4.5 0.89 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP007752_00039 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP007752_00039 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP007752_00039 - 0.64 10.0 3.8 4.6 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP007752_00039 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP007752_00039 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP007752_00039 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pCP007752_00040 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP007752_00042 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP007752_00042 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP007752_00042 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCP007752_00043 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP007752_00044 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP007752_00044 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP007752_00044 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP007752_00044 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCP007752_00045 - 6.6e-104 348.3 0.0 1e-103 347.7 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP007752_00045 - 6.6e-25 87.5 0.0 1.5e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP007752_00045 - 9.9e-15 54.3 0.0 8.6e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP007752_00045 - 0.037 14.2 0.1 0.084 13.0 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pCP007752_00047 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP007752_00047 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP007752_00047 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP007752_00047 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP007752_00047 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP007752_00047 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP007752_00047 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP007752_00047 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP007752_00047 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP007752_00047 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP007752_00047 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP007752_00047 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP007752_00047 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP007752_00047 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP007752_00047 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP007752_00047 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP007752_00047 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP007752_00047 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP007752_00047 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP007752_00047 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP007752_00047 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP007752_00047 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP007752_00047 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP007752_00047 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP007752_00047 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP007752_00047 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP007752_00047 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP007752_00047 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP007752_00047 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP007752_00047 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP007752_00047 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP007752_00048 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP007752_00048 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP007752_00049 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP007752_00049 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCP007752_00050 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP007752_00050 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP007752_00051 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP007752_00051 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP007752_00052 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP007752_00052 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP007752_00052 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pCP007752_00053 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP007752_00053 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP007752_00053 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP007752_00053 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP007752_00053 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCP007752_00053 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pCP007752_00053 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pCP007752_00053 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pCP007752_00054 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP007752_00054 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP007752_00054 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP007752_00054 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP007752_00055 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 pCP007752_00056 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP007752_00056 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP007752_00056 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP007752_00056 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP007752_00056 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP007752_00056 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 pCP007752_00057 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP007752_00057 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP007752_00057 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP007752_00057 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP007752_00057 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 bZIP_1 PF00170.21 pCP007752_00058 - 0.68 10.1 5.2 5 7.3 0.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor TraC_F_IV PF11130.8 pCP009044_00001 - 7.6e-30 104.3 0.0 1.4e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 pCP009044_00001 - 3.3e-10 39.4 0.0 1.7e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 pCP009044_00001 - 0.00074 18.5 0.0 0.8 8.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 pCP009044_00001 - 0.0072 16.6 0.1 4.1 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zot PF05707.12 pCP009044_00001 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) FH2 PF02181.23 pCP009044_00001 - 0.016 14.4 1.1 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain CbiA PF01656.23 pCP009044_00001 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0181 PF03701.14 pCP009044_00001 - 0.22 11.2 0.5 0.67 9.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) TrbI_Ftype PF09677.10 pCP009044_00002 - 2.1e-05 24.8 1.3 2.5e-05 24.6 1.3 1.4 1 1 0 1 1 1 1 Type-F conjugative transfer system protein (TrbI_Ftype) Peptidase_S26 PF10502.9 pCP009044_00003 - 2.2e-13 50.2 0.0 3.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 TraH PF06122.11 pCP009044_00004 - 5.6e-68 229.8 2.0 7.8e-68 229.4 2.0 1.2 1 0 0 1 1 1 1 Conjugative relaxosome accessory transposon protein TraN PF06986.11 pCP009044_00006 - 4.3e-29 101.9 9.8 4.3e-29 101.9 9.8 4.9 2 2 3 5 5 5 2 Type-1V conjugative transfer system mating pair stabilisation Staphylokinase PF02821.16 pCP009044_00011 - 0.075 13.5 5.2 2.6 8.5 1.5 2.1 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family HTH_19 PF12844.7 pCP009044_00013 - 9.4e-08 32.0 0.6 3.6e-07 30.1 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 pCP009044_00013 - 3.1e-06 27.1 0.2 5.9e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pCP009044_00013 - 0.0061 17.0 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Phage_CI_repr PF07022.13 pCP009044_00013 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_25 PF13413.6 pCP009044_00013 - 0.014 15.2 0.0 0.028 14.3 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Pup PF05639.11 pCP009044_00013 - 0.02 15.8 0.3 0.038 14.9 0.3 1.4 1 0 0 1 1 1 0 Pup-like protein Nbl1_Borealin_N PF10444.9 pCP009044_00013 - 0.047 13.3 2.8 0.37 10.5 0.2 2.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF16 PF01519.16 pCP009044_00013 - 0.16 12.5 3.8 0.41 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-ACC PF17848.1 pCP009044_00016 - 0.0036 17.3 4.1 0.8 9.8 0.4 2.6 2 0 0 2 2 2 2 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 pCP009044_00016 - 0.0069 15.8 2.9 1.8 8.1 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 pCP009044_00016 - 0.0087 15.6 2.4 0.77 9.3 0.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding tRNA-synt_1g PF09334.11 pCP009044_00016 - 0.021 13.6 0.7 0.024 13.4 0.7 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-ISL3 PF14690.6 pCP009044_00016 - 0.023 15.4 1.2 0.26 12.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 pCP009044_00016 - 0.031 14.4 0.3 5.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.6 pCP009044_00016 - 0.032 14.0 1.0 6.4 6.6 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pCP009044_00016 - 0.064 13.5 1.4 7.3 6.9 0.0 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Elf1 PF05129.13 pCP009044_00016 - 0.09 12.8 2.1 0.075 13.1 0.9 1.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.6 pCP009044_00016 - 0.09 13.7 1.8 19 6.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3 PF13878.6 pCP009044_00016 - 0.1 12.4 1.6 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF4379 PF14311.6 pCP009044_00016 - 0.13 12.6 6.2 0.49 10.8 1.4 2.6 2 1 0 2 2 2 0 Probable Zinc-ribbon domain DUF35_N PF12172.8 pCP009044_00016 - 0.18 11.7 2.4 5.2 7.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 pCP009044_00016 - 0.22 11.3 4.3 8.6 6.2 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 pCP009044_00016 - 0.25 11.3 4.7 7 6.7 0.2 2.3 1 1 1 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 pCP009044_00016 - 0.25 11.4 2.4 1.2 9.2 2.4 1.9 1 1 0 1 1 1 0 CpXC protein Zn_Tnp_IS91 PF14319.6 pCP009044_00016 - 0.36 10.9 4.1 1 9.4 0.4 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain Zn_Tnp_IS1595 PF12760.7 pCP009044_00016 - 0.66 10.0 5.5 5.1 7.1 3.1 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Phage_integrase PF00589.22 pCP009044_00017 - 4.8e-23 81.8 0.1 8.8e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 pCP009044_00017 - 0.0021 18.5 8.6 0.2 12.1 0.7 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 pCP009044_00017 - 0.0042 17.4 0.3 0.023 15.0 0.3 2.2 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain TSNAXIP1_N PF15739.5 pCP009044_00017 - 0.11 12.8 1.6 0.29 11.5 1.3 1.8 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Phage_int_SAM_3 PF14659.6 pCP009044_00017 - 0.99 9.7 6.9 0.67 10.3 0.7 3.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF1566 PF07603.11 pCP009044_00018 - 0.0015 18.9 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) DUF433 PF04255.14 pCP009044_00019 - 0.047 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Toxin_YhaV PF11663.8 pCP009044_00019 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system WGR PF05406.15 pCP009044_00023 - 6.7e-07 29.3 0.3 8.8e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 WGR domain DUF3951 PF13131.6 pCP009044_00027 - 0.048 13.9 0.2 0.048 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF4064 PF13273.6 pCP009044_00028 - 1.1 9.6 10.9 2.4e+02 2.1 10.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2929 PF11151.8 pCP009044_00028 - 2.9 8.3 8.4 0.12 12.7 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2929) HD_2 PF12917.7 pCP009044_00029 - 0.00032 20.5 0.1 0.00069 19.4 0.1 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme CDT1 PF08839.11 pCP009044_00031 - 0.089 13.1 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like DUF1351 PF07083.11 pCP009044_00032 - 3.8e-24 85.6 8.0 3.8e-24 85.6 8.0 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1351) DUF4337 PF14235.6 pCP009044_00032 - 0.96 9.5 5.4 2.1 8.4 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Allexi_40kDa PF05549.11 pCP009044_00032 - 1.6 8.2 6.9 0.15 11.5 1.9 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein KIP1 PF07765.12 pCP009044_00032 - 8.7 6.5 9.0 0.72 10.0 1.3 2.5 2 0 0 2 2 2 0 KIP1-like protein LBR_tudor PF09465.10 pCP009044_00033 - 0.036 13.9 0.2 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain zf-B_box PF00643.24 pCP009044_00034 - 0.006 16.7 13.5 0.0062 16.7 7.5 2.3 2 0 0 2 2 2 1 B-box zinc finger FYVE PF01363.21 pCP009044_00034 - 0.026 14.6 6.7 0.067 13.3 6.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger DUF4428 PF14471.6 pCP009044_00034 - 0.069 13.1 0.1 0.069 13.1 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.13 pCP009044_00034 - 0.19 11.6 12.5 1.7 8.6 1.0 2.4 2 0 0 2 2 2 0 ClpX C4-type zinc finger Gin PF10764.9 pCP009044_00034 - 0.24 11.4 10.0 3.5 7.7 0.2 2.7 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_2 PF13639.6 pCP009044_00034 - 0.34 11.3 9.3 7.6 7.0 7.4 2.4 1 1 1 2 2 2 0 Ring finger domain zf-CHY PF05495.12 pCP009044_00034 - 0.35 11.4 10.0 0.22 12.0 1.4 2.3 1 1 1 2 2 2 0 CHY zinc finger Ac81 PF05820.11 pCP009044_00034 - 0.92 9.0 4.8 3.3 7.2 2.3 2.1 2 0 0 2 2 2 0 Baculoviridae AC81 zf-C3HC4_3 PF13920.6 pCP009044_00034 - 1.2 9.0 10.5 9.4 6.2 5.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 pCP009044_00034 - 1.5 8.7 13.2 2.1 8.2 6.1 2.5 1 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Tnp_zf-ribbon_2 PF13842.6 pCP009044_00034 - 8.2 7.3 10.6 2.7 8.8 5.2 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-ACC PF17848.1 pCP009044_00037 - 0.098 12.8 3.8 8 6.6 0.5 3.0 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 pCP009044_00037 - 6.7 6.8 10.9 31 4.7 10.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Toprim_2 PF13155.6 pCP009044_00039 - 1e-14 54.7 0.0 2.7e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Toprim-like Toprim_3 PF13362.6 pCP009044_00039 - 1.6e-08 34.8 0.0 3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.20 pCP009044_00039 - 4.3e-07 29.7 0.3 9.7e-07 28.5 0.3 1.6 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_4 PF13662.6 pCP009044_00039 - 0.0096 16.4 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF3854 PF12965.7 pCP009044_00039 - 0.023 14.7 0.2 0.29 11.1 0.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) N6_N4_Mtase PF01555.18 pCP009044_00040 - 2.4e-05 24.2 0.4 0.042 13.5 0.2 2.1 2 0 0 2 2 2 2 DNA methylase DpnI_C PF17726.1 pCP009044_00040 - 0.00013 22.0 0.3 0.00036 20.6 0.3 1.7 1 0 0 1 1 1 1 Dam-replacing HTH domain zf-BED PF02892.15 pCP009044_00041 - 0.042 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 BED zinc finger DUF4258 PF14076.6 pCP009044_00045 - 0.069 13.5 0.3 0.81 10.1 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) Methyltransf_23 PF13489.6 pCP009044_00045 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MPTase-PolyVal PF18818.1 pCP009044_00046 - 8.2e-48 161.6 0.0 1.2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase superfamily domain DUF1738 PF08401.11 pCP009044_00046 - 1.1e-33 116.1 0.1 1.9e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) EpmC PF04315.12 pCP009044_00046 - 0.00047 19.9 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P hydroxylase Tox-MPTase3 PF15639.6 pCP009044_00046 - 0.0042 16.9 0.1 0.0092 15.8 0.1 1.5 1 0 0 1 1 1 1 Metallopeptidase toxin 3 DUF4127 PF13552.6 pCP009044_00046 - 0.021 13.5 0.1 0.028 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) GP88 PF17338.2 pCP009044_00046 - 0.022 14.2 0.1 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 Gene product 88 Fucose_iso_N2 PF07882.12 pCP009044_00047 - 0.0057 16.2 0.8 0.01 15.5 0.3 1.6 1 1 1 2 2 2 1 L-fucose isomerase, second N-terminal domain RNA_pol_Rpb8 PF03870.15 pCP009044_00047 - 0.056 13.6 0.1 0.076 13.2 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb8 s48_45 PF07422.13 pCP009044_00047 - 0.082 13.5 0.8 0.28 11.8 0.1 1.8 1 1 0 2 2 2 0 Sexual stage antigen s48/45 domain RecT PF03837.14 pCP009044_00048 - 1.2e-36 126.1 0.3 4.5e-36 124.2 0.0 1.8 1 1 1 2 2 2 1 RecT family Cas_Cas4 PF01930.17 pCP009044_00051 - 1.6e-06 28.3 0.2 1.6e-06 28.3 0.2 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 pCP009044_00051 - 8.1e-05 22.7 1.2 0.00013 22.0 0.2 1.9 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Nsp1_C PF05064.13 pCP009044_00051 - 0.0026 17.5 0.5 0.0026 17.5 0.5 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region GrpE PF01025.19 pCP009044_00051 - 0.011 15.4 1.7 0.011 15.4 1.7 2.3 2 0 0 2 2 2 0 GrpE CENP-F_leu_zip PF10473.9 pCP009044_00051 - 0.035 14.1 9.6 0.043 13.8 3.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 pCP009044_00051 - 0.058 12.7 1.6 0.1 11.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CdvA PF18822.1 pCP009044_00051 - 0.2 11.5 8.1 1.2 8.9 1.2 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF615 PF04751.14 pCP009044_00051 - 1.7 8.6 7.9 0.17 11.8 1.5 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF615) CHASE3 PF05227.13 pCP009044_00051 - 6.7 6.6 8.3 1.5 8.7 0.7 2.7 3 0 0 3 3 3 0 CHASE3 domain SSB PF00436.25 pCP009044_00053 - 1.8e-29 101.9 0.2 3.2e-29 101.0 0.2 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Pex14_N PF04695.13 pCP009044_00053 - 0.29 11.8 7.3 0.46 11.1 7.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Toxin-JAB1 PF15659.6 pCP009044_00054 - 0.088 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 JAB-like toxin 1 Dus PF01207.17 pCP009044_00058 - 0.03 13.4 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) SLT PF01464.20 pCP009044_00059 - 4.6e-19 68.2 0.0 6.1e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 pCP009044_00059 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family DUF480 PF04337.12 pCP009044_00060 - 0.0017 18.4 0.1 0.0019 18.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF480 RdRP_1 PF00680.20 pCP009044_00060 - 0.027 13.0 0.1 0.03 12.8 0.1 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF3267 PF11667.8 pCP009044_00061 - 0.042 14.1 8.6 0.053 13.8 5.1 2.6 1 1 1 2 2 2 0 Putative zincin peptidase Peptidase_M50B PF13398.6 pCP009044_00061 - 0.14 11.8 7.8 2.4 7.7 7.7 2.3 1 1 0 1 1 1 0 Peptidase M50B-like GGDEF PF00990.21 pCP009044_00062 - 5e-34 117.4 0.6 1.1e-33 116.2 0.6 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HD PF01966.22 pCP009044_00062 - 2.7e-05 24.4 0.4 2.7e-05 24.4 0.4 3.0 4 0 0 4 4 4 1 HD domain SporV_AA PF12164.8 pCP009044_00062 - 0.039 14.3 4.1 0.057 13.8 0.2 3.1 3 0 0 3 3 3 0 Stage V sporulation protein AA STAR_dimer PF16544.5 pCP009044_00062 - 0.044 13.4 0.3 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Toxin-deaminase PF14424.6 pCP009044_00062 - 0.045 13.9 0.6 0.045 13.9 0.6 3.2 3 0 0 3 3 3 0 The BURPS668_1122 family of deaminases Stealth_CR4 PF17103.5 pCP009044_00062 - 0.081 12.8 0.1 6.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 SurA_N_2 PF13623.6 pCP009044_00062 - 4.1 7.3 12.7 2.3 8.1 0.5 3.8 4 0 0 4 4 4 0 SurA N-terminal domain TrwB_AAD_bind PF10412.9 pCP009044_00063 - 5.1e-16 58.6 0.0 1.7e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 pCP009044_00063 - 2e-11 43.4 0.6 2.8e-11 42.9 0.6 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP009044_00063 - 4.3e-10 39.7 0.0 8.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG DUF87 PF01935.17 pCP009044_00063 - 0.0005 20.2 0.3 0.0045 17.1 0.3 2.3 1 1 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 pCP009044_00063 - 0.0014 17.9 0.0 0.0035 16.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 pCP009044_00063 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 pCP009044_00063 - 0.0022 18.0 0.0 0.01 15.8 0.0 2.1 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea DUF853 PF05872.12 pCP009044_00063 - 0.0045 15.6 0.0 0.0082 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_10 PF12846.7 pCP009044_00063 - 0.0054 15.7 0.1 0.12 11.2 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.6 pCP009044_00063 - 0.011 16.1 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 pCP009044_00063 - 0.095 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 pCP009044_00063 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain HD_5 PF13487.6 pCP009044_00064 - 4.6e-06 26.8 0.0 8.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 HD domain CLP_protease PF00574.23 pCP009044_00066 - 0.15 12.0 0.3 0.3 10.9 0.3 1.5 1 0 0 1 1 1 0 Clp protease GA-like PF17573.2 pCP009044_00067 - 0.035 14.0 0.4 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 GA-like domain Orthopox_A49R PF06489.11 pCP009044_00067 - 0.16 12.2 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A49R protein HTH_3 PF01381.22 pCP009044_00068 - 2.7e-14 52.9 0.0 3.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pCP009044_00068 - 7.9e-13 48.2 0.0 8.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 pCP009044_00068 - 8.3e-08 32.5 0.0 8.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 pCP009044_00068 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_CI_repr PF07022.13 pCP009044_00068 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.3 1 1 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain Pou PF00157.17 pCP009044_00068 - 0.026 14.5 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_37 PF13744.6 pCP009044_00068 - 0.047 13.7 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 pCP009044_00068 - 0.055 13.6 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_23 PF13384.6 pCP009044_00068 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain WYL_3 PF18488.1 pCP009044_00068 - 0.081 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 WYL domain YdaS_antitoxin PF15943.5 pCP009044_00068 - 0.1 12.4 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SNase PF00565.17 pCP009044_00069 - 4.4e-17 62.5 0.1 5.5e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue AAA_25 PF13481.6 pCP009044_00072 - 5.9e-17 61.9 0.0 9.6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB PF00772.21 pCP009044_00072 - 1.3e-06 28.4 0.3 2.9e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain Thioredoxin_2 PF13098.6 pCP009044_00073 - 2.7e-05 24.6 0.2 0.00022 21.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 pCP009044_00073 - 3.2e-05 24.0 0.0 4.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 pCP009044_00073 - 0.00012 22.1 0.1 0.0003 20.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF255 VSG_B PF13206.6 pCP009044_00074 - 0.018 14.3 0.9 0.018 14.3 0.9 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain HSCB_C PF07743.13 pCP009044_00074 - 0.019 15.5 2.0 0.021 15.3 2.0 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain YtxH PF12732.7 pCP009044_00074 - 0.034 14.7 0.1 0.045 14.3 0.1 1.2 1 0 0 1 1 1 0 YtxH-like protein TrbC_Ftype PF09673.10 pCP009044_00075 - 9.3e-17 61.1 0.0 2.2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein DUF3388 PF11868.8 pCP009044_00075 - 0.035 13.4 0.2 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) EAL PF00563.20 pCP009044_00076 - 3.4e-28 98.8 0.0 4.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 EAL domain TraU PF06834.11 pCP009044_00077 - 8.2e-100 334.0 0.4 9.4e-100 333.8 0.4 1.0 1 0 0 1 1 1 1 TraU protein TraF PF13728.6 pCP009044_00079 - 3e-30 105.7 10.7 3.5e-30 105.5 10.7 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein KaiB PF07689.12 pCP009044_00079 - 0.055 13.2 0.2 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 KaiB domain ASC PF00858.24 pCP009044_00079 - 0.72 8.7 5.6 0.91 8.4 5.6 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TraG_N PF07916.11 pCP009044_00080 - 1.7e-51 175.6 17.8 1.7e-51 175.6 17.8 2.8 3 0 0 3 3 3 1 TraG-like protein, N-terminal region CdiI_2 PF18593.1 pCP009044_00080 - 0.18 12.5 0.8 11 6.7 0.4 2.9 1 1 1 2 2 2 0 CdiI immunity protein YfhO PF09586.10 pCP009044_00081 - 0.016 13.5 2.6 0.018 13.3 2.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1189 PF06691.11 pCP009044_00081 - 0.017 14.7 2.0 0.02 14.5 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) Herpes_LMP1 PF05297.11 pCP009044_00081 - 0.068 12.4 3.2 0.083 12.1 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RHH_3 PF12651.7 pCP009044_00082 - 0.0013 18.6 1.3 0.0028 17.6 0.8 1.8 2 0 0 2 2 2 1 Ribbon-helix-helix domain DUF5123 PF17161.4 pCP009044_00082 - 0.058 14.5 0.9 0.068 14.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5123) UvrB_inter PF17757.1 pCP009044_00083 - 0.052 13.7 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 UvrB interaction domain ALP_N PF17989.1 pCP009044_00085 - 5.9e-15 55.7 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Actin like proteins N terminal domain FtsA PF14450.6 pCP009044_00085 - 0.00012 22.5 0.1 0.031 14.7 0.0 2.4 2 0 0 2 2 2 2 Cell division protein FtsA DUF2800 PF10926.8 pCP009044_00085 - 0.12 11.6 0.1 0.37 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) DBR1 PF05011.13 pCP009044_00086 - 0.0072 16.8 1.1 0.0081 16.6 1.1 1.1 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain DUF3400 PF11880.8 pCP009044_00087 - 0.1 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) DUF2786 PF10979.8 pCP009044_00087 - 0.18 11.8 1.3 0.37 10.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Acetyltransf_9 PF13527.7 pCP009044_00088 - 0.099 12.7 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ring_hydroxyl_B PF00866.18 pCP009044_00089 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit SSXT PF05030.12 pCP009044_00090 - 0.022 14.4 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) NMT PF01233.19 pCP009044_00090 - 0.092 12.6 0.6 0.11 12.3 0.6 1.5 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain bZIP_2 PF07716.15 pCP009044_00090 - 0.13 12.4 0.3 0.13 12.4 0.3 1.6 2 0 0 2 2 2 0 Basic region leucine zipper BfiI_DBD PF18243.1 pCP009044_00090 - 0.17 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain AbiH PF14253.6 pCP009044_00092 - 0.023 14.6 1.3 0.03 14.2 1.3 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH PH_12 PF16457.5 pCP009044_00092 - 0.1 13.1 0.2 0.83 10.2 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain ANT PF03374.14 pCP009044_00093 - 0.041 14.2 0.0 0.045 14.1 0.0 1.1 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain PhetRS_B1 PF18262.1 pCP009044_00093 - 0.062 13.5 0.2 0.076 13.2 0.2 1.1 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain HTH_28 PF13518.6 pCP009044_00093 - 0.1 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TMEM51 PF15345.6 pCP009044_00094 - 0.11 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_19 PF13245.6 pCP009044_00095 - 2.8e-13 50.4 0.0 7.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 pCP009044_00095 - 4.2e-13 49.5 7.9 3.8e-08 33.2 2.3 3.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 pCP009044_00095 - 3.2e-12 46.5 2.8 1.2e-11 44.7 1.9 2.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 pCP009044_00095 - 5.1e-09 35.8 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 pCP009044_00095 - 1.1e-08 35.1 0.7 0.0055 16.5 0.0 3.5 2 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 pCP009044_00095 - 0.00014 21.6 0.1 0.0023 17.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 pCP009044_00095 - 0.00093 18.7 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 pCP009044_00095 - 0.011 15.7 5.8 0.027 14.5 1.5 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 pCP009044_00095 - 0.017 15.0 0.3 6.1 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain OMPdecase PF00215.24 pCP009044_00095 - 0.11 12.1 0.1 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family RNase_T PF00929.24 pCP009044_00097 - 0.036 14.6 0.1 0.04 14.4 0.1 1.1 1 0 0 1 1 1 0 Exonuclease DUF1722 PF08349.11 pCP009044_00098 - 0.11 12.8 0.0 0.13 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF460 PF04312.13 pCP009044_00100 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF5643 PF18705.1 pCP009044_00103 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5643) MrpF_PhaF PF04066.13 pCP009044_00106 - 0.01 16.2 1.3 0.01 16.2 1.3 2.5 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) UPF0242 PF06785.11 pCP009044_00106 - 0.026 14.6 1.1 0.028 14.5 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UPF0016 PF01169.19 pCP009044_00106 - 0.039 14.3 7.1 0.089 13.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein family UPF0016 TrbC PF04956.13 pCP009044_00106 - 1.2 9.4 11.4 1.3 9.3 11.4 1.0 1 0 0 1 1 1 0 TrbC/VIRB2 family TraL PF07178.11 pCP009044_00107 - 2.4e-12 47.2 1.0 2.7e-12 47.0 1.0 1.1 1 0 0 1 1 1 1 TraL protein ThrE PF06738.12 pCP009044_00107 - 0.024 14.0 0.3 0.026 13.9 0.3 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter TraE PF05309.11 pCP009044_00108 - 2e-34 118.5 1.7 2.5e-34 118.3 1.7 1.0 1 0 0 1 1 1 1 TraE protein MadM PF03818.13 pCP009044_00108 - 0.047 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit TraK PF06586.11 pCP009044_00109 - 9.5e-24 84.4 3.7 3.6e-23 82.5 3.7 1.7 1 1 0 1 1 1 1 TraK protein NusG_II PF07009.11 pCP009044_00109 - 0.32 11.2 4.5 0.13 12.4 0.6 2.2 2 1 0 2 2 2 0 NusG domain II TrbI PF03743.14 pCP009044_00110 - 3.5e-33 115.0 1.1 4.8e-33 114.6 1.1 1.2 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein Bap31_Bap29_C PF18035.1 pCP009044_00110 - 0.0036 17.3 1.3 0.011 15.7 1.3 1.8 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 pCP009044_00110 - 0.0052 17.0 2.6 0.01 16.0 2.6 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 pCP009044_00110 - 0.0093 16.1 2.9 0.027 14.6 2.9 1.8 1 0 0 1 1 1 1 bZIP transcription factor UPF0242 PF06785.11 pCP009044_00110 - 0.046 13.8 1.5 0.083 13.0 1.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 pCP009044_00110 - 0.094 12.5 3.1 0.23 11.2 3.1 1.6 1 0 0 1 1 1 0 Septum formation initiator FAD-SLDH PF12318.8 pCP009044_00110 - 0.13 12.3 0.8 0.26 11.3 0.2 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase YabA PF06156.13 pCP009044_00110 - 0.19 12.4 1.5 0.48 11.1 1.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Thioredoxin_2 PF13098.6 pCP009044_00111 - 3.3e-16 59.7 0.1 6.6e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 pCP009044_00111 - 1.3e-07 30.9 0.1 3e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 pCP009044_00111 - 1.3e-06 28.7 2.0 0.0038 17.4 0.3 3.2 1 1 1 2 2 2 2 Thioredoxin DSBA PF01323.20 pCP009044_00111 - 1.3e-06 28.3 0.3 0.01 15.6 0.1 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 pCP009044_00111 - 0.0039 17.4 0.3 0.038 14.2 0.1 2.4 2 0 0 2 2 2 1 Glutaredoxin ATPgrasp_YheCD PF14398.6 pCP009044_00111 - 0.0088 15.3 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp TraF PF13728.6 pCP009044_00111 - 0.013 15.3 0.1 6.2 6.6 0.0 2.4 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 pCP009044_00111 - 0.021 14.9 1.1 9.8 6.3 0.4 2.8 2 1 1 3 3 3 0 Thioredoxin domain Thioredoxin_8 PF13905.6 pCP009044_00111 - 0.04 14.2 0.4 0.18 12.1 0.4 2.1 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.6 pCP009044_00111 - 0.071 12.8 0.4 6.9 6.3 0.4 2.3 1 1 1 2 2 2 0 Thioredoxin TraV PF09676.10 pCP009044_00112 - 0.0043 18.0 5.3 0.0097 16.9 5.2 1.8 1 1 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) SH3_4 PF06347.13 pCP009044_00112 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_3 PF08239.11 pCP009044_00112 - 0.013 15.7 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Transketolase_N PF00456.21 pCP009044_00112 - 0.049 12.6 0.3 0.085 11.8 0.3 1.5 1 1 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Herpes_glycop_D PF01537.17 pCP009044_00112 - 0.052 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain SH3_3 PF08239.11 pCP009044_00113 - 5.6e-05 23.3 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain ADIP PF11559.8 pCP009044_00113 - 0.0013 18.8 3.7 0.0023 18.0 3.7 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 pCP009044_00113 - 0.0038 17.1 1.5 0.0054 16.6 1.5 1.3 1 0 0 1 1 1 1 Sec34-like family CLZ PF16526.5 pCP009044_00113 - 0.0068 16.7 4.4 1.8 9.0 0.0 2.4 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SMC_ScpB PF04079.16 pCP009044_00113 - 0.0085 15.7 1.4 0.013 15.2 1.4 1.3 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB V_ATPase_I PF01496.19 pCP009044_00113 - 0.022 12.7 3.4 0.025 12.5 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 pCP009044_00113 - 0.03 14.7 0.6 0.045 14.1 0.6 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Cob_adeno_trans PF01923.18 pCP009044_00113 - 0.041 14.0 1.6 0.067 13.3 1.6 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Spectrin PF00435.21 pCP009044_00113 - 0.046 14.2 2.7 0.11 13.0 2.7 1.6 1 0 0 1 1 1 0 Spectrin repeat M PF02370.16 pCP009044_00113 - 0.072 13.7 6.6 0.31 11.7 6.6 2.2 1 0 0 1 1 1 0 M protein repeat DUF1319 PF07028.11 pCP009044_00113 - 0.11 12.7 3.3 0.23 11.7 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) TolA_bind_tri PF16331.5 pCP009044_00113 - 0.16 12.0 2.2 0.53 10.4 1.7 2.0 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF272 PF03312.15 pCP009044_00113 - 0.2 11.9 3.6 1.6 9.0 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF272) FlaC_arch PF05377.11 pCP009044_00113 - 0.24 11.8 4.0 2 8.9 1.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 pCP009044_00113 - 0.27 11.7 2.6 0.55 10.7 1.7 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 pCP009044_00113 - 0.67 9.9 6.4 0.83 9.6 3.3 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 pCP009044_00113 - 1.6 9.4 7.4 2.7 8.7 7.4 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Swi5 PF07061.11 pCP009044_00113 - 5.2 7.2 8.9 1.3 9.1 3.1 2.5 2 1 1 3 3 3 0 Swi5 Peptidase_C39 PF03412.15 pCP010073_00002 - 9e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pCP010073_00002 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 pCP010073_00002 - 0.085 13.4 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family Relaxase PF03432.14 pCP010073_00004 - 1.6e-09 37.8 6.2 1.6e-09 37.8 6.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP010073_00005 - 0.00011 22.1 5.7 0.067 13.2 0.7 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP010073_00005 - 0.049 13.8 1.8 0.069 13.3 1.4 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP010073_00005 - 0.28 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP010073_00005 - 0.3 11.4 5.9 1.4 9.2 2.0 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP010073_00005 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pCP010073_00006 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pCP010073_00006 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pCP010073_00006 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pCP010073_00008 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP010073_00009 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP010073_00009 - 0.087 12.8 0.3 0.38 10.7 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP010073_00009 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP010073_00009 - 0.2 12.3 4.2 1.4 9.5 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP010073_00010 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) CCDC50_N PF15295.6 pCP010073_00010 - 0.011 15.9 2.0 0.013 15.6 2.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus BAR_3 PF16746.5 pCP010073_00010 - 0.021 14.6 1.6 0.023 14.4 1.6 1.0 1 0 0 1 1 1 0 BAR domain of APPL family Uteroglobin PF01099.17 pCP010073_00010 - 2.4 8.6 5.7 12 6.3 0.7 2.2 1 1 1 2 2 2 0 Uteroglobin family Sdh_cyt PF01127.22 pCP010073_00011 - 0.00091 19.3 0.8 0.0011 19.0 0.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pCP010073_00011 - 0.13 12.6 3.1 0.17 12.2 3.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2207 PF09972.9 pCP010073_00011 - 0.58 8.9 2.2 0.6 8.8 2.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2633 PF11119.8 pCP010073_00011 - 0.58 10.1 3.8 2.3 8.2 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP010073_00013 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP010073_00014 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP010073_00015 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP010073_00015 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP010073_00015 - 0.0022 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP010073_00015 - 0.0088 15.4 0.0 0.058 12.7 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP010073_00015 - 0.014 15.8 0.2 0.33 11.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP010073_00015 - 0.21 11.6 2.3 1.2 9.3 2.3 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP010073_00015 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pCP010073_00016 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP010073_00016 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP010073_00016 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pCP010073_00017 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pCP010073_00019 - 1.5e-14 54.0 8.5 1.6e-14 53.9 8.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP010073_00019 - 0.056 13.3 4.3 0.073 12.9 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP010073_00020 - 3.6e-49 167.7 0.3 9e-49 166.4 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP010073_00020 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP010073_00020 - 3.8e-07 29.4 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP010073_00020 - 0.024 14.7 4.5 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pCP010073_00021 - 6.9e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP010073_00021 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP010073_00021 - 0.031 13.9 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP010073_00021 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP010073_00021 - 0.56 10.3 5.4 7.7 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 Phage_pRha PF09669.10 pCP010073_00022 - 4.3e-24 84.9 0.3 6.9e-24 84.2 0.3 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pCP010073_00023 - 0.075 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP010073_00023 - 0.15 10.6 14.4 0.009 14.7 7.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP010073_00023 - 0.95 9.6 11.6 0.062 13.5 3.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP010073_00023 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF465 PF04325.13 pCP010073_00023 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP010073_00024 - 1.7e-25 89.0 0.1 2.2e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP010073_00025 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP010073_00025 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP010073_00025 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP010073_00025 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP010073_00026 - 5.7e-28 98.7 13.6 7.8e-28 98.2 13.6 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP010073_00026 - 0.0056 16.8 1.3 0.024 14.8 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP010073_00026 - 0.0092 16.7 6.0 0.0092 16.7 6.0 2.4 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP010073_00026 - 0.1 13.3 3.5 0.077 13.7 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pCP010073_00026 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pCP010073_00026 - 3.1 8.3 8.6 9.9 6.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 pCP010073_00027 - 2.3e-30 106.0 31.8 2.3e-30 106.0 31.8 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP010073_00027 - 0.17 11.7 1.7 0.55 10.1 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP010073_00027 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP010073_00028 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP010073_00028 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP010073_00029 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP010073_00029 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP010073_00030 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP010073_00030 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP010073_00031 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP010073_00031 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP010073_00032 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP010073_00032 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP010073_00032 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP010073_00032 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP010073_00032 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP010073_00032 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP010073_00032 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP010073_00032 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP010073_00032 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP010073_00032 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP010073_00032 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP010073_00032 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP010073_00032 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP010073_00032 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP010073_00032 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP010073_00032 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP010073_00032 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP010073_00032 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP010073_00032 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP010073_00032 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP010073_00032 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP010073_00032 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP010073_00032 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP010073_00032 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP010073_00032 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP010073_00032 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP010073_00032 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP010073_00032 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP010073_00032 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP010073_00032 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP010073_00032 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP010073_00033 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP010073_00033 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP010073_00033 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP010073_00033 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP010073_00034 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP010073_00034 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP010073_00034 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP010073_00035 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP010073_00036 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP010073_00036 - 0.077 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP010073_00036 - 0.74 9.8 5.2 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP010073_00038 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP010073_00039 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP010073_00039 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP010073_00039 - 1.7e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP010073_00039 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP010073_00039 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP010073_00039 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pCP010073_00039 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP010073_00039 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pCP010073_00039 - 0.088 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 pCP010073_00039 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP010073_00039 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP010073_00039 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP010073_00039 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP010073_00039 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP010073_00039 - 6.9 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP010073_00039 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP010073_00040 - 2.7e-05 24.1 2.2 7.5e-05 22.6 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP010073_00040 - 0.016 15.2 4.6 0.14 12.1 4.6 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP010073_00042 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP010073_00042 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP010073_00042 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP010073_00042 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP010073_00042 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP010073_00042 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP010073_00042 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP010073_00042 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP010073_00042 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 pCP010073_00043 - 1.5e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP010073_00043 - 3.5e-06 27.0 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pCP010073_00043 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pCP010073_00043 - 0.088 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication APH PF01636.23 pCP010073_00044 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP010073_00044 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP010073_00044 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP010073_00044 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP010073_00044 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP010073_00044 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP010073_00045 - 1.6e-24 87.2 0.0 2.1e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Lip_prot_lig_C PF10437.9 pCP010073_00046 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP010073_00046 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP010073_00047 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pCP010073_00048 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP010073_00048 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP010073_00048 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP010073_00048 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP010073_00048 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP010073_00048 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP010073_00048 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pCP010073_00049 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP010073_00049 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP010073_00049 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP010073_00049 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP010073_00049 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP010073_00050 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP010073_00050 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP010073_00051 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP010073_00051 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP010073_00051 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP010073_00051 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP010073_00051 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP010073_00052 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP010073_00053 - 2e-16 59.6 0.8 6e-16 58.1 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP010073_00053 - 5.5e-08 33.0 8.4 5.5e-08 33.0 8.4 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP010073_00053 - 9.1e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP010073_00053 - 1.1e-05 25.3 1.8 0.0012 18.7 0.3 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP010073_00053 - 3.8e-05 24.1 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase HTH_3 PF01381.22 pCP010073_00054 - 4.7e-06 26.6 0.0 0.00046 20.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 pCP010073_00054 - 1.1e-05 25.3 0.2 0.011 15.7 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain Phage_CI_repr PF07022.13 pCP010073_00054 - 0.00047 20.2 0.0 0.081 13.0 0.0 2.5 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_23 PF13384.6 pCP010073_00054 - 0.0075 16.0 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 pCP010073_00054 - 0.0076 15.8 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pCP010073_00054 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP010073_00054 - 0.022 14.6 0.1 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_26 PF13443.6 pCP010073_00054 - 0.045 14.2 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 pCP010073_00054 - 0.1 12.8 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 pCP010073_00054 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_AlpA PF05930.12 pCP010073_00054 - 0.15 11.9 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Sigma70_r4_2 PF08281.12 pCP010073_00054 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Peptidase_C39 PF03412.15 pCP010302_00002 - 9e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pCP010302_00002 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 pCP010302_00002 - 0.085 13.4 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family Relaxase PF03432.14 pCP010302_00004 - 1.6e-09 37.8 6.2 1.6e-09 37.8 6.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP010302_00005 - 0.00011 22.1 5.7 0.067 13.2 0.7 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP010302_00005 - 0.049 13.8 1.8 0.069 13.3 1.4 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP010302_00005 - 0.28 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP010302_00005 - 0.3 11.4 5.9 1.4 9.2 2.0 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP010302_00005 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pCP010302_00006 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pCP010302_00006 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pCP010302_00006 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pCP010302_00008 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP010302_00009 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP010302_00009 - 0.087 12.8 0.3 0.38 10.7 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP010302_00009 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP010302_00009 - 0.2 12.3 4.2 1.4 9.5 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP010302_00010 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) CCDC50_N PF15295.6 pCP010302_00010 - 0.011 15.9 2.0 0.013 15.6 2.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus BAR_3 PF16746.5 pCP010302_00010 - 0.021 14.6 1.6 0.023 14.4 1.6 1.0 1 0 0 1 1 1 0 BAR domain of APPL family Uteroglobin PF01099.17 pCP010302_00010 - 2.4 8.6 5.7 12 6.3 0.7 2.2 1 1 1 2 2 2 0 Uteroglobin family Sdh_cyt PF01127.22 pCP010302_00011 - 0.00091 19.3 0.8 0.0011 19.0 0.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pCP010302_00011 - 0.13 12.6 3.1 0.17 12.2 3.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2207 PF09972.9 pCP010302_00011 - 0.58 8.9 2.2 0.6 8.8 2.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2633 PF11119.8 pCP010302_00011 - 0.58 10.1 3.8 2.3 8.2 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP010302_00013 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP010302_00014 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP010302_00015 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP010302_00015 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP010302_00015 - 0.0022 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP010302_00015 - 0.0088 15.4 0.0 0.058 12.7 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP010302_00015 - 0.014 15.8 0.2 0.33 11.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP010302_00015 - 0.21 11.6 2.3 1.2 9.3 2.3 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP010302_00015 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pCP010302_00016 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP010302_00016 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP010302_00016 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pCP010302_00017 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pCP010302_00019 - 1.5e-14 54.0 8.5 1.6e-14 53.9 8.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP010302_00019 - 0.056 13.3 4.3 0.073 12.9 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP010302_00020 - 3.6e-49 167.7 0.3 9e-49 166.4 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP010302_00020 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP010302_00020 - 3.8e-07 29.4 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP010302_00020 - 0.024 14.7 4.5 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pCP010302_00021 - 6.9e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP010302_00021 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP010302_00021 - 0.031 13.9 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP010302_00021 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP010302_00021 - 0.56 10.3 5.4 7.7 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 Phage_pRha PF09669.10 pCP010302_00022 - 4.3e-24 84.9 0.3 6.9e-24 84.2 0.3 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pCP010302_00023 - 0.075 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP010302_00023 - 0.15 10.6 14.4 0.009 14.7 7.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP010302_00023 - 0.95 9.6 11.6 0.062 13.5 3.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP010302_00023 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF465 PF04325.13 pCP010302_00023 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP010302_00024 - 1.7e-25 89.0 0.1 2.2e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP010302_00025 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP010302_00025 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP010302_00025 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP010302_00025 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP010302_00026 - 5.7e-28 98.7 13.6 7.8e-28 98.2 13.6 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP010302_00026 - 0.0056 16.8 1.3 0.024 14.8 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP010302_00026 - 0.0092 16.7 6.0 0.0092 16.7 6.0 2.4 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP010302_00026 - 0.1 13.3 3.5 0.077 13.7 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pCP010302_00026 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pCP010302_00026 - 3.1 8.3 8.6 9.9 6.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 pCP010302_00027 - 2.3e-30 106.0 31.8 2.3e-30 106.0 31.8 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP010302_00027 - 0.17 11.7 1.7 0.55 10.1 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP010302_00027 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP010302_00028 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP010302_00028 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP010302_00029 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP010302_00029 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP010302_00030 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP010302_00030 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP010302_00031 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP010302_00031 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP010302_00032 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP010302_00032 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP010302_00032 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP010302_00032 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP010302_00032 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP010302_00032 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP010302_00032 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP010302_00032 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP010302_00032 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP010302_00032 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP010302_00032 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP010302_00032 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP010302_00032 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP010302_00032 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP010302_00032 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP010302_00032 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP010302_00032 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP010302_00032 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP010302_00032 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP010302_00032 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP010302_00032 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP010302_00032 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP010302_00032 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP010302_00032 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP010302_00032 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP010302_00032 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP010302_00032 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP010302_00032 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP010302_00032 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP010302_00032 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP010302_00032 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP010302_00033 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP010302_00033 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP010302_00033 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP010302_00033 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP010302_00034 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP010302_00034 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP010302_00034 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP010302_00035 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP010302_00036 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP010302_00036 - 0.077 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP010302_00036 - 0.74 9.8 5.2 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP010302_00038 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP010302_00039 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP010302_00039 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP010302_00039 - 1.7e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP010302_00039 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP010302_00039 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP010302_00039 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pCP010302_00039 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP010302_00039 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pCP010302_00039 - 0.088 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 pCP010302_00039 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP010302_00039 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP010302_00039 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP010302_00039 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP010302_00039 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP010302_00039 - 6.9 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP010302_00039 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP010302_00040 - 2.7e-05 24.1 2.2 7.5e-05 22.6 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP010302_00040 - 0.016 15.2 4.6 0.14 12.1 4.6 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP010302_00042 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP010302_00042 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP010302_00042 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP010302_00042 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP010302_00042 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP010302_00042 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP010302_00042 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP010302_00042 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP010302_00042 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 pCP010302_00043 - 1.5e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP010302_00043 - 3.5e-06 27.0 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pCP010302_00043 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pCP010302_00043 - 0.088 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication APH PF01636.23 pCP010302_00044 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP010302_00044 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP010302_00044 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP010302_00044 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP010302_00044 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP010302_00044 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP010302_00045 - 1.6e-24 87.2 0.0 2.1e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Lip_prot_lig_C PF10437.9 pCP010302_00046 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP010302_00046 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP010302_00047 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pCP010302_00048 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP010302_00048 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP010302_00048 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP010302_00048 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP010302_00048 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP010302_00048 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP010302_00048 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pCP010302_00049 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP010302_00049 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP010302_00049 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP010302_00049 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP010302_00049 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP010302_00050 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP010302_00050 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP010302_00051 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP010302_00051 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP010302_00051 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP010302_00051 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP010302_00051 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP010302_00052 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP010302_00053 - 2e-16 59.6 0.8 6e-16 58.1 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP010302_00053 - 5.5e-08 33.0 8.4 5.5e-08 33.0 8.4 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP010302_00053 - 9.1e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP010302_00053 - 1.1e-05 25.3 1.8 0.0012 18.7 0.3 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP010302_00053 - 3.8e-05 24.1 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase HTH_3 PF01381.22 pCP010302_00054 - 4.7e-06 26.6 0.0 0.00046 20.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 pCP010302_00054 - 1.1e-05 25.3 0.2 0.011 15.7 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain Phage_CI_repr PF07022.13 pCP010302_00054 - 0.00047 20.2 0.0 0.081 13.0 0.0 2.5 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_23 PF13384.6 pCP010302_00054 - 0.0075 16.0 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 pCP010302_00054 - 0.0076 15.8 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pCP010302_00054 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP010302_00054 - 0.022 14.6 0.1 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_26 PF13443.6 pCP010302_00054 - 0.045 14.2 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 pCP010302_00054 - 0.1 12.8 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 pCP010302_00054 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_AlpA PF05930.12 pCP010302_00054 - 0.15 11.9 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Sigma70_r4_2 PF08281.12 pCP010302_00054 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 PcfJ PF14284.6 pCP011017_00002 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP011017_00002 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pCP011017_00003 - 1.7e-97 327.1 8.2 2.3e-97 326.6 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP011017_00003 - 4.7e-12 46.0 2.7 6.4e-12 45.6 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP011017_00003 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP011017_00003 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP011017_00003 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP011017_00003 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP011017_00003 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP011017_00003 - 0.055 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP011017_00003 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP011017_00003 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP011017_00003 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP011017_00003 - 0.42 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP011017_00003 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP011017_00003 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP011017_00003 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP011017_00003 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP011017_00003 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pCP011017_00004 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP011017_00006 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP011017_00006 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP011017_00006 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCP011017_00007 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP011017_00008 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP011017_00008 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP011017_00008 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP011017_00008 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCP011017_00009 - 7e-106 354.8 0.1 9.7e-106 354.3 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP011017_00009 - 9.6e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP011017_00009 - 7.2e-16 58.1 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 pCP011017_00010 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP011017_00010 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP011017_00010 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP011017_00010 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP011017_00010 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP011017_00010 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pCP011017_00010 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pCP011017_00010 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP011017_00010 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP011017_00010 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP011017_00010 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP011017_00010 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pCP011017_00010 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pCP011017_00010 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pCP011017_00010 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pCP011017_00010 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pCP011017_00010 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pCP011017_00010 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pCP011017_00010 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pCP011017_00010 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP011017_00010 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 pCP011017_00010 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 pCP011017_00010 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP011017_00010 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP011017_00010 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP011017_00010 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP011017_00010 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP011017_00010 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pCP011017_00010 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 pCP011017_00010 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP011017_00010 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP011017_00010 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP011017_00011 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP011017_00011 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP011017_00012 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pCP011017_00012 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 pCP011017_00012 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain VirB8 PF04335.13 pCP011017_00013 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP011017_00013 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP011017_00014 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pCP011017_00014 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pCP011017_00014 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP011017_00015 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP011017_00015 - 0.065 13.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pCP011017_00015 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) T4SS PF07996.11 pCP011017_00016 - 1e-28 101.1 13.2 1.5e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP011017_00016 - 0.0033 17.5 0.6 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pCP011017_00016 - 0.013 16.1 0.8 0.036 14.7 0.2 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Tissue_fac PF01108.17 pCP011017_00016 - 0.043 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Tissue factor AATF-Che1 PF13339.6 pCP011017_00016 - 0.45 11.2 11.4 0.41 11.3 4.5 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 pCP011017_00017 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP011017_00017 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP011017_00017 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP011017_00017 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP011017_00018 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 pCP011017_00019 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 pCP011017_00020 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pCP011017_00020 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pCP011017_00020 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 pCP011017_00021 - 2.4e-51 174.8 0.3 5.5e-51 173.6 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP011017_00021 - 6.9e-21 74.3 0.9 1.2e-20 73.5 0.9 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP011017_00021 - 0.046 13.2 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated TrbC PF04956.13 pCP011017_00022 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP011017_00022 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP011017_00024 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.8 1 1 1 2 2 2 2 CRISPR associated protein Cas2 Resolvase PF00239.21 pCP011017_00025 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP011017_00025 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP011017_00025 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP011017_00025 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pCP011017_00026 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP011017_00026 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP011017_00026 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP011017_00026 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP011017_00026 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP011017_00026 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP011017_00026 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 pCP011017_00027 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP011017_00028 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCP011017_00030 - 0.0016 18.5 0.4 0.0018 18.3 0.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4223 PF13978.6 pCP011017_00031 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pCP011017_00031 - 0.1 12.1 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 pCP011017_00032 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP011017_00032 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP011017_00032 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP011017_00032 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold ZYG-11_interact PF05884.12 pCP011017_00034 - 0.22 10.9 0.4 0.26 10.7 0.4 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 HTH_46 PF15977.5 pCP011017_00035 - 0.00021 21.2 5.7 0.12 12.4 0.6 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP011017_00035 - 0.046 13.8 1.9 0.067 13.3 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DndE PF08870.11 pCP011017_00035 - 0.29 11.4 5.6 0.5 10.7 0.8 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP011017_00035 - 0.3 11.4 6.2 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pCP011017_00035 - 0.32 11.1 8.7 1 9.4 0.3 3.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Relaxase PF03432.14 pCP011017_00036 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain Acetyltransf_7 PF13508.7 pCP011017_00037 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP011017_00037 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pCP011017_00037 - 0.0083 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NYN PF01936.18 pCP011017_00038 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pCP011017_00038 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pCP011017_00038 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) SNF2_N PF00176.23 pCP011017_00039 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP011017_00039 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP011017_00039 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP011017_00039 - 9.2e-06 25.5 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP011017_00039 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP011017_00040 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pCP011017_00040 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 pCP011017_00041 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP011017_00041 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP011017_00041 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP011017_00041 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP011017_00041 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP011017_00042 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP011017_00042 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP011017_00043 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP011017_00043 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP011017_00043 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP011017_00043 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP011017_00043 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP011017_00044 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP011017_00044 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP011017_00044 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP011017_00044 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP011017_00044 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP011017_00044 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP011017_00044 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pCP011017_00045 - 0.0057 16.0 1.4 0.0057 16.0 1.4 2.0 3 0 0 3 3 3 1 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 pCP011017_00045 - 1.9 7.5 5.4 2.3 7.2 5.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus CtsR_C PF17727.1 pCP011017_00046 - 0.041 14.0 0.3 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pCP011017_00047 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP011017_00047 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain DUF5442 PF17514.2 pCP011017_00049 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) EFG_C PF00679.24 pCP011017_00050 - 1.3e-17 63.6 0.0 1.8e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 pCP011017_00050 - 4.1e-08 33.0 0.0 5.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 pCP013033_00002 - 2.5e-59 200.1 0.3 3.4e-59 199.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP013033_00002 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP013033_00002 - 9.3e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP013033_00002 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP013033_00002 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP013033_00002 - 0.00029 21.2 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP013033_00002 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP013033_00002 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP013033_00002 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pCP013033_00002 - 0.15 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B LysE PF01810.18 pCP013033_00003 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP013033_00003 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP013033_00003 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP013033_00003 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP013033_00003 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP013033_00003 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP013033_00003 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP013033_00003 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP013033_00003 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP013033_00004 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP013033_00004 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP013033_00004 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP013033_00004 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP013033_00004 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP013033_00005 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP013033_00005 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP013033_00006 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP013033_00006 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP013033_00006 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP013033_00006 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP013033_00006 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP013033_00007 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP013033_00008 - 2e-16 59.7 0.9 5.7e-16 58.2 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP013033_00008 - 6.5e-08 32.8 8.6 6.5e-08 32.8 8.6 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP013033_00008 - 2.5e-06 27.8 1.7 4.8e-05 23.7 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP013033_00008 - 1.1e-05 25.2 2.0 0.0011 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP013033_00008 - 2.7e-05 24.6 0.7 0.00022 21.7 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase HTH_19 PF12844.7 pCP013033_00009 - 5.9e-05 23.0 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 pCP013033_00009 - 0.0013 18.8 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCP013033_00009 - 0.0024 17.9 0.0 0.18 11.9 0.1 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCP013033_00009 - 0.0046 16.5 0.0 0.062 12.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Imm3 PF14425.6 pCP013033_00009 - 0.028 14.5 0.2 0.057 13.5 0.2 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 YdaS_antitoxin PF15943.5 pCP013033_00009 - 0.028 14.3 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_AsnC-type PF13404.6 pCP013033_00009 - 0.041 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Crp PF00325.20 pCP013033_00009 - 0.053 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_28 PF13518.6 pCP013033_00009 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 pCP013033_00009 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Mga PF08280.11 pCP013033_00009 - 0.097 12.7 2.9 1.8 8.7 0.2 3.0 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 pCP013033_00009 - 0.21 11.0 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Relaxase PF03432.14 pCP013033_00010 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP013033_00011 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP013033_00011 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP013033_00011 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP013033_00011 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP013033_00011 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Sds3 PF08598.11 pCP013033_00012 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP013033_00012 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP013033_00012 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pCP013033_00014 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP013033_00015 - 3.6e-08 33.7 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP013033_00015 - 0.083 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain 5_3_exonuc PF01367.20 pCP013033_00015 - 0.083 13.5 4.7 0.46 11.1 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Toprim_4 PF13662.6 pCP013033_00015 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain DUF4223 PF13978.6 pCP013033_00016 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP013033_00016 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 pCP013033_00017 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 pCP013033_00018 - 2.6e-30 105.7 7.7 4.2e-30 105.0 7.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pCP013033_00018 - 1.6e-26 93.2 0.7 2.2e-26 92.7 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pCP013033_00018 - 4.7e-06 25.6 0.7 7e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 pCP013033_00018 - 0.0036 17.4 0.7 0.012 15.7 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ORC6 PF05460.13 pCP013033_00018 - 0.011 15.0 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HicB_lk_antitox PF15919.5 pCP013033_00020 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP013033_00020 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 pCP013033_00021 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP013033_00021 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP013033_00021 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP013033_00021 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP013033_00021 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP013033_00021 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pCP013033_00022 - 0.088 12.6 4.3 0.038 13.8 2.0 1.5 1 1 1 2 2 2 0 Group B Rotavirus Non-structural protein 5 FeoB_associated PF12669.7 pCP013033_00022 - 0.4 11.1 1.6 1.5 9.3 0.3 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Resolvase PF00239.21 pCP013033_00024 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP013033_00024 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP013033_00024 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP013033_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP013033_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP013033_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP013033_00027 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP013033_00027 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP013033_00028 - 2.1e-51 174.9 0.9 5.2e-51 173.7 0.9 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP013033_00028 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP013033_00028 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP013033_00028 - 0.038 14.1 5.4 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pCP013033_00029 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP013033_00029 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP013033_00029 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP013033_00029 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP013033_00029 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 pCP013033_00030 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 pCP013033_00031 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP013033_00032 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP013033_00032 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP013033_00032 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP013033_00032 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP013033_00033 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP013033_00033 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP013033_00033 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP013033_00033 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP013033_00033 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 pCP013033_00033 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 pCP013033_00033 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pCP013033_00033 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pCP013033_00034 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP013033_00034 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP013033_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP013033_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP013033_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP013033_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP013033_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP013033_00037 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP013033_00037 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP013033_00038 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP013033_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP013033_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP013033_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP013033_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP013033_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP013033_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP013033_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP013033_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP013033_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP013033_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP013033_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP013033_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP013033_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP013033_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP013033_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP013033_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP013033_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP013033_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP013033_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP013033_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP013033_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP013033_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP013033_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP013033_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP013033_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP013033_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP013033_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP013033_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP013033_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP013033_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP013033_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP013033_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP013033_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP013033_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP013033_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP013033_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP013033_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP013033_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP013033_00041 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP013033_00041 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP013033_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP013033_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP013033_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP013033_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP013033_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP013033_00046 - 1.7e-97 327.1 8.2 2.3e-97 326.6 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP013033_00046 - 4.3e-12 46.1 2.6 6.4e-12 45.6 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP013033_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP013033_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP013033_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP013033_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP013033_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP013033_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP013033_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP013033_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP013033_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP013033_00046 - 0.43 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP013033_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP013033_00046 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP013033_00046 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP013033_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP013033_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TrbC PF04956.13 pCP013035_00002 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP013035_00002 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP013035_00004 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP013035_00004 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pCP013035_00005 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP013035_00005 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP013035_00005 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP013035_00005 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pCP013035_00006 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP013035_00006 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP013035_00006 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP013035_00006 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP013035_00006 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP013035_00006 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP013035_00006 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 pCP013035_00007 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCP013035_00009 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pCP013035_00009 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pCP013035_00009 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 pCP013035_00010 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pCP013035_00010 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pCP013035_00010 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pCP013035_00010 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 pCP013035_00011 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP013035_00011 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pCP013035_00012 - 2.3e-08 34.3 0.0 4.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP013035_00012 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP013035_00012 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP013035_00012 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pCP013035_00013 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 pCP013035_00015 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP013035_00015 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP013035_00015 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCP013035_00016 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP013035_00016 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP013035_00016 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP013035_00016 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP013035_00016 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pCP013035_00017 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain Acetyltransf_7 PF13508.7 pCP013035_00018 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP013035_00018 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family SNF2_N PF00176.23 pCP013035_00019 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP013035_00019 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP013035_00019 - 9.8e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP013035_00019 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP013035_00019 - 2.9e-05 24.5 0.6 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP013035_00020 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCP013035_00021 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP013035_00021 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP013035_00021 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP013035_00021 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP013035_00021 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP013035_00022 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP013035_00022 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP013035_00023 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP013035_00023 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP013035_00023 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP013035_00023 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP013035_00023 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP013035_00024 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP013035_00024 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP013035_00024 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP013035_00024 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP013035_00024 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP013035_00024 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP013035_00024 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pCP013035_00025 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 pCP013035_00026 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP013035_00026 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pCP013035_00027 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon APH PF01636.23 pCP013035_00028 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP013035_00028 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP013035_00028 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family GTP_EFTU PF00009.27 pCP013035_00029 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP013035_00029 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP013035_00029 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP013035_00029 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP013035_00029 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP013035_00029 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP013035_00029 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP013035_00029 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP013035_00029 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pCP013035_00031 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP013035_00031 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 pCP013035_00032 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP013035_00032 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 pCP013035_00032 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 pCP013035_00032 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 pCP013035_00032 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP013035_00032 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain Redoxin PF08534.10 pCP013035_00033 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP013035_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP013035_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP013035_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCP013035_00036 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP013035_00037 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP013035_00037 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP013035_00037 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP013035_00037 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCP013035_00038 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP013035_00038 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP013035_00038 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP013035_00038 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pCP013035_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP013035_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP013035_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP013035_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP013035_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP013035_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP013035_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP013035_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP013035_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP013035_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP013035_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP013035_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP013035_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP013035_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP013035_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP013035_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP013035_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP013035_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP013035_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP013035_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP013035_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP013035_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP013035_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP013035_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP013035_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP013035_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP013035_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP013035_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP013035_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP013035_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP013035_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP013035_00040 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP013035_00040 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP013035_00041 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP013035_00041 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCP013035_00042 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP013035_00042 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP013035_00043 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP013035_00043 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP013035_00044 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP013035_00044 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP013035_00044 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pCP013035_00045 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP013035_00045 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP013035_00045 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP013035_00045 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP013035_00045 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCP013035_00045 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pCP013035_00045 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pCP013035_00045 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pCP013035_00046 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP013035_00046 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP013035_00046 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP013035_00046 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP013035_00047 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 pCP013035_00048 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP013035_00048 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP013035_00048 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP013035_00048 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP013035_00048 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP013035_00048 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 pCP013035_00049 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP013035_00049 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP013035_00049 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP013035_00049 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP013035_00049 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pCP013035_00050 - 2e-06 28.0 0.4 5.3e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 CagE, TrbE, VirB family, component of type IV transporter system AAA_10 PF12846.7 pCP013035_00050 - 7.4e-06 25.1 1.2 2e-05 23.7 1.2 1.6 1 1 0 1 1 1 1 AAA-like domain HNOBA PF07701.14 pCP013035_00050 - 0.017 14.6 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 pCP013035_00050 - 0.2 11.6 0.0 0.47 10.4 0.0 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like CagX PF03524.15 pCP013037_00002 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP013037_00002 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCP013037_00003 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP013037_00003 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP013037_00004 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP013037_00004 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP013037_00005 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP013037_00005 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP013037_00005 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pCP013037_00006 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP013037_00006 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP013037_00006 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP013037_00006 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP013037_00006 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 pCP013037_00006 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 pCP013037_00006 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pCP013037_00006 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pCP013037_00007 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP013037_00007 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP013037_00007 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP013037_00007 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP013037_00008 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 pCP013037_00009 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 pCP013037_00010 - 6.4e-29 100.4 0.0 1.1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP013037_00010 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP013037_00010 - 0.011 15.3 0.4 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP013037_00010 - 0.061 13.3 0.1 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP013037_00010 - 1.1 9.4 7.5 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pCP013037_00011 - 2.1e-51 174.9 0.9 5.2e-51 173.7 0.9 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP013037_00011 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP013037_00011 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP013037_00011 - 0.038 14.1 5.4 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 pCP013037_00012 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP013037_00012 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP013037_00014 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP013037_00014 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pCP013037_00015 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP013037_00015 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP013037_00015 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP013037_00015 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat GBR_NSP5 PF17580.2 pCP013037_00017 - 0.088 12.6 4.3 0.038 13.8 2.0 1.5 1 1 1 2 2 2 0 Group B Rotavirus Non-structural protein 5 FeoB_associated PF12669.7 pCP013037_00017 - 0.4 11.1 1.6 1.5 9.3 0.3 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein AAA_25 PF13481.6 pCP013037_00018 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP013037_00018 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP013037_00018 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP013037_00018 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP013037_00018 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP013037_00018 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicB_lk_antitox PF15919.5 pCP013037_00019 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP013037_00019 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain Pkinase PF00069.25 pCP013037_00021 - 2.6e-30 105.7 7.7 4.2e-30 105.0 7.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pCP013037_00021 - 1.6e-26 93.2 0.7 2.2e-26 92.7 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pCP013037_00021 - 4.7e-06 25.6 0.7 7e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 pCP013037_00021 - 0.0036 17.4 0.7 0.012 15.7 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ORC6 PF05460.13 pCP013037_00021 - 0.011 15.0 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TOPRIM_C PF16898.5 pCP013037_00022 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM DUF4223 PF13978.6 pCP013037_00023 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP013037_00023 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pCP013037_00024 - 3.6e-08 33.7 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP013037_00024 - 0.083 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain 5_3_exonuc PF01367.20 pCP013037_00024 - 0.083 13.5 4.7 0.46 11.1 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Toprim_4 PF13662.6 pCP013037_00024 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain DUF2400 PF09674.10 pCP013037_00025 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 pCP013037_00027 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP013037_00027 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP013037_00027 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCP013037_00028 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP013037_00028 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP013037_00028 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP013037_00028 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP013037_00028 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 pCP013037_00029 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 pCP013037_00030 - 5.9e-05 23.0 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 pCP013037_00030 - 0.0013 18.8 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCP013037_00030 - 0.0024 17.9 0.0 0.18 11.9 0.1 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCP013037_00030 - 0.0046 16.5 0.0 0.062 12.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Imm3 PF14425.6 pCP013037_00030 - 0.028 14.5 0.2 0.057 13.5 0.2 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 YdaS_antitoxin PF15943.5 pCP013037_00030 - 0.028 14.3 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_AsnC-type PF13404.6 pCP013037_00030 - 0.041 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Crp PF00325.20 pCP013037_00030 - 0.053 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_28 PF13518.6 pCP013037_00030 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 pCP013037_00030 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Mga PF08280.11 pCP013037_00030 - 0.097 12.7 2.9 1.8 8.7 0.2 3.0 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 pCP013037_00030 - 0.21 11.0 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 SNF2_N PF00176.23 pCP013037_00031 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP013037_00031 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP013037_00031 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP013037_00031 - 1.3e-05 25.1 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP013037_00031 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP013037_00032 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCP013037_00033 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP013037_00033 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP013037_00033 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP013037_00033 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP013037_00033 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP013037_00034 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP013037_00034 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP013037_00035 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP013037_00035 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP013037_00035 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP013037_00035 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP013037_00035 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP013037_00036 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP013037_00036 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP013037_00036 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP013037_00036 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP013037_00036 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP013037_00036 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP013037_00036 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP013037_00036 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP013037_00036 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase GTP_EFTU PF00009.27 pCP013037_00037 - 8.1e-59 198.4 0.4 1.1e-58 198.0 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP013037_00037 - 1.3e-22 79.9 0.0 3.5e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP013037_00037 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP013037_00037 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP013037_00037 - 1.8e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP013037_00037 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP013037_00037 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP013037_00037 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP013037_00037 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pCP013037_00039 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP013037_00039 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pCP013037_00040 - 1.2e-97 327.5 8.2 1.6e-97 327.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP013037_00040 - 3.6e-12 46.4 2.9 5.3e-12 45.9 0.1 2.8 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP013037_00040 - 0.011 15.5 1.7 0.028 14.2 1.7 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 pCP013037_00040 - 0.077 12.9 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zinc_ribbon_9 PF14369.6 pCP013037_00040 - 0.22 11.8 0.7 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon HTH_34 PF13601.6 pCP013037_00040 - 0.22 11.7 2.8 0.74 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain Redoxin PF08534.10 pCP013037_00041 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP013037_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP013037_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP013037_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCP013037_00044 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP013037_00045 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP013037_00045 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP013037_00045 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP013037_00045 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCP013037_00046 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP013037_00046 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP013037_00046 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP013037_00046 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pCP013037_00047 - 4.6e-54 183.3 0.0 5.3e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP013037_00047 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP013037_00047 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP013037_00047 - 0.00022 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP013037_00047 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP013037_00047 - 0.0027 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP013037_00047 - 0.0031 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP013037_00047 - 0.0037 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP013037_00047 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP013037_00047 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP013037_00047 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP013037_00047 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP013037_00047 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP013037_00047 - 0.021 14.8 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP013037_00047 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP013037_00047 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP013037_00047 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP013037_00047 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP013037_00047 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 pCP013037_00047 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pCP013037_00047 - 0.038 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.12 pCP013037_00047 - 0.04 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP013037_00047 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP013037_00047 - 0.062 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP013037_00047 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP013037_00047 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP013037_00047 - 0.092 12.7 0.4 0.24 11.3 0.2 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP013037_00047 - 0.12 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP013037_00047 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 pCP013037_00047 - 0.15 12.6 0.1 0.38 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 pCP013037_00047 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP013037_00047 - 0.22 12.0 2.5 0.32 11.5 1.3 1.7 1 1 0 1 1 1 0 AAA domain TrbI PF03743.14 pCP013037_00048 - 1.1e-10 41.6 0.1 1.3e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP013037_00048 - 0.0018 17.4 0.1 0.002 17.3 0.1 1.1 1 0 0 1 1 1 1 HaeIII restriction endonuclease Adenyl_transf PF04439.12 pCP013117_00001 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pCP013117_00002 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pCP013117_00002 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pCP013117_00002 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pCP013117_00002 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pCP013117_00002 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pCP013117_00002 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pCP013117_00002 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pCP013117_00002 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pCP013117_00003 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP013117_00003 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP013117_00003 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 pCP013117_00004 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pCP013117_00005 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP013117_00005 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 pCP013117_00006 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP013117_00006 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP013117_00006 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP013117_00006 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP013117_00006 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP013117_00006 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP013117_00006 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP013117_00006 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP013117_00006 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP013117_00007 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP013117_00007 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP013117_00007 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP013117_00007 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP013117_00007 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP013117_00008 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP013117_00008 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP013117_00009 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP013117_00009 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP013117_00009 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP013117_00009 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP013117_00009 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP013117_00010 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP013117_00011 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP013117_00011 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP013117_00011 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP013117_00011 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP013117_00011 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pCP013117_00012 - 0.0008 19.8 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP013117_00012 - 0.032 14.5 0.1 0.066 13.4 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Peptidase_S24 PF00717.23 pCP013117_00013 - 3.3e-12 46.2 0.0 6.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Phage_CI_repr PF07022.13 pCP013117_00013 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4_2 PF08281.12 pCP013117_00013 - 0.048 13.3 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_10 PF04967.12 pCP013117_00013 - 0.056 13.3 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain Fe_dep_repress PF01325.19 pCP013117_00013 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 pCP013117_00013 - 0.18 11.6 0.0 0.73 9.7 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain RepB-RCR_reg PF10723.9 pCP013117_00014 - 0.057 13.4 1.2 0.13 12.3 1.2 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB PdaC PF13739.6 pCP013117_00014 - 2.4 9.2 5.8 9.8 7.2 5.8 2.0 1 1 0 1 1 1 0 Deacetylase PdaC CdhC PF03598.15 pCP013117_00015 - 0.052 13.4 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit SinI PF08671.10 pCP013117_00015 - 0.076 12.8 0.1 0.076 12.8 0.1 2.2 3 0 0 3 3 3 0 Anti-repressor SinI Ank_2 PF12796.7 pCP013117_00016 - 2.1e-05 25.0 0.1 3.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pCP013117_00016 - 0.011 16.2 0.1 0.18 12.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat DUF3447 PF11929.8 pCP013117_00016 - 0.012 15.6 3.0 0.013 15.5 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) MethyltransfD12 PF02086.15 pCP013117_00017 - 1.5e-28 100.2 6.6 3e-28 99.2 6.6 1.4 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Phage_GPD PF05954.11 pCP013117_00018 - 3.2e-06 26.7 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) PTH2 PF01981.16 pCP013117_00018 - 0.031 14.6 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Phage_tail_X PF05489.12 pCP013117_00019 - 2.5e-10 39.9 0.0 3.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Phage Tail Protein X Phage_P2_GpU PF06995.11 pCP013117_00020 - 1.2e-18 66.9 0.0 1.5e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Phage P2 GpU PhageMin_Tail PF10145.9 pCP013117_00021 - 1.5e-22 80.4 18.9 1.5e-22 80.4 18.9 3.8 2 1 2 4 4 4 2 Phage-related minor tail protein DUF3450 PF11932.8 pCP013117_00021 - 4.6e-06 26.1 0.6 0.15 11.3 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3450) DLP_helical PF18709.1 pCP013117_00021 - 0.017 14.3 0.4 0.017 14.3 0.4 3.2 2 1 1 3 3 3 0 Dynamin-like helical domain Dor1 PF04124.12 pCP013117_00021 - 0.037 12.7 1.4 0.063 12.0 0.6 1.8 2 0 0 2 2 2 0 Dor1-like family HD_2 PF12917.7 pCP013117_00021 - 0.06 13.1 2.9 0.076 12.8 0.1 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme HAUS-augmin3 PF14932.6 pCP013117_00021 - 0.064 12.8 8.5 0.53 9.8 2.4 3.4 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF16 PF01519.16 pCP013117_00021 - 0.086 13.3 3.1 1.1 9.8 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF3847 PF12958.7 pCP013117_00021 - 0.11 12.6 4.4 1.4 9.1 0.0 3.8 4 1 1 5 5 4 0 Protein of unknown function (DUF3847) APC1_C PF18122.1 pCP013117_00021 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain BLOC1_2 PF10046.9 pCP013117_00021 - 0.15 12.4 15.0 0.15 12.4 0.3 5.8 7 0 0 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 pCP013117_00021 - 0.61 10.1 19.4 0.75 9.8 1.3 4.7 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 pCP013117_00021 - 0.87 9.8 4.6 11 6.2 1.0 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 pCP013117_00021 - 1.2 7.9 6.5 6.7 5.5 1.3 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4795 PF16043.5 pCP013117_00021 - 1.3 8.5 10.7 0.49 10.0 1.7 3.5 2 2 0 3 3 3 0 Domain of unknown function (DUF4795) Sigma70_ner PF04546.13 pCP013117_00021 - 2.2 8.1 7.5 29 4.5 1.8 3.5 4 0 0 4 4 4 0 Sigma-70, non-essential region APG6_N PF17675.1 pCP013117_00021 - 4.9 7.7 5.9 38 4.8 0.5 3.1 3 1 0 3 3 3 0 Apg6 coiled-coil region MgtE PF01769.16 pCP013117_00022 - 0.065 13.6 4.9 0.072 13.5 4.9 1.0 1 0 0 1 1 1 0 Divalent cation transporter DUF4234 PF14018.6 pCP013117_00022 - 0.5 10.5 6.7 1.1 9.4 6.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) DUF2207 PF09972.9 pCP013117_00022 - 5.5 5.6 8.9 6 5.5 8.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_TAC_7 PF10109.9 pCP013117_00023 - 5.2e-05 23.3 0.0 6.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 Phage_tube PF04985.14 pCP013117_00024 - 1e-29 103.4 0.0 1.1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein FII Phage_sheath_1C PF17482.2 pCP013117_00025 - 0.0025 17.7 0.3 0.031 14.3 0.2 2.6 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain DUF1353 PF07087.11 pCP013117_00027 - 5.8e-19 67.6 0.0 6.9e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) DUF4376 PF14301.6 pCP013117_00028 - 1.3e-10 41.6 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4376) CENP-X PF09415.10 pCP013117_00028 - 0.022 15.0 0.1 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF3751 PF12571.8 pCP013117_00029 - 8e-38 129.9 0.0 1.7e-37 128.8 0.0 1.6 1 0 0 1 1 1 1 Phage tail-collar fibre protein BppL_N PF18338.1 pCP013117_00029 - 0.0018 18.0 0.4 0.0042 16.8 0.4 1.6 1 0 0 1 1 1 1 Lower baseplate protein N-terminal domain Peptidase_M28 PF04389.17 pCP013117_00029 - 0.062 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Tail_P2_I PF09684.10 pCP013117_00030 - 2.5e-23 82.5 0.0 3.6e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) Acp26Ab PF05777.12 pCP013117_00030 - 0.08 13.6 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) SIN1_PH PF16979.5 pCP013117_00030 - 0.11 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Baseplate_J PF04865.14 pCP013117_00031 - 5.1e-24 84.8 0.0 9.1e-24 84.0 0.0 1.4 1 1 0 1 1 1 1 Baseplate J-like protein GPW_gp25 PF04965.14 pCP013117_00032 - 1.3e-13 50.6 0.0 1.5e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Gene 25-like lysozyme Phage_base_V PF04717.12 pCP013117_00033 - 1.1e-18 67.2 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector WTF PF03303.13 pCP013117_00033 - 0.14 11.9 0.5 0.19 11.4 0.5 1.1 1 0 0 1 1 1 0 WTF protein DUF1804 PF08822.11 pCP013117_00034 - 1e-09 38.6 0.2 1.2e-09 38.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_29 PF13551.6 pCP013117_00034 - 0.0057 16.6 0.0 0.079 13.0 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 pCP013117_00034 - 0.0077 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Mu-like_Pro PF10123.9 pCP013117_00035 - 1.7e-25 90.2 1.1 2.3e-25 89.8 1.1 1.2 1 0 0 1 1 1 1 Mu-like prophage I protein DUF812 PF05667.11 pCP013117_00035 - 0.00088 18.3 14.1 0.0012 17.8 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 pCP013117_00035 - 0.0032 16.4 15.8 0.0052 15.7 15.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein HALZ PF02183.18 pCP013117_00035 - 0.0036 17.5 3.9 0.0036 17.5 3.9 2.7 2 1 0 2 2 2 1 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 pCP013117_00035 - 0.0063 16.7 26.1 0.0063 16.7 26.1 1.8 1 1 0 1 1 1 1 Tropomyosin like Alpha-2-MRAP_C PF06401.11 pCP013117_00035 - 0.026 14.5 13.1 0.014 15.4 10.4 1.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain HemX PF04375.14 pCP013117_00035 - 0.055 12.7 10.2 0.17 11.2 10.7 1.5 2 0 0 2 2 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FlaC_arch PF05377.11 pCP013117_00035 - 0.064 13.6 0.6 0.064 13.6 0.6 3.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 pCP013117_00035 - 0.098 12.7 16.6 0.18 11.9 16.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 pCP013117_00035 - 0.1 11.7 9.9 0.15 11.2 9.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 pCP013117_00035 - 0.11 12.1 8.3 0.19 11.3 8.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Golgin_A5 PF09787.9 pCP013117_00035 - 0.13 11.7 12.9 0.2 11.1 12.9 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 FlgN PF05130.12 pCP013117_00035 - 0.15 12.6 15.7 0.31 11.6 15.7 1.6 1 0 0 1 1 1 0 FlgN protein TPR_MLP1_2 PF07926.12 pCP013117_00035 - 0.15 12.2 25.0 1.9 8.5 25.0 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 pCP013117_00035 - 0.21 11.8 7.5 0.47 10.6 7.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PCRF PF03462.18 pCP013117_00035 - 0.33 10.8 11.2 0.75 9.6 11.2 1.6 1 0 0 1 1 1 0 PCRF domain DUF5320 PF17253.2 pCP013117_00035 - 0.35 12.0 6.6 7.3 7.7 0.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF3578 PF12102.8 pCP013117_00035 - 0.77 9.3 6.4 0.12 12.0 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3578) Uso1_p115_C PF04871.13 pCP013117_00035 - 0.81 10.1 23.3 0.49 10.8 20.6 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fzo_mitofusin PF04799.13 pCP013117_00035 - 1.2 8.6 4.4 1.4 8.4 3.4 1.6 1 1 0 1 1 1 0 fzo-like conserved region DUF2203 PF09969.9 pCP013117_00035 - 1.6 9.4 5.7 4.9 7.9 5.7 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Snapin_Pallidin PF14712.6 pCP013117_00035 - 1.8 9.0 12.1 0.1 13.0 3.2 2.7 2 0 0 2 2 2 0 Snapin/Pallidin T3SS_basalb_I PF17001.5 pCP013117_00035 - 2.9 8.6 9.2 1.1 9.9 2.9 2.6 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI ZapB PF06005.12 pCP013117_00035 - 3.2 8.3 27.1 0.9 10.0 11.6 3.0 2 0 0 2 2 2 0 Cell division protein ZapB Cwf_Cwc_15 PF04889.12 pCP013117_00035 - 3.4 7.3 16.3 4.7 6.9 16.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TMPIT PF07851.13 pCP013117_00035 - 4.4 6.5 8.7 6.8 5.8 8.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein MutS_IV PF05190.18 pCP013117_00035 - 4.6 7.7 13.0 4.7 7.6 2.2 3.6 3 0 0 3 3 3 0 MutS family domain IV LMBR1 PF04791.16 pCP013117_00035 - 5.4 5.8 6.0 6.4 5.6 6.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 pCP013117_00035 - 6 6.7 14.6 0.4 10.5 3.6 2.8 2 0 0 2 2 2 0 Septum formation initiator 5_nucleotid PF05761.14 pCP013117_00035 - 6.5 5.5 8.6 9.6 5.0 8.6 1.2 1 0 0 1 1 1 0 5' nucleotidase family Csm1_N PF18504.1 pCP013117_00035 - 6.6 7.2 20.7 0.42 11.0 4.3 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF2508 PF10704.9 pCP013117_00035 - 7.5 6.8 12.7 12 6.1 3.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) HalX PF08663.10 pCP013117_00035 - 9.3 6.7 17.5 2.7 8.4 2.4 2.5 1 1 1 2 2 2 0 HalX domain Mu-like_gpT PF10124.9 pCP013117_00036 - 3.4e-75 253.1 2.8 1e-37 130.0 0.2 3.0 1 1 2 3 3 3 3 Mu-like prophage major head subunit gpT SplA PF11132.8 pCP013117_00037 - 0.0073 16.1 0.7 0.37 10.6 0.2 2.2 1 1 1 2 2 2 2 Transcriptional regulator protein (SplA) tRNA-synt_1g PF09334.11 pCP013117_00037 - 0.065 12.0 4.2 0.073 11.8 4.2 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (M) DNAP_B_exo_N PF08452.10 pCP013117_00037 - 1.6 8.2 6.8 19 4.8 0.0 3.3 3 0 0 3 3 3 0 DNA polymerase family B exonuclease domain, N-terminal Peptidase_M15_3 PF08291.11 pCP013117_00040 - 1.4e-23 83.1 0.0 1.6e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase M15 Peptidase_M15_2 PF05951.13 pCP013117_00040 - 4e-06 26.6 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Extensin-like_C PF06904.12 pCP013117_00040 - 0.07 13.2 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Extensin-like protein C-terminus Phage_holin_3_3 PF16083.5 pCP013117_00044 - 3.3e-10 39.9 3.8 4e-10 39.7 3.8 1.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III Phage_holin_3_1 PF05106.12 pCP013117_00044 - 0.0016 18.8 1.7 0.0047 17.3 1.6 1.8 1 1 0 1 1 1 1 Phage holin family (Lysis protein S) DUF3397 PF11877.8 pCP013117_00044 - 0.053 13.7 3.4 0.076 13.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DUF3959 PF13105.6 pCP013117_00044 - 0.11 12.0 1.9 0.12 11.8 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) ResIII PF04851.15 pCP013117_00045 - 0.002 18.2 2.7 0.0029 17.6 0.5 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Terminase_6C PF17289.2 pCP013117_00045 - 0.064 13.4 0.0 1 9.5 0.0 2.3 1 1 0 1 1 1 0 Terminase RNaseH-like domain DUF935 PF06074.12 pCP013117_00046 - 2.8e-44 151.8 0.0 1.8e-43 149.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF935) DUF2119 PF09892.9 pCP013117_00046 - 0.072 12.5 0.6 0.17 11.3 0.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Phage_Mu_F PF04233.14 pCP013117_00047 - 1.6e-21 77.1 0.9 3.8e-21 75.9 0.9 1.7 1 0 0 1 1 1 1 Phage Mu protein F like protein PBECR2 PF18810.1 pCP013117_00047 - 5.8e-14 52.4 0.5 1.4e-13 51.2 0.5 1.6 1 0 0 1 1 1 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_tail_S PF05069.13 pCP013117_00048 - 1.6e-14 54.0 0.1 1.9e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Phage virion morphogenesis family BORCS7 PF16088.5 pCP013117_00048 - 0.014 15.6 1.3 0.03 14.6 1.0 1.6 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DUF2387 PF09526.10 pCP013117_00049 - 0.00073 19.6 0.3 0.00076 19.6 0.3 1.2 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.7 pCP013117_00049 - 0.0045 16.9 1.5 0.0063 16.5 1.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 pCP013117_00049 - 0.07 13.5 0.1 0.085 13.3 0.1 1.1 1 0 0 1 1 1 0 Restriction alleviation protein Lar eIF-5_eIF-2B PF01873.17 pCP013117_00049 - 0.11 12.4 2.0 0.15 11.9 2.0 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 TFIIS_C PF01096.18 pCP013117_00049 - 0.13 12.2 5.2 0.85 9.5 5.2 2.0 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) DUF1660 PF07874.11 pCP013117_00049 - 0.15 12.5 2.1 0.74 10.3 0.3 2.0 1 1 1 2 2 2 0 Prophage protein (DUF1660) zinc_ribbon_2 PF13240.6 pCP013117_00049 - 0.24 11.2 2.6 3.3 7.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 pCP013117_00049 - 0.55 10.2 0.2 0.55 10.2 0.2 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon UPF0547 PF10571.9 pCP013117_00049 - 1.1 9.4 4.2 7.6 6.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 YopX PF09643.10 pCP013117_00052 - 1.3e-18 67.3 5.8 2.7e-18 66.3 5.8 1.5 1 1 0 1 1 1 1 YopX protein MgtE_N PF03448.17 pCP013117_00053 - 5.1e-05 23.8 1.7 0.00075 20.1 1.6 2.0 1 1 0 1 1 1 1 MgtE intracellular N domain CRISPR_Cas9_WED PF18061.1 pCP013117_00053 - 0.064 13.3 0.2 0.087 12.9 0.2 1.3 1 1 0 1 1 1 0 CRISPR-Cas9 WED domain RNA_capsid PF03035.14 pCP013117_00054 - 0.034 14.2 0.3 0.034 14.2 0.3 1.0 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Phage_Mu_Gam PF07352.12 pCP013117_00055 - 1.2e-33 116.2 4.5 1.4e-33 116.0 4.5 1.0 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein NPM1-C PF16276.5 pCP013117_00055 - 0.054 13.5 0.1 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain YvrJ PF12841.7 pCP013117_00055 - 0.38 10.3 2.6 17 5.1 0.1 3.1 3 0 0 3 3 3 0 YvrJ protein family DUF4406 PF14359.6 pCP013117_00056 - 0.0002 21.8 0.0 0.00033 21.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4406) DUF1937 PF09152.10 pCP013117_00056 - 0.0077 17.0 0.0 0.016 16.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1937) PVL_ORF50 PF07768.11 pCP013117_00057 - 7.3e-05 23.1 0.5 0.0001 22.6 0.4 1.4 1 1 0 1 1 1 1 PVL ORF-50-like family Sigma70_r4 PF04545.16 pCP013117_00059 - 2.4e-08 33.4 0.1 3e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 pCP013117_00059 - 0.00011 21.8 0.1 0.00015 21.4 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 pCP013117_00059 - 0.0061 16.6 0.0 0.0095 16.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-70 region 3 HTH_Tnp_ISL3 PF13542.6 pCP013117_00059 - 0.0062 15.9 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 pCP013117_00059 - 0.014 14.9 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 pCP013117_00059 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GerE PF00196.19 pCP013117_00059 - 0.022 14.3 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family AAA_22 PF13401.6 pCP013117_00060 - 1.2e-19 71.0 0.1 2.9e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 pCP013117_00060 - 3e-09 36.6 0.8 1.6e-08 34.2 0.8 2.1 1 1 0 1 1 1 1 Bacterial TniB protein AAA_30 PF13604.6 pCP013117_00060 - 5.1e-09 36.1 0.0 9.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pCP013117_00060 - 1e-06 29.2 0.5 2.4e-05 24.8 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 pCP013117_00060 - 2.2e-05 24.0 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 pCP013117_00060 - 2.7e-05 24.7 0.4 0.019 15.5 0.1 2.5 1 1 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 pCP013117_00060 - 6.3e-05 23.3 0.4 0.00084 19.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 pCP013117_00060 - 0.00024 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 pCP013117_00060 - 0.0006 19.8 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 pCP013117_00060 - 0.00092 19.6 0.3 0.0023 18.4 0.1 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 pCP013117_00060 - 0.0011 18.8 0.1 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 pCP013117_00060 - 0.0014 18.6 3.0 0.016 15.1 0.1 2.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 pCP013117_00060 - 0.0015 17.9 0.1 0.0034 16.7 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Cys_Met_Meta_PP PF01053.20 pCP013117_00060 - 0.0016 17.0 0.0 0.0028 16.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sigma54_activat PF00158.26 pCP013117_00060 - 0.002 17.8 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.6 pCP013117_00060 - 0.0026 17.6 0.5 0.008 16.0 0.1 2.0 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 pCP013117_00060 - 0.0027 17.5 0.2 0.0092 15.7 0.1 1.9 2 1 0 2 2 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 pCP013117_00060 - 0.0037 17.3 0.1 0.008 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 pCP013117_00060 - 0.006 16.5 0.1 0.051 13.5 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase ATPase PF06745.13 pCP013117_00060 - 0.0096 15.3 0.1 0.019 14.3 0.1 1.6 1 1 0 1 1 1 1 KaiC T2SSE PF00437.20 pCP013117_00060 - 0.0099 15.0 0.1 0.017 14.2 0.1 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein TK PF00265.18 pCP013117_00060 - 0.016 15.1 0.1 0.04 13.8 0.0 1.8 2 0 0 2 2 1 0 Thymidine kinase Helicase_RecD PF05127.14 pCP013117_00060 - 0.019 14.8 0.7 0.12 12.2 0.2 2.1 1 1 1 2 2 2 0 Helicase PhoH PF02562.16 pCP013117_00060 - 0.021 14.2 0.2 0.057 12.9 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 pCP013117_00060 - 0.028 14.3 0.1 1.8 8.5 0.0 2.4 1 1 0 2 2 2 0 Rad17 P-loop domain HTH_19 PF12844.7 pCP013117_00060 - 0.04 14.0 1.0 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain PEPCK_ATP PF01293.20 pCP013117_00060 - 0.045 12.4 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_23 PF13476.6 pCP013117_00060 - 0.051 14.1 1.5 0.051 14.1 1.5 2.4 2 2 1 3 3 3 0 AAA domain AAA_29 PF13555.6 pCP013117_00060 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIE_beta PF02186.15 pCP013117_00060 - 0.085 13.1 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 TFIIE beta subunit core domain NB-ARC PF00931.22 pCP013117_00060 - 0.097 11.8 0.4 0.43 9.7 0.4 2.1 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 pCP013117_00060 - 0.11 13.0 0.2 0.4 11.1 0.0 2.2 2 1 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 pCP013117_00060 - 0.18 11.4 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain rve PF00665.26 pCP013117_00061 - 2.4e-11 43.8 0.0 5.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 pCP013117_00061 - 9.5e-05 22.3 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Mu transposase, C-terminal CSRNP_N PF16019.5 pCP013117_00061 - 0.33 10.8 4.2 2.1 8.2 0.9 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus HTH_3 PF01381.22 pCP013117_00064 - 3.6e-12 46.1 0.2 9.2e-12 44.8 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix Peptidase_S24 PF00717.23 pCP013117_00064 - 2.8e-11 43.2 0.0 9.2e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase S24-like HTH_19 PF12844.7 pCP013117_00064 - 6.9e-10 38.8 0.2 1.5e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 pCP013117_00064 - 1.4e-06 28.6 0.0 3.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 pCP013117_00064 - 3.6e-05 23.5 0.2 0.00011 22.0 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 pCP013117_00064 - 0.009 15.8 0.1 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_8 PF02954.19 pCP013117_00064 - 0.047 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 pCP013117_00064 - 0.055 13.1 0.3 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 YdaS_antitoxin PF15943.5 pCP013117_00064 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR PF00376.23 pCP013117_00064 - 0.14 12.0 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 MerR family regulatory protein HTH_24 PF13412.6 pCP013117_00064 - 0.15 11.7 0.9 0.66 9.6 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Relaxase PF03432.14 pCP013117_00065 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP013117_00066 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP013117_00066 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP013117_00066 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP013117_00066 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP013117_00066 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pCP013117_00067 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP013117_00067 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP013117_00067 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pCP013117_00070 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP013117_00070 - 0.016 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP013117_00070 - 0.017 15.2 6.4 1.2 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 DUF4223 PF13978.6 pCP013117_00071 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP013117_00071 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 pCP013117_00072 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 pCP013117_00073 - 5.1e-29 101.4 6.3 9.5e-29 100.6 6.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pCP013117_00073 - 2e-26 92.8 0.9 3.2e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pCP013117_00073 - 4e-06 25.9 0.8 5.9e-06 25.3 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 pCP013117_00073 - 0.0032 17.5 0.9 0.0087 16.1 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) RIO1 PF01163.22 pCP013117_00073 - 0.0073 15.9 2.5 0.0073 15.9 2.5 1.6 2 0 0 2 2 2 1 RIO1 family ORC6 PF05460.13 pCP013117_00073 - 0.0086 15.4 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pectate_lyase_3 PF12708.7 pCP013117_00073 - 0.068 13.0 0.4 0.14 12.0 0.4 1.4 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pex19 PF04614.12 pCP013117_00073 - 3.6 7.3 5.4 7.5 6.2 5.4 1.5 1 0 0 1 1 1 0 Pex19 protein family HicB_lk_antitox PF15919.5 pCP013117_00075 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP013117_00075 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 pCP013117_00076 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP013117_00076 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP013117_00076 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP013117_00076 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP013117_00076 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP013117_00076 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pCP013117_00077 - 0.013 15.3 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pCP013117_00079 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP013117_00079 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP013117_00079 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP013117_00079 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP013117_00080 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP013117_00080 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP013117_00082 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP013117_00082 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP013117_00083 - 1.3e-51 175.6 0.7 3e-51 174.5 0.7 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP013117_00083 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP013117_00083 - 0.046 13.2 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP013117_00084 - 1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP013117_00084 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 pCP013117_00085 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP013117_00085 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP013117_00085 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP013117_00085 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP013117_00085 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP013117_00085 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP013117_00086 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP013117_00087 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP013117_00087 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP013117_00087 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP013117_00087 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP013117_00088 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP013117_00088 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP013117_00088 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP013117_00088 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pCP013117_00088 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pCP013117_00088 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 pCP013117_00089 - 4.7e-29 101.7 31.2 4.7e-29 101.7 31.2 1.8 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP013117_00089 - 0.22 11.3 1.3 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP013117_00089 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP013117_00090 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP013117_00090 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP013117_00091 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP013117_00091 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP013117_00092 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP013117_00092 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP013117_00093 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP013117_00093 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP013117_00094 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP013117_00094 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP013117_00094 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP013117_00094 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP013117_00094 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP013117_00094 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP013117_00094 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP013117_00094 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP013117_00094 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP013117_00094 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP013117_00094 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP013117_00094 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP013117_00094 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP013117_00094 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP013117_00094 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP013117_00094 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP013117_00094 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP013117_00094 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP013117_00094 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP013117_00094 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP013117_00094 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP013117_00094 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP013117_00094 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP013117_00094 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP013117_00094 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP013117_00094 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP013117_00094 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP013117_00094 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP013117_00094 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP013117_00094 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP013117_00094 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP013117_00095 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP013117_00095 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP013117_00095 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP013117_00095 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP013117_00096 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP013117_00096 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP013117_00096 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP013117_00096 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP013117_00097 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP013117_00098 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP013117_00098 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP013117_00098 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP013117_00100 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP013117_00101 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP013117_00101 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 pCP013117_00101 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 pCP013117_00101 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 pCP013117_00101 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP013117_00101 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pCP013117_00102 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP013117_00102 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain GTP_EFTU PF00009.27 pCP013117_00104 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP013117_00104 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP013117_00104 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP013117_00104 - 1.3e-12 47.6 0.1 2.9e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP013117_00104 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP013117_00104 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP013117_00104 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP013117_00104 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP013117_00104 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPT PF07931.12 pCP013117_00105 - 1e-05 25.5 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 pCP013117_00105 - 1.5e-05 25.6 0.0 2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pCP013117_00105 - 0.016 15.6 0.0 0.073 13.4 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_33 PF13671.6 pCP013117_00105 - 0.023 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain APH PF01636.23 pCP013117_00106 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP013117_00106 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP013117_00106 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP013117_00106 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP013117_00106 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP013117_00106 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP013117_00107 - 4.2e-51 174.0 0.1 4.8e-51 173.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Toprim_3 PF13362.6 pCP013735_00001 - 2.4e-08 34.2 0.1 6.4e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP013735_00001 - 0.016 15.5 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP013735_00001 - 0.055 13.6 8.2 1.3 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pCP013735_00001 - 0.33 11.6 2.5 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP013735_00002 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP013735_00002 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 pCP013735_00003 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 pCP013735_00004 - 2.6e-30 105.7 7.7 4.2e-30 105.0 7.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pCP013735_00004 - 1.6e-26 93.2 0.7 2.2e-26 92.7 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pCP013735_00004 - 4.7e-06 25.6 0.7 7e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 pCP013735_00004 - 0.0036 17.4 0.7 0.012 15.7 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) ORC6 PF05460.13 pCP013735_00004 - 0.011 15.0 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HicB_lk_antitox PF15919.5 pCP013735_00006 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP013735_00006 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 pCP013735_00007 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP013735_00007 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP013735_00007 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP013735_00007 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP013735_00007 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP013735_00007 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pCP013735_00008 - 0.011 15.6 0.4 0.022 14.6 0.4 1.5 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pCP013735_00010 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP013735_00010 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP013735_00010 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP013735_00010 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP013735_00011 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP013735_00011 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP013735_00013 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP013735_00013 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP013735_00014 - 7.6e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP013735_00014 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP013735_00014 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP013735_00014 - 0.038 14.1 5.5 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pCP013735_00015 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP013735_00015 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP013735_00015 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP013735_00015 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP013735_00015 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 pCP013735_00016 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 pCP013735_00017 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP013735_00018 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP013735_00018 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP013735_00018 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP013735_00018 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP013735_00019 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP013735_00019 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP013735_00019 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP013735_00019 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP013735_00019 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 pCP013735_00019 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 pCP013735_00019 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pCP013735_00019 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pCP013735_00020 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP013735_00020 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP013735_00020 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP013735_00021 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP013735_00021 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP013735_00022 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP013735_00022 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP013735_00023 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP013735_00023 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP013735_00024 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP013735_00024 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP013735_00025 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP013735_00025 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP013735_00025 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP013735_00025 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP013735_00025 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP013735_00025 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP013735_00025 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP013735_00025 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP013735_00025 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP013735_00025 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP013735_00025 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP013735_00025 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP013735_00025 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP013735_00025 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP013735_00025 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP013735_00025 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP013735_00025 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP013735_00025 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP013735_00025 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP013735_00025 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP013735_00025 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP013735_00025 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP013735_00025 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP013735_00025 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP013735_00025 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP013735_00025 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP013735_00025 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP013735_00025 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP013735_00025 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP013735_00025 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP013735_00025 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP013735_00026 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP013735_00026 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP013735_00026 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP013735_00026 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP013735_00027 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP013735_00027 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP013735_00027 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP013735_00028 - 8.4e-36 123.3 1.7 1.1e-35 122.9 1.7 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP013735_00029 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Redoxin PF08534.10 pCP013735_00031 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP013735_00032 - 1.1e-97 327.7 8.1 1.6e-97 327.2 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP013735_00032 - 4.4e-12 46.1 2.6 6.4e-12 45.6 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP013735_00032 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP013735_00032 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP013735_00032 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP013735_00032 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP013735_00032 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP013735_00032 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP013735_00032 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP013735_00032 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP013735_00032 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP013735_00032 - 0.43 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP013735_00032 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP013735_00032 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP013735_00032 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP013735_00032 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP013735_00032 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP013735_00033 - 0.00012 22.0 2.7 0.00031 20.6 2.7 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP013735_00033 - 0.035 14.0 4.6 0.25 11.3 4.6 2.5 1 1 0 1 1 1 0 Intein splicing domain Ribonuc_2-5A PF06479.12 pCP013735_00034 - 0.022 14.9 1.5 0.03 14.5 1.5 1.5 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF5311 PF17238.2 pCP013735_00034 - 0.053 13.4 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5311) T6SS-SciN PF12790.7 pCP014345_00001 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pCP014345_00002 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pCP014345_00003 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pCP014345_00004 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pCP014345_00005 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pCP014345_00005 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pCP014345_00005 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pCP014345_00005 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pCP014345_00005 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pCP014345_00005 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pCP014345_00005 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pCP014345_00006 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pCP014345_00006 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pCP014345_00006 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF2974 PF11187.8 pCP014345_00010 - 3.9e-08 33.1 0.1 1e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 pCP014345_00010 - 6.3e-08 32.6 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 pCP014345_00010 - 3.1e-05 23.6 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pCP014345_00010 - 4.2e-05 23.4 0.4 0.00085 19.1 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 pCP014345_00010 - 0.00084 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pCP014345_00010 - 0.0016 19.1 0.0 0.0022 18.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pCP014345_00010 - 0.0033 17.4 0.1 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 pCP014345_00010 - 0.036 13.6 1.9 0.045 13.3 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4450) SBDS PF01172.18 pCP014345_00010 - 0.11 12.6 1.6 0.82 9.8 1.5 2.7 1 1 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Lipase_3 PF01764.25 pCP014345_00012 - 1.5e-08 34.6 0.0 5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pCP014345_00012 - 3.1e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pCP014345_00012 - 1.1e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pCP014345_00012 - 5.6e-05 23.0 0.1 9.7e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 pCP014345_00012 - 0.00041 20.0 0.1 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pCP014345_00012 - 0.00064 20.4 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pCP014345_00012 - 0.0014 18.6 0.3 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 pCP014345_00012 - 0.014 15.3 1.8 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase NMT PF01233.19 pCP014345_00012 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Hydrolase_4 PF12146.8 pCP014345_00012 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 pCP014345_00012 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF2070 PF09843.9 pCP014345_00013 - 0.082 11.2 10.5 0.094 11.0 10.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 pCP014345_00013 - 0.094 13.1 17.4 0.35 11.2 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 pCP014345_00013 - 0.2 11.0 22.9 4.3 6.6 6.7 2.4 1 1 1 2 2 2 0 Glucosyl transferase GtrII ABC2_membrane_5 PF13346.6 pCP014345_00013 - 0.31 10.5 21.7 0.023 14.2 5.5 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF5385 PF17359.2 pCP014345_00013 - 0.4 10.2 9.3 0.085 12.4 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF3784 PF12650.7 pCP014345_00013 - 4.8 7.4 22.3 0.22 11.7 8.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) RseC_MucC PF04246.12 pCP014345_00014 - 9.1 6.3 6.3 2.4 8.1 3.1 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AAA_31 PF13614.6 pCP014345_00016 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP014345_00016 - 0.0018 18.3 0.5 0.016 15.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP014345_00016 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pCP014345_00017 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pCP014345_00017 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal OrfB_IS605 PF01385.19 pCP014345_00018 - 1.8e-12 47.5 1.0 2.5e-12 47.1 1.0 1.2 1 0 0 1 1 1 1 Probable transposase AAA_25 PF13481.6 pCP014345_00019 - 2.9e-15 56.3 0.0 6.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP014345_00019 - 0.00024 20.5 0.0 0.01 15.2 0.0 2.4 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP014345_00019 - 0.0012 18.6 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP014345_00019 - 0.0029 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP014345_00019 - 0.0041 16.5 0.1 0.03 13.7 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP014345_00019 - 0.053 13.9 0.8 0.67 10.4 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP014345_00019 - 0.16 12.1 0.8 0.49 10.5 0.8 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicA_toxin PF07927.12 pCP014345_00020 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP014345_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Peptidase_M4_C PF02868.15 pCP014345_00022 - 0.051 13.4 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain AAA_31 PF13614.6 pCP014345_00025 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP014345_00025 - 0.0018 18.3 0.5 0.016 15.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP014345_00025 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pCP014345_00026 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pCP014345_00026 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal NYN PF01936.18 pCP014345_00028 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pCP014345_00028 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pCP014345_00028 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain Toprim_3 PF13362.6 pCP014345_00030 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP014345_00030 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP014345_00030 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pCP014345_00030 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Put_DNA-bind_N PF06971.13 pCP014345_00032 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus BLOC1_2 PF10046.9 pCP014345_00033 - 0.049 13.9 1.0 0.25 11.7 1.0 2.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2459 PF09601.10 pCP014345_00033 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) SseC PF04888.12 pCP014345_00036 - 0.005 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 pCP014345_00036 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pCP014345_00036 - 0.036 14.0 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 pCP014345_00036 - 0.061 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UvrA_DNA-bind PF17755.1 pCP014345_00037 - 0.008 16.5 0.4 2.8 8.3 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain Glyco_tranf_2_5 PF13712.6 pCP014345_00038 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 pCP014345_00039 - 1.5e-38 132.9 22.2 1.5e-38 132.9 22.2 2.3 2 1 1 3 3 3 1 TraG-like protein, N-terminal region CHMI PF02962.15 pCP014345_00039 - 0.0083 16.5 0.0 0.057 13.8 0.0 2.6 1 1 0 1 1 1 1 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 pCP014345_00041 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pCP014345_00041 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 pCP014345_00041 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 pCP014345_00041 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 pCP014345_00043 - 8.6e-09 35.6 0.3 0.00036 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pCP014345_00043 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 pCP014345_00044 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 pCP014345_00046 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 pCP014345_00046 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein Pox_J1 PF03338.15 pCP014345_00047 - 0.0028 17.5 1.7 0.096 12.5 0.1 2.5 2 1 0 2 2 2 2 Poxvirus J1 protein DHHA1 PF02272.19 pCP014345_00047 - 0.85 10.0 3.4 1.7 9.1 3.2 1.6 1 1 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 pCP014345_00048 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 pCP014345_00049 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pCP014345_00049 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pCP014345_00049 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 pCP014345_00051 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 pCP014345_00051 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 pCP014345_00052 - 7.5e-25 87.7 1.9 1.4e-24 86.8 0.2 2.2 2 1 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.8 pCP014345_00052 - 0.00023 21.3 0.1 0.0011 19.2 0.1 2.2 2 0 0 2 2 2 1 IMS family HHH motif CooC_C PF15976.5 pCP014345_00054 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 pCP014345_00054 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 pCP014345_00055 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pCP014345_00055 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pCP014345_00055 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pCP014345_00055 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 pCP014345_00055 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 pCP014345_00055 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pCP014345_00055 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pCP014345_00055 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pCP014345_00055 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pCP014345_00055 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pCP014345_00055 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pCP014345_00055 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pCP014345_00055 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 pCP014345_00055 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 pCP014345_00055 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 pCP014345_00055 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 pCP014345_00055 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 pCP014345_00055 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pCP014345_00055 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pCP014345_00055 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 pCP014345_00057 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 pCP014345_00057 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Occludin_ELL PF07303.13 pCP014345_00060 - 0.0057 17.4 1.0 0.0076 17.0 1.0 1.1 1 0 0 1 1 1 1 Occludin homology domain DUF2935 PF11155.8 pCP014345_00060 - 0.019 15.3 1.9 0.023 15.0 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) HAUS4 PF14735.6 pCP014345_00060 - 0.038 13.7 0.1 0.044 13.5 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF2207 PF09972.9 pCP014345_00060 - 0.19 10.5 2.4 0.2 10.4 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_NinH PF06322.11 pCP014345_00061 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein YafQ_toxin PF15738.5 pCP014345_00065 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pCP014345_00065 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 pCP014345_00065 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 pCP014345_00065 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system WGR PF05406.15 pCP014345_00070 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pCP014345_00070 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 pCP014345_00071 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 pCP014345_00072 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pCP014345_00072 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pCP014345_00072 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pCP014345_00072 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 pCP014345_00072 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 pCP014345_00072 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 pCP014345_00072 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Prok-TraM PF09228.10 pCP014345_00074 - 0.087 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 pCP014345_00074 - 2.3 8.5 10.7 0.22 11.8 0.4 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 pCP014345_00075 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 pCP014345_00076 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pCP014345_00076 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pCP014345_00076 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 pCP014345_00078 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pCP014345_00078 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 pCP014345_00080 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 pCP014345_00082 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 pCP014345_00082 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 pCP014345_00082 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 pCP014345_00084 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 pCP014345_00085 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 pCP014345_00085 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 pCP014345_00085 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 pCP014345_00085 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myc-LZ PF02344.15 pCP014345_00086 - 0.045 13.9 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Myc leucine zipper domain Importin_rep PF18773.1 pCP014345_00087 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 pCP014345_00087 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 pCP014345_00087 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 pCP014345_00088 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pCP014345_00088 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pCP014345_00089 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pCP014345_00090 - 1.6e-110 370.4 0.0 1.8e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pCP014345_00091 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pCP014345_00091 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pCP014345_00091 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pCP014345_00092 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pCP014345_00092 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pCP014345_00093 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pCP014345_00093 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pCP014345_00094 - 2.9e-12 46.6 0.0 4.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pCP014345_00094 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system TetR_C_24 PF17932.1 pCP014345_00094 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PX PF00787.24 pCP014345_00094 - 0.28 11.2 14.0 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain Phage_portal PF04860.12 pCP014569_00001 - 3.7e-29 101.9 0.1 4.8e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Phage portal protein DUF3770 PF12603.8 pCP014569_00001 - 0.036 13.6 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) Terminase_6 PF03237.15 pCP014569_00002 - 8.4e-17 61.6 0.0 1.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Terminase-like family Terminase_6C PF17289.2 pCP014569_00002 - 1.9e-07 31.3 0.0 4.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Terminase RNaseH-like domain HTH_Tnp_1 PF01527.20 pCP014569_00002 - 1.4e-06 28.5 0.2 4.1e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 pCP014569_00002 - 0.00044 20.2 0.0 0.034 14.2 0.0 3.5 3 1 1 4 4 4 1 Helix-turn-helix HTH_28 PF13518.6 pCP014569_00002 - 0.0027 17.8 0.0 0.0064 16.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 pCP014569_00002 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 pCP014569_00002 - 0.035 14.2 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 pCP014569_00002 - 0.061 13.1 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 pCP014569_00002 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Stirrup PF09061.6 pCP014569_00002 - 0.11 12.7 0.0 3.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Stirrup YajC PF02699.15 pCP014569_00004 - 0.044 13.7 0.0 0.045 13.6 0.0 1.0 1 0 0 1 1 1 0 Preprotein translocase subunit FeoB_associated PF12669.7 pCP014569_00004 - 0.057 13.8 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Phage_Mu_F PF04233.14 pCP014569_00007 - 1.2e-05 26.0 0.0 3.5e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Phage Mu protein F like protein SieB PF14163.6 pCP014569_00007 - 0.065 12.7 5.5 0.023 14.2 2.0 1.9 2 0 0 2 2 2 0 Super-infection exclusion protein B TFIID_NTD2 PF04494.15 pCP014569_00007 - 0.53 10.5 3.9 1 9.6 0.1 2.9 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain Zn_Tnp_IS1595 PF12760.7 pCP014569_00008 - 0.0013 18.7 1.5 0.0017 18.3 1.5 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.13 pCP014569_00008 - 0.0049 16.9 0.3 0.0058 16.7 0.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_KTR PF14205.6 pCP014569_00008 - 0.097 12.5 5.1 0.16 11.8 5.1 1.5 1 1 0 1 1 1 0 Cysteine-rich KTR DUF1018 PF06252.12 pCP014569_00009 - 0.02 15.8 0.1 0.036 15.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) OrfB_IS605 PF01385.19 pCP014569_00012 - 1.2e-24 86.8 0.2 1.2e-24 86.8 0.2 2.3 2 0 0 2 2 2 1 Probable transposase OrfB_Zn_ribbon PF07282.11 pCP014569_00012 - 3.3e-18 65.4 1.3 3.3e-18 65.4 1.3 1.8 2 0 0 2 2 2 1 Putative transposase DNA-binding domain VPS28 PF03997.12 pCP014569_00012 - 0.051 13.3 0.4 0.051 13.3 0.4 2.4 2 1 1 3 3 3 0 VPS28 protein HTH_OrfB_IS605 PF12323.8 pCP014569_00012 - 0.072 12.6 0.2 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Y1_Tnp PF01797.16 pCP014569_00013 - 1.5e-38 131.6 0.0 2.3e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Transposase IS200 like DUF1353 PF07087.11 pCP014569_00014 - 1.3e-18 66.4 0.0 1.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) ExsD PF16806.5 pCP014569_00015 - 0.0064 16.4 1.8 0.0096 15.9 1.8 1.2 1 0 0 1 1 1 1 Antiactivator protein ExsD CBM_X2 PF03442.14 pCP014569_00015 - 0.032 14.3 1.5 0.47 10.6 0.3 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain X2 YlqD PF11068.8 pCP014569_00015 - 0.052 13.9 4.1 0.084 13.2 4.1 1.4 1 0 0 1 1 1 0 YlqD protein HSBP1 PF06825.12 pCP014569_00015 - 0.065 13.1 0.4 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Spc7 PF08317.11 pCP014569_00015 - 0.098 11.5 10.1 0.14 11.0 10.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1465 PF07323.12 pCP014569_00015 - 0.11 12.4 1.1 0.18 11.6 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF1664 PF07889.12 pCP014569_00015 - 0.28 11.2 4.1 0.41 10.7 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4455 PF14643.6 pCP014569_00015 - 0.69 8.5 8.7 0.48 9.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) Atg14 PF10186.9 pCP014569_00015 - 0.79 8.7 7.5 2 7.4 7.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 pCP014569_00015 - 2.5 7.6 9.4 1.5 8.3 6.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DivIC PF04977.15 pCP014569_00016 - 0.24 11.2 0.1 0.24 11.2 0.1 2.6 1 1 2 3 3 3 0 Septum formation initiator Phage_holin_3_3 PF16083.5 pCP014569_00018 - 1.2e-10 41.3 4.9 1.6e-10 40.9 4.9 1.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III PG_binding_3 PF09374.10 pCP014569_00019 - 2.5e-11 43.7 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Predicted Peptidoglycan domain Glyco_hydro_108 PF05838.12 pCP014569_00019 - 5e-08 33.3 0.1 9.4e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase 108 MethyltransfD12 PF02086.15 pCP014569_00020 - 1.3e-28 100.4 4.0 2.2e-28 99.7 4.0 1.4 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Zea_mays_MuDR PF05928.11 pCP014569_00020 - 0.055 13.1 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) HTH_26 PF13443.6 pCP014569_00021 - 0.0001 22.7 0.1 0.66 10.4 0.0 3.1 2 1 1 3 3 3 2 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.6 pCP014569_00021 - 0.0042 17.2 0.0 1.5 9.0 0.0 3.3 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 pCP014569_00021 - 0.013 15.6 1.7 6.7 6.8 0.0 3.5 3 1 1 4 4 4 0 Helix-turn-helix Phage_terminase PF10668.9 pCP014569_00021 - 0.015 15.3 0.5 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Phage terminase small subunit DUF4004 PF13171.6 pCP014569_00021 - 0.021 15.1 3.4 9.3 6.4 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF4004) DUF2862 PF11061.8 pCP014569_00021 - 0.053 13.4 0.1 9.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) HTH_23 PF13384.6 pCP014569_00021 - 0.062 13.1 0.0 24 4.9 0.0 3.3 3 1 0 3 3 3 0 Homeodomain-like domain HTH_19 PF12844.7 pCP014569_00021 - 0.1 12.6 0.0 0.59 10.2 0.0 2.4 3 1 0 3 3 3 0 Helix-turn-helix domain AviRa PF11599.8 pCP014569_00021 - 0.11 12.0 0.0 4 6.8 0.0 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa YcxB PF14317.6 pCP014569_00021 - 0.16 11.7 2.8 4.1 7.2 0.1 2.5 2 1 0 2 2 2 0 YcxB-like protein DUF2569 PF10754.9 pCP014569_00024 - 0.026 15.0 0.4 0.042 14.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) PMT_4TMC PF16192.5 pCP014569_00024 - 0.06 12.9 0.3 0.083 12.5 0.3 1.2 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase NiFe_hyd_3_EhaA PF17367.2 pCP014569_00024 - 0.14 12.3 3.0 0.1 12.8 1.1 1.7 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A SHE3 PF17078.5 pCP014569_00025 - 0.0065 16.2 10.7 0.0078 16.0 10.7 1.0 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 F420_oxidored PF03807.17 pCP014569_00025 - 0.009 16.6 0.5 0.011 16.3 0.5 1.2 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent SKIP_SNW PF02731.15 pCP014569_00025 - 0.031 13.9 2.1 0.042 13.5 2.1 1.1 1 0 0 1 1 1 0 SKIP/SNW domain EutB PF06751.11 pCP014569_00025 - 0.037 12.8 0.6 0.039 12.8 0.6 1.0 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) FB_lectin PF07367.11 pCP014569_00025 - 0.072 13.0 0.3 0.094 12.7 0.3 1.1 1 0 0 1 1 1 0 Fungal fruit body lectin MCC-bdg_PDZ PF10506.9 pCP014569_00025 - 0.13 12.3 6.4 0.078 13.0 3.1 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF737 PF05300.11 pCP014569_00025 - 0.35 11.2 6.5 0.43 10.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) COX8 PF02285.15 pCP014569_00027 - 0.016 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII O-antigen_lig PF13425.6 pCP014569_00028 - 0.0041 16.0 3.8 0.0059 15.4 3.8 1.2 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Insulin_TMD PF17870.1 pCP014569_00028 - 0.035 14.2 1.3 0.035 14.2 1.3 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment TMEM51 PF15345.6 pCP014569_00028 - 0.079 12.8 0.1 0.13 12.1 0.1 1.3 1 1 0 1 1 1 0 Transmembrane protein 51 RRXRR PF14239.6 pCP014569_00031 - 1.5e-55 187.8 5.1 2e-55 187.3 5.1 1.2 1 0 0 1 1 1 1 RRXRR protein HNH_5 PF14279.6 pCP014569_00031 - 4e-12 45.8 1.5 7.1e-12 45.0 1.5 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 pCP014569_00031 - 4.7e-09 36.3 3.1 9e-09 35.4 3.1 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 pCP014569_00031 - 8.2e-09 35.2 0.1 2.4e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease DUF325 PF03804.13 pCP014569_00032 - 0.17 11.9 0.9 0.36 10.9 0.3 1.9 2 0 0 2 2 2 0 Viral proteins of unknown function Yae1_N PF09811.9 pCP014569_00033 - 0.41 10.4 1.9 0.6 9.9 0.7 1.7 2 0 0 2 2 2 0 Essential protein Yae1, N terminal DUF1411 PF07199.11 pCP014569_00034 - 0.2 11.3 8.9 0.024 14.3 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) HdeA PF06411.11 pCP014569_00035 - 0.057 13.6 0.2 0.087 13.0 0.2 1.3 1 0 0 1 1 1 0 HdeA/HdeB family FAM76 PF16046.5 pCP014569_00037 - 0.24 10.7 30.5 0.067 12.5 21.6 2.0 1 1 1 2 2 2 0 FAM76 protein UCH PF00443.29 pCP014569_00037 - 0.42 10.1 17.0 0.026 14.0 2.2 2.7 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF4806 PF16064.5 pCP014569_00037 - 0.55 10.6 10.9 0.24 11.7 1.1 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4806) DUF4665 PF15679.5 pCP014569_00037 - 2.5 8.7 34.7 1 10.0 5.6 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) Chlorosome_CsmC PF11098.8 pCP014569_00038 - 0.0041 17.1 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Chlorosome envelope protein C Tup_N PF08581.10 pCP014569_00038 - 0.017 15.4 1.7 0.017 15.4 1.7 3.1 1 1 1 2 2 2 0 Tup N-terminal CBP_BcsR PF10945.8 pCP014569_00038 - 0.031 13.7 0.3 0.067 12.7 0.3 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Spectrin_like PF18373.1 pCP014569_00038 - 0.033 14.3 3.6 0.23 11.6 0.3 3.0 1 1 2 3 3 3 0 Spectrin like domain APG6_N PF17675.1 pCP014569_00038 - 0.042 14.4 6.1 0.28 11.7 0.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 pCP014569_00038 - 0.059 12.6 6.3 0.097 11.9 2.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 pCP014569_00038 - 0.099 12.9 2.4 0.25 11.6 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PSD3 PF07626.11 pCP014569_00038 - 0.14 12.7 0.1 0.23 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) SKA2 PF16740.5 pCP014569_00038 - 0.25 11.1 7.9 0.71 9.7 6.6 2.1 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 pCP014569_00038 - 0.53 10.8 6.0 12 6.5 6.1 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 pCP014569_00038 - 0.55 11.0 3.8 13 6.6 0.2 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2203 PF09969.9 pCP014569_00038 - 1.2 9.9 4.2 10 6.9 1.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ZapB PF06005.12 pCP014569_00038 - 2.7 8.5 8.5 8.5 6.9 8.2 2.0 1 1 1 2 2 2 0 Cell division protein ZapB Phasin PF05597.11 pCP014569_00039 - 0.17 11.9 9.3 0.68 9.9 1.9 2.6 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF948 PF06103.11 pCP014569_00039 - 0.47 10.7 5.0 2.7 8.3 0.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 pCP014569_00039 - 0.47 11.1 2.2 6.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MutS_III PF05192.18 pCP014569_00039 - 0.56 10.4 5.4 0.64 10.2 5.4 1.2 1 0 0 1 1 1 0 MutS domain III Bravo_FIGEY PF13882.6 pCP014569_00039 - 1.2 10.5 7.1 0.61 11.5 4.1 2.0 2 0 0 2 2 2 0 Bravo-like intracellular region YtxH PF12732.7 pCP014569_00039 - 2.5 8.7 21.0 0.11 13.1 2.6 3.2 3 0 0 3 3 3 0 YtxH-like protein HEPN_RES_NTD1 PF18870.1 pCP014569_00039 - 4.2 7.6 8.3 7.5 6.8 0.4 3.0 1 1 1 3 3 3 0 HEPN/RES N-terminal domain 1 SLT PF01464.20 pCP014569_00040 - 8.9e-12 44.7 0.0 1.4e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 Transglycosylase SLT domain Leukocidin PF07968.12 pCP014569_00040 - 0.00012 22.1 0.2 0.0002 21.3 0.2 1.4 1 0 0 1 1 1 1 Leukocidin/Hemolysin toxin family Glucosaminidase PF01832.20 pCP014569_00040 - 0.2 12.2 2.1 0.27 11.8 2.1 1.5 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase AAA_22 PF13401.6 pCP014569_00041 - 0.14 12.4 0.0 6.7 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF226 PF02890.14 pCP014569_00042 - 0.017 15.1 0.9 0.017 15.1 0.9 3.2 3 1 0 3 3 3 0 Borrelia family of unknown function DUF226 Y1_Tnp PF01797.16 pCP014569_00043 - 1.5e-38 131.6 0.0 2.3e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Transposase IS200 like OrfB_IS605 PF01385.19 pCP014569_00044 - 1.2e-24 86.8 0.2 1.2e-24 86.8 0.2 2.3 2 0 0 2 2 2 1 Probable transposase OrfB_Zn_ribbon PF07282.11 pCP014569_00044 - 3.3e-18 65.4 1.3 3.3e-18 65.4 1.3 1.8 2 0 0 2 2 2 1 Putative transposase DNA-binding domain VPS28 PF03997.12 pCP014569_00044 - 0.051 13.3 0.4 0.051 13.3 0.4 2.4 2 1 1 3 3 3 0 VPS28 protein HTH_OrfB_IS605 PF12323.8 pCP014569_00044 - 0.073 12.6 0.2 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain CshA_NR2 PF18651.1 pCP014569_00046 - 0.099 11.8 0.2 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Surface adhesin CshA non-repetitive domain 2 DUF3603 PF12227.8 pCP014569_00048 - 0.3 10.4 3.1 0.27 10.5 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) DUF2357 PF09823.9 pCP014569_00049 - 0.098 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) ThylakoidFormat PF11264.8 pCP014569_00049 - 0.24 11.0 2.1 1.8 8.2 2.1 2.0 1 1 0 1 1 1 0 Thylakoid formation protein DUF4214 PF13946.6 pCP014569_00051 - 0.0004 20.4 4.0 0.00042 20.3 0.1 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4214) DUF3784 PF12650.7 pCP014569_00052 - 0.0045 17.2 0.7 0.0048 17.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3784) TMCCDC2 PF15844.5 pCP014569_00052 - 0.021 14.7 0.7 0.021 14.7 0.7 1.1 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 DUF1240 PF06836.12 pCP014569_00052 - 0.052 14.1 1.8 0.13 12.8 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) DUF2321 PF10083.9 pCP014569_00053 - 0.05 13.2 0.1 0.053 13.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Phage_cap_P2 PF05125.12 pCP014569_00058 - 9.9e-08 31.3 2.5 2e-06 27.0 2.5 2.1 1 1 0 1 1 1 1 Phage major capsid protein, P2 family Tctex-1 PF03645.13 pCP014569_00058 - 0.014 15.7 1.3 0.14 12.4 0.0 2.9 2 2 0 2 2 2 0 Tctex-1 family Peptidase_S78_2 PF14550.6 pCP014569_00059 - 7.4e-34 116.4 0.1 1.2e-33 115.8 0.1 1.3 1 0 0 1 1 1 1 Putative phage serine protease XkdF Holin_BhlA PF10960.8 pCP014569_00059 - 0.026 14.5 1.7 0.061 13.3 1.7 1.6 1 0 0 1 1 1 0 BhlA holin family Abi_C PF14355.6 pCP014569_00059 - 0.059 13.5 0.7 13 6.0 0.0 3.2 2 1 1 3 3 3 0 Abortive infection C-terminus DUF2203 PF09969.9 pCP014569_00059 - 0.26 12.0 1.8 0.46 11.2 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4391 PF14335.6 pCP014569_00059 - 0.29 10.8 5.2 0.66 9.6 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) SPT16 PF08644.11 pCP014569_00059 - 0.58 10.3 3.5 0.87 9.8 0.8 2.4 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Prok-TraM PF09228.10 pCP014743_00001 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 pCP014743_00001 - 3 8.1 11.1 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 pCP014743_00002 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 pCP014743_00003 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pCP014743_00003 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pCP014743_00003 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 pCP014743_00005 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pCP014743_00005 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 pCP014743_00007 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 pCP014743_00009 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 pCP014743_00009 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 pCP014743_00009 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 pCP014743_00011 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 pCP014743_00012 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 pCP014743_00012 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 pCP014743_00012 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 pCP014743_00012 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Importin_rep PF18773.1 pCP014743_00013 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 pCP014743_00013 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 pCP014743_00013 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 pCP014743_00014 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pCP014743_00014 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pCP014743_00015 - 3.5e-47 161.1 0.0 3.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pCP014743_00016 - 2.2e-110 370.0 0.0 2.5e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pCP014743_00017 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pCP014743_00017 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pCP014743_00017 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pCP014743_00018 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pCP014743_00018 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pCP014743_00019 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pCP014743_00019 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pCP014743_00020 - 1.2e-12 47.9 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pCP014743_00020 - 0.00013 22.0 0.2 0.00079 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pCP014743_00020 - 0.0034 17.4 13.8 0.059 13.3 1.9 4.2 3 2 0 3 3 3 2 PX domain T6SS-SciN PF12790.7 pCP014743_00021 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pCP014743_00022 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pCP014743_00023 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pCP014743_00024 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pCP014743_00025 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pCP014743_00025 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pCP014743_00025 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pCP014743_00025 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pCP014743_00025 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pCP014743_00025 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pCP014743_00025 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pCP014743_00026 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pCP014743_00026 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pCP014743_00026 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3870 PF12986.7 pCP014743_00027 - 0.098 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) DUF2459 PF09601.10 pCP014743_00030 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) BLOC1_2 PF10046.9 pCP014743_00030 - 0.1 12.9 2.0 0.25 11.7 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_DNA-bind_N PF06971.13 pCP014743_00031 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Toprim_3 PF13362.6 pCP014743_00032 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP014743_00032 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP014743_00032 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pCP014743_00032 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold NYN PF01936.18 pCP014743_00034 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pCP014743_00034 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pCP014743_00034 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain PTS-HPr PF00381.19 pCP014743_00035 - 0.17 12.1 0.0 0.19 12.0 0.0 1.0 1 0 0 1 1 1 0 PTS HPr component phosphorylation site RHH_7 PF16777.5 pCP014743_00036 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pCP014743_00036 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 pCP014743_00037 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP014743_00037 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP014743_00037 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pCP014743_00037 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP014743_00038 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP014743_00038 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP014743_00039 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP014743_00039 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP014743_00039 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP014743_00039 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP014743_00039 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP014743_00040 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP014743_00040 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP014743_00040 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP014743_00040 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP014743_00040 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP014743_00040 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP014743_00040 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pCP014743_00041 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 pCP014743_00042 - 0.047 13.8 0.3 4.4 7.5 0.0 2.3 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pCP014743_00043 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP014743_00043 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Asp-B-Hydro_N PF05279.11 pCP014743_00045 - 2.9 7.9 12.2 3.4 7.7 12.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GTP_EFTU PF00009.27 pCP014743_00046 - 8.1e-59 198.4 0.4 1.1e-58 198.0 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP014743_00046 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP014743_00046 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP014743_00046 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP014743_00046 - 1.8e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP014743_00046 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP014743_00046 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP014743_00046 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP014743_00046 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pCP014743_00048 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP014743_00048 - 0.022 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pCP014743_00049 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP014743_00049 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP014743_00049 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP014743_00049 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP014743_00049 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP014743_00049 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP014743_00049 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP014743_00049 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP014743_00049 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP014743_00049 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP014743_00049 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP014743_00049 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP014743_00049 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP014743_00049 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP014743_00049 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP014743_00049 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP014743_00049 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pCP014743_00050 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP014743_00051 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP014743_00051 - 0.077 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP014743_00051 - 0.74 9.8 5.2 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCP014743_00052 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP014743_00053 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP014743_00053 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP014743_00053 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP014743_00053 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCP014743_00054 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP014743_00054 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP014743_00054 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP014743_00054 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Phage_pRha PF09669.10 pCP014743_00055 - 3.4e-21 75.6 0.1 3.4e-21 75.6 0.1 2.0 2 1 0 2 2 2 1 Phage regulatory protein Rha (Phage_pRha) T2SSE PF00437.20 pCP014743_00056 - 6.4e-54 182.8 0.0 7.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP014743_00056 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP014743_00056 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP014743_00056 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP014743_00056 - 0.0014 18.9 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP014743_00056 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP014743_00056 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP014743_00056 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP014743_00056 - 0.0049 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP014743_00056 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP014743_00056 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP014743_00056 - 0.0088 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP014743_00056 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP014743_00056 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP014743_00056 - 0.022 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP014743_00056 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP014743_00056 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP014743_00056 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP014743_00056 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP014743_00056 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP014743_00056 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP014743_00056 - 0.039 13.2 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP014743_00056 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP014743_00056 - 0.063 11.9 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP014743_00056 - 0.065 13.6 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP014743_00056 - 0.085 12.8 0.4 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP014743_00056 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP014743_00056 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP014743_00056 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP014743_00056 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP014743_00056 - 0.29 11.6 3.1 0.32 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP014743_00057 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP014743_00057 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP014743_00058 - 6.2e-55 186.2 1.7 1e-54 185.5 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP014743_00058 - 0.082 12.7 0.3 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCP014743_00059 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP014743_00059 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP014743_00060 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP014743_00060 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP014743_00061 - 2.7e-29 102.5 30.5 2.7e-29 102.5 30.5 1.5 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP014743_00061 - 0.21 11.4 1.5 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered T4SS PF07996.11 pCP014743_00062 - 1.9e-28 100.2 13.4 2.7e-28 99.7 13.4 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP014743_00062 - 0.0072 16.4 1.8 0.021 15.0 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP014743_00062 - 0.0092 16.7 6.0 0.0092 16.7 6.0 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP014743_00062 - 0.072 13.8 1.0 0.072 13.8 1.0 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pCP014743_00062 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pCP014743_00062 - 2.3 8.7 8.3 9.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) WXG100 PF06013.12 pCP014743_00062 - 7.2 6.9 12.9 1 9.7 0.7 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG IF2_N PF04760.15 pCP014743_00063 - 6.5e-05 22.7 5.8 0.00049 19.9 2.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HTH_16 PF12645.7 pCP014743_00063 - 0.013 15.5 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP014743_00063 - 0.029 15.1 0.5 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor FliG_N PF14842.6 pCP014743_00063 - 0.039 14.5 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain SSB PF00436.25 pCP014743_00064 - 2.5e-24 85.3 0.1 3.2e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family FapA PF03961.13 pCP014743_00065 - 0.072 11.7 13.7 0.0066 15.1 7.2 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3251 PF11622.8 pCP014743_00065 - 0.085 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Fib_alpha PF08702.10 pCP014743_00065 - 1.1 9.4 11.4 0.062 13.5 3.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 pCP014743_00065 - 1.8 8.9 13.9 1 9.7 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP014743_00065 - 4.4 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Ax_dynein_light PF10211.9 pCP014743_00065 - 4.5 7.2 15.1 0.051 13.5 3.7 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain Phage_pRha PF09669.10 pCP014743_00066 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) CagE_TrbE_VirB PF03135.14 pCP014743_00067 - 9.3e-49 166.3 0.3 2.3e-48 165.0 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP014743_00067 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP014743_00067 - 1.5e-07 30.7 0.8 3.5e-07 29.5 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP014743_00067 - 0.039 14.0 5.4 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 pCP014743_00068 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP014743_00068 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP014743_00070 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP014743_00070 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pCP014743_00071 - 9.1e-32 110.2 0.6 1.2e-31 109.8 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP014743_00071 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP014743_00071 - 0.065 13.3 4.7 0.68 10.0 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP014743_00071 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pCP014743_00072 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP014743_00072 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP014743_00072 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP014743_00072 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP014743_00072 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP014743_00072 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP014743_00072 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicA_toxin PF07927.12 pCP014743_00073 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP014743_00074 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCP014743_00075 - 0.0043 17.1 1.7 0.0054 16.8 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 pCP014743_00075 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 pCP014743_00076 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP014743_00076 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pCP014743_00077 - 2.1e-08 34.4 0.0 4.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP014743_00077 - 0.088 12.8 0.8 0.37 10.8 0.3 2.3 2 0 0 2 2 2 0 PAZ domain 5_3_exonuc PF01367.20 pCP014743_00077 - 0.17 12.5 4.7 0.89 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pCP014743_00078 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 pCP014743_00080 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP014743_00080 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP014743_00080 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCP014743_00081 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP014743_00081 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP014743_00081 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP014743_00081 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP014743_00081 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 pCP014743_00082 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 pCP014743_00083 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pCP014743_00083 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCP014743_00083 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCP014743_00083 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pCP014743_00083 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP014743_00083 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pCP014743_00083 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 pCP014743_00083 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 pCP014743_00083 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 pCP014743_00083 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 pCP014743_00083 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pCP014743_00083 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 pCP014743_00083 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 pCP014743_00083 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain SNF2_N PF00176.23 pCP014743_00084 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP014743_00084 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP014743_00084 - 9.4e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP014743_00084 - 1.3e-05 25.0 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP014743_00084 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP014743_00085 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCP014743_00086 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP014743_00086 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP014743_00086 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase NnrS PF05940.12 pCP014743_00088 - 0.023 14.1 9.9 0.028 13.8 9.9 1.0 1 0 0 1 1 1 0 NnrS protein DUF2070 PF09843.9 pCP014743_00088 - 0.054 11.8 13.4 0.063 11.6 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 pCP014743_00088 - 0.15 12.4 19.9 0.53 10.7 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 pCP014743_00088 - 0.51 9.7 27.0 0.49 9.7 7.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF5385 PF17359.2 pCP014743_00088 - 0.52 9.8 9.3 0.099 12.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NVEALA PF14055.6 pCP014743_00088 - 4.1 7.4 6.4 4.2 7.4 0.2 2.9 1 1 2 3 3 3 0 NVEALA protein TssN PF17555.2 pCP014743_00088 - 4.7 6.5 20.7 5.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2663 PF10864.8 pCP014743_00088 - 6.7 7.1 10.9 36 4.8 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Lipase_3 PF01764.25 pCP014743_00089 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pCP014743_00089 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 pCP014743_00089 - 2.7e-05 24.0 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 pCP014743_00089 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 pCP014743_00089 - 0.00045 19.9 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pCP014743_00089 - 0.0017 19.0 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pCP014743_00089 - 0.0021 18.1 0.9 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 pCP014743_00089 - 0.016 14.8 0.1 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF1257 PF06868.11 pCP014743_00089 - 0.24 11.7 2.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) SBDS PF01172.18 pCP014743_00089 - 0.79 9.8 5.3 0.83 9.8 1.4 3.2 2 2 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein SseC PF04888.12 pCP014743_00092 - 0.0012 18.5 0.2 0.0032 17.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family APOBEC_C PF05240.14 pCP014743_00092 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ThrE PF06738.12 pCP014743_00092 - 0.019 14.3 0.8 0.051 12.9 0.8 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pCP014743_00092 - 0.033 14.1 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone PTS_EIIC_2 PF13303.6 pCP014743_00092 - 0.037 13.1 1.0 0.064 12.3 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC TPR_11 PF13414.6 pCP014743_00092 - 0.064 12.9 0.3 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 TPR repeat Glyco_tranf_2_5 PF13712.6 pCP014743_00094 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 pCP014743_00095 - 3.3e-42 144.9 22.9 3.3e-42 144.9 22.9 2.2 2 1 0 2 2 2 1 TraG-like protein, N-terminal region CHMI PF02962.15 pCP014743_00095 - 0.017 15.5 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 pCP014743_00098 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pCP014743_00098 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 pCP014743_00098 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 pCP014743_00098 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 pCP014743_00100 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pCP014743_00100 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 pCP014743_00101 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 pCP014743_00102 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 pCP014743_00102 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein DHHA1 PF02272.19 pCP014743_00103 - 0.18 12.2 1.6 0.37 11.2 1.6 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 pCP014743_00104 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 pCP014743_00105 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pCP014743_00105 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pCP014743_00105 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 pCP014743_00107 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 pCP014743_00107 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 pCP014743_00109 - 1.5e-25 89.9 0.2 4e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family CooC_C PF15976.5 pCP014743_00110 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 pCP014743_00110 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 pCP014743_00111 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pCP014743_00111 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pCP014743_00111 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pCP014743_00111 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 pCP014743_00111 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 pCP014743_00111 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pCP014743_00111 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pCP014743_00111 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pCP014743_00111 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pCP014743_00111 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pCP014743_00111 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pCP014743_00111 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pCP014743_00111 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 pCP014743_00111 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 pCP014743_00111 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 pCP014743_00111 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 pCP014743_00111 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 pCP014743_00111 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pCP014743_00111 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pCP014743_00111 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 pCP014743_00113 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 pCP014743_00113 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HSBP1 PF06825.12 pCP014743_00115 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 pCP014743_00115 - 0.026 14.9 0.3 0.039 14.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 pCP014743_00115 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 pCP014743_00115 - 0.11 12.8 0.3 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_NinH PF06322.11 pCP014743_00116 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein WGR PF05406.15 pCP014743_00120 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pCP014743_00120 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 pCP014743_00121 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 pCP014743_00122 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pCP014743_00122 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pCP014743_00122 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pCP014743_00122 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 pCP014743_00122 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 pCP014743_00122 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 pCP014743_00122 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Prok-TraM PF09228.10 pCP014745_00001 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 pCP014745_00001 - 3 8.1 11.1 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 pCP014745_00003 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 pCP014745_00004 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pCP014745_00004 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pCP014745_00004 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 pCP014745_00006 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pCP014745_00006 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 pCP014745_00008 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 DivIC PF04977.15 pCP014745_00009 - 0.0039 16.9 0.2 0.0039 16.9 0.2 3.7 4 0 0 4 4 4 1 Septum formation initiator HTH_48 PF17906.1 pCP014745_00009 - 0.043 13.9 0.2 5.5 7.2 0.0 3.0 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Nucleoside_tran PF01733.18 pCP014745_00011 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 pCP014745_00011 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 pCP014745_00011 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 pCP014745_00013 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 pCP014745_00014 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 pCP014745_00014 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 pCP014745_00014 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 pCP014745_00014 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Importin_rep PF18773.1 pCP014745_00015 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 pCP014745_00015 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 pCP014745_00015 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 pCP014745_00016 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pCP014745_00016 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pCP014745_00017 - 3.5e-47 161.1 0.0 3.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pCP014745_00018 - 1.6e-110 370.4 0.0 1.8e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pCP014745_00019 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pCP014745_00019 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pCP014745_00019 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pCP014745_00020 - 1.2e-169 564.6 0.0 1.4e-169 564.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pCP014745_00020 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pCP014745_00021 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pCP014745_00021 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pCP014745_00022 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pCP014745_00022 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pCP014745_00022 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 pCP014745_00022 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 pCP014745_00023 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pCP014745_00024 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pCP014745_00025 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pCP014745_00026 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pCP014745_00027 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pCP014745_00027 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pCP014745_00027 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pCP014745_00027 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pCP014745_00027 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pCP014745_00027 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pCP014745_00027 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pCP014745_00028 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pCP014745_00028 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pCP014745_00028 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3870 PF12986.7 pCP014745_00029 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Syntaxin-6_N PF09177.11 pCP014745_00030 - 6.8 7.3 10.5 44 4.7 3.3 4.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF2459 PF09601.10 pCP014745_00031 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) BLOC1_2 PF10046.9 pCP014745_00031 - 0.1 12.9 2.0 0.25 11.7 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_DNA-bind_N PF06971.13 pCP014745_00032 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Toprim_3 PF13362.6 pCP014745_00033 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP014745_00033 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP014745_00033 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pCP014745_00033 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pCP014745_00034 - 0.26 11.3 4.3 0.56 10.2 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) NYN PF01936.18 pCP014745_00035 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pCP014745_00035 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pCP014745_00035 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain RHH_7 PF16777.5 pCP014745_00037 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pCP014745_00037 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 pCP014745_00038 - 4.8e-05 23.3 0.6 0.00095 19.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP014745_00038 - 0.00043 20.3 0.7 0.0043 17.1 0.7 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP014745_00038 - 0.036 13.5 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP014745_00038 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP014745_00038 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP014745_00039 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP014745_00039 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP014745_00040 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP014745_00040 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP014745_00040 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP014745_00040 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP014745_00040 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP014745_00041 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP014745_00041 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP014745_00041 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP014745_00041 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP014745_00041 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP014745_00041 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP014745_00041 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain GTP_EFTU PF00009.27 pCP014745_00042 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP014745_00042 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP014745_00042 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP014745_00042 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP014745_00042 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP014745_00042 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP014745_00042 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP014745_00042 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP014745_00042 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pCP014745_00044 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP014745_00044 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 pCP014745_00045 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP014745_00045 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP014745_00045 - 1.7e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP014745_00045 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP014745_00045 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP014745_00045 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pCP014745_00045 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP014745_00045 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pCP014745_00045 - 0.088 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 pCP014745_00045 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP014745_00045 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP014745_00045 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP014745_00045 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP014745_00045 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP014745_00045 - 6.9 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP014745_00045 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pCP014745_00046 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP014745_00047 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP014745_00047 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP014745_00047 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pCP014745_00048 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP014745_00049 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP014745_00049 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP014745_00049 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP014745_00049 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pCP014745_00050 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP014745_00050 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP014745_00050 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP014745_00050 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pCP014745_00051 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP014745_00051 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP014745_00051 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP014745_00051 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP014745_00051 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP014745_00051 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP014745_00051 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP014745_00051 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP014745_00051 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP014745_00051 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP014745_00051 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP014745_00051 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP014745_00051 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP014745_00051 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP014745_00051 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP014745_00051 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP014745_00051 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP014745_00051 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP014745_00051 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP014745_00051 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP014745_00051 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP014745_00051 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP014745_00051 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP014745_00051 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP014745_00051 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP014745_00051 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP014745_00051 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP014745_00051 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP014745_00051 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP014745_00051 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP014745_00051 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP014745_00052 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP014745_00052 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP014745_00053 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP014745_00053 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pCP014745_00054 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP014745_00054 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP014745_00055 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP014745_00055 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP014745_00056 - 2.7e-31 109.0 32.0 2.7e-31 109.0 32.0 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein DUF3176 PF11374.8 pCP014745_00056 - 0.088 13.0 0.5 0.088 13.0 0.5 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF3176) T_cell_tran_alt PF15128.6 pCP014745_00056 - 0.18 11.6 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP014745_00056 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pCP014745_00057 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP014745_00057 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP014745_00057 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP014745_00057 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP014745_00057 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCP014745_00057 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pCP014745_00057 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pCP014745_00057 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pCP014745_00058 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP014745_00058 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP014745_00058 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP014745_00058 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP014745_00059 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 pCP014745_00060 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP014745_00060 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP014745_00060 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP014745_00060 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP014745_00060 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP014745_00060 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 pCP014745_00061 - 6.6e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP014745_00061 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 pCP014745_00061 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) CagE_TrbE_VirB PF03135.14 pCP014745_00062 - 4e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP014745_00062 - 3.7e-21 75.1 1.1 6.4e-21 74.4 1.1 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP014745_00062 - 4.4e-07 29.2 0.5 1e-06 28.0 0.5 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP014745_00062 - 0.0092 16.1 2.9 1.7 8.7 0.0 3.8 4 1 1 5 5 5 2 Helicase HerA, central domain TrbC PF04956.13 pCP014745_00063 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP014745_00063 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP014745_00065 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 CRISPR associated protein Cas2 Resolvase PF00239.21 pCP014745_00066 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP014745_00066 - 0.026 14.3 0.7 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP014745_00066 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_25 PF13481.6 pCP014745_00067 - 1.6e-14 54.0 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP014745_00067 - 0.00038 19.9 0.0 0.0018 17.6 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP014745_00067 - 0.0023 17.7 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP014745_00067 - 0.0089 15.4 0.0 0.058 12.7 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP014745_00067 - 0.009 16.4 0.2 0.22 11.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP014745_00067 - 0.16 12.0 1.6 0.74 9.9 1.6 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP014745_00067 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicB_lk_antitox PF15919.5 pCP014745_00068 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system UBA_6 PF18039.1 pCP014745_00069 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pCP014745_00069 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pCP014745_00069 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pCP014745_00069 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 pCP014745_00070 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP014745_00070 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pCP014745_00071 - 2.5e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP014745_00071 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP014745_00071 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP014745_00071 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pCP014745_00072 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) HisK_sensor PF18698.1 pCP014745_00073 - 0.052 13.9 1.6 0.072 13.5 1.6 1.3 1 1 0 1 1 1 0 Histidine kinase sensor domain SANT_DAMP1_like PF16282.5 pCP014745_00074 - 0.08 13.1 0.3 0.11 12.6 0.3 1.5 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Sds3 PF08598.11 pCP014745_00075 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP014745_00075 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP014745_00075 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCP014745_00076 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP014745_00076 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP014745_00076 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP014745_00076 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP014745_00076 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 pCP014745_00077 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 pCP014745_00078 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pCP014745_00078 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCP014745_00078 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCP014745_00078 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pCP014745_00078 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP014745_00078 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pCP014745_00078 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 pCP014745_00078 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 pCP014745_00078 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 pCP014745_00078 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 pCP014745_00078 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pCP014745_00078 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 pCP014745_00078 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 pCP014745_00078 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain SNF2_N PF00176.23 pCP014745_00079 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP014745_00079 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP014745_00079 - 9.4e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP014745_00079 - 1.3e-05 25.0 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP014745_00079 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP014745_00080 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCP014745_00081 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP014745_00081 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP014745_00081 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase NnrS PF05940.12 pCP014745_00083 - 0.023 14.1 9.9 0.028 13.8 9.9 1.0 1 0 0 1 1 1 0 NnrS protein DUF2070 PF09843.9 pCP014745_00083 - 0.054 11.8 13.4 0.063 11.6 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 pCP014745_00083 - 0.15 12.4 19.9 0.53 10.7 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 pCP014745_00083 - 0.51 9.7 27.0 0.49 9.7 7.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF5385 PF17359.2 pCP014745_00083 - 0.52 9.8 9.3 0.099 12.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NVEALA PF14055.6 pCP014745_00083 - 4.1 7.4 6.4 4.2 7.4 0.2 2.9 1 1 2 3 3 3 0 NVEALA protein TssN PF17555.2 pCP014745_00083 - 4.7 6.5 20.7 5.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2663 PF10864.8 pCP014745_00083 - 6.7 7.1 10.9 36 4.8 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Lipase_3 PF01764.25 pCP014745_00084 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pCP014745_00084 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 pCP014745_00084 - 2.7e-05 24.0 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 pCP014745_00084 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 pCP014745_00084 - 0.00045 19.9 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pCP014745_00084 - 0.0017 19.0 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pCP014745_00084 - 0.0021 18.1 0.9 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 pCP014745_00084 - 0.016 14.8 0.1 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF1257 PF06868.11 pCP014745_00084 - 0.24 11.7 2.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) SBDS PF01172.18 pCP014745_00084 - 0.79 9.8 5.3 0.83 9.8 1.4 3.2 2 2 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein SseC PF04888.12 pCP014745_00087 - 0.0012 18.5 0.2 0.0032 17.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family APOBEC_C PF05240.14 pCP014745_00087 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ThrE PF06738.12 pCP014745_00087 - 0.019 14.3 0.8 0.051 12.9 0.8 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pCP014745_00087 - 0.033 14.1 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone PTS_EIIC_2 PF13303.6 pCP014745_00087 - 0.037 13.1 1.0 0.064 12.3 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC TPR_11 PF13414.6 pCP014745_00087 - 0.064 12.9 0.3 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 TPR repeat Glyco_tranf_2_5 PF13712.6 pCP014745_00089 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 pCP014745_00090 - 3.3e-42 144.9 22.9 3.3e-42 144.9 22.9 2.2 2 1 0 2 2 2 1 TraG-like protein, N-terminal region CHMI PF02962.15 pCP014745_00090 - 0.017 15.5 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 pCP014745_00093 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pCP014745_00093 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 pCP014745_00093 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 pCP014745_00093 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 pCP014745_00095 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pCP014745_00095 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 pCP014745_00096 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 pCP014745_00097 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 pCP014745_00097 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein DHHA1 PF02272.19 pCP014745_00098 - 0.18 12.2 1.6 0.37 11.2 1.6 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 pCP014745_00099 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 pCP014745_00100 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pCP014745_00100 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pCP014745_00100 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 pCP014745_00102 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 pCP014745_00102 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 pCP014745_00104 - 1.5e-25 89.9 0.2 4e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family CooC_C PF15976.5 pCP014745_00105 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 pCP014745_00105 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 pCP014745_00106 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pCP014745_00106 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pCP014745_00106 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pCP014745_00106 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 pCP014745_00106 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 pCP014745_00106 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pCP014745_00106 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pCP014745_00106 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pCP014745_00106 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pCP014745_00106 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pCP014745_00106 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pCP014745_00106 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pCP014745_00106 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 pCP014745_00106 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 pCP014745_00106 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 pCP014745_00106 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 pCP014745_00106 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 pCP014745_00106 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pCP014745_00106 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pCP014745_00106 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 pCP014745_00108 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 pCP014745_00108 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HSBP1 PF06825.12 pCP014745_00110 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 pCP014745_00110 - 0.026 14.9 0.3 0.039 14.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 pCP014745_00110 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 pCP014745_00110 - 0.11 12.8 0.3 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_NinH PF06322.11 pCP014745_00111 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein WGR PF05406.15 pCP014745_00115 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pCP014745_00115 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 pCP014745_00116 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 pCP014745_00117 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pCP014745_00117 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pCP014745_00117 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pCP014745_00117 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 pCP014745_00117 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 pCP014745_00117 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 pCP014745_00117 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator IMS PF00817.20 pCP017026_00001 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family DUF4368 PF14287.6 pCP017026_00002 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 pCP017026_00002 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.4 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 pCP017026_00002 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 pCP017026_00002 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 pCP017026_00002 - 0.14 12.2 0.7 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Snapin_Pallidin PF14712.6 pCP017026_00002 - 1.2 9.6 6.0 13 6.3 0.2 2.9 3 0 0 3 3 3 0 Snapin/Pallidin TnpV PF14198.6 pCP017026_00003 - 3.3e-41 139.8 0.5 3.6e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV AAA_18 PF13238.6 pCP017026_00004 - 1.4e-14 54.8 0.0 1.8e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pCP017026_00004 - 2.8e-11 43.8 0.0 3.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP017026_00004 - 1.9e-10 40.9 0.0 3.6e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 pCP017026_00004 - 1.5e-07 30.9 0.1 3.2e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 pCP017026_00004 - 4e-06 27.2 0.2 1.1e-05 25.7 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 pCP017026_00004 - 7.9e-06 26.3 0.0 5.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 pCP017026_00004 - 9.5e-06 26.1 0.0 4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pCP017026_00004 - 1.5e-05 25.3 0.0 5.9e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pCP017026_00004 - 6.5e-05 23.0 0.0 9.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pCP017026_00004 - 0.00031 21.2 0.0 0.00041 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pCP017026_00004 - 0.001 18.4 0.2 0.0012 18.2 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 pCP017026_00004 - 0.0016 17.9 0.1 0.0038 16.7 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_19 PF13245.6 pCP017026_00004 - 0.0017 18.7 0.2 0.0035 17.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 pCP017026_00004 - 0.0019 17.9 0.4 0.004 16.9 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 pCP017026_00004 - 0.0023 17.7 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pCP017026_00004 - 0.0025 18.3 0.1 0.003 18.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 pCP017026_00004 - 0.0033 17.4 0.4 1 9.2 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 pCP017026_00004 - 0.0047 16.8 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase TIP49 PF06068.13 pCP017026_00004 - 0.0054 16.0 0.4 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 pCP017026_00004 - 0.0068 15.8 1.2 0.016 14.6 0.1 2.0 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 pCP017026_00004 - 0.01 15.2 1.0 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 pCP017026_00004 - 0.011 14.9 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 pCP017026_00004 - 0.016 14.9 0.1 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 pCP017026_00004 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 pCP017026_00004 - 0.018 15.0 0.6 0.036 14.0 0.2 1.7 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 pCP017026_00004 - 0.018 14.8 0.1 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 pCP017026_00004 - 0.02 14.5 0.3 0.071 12.7 0.1 2.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 pCP017026_00004 - 0.024 14.8 0.2 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.15 pCP017026_00004 - 0.033 14.1 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 pCP017026_00004 - 0.038 13.2 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ArsA_ATPase PF02374.15 pCP017026_00004 - 0.04 13.1 0.1 0.099 11.8 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase MKT1_N PF12247.8 pCP017026_00004 - 0.042 14.2 0.0 0.097 13.0 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Hydin_ADK PF17213.3 pCP017026_00004 - 0.043 14.1 1.2 0.054 13.8 0.2 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 pCP017026_00004 - 0.048 13.6 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 pCP017026_00004 - 0.051 13.4 1.5 0.1 12.4 1.5 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 pCP017026_00004 - 0.051 14.0 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 pCP017026_00004 - 0.055 13.2 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GvpD PF07088.11 pCP017026_00004 - 0.057 12.0 0.4 0.41 9.2 0.1 2.1 2 1 0 2 2 2 0 GvpD gas vesicle protein AAA_7 PF12775.7 pCP017026_00004 - 0.059 12.9 0.2 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 pCP017026_00004 - 0.079 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 pCP017026_00004 - 0.08 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 pCP017026_00004 - 0.086 12.5 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase1 PF18748.1 pCP017026_00004 - 0.1 12.1 0.1 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 IPT PF01745.16 pCP017026_00004 - 0.11 11.9 0.2 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 Isopentenyl transferase Ploopntkinase3 PF18751.1 pCP017026_00004 - 0.12 12.2 0.4 0.4 10.6 0.0 2.0 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 APH PF01636.23 pCP017026_00005 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP017026_00005 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP017026_00005 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP017026_00005 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP017026_00005 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP017026_00005 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP017026_00006 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pCP017026_00007 - 6.8e-11 42.6 0.0 8.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP017026_00007 - 0.014 14.6 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase CPT PF07931.12 pCP017026_00008 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 pCP017026_00008 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pCP017026_00008 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pCP017026_00008 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 pCP017026_00008 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3847 PF12958.7 pCP017026_00009 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 pCP017026_00009 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 pCP017026_00009 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 pCP017026_00009 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MobA_MobL PF03389.15 pCP017026_00010 - 3.7e-79 265.5 0.0 1.4e-78 263.6 0.0 1.9 2 0 0 2 2 2 1 MobA/MobL family Spectrin PF00435.21 pCP017026_00010 - 0.015 15.8 2.4 0.18 12.3 0.2 2.9 2 1 0 2 2 2 0 Spectrin repeat Prominin PF05478.11 pCP017026_00010 - 0.02 12.9 1.9 0.029 12.4 1.9 1.2 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.6 pCP017026_00010 - 0.021 15.2 2.0 0.059 13.8 0.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF2408 PF10303.9 pCP017026_00010 - 0.032 14.8 2.4 0.06 13.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 pCP017026_00010 - 0.065 13.5 2.3 6.6 7.1 0.3 3.5 4 0 0 4 4 4 0 Tup N-terminal Mod_r PF07200.13 pCP017026_00010 - 0.65 10.1 8.1 0.62 10.2 0.4 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SOAR PF16533.5 pCP017026_00010 - 1.2 9.1 5.4 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region DUF4407 PF14362.6 pCP017026_00010 - 5.1 6.4 8.4 53 3.0 8.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_25 PF13481.6 pCP017026_00011 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 pCP017026_00011 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 pCP017026_00011 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 pCP017026_00011 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 pCP017026_00011 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 pCP017026_00011 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 pCP017026_00011 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 pCP017026_00011 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 pCP017026_00011 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 pCP017026_00011 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 pCP017026_00011 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 pCP017026_00011 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 pCP017026_00011 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 pCP017026_00011 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 pCP017026_00011 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 pCP017026_00011 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 pCP017026_00011 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IMS_C PF11799.8 pCP017026_00012 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 pCP017026_00012 - 0.0002 21.5 0.0 0.00067 19.8 0.1 1.9 2 0 0 2 2 2 1 IMS family HHH motif Cob_adeno_trans PF01923.18 pCP017026_00015 - 0.014 15.6 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3825 PF12873.7 pCP017026_00016 - 4.2e-29 101.7 0.3 6.7e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF4795 PF16043.5 pCP017026_00017 - 0.026 14.1 0.1 0.043 13.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SGT1 PF07093.11 pCP017026_00018 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 pCP017026_00018 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 pCP017026_00018 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5309 PF17236.2 pCP017026_00019 - 3e-05 23.5 0.5 3.3e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5309) HicA_toxin PF07927.12 pCP017026_00020 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP017026_00021 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pCP017026_00021 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ParE_toxin PF05016.15 pCP017026_00023 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 pCP017026_00025 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF4131 PF13567.6 pCP017026_00026 - 0.00082 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 pCP017026_00026 - 0.014 15.3 3.1 0.018 15.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 pCP017026_00026 - 0.055 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2721 PF11026.8 pCP017026_00026 - 0.068 13.1 3.9 0.085 12.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2663 PF10864.8 pCP017026_00026 - 0.13 12.7 1.9 0.16 12.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) TraG_N PF07916.11 pCP017026_00027 - 3e-39 135.2 20.8 3e-39 135.2 20.8 3.2 3 1 0 4 4 4 1 TraG-like protein, N-terminal region Glyco_tranf_2_5 PF13712.6 pCP017026_00028 - 0.0018 18.0 4.5 0.0035 17.1 4.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family UvrA_DNA-bind PF17755.1 pCP017026_00029 - 0.0008 19.7 0.3 0.33 11.3 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 pCP017026_00030 - 0.003 17.9 0.2 2.1 8.7 0.1 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain Ank_2 PF12796.7 pCP017026_00033 - 1.4e-11 44.8 0.4 1.1e-06 29.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pCP017026_00033 - 5.4e-10 38.6 0.4 0.0094 16.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 pCP017026_00033 - 0.0016 19.0 0.1 0.32 11.6 0.0 3.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 pCP017026_00033 - 0.0035 17.7 0.0 17 6.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 pCP017026_00033 - 0.016 15.5 0.1 1.6 9.1 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pCP017026_00034 - 1.6e-07 31.5 0.0 1.6e-07 31.5 0.0 3.3 2 1 0 2 2 2 1 Restriction endonuclease fold toxin 7 Ank_2 PF12796.7 pCP017026_00035 - 1.6e-14 54.2 0.1 1.5e-08 35.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pCP017026_00035 - 6.1e-10 38.5 0.0 0.00093 19.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 pCP017026_00035 - 8.6e-06 26.2 0.0 0.0017 18.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 pCP017026_00035 - 3.4e-05 24.1 0.0 2.5 8.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pCP017026_00035 - 0.0018 18.6 0.3 0.13 12.6 0.0 3.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) APG17 PF04108.12 pCP017026_00035 - 0.017 14.2 0.7 0.024 13.8 0.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF2345 PF10106.9 pCP017026_00036 - 0.0046 16.8 2.2 0.016 15.1 2.2 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF3540 PF12059.8 pCP017026_00036 - 0.029 14.2 0.9 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Gp5_C PF06715.12 pCP017026_00036 - 0.094 12.9 0.1 0.094 12.9 0.1 4.7 3 1 2 5 5 5 0 Gp5 C-terminal repeat (3 copies) Bacteriocin_IIc PF10439.9 pCP017026_00037 - 0.0019 18.2 10.8 0.0019 18.2 10.8 1.8 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 pCP017026_00037 - 0.04 13.9 10.0 0.084 12.9 10.0 1.4 1 0 0 1 1 1 0 Glycine zipper DUF3482 PF11981.8 pCP017026_00037 - 0.1 12.0 1.3 0.21 11.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_YMGG PF13441.6 pCP017026_00037 - 0.17 11.6 8.3 0.36 10.6 8.3 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 pCP017026_00037 - 1.4 8.9 12.1 2.7 7.9 12.1 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1269 PF06897.12 pCP017026_00037 - 5.8 7.3 7.3 13 6.1 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Phage_GPD PF05954.11 pCP017026_00039 - 5.4e-18 65.3 0.0 8.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pCP017026_00039 - 0.11 12.1 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pCP017026_00040 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pCP017026_00041 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pCP017026_00042 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pCP017026_00042 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pCP017026_00042 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pCP017026_00043 - 1e-169 564.9 0.0 1.2e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pCP017026_00043 - 0.096 12.7 0.8 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pCP017026_00044 - 1.2e-51 174.6 3.8 1.3e-51 174.4 3.8 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pCP017026_00044 - 0.082 11.5 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pCP017026_00045 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pCP017026_00045 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pCP017026_00045 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 pCP017026_00045 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 pCP017026_00046 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pCP017026_00047 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pCP017026_00048 - 1.1e-34 120.0 0.0 1.2e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pCP017026_00049 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pCP017026_00050 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pCP017026_00050 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pCP017026_00050 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pCP017026_00050 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pCP017026_00050 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pCP017026_00050 - 0.0033 17.1 5.0 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pCP017026_00050 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pCP017026_00051 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pCP017026_00051 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pCP017026_00051 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain Y1_Tnp PF01797.16 pCP017026_00054 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pCP017026_00055 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pCP017026_00055 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pCP017026_00055 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pCP017026_00055 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pCP017026_00055 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pCP017026_00055 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pCP017026_00055 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pCP017026_00055 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pCP017026_00055 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 pCP017026_00056 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 pCP017026_00056 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 pCP017026_00057 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pCP017026_00058 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pCP017026_00058 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pCP017026_00058 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pCP017026_00058 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pCP017026_00058 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pCP017026_00058 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pCP017026_00058 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pCP017026_00058 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pCP017026_00058 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 pCP017026_00059 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 pCP017026_00059 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 pCP017026_00060 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pCP017026_00061 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pCP017026_00061 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pCP017026_00061 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pCP017026_00061 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pCP017026_00061 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pCP017026_00061 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pCP017026_00061 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pCP017026_00061 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pCP017026_00061 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3492 PF11997.8 pCP017026_00062 - 0.19 11.4 2.9 0.5 10.1 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CLZ PF16526.5 pCP017026_00062 - 0.99 9.8 4.8 11 6.5 0.2 3.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MeMO_Hyd_G PF02964.16 pCP017026_00063 - 0.078 13.0 0.7 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain Vta1 PF04652.16 pCP017026_00063 - 2.5 8.1 10.2 0.043 13.8 1.0 2.5 3 0 0 3 3 3 0 Vta1 like DUF2974 PF11187.8 pCP017026_00064 - 1.4e-06 28.0 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 pCP017026_00064 - 1e-05 25.4 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 pCP017026_00064 - 0.0019 17.7 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pCP017026_00064 - 0.0036 17.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF4450 PF14614.6 pCP017026_00064 - 0.016 14.8 0.2 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4450) UPF0227 PF05728.12 pCP017026_00064 - 0.028 14.4 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 pCP017026_00064 - 0.028 13.0 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 pCP017026_00064 - 0.049 14.2 0.0 0.069 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 pCP017026_00065 - 0.00072 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pCP017026_00065 - 0.044 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 pCP017026_00065 - 0.1 12.4 0.2 0.28 11.1 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Put_DNA-bind_N PF06971.13 pCP017026_00069 - 0.034 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus AAA_31 PF13614.6 pCP017026_00071 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017026_00071 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017026_00071 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pCP017026_00072 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_25 PF13481.6 pCP017026_00073 - 4.8e-15 55.7 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP017026_00073 - 0.0003 20.2 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP017026_00073 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP017026_00073 - 0.0091 15.4 0.4 0.074 12.4 0.0 2.5 3 1 0 3 3 3 1 KaiC AAA PF00004.29 pCP017026_00073 - 0.021 15.2 0.5 0.33 11.4 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ApoC-I PF04691.12 pCP017026_00073 - 0.16 11.9 3.3 5.1 7.1 0.0 3.9 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) CbiA PF01656.23 pCP017026_00073 - 0.24 11.4 2.2 1.1 9.4 2.2 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP017026_00073 - 0.7 9.5 5.5 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain DUF1947 PF09183.10 pCP017026_00073 - 0.73 10.2 6.3 1.7 9.0 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) HicA_toxin PF07927.12 pCP017026_00074 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP017026_00075 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCP017026_00077 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pCP017026_00077 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pCP017026_00077 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) nec1 PF10379.9 pCP017026_00078 - 0.036 13.6 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 pCP017026_00080 - 3.2e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pCP017026_00080 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP017026_00080 - 0.12 13.0 3.6 1.2 9.8 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Paz_1 PF18349.1 pCP017026_00080 - 0.12 12.3 0.9 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 PAZ domain TSC21 PF15217.6 pCP017026_00080 - 0.17 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 TSC21 family CdvA PF18822.1 pCP017026_00082 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pCP017026_00082 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pCP017026_00082 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pCP017026_00083 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP017026_00083 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP017026_00083 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP017026_00083 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP017026_00083 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 pCP017026_00084 - 3.7e-10 39.8 7.6 3.7e-10 39.8 7.6 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain Peptidase_C39 PF03412.15 pCP017026_00086 - 4.3e-18 65.4 0.0 5.6e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pCP017026_00086 - 9.8e-05 22.4 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 pCP017026_00086 - 0.046 14.3 0.0 0.099 13.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family GramPos_pilinBB PF16569.5 pCP017026_00089 - 0.016 16.0 3.9 0.19 12.6 1.9 2.3 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain DUF2768 PF10966.8 pCP017026_00089 - 0.052 14.0 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SNF2_N PF00176.23 pCP017026_00090 - 2.6e-16 59.3 1.7 4.4e-16 58.5 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP017026_00090 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP017026_00090 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP017026_00090 - 7.6e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP017026_00090 - 2.2e-05 24.9 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP017026_00091 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pCP017026_00092 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017026_00092 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017026_00092 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP017026_00092 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP017026_00092 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP017026_00093 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP017026_00093 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP017026_00094 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP017026_00094 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP017026_00094 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP017026_00094 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP017026_00094 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP017026_00095 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP017026_00095 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP017026_00095 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP017026_00095 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP017026_00095 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP017026_00095 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP017026_00095 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pCP017026_00096 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 pCP017026_00097 - 0.047 13.8 0.3 4.4 7.5 0.0 2.3 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pCP017026_00098 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP017026_00098 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain GTP_EFTU PF00009.27 pCP017026_00101 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP017026_00101 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP017026_00101 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP017026_00101 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP017026_00101 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP017026_00101 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP017026_00101 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP017026_00101 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP017026_00101 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pCP017026_00103 - 1.2e-05 25.3 2.3 3.2e-05 23.8 2.3 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP017026_00103 - 0.03 14.3 4.7 0.03 14.3 1.1 2.5 1 1 0 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 pCP017026_00105 - 9e-97 324.7 8.0 1.3e-96 324.2 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP017026_00105 - 9.7e-12 45.0 0.1 9.7e-12 45.0 0.1 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP017026_00105 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP017026_00105 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP017026_00105 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP017026_00105 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP017026_00105 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 pCP017026_00105 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 pCP017026_00105 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP017026_00105 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pCP017026_00105 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP017026_00105 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP017026_00105 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP017026_00105 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP017026_00105 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP017026_00105 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP017026_00105 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1461 PF07314.11 pCP017026_00106 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CdhD PF03599.16 pCP017026_00107 - 0.004 15.9 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 pCP017026_00107 - 0.056 13.2 0.7 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP017026_00108 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pCP017026_00108 - 1.3 8.8 9.6 3.3 7.4 8.5 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT20 PF14931.6 pCP017026_00108 - 4.9 7.3 10.2 1.5 9.0 0.5 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 TrbM PF07424.11 pCP017026_00109 - 3.9e-38 130.8 2.1 5e-38 130.5 2.1 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 pCP017026_00109 - 0.17 10.9 0.1 1 8.4 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Cag12 PF13117.6 pCP017026_00110 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP017026_00110 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) T4SS-DNA_transf PF02534.14 pCP017026_00111 - 6.8e-104 348.3 0.1 9.2e-104 347.8 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP017026_00111 - 3.1e-24 85.3 0.0 6.1e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP017026_00111 - 2.6e-15 56.3 0.0 5.1e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 pCP017026_00112 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP017026_00112 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP017026_00112 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP017026_00112 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP017026_00112 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP017026_00112 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pCP017026_00112 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pCP017026_00112 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP017026_00112 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP017026_00112 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP017026_00112 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP017026_00112 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pCP017026_00112 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 pCP017026_00112 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 pCP017026_00112 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 pCP017026_00112 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 pCP017026_00112 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 pCP017026_00112 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pCP017026_00112 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 pCP017026_00112 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pCP017026_00112 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pCP017026_00112 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP017026_00112 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP017026_00112 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP017026_00112 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP017026_00112 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP017026_00112 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP017026_00112 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP017026_00112 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP017026_00112 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP017026_00112 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP017026_00113 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP017026_00113 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP017026_00114 - 4.5e-56 189.9 2.1 7.1e-56 189.3 2.1 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pCP017026_00114 - 0.021 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 TraE protein VirB8 PF04335.13 pCP017026_00115 - 1.6e-52 178.4 0.4 1.8e-52 178.3 0.4 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP017026_00115 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pCP017026_00116 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pCP017026_00116 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pCP017026_00116 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pCP017026_00117 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP017026_00117 - 0.065 13.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pCP017026_00117 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) T4SS PF07996.11 pCP017026_00118 - 1.8e-28 100.3 13.3 2.5e-28 99.9 13.3 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP017026_00118 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pCP017026_00118 - 0.017 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pCP017026_00118 - 0.5 11.1 11.4 0.41 11.3 4.5 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 pCP017026_00119 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP017026_00119 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP017026_00119 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP017026_00119 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP017026_00120 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 pCP017026_00121 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 pCP017026_00122 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pCP017026_00122 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pCP017026_00122 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 pCP017026_00123 - 6.9e-51 173.3 0.4 1.6e-50 172.1 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP017026_00123 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 pCP017026_00124 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP017026_00124 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP017026_00126 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 CRISPR associated protein Cas2 Resolvase PF00239.21 pCP017026_00127 - 1.4e-33 116.0 0.8 2e-33 115.6 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_Mga PF08280.11 pCP017026_00127 - 0.03 14.4 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_38 PF13936.6 pCP017026_00127 - 0.042 13.6 0.8 4.9 7.0 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain RepL PF05732.11 pCP017026_00128 - 5.2e-17 61.8 0.0 6e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_5 PF01022.20 pCP017026_00128 - 6.3e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 pCP017026_00128 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF4423 PF14394.6 pCP017026_00128 - 0.00096 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_11 PF08279.12 pCP017026_00128 - 0.0036 17.2 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 pCP017026_00128 - 0.0037 17.2 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 pCP017026_00128 - 0.0046 16.8 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 pCP017026_00128 - 0.0048 16.9 0.0 0.0068 16.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 pCP017026_00128 - 0.023 15.0 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 pCP017026_00128 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_rep_org_N PF09681.10 pCP017026_00128 - 0.038 13.9 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) CRISPR_Cas2 PF09827.9 pCP017026_00129 - 1.6e-11 44.2 0.1 2e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas2 Citrate_ly_lig PF08218.11 pCP017026_00129 - 0.093 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain TIR_2 PF13676.6 pCP017026_00130 - 2.1e-05 25.1 0.1 8.4e-05 23.2 0.1 2.1 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 pCP017026_00130 - 0.012 16.0 1.2 0.012 16.0 1.2 3.1 3 1 0 3 3 3 0 MTH538 TIR-like domain (DUF1863) T_Ag_DNA_bind PF02217.16 pCP017026_00130 - 2.7 8.6 7.4 0.19 12.3 1.8 2.0 2 1 0 2 2 2 0 Origin of replication binding protein DUF1899 PF08953.11 pCP017026_00131 - 0.095 12.6 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) XhlA PF10779.9 pCP017026_00131 - 0.12 12.6 1.7 0.25 11.6 1.7 1.6 1 0 0 1 1 1 0 Haemolysin XhlA AAA_25 PF13481.6 pCP017026_00132 - 5.2e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP017026_00132 - 0.00056 19.3 0.0 0.0044 16.4 0.0 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP017026_00132 - 0.0015 18.3 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP017026_00132 - 0.0044 16.8 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP017026_00132 - 0.0061 15.9 0.1 0.046 13.1 0.0 2.6 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP017026_00132 - 0.092 13.2 0.2 1.4 9.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP017026_00132 - 0.2 11.7 1.5 0.69 10.0 1.4 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicA_toxin PF07927.12 pCP017026_00133 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP017026_00134 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system TRADD_N PF09034.10 pCP017026_00135 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain Peptidase_M4_C PF02868.15 pCP017026_00135 - 0.18 11.7 1.3 0.37 10.6 0.1 2.0 2 1 1 3 3 3 0 Thermolysin metallopeptidase, alpha-helical domain AAA_31 PF13614.6 pCP017026_00136 - 6.3e-05 23.0 0.6 0.0013 18.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017026_00136 - 0.0021 18.1 0.8 0.017 15.2 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017026_00136 - 0.02 14.4 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pCP017026_00137 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG NYN PF01936.18 pCP017026_00139 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pCP017026_00139 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pCP017026_00139 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain DUF2400 PF09674.10 pCP017026_00140 - 0.26 11.2 4.0 0.56 10.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP017026_00141 - 3.2e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pCP017026_00141 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP017026_00141 - 0.12 13.0 3.6 1.2 9.8 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Paz_1 PF18349.1 pCP017026_00141 - 0.12 12.3 0.9 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 PAZ domain TSC21 PF15217.6 pCP017026_00141 - 0.17 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 TSC21 family CitMHS PF03600.16 pCP017026_00147 - 0.014 14.6 0.6 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 pCP017026_00147 - 0.27 10.9 6.3 0.4 10.4 6.3 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 pCP017026_00147 - 0.46 9.9 7.7 0.75 9.2 7.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DUF3810 PF12725.7 pCP017026_00147 - 0.68 9.2 12.4 0.82 8.9 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DHHC PF01529.20 pCP017026_00147 - 8.2 6.5 12.2 15 5.7 12.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase CitMHS PF03600.16 pCP017026_00149 - 0.014 14.6 0.6 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 pCP017026_00149 - 0.27 10.9 6.3 0.4 10.4 6.3 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 pCP017026_00149 - 0.46 9.9 7.7 0.75 9.2 7.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DUF3810 PF12725.7 pCP017026_00149 - 0.68 9.2 12.4 0.82 8.9 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DHHC PF01529.20 pCP017026_00149 - 8.2 6.5 12.2 15 5.7 12.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3344 PF11824.8 pCP017026_00151 - 0.087 12.4 0.5 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) DUF5013 PF16405.5 pCP017026_00153 - 0.0095 16.2 0.0 0.08 13.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5013) AMPK1_CBM PF16561.5 pCP017026_00153 - 0.088 13.0 0.0 0.41 10.9 0.0 2.1 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Ribophorin_II PF05817.14 pCP017026_00154 - 1.4 7.4 7.7 2 6.9 7.7 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II SseC PF04888.12 pCP017026_00157 - 0.004 16.8 0.2 0.014 15.1 0.2 1.9 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 pCP017026_00157 - 0.014 14.8 0.8 0.036 13.4 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pCP017026_00157 - 0.036 14.0 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 pCP017026_00157 - 0.062 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Ank_3 PF13606.6 pCP017026_00159 - 3.6e-09 36.1 0.2 0.013 16.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 pCP017026_00159 - 4.6e-08 33.5 0.0 3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 pCP017026_00159 - 0.00033 21.0 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pCP017026_00159 - 0.0019 18.5 0.3 0.03 14.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 pCP017026_00159 - 0.0027 18.3 0.1 0.17 12.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pCP017026_00160 - 1.6e-07 31.5 0.0 1.6e-07 31.5 0.0 3.3 2 1 0 2 2 2 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 pCP017026_00160 - 8.1 6.2 10.9 1.6 8.5 0.6 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF4637 PF15470.6 pCP017026_00160 - 9.9 5.9 8.5 0.49 10.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Ank_3 PF13606.6 pCP017026_00161 - 3.6e-09 36.1 0.2 0.013 16.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 pCP017026_00161 - 4.6e-08 33.5 0.0 3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 pCP017026_00161 - 0.00033 21.0 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pCP017026_00161 - 0.0019 18.5 0.3 0.03 14.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 pCP017026_00161 - 0.0027 18.3 0.1 0.17 12.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ntox24 PF15529.6 pCP017026_00164 - 0.0021 18.3 0.8 0.0039 17.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial toxin 24 CobN-Mg_chel PF02514.16 pCP017026_00165 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase LPD7 PF18821.1 pCP017026_00166 - 0.0092 16.1 0.4 3 8.0 0.1 2.3 1 1 1 2 2 2 2 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 pCP017026_00166 - 0.13 12.8 10.6 0.13 12.8 3.6 3.1 1 1 2 3 3 3 0 Immunity protein 59 ABC2_membrane_3 PF12698.7 pCP017026_00166 - 0.29 10.2 0.8 0.32 10.1 0.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AHH PF14412.6 pCP017026_00167 - 6.2e-16 58.5 1.7 1.2e-15 57.6 1.7 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF4299 PF14132.6 pCP017026_00169 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pCP017026_00169 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pCP017026_00169 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region Phage_GPD PF05954.11 pCP017026_00171 - 5.5e-18 65.3 0.0 8.6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pCP017026_00171 - 0.11 12.1 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family DivIC PF04977.15 pCP017026_00173 - 0.0014 18.3 0.2 0.0014 18.3 0.2 4.2 5 0 0 5 5 5 1 Septum formation initiator DZR PF12773.7 pCP017026_00174 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 pCP017026_00174 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 pCP017026_00174 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rapsyn_N PF10579.9 pCP017026_00175 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SprT-like PF10263.9 pCP017026_00177 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 pCP017026_00177 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain Phage_integrase PF00589.22 pCP017026_00180 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pCP017026_00180 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pCP017026_00180 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 pCP017026_00180 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 pCP017026_00180 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 pCP017026_00180 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlaC_arch PF05377.11 pCP017026_00181 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) WGR PF05406.15 pCP017026_00182 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pCP017026_00182 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like YafQ_toxin PF15738.5 pCP017026_00186 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pCP017026_00186 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 pCP017026_00186 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 pCP017026_00186 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system CCDC-167 PF15188.6 pCP017026_00191 - 0.002 18.4 0.4 0.0033 17.7 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 pCP017026_00191 - 0.015 15.4 3.5 0.04 14.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) HSBP1 PF06825.12 pCP017026_00191 - 0.033 14.0 0.1 2.2 8.2 0.0 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Streptin-Immun PF11083.8 pCP017026_00191 - 0.052 14.0 0.6 0.2 12.1 0.1 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4164 PF13747.6 pCP017026_00191 - 0.1 12.9 0.4 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Trimer_CC PF08954.11 pCP017026_00191 - 0.14 11.7 0.1 9.8 5.8 0.0 3.0 1 1 1 2 2 2 0 Trimerisation motif Sigma_reg_N PF13800.6 pCP017026_00192 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5601 PF18151.1 pCP017026_00193 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 pCP017026_00193 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) HTH_3 PF01381.22 pCP017026_00195 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pCP017026_00195 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pCP017026_00195 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 pCP017026_00195 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP017026_00195 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pCP017026_00195 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pCP017026_00195 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pCP017026_00195 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pCP017026_00195 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pCP017026_00195 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pCP017026_00195 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pCP017026_00195 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pCP017026_00195 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 pCP017026_00195 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 pCP017026_00195 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 pCP017026_00195 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 pCP017026_00195 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 pCP017026_00195 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pCP017026_00195 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pCP017026_00195 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain LysE PF01810.18 pCP017230_00001 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP017230_00001 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP017230_00001 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP017230_00001 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP017230_00001 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP017230_00001 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP017230_00001 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP017230_00001 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP017230_00001 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP017230_00002 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP017230_00002 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP017230_00002 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP017230_00002 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP017230_00002 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP017230_00003 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP017230_00003 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP017230_00004 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017230_00004 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017230_00004 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP017230_00004 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP017230_00004 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP017230_00005 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP017230_00006 - 3.5e-16 58.9 1.1 7.4e-16 57.8 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP017230_00006 - 4e-08 33.4 8.0 4e-08 33.4 8.0 4.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP017230_00006 - 1.2e-06 28.8 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP017230_00006 - 5.8e-06 26.2 1.2 0.0013 18.5 0.2 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP017230_00006 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pCP017230_00007 - 0.0008 19.8 0.1 0.002 18.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2768 PF10966.8 pCP017230_00007 - 0.011 16.1 0.9 0.026 15.0 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) Acetyltransf_1 PF00583.25 pCP017230_00007 - 0.021 15.1 0.1 0.051 13.8 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GramPos_pilinBB PF16569.5 pCP017230_00007 - 0.22 12.3 4.3 0.17 12.7 1.7 1.9 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain CooC_C PF15976.5 pCP017230_00009 - 0.12 12.4 0.4 0.62 10.2 0.2 2.1 2 0 0 2 2 2 0 CS1-pili formation C-terminal EVI2A PF05399.11 pCP017230_00009 - 2.8 7.5 10.5 6.1 6.4 10.5 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Peptidase_C39 PF03412.15 pCP017230_00011 - 9e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pCP017230_00011 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 pCP017230_00011 - 0.086 13.4 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family Relaxase PF03432.14 pCP017230_00013 - 1.6e-10 41.1 7.7 1.6e-10 41.1 7.7 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP017230_00014 - 4.6e-05 23.3 7.5 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP017230_00014 - 0.032 14.4 2.3 0.041 14.0 1.6 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP017230_00014 - 0.1 12.7 5.3 1.5 8.9 0.3 2.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP017230_00014 - 0.48 10.7 7.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pCP017230_00015 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP017230_00015 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP017230_00015 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pCP017230_00018 - 2.3e-08 34.3 0.2 6.4e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP017230_00018 - 0.024 14.9 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein 5_3_exonuc PF01367.20 pCP017230_00018 - 0.36 11.5 2.6 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP017230_00019 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP017230_00019 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain DUF1451 PF07295.11 pCP017230_00020 - 0.00056 20.0 0.0 0.00063 19.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain DUF4145 PF13643.6 pCP017230_00021 - 2.5e-16 59.6 5.0 1.4e-15 57.1 0.1 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4145) Glyco_hydro_16 PF00722.21 pCP017230_00024 - 0.081 12.4 0.4 0.081 12.4 0.4 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 HicB_lk_antitox PF15919.5 pCP017230_00025 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP017230_00026 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP017230_00027 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP017230_00027 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP017230_00027 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP017230_00027 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP017230_00027 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP017230_00027 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pCP017230_00028 - 0.012 15.5 0.4 0.02 14.7 0.4 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pCP017230_00030 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP017230_00030 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP017230_00030 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP017230_00030 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP017230_00031 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP017230_00031 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP017230_00033 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP017230_00033 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP017230_00034 - 7.4e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP017230_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP017230_00034 - 3.9e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP017230_00034 - 0.033 14.3 5.2 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pCP017230_00035 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP017230_00035 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP017230_00035 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP017230_00035 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP017230_00035 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 pCP017230_00036 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 pCP017230_00037 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP017230_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP017230_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP017230_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP017230_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP017230_00039 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP017230_00039 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP017230_00039 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP017230_00039 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP017230_00039 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 pCP017230_00039 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 pCP017230_00039 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pCP017230_00039 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pCP017230_00040 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP017230_00040 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP017230_00040 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP017230_00041 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP017230_00041 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP017230_00042 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP017230_00042 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP017230_00043 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP017230_00043 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP017230_00044 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP017230_00044 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP017230_00045 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP017230_00045 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP017230_00045 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP017230_00045 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP017230_00045 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP017230_00045 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP017230_00045 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP017230_00045 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP017230_00045 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP017230_00045 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP017230_00045 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP017230_00045 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP017230_00045 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP017230_00045 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP017230_00045 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP017230_00045 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP017230_00045 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP017230_00045 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP017230_00045 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP017230_00045 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP017230_00045 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP017230_00045 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP017230_00045 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP017230_00045 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP017230_00045 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP017230_00045 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP017230_00045 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP017230_00045 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP017230_00045 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP017230_00045 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP017230_00045 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP017230_00046 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP017230_00046 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP017230_00046 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP017230_00046 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP017230_00047 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP017230_00047 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP017230_00047 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP017230_00047 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP017230_00048 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP017230_00049 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP017230_00049 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP017230_00049 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP017230_00051 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP017230_00052 - 1.4e-97 327.4 8.2 1.9e-97 326.9 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP017230_00052 - 4.7e-12 46.0 3.1 5.4e-12 45.8 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP017230_00052 - 0.05 13.4 2.1 0.14 12.0 2.1 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP017230_00052 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon EF-hand_8 PF13833.6 pCP017230_00052 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP017230_00052 - 0.34 11.1 3.3 0.78 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pCP017230_00053 - 4.7e-05 23.3 2.2 0.00012 22.0 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP017230_00053 - 0.025 14.5 4.1 0.18 11.7 4.1 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP017230_00055 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP017230_00055 - 3.4e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP017230_00055 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP017230_00055 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP017230_00055 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP017230_00055 - 0.0015 18.9 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP017230_00055 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP017230_00055 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP017230_00055 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pCP017230_00055 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Rrp15p PF07890.12 pCP017230_00057 - 0.41 11.0 7.3 0.42 10.9 7.3 1.1 1 0 0 1 1 1 0 Rrp15p Oxysterol_BP PF01237.18 pCP017230_00057 - 0.82 8.4 6.8 0.84 8.4 6.8 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Asp4 PF16996.5 pCP017230_00057 - 1.1 9.1 4.3 0.9 9.4 2.6 1.7 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 Casc1_N PF15927.5 pCP017230_00057 - 1.8 8.2 14.1 2.1 8.0 14.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Herpes_UL56 PF04534.12 pCP017230_00057 - 2.6 7.5 9.7 3.2 7.2 9.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Radial_spoke_3 PF06098.11 pCP017230_00057 - 5.5 6.2 13.0 6 6.1 13.0 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 CtsR_C PF17727.1 pCP017230_00060 - 0.019 15.1 0.2 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain AAA_31 PF13614.6 pCP017417_00001 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017417_00001 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017417_00001 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RseC_MucC PF04246.12 pCP017417_00002 - 9.1 6.3 6.3 2.4 8.1 3.1 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NnrS PF05940.12 pCP017417_00003 - 0.023 14.1 9.9 0.028 13.8 9.9 1.0 1 0 0 1 1 1 0 NnrS protein DUF2070 PF09843.9 pCP017417_00003 - 0.054 11.8 13.4 0.063 11.6 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 pCP017417_00003 - 0.15 12.4 19.9 0.53 10.7 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 pCP017417_00003 - 0.51 9.7 27.0 0.49 9.7 7.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF5385 PF17359.2 pCP017417_00003 - 0.52 9.8 9.3 0.099 12.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NVEALA PF14055.6 pCP017417_00003 - 4.1 7.4 6.4 4.2 7.4 0.2 2.9 1 1 2 3 3 3 0 NVEALA protein TssN PF17555.2 pCP017417_00003 - 4.7 6.5 20.7 5.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2663 PF10864.8 pCP017417_00003 - 6.7 7.1 10.9 36 4.8 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Lipase_3 PF01764.25 pCP017417_00004 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pCP017417_00004 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 pCP017417_00004 - 2.7e-05 24.0 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 pCP017417_00004 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 pCP017417_00004 - 0.00045 19.9 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pCP017417_00004 - 0.0017 19.0 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pCP017417_00004 - 0.0021 18.1 0.9 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 pCP017417_00004 - 0.016 14.8 0.1 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF1257 PF06868.11 pCP017417_00004 - 0.24 11.7 2.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) SBDS PF01172.18 pCP017417_00004 - 0.79 9.8 5.3 0.83 9.8 1.4 3.2 2 2 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein SseC PF04888.12 pCP017417_00007 - 0.0012 18.5 0.2 0.0032 17.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family APOBEC_C PF05240.14 pCP017417_00007 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ThrE PF06738.12 pCP017417_00007 - 0.019 14.3 0.8 0.051 12.9 0.8 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pCP017417_00007 - 0.033 14.1 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone PTS_EIIC_2 PF13303.6 pCP017417_00007 - 0.037 13.1 1.0 0.064 12.3 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC TPR_11 PF13414.6 pCP017417_00007 - 0.064 12.9 0.3 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 TPR repeat Glyco_tranf_2_5 PF13712.6 pCP017417_00009 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 pCP017417_00010 - 3.3e-42 144.9 22.9 3.3e-42 144.9 22.9 2.2 2 1 0 2 2 2 1 TraG-like protein, N-terminal region CHMI PF02962.15 pCP017417_00010 - 0.017 15.5 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 pCP017417_00013 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pCP017417_00013 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 pCP017417_00013 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 pCP017417_00013 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 pCP017417_00015 - 8.6e-09 35.6 0.3 0.00036 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pCP017417_00015 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 pCP017417_00016 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 pCP017417_00018 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 pCP017417_00018 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein DHHA1 PF02272.19 pCP017417_00019 - 0.18 12.2 1.6 0.37 11.2 1.6 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 pCP017417_00020 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 pCP017417_00021 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pCP017417_00021 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pCP017417_00021 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 pCP017417_00023 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 pCP017417_00023 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 pCP017417_00025 - 1.5e-25 89.9 0.2 4e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family CooC_C PF15976.5 pCP017417_00027 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 pCP017417_00027 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 pCP017417_00028 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pCP017417_00028 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pCP017417_00028 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pCP017417_00028 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 pCP017417_00028 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 pCP017417_00028 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pCP017417_00028 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pCP017417_00028 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pCP017417_00028 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pCP017417_00028 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pCP017417_00028 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pCP017417_00028 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pCP017417_00028 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 pCP017417_00028 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 pCP017417_00028 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 pCP017417_00028 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 pCP017417_00028 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 pCP017417_00028 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pCP017417_00028 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pCP017417_00028 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 pCP017417_00030 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 pCP017417_00030 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HSBP1 PF06825.12 pCP017417_00033 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 pCP017417_00033 - 0.026 14.9 0.3 0.039 14.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 pCP017417_00033 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 pCP017417_00033 - 0.11 12.8 0.3 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_NinH PF06322.11 pCP017417_00034 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein WGR PF05406.15 pCP017417_00038 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pCP017417_00038 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 pCP017417_00039 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 pCP017417_00040 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pCP017417_00040 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pCP017417_00040 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pCP017417_00040 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 pCP017417_00040 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 pCP017417_00040 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 pCP017417_00040 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Prok-TraM PF09228.10 pCP017417_00042 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 pCP017417_00042 - 3 8.1 11.1 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 pCP017417_00043 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 pCP017417_00044 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pCP017417_00044 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pCP017417_00044 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 pCP017417_00046 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pCP017417_00046 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 pCP017417_00048 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 pCP017417_00050 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 pCP017417_00050 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 pCP017417_00050 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 pCP017417_00052 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 pCP017417_00053 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 pCP017417_00053 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 pCP017417_00053 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 pCP017417_00053 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myc-LZ PF02344.15 pCP017417_00054 - 0.045 13.9 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Myc leucine zipper domain Importin_rep PF18773.1 pCP017417_00055 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 pCP017417_00055 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 pCP017417_00055 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 pCP017417_00056 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pCP017417_00056 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pCP017417_00057 - 3.5e-47 161.1 0.0 3.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pCP017417_00058 - 1.6e-110 370.4 0.0 1.8e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pCP017417_00059 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pCP017417_00059 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pCP017417_00059 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pCP017417_00060 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pCP017417_00060 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pCP017417_00061 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pCP017417_00061 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pCP017417_00062 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pCP017417_00062 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pCP017417_00062 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 pCP017417_00062 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 pCP017417_00063 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pCP017417_00064 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pCP017417_00065 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pCP017417_00066 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pCP017417_00067 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pCP017417_00067 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pCP017417_00067 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pCP017417_00067 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pCP017417_00067 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pCP017417_00067 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pCP017417_00067 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pCP017417_00068 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pCP017417_00068 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pCP017417_00068 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3870 PF12986.7 pCP017417_00069 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) DUF2459 PF09601.10 pCP017417_00072 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) BLOC1_2 PF10046.9 pCP017417_00072 - 0.1 12.9 2.0 0.25 11.7 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_DNA-bind_N PF06971.13 pCP017417_00073 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Toprim_3 PF13362.6 pCP017417_00074 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP017417_00074 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP017417_00074 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pCP017417_00074 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold NYN PF01936.18 pCP017417_00076 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pCP017417_00076 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pCP017417_00076 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain AAA_31 PF13614.6 pCP017418_00001 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017418_00001 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017418_00001 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pCP017418_00002 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP017418_00003 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP017418_00003 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP017418_00003 - 9.4e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP017418_00003 - 1.3e-05 25.0 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP017418_00003 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase HTH_19 PF12844.7 pCP017418_00004 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pCP017418_00004 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pCP017418_00004 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pCP017418_00004 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pCP017418_00004 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP017418_00004 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pCP017418_00004 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 pCP017418_00004 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 pCP017418_00004 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 pCP017418_00004 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 pCP017418_00004 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pCP017418_00004 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 pCP017418_00004 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 pCP017418_00004 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Relaxase PF03432.14 pCP017418_00005 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP017418_00006 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP017418_00006 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP017418_00006 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP017418_00006 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pCP017418_00006 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain CdvA PF18822.1 pCP017418_00007 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pCP017418_00007 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pCP017418_00007 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pCP017418_00009 - 0.00054 20.3 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF4223 PF13978.6 pCP017418_00010 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pCP017418_00010 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 pCP017418_00011 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pCP017418_00011 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pCP017418_00011 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP017418_00013 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP017418_00014 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP017418_00015 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP017418_00015 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP017418_00015 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP017418_00015 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP017418_00015 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP017418_00015 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP017418_00015 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pCP017418_00016 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP017418_00016 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP017418_00016 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pCP017418_00017 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pCP017418_00019 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP017418_00019 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP017418_00020 - 4e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP017418_00020 - 3.7e-21 75.1 1.1 6.4e-21 74.4 1.1 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP017418_00020 - 4.4e-07 29.2 0.5 1e-06 28.0 0.5 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP017418_00020 - 0.0092 16.1 2.9 1.7 8.7 0.0 3.8 4 1 1 5 5 5 2 Helicase HerA, central domain Phage_pRha PF09669.10 pCP017418_00021 - 6.6e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP017418_00021 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 pCP017418_00021 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) DUF3251 PF11622.8 pCP017418_00022 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP017418_00022 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP017418_00022 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP017418_00022 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP017418_00022 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP017418_00022 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP017418_00023 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP017418_00024 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP017418_00024 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP017418_00024 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP017418_00024 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP017418_00025 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP017418_00025 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP017418_00025 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP017418_00025 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP017418_00025 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCP017418_00025 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pCP017418_00025 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pCP017418_00025 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pCP017418_00026 - 2.7e-31 109.0 32.0 2.7e-31 109.0 32.0 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein DUF3176 PF11374.8 pCP017418_00026 - 0.088 13.0 0.5 0.088 13.0 0.5 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF3176) T_cell_tran_alt PF15128.6 pCP017418_00026 - 0.18 11.6 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP017418_00026 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP017418_00027 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP017418_00027 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP017418_00028 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP017418_00028 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP017418_00029 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP017418_00029 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP017418_00030 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP017418_00030 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP017418_00031 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP017418_00031 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP017418_00031 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP017418_00031 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP017418_00031 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP017418_00031 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP017418_00031 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP017418_00031 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP017418_00031 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP017418_00031 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP017418_00031 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP017418_00031 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP017418_00031 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP017418_00031 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP017418_00031 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP017418_00031 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP017418_00031 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP017418_00031 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP017418_00031 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP017418_00031 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP017418_00031 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP017418_00031 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP017418_00031 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP017418_00031 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP017418_00031 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP017418_00031 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP017418_00031 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP017418_00031 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP017418_00031 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP017418_00031 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP017418_00031 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP017418_00032 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP017418_00032 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP017418_00032 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP017418_00032 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP017418_00033 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP017418_00033 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP017418_00033 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP017418_00033 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP017418_00034 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP017418_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP017418_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP017418_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP017418_00037 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP017418_00038 - 1e-96 324.5 8.2 1.4e-96 324.0 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP017418_00038 - 1.5e-12 47.6 0.4 9.4e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP017418_00038 - 1.5e-06 27.9 5.0 3.8e-06 26.6 5.0 1.8 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 pCP017418_00038 - 0.079 12.8 0.0 0.28 11.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair zinc_ribbon_9 PF14369.6 pCP017418_00038 - 0.22 11.8 0.7 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 zinc-ribbon HTH_34 PF13601.6 pCP017418_00038 - 0.4 10.9 3.3 0.79 9.9 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pCP017418_00039 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP017418_00039 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain GTP_EFTU PF00009.27 pCP017418_00041 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP017418_00041 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP017418_00041 - 9.3e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP017418_00041 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP017418_00041 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP017418_00041 - 0.00031 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP017418_00041 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP017418_00041 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP017418_00041 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF5442 PF17514.2 pCP017418_00042 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pCP017418_00044 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP017418_00044 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pCP017418_00045 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP017418_00045 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP017418_00046 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pCP017418_00047 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP017418_00047 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP017418_00047 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP017418_00047 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP017418_00047 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP017418_00047 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP017418_00047 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pCP017418_00048 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP017418_00048 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP017418_00048 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP017418_00048 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP017418_00048 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP017418_00049 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP017418_00049 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Toprim_3 PF13362.6 pCP017854_00001 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP017854_00001 - 0.016 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP017854_00001 - 0.017 15.2 6.4 1.2 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 DUF4223 PF13978.6 pCP017854_00002 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP017854_00002 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 pCP017854_00003 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 pCP017854_00004 - 5.1e-29 101.4 6.3 9.5e-29 100.6 6.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pCP017854_00004 - 2e-26 92.8 0.9 3.2e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pCP017854_00004 - 4e-06 25.9 0.8 5.9e-06 25.3 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 pCP017854_00004 - 0.0032 17.5 0.9 0.0087 16.1 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) RIO1 PF01163.22 pCP017854_00004 - 0.0073 15.9 2.5 0.0073 15.9 2.5 1.6 2 0 0 2 2 2 1 RIO1 family ORC6 PF05460.13 pCP017854_00004 - 0.0086 15.4 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pectate_lyase_3 PF12708.7 pCP017854_00004 - 0.068 13.0 0.4 0.14 12.0 0.4 1.4 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pex19 PF04614.12 pCP017854_00004 - 3.6 7.3 5.4 7.5 6.2 5.4 1.5 1 0 0 1 1 1 0 Pex19 protein family HicB_lk_antitox PF15919.5 pCP017854_00006 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP017854_00006 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 pCP017854_00007 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP017854_00007 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP017854_00007 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP017854_00007 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP017854_00007 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP017854_00007 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pCP017854_00008 - 0.013 15.3 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pCP017854_00010 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP017854_00010 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP017854_00010 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP017854_00010 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP017854_00011 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP017854_00011 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP017854_00013 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP017854_00013 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP017854_00014 - 1.3e-51 175.6 0.7 3e-51 174.5 0.7 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP017854_00014 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP017854_00014 - 0.045 13.2 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP017854_00015 - 1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP017854_00015 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 pCP017854_00016 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP017854_00016 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP017854_00016 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP017854_00016 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP017854_00016 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP017854_00016 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP017854_00017 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP017854_00018 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP017854_00018 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP017854_00018 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP017854_00018 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP017854_00019 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP017854_00019 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP017854_00019 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP017854_00019 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pCP017854_00019 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pCP017854_00019 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 pCP017854_00020 - 4.7e-29 101.7 31.2 4.7e-29 101.7 31.2 1.8 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP017854_00020 - 0.22 11.3 1.3 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP017854_00020 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP017854_00021 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP017854_00021 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP017854_00022 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP017854_00022 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP017854_00023 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP017854_00023 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP017854_00024 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP017854_00024 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP017854_00025 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP017854_00025 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP017854_00025 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP017854_00025 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP017854_00025 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP017854_00025 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP017854_00025 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP017854_00025 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP017854_00025 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP017854_00025 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP017854_00025 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP017854_00025 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP017854_00025 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP017854_00025 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP017854_00025 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP017854_00025 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP017854_00025 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP017854_00025 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP017854_00025 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP017854_00025 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP017854_00025 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP017854_00025 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP017854_00025 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP017854_00025 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP017854_00025 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP017854_00025 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP017854_00025 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP017854_00025 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP017854_00025 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP017854_00025 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP017854_00025 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP017854_00026 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP017854_00026 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP017854_00026 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP017854_00026 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP017854_00027 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP017854_00027 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP017854_00027 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP017854_00027 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP017854_00028 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP017854_00029 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP017854_00029 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP017854_00029 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP017854_00031 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP017854_00032 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP017854_00032 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 pCP017854_00032 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 pCP017854_00032 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 pCP017854_00032 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP017854_00032 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pCP017854_00033 - 5.1e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP017854_00033 - 0.02 14.8 3.9 0.17 11.9 3.9 2.6 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP017854_00035 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP017854_00035 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP017854_00035 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP017854_00035 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP017854_00035 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP017854_00035 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP017854_00035 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP017854_00035 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP017854_00035 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Sgf11 PF08209.11 pCP017854_00036 - 0.11 12.1 0.8 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) CtsR_C PF17727.1 pCP017854_00037 - 0.031 14.4 0.2 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Lip_prot_lig_C PF10437.9 pCP017854_00037 - 0.049 13.6 2.7 0.17 11.9 2.2 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus LysE PF01810.18 pCP017854_00038 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP017854_00038 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP017854_00038 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP017854_00038 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP017854_00038 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP017854_00038 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP017854_00038 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP017854_00038 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP017854_00038 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP017854_00039 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP017854_00039 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP017854_00039 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP017854_00039 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP017854_00039 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP017854_00040 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP017854_00040 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP017854_00041 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017854_00041 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017854_00041 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP017854_00041 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP017854_00041 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP017854_00042 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP017854_00043 - 2.2e-16 59.5 2.2 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP017854_00043 - 5e-08 33.1 8.3 5e-08 33.1 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP017854_00043 - 9.5e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP017854_00043 - 1.1e-05 25.3 2.2 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP017854_00043 - 3.1e-05 24.4 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase DUF3800 PF12686.7 pCP017854_00044 - 6e-06 26.9 8.9 6e-06 26.9 8.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3800) CM_2 PF01817.21 pCP017854_00044 - 0.032 14.6 0.2 0.082 13.3 0.2 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Myb_DNA-bind_3 PF12776.7 pCP017854_00044 - 2 9.5 5.3 1.6 9.8 0.4 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Relaxase PF03432.14 pCP017854_00045 - 3.6e-10 39.9 7.2 3.6e-10 39.9 7.2 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP017854_00046 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP017854_00046 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP017854_00046 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP017854_00046 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP017854_00046 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pCP017854_00047 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP017854_00047 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP017854_00047 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide GTP_EFTU PF00009.27 pCP017857_00001 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP017857_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP017857_00001 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP017857_00001 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP017857_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP017857_00001 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP017857_00001 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP017857_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP017857_00001 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Sgf11 PF08209.11 pCP017857_00002 - 0.11 12.1 0.8 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) CtsR_C PF17727.1 pCP017857_00003 - 0.031 14.4 0.2 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Lip_prot_lig_C PF10437.9 pCP017857_00003 - 0.049 13.6 2.7 0.17 11.9 2.2 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus LysE PF01810.18 pCP017857_00004 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP017857_00004 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP017857_00004 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP017857_00004 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP017857_00004 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP017857_00004 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP017857_00004 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP017857_00004 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP017857_00004 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP017857_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP017857_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP017857_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP017857_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP017857_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP017857_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP017857_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP017857_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP017857_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP017857_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP017857_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP017857_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP017857_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP017857_00009 - 2.2e-16 59.5 2.2 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP017857_00009 - 5e-08 33.1 8.3 5e-08 33.1 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP017857_00009 - 9.5e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP017857_00009 - 1.1e-05 25.3 2.2 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP017857_00009 - 3.1e-05 24.4 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase DUF3800 PF12686.7 pCP017857_00010 - 6e-06 26.9 8.9 6e-06 26.9 8.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3800) CM_2 PF01817.21 pCP017857_00010 - 0.032 14.6 0.2 0.082 13.3 0.2 1.7 1 0 0 1 1 1 0 Chorismate mutase type II Myb_DNA-bind_3 PF12776.7 pCP017857_00010 - 2 9.5 5.3 1.6 9.8 0.4 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Relaxase PF03432.14 pCP017857_00011 - 3.6e-10 39.9 7.2 3.6e-10 39.9 7.2 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP017857_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP017857_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP017857_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP017857_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP017857_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pCP017857_00013 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP017857_00013 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP017857_00013 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pCP017857_00016 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP017857_00016 - 0.016 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP017857_00016 - 0.017 15.2 6.4 1.2 9.2 0.0 2.8 2 1 1 3 3 3 0 Apoptogenic protein 1 DUF4223 PF13978.6 pCP017857_00017 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP017857_00017 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 pCP017857_00018 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 pCP017857_00019 - 5.1e-29 101.4 6.3 9.5e-29 100.6 6.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pCP017857_00019 - 2e-26 92.8 0.9 3.2e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pCP017857_00019 - 4e-06 25.9 0.8 5.9e-06 25.3 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2841 PF11001.8 pCP017857_00019 - 0.0032 17.5 0.9 0.0087 16.1 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) RIO1 PF01163.22 pCP017857_00019 - 0.0073 15.9 2.5 0.0073 15.9 2.5 1.6 2 0 0 2 2 2 1 RIO1 family ORC6 PF05460.13 pCP017857_00019 - 0.0086 15.4 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Pectate_lyase_3 PF12708.7 pCP017857_00019 - 0.068 13.0 0.4 0.14 12.0 0.4 1.4 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pex19 PF04614.12 pCP017857_00019 - 3.6 7.3 5.4 7.5 6.2 5.4 1.5 1 0 0 1 1 1 0 Pex19 protein family HicB_lk_antitox PF15919.5 pCP017857_00021 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP017857_00021 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 pCP017857_00022 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP017857_00022 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP017857_00022 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP017857_00022 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP017857_00022 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP017857_00022 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pCP017857_00023 - 0.013 15.3 0.4 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pCP017857_00025 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP017857_00025 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP017857_00025 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP017857_00025 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP017857_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP017857_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP017857_00028 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP017857_00028 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP017857_00029 - 1.3e-51 175.6 0.7 3e-51 174.5 0.7 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP017857_00029 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP017857_00029 - 0.045 13.2 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP017857_00030 - 1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP017857_00030 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF3251 PF11622.8 pCP017857_00031 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP017857_00031 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP017857_00031 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP017857_00031 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP017857_00031 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP017857_00031 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP017857_00032 - 2.6e-25 88.5 0.1 3.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP017857_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP017857_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP017857_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP017857_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP017857_00034 - 5e-28 98.9 13.9 7.2e-28 98.3 13.9 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP017857_00034 - 0.0042 17.2 1.4 0.016 15.3 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP017857_00034 - 0.007 17.1 5.8 0.007 17.1 5.8 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pCP017857_00034 - 0.092 13.4 3.4 0.078 13.6 1.0 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pCP017857_00034 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pCP017857_00034 - 2.8 8.5 8.6 9.9 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TrbL PF04610.14 pCP017857_00035 - 4.7e-29 101.7 31.2 4.7e-29 101.7 31.2 1.8 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP017857_00035 - 0.22 11.3 1.3 0.79 9.6 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP017857_00035 - 1.7 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP017857_00036 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP017857_00036 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP017857_00037 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP017857_00037 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP017857_00038 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP017857_00038 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP017857_00039 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP017857_00039 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP017857_00040 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP017857_00040 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP017857_00040 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP017857_00040 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP017857_00040 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP017857_00040 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP017857_00040 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP017857_00040 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP017857_00040 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP017857_00040 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP017857_00040 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP017857_00040 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP017857_00040 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP017857_00040 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP017857_00040 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP017857_00040 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP017857_00040 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP017857_00040 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP017857_00040 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP017857_00040 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP017857_00040 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP017857_00040 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP017857_00040 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP017857_00040 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP017857_00040 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP017857_00040 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP017857_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP017857_00040 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP017857_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP017857_00040 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP017857_00040 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP017857_00041 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP017857_00041 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP017857_00041 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP017857_00041 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP017857_00042 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP017857_00042 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP017857_00042 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP017857_00042 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP017857_00043 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP017857_00044 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP017857_00044 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP017857_00044 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP017857_00046 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP017857_00047 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP017857_00047 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 pCP017857_00047 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 pCP017857_00047 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 pCP017857_00047 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP017857_00047 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pCP017857_00048 - 5.1e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP017857_00048 - 0.02 14.8 3.9 0.17 11.9 3.9 2.6 1 1 0 1 1 1 0 Intein splicing domain IMS PF00817.20 pCP018901_00001 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family DUF4368 PF14287.6 pCP018901_00002 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 pCP018901_00002 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.3 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 pCP018901_00002 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 pCP018901_00002 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 pCP018901_00002 - 0.12 12.5 0.5 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 TnpV PF14198.6 pCP018901_00003 - 3.3e-41 139.8 0.5 3.6e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV AAA_18 PF13238.6 pCP018901_00004 - 1.2e-14 55.0 0.0 1.5e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pCP018901_00004 - 2.4e-11 44.0 0.0 2.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP018901_00004 - 2.8e-10 40.3 0.0 5.4e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 pCP018901_00004 - 1.5e-07 30.9 0.0 3.1e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 pCP018901_00004 - 3.6e-06 27.3 0.2 9.9e-06 25.9 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 pCP018901_00004 - 8.3e-06 26.3 0.0 5.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 pCP018901_00004 - 8.6e-06 26.2 0.0 3.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pCP018901_00004 - 1.5e-05 25.3 0.0 5.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pCP018901_00004 - 5.9e-05 23.1 0.0 8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pCP018901_00004 - 0.00029 21.2 0.0 0.00036 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pCP018901_00004 - 0.00097 18.5 0.3 0.0011 18.2 0.3 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 pCP018901_00004 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 pCP018901_00004 - 0.0016 18.0 0.1 0.0034 16.9 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 pCP018901_00004 - 0.0021 17.8 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP018901_00004 - 0.0022 17.8 0.3 0.0036 17.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pCP018901_00004 - 0.0025 18.3 0.0 0.0029 18.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.13 pCP018901_00004 - 0.0047 16.2 0.3 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain APS_kinase PF01583.20 pCP018901_00004 - 0.0047 16.8 0.0 0.088 12.7 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase ATPase PF06745.13 pCP018901_00004 - 0.0061 15.9 0.7 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 pCP018901_00004 - 0.011 14.9 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DnaB_C PF03796.15 pCP018901_00004 - 0.015 14.7 0.5 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 pCP018901_00004 - 0.015 14.9 0.1 0.033 13.8 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 pCP018901_00004 - 0.015 15.2 0.1 0.93 9.4 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 pCP018901_00004 - 0.016 15.1 0.5 0.031 14.2 0.2 1.6 2 0 0 2 2 1 0 NTPase Viral_helicase1 PF01443.18 pCP018901_00004 - 0.016 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 pCP018901_00004 - 0.018 14.8 0.1 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 pCP018901_00004 - 0.018 14.6 0.3 0.066 12.8 0.1 2.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 pCP018901_00004 - 0.024 14.8 0.2 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.15 pCP018901_00004 - 0.03 14.3 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Hydin_ADK PF17213.3 pCP018901_00004 - 0.032 14.5 0.7 0.05 13.9 0.2 1.5 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain NB-ARC PF00931.22 pCP018901_00004 - 0.037 13.2 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MKT1_N PF12247.8 pCP018901_00004 - 0.04 14.3 0.0 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication ArsA_ATPase PF02374.15 pCP018901_00004 - 0.042 13.0 0.1 0.089 12.0 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase NACHT PF05729.12 pCP018901_00004 - 0.045 13.7 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 pCP018901_00004 - 0.046 13.5 1.0 0.067 13.0 0.9 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 pCP018901_00004 - 0.047 14.1 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 pCP018901_00004 - 0.053 13.2 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GvpD PF07088.11 pCP018901_00004 - 0.054 12.1 0.3 0.38 9.3 0.0 2.1 2 1 1 3 3 3 0 GvpD gas vesicle protein AAA_7 PF12775.7 pCP018901_00004 - 0.056 13.0 0.2 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 pCP018901_00004 - 0.073 12.8 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 pCP018901_00004 - 0.076 12.5 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase1 PF18748.1 pCP018901_00004 - 0.086 12.4 0.0 2 7.9 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 ATP-synt_ab PF00006.25 pCP018901_00004 - 0.086 12.5 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IPT PF01745.16 pCP018901_00004 - 0.098 12.0 0.2 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 Isopentenyl transferase Ploopntkinase3 PF18751.1 pCP018901_00004 - 0.11 12.4 0.4 0.37 10.7 0.0 2.0 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 pCP018901_00004 - 0.18 11.5 0.7 10 5.7 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase APH PF01636.23 pCP018901_00005 - 8.6e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP018901_00005 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP018901_00005 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP018901_00005 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP018901_00005 - 0.09 12.4 0.4 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP018901_00005 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP018901_00006 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pCP018901_00007 - 6.8e-11 42.6 0.0 8.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP018901_00007 - 0.014 14.6 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase CPT PF07931.12 pCP018901_00008 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 pCP018901_00008 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pCP018901_00008 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pCP018901_00008 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 pCP018901_00008 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3847 PF12958.7 pCP018901_00009 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 pCP018901_00009 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 pCP018901_00009 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 pCP018901_00009 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MobA_MobL PF03389.15 pCP018901_00010 - 3.5e-50 170.8 0.0 3.9e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 MobA/MobL family AAA_25 PF13481.6 pCP018901_00011 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 pCP018901_00011 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 pCP018901_00011 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 pCP018901_00011 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 pCP018901_00011 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 pCP018901_00011 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 pCP018901_00011 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 pCP018901_00011 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 pCP018901_00011 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 pCP018901_00011 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 pCP018901_00011 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 pCP018901_00011 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 pCP018901_00011 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 pCP018901_00011 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 pCP018901_00011 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 pCP018901_00011 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 pCP018901_00011 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IMS_C PF11799.8 pCP018901_00012 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 pCP018901_00012 - 0.00028 21.0 0.1 0.00067 19.8 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF447 PF04289.12 pCP018901_00014 - 0.029 14.2 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pCP018901_00014 - 0.032 14.1 0.3 0.049 13.6 0.2 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pCP018901_00014 - 0.04 14.0 0.1 0.054 13.6 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3825 PF12873.7 pCP018901_00015 - 4.2e-29 101.7 0.3 6.7e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) SGT1 PF07093.11 pCP018901_00017 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 pCP018901_00017 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 pCP018901_00017 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5309 PF17236.2 pCP018901_00018 - 3.1e-05 23.5 0.5 3.3e-05 23.4 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5309) HicA_toxin PF07927.12 pCP018901_00019 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP018901_00020 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pCP018901_00020 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ParE_toxin PF05016.15 pCP018901_00022 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 pCP018901_00024 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF4131 PF13567.6 pCP018901_00025 - 0.0008 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 pCP018901_00025 - 0.015 15.2 3.3 0.019 14.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 pCP018901_00025 - 0.056 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2663 PF10864.8 pCP018901_00025 - 0.13 12.7 2.1 0.16 12.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2721 PF11026.8 pCP018901_00025 - 0.27 11.1 5.3 0.34 10.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TraG_N PF07916.11 pCP018901_00026 - 8.5e-39 133.7 20.1 8.5e-39 133.7 20.1 3.3 3 1 0 4 4 4 1 TraG-like protein, N-terminal region Glyco_tranf_2_5 PF13712.6 pCP018901_00027 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family UvrA_DNA-bind PF17755.1 pCP018901_00028 - 0.00087 19.6 0.5 0.32 11.4 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain SseC PF04888.12 pCP018901_00030 - 0.0051 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 pCP018901_00030 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter APOBEC_C PF05240.14 pCP018901_00030 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Hormone_2 PF00123.20 pCP018901_00030 - 0.035 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone Phage_lysozyme PF00959.19 pCP018901_00032 - 1.2e-10 41.8 1.2 1.9e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Phage lysozyme Vta1 PF04652.16 pCP018901_00032 - 2.2 8.3 10.2 0.054 13.5 1.0 2.9 3 1 1 4 4 4 0 Vta1 like DUF2974 PF11187.8 pCP018901_00033 - 1.4e-06 28.0 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 pCP018901_00033 - 1e-05 25.4 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 pCP018901_00033 - 0.0019 17.7 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pCP018901_00033 - 0.0036 17.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF4450 PF14614.6 pCP018901_00033 - 0.016 14.8 0.2 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4450) UPF0227 PF05728.12 pCP018901_00033 - 0.028 14.4 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 pCP018901_00033 - 0.028 13.0 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 pCP018901_00033 - 0.049 14.2 0.0 0.069 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 pCP018901_00034 - 0.0024 17.4 0.1 0.007 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pCP018901_00034 - 0.05 13.1 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 pCP018901_00034 - 0.11 12.3 0.1 0.44 10.4 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 3) DUF3810 PF12725.7 pCP018901_00035 - 0.0026 17.2 5.2 0.0029 17.0 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) CitMHS PF03600.16 pCP018901_00035 - 0.023 13.9 0.3 0.023 13.9 0.3 1.0 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 pCP018901_00035 - 0.11 12.2 5.7 0.16 11.7 5.7 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 pCP018901_00035 - 1.8 7.9 10.7 4.1 6.8 10.3 1.8 1 1 0 1 1 1 0 Spo7-like protein Lipase_3 PF01764.25 pCP018901_00038 - 1.5e-08 34.6 0.0 5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pCP018901_00038 - 3.1e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pCP018901_00038 - 1.1e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pCP018901_00038 - 5.6e-05 23.0 0.1 9.7e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 pCP018901_00038 - 0.00041 20.0 0.1 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pCP018901_00038 - 0.00064 20.4 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pCP018901_00038 - 0.0014 18.6 0.3 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 pCP018901_00038 - 0.014 15.3 1.8 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase NMT PF01233.19 pCP018901_00038 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Hydrolase_4 PF12146.8 pCP018901_00038 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 pCP018901_00038 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Put_DNA-bind_N PF06971.13 pCP018901_00042 - 0.039 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus ATG27 PF09451.10 pCP018901_00042 - 0.071 13.0 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Toprim_3 PF13362.6 pCP018901_00044 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP018901_00044 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pCP018901_00044 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pCP018901_00044 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Abi_2 PF07751.11 pCP018901_00045 - 0.0013 19.1 11.1 0.002 18.4 11.1 1.3 1 0 0 1 1 1 1 Abi-like protein NYN PF01936.18 pCP018901_00046 - 1.7e-10 41.6 0.0 1.9e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pCP018901_00046 - 0.0082 16.0 0.7 0.016 15.1 0.7 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pCP018901_00046 - 0.02 15.5 0.0 0.035 14.8 0.0 1.4 1 0 0 1 1 1 0 PIN domain RHH_7 PF16777.5 pCP018901_00047 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pCP018901_00047 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 pCP018901_00048 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP018901_00048 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP018901_00048 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pCP018901_00048 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF4223 PF13978.6 pCP018901_00049 - 0.21 11.6 1.5 0.36 10.8 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) ZapB PF06005.12 pCP018901_00050 - 0.094 13.2 0.1 0.095 13.2 0.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF1451 PF07295.11 pCP018901_00051 - 0.00056 20.0 0.0 0.00063 19.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain DUF4145 PF13643.6 pCP018901_00052 - 8.2e-17 61.1 3.4 1.4e-15 57.1 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4145) HicB_lk_antitox PF15919.5 pCP018901_00054 - 1.8e-08 34.5 0.0 2e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP018901_00054 - 0.075 12.4 0.0 0.082 12.3 0.0 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain HicA_toxin PF07927.12 pCP018901_00055 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP018901_00056 - 1.7e-15 57.2 0.0 3.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP018901_00056 - 0.00066 19.1 0.0 0.0072 15.7 0.0 2.2 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP018901_00056 - 0.0016 18.2 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP018901_00056 - 0.0031 17.3 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pCP018901_00056 - 0.0057 16.0 0.1 0.044 13.1 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP018901_00056 - 0.07 13.6 0.7 0.9 10.0 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP018901_00056 - 0.16 12.0 1.2 0.59 10.2 1.2 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1947 PF09183.10 pCP018901_00056 - 0.7 10.2 6.3 1.7 9.0 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) RHH_7 PF16777.5 pCP018901_00057 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pCP018901_00057 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 pCP018901_00058 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP018901_00058 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP018901_00058 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pCP018901_00058 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF4995 PF16386.5 pCP018901_00059 - 0.14 12.2 0.7 0.15 12.1 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF4223 PF13978.6 pCP018901_00059 - 0.2 11.6 1.9 0.28 11.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) CitMHS PF03600.16 pCP018901_00064 - 0.0018 17.5 0.1 0.0018 17.5 0.1 1.0 1 0 0 1 1 1 1 Citrate transporter DUF3810 PF12725.7 pCP018901_00064 - 0.0049 16.3 5.3 0.0058 16.0 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Yip1 PF04893.17 pCP018901_00064 - 0.24 11.1 5.6 0.37 10.5 5.6 1.2 1 0 0 1 1 1 0 Yip1 domain Ion_trans PF00520.31 pCP018901_00064 - 1.4 8.1 14.4 1.7 7.8 14.4 1.5 1 1 0 1 1 1 0 Ion transport protein DHHC PF01529.20 pCP018901_00064 - 1.8 8.6 10.9 3.1 7.9 10.9 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Spo7 PF03907.13 pCP018901_00064 - 2.8 7.4 6.8 5.6 6.4 6.8 1.5 1 0 0 1 1 1 0 Spo7-like protein CitMHS PF03600.16 pCP018901_00066 - 0.0033 16.7 0.5 0.0039 16.4 0.5 1.1 1 0 0 1 1 1 1 Citrate transporter Yip1 PF04893.17 pCP018901_00066 - 0.4 10.4 6.1 0.57 9.9 6.1 1.1 1 0 0 1 1 1 0 Yip1 domain DUF3810 PF12725.7 pCP018901_00066 - 0.43 9.9 11.7 0.55 9.5 11.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Ion_trans PF00520.31 pCP018901_00066 - 0.5 9.5 12.3 0.78 8.9 12.2 1.4 1 1 0 1 1 1 0 Ion transport protein Spo7 PF03907.13 pCP018901_00066 - 2.2 7.7 7.5 3.7 7.0 7.5 1.5 1 1 0 1 1 1 0 Spo7-like protein DHHC PF01529.20 pCP018901_00066 - 3.4 7.8 11.8 6.4 6.9 11.8 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Phage_lysozyme PF00959.19 pCP018901_00067 - 2.1e-10 41.0 2.1 6e-10 39.6 0.1 2.9 2 0 0 2 2 2 1 Phage lysozyme Lipase_3 PF01764.25 pCP018901_00067 - 2.8e-07 30.5 0.0 1e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 pCP018901_00067 - 0.00084 19.1 2.0 0.003 17.3 0.0 2.8 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 pCP018901_00067 - 0.096 13.3 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 pCP018901_00067 - 0.2 11.8 0.0 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain SseC PF04888.12 pCP018901_00069 - 0.014 15.1 0.2 0.014 15.1 0.2 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ThrE PF06738.12 pCP018901_00069 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter APOBEC_C PF05240.14 pCP018901_00069 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Hormone_2 PF00123.20 pCP018901_00069 - 0.035 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone UvrA_DNA-bind PF17755.1 pCP018901_00070 - 0.0051 17.1 0.3 3.2 8.1 0.0 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 pCP018901_00071 - 0.013 15.8 0.2 6.8 7.1 0.1 2.6 2 0 0 2 2 2 0 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 pCP018901_00073 - 0.025 14.9 0.6 11 6.4 0.1 2.7 3 0 0 3 3 3 0 UvrA DNA-binding domain DUF3870 PF12986.7 pCP018901_00073 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) FHA PF00498.26 pCP018901_00074 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pCP018901_00074 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pCP018901_00074 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain ImcF-related_N PF14331.6 pCP018901_00075 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pCP018901_00075 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pCP018901_00075 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pCP018901_00075 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pCP018901_00075 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pCP018901_00075 - 0.0033 17.1 5.0 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pCP018901_00075 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain T6SS_HCP PF05638.12 pCP018901_00076 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp DotU PF09850.9 pCP018901_00077 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_VasE PF05936.12 pCP018901_00078 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE T6SS-SciN PF12790.7 pCP018901_00079 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasJ PF16989.5 pCP018901_00080 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pCP018901_00080 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pCP018901_00080 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 pCP018901_00080 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS_VipA PF05591.12 pCP018901_00081 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pCP018901_00081 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase VipB PF05943.12 pCP018901_00082 - 7.4e-170 565.3 0.0 8.7e-170 565.1 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pCP018901_00082 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide GPW_gp25 PF04965.14 pCP018901_00083 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pCP018901_00083 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pCP018901_00083 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) T6SS_TssF PF05947.12 pCP018901_00084 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF T6SS_TssG PF06996.11 pCP018901_00085 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG Phage_GPD PF05954.11 pCP018901_00086 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 pCP018901_00086 - 0.011 15.7 1.7 0.029 14.2 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Gp5_C PF06715.12 pCP018901_00086 - 0.013 15.6 4.6 0.19 11.9 0.1 4.0 2 1 2 4 4 4 0 Gp5 C-terminal repeat (3 copies) DUF3540 PF12059.8 pCP018901_00086 - 0.1 12.4 0.8 0.45 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) TCL1_MTCP1 PF01840.17 pCP018901_00086 - 0.1 12.2 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 TCL1/MTCP1 family Ank_3 PF13606.6 pCP018901_00087 - 2.8e-10 39.5 0.1 0.00091 19.5 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 pCP018901_00087 - 3.8e-09 37.0 0.0 2.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 pCP018901_00087 - 1.9e-05 25.1 0.0 0.0011 19.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 pCP018901_00087 - 7.3e-05 23.0 0.0 2.5 8.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pCP018901_00087 - 0.0034 17.6 0.3 0.13 12.7 0.0 3.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pCP018901_00088 - 6.6e-08 32.8 0.0 6.6e-08 32.8 0.0 3.0 2 1 1 3 3 3 1 Restriction endonuclease fold toxin 7 Ank_2 PF12796.7 pCP018901_00089 - 1.3e-11 44.9 0.5 1.1e-06 29.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pCP018901_00089 - 4.9e-10 38.8 0.4 0.0091 16.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 pCP018901_00089 - 0.0015 19.1 0.1 0.31 11.7 0.0 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 pCP018901_00089 - 0.0038 17.6 0.0 18 6.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 pCP018901_00089 - 0.023 15.0 0.1 1.5 9.2 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pCP018901_00090 - 1.4e-07 31.7 4.9 1.7e-07 31.5 0.0 3.6 2 1 1 3 3 3 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 pCP018901_00090 - 0.57 9.9 6.5 1.6 8.5 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Ank_2 PF12796.7 pCP018901_00091 - 5.5e-13 49.3 0.5 1.3e-07 32.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pCP018901_00091 - 5.8e-11 41.6 0.3 0.00054 20.2 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 pCP018901_00091 - 1.9e-05 24.9 0.0 1.1 9.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 pCP018901_00091 - 6.7e-05 23.4 0.2 0.018 15.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FAM25 PF15825.5 pCP018901_00091 - 0.0037 17.6 1.6 2.4 8.6 0.2 2.7 2 0 0 2 2 2 2 FAM25 family Ank_5 PF13857.6 pCP018901_00091 - 0.028 14.7 0.1 0.82 10.1 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (many copies) TNT PF14021.6 pCP018901_00094 - 1.5e-15 57.5 0.0 1.1e-08 35.5 0.0 2.3 2 0 0 2 2 2 2 Tuberculosis necrotizing toxin LPD7 PF18821.1 pCP018901_00095 - 0.032 14.3 0.5 3.1 8.0 0.1 2.4 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 pCP018901_00095 - 1.1 9.8 8.9 1.5 9.4 2.6 3.0 1 1 2 3 3 3 0 Immunity protein 59 AHH PF14412.6 pCP018901_00096 - 1e-15 57.8 1.5 2e-15 56.9 1.5 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Ntox24 PF15529.6 pCP018901_00099 - 0.003 17.8 1.3 0.0048 17.2 0.3 1.9 2 0 0 2 2 2 1 Bacterial toxin 24 CobN-Mg_chel PF02514.16 pCP018901_00100 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Imm59 PF15597.6 pCP018901_00101 - 0.054 14.0 8.6 0.12 12.9 1.7 2.2 1 1 1 2 2 2 0 Immunity protein 59 AHH PF14412.6 pCP018901_00102 - 5.7e-17 61.8 2.0 1.1e-16 60.9 2.0 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pCP018901_00102 - 0.25 11.3 7.2 0.13 12.2 1.5 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF4299 PF14132.6 pCP018901_00104 - 1.4e-08 34.5 0.1 1.6e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) XPG_I PF00867.18 pCP018901_00104 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region Phage_GPD PF05954.11 pCP018901_00106 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pCP018901_00106 - 0.081 12.6 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family BaxI_1 PF12811.7 pCP018901_00108 - 0.28 10.7 13.0 0.43 10.1 12.5 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like CrgA PF06781.12 pCP018901_00108 - 0.43 10.7 6.3 0.5 10.5 4.6 2.0 2 0 0 2 2 2 0 Cell division protein CrgA Peripla_BP_2 PF01497.18 pCP018901_00109 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF2345 PF10106.9 pCP018901_00109 - 0.029 14.3 0.4 0.27 11.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DZR PF12773.7 pCP018901_00113 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 pCP018901_00113 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 pCP018901_00113 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rapsyn_N PF10579.9 pCP018901_00114 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SprT-like PF10263.9 pCP018901_00116 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 pCP018901_00116 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain Phage_integrase PF00589.22 pCP018901_00119 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pCP018901_00119 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pCP018901_00119 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 pCP018901_00119 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 pCP018901_00119 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 pCP018901_00119 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlaC_arch PF05377.11 pCP018901_00120 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) WGR PF05406.15 pCP018901_00121 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pCP018901_00121 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like YafQ_toxin PF15738.5 pCP018901_00125 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pCP018901_00125 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 pCP018901_00125 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 pCP018901_00125 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system CCDC-167 PF15188.6 pCP018901_00130 - 0.0044 17.3 0.4 0.0077 16.6 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 pCP018901_00130 - 0.018 15.1 3.2 0.049 13.8 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) Sigma_reg_N PF13800.6 pCP018901_00131 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5601 PF18151.1 pCP018901_00132 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 pCP018901_00132 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) HTH_3 PF01381.22 pCP018901_00134 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pCP018901_00134 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pCP018901_00134 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 pCP018901_00134 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pCP018901_00134 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pCP018901_00134 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pCP018901_00134 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pCP018901_00134 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pCP018901_00134 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pCP018901_00134 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pCP018901_00134 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pCP018901_00134 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pCP018901_00134 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 pCP018901_00134 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 pCP018901_00134 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 pCP018901_00134 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 pCP018901_00134 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 pCP018901_00134 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pCP018901_00134 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pCP018901_00134 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain SNF2_N PF00176.23 pCP020479_00001 - 4.6e-14 51.9 0.1 1.8e-13 49.9 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Eco57I PF07669.11 pCP020479_00001 - 2.4e-09 37.6 1.8 4.5e-07 30.3 0.0 4.8 3 0 0 3 3 3 1 Eco57I restriction-modification methylase Helicase_C PF00271.31 pCP020479_00001 - 2.2e-06 28.0 0.9 3.6e-05 24.1 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP020479_00001 - 0.0037 17.1 2.5 0.01 15.6 0.1 2.9 2 1 0 3 3 3 1 DEAD/DEAH box helicase Methyltransf_23 PF13489.6 pCP020479_00001 - 0.0041 17.0 0.1 0.049 13.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 pCP020479_00001 - 0.0059 16.2 0.0 0.019 14.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase small domain Hydrolase PF00702.26 pCP020479_00001 - 0.1 12.8 1.1 5.2 7.3 0.2 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase AbiEi_4 PF13338.6 pCP020479_00002 - 6.2e-05 23.1 0.0 0.00031 20.8 0.0 2.1 3 0 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin AbiEii PF08843.11 pCP020479_00003 - 5.5e-30 105.1 0.1 8e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system JmjN PF02375.17 pCP020479_00004 - 1.2 9.2 3.8 17 5.5 0.1 2.7 2 1 1 3 3 3 0 jmjN domain MtrG PF04210.13 pCP020479_00004 - 1.2 9.1 5.1 0.8 9.6 0.7 2.2 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G RelB PF04221.12 pCP020479_00005 - 2.1e-09 37.2 0.0 2.6e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 RelB antitoxin ParE_toxin PF05016.15 pCP020479_00006 - 2.7e-05 24.7 0.5 3e-05 24.5 0.5 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Apolipoprotein PF01442.18 pCP020479_00007 - 0.00016 21.6 2.2 0.00016 21.6 2.2 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain PP_kinase PF02503.17 pCP020479_00007 - 0.011 15.3 0.7 0.011 15.3 0.7 1.7 2 0 0 2 2 2 0 Polyphosphate kinase middle domain T3SSipB PF16535.5 pCP020479_00007 - 0.025 15.0 0.3 0.053 14.0 0.3 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB Thump_like PF18096.1 pCP020479_00007 - 0.046 13.6 0.6 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 THUMP domain-like Fib_alpha PF08702.10 pCP020479_00007 - 7.7 6.7 9.5 1.8 8.8 5.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 pCP020479_00007 - 8.3 6.8 12.9 1.9 8.8 7.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein NYN PF01936.18 pCP020479_00008 - 2.8e-10 40.8 1.4 9.5e-10 39.1 1.4 1.8 1 1 0 1 1 1 1 NYN domain Tn7_Tnp_TnsA_C PF08721.11 pCP020479_00008 - 0.0029 18.2 1.9 0.42 11.3 0.3 2.5 2 0 0 2 2 2 2 TnsA endonuclease C terminal TMPIT PF07851.13 pCP020479_00008 - 0.078 12.2 2.2 0.11 11.7 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein ApbA PF02558.16 pCP020479_00008 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Vir_act_alpha_C PF10400.9 pCP020479_00008 - 0.28 11.9 1.6 0.57 10.9 1.1 1.8 1 1 1 2 2 2 0 Virulence activator alpha C-term UvrD_C PF13361.6 pCP020479_00009 - 8e-16 58.3 3.4 4.2e-11 42.8 0.2 2.6 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 pCP020479_00009 - 2.3e-12 47.5 0.0 8.7e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 pCP020479_00009 - 2e-09 37.6 1.2 0.0027 17.5 0.3 3.4 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 pCP020479_00009 - 5.4e-09 36.0 22.6 1.6e-07 31.2 2.9 4.2 2 2 1 4 4 4 3 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 pCP020479_00009 - 1.2e-06 28.2 0.0 0.055 13.3 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 pCP020479_00009 - 5.1e-05 23.1 0.0 0.00021 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 pCP020479_00009 - 0.0028 17.7 3.3 0.0028 17.7 3.3 2.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.16 pCP020479_00009 - 0.0036 16.8 0.4 1.1 8.7 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 pCP020479_00009 - 0.024 14.9 0.2 0.14 12.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 pCP020479_00009 - 0.15 11.8 0.2 2.3 7.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Fic PF02661.18 pCP020479_00011 - 3.8e-13 50.1 0.5 2.1e-12 47.8 0.0 2.4 3 0 0 3 3 3 1 Fic/DOC family Tli4_N PF18443.1 pCP020479_00011 - 3.3 8.1 9.6 1.3 9.4 6.2 2.1 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain YopX PF09643.10 pCP020479_00012 - 4.1e-12 46.3 6.8 3.1e-11 43.5 4.1 2.2 1 1 1 2 2 2 2 YopX protein TMF_DNA_bd PF12329.8 pCP020479_00013 - 0.00073 19.5 18.5 0.00073 19.5 18.5 7.0 3 1 3 6 6 6 1 TATA element modulatory factor 1 DNA binding DUF386 PF04074.12 pCP020479_00014 - 0.024 14.5 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 YhcH/YjgK/YiaL AAA_31 PF13614.6 pCP020479_00015 - 8.4e-18 64.9 2.1 3.1e-11 43.5 0.0 2.7 1 1 1 3 3 3 2 AAA domain CbiA PF01656.23 pCP020479_00015 - 6e-17 61.9 0.2 8.6e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 pCP020479_00015 - 7.9e-15 54.8 0.3 1.3e-06 28.0 0.0 2.4 2 1 0 3 3 3 2 ATPase MipZ VirC1 PF07015.11 pCP020479_00015 - 5.1e-07 29.2 0.0 7.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 VirC1 protein ParA PF10609.9 pCP020479_00015 - 1.5e-06 27.9 0.2 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CLP1_P PF16575.5 pCP020479_00015 - 5.2e-05 23.1 0.0 0.00091 19.1 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ArsA_ATPase PF02374.15 pCP020479_00015 - 0.00018 20.8 0.3 0.0003 20.1 0.1 1.5 1 1 0 1 1 1 1 Anion-transporting ATPase SRP54 PF00448.22 pCP020479_00015 - 0.00025 20.7 1.1 0.0011 18.7 0.4 2.2 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 pCP020479_00015 - 0.016 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 pCP020479_00015 - 0.016 14.6 0.0 0.038 13.4 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1188 PF06690.11 pCP020479_00015 - 0.057 13.0 2.3 0.081 12.5 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1188) AAA_26 PF13500.6 pCP020479_00015 - 0.089 12.6 1.2 6.3 6.6 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 pCP020479_00015 - 0.098 13.2 0.6 1.3 9.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain PAC2 PF09754.9 pCP020479_00015 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 PAC2 family DUF4271 PF14093.6 pCP020479_00016 - 0.0013 18.7 1.3 0.0017 18.3 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) SLAC1 PF03595.17 pCP020479_00016 - 0.0015 17.9 2.7 0.002 17.4 2.8 1.3 1 1 0 1 1 1 1 Voltage-dependent anion channel PEN-2 PF10251.9 pCP020479_00016 - 0.0075 16.7 0.7 0.014 15.8 0.5 1.6 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase DUF3413 PF11893.8 pCP020479_00016 - 0.028 13.6 2.1 0.029 13.5 1.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) DUF456 PF04306.13 pCP020479_00016 - 0.033 14.5 4.7 0.058 13.7 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF456) TctB PF07331.11 pCP020479_00016 - 0.17 12.1 8.2 0.32 11.3 8.2 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF1772 PF08592.11 pCP020479_00016 - 0.25 11.7 2.0 0.22 11.8 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4405 PF14358.6 pCP020479_00016 - 4.8 7.8 8.7 2.9 8.5 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) TSNAXIP1_N PF15739.5 pCP020479_00017 - 0.012 16.0 2.3 0.015 15.7 2.3 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus CsoSCA PF08936.10 pCP020479_00017 - 0.045 12.4 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase SPC12 PF06645.13 pCP020479_00018 - 0.33 11.1 8.5 0.082 13.0 3.5 2.3 1 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Arteri_Gl PF00951.18 pCP020479_00018 - 8.1 6.2 11.4 4.8 7.0 2.1 2.2 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein DUF4521 PF15021.6 pCP020479_00019 - 0.007 16.3 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) SOAR PF16533.5 pCP020479_00020 - 0.023 14.7 1.5 0.023 14.7 1.5 1.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region zf-RING_9 PF13901.6 pCP020479_00020 - 0.071 13.1 3.2 0.095 12.7 3.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Pro-rich_19 PF15455.6 pCP020479_00020 - 0.098 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 DUF2959 PF11172.8 pCP020479_00020 - 0.21 11.7 8.6 0.048 13.8 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) DASH_Hsk3 PF08227.11 pCP020479_00020 - 0.79 10.1 3.9 3.4 8.1 0.1 3.3 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like DUF1664 PF07889.12 pCP020479_00020 - 1.2 9.1 7.2 13 5.9 1.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 pCP020479_00020 - 3.4 7.8 6.7 29 4.8 3.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SpoIIIAH PF12685.7 pCP020479_00021 - 0.00058 19.7 1.1 0.0008 19.3 1.1 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein ASFV_J13L PF05568.11 pCP020479_00021 - 0.0095 15.7 0.3 0.016 15.0 0.3 1.4 1 1 0 1 1 1 1 African swine fever virus J13L protein Baculo_F PF12259.8 pCP020479_00022 - 0.02 13.4 0.7 0.021 13.4 0.7 1.0 1 0 0 1 1 1 0 Baculovirus F protein CcdA PF07362.12 pCP020479_00022 - 0.031 14.7 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Phage_Mu_Gam PF07352.12 pCP020479_00022 - 0.086 12.7 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Yae1_N PF09811.9 pCP020479_00023 - 0.86 9.4 2.9 0.44 10.3 0.2 1.9 3 0 0 3 3 3 0 Essential protein Yae1, N terminal DUF5638 PF18688.1 pCP020479_00026 - 0.0095 16.2 6.4 0.45 10.8 0.3 2.8 3 0 0 3 3 3 2 Family of unknown function (DUF5638) YvrJ PF12841.7 pCP020479_00027 - 2.2 7.9 5.6 4.7 6.8 0.1 2.7 3 0 0 3 3 3 0 YvrJ protein family Phage_holin_6_1 PF09682.10 pCP020479_00028 - 0.015 15.7 0.2 0.017 15.5 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) TMEM151 PF14857.6 pCP020479_00028 - 0.029 13.3 0.0 0.031 13.2 0.0 1.0 1 0 0 1 1 1 0 TMEM151 family Mlo PF03094.15 pCP020479_00028 - 0.033 12.6 0.2 0.035 12.5 0.2 1.0 1 0 0 1 1 1 0 Mlo family Na_Ala_symp PF01235.17 pCP020479_00028 - 0.047 13.0 0.0 0.053 12.8 0.0 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family Yae1_N PF09811.9 pCP020479_00029 - 0.42 10.3 4.8 0.15 11.8 2.0 1.7 2 0 0 2 2 2 0 Essential protein Yae1, N terminal DUF4234 PF14018.6 pCP020479_00030 - 0.033 14.3 1.1 0.049 13.8 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Ribosomal_L44 PF00935.19 pCP020479_00031 - 0.1 13.1 0.6 0.1 13.1 0.6 2.1 2 1 1 3 3 3 0 Ribosomal protein L44 Imm8 PF15586.6 pCP020479_00032 - 0.034 14.2 0.8 0.14 12.2 0.1 2.3 2 1 0 2 2 2 0 Immunity protein 8 Orthopox_F7 PF05813.12 pCP020479_00032 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Orthopoxvirus F7 protein PYST-C1 PF09690.10 pCP020479_00032 - 1.1 9.0 7.2 2.7 7.8 7.2 1.6 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) T3SSipB PF16535.5 pCP020479_00032 - 4.3 7.8 13.9 4.1 7.9 10.1 2.5 2 1 0 2 2 2 0 Type III cell invasion protein SipB Remorin_C PF03763.13 pCP020479_00033 - 0.76 9.7 6.9 2.8 7.9 0.4 2.9 3 0 0 3 3 3 0 Remorin, C-terminal region Corona_NS3b PF03053.14 pCP020479_00034 - 0.0098 15.7 0.2 0.011 15.5 0.2 1.1 1 0 0 1 1 1 1 ORF3b coronavirus protein DUF5058 PF16481.5 pCP020479_00034 - 0.042 13.6 0.2 0.044 13.5 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) MscS_TM PF12794.7 pCP020479_00034 - 0.052 12.4 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MBOAT_2 PF13813.6 pCP020479_00034 - 0.061 13.6 0.1 0.083 13.2 0.1 1.1 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family ETRAMP PF09716.10 pCP020479_00035 - 0.021 14.9 0.2 0.024 14.7 0.2 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Baculo_PEP_C PF04513.12 pCP020479_00037 - 0.19 11.8 7.2 0.29 11.2 7.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B558a PF05038.13 pCP020479_00038 - 0.0086 15.7 0.0 0.0099 15.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit DUF3040 PF11239.8 pCP020479_00038 - 0.3 11.4 1.4 0.33 11.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF746 PF05344.11 pCP020479_00039 - 0.045 13.6 0.0 0.046 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Tetraspanin PF00335.20 pCP020479_00041 - 0.022 14.5 0.0 0.023 14.4 0.0 1.0 1 0 0 1 1 1 0 Tetraspanin family Saf_2TM PF18303.1 pCP020479_00041 - 0.041 13.5 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain OPA3 PF07047.12 pCP020479_00041 - 0.075 12.8 0.0 0.095 12.5 0.0 1.1 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) LapA_dom PF06305.11 pCP020479_00041 - 0.078 12.8 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CPSase_L_D2 PF02786.17 pCP020479_00042 - 0.0071 15.9 0.3 0.0097 15.4 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AAA_23 PF13476.6 pCP020479_00042 - 0.074 13.6 6.5 0.1 13.1 6.0 1.5 1 1 0 1 1 1 0 AAA domain PBECR3 PF18812.1 pCP020479_00042 - 0.19 11.7 6.8 0.079 12.9 3.5 2.0 1 1 1 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 RecG_N PF17190.4 pCP020479_00042 - 0.29 11.9 3.6 0.38 11.5 0.4 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain DUF5301 PF17225.3 pCP020479_00042 - 4.5 7.8 8.1 18 5.9 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5300) Tape_meas_lam_C PF09718.10 pCP020479_00043 - 0.12 12.5 0.3 0.19 11.9 0.3 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SLT PF01464.20 pCP020479_00044 - 3.3e-14 52.5 0.1 4.8e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain MFS_Mycoplasma PF07672.13 pCP020479_00046 - 0.0037 16.6 0.3 0.0037 16.6 0.3 1.0 1 0 0 1 1 1 1 Mycoplasma MFS transporter OSTMP1 PF09777.9 pCP020479_00046 - 0.0094 15.4 0.1 0.0094 15.4 0.1 1.0 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor DUF3139 PF11337.8 pCP020479_00046 - 0.0097 16.5 0.6 0.012 16.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) ATP-synt_8 PF00895.20 pCP020479_00046 - 0.07 13.6 1.9 0.088 13.3 1.9 1.1 1 0 0 1 1 1 0 ATP synthase protein 8 Presenilin PF01080.17 pCP020479_00046 - 1 8.0 3.9 0.93 8.2 3.3 1.3 1 1 0 1 1 1 0 Presenilin PBECR3 PF18812.1 pCP020479_00047 - 0.051 13.5 3.0 0.087 12.8 3.0 1.5 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 AAA_10 PF12846.7 pCP020479_00049 - 1.5e-05 24.1 0.1 0.0012 17.8 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.6 pCP020479_00049 - 0.17 12.2 0.9 5.2 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 pCP020479_00049 - 0.91 9.6 9.9 1 9.4 5.2 3.0 2 1 0 2 2 2 0 Helicase HerA, central domain HTH_Crp_2 PF13545.6 pCP020479_00050 - 0.0016 18.4 0.2 0.0059 16.6 0.1 2.1 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 pCP020479_00050 - 0.0078 15.8 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Phage_rep_O PF04492.13 pCP020479_00050 - 0.035 14.7 0.1 0.091 13.4 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage replication protein O Utp11 PF03998.13 pCP020479_00050 - 0.039 13.9 8.7 0.067 13.1 8.7 1.4 1 0 0 1 1 1 0 Utp11 protein DUF5359 PF17313.2 pCP020479_00050 - 0.048 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5359) DUF1413 PF07205.11 pCP020479_00050 - 0.062 13.3 1.4 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) HLH PF00010.26 pCP020479_00051 - 0.12 12.3 1.8 0.14 12.1 0.6 1.8 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain O-antigen_lig PF13425.6 pCP020479_00052 - 1.7e-06 27.1 2.5 2.1e-06 26.8 2.5 1.0 1 0 0 1 1 1 1 O-antigen ligase like membrane protein CLN3 PF02487.17 pCP020479_00052 - 0.00068 18.8 0.1 0.00074 18.7 0.1 1.1 1 0 0 1 1 1 1 CLN3 protein TMEM171 PF15471.6 pCP020479_00052 - 0.031 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Connexin PF00029.19 pCP020479_00052 - 0.061 13.1 0.4 0.089 12.5 0.4 1.2 1 0 0 1 1 1 0 Connexin DUF4834 PF16118.5 pCP020479_00052 - 0.39 11.7 9.4 2.1 9.4 9.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4355 PF14265.6 pCP020479_00052 - 0.51 10.6 11.2 0.7 10.1 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) AAA PF00004.29 pCP020479_00053 - 4.6e-15 56.2 0.0 8e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 pCP020479_00053 - 1.1e-05 25.5 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 pCP020479_00053 - 2.8e-05 24.4 0.2 0.0051 17.1 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 pCP020479_00053 - 6.1e-05 23.1 0.2 0.0002 21.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 pCP020479_00053 - 0.00029 20.1 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 pCP020479_00053 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 pCP020479_00053 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 pCP020479_00053 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2120 PF09893.9 pCP020479_00053 - 0.042 14.0 0.2 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) AAA_16 PF13191.6 pCP020479_00053 - 0.099 13.0 0.0 3.1 8.2 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain TniB PF05621.11 pCP020479_00053 - 0.19 11.1 1.1 7.9 5.8 0.1 3.0 2 1 1 3 3 3 0 Bacterial TniB protein YopX PF09643.10 pCP020479_00054 - 1.5e-12 47.7 2.9 1.9e-12 47.4 2.9 1.2 1 0 0 1 1 1 1 YopX protein Telomere_reg-2 PF10193.9 pCP020479_00056 - 0.13 12.7 0.6 5.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Telomere length regulation protein Snapin_Pallidin PF14712.6 pCP020479_00062 - 0.79 10.2 7.9 11 6.6 0.4 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Topoisom_bac PF01131.20 pCP020479_00063 - 3.7e-97 325.9 2.9 4.8e-97 325.6 2.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP020479_00063 - 1.2e-11 44.8 0.4 5.6e-11 42.6 0.1 2.4 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP020479_00063 - 2.3e-07 30.5 20.4 0.001 18.8 4.6 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP020479_00063 - 0.00043 20.5 0.2 0.69 10.2 0.0 2.4 2 0 0 2 2 2 2 zinc-ribbon Zn_ribbon_SprT PF17283.2 pCP020479_00063 - 0.015 15.2 1.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Toprim_2 PF13155.6 pCP020479_00063 - 0.054 13.9 0.2 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 Toprim-like Zn-ribbon_8 PF09723.10 pCP020479_00063 - 0.082 13.0 0.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 pCP020479_00063 - 0.1 12.5 2.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Toprim_4 PF13662.6 pCP020479_00063 - 0.1 13.1 0.1 0.68 10.4 0.0 2.4 2 0 0 2 2 2 0 Toprim domain zf-ribbon_3 PF13248.6 pCP020479_00063 - 0.18 11.3 1.0 12 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HTH_34 PF13601.6 pCP020479_00063 - 0.25 11.6 1.1 0.77 10.0 0.1 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain TRAF6_Z2 PF18048.1 pCP020479_00063 - 0.45 10.7 3.7 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS1 PF03811.13 pCP020479_00063 - 0.48 10.2 3.3 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-HIT PF04438.16 pCP020479_00063 - 0.61 10.0 4.2 5.9 6.8 0.4 2.5 2 0 0 2 2 2 0 HIT zinc finger zf_C2H2_10 PF18414.1 pCP020479_00063 - 2.6 7.7 7.4 11 5.7 1.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger PIN_4 PF13638.6 pCP020479_00063 - 4 7.7 5.5 0.89 9.8 0.5 2.4 3 0 0 3 3 3 0 PIN domain PADR1 PF08063.12 pCP020479_00063 - 7.7 6.4 8.1 9.6 6.1 1.7 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-H2C2_2 PF13465.6 pCP020479_00063 - 7.8 7.1 8.1 12 6.5 0.7 3.2 3 0 0 3 3 2 0 Zinc-finger double domain CoA_transf_3 PF02515.17 pCP020479_00064 - 0.18 10.9 0.4 0.28 10.3 0.4 1.3 1 0 0 1 1 1 0 CoA-transferase family III Tfb5 PF06331.12 pCP020479_00065 - 1.7 8.7 7.2 5.1 7.2 0.7 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 DUF3042 PF11240.8 pCP020479_00066 - 8.3 6.5 6.1 18 5.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF2368 PF10166.9 pCP020479_00067 - 0.59 9.7 2.9 0.35 10.5 1.0 1.6 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2368) Herpes_UL73 PF03554.13 pCP020479_00067 - 2.6 8.1 10.4 0.79 9.8 4.6 2.2 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein GLF PF03275.13 pCP020479_00069 - 0.021 14.5 1.0 0.021 14.5 1.0 2.2 2 1 1 3 3 3 0 UDP-galactopyranose mutase HTH_57 PF18679.1 pCP020479_00069 - 0.051 13.9 0.3 0.051 13.9 0.3 2.4 2 1 0 2 2 2 0 ThcOx helix turn helix domain DUF349 PF03993.12 pCP020479_00069 - 3.7 7.9 13.9 28 5.1 0.4 4.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF349) DUF1192 PF06698.11 pCP020479_00071 - 5.1 7.2 15.9 0.16 12.0 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Peptidase_C101 PF16218.5 pCP020479_00072 - 0.00027 20.3 6.7 0.00027 20.3 6.7 1.5 1 1 1 2 2 2 2 Peptidase family C101 HTH_45 PF14947.6 pCP020479_00072 - 0.029 14.3 1.2 0.063 13.3 1.0 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix CLAMP PF14769.6 pCP020479_00072 - 0.086 13.3 4.7 0.26 11.8 1.2 2.3 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 DUF2232 PF09991.9 pCP020479_00074 - 0.046 12.9 0.4 0.053 12.7 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Thioredoxin_2 PF13098.6 pCP020479_00075 - 5.6e-06 26.8 2.9 8.6e-06 26.2 1.5 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 pCP020479_00075 - 0.00015 22.0 2.1 0.0006 20.0 0.2 2.3 2 0 0 2 2 2 1 Thioredoxin Glutaredoxin PF00462.24 pCP020479_00075 - 0.0022 18.2 0.3 0.0094 16.2 0.3 2.0 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 pCP020479_00075 - 0.0074 16.3 0.1 0.055 13.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain HypD PF01924.16 pCP020479_00075 - 0.061 12.4 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Aminopep PF10023.9 pCP020479_00075 - 3.2 7.0 7.8 0.56 9.5 1.4 2.1 1 1 1 2 2 2 0 Putative aminopeptidase 4HFCP_synth PF04476.13 pCP020479_00077 - 0.005 16.6 0.1 0.0092 15.7 0.1 1.4 1 0 0 1 1 1 1 4-HFC-P synthase Herpes_U30 PF04523.13 pCP020479_00077 - 0.044 11.7 3.7 0.051 11.5 3.7 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 TT_ORF1 PF02956.14 pCP020479_00077 - 0.14 10.8 2.1 0.14 10.8 2.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF4776 PF16003.5 pCP020479_00077 - 3.4 6.6 9.6 3.8 6.4 9.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4776) LMBR1 PF04791.16 pCP020479_00077 - 4.3 6.1 6.3 4.7 6.0 6.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Bacillus_HBL PF05791.11 pCP020479_00078 - 0.03 14.2 1.8 0.04 13.8 1.8 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Tape_meas_lam_C PF09718.10 pCP020479_00078 - 0.035 14.2 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Prefoldin_3 PF13758.6 pCP020479_00078 - 0.042 13.9 1.1 0.055 13.5 1.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit Erf4 PF10256.9 pCP020479_00078 - 0.09 12.9 0.9 1.1 9.4 0.5 2.3 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family KAR PF15222.6 pCP020479_00080 - 0.037 14.3 2.6 2 8.8 0.5 2.1 2 0 0 2 2 2 0 Kidney androgen-regulated LRAT PF04970.13 pCP020479_00081 - 0.035 14.4 0.0 0.037 14.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin retinol acyltransferase SNase PF00565.17 pCP020479_00082 - 2.2e-26 92.4 0.3 3.2e-26 91.9 0.3 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue HipA_C PF07804.12 pCP020479_00084 - 1.5e-07 31.3 0.2 6e-07 29.4 0.2 2.0 1 1 0 1 1 1 1 HipA-like C-terminal domain PI3_PI4_kinase PF00454.27 pCP020479_00084 - 0.17 11.7 2.3 0.43 10.3 2.3 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase DUF751 PF05421.11 pCP020479_00085 - 0.0064 17.2 1.2 0.0099 16.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF751) ThrE PF06738.12 pCP020479_00085 - 0.012 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter Tom22 PF04281.13 pCP020479_00085 - 0.046 13.5 0.1 0.067 13.0 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Cadherin_C_2 PF16492.5 pCP020479_00086 - 0.11 13.3 0.0 0.11 13.3 0.0 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal RSN1_TM PF13967.6 pCP020479_00088 - 0.039 13.7 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Chordopox_A13L PF05961.11 pCP020479_00088 - 0.1 12.8 0.6 0.13 12.5 0.6 1.2 1 1 0 1 1 1 0 Chordopoxvirus A13L protein HipA_C PF07804.12 pCP020479_00089 - 2.2e-32 112.5 0.3 3.7e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 HipA-like C-terminal domain Fic PF02661.18 pCP020479_00090 - 1.1e-18 67.9 0.7 2.1e-18 67.0 0.1 1.8 2 0 0 2 2 2 1 Fic/DOC family NPV_P10 PF05531.12 pCP020479_00091 - 0.034 14.6 0.3 0.046 14.2 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1246 PF06849.12 pCP020479_00091 - 0.092 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) DivIC PF04977.15 pCP020479_00091 - 0.1 12.4 1.7 0.14 11.9 1.7 1.4 1 1 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 pCP020479_00091 - 0.25 11.6 7.0 0.37 11.0 2.7 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper TraG-D_C PF12696.7 pCP020479_00092 - 4.2e-10 39.7 0.1 9.7e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP020479_00092 - 5.1e-06 25.7 0.3 0.01 14.8 0.1 2.7 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP020479_00092 - 6.5e-06 26.4 0.2 1.7e-05 25.0 0.2 1.8 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_10 PF12846.7 pCP020479_00092 - 9.1e-06 24.8 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain DUF853 PF05872.12 pCP020479_00092 - 0.0066 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) PAPS_reduct PF01507.19 pCP020479_00092 - 0.02 14.9 0.1 0.049 13.7 0.1 1.6 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family CSM2 PF16834.5 pCP020479_00093 - 0.031 13.9 1.4 0.037 13.7 0.2 1.7 2 0 0 2 2 2 0 Shu complex component Csm2, DNA-binding Ribonuc_red_lgC PF02867.15 pCP020479_00093 - 0.057 11.9 0.5 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Ribonucleotide reductase, barrel domain eIF-5_eIF-2B PF01873.17 pCP020479_00093 - 0.17 11.7 2.0 0.15 12.0 0.5 1.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RHH_7 PF16777.5 pCP020480_00001 - 0.11 12.9 6.6 0.32 11.4 2.2 2.5 1 1 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG TMEM95 PF15203.6 pCP020480_00001 - 0.12 12.0 2.6 0.099 12.3 0.5 1.8 2 0 0 2 2 2 0 TMEM95 family pRN1_helical PF13010.6 pCP020480_00001 - 3.7 7.5 9.1 2.4 8.1 6.5 1.9 1 1 1 2 2 2 0 Primase helical domain Relaxase PF03432.14 pCP020480_00002 - 4.2e-07 29.8 1.0 4.2e-07 29.8 1.0 2.8 2 1 1 3 3 3 1 Relaxase/Mobilisation nuclease domain DUF1673 PF07895.11 pCP020480_00003 - 0.0051 16.5 3.4 0.0051 16.5 3.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1673) DUF782 PF05614.11 pCP020480_00003 - 0.0068 16.8 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 Circovirus protein of unknown function (DUF782) MCU PF04678.13 pCP020480_00003 - 0.047 13.8 0.3 0.07 13.2 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Acyl_transf_3 PF01757.22 pCP020480_00003 - 0.074 12.1 5.8 0.16 11.0 6.0 1.4 1 1 0 1 1 1 0 Acyltransferase family Adeno_terminal PF02459.15 pCP020480_00003 - 0.097 11.0 0.5 0.11 10.9 0.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF2663 PF10864.8 pCP020480_00003 - 0.14 12.6 12.1 0.54 10.7 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Sugarporin_N PF11471.8 pCP020480_00003 - 0.15 12.0 0.2 0.72 9.9 0.1 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF3611 PF12263.8 pCP020480_00003 - 0.46 10.4 6.6 0.28 11.1 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) ECF_trnsprt PF12822.7 pCP020480_00003 - 2 8.5 8.7 13 5.9 2.0 2.1 1 1 0 2 2 2 0 ECF transporter, substrate-specific component E1-E2_ATPase PF00122.20 pCP020480_00003 - 3.6 7.1 4.3 7.4 6.1 0.5 2.6 1 1 2 3 3 3 0 E1-E2 ATPase Bac_export_2 PF01312.19 pCP020480_00003 - 3.9 6.6 6.8 0.69 9.1 1.0 1.9 1 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family DHHC PF01529.20 pCP020480_00004 - 3.4 7.8 8.5 1.8 8.7 2.9 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase AAA_31 PF13614.6 pCP020480_00008 - 1.9e-11 44.2 4.9 6.7e-11 42.4 2.8 2.6 1 1 1 2 2 2 1 AAA domain MipZ PF09140.11 pCP020480_00008 - 2.6e-11 43.3 1.7 3.3e-06 26.6 1.0 3.1 1 1 1 2 2 2 2 ATPase MipZ CbiA PF01656.23 pCP020480_00008 - 4.3e-09 36.5 0.1 6.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 pCP020480_00008 - 0.00014 21.2 0.4 0.00081 18.7 0.0 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 pCP020480_00008 - 0.0011 18.3 0.1 0.85 8.9 0.0 2.1 2 0 0 2 2 2 2 VirC1 protein ABC2_membrane_3 PF12698.7 pCP020480_00008 - 0.0019 17.4 0.9 0.0021 17.2 0.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_24 PF13479.6 pCP020480_00008 - 0.0035 17.1 1.2 0.0061 16.3 0.1 1.8 2 1 0 2 2 2 1 AAA domain ParA PF10609.9 pCP020480_00008 - 0.004 16.7 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ATP_bind_1 PF03029.17 pCP020480_00008 - 0.019 14.8 0.1 0.068 13.0 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CBP_BcsQ PF06564.12 pCP020480_00008 - 0.14 11.6 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ DUF2139 PF09910.9 pCP020480_00008 - 0.14 11.3 0.0 0.45 9.6 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) AAA_14 PF13173.6 pCP020480_00008 - 0.19 11.7 7.5 0.051 13.6 1.4 2.6 1 1 2 3 3 3 0 AAA domain Fic PF02661.18 pCP020480_00009 - 3.2e-15 56.8 0.1 7.3e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Fic/DOC family IL22 PF14565.6 pCP020480_00009 - 0.018 15.3 0.9 1.5 9.1 0.0 2.8 2 1 1 3 3 3 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor IZUMO PF15005.6 pCP020480_00009 - 1.1 9.8 7.3 1.7 9.2 0.1 2.9 2 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated CRISPR_Cas2 PF09827.9 pCP020480_00011 - 0.00069 19.8 1.5 0.0022 18.1 0.0 2.3 1 1 1 2 2 2 1 CRISPR associated protein Cas2 RRM_1 PF00076.22 pCP020480_00011 - 0.0021 17.8 0.5 0.0083 15.9 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPD11 PF18824.1 pCP020480_00011 - 0.085 12.9 1.8 0.17 12.0 0.4 2.2 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 YopX PF09643.10 pCP020480_00013 - 1.4e-08 34.8 0.5 1.4e-08 34.8 0.5 2.2 1 1 1 2 2 2 1 YopX protein Topoisom_bac PF01131.20 pCP020480_00014 - 3.8e-97 325.9 2.9 4.8e-97 325.6 2.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP020480_00014 - 6.8e-12 45.5 0.3 3.4e-11 43.3 0.1 2.4 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP020480_00014 - 2.3e-07 30.5 20.4 0.001 18.8 4.6 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP020480_00014 - 0.00043 20.5 0.2 0.69 10.2 0.0 2.4 2 0 0 2 2 2 2 zinc-ribbon Zn_ribbon_SprT PF17283.2 pCP020480_00014 - 0.014 15.2 1.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Toprim_2 PF13155.6 pCP020480_00014 - 0.034 14.6 0.2 0.68 10.4 0.1 2.6 2 0 0 2 2 2 0 Toprim-like Zn-ribbon_8 PF09723.10 pCP020480_00014 - 0.082 13.0 0.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 pCP020480_00014 - 0.1 12.5 2.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Toprim_4 PF13662.6 pCP020480_00014 - 0.12 12.8 0.1 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 Toprim domain zf-ribbon_3 PF13248.6 pCP020480_00014 - 0.18 11.3 1.0 12 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain HTH_34 PF13601.6 pCP020480_00014 - 0.25 11.6 1.1 0.77 10.0 0.1 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain TRAF6_Z2 PF18048.1 pCP020480_00014 - 0.45 10.6 3.7 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS1 PF03811.13 pCP020480_00014 - 0.48 10.2 3.3 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-HIT PF04438.16 pCP020480_00014 - 0.61 10.0 4.2 5.9 6.8 0.4 2.5 2 0 0 2 2 2 0 HIT zinc finger zf_C2H2_10 PF18414.1 pCP020480_00014 - 2.6 7.7 7.4 11 5.7 1.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger PIN_4 PF13638.6 pCP020480_00014 - 4.1 7.7 5.5 0.89 9.8 0.5 2.4 3 0 0 3 3 3 0 PIN domain PADR1 PF08063.12 pCP020480_00014 - 7.6 6.4 8.1 9.6 6.1 1.7 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-H2C2_2 PF13465.6 pCP020480_00014 - 7.9 7.1 8.1 12 6.5 0.7 3.2 3 0 0 3 3 2 0 Zinc-finger double domain Latarcin PF10279.9 pCP020480_00016 - 0.016 15.6 1.6 0.66 10.4 1.6 3.5 1 1 0 1 1 1 0 Latarcin precursor Lipase_GDSL PF00657.22 pCP020480_00016 - 0.033 14.2 1.1 0.067 13.2 0.9 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase T3SS_basalb_I PF17001.5 pCP020480_00016 - 0.078 13.6 4.2 1.7 9.3 0.5 2.8 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cor1 PF04803.12 pCP020480_00016 - 0.15 12.3 22.3 0.15 12.2 6.2 3.3 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1451 PF07295.11 pCP020480_00016 - 0.25 11.3 8.8 0.2 11.7 2.5 2.5 1 1 2 3 3 3 0 Zinc-ribbon containing domain TipAS PF07739.13 pCP020480_00016 - 0.36 11.4 6.4 9 6.9 0.2 3.3 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Exonuc_VII_L PF02601.15 pCP020480_00016 - 0.37 10.3 10.9 0.65 9.5 2.7 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.14 pCP020480_00016 - 2.8 8.3 16.8 3.5 8.0 3.1 2.8 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) TrbM PF07424.11 pCP020480_00017 - 3.4e-39 134.3 1.4 4.3e-39 133.9 1.4 1.1 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP020480_00018 - 1.1e-16 61.2 0.1 1.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 LPAM_2 PF13627.6 pCP020480_00018 - 0.027 14.3 3.2 0.044 13.6 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF5061 PF16587.5 pCP020480_00018 - 0.15 12.2 0.1 0.19 11.8 0.1 1.3 1 1 0 1 1 1 0 17 kDa common-antigen outer membrane protein T4SS-DNA_transf PF02534.14 pCP020480_00019 - 1.1e-109 367.3 0.1 1.5e-109 366.9 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP020480_00019 - 6.2e-27 94.1 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP020480_00019 - 1.4e-18 67.0 0.0 3.3e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain BRI3BP PF14965.6 pCP020480_00019 - 0.1 12.1 2.6 0.11 12.0 1.5 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Njmu-R1 PF15053.6 pCP020480_00021 - 0.0055 15.9 1.7 0.0081 15.3 1.7 1.3 1 0 0 1 1 1 1 Mjmu-R1-like protein family SlyX PF04102.12 pCP020480_00021 - 0.5 11.0 6.8 1.7 9.3 0.9 2.4 2 0 0 2 2 2 0 SlyX PEP-utilisers_N PF05524.13 pCP020480_00021 - 0.54 10.5 3.9 7.8 6.7 0.3 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Halogen_Hydrol PF10112.9 pCP020480_00021 - 1.6 8.8 7.3 9.1 6.3 0.9 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF16 PF01519.16 pCP020480_00021 - 4.3 7.9 11.6 3.2 8.3 2.4 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 PCRF PF03462.18 pCP020480_00021 - 4.3 7.1 17.6 0.53 10.1 5.0 2.9 2 1 0 2 2 2 0 PCRF domain T2SSE PF00437.20 pCP020480_00022 - 5.1e-54 183.2 0.0 6.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 pCP020480_00022 - 4.9e-05 23.6 0.0 9.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pCP020480_00022 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP020480_00022 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP020480_00022 - 0.00062 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 pCP020480_00022 - 0.0028 18.2 1.3 0.0028 18.2 1.3 1.9 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 pCP020480_00022 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 pCP020480_00022 - 0.003 17.0 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_15 PF13175.6 pCP020480_00022 - 0.0035 17.1 2.5 0.0035 17.1 2.5 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 pCP020480_00022 - 0.0041 16.9 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 pCP020480_00022 - 0.0043 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.22 pCP020480_00022 - 0.012 16.0 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 pCP020480_00022 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 pCP020480_00022 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 pCP020480_00022 - 0.015 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 pCP020480_00022 - 0.015 15.4 1.0 0.03 14.4 0.2 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 pCP020480_00022 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 pCP020480_00022 - 0.021 14.6 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 pCP020480_00022 - 0.023 14.1 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 pCP020480_00022 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 pCP020480_00022 - 0.045 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 pCP020480_00022 - 0.046 12.6 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 pCP020480_00022 - 0.051 13.6 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.15 pCP020480_00022 - 0.055 13.5 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SMC_N PF02463.19 pCP020480_00022 - 0.063 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 pCP020480_00022 - 0.07 12.9 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 pCP020480_00022 - 0.073 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 pCP020480_00022 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 pCP020480_00022 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 pCP020480_00022 - 0.091 12.8 0.3 0.21 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain GvpD PF07088.11 pCP020480_00022 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 pCP020480_00022 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 pCP020480_00022 - 0.12 12.6 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 pCP020480_00022 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MORN_2 PF07661.13 pCP020480_00023 - 0.39 11.1 2.9 2.8 8.4 0.6 2.8 2 0 0 2 2 2 0 MORN repeat variant Ribosomal_S13 PF00416.22 pCP020480_00023 - 0.83 10.1 4.2 17 5.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S13/S18 TrbI PF03743.14 pCP020480_00024 - 2.2e-47 161.4 0.1 2.5e-47 161.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein DUF5345 PF17280.2 pCP020480_00025 - 0.01 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF3671 PF12420.8 pCP020480_00025 - 0.029 14.4 0.2 0.036 14.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function Cyt_bd_oxida_I PF01654.17 pCP020480_00025 - 0.074 11.7 0.0 0.079 11.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I PAP_PilO PF06864.12 pCP020480_00025 - 0.12 11.2 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) AIF_C PF14721.6 pCP020480_00025 - 0.19 12.1 2.0 0.23 11.8 0.4 1.8 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Vpu PF00558.19 pCP020480_00025 - 1.5 8.7 5.5 5.1 6.9 5.4 1.8 1 1 0 1 1 1 0 Vpu protein CagX PF03524.15 pCP020480_00026 - 7.1e-54 182.7 0.7 1.4e-53 181.7 0.7 1.5 1 1 0 1 1 1 1 Conjugal transfer protein VirB8 PF04335.13 pCP020480_00027 - 8.4e-50 169.6 0.1 1e-49 169.3 0.1 1.0 1 0 0 1 1 1 1 VirB8 protein Wzz PF02706.15 pCP020480_00027 - 2.4 8.5 6.7 2.8 8.3 3.2 2.5 2 1 0 2 2 2 0 Chain length determinant protein VASP_tetra PF08776.11 pCP020480_00028 - 0.063 12.9 6.4 0.16 11.5 6.4 1.7 1 0 0 1 1 1 0 VASP tetramerisation domain TrbL PF04610.14 pCP020480_00030 - 1.2e-32 113.5 25.3 1.6e-32 113.0 25.3 1.3 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein DUF2070 PF09843.9 pCP020480_00030 - 0.45 8.7 16.6 0.69 8.1 16.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AIM3 PF17096.5 pCP020480_00030 - 5.4 8.0 7.0 9.6 7.2 7.0 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF412 PF04217.13 pCP020480_00030 - 5.6 6.9 10.8 17 5.3 6.6 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF412 T4SS PF07996.11 pCP020480_00031 - 2e-23 83.9 15.9 2.4e-23 83.6 15.9 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins CHASE4 PF05228.13 pCP020480_00031 - 0.051 13.8 5.7 1 9.6 0.2 2.8 2 1 1 3 3 3 0 CHASE4 domain AChE_tetra PF08674.10 pCP020480_00031 - 0.096 12.4 1.2 0.5 10.1 0.1 2.3 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain zf-RING_6 PF14835.6 pCP020480_00031 - 0.12 12.2 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein KMP11 PF03037.16 pCP020480_00031 - 0.13 13.1 3.2 0.31 11.8 0.0 2.9 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 PCRF PF03462.18 pCP020480_00031 - 0.22 11.3 12.0 2.7 7.8 0.4 2.2 2 0 0 2 2 2 0 PCRF domain Med8 PF10232.9 pCP020480_00031 - 0.27 10.8 9.0 0.027 14.1 3.9 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1474 PF07342.11 pCP020480_00031 - 1.3 9.5 5.1 0.42 11.2 1.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1474) Phage_pRha PF09669.10 pCP020480_00032 - 1.4e-29 102.4 0.0 2.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) CagE_TrbE_VirB PF03135.14 pCP020480_00033 - 2.5e-43 148.6 0.5 6.2e-43 147.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP020480_00033 - 1.2e-19 70.3 2.0 2.1e-19 69.5 2.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 pCP020480_00034 - 2.3e-16 59.8 8.3 2.5e-16 59.7 8.3 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family ThrE PF06738.12 pCP020480_00034 - 0.025 14.0 2.1 0.029 13.8 2.1 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF2062 PF09835.9 pCP020480_00034 - 1.4 8.7 7.8 2 8.3 7.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP020480_00036 - 0.0005 20.2 1.3 0.00061 19.9 0.1 1.7 2 0 0 2 2 2 1 CRISPR associated protein Cas2 Resolvase PF00239.21 pCP020480_00037 - 1e-32 113.2 0.6 1.3e-32 112.9 0.6 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP020480_00037 - 0.0011 18.6 1.4 0.12 12.1 0.1 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain Mu-like_Pro PF10123.9 pCP020480_00037 - 0.12 11.9 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Pox_A_type_inc PF04508.12 pCP020480_00037 - 8.5 6.4 9.6 0.19 11.6 0.8 3.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SseC PF04888.12 pCP020480_00038 - 0.0012 18.6 1.4 0.0012 18.6 1.4 1.8 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Leu_Phe_trans PF03588.14 pCP020480_00038 - 0.034 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase T2SSF PF00482.23 pCP020480_00038 - 0.18 11.8 0.1 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3185 PF11381.8 pCP020480_00038 - 0.19 11.7 9.4 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2207 PF09972.9 pCP020480_00038 - 6.4 5.4 16.4 0.089 11.5 1.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) AAA_25 PF13481.6 pCP020480_00039 - 6.7e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP020480_00039 - 0.00036 20.0 0.0 0.0021 17.4 0.0 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP020480_00039 - 0.0014 18.4 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP020480_00039 - 0.012 15.0 0.0 0.044 13.1 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA PF00004.29 pCP020480_00039 - 0.076 13.4 0.3 0.89 10.0 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP020480_00039 - 0.19 11.8 2.8 1.7 8.7 2.8 2.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Toprim_3 PF13362.6 pCP020480_00040 - 4.6e-09 36.5 0.0 7.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pCP020480_00040 - 0.001 19.5 0.1 0.0023 18.4 0.1 1.5 1 0 0 1 1 1 1 Toprim domain Fic PF02661.18 pCP020480_00041 - 3.3e-17 63.2 0.1 9.2e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family MAS20 PF02064.15 pCP020480_00042 - 0.22 11.6 7.6 0.28 11.3 0.1 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor ANAPC4 PF12896.7 pCP020480_00043 - 0.027 14.0 0.1 0.034 13.6 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 MSG PF02349.15 pCP020480_00043 - 0.071 13.3 4.6 0.094 12.9 4.6 1.2 1 0 0 1 1 1 0 Major surface glycoprotein EssA PF10661.9 pCP020480_00044 - 0.18 11.6 8.8 0.16 11.8 7.9 1.3 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA GTP_EFTU PF00009.27 pCP020775_00001 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP020775_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP020775_00001 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP020775_00001 - 3e-12 46.4 0.1 6.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP020775_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP020775_00001 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP020775_00001 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP020775_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP020775_00001 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 pCP020775_00002 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP020775_00002 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP020775_00002 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 pCP020775_00003 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pCP020775_00004 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP020775_00004 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 pCP020775_00005 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP020775_00005 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP020775_00005 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pCP020775_00005 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pCP020775_00005 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pCP020775_00005 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pCP020775_00005 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP020775_00005 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pCP020775_00005 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pCP020775_00006 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP020775_00006 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP020775_00006 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP020775_00006 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP020775_00006 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP020775_00007 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP020775_00007 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP020775_00008 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP020775_00008 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP020775_00008 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP020775_00008 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP020775_00008 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP020775_00009 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP020775_00010 - 3e-16 59.1 2.6 4.1e-16 58.6 0.1 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP020775_00010 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP020775_00010 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP020775_00010 - 8.9e-06 25.6 1.8 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP020775_00010 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pCP020775_00011 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pCP020775_00011 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pCP020775_00011 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pCP020775_00012 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP020775_00012 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pCP020775_00012 - 0.0083 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 pCP020775_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP020775_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP020775_00014 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP020775_00014 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP020775_00014 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP020775_00014 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pCP020775_00015 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pCP020775_00015 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pCP020775_00015 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pCP020775_00017 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP020775_00018 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP020775_00018 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP020775_00018 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP020775_00018 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP020775_00019 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pCP020775_00020 - 0.0019 18.2 0.5 0.0023 18.0 0.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pCP020775_00020 - 0.14 12.5 3.0 0.19 12.1 3.0 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pCP020775_00020 - 1.1 9.2 4.2 2 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP020775_00022 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system AAA_25 PF13481.6 pCP020775_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP020775_00023 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP020775_00023 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP020775_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP020775_00023 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP020775_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP020775_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pCP020775_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP020775_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP020775_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP020775_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP020775_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP020775_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP020775_00027 - 3.4e-11 43.2 3.7 4e-11 43.0 3.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP020775_00027 - 0.12 12.2 4.4 0.18 11.6 4.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP020775_00028 - 1.7e-50 172.0 0.4 3.9e-50 170.8 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP020775_00028 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP020775_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP020775_00029 - 6.6e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP020775_00029 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 pCP020775_00029 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) FapA PF03961.13 pCP020775_00030 - 0.0039 15.9 6.9 0.0039 15.9 6.9 1.6 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 pCP020775_00030 - 0.028 14.3 4.0 0.028 14.3 4.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Fib_alpha PF08702.10 pCP020775_00030 - 0.6 10.3 12.2 0.061 13.5 4.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 pCP020775_00030 - 1.7 8.4 11.6 0.92 9.3 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator Striatin PF08232.12 pCP020775_00030 - 4.6 7.8 9.6 14 6.2 9.6 1.9 1 1 0 1 1 1 0 Striatin family Syntaxin-6_N PF09177.11 pCP020775_00030 - 9.3 6.9 10.2 1.8 9.2 4.5 2.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal SSB PF00436.25 pCP020775_00032 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP020775_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP020775_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP020775_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP020775_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP020775_00034 - 8.6e-29 101.4 13.7 1.2e-28 100.9 13.7 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP020775_00034 - 0.006 16.7 1.1 0.021 15.0 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pCP020775_00034 - 0.018 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pCP020775_00034 - 0.041 14.6 11.0 0.031 15.0 4.9 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3752 PF12572.8 pCP020775_00034 - 1.4 9.5 6.4 9.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) THOC7 PF05615.13 pCP020775_00034 - 2.8 8.2 12.1 1.7 9.0 0.2 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 Snapin_Pallidin PF14712.6 pCP020775_00034 - 4.8 7.7 10.3 1.9 8.9 5.5 2.7 2 1 0 2 2 2 0 Snapin/Pallidin TrbL PF04610.14 pCP020775_00035 - 3.3e-29 102.2 32.7 3.3e-29 102.2 32.7 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP020775_00035 - 0.087 12.6 1.7 0.49 10.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP020775_00035 - 1.7 9.6 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP020775_00036 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP020775_00036 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP020775_00037 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP020775_00037 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP020775_00038 - 9.4e-56 188.9 1.6 1.6e-55 188.2 1.6 1.3 1 1 0 1 1 1 1 Conjugal transfer protein Rho_RNA_bind PF07497.12 pCP020775_00038 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pCP020775_00039 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP020775_00039 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP020775_00040 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP020775_00040 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP020775_00040 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP020775_00040 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP020775_00040 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP020775_00040 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pCP020775_00040 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pCP020775_00040 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP020775_00040 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP020775_00040 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP020775_00040 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP020775_00040 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pCP020775_00040 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 pCP020775_00040 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 pCP020775_00040 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 pCP020775_00040 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 pCP020775_00040 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 pCP020775_00040 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pCP020775_00040 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 pCP020775_00040 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pCP020775_00040 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pCP020775_00040 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP020775_00040 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP020775_00040 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP020775_00040 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP020775_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP020775_00040 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP020775_00040 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP020775_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP020775_00040 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP020775_00040 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP020775_00041 - 8.4e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP020775_00041 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP020775_00041 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pCP020775_00041 - 0.19 11.8 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 pCP020775_00042 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP020775_00042 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pCP020775_00043 - 2.4e-38 131.5 1.9 3.1e-38 131.2 1.9 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 pCP020775_00043 - 0.21 10.6 0.1 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal PRELI PF04707.14 pCP020775_00044 - 0.041 13.7 0.4 0.041 13.7 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Rsd_AlgQ PF04353.13 pCP020775_00044 - 0.82 9.6 6.3 0.24 11.4 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ KH_5 PF13184.6 pCP020775_00045 - 0.00035 20.6 0.5 0.00039 20.5 0.5 1.0 1 0 0 1 1 1 1 NusA-like KH domain CdhD PF03599.16 pCP020775_00046 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 pCP020775_00046 - 0.028 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 pCP020775_00046 - 0.12 12.6 0.1 0.12 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized YnfE-like DUF1461 PF07314.11 pCP020775_00047 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pCP020775_00048 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP020775_00048 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP020775_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP020775_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP020775_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP020775_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP020775_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP020775_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP020775_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP020775_00048 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP020775_00048 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP020775_00048 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP020775_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP020775_00048 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP020775_00048 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP020775_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP020775_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP020775_00049 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP020775_00049 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain HicB_lk_antitox PF15919.5 pCP022078_00002 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pCP022078_00002 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 pCP022078_00003 - 1.7e-15 57.1 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP022078_00003 - 0.00083 18.8 0.0 0.0041 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP022078_00003 - 0.0013 18.5 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pCP022078_00003 - 0.003 17.3 1.1 0.009 15.7 0.2 2.1 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 pCP022078_00003 - 0.009 15.4 0.0 0.062 12.6 0.0 2.5 2 1 0 2 2 2 1 KaiC CbiA PF01656.23 pCP022078_00003 - 0.19 11.8 1.3 0.63 10.1 1.3 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pCP022078_00004 - 0.012 15.5 0.4 0.02 14.7 0.4 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pCP022078_00006 - 2.4e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP022078_00006 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP022078_00006 - 0.051 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP022078_00006 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP022078_00007 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP022078_00007 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP022078_00009 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP022078_00009 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP022078_00010 - 7.6e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP022078_00010 - 1.5e-20 73.2 1.0 2.6e-20 72.4 1.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pCP022078_00010 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pCP022078_00010 - 0.038 14.1 5.5 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pCP022078_00011 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pCP022078_00011 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pCP022078_00011 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pCP022078_00011 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pCP022078_00011 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 pCP022078_00012 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 pCP022078_00013 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP022078_00014 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP022078_00014 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP022078_00014 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP022078_00014 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP022078_00015 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP022078_00015 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP022078_00015 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP022078_00015 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP022078_00015 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 pCP022078_00015 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 pCP022078_00015 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pCP022078_00015 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pCP022078_00016 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP022078_00016 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP022078_00016 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP022078_00017 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP022078_00017 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP022078_00018 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP022078_00018 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP022078_00019 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP022078_00019 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP022078_00020 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP022078_00020 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP022078_00021 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP022078_00021 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP022078_00021 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP022078_00021 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP022078_00021 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP022078_00021 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP022078_00021 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP022078_00021 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP022078_00021 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP022078_00021 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP022078_00021 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP022078_00021 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP022078_00021 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP022078_00021 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP022078_00021 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP022078_00021 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP022078_00021 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP022078_00021 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP022078_00021 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP022078_00021 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP022078_00021 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP022078_00021 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP022078_00021 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP022078_00021 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP022078_00021 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP022078_00021 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP022078_00021 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP022078_00021 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP022078_00021 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP022078_00021 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP022078_00021 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP022078_00022 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP022078_00022 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP022078_00022 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP022078_00022 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP022078_00023 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP022078_00023 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP022078_00023 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP022078_00023 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP022078_00024 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP022078_00025 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP022078_00025 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP022078_00025 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP022078_00027 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP022078_00028 - 1.4e-97 327.4 8.2 1.9e-97 326.9 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP022078_00028 - 3.7e-12 46.4 2.7 5.7e-12 45.8 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP022078_00028 - 0.05 13.4 2.1 0.14 12.0 2.1 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP022078_00028 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon EF-hand_8 PF13833.6 pCP022078_00028 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pCP022078_00028 - 0.34 11.1 3.3 0.78 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pCP022078_00029 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP022078_00029 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP022078_00031 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP022078_00031 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP022078_00031 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP022078_00031 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP022078_00031 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP022078_00031 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP022078_00031 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP022078_00031 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP022078_00031 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF5442 PF17514.2 pCP022078_00032 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pCP022078_00034 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP022078_00034 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pCP022078_00035 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP022078_00035 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP022078_00036 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pCP022078_00037 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP022078_00037 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP022078_00037 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP022078_00037 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP022078_00037 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP022078_00037 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP022078_00037 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pCP022078_00038 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP022078_00038 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP022078_00038 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP022078_00038 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP022078_00038 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP022078_00039 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP022078_00039 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP022078_00040 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP022078_00040 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP022078_00040 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP022078_00040 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP022078_00040 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP022078_00041 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP022078_00042 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP022078_00042 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP022078_00042 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP022078_00042 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP022078_00042 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pCP022078_00043 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP022078_00043 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pCP022078_00044 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP022078_00045 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP022078_00045 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP022078_00045 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP022078_00045 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP022078_00045 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pCP022078_00046 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pCP022078_00046 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pCP022078_00046 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pCP022078_00049 - 2.4e-08 34.2 0.1 6.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pCP022078_00049 - 0.016 15.4 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein 5_3_exonuc PF01367.20 pCP022078_00049 - 0.33 11.6 2.5 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP022078_00050 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pCP022078_00050 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 pCP022078_00051 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 pCP022078_00052 - 4.3e-19 68.9 4.7 4.9e-19 68.7 4.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pCP022078_00052 - 3.7e-18 65.8 0.5 3.7e-18 65.8 0.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pCP022078_00052 - 1.3e-06 27.4 0.6 1.7e-06 27.1 0.6 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 pCP022078_00052 - 0.072 12.4 0.0 0.21 10.9 0.0 1.7 1 1 1 2 2 2 0 Kinase-like W2 PF02020.18 pCP022471_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP022471_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pCP022471_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP022471_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP022471_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pCP022471_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP022471_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP022471_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP022471_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP022471_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP022471_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP022471_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pCP022471_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP022471_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP022471_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP022471_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP022471_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP022471_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP022471_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP022471_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP022471_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP022471_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP022471_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP022471_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP022471_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pCP022471_00009 - 1.6e-16 60.0 0.9 4.1e-16 58.6 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP022471_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP022471_00009 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP022471_00009 - 7.8e-06 25.8 1.5 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP022471_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pCP022471_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP022471_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pCP022471_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP022471_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP022471_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pCP022471_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pCP022471_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pCP022471_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE ESP PF16590.5 pCP022471_00013 - 0.55 10.5 4.6 0.27 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pCP022471_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pCP022471_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP022471_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP022471_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP022471_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP022471_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pCP022471_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pCP022471_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pCP022471_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pCP022471_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pCP022471_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pCP022471_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pCP022471_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP022471_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP022471_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP022471_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP022471_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP022471_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pCP022471_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pCP022471_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pCP022471_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pCP022471_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pCP022471_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP022471_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP022471_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pCP022471_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pCP022471_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pCP022471_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pCP022471_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP022471_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP022471_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP022471_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pCP022471_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pCP022471_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pCP022471_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pCP022471_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pCP022471_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pCP022471_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pCP022471_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pCP022471_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pCP022471_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP022471_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP022471_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pCP022471_00033 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP022471_00033 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pCP022471_00033 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pCP022471_00033 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pCP022471_00033 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pCP022471_00033 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pCP022471_00033 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pCP022471_00033 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pCP022471_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP022471_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pCP022471_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pCP022471_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pCP022471_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pCP022471_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP022471_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP022471_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pCP022471_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pCP022471_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP022471_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP022471_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP022471_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP022471_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP022471_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP022471_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP022471_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP022471_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pCP022471_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP022471_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP022471_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP022471_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP022471_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pCP022471_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pCP022471_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pCP022471_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pCP022471_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pCP022471_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pCP022471_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pCP022471_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pCP022471_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pCP022471_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pCP022471_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP022471_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP022471_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP022471_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pCP022471_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pCP022471_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pCP022471_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pCP022471_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP022471_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP022471_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pCP022471_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP022471_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP022471_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pCP022471_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pCP022471_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pCP022471_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pCP022471_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pCP022471_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pCP022471_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP022471_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pCP022471_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pCP022471_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pCP022471_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pCP022471_00046 - 5.7e-97 325.3 8.0 8e-97 324.8 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP022471_00046 - 5.5e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP022471_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP022471_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP022471_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP022471_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP022471_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP022471_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP022471_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP022471_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP022471_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP022471_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP022471_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP022471_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP022471_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP022471_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP022471_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP022471_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP022471_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pCP022471_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP022471_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP022471_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP022471_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP022471_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP022471_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP022471_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP022471_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP022471_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pCP022471_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pCP022471_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) PDDEXK_4 PF14281.6 pCP023447_00001 - 3e-38 131.8 13.1 3e-38 131.8 13.1 2.8 3 0 0 3 3 3 2 PD-(D/E)XK nuclease superfamily Eco57I PF07669.11 pCP023447_00002 - 2.1e-19 70.0 0.1 1.2e-18 67.5 0.1 2.4 1 0 0 1 1 1 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 pCP023447_00002 - 1.8e-12 47.4 1.7 1.8e-12 47.4 1.7 3.9 4 1 0 4 4 4 1 TaqI-like C-terminal specificity domain Mrr_cat PF04471.12 pCP023447_00002 - 0.018 15.1 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Restriction endonuclease ACP_PD PF04336.12 pCP023447_00002 - 0.019 15.4 0.2 1.2 9.6 0.1 3.6 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase DUF4756 PF15948.5 pCP023447_00002 - 0.41 10.5 7.1 0.089 12.6 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) Pentapeptide_3 PF13576.6 pCP023447_00003 - 6.7e-11 42.2 11.9 4.9e-09 36.2 2.3 5.6 4 2 1 5 5 5 3 Pentapeptide repeats (9 copies) SIMPL PF04402.14 pCP023447_00004 - 3.7e-14 53.7 0.6 4.5e-14 53.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF4116 PF13475.6 pCP023447_00004 - 0.036 13.8 1.6 0.036 13.8 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) ATR13 PF16829.5 pCP023447_00004 - 0.081 13.3 0.5 0.88 10.0 0.0 2.5 2 1 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Nudix_N PF12535.8 pCP023447_00004 - 0.1 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF3139 PF11337.8 pCP023447_00004 - 0.91 10.2 8.8 0.14 12.8 1.7 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3139) MFS_1 PF07690.16 pCP023447_00005 - 1.1e-42 146.2 39.9 1.1e-42 146.2 39.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 pCP023447_00005 - 3.9e-10 39.2 8.9 3.9e-10 39.2 8.9 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 pCP023447_00005 - 2.5e-06 26.2 18.2 3e-06 25.9 18.2 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 pCP023447_00005 - 1.2e-05 24.0 43.0 0.00059 18.5 22.9 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein DUF2130 PF09903.9 pCP023447_00006 - 1.7e-46 158.6 15.9 1.7e-46 158.6 15.9 3.8 1 1 3 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2130) zf-ribbon_3 PF13248.6 pCP023447_00006 - 0.19 11.2 0.9 0.3 10.5 0.1 1.6 2 0 0 2 2 2 0 zinc-ribbon domain RNA_pol_N PF01194.17 pCP023447_00006 - 0.53 10.6 2.0 3.7 7.9 0.0 3.4 4 0 0 4 4 4 0 RNA polymerases N / 8 kDa subunit zf-ACC PF17848.1 pCP023447_00006 - 1.6 8.9 5.6 1.7 8.8 0.3 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Cytochrom_C PF00034.21 pCP023447_00007 - 3.7e-14 53.6 0.0 1.8e-10 41.8 0.0 3.1 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 pCP023447_00007 - 5.7e-11 42.6 0.0 2.8e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 pCP023447_00007 - 0.016 15.2 0.0 3.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_C550 PF14495.6 pCP023447_00007 - 0.022 14.5 0.7 0.11 12.3 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 pCP023447_00007 - 0.042 13.6 0.3 7.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 pCP023447_00007 - 0.094 13.2 0.1 20 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c3 DUF3365 PF11845.8 pCP023447_00007 - 0.19 12.1 0.2 3.9 7.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3365) Peptidase_S49_N PF08496.10 pCP023447_00008 - 0.034 14.2 0.3 0.068 13.2 0.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GTP_EFTU PF00009.27 pCP023447_00009 - 2.2e-54 184.0 0.4 3.5e-54 183.3 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 pCP023447_00009 - 2.8e-22 78.6 0.0 7.1e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 pCP023447_00009 - 9.2e-11 42.0 1.5 2.4e-10 40.7 1.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 pCP023447_00009 - 8.2e-07 29.1 0.4 1.6e-06 28.2 0.4 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 pCP023447_00009 - 0.00062 19.1 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 pCP023447_00009 - 0.0046 17.0 0.1 0.05 13.7 0.1 2.2 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 pCP023447_00009 - 0.011 15.3 0.9 0.2 11.2 0.2 3.2 3 1 0 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 pCP023447_00009 - 0.049 13.1 1.0 0.12 11.8 0.1 2.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 pCP023447_00009 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family EFG_II PF14492.6 pCP023447_00009 - 0.085 13.0 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II PTS_EIIA_2 PF00359.22 pCP023447_00010 - 0.00096 19.1 2.8 0.0016 18.4 2.7 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 FANCI_S2 PF14676.6 pCP023447_00010 - 0.028 14.7 0.9 0.04 14.2 0.9 1.3 1 1 0 1 1 1 0 FANCI solenoid 2 Rotamase PF00639.21 pCP023447_00010 - 0.087 13.8 0.1 0.11 13.4 0.1 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Flg_hook PF02120.16 pCP023447_00011 - 2.2e-14 53.1 1.0 1.2e-13 50.7 0.3 2.6 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK FlgD_ig PF13860.6 pCP023447_00012 - 1.8e-18 66.1 0.1 5.2e-18 64.7 0.1 1.8 1 0 0 1 1 1 1 FlgD Ig-like domain FlgD PF03963.14 pCP023447_00012 - 1.1e-16 60.9 11.6 1.1e-16 60.9 11.6 2.3 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region FLgD_tudor PF13861.6 pCP023447_00012 - 1.8e-05 24.9 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 FlgD Tudor-like domain Flg_bbr_C PF06429.13 pCP023447_00013 - 1.2e-19 70.1 4.4 3.4e-19 68.7 1.8 2.9 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 pCP023447_00013 - 7.3e-08 32.2 1.9 2.7e-07 30.4 1.9 2.1 2 0 0 2 2 2 1 Flagella basal body rod protein VWA_N PF08399.11 pCP023447_00013 - 0.046 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 VWA N-terminal DUF3659 PF12396.8 pCP023447_00013 - 0.13 12.1 0.2 41 4.2 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3659) FapA PF03961.13 pCP023447_00014 - 4.3e-54 183.8 24.2 4.3e-54 183.8 24.2 1.3 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ribosomal_L1 PF00687.21 pCP023447_00015 - 0.013 15.2 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family Rep_4 PF05797.11 pCP023447_00015 - 0.021 14.0 0.5 0.037 13.1 0.3 1.3 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Hemerythrin PF01814.23 pCP023447_00016 - 5.9e-08 33.4 3.1 5.9e-08 33.4 3.1 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain CC2D2AN-C2 PF15625.6 pCP023447_00016 - 0.09 12.5 0.1 0.88 9.3 0.0 2.0 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain PulA_N1 PF17999.1 pCP023447_00016 - 0.57 11.0 10.4 0.098 13.4 1.8 2.8 2 1 1 3 3 3 0 Pullulanase N1-terminal domain RPA_interact_C PF14768.6 pCP023447_00016 - 4.5 7.9 9.8 4.4 7.9 0.6 3.2 2 2 1 3 3 3 0 Replication protein A interacting C-terminal Na_sulph_symp PF00939.19 pCP023447_00017 - 3.4e-25 89.0 0.1 3.9e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 pCP023447_00017 - 0.014 14.6 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter Na_sulph_symp PF00939.19 pCP023447_00018 - 4e-09 36.0 1.0 6.8e-09 35.3 1.0 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region ETRAMP PF09716.10 pCP023447_00018 - 0.026 14.6 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Na_sulph_symp PF00939.19 pCP023447_00019 - 1.9e-14 53.6 4.1 1.9e-14 53.6 4.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 pCP023447_00019 - 0.0066 15.7 4.0 0.0085 15.3 4.0 1.3 1 0 0 1 1 1 1 Citrate transporter AGTRAP PF06396.11 pCP023447_00019 - 0.095 12.5 1.3 0.1 12.4 1.3 1.0 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Na_sulph_symp PF00939.19 pCP023447_00020 - 1.9e-14 53.6 11.4 1.9e-14 53.6 11.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region tRNA_Me_trans PF03054.16 pCP023447_00021 - 1.2e-108 363.1 1.7 1.4e-108 362.9 1.7 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ATP_bind_3 PF01171.20 pCP023447_00021 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 PP-loop family ThiI PF02568.14 pCP023447_00021 - 1.4e-06 28.1 0.0 3.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 pCP023447_00021 - 2.5e-06 27.2 0.1 8.4e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 pCP023447_00021 - 3.5e-05 23.0 0.0 0.00049 19.3 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Arginosuc_synth PF00764.19 pCP023447_00021 - 0.00027 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 pCP023447_00021 - 0.031 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Lysine_decarbox PF03641.14 pCP023447_00022 - 2.8e-25 88.9 0.0 2.9e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 pCP023447_00022 - 0.09 12.4 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster4 family LDcluster4 PF18306.1 pCP023447_00023 - 7.8e-06 25.6 0.1 9.3e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 pCP023447_00023 - 0.00045 19.5 0.0 0.00046 19.5 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A SKI PF01202.22 pCP023447_00023 - 0.029 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase Peptidase_C39 PF03412.15 pCP023447_00028 - 2e-16 60.0 0.0 2.6e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pCP023447_00028 - 0.00052 20.0 0.0 0.00072 19.6 0.0 1.1 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 AHJR-like PF18743.1 pCP023447_00028 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 REase_AHJR-like DUF3335 PF11814.8 pCP023447_00028 - 0.1 12.1 0.0 7.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase_C39 like family FliMN_C PF01052.20 pCP023447_00029 - 4.6e-21 74.6 1.5 7.2e-21 74.0 1.5 1.3 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliM PF02154.15 pCP023447_00030 - 4.8e-75 251.7 1.4 6.9e-75 251.2 1.4 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 pCP023447_00030 - 8e-14 51.4 0.3 1.3e-13 50.7 0.3 1.4 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term DUF3567 PF12091.8 pCP023447_00030 - 0.029 14.5 1.3 0.15 12.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) 7TM_GPCR_Sri PF10327.9 pCP023447_00030 - 0.045 12.9 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Pertactin PF03212.14 pCP023447_00030 - 0.085 12.8 0.0 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Pertactin Sld5 PF05916.11 pCP023447_00030 - 0.14 12.6 4.6 0.6 10.6 0.2 2.6 2 1 0 2 2 2 0 GINS complex protein Sigma70_r4 PF04545.16 pCP023447_00031 - 2.9e-18 65.1 2.8 8.2e-18 63.7 2.8 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 pCP023447_00031 - 1.7e-10 40.5 0.0 2.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 pCP023447_00031 - 1.6e-08 34.1 2.3 1.6e-08 34.1 2.3 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 pCP023447_00031 - 0.00075 19.6 5.5 0.0019 18.3 0.2 3.1 3 1 0 3 3 3 1 Sigma-70 region 3 HTH_23 PF13384.6 pCP023447_00031 - 0.0017 18.1 0.1 0.0037 17.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 pCP023447_00031 - 0.0018 18.5 4.1 0.0018 18.5 4.1 2.5 3 1 0 3 3 2 1 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.7 pCP023447_00031 - 0.0027 17.5 0.0 0.0058 16.5 0.0 1.5 1 1 0 1 1 1 1 MarR family HTH_37 PF13744.6 pCP023447_00031 - 0.016 15.1 0.5 0.043 13.8 0.5 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Sds3 PF08598.11 pCP023447_00031 - 0.028 14.4 9.2 0.051 13.6 9.2 1.4 1 0 0 1 1 1 0 Sds3-like HTH_5 PF01022.20 pCP023447_00031 - 0.036 13.9 0.2 0.093 12.6 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR PF01047.22 pCP023447_00031 - 0.04 13.9 2.5 0.042 13.8 0.4 2.1 2 0 0 2 2 2 0 MarR family GerE PF00196.19 pCP023447_00031 - 0.041 13.4 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family IF-2B PF01008.17 pCP023447_00031 - 0.095 11.9 4.0 1.2 8.3 4.0 2.0 1 1 0 1 1 1 0 Initiation factor 2 subunit family TrmB PF01978.19 pCP023447_00031 - 0.11 12.4 1.3 0.26 11.2 0.4 2.1 2 1 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_ECF PF07638.11 pCP023447_00031 - 0.14 12.0 5.8 2 8.3 5.8 2.1 1 1 0 1 1 1 0 ECF sigma factor HTH_WhiA PF02650.14 pCP023447_00031 - 0.15 12.4 8.4 0.046 14.1 4.7 2.1 2 1 0 2 2 2 0 WhiA C-terminal HTH domain DAPDH_C PF16654.5 pCP023447_00031 - 0.15 11.9 1.7 0.33 10.8 0.3 2.0 1 1 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Glyco_hydro_65m PF03632.15 pCP023447_00031 - 0.21 10.4 1.8 0.37 9.6 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 65 central catalytic domain Clr5 PF14420.6 pCP023447_00031 - 2.5 8.4 5.8 1.4 9.2 0.5 2.8 3 0 0 3 3 3 0 Clr5 domain Hema_stalk PF08720.10 pCP023447_00032 - 0.002 17.8 0.1 0.0026 17.5 0.1 1.2 1 0 0 1 1 1 1 Influenza C hemagglutinin stalk DUF5531 PF17671.1 pCP023447_00032 - 0.04 13.8 2.6 0.056 13.3 2.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5531) Neur_chan_memb PF02932.16 pCP023447_00032 - 0.11 12.5 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ParA PF10609.9 pCP023447_00033 - 3.1e-26 92.3 1.4 1.2e-25 90.4 1.4 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 pCP023447_00033 - 2e-19 70.2 0.5 3.7e-19 69.3 0.5 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 pCP023447_00033 - 2.8e-18 66.2 0.0 5.9e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 pCP023447_00033 - 7.6e-12 45.2 1.2 1.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 pCP023447_00033 - 4.9e-07 29.3 0.0 8.8e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 pCP023447_00033 - 6e-07 29.2 0.0 8.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 pCP023447_00033 - 2.7e-06 26.8 3.4 6.4e-06 25.6 0.3 2.3 1 1 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 pCP023447_00033 - 3.6e-05 22.9 0.3 0.0019 17.2 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 pCP023447_00033 - 3.9e-05 23.5 0.2 0.00012 21.9 0.2 1.8 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 pCP023447_00033 - 0.0003 20.1 0.1 0.0007 19.0 0.1 1.6 1 0 0 1 1 1 1 VirC1 protein AAA_24 PF13479.6 pCP023447_00033 - 0.00049 19.9 0.2 0.0011 18.7 0.1 1.7 1 1 1 2 2 2 1 AAA domain AAA_26 PF13500.6 pCP023447_00033 - 0.00067 19.5 0.7 0.5 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 pCP023447_00033 - 0.0024 17.1 0.4 0.13 11.4 0.1 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 pCP023447_00033 - 0.0048 16.8 0.2 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 NTPase SRP54 PF00448.22 pCP023447_00033 - 0.0073 16.0 1.4 0.015 14.9 0.1 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 pCP023447_00033 - 0.06 13.2 0.8 6.1 6.7 0.3 2.7 1 1 1 2 2 2 0 Helicase AAA_18 PF13238.6 pCP023447_00033 - 0.062 13.8 0.4 0.18 12.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 pCP023447_00033 - 0.083 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 pCP023447_00033 - 0.12 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 pCP023447_00034 - 1.1e-42 145.9 0.1 1.8e-42 145.2 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 pCP023447_00034 - 0.00053 20.3 0.0 0.0015 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 pCP023447_00034 - 0.00098 19.2 0.1 0.0037 17.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ResIII PF04851.15 pCP023447_00034 - 0.0015 18.6 0.0 0.0015 18.6 0.0 2.7 1 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 pCP023447_00034 - 0.0015 18.3 0.8 0.0044 16.8 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 pCP023447_00034 - 0.0021 17.7 0.1 0.0079 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 pCP023447_00034 - 0.0022 18.5 0.0 0.0022 18.5 0.0 2.6 2 1 0 2 2 1 1 ABC transporter cobW PF02492.19 pCP023447_00034 - 0.0028 17.3 1.4 0.035 13.7 1.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 pCP023447_00034 - 0.0031 17.5 0.9 0.023 14.6 0.0 2.6 2 2 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 pCP023447_00034 - 0.0031 17.0 0.0 0.0079 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region CbiA PF01656.23 pCP023447_00034 - 0.007 16.4 3.3 0.07 13.2 0.9 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 pCP023447_00034 - 0.0072 16.8 0.9 0.032 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 pCP023447_00034 - 0.011 15.5 0.9 0.13 11.9 0.3 2.7 2 1 0 2 2 1 0 IstB-like ATP binding protein T2SSE PF00437.20 pCP023447_00034 - 0.011 14.8 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 pCP023447_00034 - 0.011 15.7 0.3 0.058 13.4 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 pCP023447_00034 - 0.012 15.5 0.7 0.038 13.9 0.1 2.2 2 1 1 3 3 2 0 RsgA GTPase AAA_16 PF13191.6 pCP023447_00034 - 0.021 15.2 0.0 0.056 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain NB-ARC PF00931.22 pCP023447_00034 - 0.021 14.0 0.0 0.052 12.7 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 pCP023447_00034 - 0.026 15.0 13.2 0.42 11.1 0.3 2.6 2 1 0 2 2 2 0 AAA domain ParA PF10609.9 pCP023447_00034 - 0.038 13.4 0.1 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 pCP023447_00034 - 0.045 13.2 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Roc PF08477.13 pCP023447_00034 - 0.045 14.0 0.6 1 9.6 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 pCP023447_00034 - 0.047 13.7 0.2 0.047 13.7 0.2 2.6 2 1 0 2 2 2 0 AAA domain VirE PF05272.11 pCP023447_00034 - 0.049 13.4 0.1 0.22 11.2 0.0 2.2 3 0 0 3 3 2 0 Virulence-associated protein E NACHT PF05729.12 pCP023447_00034 - 0.056 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 pCP023447_00034 - 0.061 13.8 0.5 0.16 12.4 0.5 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 pCP023447_00034 - 0.062 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 pCP023447_00034 - 0.08 13.3 0.2 0.23 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 pCP023447_00034 - 0.097 13.2 0.1 0.38 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 pCP023447_00034 - 0.12 12.1 1.4 0.28 10.9 0.3 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 pCP023447_00034 - 0.14 11.5 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 pCP023447_00034 - 0.17 12.0 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3391 PF11871.8 pCP023447_00034 - 0.25 11.9 1.7 0.55 10.8 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) NTPase_1 PF03266.15 pCP023447_00034 - 0.52 10.2 3.4 4 7.3 0.5 2.4 1 1 0 2 2 2 0 NTPase HPPK PF01288.20 pCP023447_00035 - 2e-20 73.4 0.0 2.3e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DHquinase_II PF01220.19 pCP023447_00036 - 1e-57 193.7 0.3 1.2e-57 193.4 0.3 1.1 1 0 0 1 1 1 1 Dehydroquinase class II Enoyl_reductase PF12241.8 pCP023447_00036 - 0.016 14.5 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region PCuAC PF04314.13 pCP023447_00036 - 0.035 13.9 0.1 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Copper chaperone PCu(A)C Amidohydro_1 PF01979.20 pCP023447_00037 - 5.3e-61 206.8 0.0 6.2e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 pCP023447_00037 - 1.3e-07 31.5 0.0 0.016 14.7 0.0 3.3 2 2 0 3 3 3 3 Amidohydrolase family Peptidase_S49 PF01343.18 pCP023447_00038 - 6.8e-53 178.8 0.2 8.7e-53 178.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 pCP023447_00038 - 5.5e-06 26.4 0.3 7e-05 22.8 0.3 2.2 1 1 0 1 1 1 1 Clp protease SDH_sah PF01972.16 pCP023447_00038 - 0.00055 19.0 0.3 0.0009 18.3 0.1 1.5 1 1 0 1 1 1 1 Serine dehydrogenase proteinase Ligase_CoA PF00549.19 pCP023447_00038 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 CoA-ligase CsgA PF17334.2 pCP023447_00038 - 0.21 12.3 1.1 3.1 8.6 0.0 2.6 2 1 0 2 2 2 0 Minor curli fiber component A GSH-S_ATP PF02955.16 pCP023447_00039 - 0.056 12.8 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF4821 PF16092.5 pCP023447_00039 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Zn_ribbon_SprT PF17283.2 pCP023447_00040 - 0.0036 17.2 1.1 0.0064 16.4 1.1 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Hemerythrin PF01814.23 pCP023447_00041 - 4.9e-06 27.2 1.4 6.3e-06 26.8 1.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain LANC_like PF05147.13 pCP023447_00041 - 0.022 13.3 0.1 0.028 13.0 0.1 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein RHH_7 PF16777.5 pCP023447_00041 - 0.046 14.1 0.1 0.085 13.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG LUD_dom PF02589.15 pCP023447_00042 - 1.3e-29 103.3 0.2 1.7e-29 102.9 0.2 1.2 1 0 0 1 1 1 1 LUD domain AAA_5 PF07728.14 pCP023447_00042 - 0.068 13.2 0.1 0.19 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsX_ECD PF18075.1 pCP023447_00042 - 0.26 11.9 3.8 2.1 9.0 0.5 2.6 2 1 1 3 3 3 0 FtsX extracellular domain LUD_dom PF02589.15 pCP023447_00043 - 7.8e-52 175.8 0.2 1.3e-51 175.1 0.0 1.4 2 0 0 2 2 2 1 LUD domain DUF3390 PF11870.8 pCP023447_00043 - 9.3e-17 61.2 0.0 1.9e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Fer4_8 PF13183.6 pCP023447_00043 - 1.1e-11 44.9 1.5 3.1e-11 43.6 1.5 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 pCP023447_00043 - 4.6e-09 36.7 2.0 1.1e-08 35.5 2.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 pCP023447_00043 - 1e-08 35.1 8.1 4.4e-08 33.1 7.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 pCP023447_00043 - 1.8e-08 33.9 11.7 0.00027 20.6 2.3 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 pCP023447_00043 - 5.7e-08 33.2 4.6 1.4e-07 32.0 4.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 pCP023447_00043 - 1e-06 28.5 11.3 0.00029 20.8 1.8 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 pCP023447_00043 - 4.8e-06 26.6 5.7 6e-05 23.1 6.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 pCP023447_00043 - 1.8e-05 24.6 11.2 0.018 15.1 1.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 pCP023447_00043 - 4.7e-05 23.4 4.6 0.051 13.7 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_20 PF14691.6 pCP023447_00043 - 0.00016 21.4 2.9 0.06 13.1 0.1 2.5 2 0 0 2 2 2 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_4 PF12800.7 pCP023447_00043 - 0.00031 21.0 11.3 0.00053 20.3 1.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 pCP023447_00043 - 0.0012 19.7 11.6 0.05 14.5 11.9 2.7 1 1 2 3 3 3 3 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 pCP023447_00043 - 0.0022 18.8 5.7 1.1 10.1 1.0 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 pCP023447_00043 - 0.0029 18.4 16.2 0.23 12.5 3.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 pCP023447_00043 - 0.026 14.7 5.7 2 8.6 0.1 2.8 3 0 0 3 3 2 0 4Fe-4S dicluster domain Ribosomal_L5_C PF00673.21 pCP023447_00043 - 0.043 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Fer4_13 PF13370.6 pCP023447_00043 - 0.27 11.8 7.9 0.42 11.2 0.7 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I CCG PF02754.16 pCP023447_00044 - 8.5e-31 106.0 0.4 2.7e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Cysteine-rich domain HTH_11 PF08279.12 pCP023447_00044 - 0.029 14.3 0.1 7.3 6.6 0.0 2.7 2 0 0 2 2 2 0 HTH domain Lactate_perm PF02652.14 pCP023447_00045 - 1.2e-205 684.2 48.6 1.4e-205 683.9 48.6 1.0 1 0 0 1 1 1 1 L-lactate permease CDtoxinA PF03498.14 pCP023447_00046 - 1.1e-49 167.9 0.0 1.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain DUF2141 PF09912.9 pCP023447_00046 - 0.069 13.1 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Exo_endo_phos PF03372.23 pCP023447_00047 - 3.4e-18 66.0 0.2 4.9e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 pCP023447_00047 - 0.17 11.8 0.0 4.2 7.2 0.0 2.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase CDtoxinA PF03498.14 pCP023447_00048 - 1e-45 155.0 0.1 1.4e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 pCP023447_00048 - 1.4e-06 28.9 0.5 3.7e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 pCP023447_00048 - 1.6e-05 25.1 0.4 6.9e-05 23.1 0.4 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF4492 PF14899.6 pCP023447_00049 - 1.7e-25 88.7 8.4 1.7e-25 88.7 8.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4492) Cyt_bd_oxida_I PF01654.17 pCP023447_00050 - 1.6e-171 570.5 23.0 2.1e-171 570.2 23.0 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Oxidored_q5_N PF01059.17 pCP023447_00050 - 1.9 8.6 15.0 9.3 6.4 0.8 4.4 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Cyt_bd_oxida_II PF02322.15 pCP023447_00051 - 4.4e-74 249.6 31.0 5e-74 249.4 31.0 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II TrbL PF04610.14 pCP023447_00051 - 0.002 17.9 11.8 0.002 17.9 11.8 3.9 2 2 2 4 4 4 1 TrbL/VirB6 plasmid conjugal transfer protein DUF334 PF03904.13 pCP023447_00051 - 0.055 13.0 0.9 0.17 11.4 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF5362 PF17319.2 pCP023447_00051 - 0.68 9.8 6.3 1.6 8.6 0.0 3.2 2 1 0 2 2 2 0 Family of unknown function (DUF5362) Asp_Glu_race PF01177.22 pCP023447_00053 - 2e-56 191.4 2.4 2.3e-56 191.2 2.4 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 pCP023447_00053 - 0.00035 20.0 0.4 0.0032 16.9 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase PA PF02225.22 pCP023447_00053 - 0.022 14.7 0.0 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 PA domain AAA_33 PF13671.6 pCP023447_00053 - 0.083 13.1 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain HTH_CodY PF08222.11 pCP023447_00053 - 0.16 11.6 3.3 0.94 9.1 0.2 3.2 4 0 0 4 4 4 0 CodY helix-turn-helix domain UDG PF03167.19 pCP023447_00054 - 1.1e-20 74.2 0.1 1.5e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Lyase_1 PF00206.20 pCP023447_00055 - 8.3e-102 340.8 0.0 1e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 pCP023447_00055 - 4.3e-24 84.7 0.1 1.3e-23 83.1 0.1 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus SH3_17 PF18350.1 pCP023447_00055 - 0.088 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain DcuA_DcuB PF03605.14 pCP023447_00056 - 3.1e-134 447.5 28.5 3.9e-134 447.2 28.5 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter CitMHS PF03600.16 pCP023447_00056 - 0.14 11.3 52.4 0.034 13.4 30.7 2.7 1 1 1 2 2 2 0 Citrate transporter Tmemb_18A PF09771.9 pCP023447_00056 - 7 7.1 5.9 11 6.5 0.0 3.5 2 1 2 4 4 4 0 Transmembrane protein 188 TPR_2 PF07719.17 pCP023447_00057 - 0.0002 21.2 7.6 0.21 11.8 0.3 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat HZS_alpha PF18582.1 pCP023447_00057 - 0.0024 18.3 0.0 0.016 15.7 0.0 2.2 2 0 0 2 2 2 1 Hydrazine synthase alpha subunit middle domain TPR_6 PF13174.6 pCP023447_00057 - 0.33 11.7 2.6 5.5 7.8 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 pCP023447_00057 - 1.5 9.2 4.2 7.7 7.0 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1425 PF07233.12 pCP023447_00058 - 7.2e-08 32.2 0.0 8.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1425) LpoB PF13036.6 pCP023447_00059 - 6.4e-45 152.7 0.1 8e-45 152.4 0.1 1.1 1 0 0 1 1 1 1 Peptidoglycan-synthase activator LpoB DUF3799 PF12684.7 pCP023447_00059 - 0.12 12.1 0.0 0.46 10.2 0.0 1.8 1 1 1 2 2 2 0 PDDEXK-like domain of unknown function (DUF3799) CTP_synth_N PF06418.14 pCP023447_00060 - 0.0094 15.3 1.9 0.4 10.0 0.3 2.3 2 0 0 2 2 2 2 CTP synthase N-terminus Rotamase_2 PF13145.6 pCP023447_00060 - 0.13 13.1 0.4 0.13 13.1 0.4 3.0 3 1 0 3 3 3 0 PPIC-type PPIASE domain CsgG PF03783.14 pCP023447_00061 - 1.9e-06 27.3 3.0 2.2e-06 27.1 1.0 2.0 2 0 0 2 2 2 1 Curli production assembly/transport component CsgG LPP20 PF02169.16 pCP023447_00061 - 0.0011 19.3 6.6 0.0011 19.3 6.6 2.7 2 0 0 2 2 2 1 LPP20 lipoprotein AAA_assoc_2 PF16193.5 pCP023447_00061 - 0.0058 16.9 0.2 0.26 11.6 0.1 2.7 2 0 0 2 2 2 1 AAA C-terminal domain CarbopepD_reg_2 PF13715.6 pCP023447_00061 - 1.4 8.9 6.8 0.78 9.8 0.1 3.6 3 1 1 4 4 4 0 CarboxypepD_reg-like domain Ribosomal_L21p PF00829.21 pCP023447_00062 - 1.1e-31 109.0 5.4 1.2e-31 108.9 5.4 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF5599 PF18141.1 pCP023447_00062 - 0.028 14.6 0.1 0.043 14.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5599) Ribosomal_L27 PF01016.19 pCP023447_00063 - 3.7e-38 129.4 5.0 4.1e-38 129.3 5.0 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein GTP1_OBG PF01018.22 pCP023447_00064 - 1.1e-54 184.2 7.9 1.5e-54 183.8 7.9 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 pCP023447_00064 - 1.3e-21 76.8 0.0 2.1e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 pCP023447_00064 - 2.5e-09 36.9 0.0 5.1e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 pCP023447_00064 - 0.049 12.6 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AA_kinase PF00696.28 pCP023447_00065 - 5.3e-37 127.7 0.6 6.1e-37 127.5 0.6 1.0 1 0 0 1 1 1 1 Amino acid kinase family Formyl_trans_N PF00551.19 pCP023447_00066 - 3e-35 121.6 0.0 4.7e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 pCP023447_00066 - 5.1e-20 71.6 0.0 9.1e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain BPL_LplA_LipB PF03099.19 pCP023447_00067 - 3.8e-13 49.5 0.0 5.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ubiquitin_4 PF18036.1 pCP023447_00067 - 0.034 14.2 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_31 PF13614.6 pCP023447_00068 - 1.3e-65 220.7 3.2 1.3e-65 220.7 3.2 1.5 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 pCP023447_00068 - 3.7e-26 91.7 0.2 5.2e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 pCP023447_00068 - 2.2e-14 53.4 0.9 3.6e-13 49.4 0.5 2.3 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 pCP023447_00068 - 1.6e-12 47.5 0.2 2e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 pCP023447_00068 - 2e-10 40.6 0.0 3.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 pCP023447_00068 - 3.8e-09 36.4 0.5 2.8e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 pCP023447_00068 - 3.8e-08 32.9 0.3 1.2e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 pCP023447_00068 - 6.2e-05 22.4 0.2 0.00018 20.9 0.1 1.7 1 1 0 1 1 1 1 VirC1 protein SRP54 PF00448.22 pCP023447_00068 - 0.0032 17.1 1.2 0.018 14.7 0.2 2.1 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain DUF1027 PF06265.11 pCP023447_00068 - 0.028 14.4 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) DUF1906 PF08924.11 pCP023447_00068 - 0.051 13.7 0.0 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) AAA_24 PF13479.6 pCP023447_00068 - 0.063 13.0 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 pCP023447_00068 - 0.069 12.9 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 pCP023447_00068 - 0.088 12.4 0.1 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 pCP023447_00068 - 0.088 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SecA_DEAD PF07517.14 pCP023447_00068 - 0.25 10.6 1.7 4.8 6.4 0.2 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain ResIII PF04851.15 pCP023447_00068 - 0.54 10.2 3.1 1.2 9.2 0.8 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ParBc PF02195.18 pCP023447_00069 - 5.4e-26 90.7 0.6 3.6e-25 88.1 0.1 2.4 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_ParB PF17762.1 pCP023447_00069 - 1.1e-14 54.0 0.6 1.1e-14 54.0 0.6 2.9 3 0 0 3 3 3 1 HTH domain found in ParB protein Raf1_N PF18578.1 pCP023447_00069 - 0.13 12.8 0.4 23 5.5 0.0 3.0 3 1 0 3 3 3 0 Rubisco accumulation factor 1 alpha helical domain Popeye PF04831.13 pCP023447_00069 - 0.13 12.4 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Popeye protein conserved region HTH_19 PF12844.7 pCP023447_00069 - 0.14 12.2 5.4 14 5.8 0.1 4.3 3 1 0 4 4 4 0 Helix-turn-helix domain LAGLIDADG_WhiA PF14527.6 pCP023447_00069 - 0.25 11.4 4.6 1.3 9.2 0.3 3.0 3 1 0 3 3 3 0 WhiA LAGLIDADG-like domain DUF365 PF04033.12 pCP023447_00069 - 0.81 10.0 3.5 1.2 9.4 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF365) ATP-synt_B PF00430.18 pCP023447_00070 - 2.3e-10 40.7 10.5 3.1e-10 40.3 10.5 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) PMT2_N PF17987.1 pCP023447_00070 - 0.034 14.3 0.7 0.046 13.9 0.7 1.3 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal DUF948 PF06103.11 pCP023447_00070 - 0.041 14.1 1.5 0.095 13.0 0.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PAGK PF15284.6 pCP023447_00070 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor DUF5119 PF17145.4 pCP023447_00070 - 0.067 13.1 0.1 0.08 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) Spc7 PF08317.11 pCP023447_00070 - 0.11 11.4 14.5 0.12 11.2 14.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CSG2 PF16965.5 pCP023447_00070 - 0.17 10.8 1.1 0.19 10.6 1.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator HTH_37 PF13744.6 pCP023447_00070 - 0.19 11.7 6.6 0.27 11.2 2.6 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain Flg_hook PF02120.16 pCP023447_00070 - 0.42 10.5 5.1 5.5 6.9 0.8 2.2 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK ERG2_Sigma1R PF04622.12 pCP023447_00070 - 0.44 9.8 1.7 0.58 9.5 1.2 1.4 1 1 0 1 1 1 0 ERG2 and Sigma1 receptor like protein CemA PF03040.14 pCP023447_00070 - 1.2 9.1 6.4 1.4 8.8 6.4 1.2 1 0 0 1 1 1 0 CemA family Macoilin PF09726.9 pCP023447_00070 - 1.3 7.5 11.1 1.5 7.3 11.1 1.0 1 0 0 1 1 1 0 Macoilin family GrpE PF01025.19 pCP023447_00070 - 6.9 6.3 14.4 1.5 8.4 2.6 2.1 1 1 1 2 2 2 0 GrpE ATP-synt_B PF00430.18 pCP023447_00071 - 0.008 16.3 0.2 0.008 16.3 0.2 1.3 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 pCP023447_00072 - 0.00022 21.6 2.8 0.00022 21.6 2.8 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Plasmid_parti PF01672.16 pCP023447_00072 - 0.0019 18.8 0.8 0.0027 18.3 0.8 1.3 1 0 0 1 1 1 1 Putative plasmid partition protein ATP-synt_B PF00430.18 pCP023447_00072 - 0.0036 17.4 3.6 0.0042 17.2 3.6 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DUF4954 PF16314.5 pCP023447_00072 - 0.011 14.0 1.3 0.011 13.9 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Tweety PF04906.13 pCP023447_00072 - 0.64 8.6 2.7 0.7 8.5 2.7 1.1 1 0 0 1 1 1 0 Tweety OSCP PF00213.18 pCP023447_00073 - 3.3e-22 79.4 3.0 4.5e-22 79.0 3.0 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATP-synt_ab PF00006.25 pCP023447_00074 - 1.4e-76 256.9 0.1 2.1e-76 256.3 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 pCP023447_00074 - 6.3e-51 172.0 0.6 1e-50 171.2 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 pCP023447_00074 - 3e-17 62.9 1.7 9.3e-17 61.3 1.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 pCP023447_00074 - 2.2e-05 23.9 1.4 0.00013 21.4 0.3 2.6 2 0 0 2 2 2 1 KaiC Arginosuc_synth PF00764.19 pCP023447_00074 - 0.046 13.0 0.2 0.082 12.2 0.2 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase HAS-barrel PF09378.10 pCP023447_00074 - 0.061 13.5 0.1 0.25 11.5 0.1 2.1 2 1 0 2 2 2 0 HAS barrel domain Fe_dep_repress PF01325.19 pCP023447_00074 - 0.074 13.3 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain ATP-synt PF00231.19 pCP023447_00075 - 4.2e-83 279.3 12.2 4.7e-83 279.1 12.2 1.0 1 0 0 1 1 1 1 ATP synthase PTEN_C2 PF10409.9 pCP023447_00075 - 0.11 12.3 0.8 0.22 11.3 0.8 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Snf7 PF03357.21 pCP023447_00075 - 0.12 12.0 8.4 0.033 13.8 3.2 2.3 2 0 0 2 2 2 0 Snf7 BLOC1_2 PF10046.9 pCP023447_00075 - 6.4 7.2 11.4 1.6 9.1 1.6 3.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP-synt_ab PF00006.25 pCP023447_00076 - 6.6e-65 218.7 0.0 9.7e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 pCP023447_00076 - 1.2e-18 67.3 0.1 3.4e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 pCP023447_00076 - 0.014 15.2 0.8 0.26 11.2 0.2 2.9 2 1 0 2 2 2 0 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 pCP023447_00076 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 pCP023447_00076 - 0.11 11.7 0.3 0.22 10.7 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 pCP023447_00076 - 0.16 12.3 0.7 0.29 11.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain ATP-synt_DE_N PF02823.16 pCP023447_00077 - 2.7e-24 84.9 0.2 3.3e-24 84.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain MotA_ExbB PF01618.16 pCP023447_00078 - 3.1e-25 88.4 0.1 4e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 pCP023447_00079 - 2.8e-28 98.7 2.3 3.2e-28 98.5 2.3 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_2 PF13103.6 pCP023447_00080 - 1.5e-12 47.6 0.1 2.7e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 TonB C terminal SHE3 PF17078.5 pCP023447_00080 - 0.0069 16.1 2.0 0.011 15.5 2.0 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 TRA-1_regulated PF02343.16 pCP023447_00080 - 0.15 12.1 1.4 0.24 11.5 0.8 1.6 1 1 1 2 2 2 0 TRA-1 regulated protein R03H10.4 DUF3349 PF11829.8 pCP023447_00080 - 0.36 11.6 2.2 0.56 11.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF948 PF06103.11 pCP023447_00080 - 8.7 6.7 6.8 6.2 7.2 3.7 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pectate_lyase22 PF14583.6 pCP023447_00081 - 1.9e-08 33.4 2.3 3.5e-07 29.2 0.3 2.7 1 1 2 3 3 3 1 Oligogalacturonate lyase PD40 PF07676.12 pCP023447_00081 - 2.7e-06 27.1 1.2 0.3 11.1 0.2 3.8 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 pCP023447_00081 - 0.00048 19.0 1.1 0.96 8.1 0.1 2.9 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region TolB_N PF04052.13 pCP023447_00081 - 0.014 15.5 0.1 0.05 13.8 0.1 1.9 2 0 0 2 2 2 0 TolB amino-terminal domain MNE1 PF13762.6 pCP023447_00081 - 0.017 15.1 0.6 0.15 12.0 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component Kelch_3 PF13415.6 pCP023447_00081 - 0.25 11.7 4.5 17 5.9 0.0 3.9 4 1 0 4 4 4 0 Galactose oxidase, central domain NUMOD1 PF07453.13 pCP023447_00081 - 0.72 10.2 4.4 1.5 9.2 0.7 3.3 2 1 1 3 3 3 0 NUMOD1 domain OmpA PF00691.20 pCP023447_00082 - 7.2e-21 74.4 0.0 1.1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 OmpA family ApbE PF02424.15 pCP023447_00082 - 0.028 14.0 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 ApbE family Pilus_CpaD PF09476.10 pCP023447_00082 - 0.051 13.3 0.3 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) TPR_6 PF13174.6 pCP023447_00083 - 5.6e-07 29.8 0.1 0.0029 18.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 pCP023447_00083 - 1.5e-05 24.8 0.1 0.00062 19.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 pCP023447_00083 - 0.00032 20.7 0.5 0.0013 18.8 0.5 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 pCP023447_00083 - 0.00034 20.3 0.7 0.0013 18.4 0.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 pCP023447_00083 - 0.0017 19.0 0.0 0.044 14.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Jnk-SapK_ap_N PF09744.9 pCP023447_00083 - 0.0051 17.0 9.1 0.0051 17.0 9.1 2.2 1 1 2 3 3 3 1 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 pCP023447_00083 - 0.0088 16.3 8.4 0.0088 16.3 8.4 2.7 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CorA PF01544.18 pCP023447_00083 - 0.043 13.1 3.5 0.074 12.4 3.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_19 PF14559.6 pCP023447_00083 - 0.043 14.3 0.1 0.22 12.1 0.0 2.3 3 0 0 3 3 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 pCP023447_00083 - 0.067 13.4 0.4 0.21 11.8 0.3 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 pCP023447_00083 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1664 PF07889.12 pCP023447_00083 - 0.08 13.0 11.4 0.21 11.7 2.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 pCP023447_00083 - 0.85 9.8 23.7 0.13 12.5 14.0 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4407 PF14362.6 pCP023447_00083 - 1.4 8.2 10.9 2.2 7.6 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 pCP023447_00083 - 1.4 8.2 12.8 0.062 12.6 4.3 2.0 2 0 0 2 2 2 0 FAM76 protein DUF4140 PF13600.6 pCP023447_00083 - 1.9 9.0 11.3 12 6.4 0.1 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tweety PF04906.13 pCP023447_00083 - 7.2 5.2 6.4 5 5.7 5.0 1.5 1 1 0 1 1 1 0 Tweety Golgin_A5 PF09787.9 pCP023447_00083 - 8.1 5.8 18.9 35 3.7 18.6 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 FKBP_C PF00254.28 pCP023447_00084 - 2.6e-06 27.7 0.1 5.3e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Acyl_transf_1 PF00698.21 pCP023447_00085 - 6.3e-21 75.2 0.0 7.5e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 pCP023447_00085 - 0.032 14.0 0.0 0.096 12.4 0.0 1.7 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis PNP_UDP_1 PF01048.20 pCP023447_00086 - 4.3e-43 147.2 0.0 5e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily ATP_bind_3 PF01171.20 pCP023447_00087 - 5.8e-22 78.3 0.0 8.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 pCP023447_00087 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 pCP023447_00087 - 0.029 14.0 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase Isochorismatase PF00857.20 pCP023447_00088 - 9.1e-14 52.0 0.0 1e-13 51.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family rpo132 PF12415.8 pCP023447_00088 - 0.14 11.5 0.1 2.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Poxvirus DNA dependent RNA polymerase RecO_N_2 PF13114.6 pCP023447_00089 - 2e-32 110.7 0.1 5.6e-32 109.3 0.0 1.8 2 0 0 2 2 2 1 RecO N terminal Mad3_BUB1_I PF08311.12 pCP023447_00089 - 0.021 14.8 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 RecO_N PF11967.8 pCP023447_00089 - 0.022 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal UPF0054 PF02130.17 pCP023447_00090 - 2.7e-34 117.8 1.0 3.1e-34 117.5 1.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PIG-S PF10510.9 pCP023447_00090 - 0.036 12.9 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF573 PF04504.14 pCP023447_00091 - 0.021 15.5 8.4 0.051 14.2 4.7 2.9 1 1 1 3 3 3 0 Protein of unknown function, DUF573 GNAT_acetyltr_2 PF13718.6 pCP023447_00091 - 0.18 11.2 3.2 0.17 11.2 1.4 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase 2 Dus PF01207.17 pCP023447_00092 - 6.2e-76 255.5 0.0 7.6e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TIM PF00121.18 pCP023447_00092 - 0.00027 20.4 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Triosephosphate isomerase TMP-TENI PF02581.17 pCP023447_00092 - 0.0067 15.8 0.1 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 Thiamine monophosphate synthase PdxJ PF03740.13 pCP023447_00092 - 0.0093 15.1 0.4 0.52 9.4 0.0 2.5 2 1 1 3 3 3 1 Pyridoxal phosphate biosynthesis protein PdxJ BtpA PF03437.15 pCP023447_00092 - 0.056 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 BtpA family EAP30 PF04157.16 pCP023447_00092 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_48 PF17906.1 pCP023447_00092 - 0.18 12.0 0.5 76 3.5 0.0 3.9 4 0 0 4 4 4 0 HTH domain in Mos1 transposase DUF910 PF06014.11 pCP023447_00093 - 0.0037 17.3 2.3 1.9 8.5 0.1 2.8 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF910) Utp13 PF08625.11 pCP023447_00093 - 0.012 15.6 4.3 0.016 15.1 0.4 2.3 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF325 PF03804.13 pCP023447_00093 - 0.076 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Viral proteins of unknown function zf-dskA_traR PF01258.17 pCP023447_00094 - 1.3e-11 44.2 2.3 2.1e-11 43.6 2.3 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Fib_alpha PF08702.10 pCP023447_00094 - 0.1 12.8 3.6 0.77 9.9 0.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1289 PF06945.13 pCP023447_00094 - 0.11 12.3 4.4 0.75 9.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) SPOUT_MTase PF02590.17 pCP023447_00095 - 7.4e-40 136.4 0.5 8.3e-40 136.3 0.5 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase BBP1_C PF15272.6 pCP023447_00095 - 0.001 19.0 1.1 0.0016 18.3 1.1 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Carboxyl_trans PF01039.22 pCP023447_00096 - 1.4e-21 76.8 0.2 3.2e-21 75.5 0.2 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 pCP023447_00096 - 1.1e-07 31.7 9.0 1.9e-07 31.0 9.0 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain RNA_POL_M_15KD PF02150.16 pCP023447_00096 - 0.071 13.0 1.7 0.45 10.4 1.8 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Inositol_P PF00459.25 pCP023447_00097 - 1.3e-14 54.4 0.0 1.9e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 pCP023447_00097 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Bac_surface_Ag PF01103.23 pCP023447_00098 - 4.4e-68 230.2 10.5 7.3e-68 229.4 10.5 1.4 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 pCP023447_00098 - 2e-39 134.0 36.8 8e-13 48.8 3.4 5.7 6 0 0 6 6 6 5 Surface antigen variable number repeat POTRA_2 PF08479.11 pCP023447_00098 - 9e-06 25.4 2.6 0.61 10.0 0.1 5.3 5 0 0 5 5 5 2 POTRA domain, ShlB-type POTRA_1 PF08478.10 pCP023447_00098 - 3.7e-05 23.9 4.5 0.59 10.5 0.1 4.4 4 0 0 4 4 4 2 POTRA domain, FtsQ-type ShlB PF03865.13 pCP023447_00098 - 0.00035 20.1 1.4 0.00057 19.4 0.2 1.9 2 0 0 2 2 2 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB PDH PF02153.17 pCP023447_00099 - 2.6e-69 233.1 0.2 2.9e-69 233.0 0.2 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 pCP023447_00099 - 0.00016 22.2 0.2 0.00063 20.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 pCP023447_00099 - 0.00044 20.5 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IPT PF01745.16 pCP023447_00099 - 0.03 13.7 0.2 0.05 13.0 0.2 1.3 1 0 0 1 1 1 0 Isopentenyl transferase FNIP PF05725.12 pCP023447_00099 - 0.048 13.8 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 FNIP Repeat IlvN PF07991.12 pCP023447_00099 - 0.072 12.7 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF4411 PF14367.6 pCP023447_00099 - 0.13 12.2 0.9 0.21 11.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) Semialdhyde_dh PF01118.24 pCP023447_00099 - 0.15 12.5 0.2 0.46 10.9 0.1 2.0 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M23 PF01551.22 pCP023447_00100 - 1.3e-17 63.7 2.8 1.7e-17 63.4 0.3 2.3 3 0 0 3 3 3 1 Peptidase family M23 Sigma_reg_N PF13800.6 pCP023447_00100 - 0.089 13.1 0.9 0.78 10.1 0.7 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Big_3_2 PF12245.8 pCP023447_00100 - 0.15 12.3 0.7 3.5 7.9 0.1 2.6 2 1 0 2 2 2 0 Bacterial Ig-like domain LpxC PF03331.13 pCP023447_00101 - 2.8e-101 338.6 0.0 3.2e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Peptidase_M22 PF00814.25 pCP023447_00102 - 0.00024 20.9 0.0 0.0003 20.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family GHMP_kinases_N PF00288.26 pCP023447_00103 - 7.8e-10 38.9 0.0 2.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 pCP023447_00103 - 0.00048 20.4 0.0 0.0018 18.6 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal zf-FPG_IleRS PF06827.14 pCP023447_00104 - 0.045 13.6 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS IF-2 PF11987.8 pCP023447_00105 - 3.2e-37 126.8 1.1 3.2e-37 126.8 1.1 2.6 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 pCP023447_00105 - 1.7e-33 115.8 2.5 1.7e-33 115.8 2.5 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 pCP023447_00105 - 6.6e-32 109.1 6.2 3.2e-15 55.7 0.3 3.4 3 0 0 3 3 3 2 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 pCP023447_00105 - 1.6e-11 44.3 0.2 1.6e-11 44.3 0.2 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP023447_00105 - 1.2e-09 38.4 10.1 1.7e-06 28.3 1.4 3.5 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Ras PF00071.22 pCP023447_00105 - 1.5e-06 27.9 0.0 1.5e-06 27.9 0.0 2.5 3 0 0 3 3 3 1 Ras family Arf PF00025.21 pCP023447_00105 - 4.8e-06 26.1 1.7 1.8e-05 24.3 0.0 2.5 3 0 0 3 3 3 1 ADP-ribosylation factor family FeoB_N PF02421.18 pCP023447_00105 - 0.00017 21.2 0.2 0.00096 18.7 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 pCP023447_00105 - 0.00028 20.9 7.5 0.0023 17.8 0.0 3.6 3 1 1 4 4 4 2 RsgA GTPase Roc PF08477.13 pCP023447_00105 - 0.0016 18.6 0.0 0.0044 17.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 pCP023447_00105 - 0.056 13.5 1.6 0.87 9.6 0.0 3.4 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain RBFA PF02033.18 pCP023447_00106 - 1.7e-13 50.9 0.0 1.9e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Ribosome-binding factor A CAAP1 PF15335.6 pCP023447_00106 - 0.027 15.0 0.5 0.13 12.9 0.3 2.2 1 1 1 2 2 2 0 Caspase activity and apoptosis inhibitor 1 PRANC PF09372.10 pCP023447_00106 - 0.079 13.3 0.5 0.89 9.9 0.0 2.2 1 1 0 2 2 2 0 PRANC domain DUF150 PF02576.17 pCP023447_00107 - 3.4e-25 88.2 0.4 1.7e-24 86.0 0.1 1.9 2 0 0 2 2 2 1 RimP N-terminal domain DUF150_C PF17384.2 pCP023447_00107 - 2.4e-18 66.0 2.9 3.5e-18 65.5 2.9 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain LolA_like PF17131.4 pCP023447_00107 - 0.02 14.6 0.6 0.034 13.9 0.6 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein LSM14 PF12701.7 pCP023447_00107 - 0.036 14.2 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain AAA_5 PF07728.14 pCP023447_00108 - 3.8e-12 46.4 0.0 5.9e-10 39.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 pCP023447_00108 - 3e-05 24.4 0.0 0.11 13.0 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 pCP023447_00108 - 0.049 14.0 0.1 0.71 10.2 0.1 2.5 1 1 0 1 1 1 0 AAA domain CHASE5 PF17149.4 pCP023447_00108 - 0.076 12.9 0.7 1.9 8.4 0.1 2.9 2 0 0 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins DUF2330 PF10092.9 pCP023447_00108 - 0.3 10.1 1.7 0.65 9.0 1.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) AAA_11 PF13086.6 pCP023447_00108 - 4.5 7.0 5.3 9.3 5.9 0.1 3.1 2 2 1 3 3 3 0 AAA domain McrBC PF10117.9 pCP023447_00109 - 1.9e-108 362.4 13.0 2.4e-108 362.1 13.0 1.1 1 0 0 1 1 1 1 McrBC 5-methylcytosine restriction system component ABC-3 PF00950.17 pCP023447_00110 - 6.2e-72 242.2 35.7 7e-72 242.0 35.7 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 pCP023447_00110 - 4.2e-10 39.1 35.4 7.4e-10 38.3 35.4 1.4 1 1 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 pCP023447_00111 - 1.3e-28 100.2 0.1 3.5e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 pCP023447_00111 - 3.4e-09 37.0 0.7 0.00028 20.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 pCP023447_00111 - 4.9e-07 29.4 1.0 0.002 17.6 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 pCP023447_00111 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 pCP023447_00111 - 0.00034 20.9 0.1 0.0014 18.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 pCP023447_00111 - 0.00057 19.9 1.5 0.0057 16.6 1.5 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_15 PF13175.6 pCP023447_00111 - 0.0027 17.5 14.7 0.0081 15.9 14.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 pCP023447_00111 - 0.0049 16.5 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 pCP023447_00111 - 0.0056 16.9 0.1 0.13 12.6 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 pCP023447_00111 - 0.011 15.5 0.0 0.099 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP023447_00111 - 0.013 16.0 6.6 0.076 13.5 6.6 2.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 pCP023447_00111 - 0.027 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 pCP023447_00111 - 0.027 14.8 0.0 0.043 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 pCP023447_00111 - 0.033 14.6 0.3 0.13 12.7 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 pCP023447_00111 - 0.043 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 pCP023447_00111 - 0.044 13.8 0.2 0.2 11.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 pCP023447_00111 - 0.062 13.0 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 pCP023447_00111 - 0.084 12.8 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 pCP023447_00111 - 0.12 12.5 0.1 0.3 11.2 0.0 1.8 2 1 1 3 3 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 pCP023447_00111 - 0.15 12.2 0.1 0.54 10.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain ZnuA PF01297.17 pCP023447_00112 - 1.5e-55 188.4 3.1 1.8e-55 188.1 3.1 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic NMT1_3 PF16868.5 pCP023447_00112 - 0.12 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family W2 PF02020.18 pCP023544_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP023544_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pCP023544_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP023544_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pCP023544_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pCP023544_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP023544_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP023544_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP023544_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP023544_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP023544_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP023544_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pCP023544_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP023544_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP023544_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP023544_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP023544_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pCP023544_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP023544_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pCP023544_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP023544_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP023544_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP023544_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP023544_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pCP023544_00008 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pCP023544_00008 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 pCP023544_00009 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP023544_00009 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP023544_00009 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP023544_00009 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP023544_00009 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pCP023544_00010 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pCP023544_00010 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pCP023544_00010 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pCP023544_00011 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP023544_00011 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pCP023544_00011 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 pCP023544_00011 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 pCP023544_00011 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 pCP023544_00011 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 pCP023544_00012 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 pCP023544_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pCP023544_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP023544_00014 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pCP023544_00014 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pCP023544_00014 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP023544_00014 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE TcdA_TcdB PF12919.7 pCP023544_00015 - 0.00084 18.7 3.1 0.00093 18.6 3.1 1.0 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Bcl-2 PF00452.19 pCP023544_00015 - 0.16 12.6 0.3 0.77 10.5 0.1 1.8 1 1 1 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family ESP PF16590.5 pCP023544_00015 - 0.55 10.5 4.8 0.27 11.5 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 pCP023544_00015 - 6.5 6.9 13.7 0.42 10.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function Toprim_3 PF13362.6 pCP023544_00018 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP023544_00018 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP023544_00018 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP023544_00018 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pCP023544_00019 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pCP023544_00019 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 pCP023544_00020 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pCP023544_00020 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pCP023544_00020 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pCP023544_00022 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pCP023544_00023 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pCP023544_00024 - 1.1e-14 54.5 0.0 2.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP023544_00024 - 0.00029 20.3 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP023544_00024 - 0.0018 18.0 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP023544_00024 - 0.0084 15.5 0.0 0.053 12.9 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP023544_00024 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP023544_00024 - 0.15 12.1 1.7 0.77 9.8 1.7 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP023544_00024 - 0.38 10.7 3.0 4.7 7.2 0.0 3.6 3 1 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) VASP_tetra PF08776.11 pCP023544_00024 - 2.7 7.6 6.7 4.7 6.9 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pCP023544_00025 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP023544_00025 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pCP023544_00025 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pCP023544_00026 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pCP023544_00028 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP023544_00028 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pCP023544_00029 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP023544_00029 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pCP023544_00030 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pCP023544_00030 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pCP023544_00030 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 pCP023544_00031 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pCP023544_00032 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pCP023544_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP023544_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP023544_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP023544_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pCP023544_00034 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP023544_00034 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pCP023544_00034 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pCP023544_00034 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 pCP023544_00035 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP023544_00035 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pCP023544_00035 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 pCP023544_00035 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 pCP023544_00036 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 pCP023544_00037 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP023544_00037 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pCP023544_00038 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pCP023544_00039 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP023544_00039 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pCP023544_00040 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP023544_00040 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP023544_00040 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP023544_00040 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP023544_00040 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP023544_00040 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pCP023544_00040 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 pCP023544_00040 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP023544_00040 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP023544_00040 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP023544_00040 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP023544_00040 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pCP023544_00040 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pCP023544_00040 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pCP023544_00040 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pCP023544_00040 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pCP023544_00040 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pCP023544_00040 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pCP023544_00040 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pCP023544_00040 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pCP023544_00040 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pCP023544_00040 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP023544_00040 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP023544_00040 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP023544_00040 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP023544_00040 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP023544_00040 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP023544_00040 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pCP023544_00040 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 pCP023544_00040 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP023544_00040 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP023544_00040 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 pCP023544_00041 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 pCP023544_00042 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP023544_00042 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP023544_00042 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pCP023544_00042 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 pCP023544_00042 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 pCP023544_00043 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP023544_00043 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pCP023544_00044 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pCP023544_00045 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pCP023544_00045 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 pCP023544_00046 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pCP023544_00046 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pCP023544_00046 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pCP023544_00047 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pCP023544_00048 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP023544_00048 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP023544_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP023544_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP023544_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP023544_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP023544_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP023544_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP023544_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP023544_00048 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP023544_00048 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP023544_00048 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP023544_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP023544_00048 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP023544_00048 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP023544_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP023544_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pCP023544_00050 - 2.9e-05 24.0 2.2 2.9e-05 24.0 2.2 1.6 2 0 0 2 2 2 1 PcfJ-like protein Intein_splicing PF14890.6 pCP023544_00050 - 0.0053 16.7 3.0 0.015 15.3 3.0 1.9 1 1 0 1 1 1 1 Intein splicing domain APH PF01636.23 pCP023544_00052 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 pCP023544_00052 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 pCP023544_00052 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 pCP023544_00052 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 pCP023544_00052 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 pCP023544_00053 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP023544_00053 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP023544_00053 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP023544_00053 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP023544_00053 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP023544_00053 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP023544_00053 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP023544_00053 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP023544_00053 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 pCP023544_00055 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 pCP023544_00055 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 pCP023544_00055 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 pCP023544_00055 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 pCP023544_00055 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 pCP023544_00056 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 pCP023544_00057 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pCP023544_00057 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pCP023544_00057 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pCP023544_00057 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 pCP023544_00058 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 pCP023544_00059 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP023544_00059 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pCP023544_00059 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pCP023544_00059 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pCP023544_00059 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pCP023544_00059 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pCP023544_00059 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pCP023544_00059 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pCP023544_00059 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pCP023544_00059 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pCP023544_00059 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pCP023544_00059 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 pCP023544_00059 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 pCP023544_00059 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 pCP023544_00059 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 pCP023544_00059 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 pCP023544_00059 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP023544_00059 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pCP023544_00059 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 pCP023544_00059 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 pCP023544_00059 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 pCP023544_00059 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 pCP023544_00059 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 pCP023544_00059 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 pCP023544_00059 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 pCP023544_00059 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 pCP023544_00059 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 pCP023544_00059 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 pCP023544_00059 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 pCP023544_00059 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 pCP023544_00059 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 pCP023544_00059 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 pCP023544_00059 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pCP023544_00059 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 pCP023544_00059 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 pCP023544_00059 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 pCP023544_00059 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 pCP023544_00060 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP023544_00060 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP023544_00060 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP023544_00060 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP023544_00060 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP023544_00060 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pCP023544_00061 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pCP023544_00062 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pCP023544_00063 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pCP023544_00063 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pCP023544_00063 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pCP023544_00063 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pCP023544_00063 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pCP023544_00063 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pCP023544_00063 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pCP023544_00063 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pCP023544_00064 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP023544_00064 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP023544_00064 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 pCP023544_00065 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 pCP023544_00065 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 pCP023544_00065 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 pCP023544_00066 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 pCP023544_00066 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 pCP023544_00066 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Resolvase PF00239.21 pCP023546_00001 - 3e-12 46.9 0.0 4.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pCP023546_00001 - 0.011 15.5 0.1 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_25 PF13481.6 pCP023546_00002 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pCP023546_00002 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pCP023546_00002 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pCP023546_00002 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pCP023546_00002 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pCP023546_00002 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pCP023546_00002 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 pCP023546_00003 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pCP023546_00004 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pCP023546_00006 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pCP023546_00006 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pCP023546_00006 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 pCP023546_00007 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pCP023546_00007 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 pCP023546_00008 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pCP023546_00008 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pCP023546_00008 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pCP023546_00008 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Sds3 PF08598.11 pCP023546_00011 - 0.041 13.9 5.7 0.048 13.7 5.7 1.2 1 0 0 1 1 1 0 Sds3-like ESP PF16590.5 pCP023546_00011 - 0.48 10.7 5.3 0.26 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 pCP023546_00011 - 4.2 7.5 13.8 0.42 10.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function HTH_46 PF15977.5 pCP023546_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pCP023546_00012 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pCP023546_00012 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pCP023546_00012 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pCP023546_00012 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pCP023546_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF3913 PF13052.6 pCP023546_00014 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Acetyltransf_7 PF13508.7 pCP023546_00015 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pCP023546_00015 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pCP023546_00015 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 pCP023546_00015 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 pCP023546_00015 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 pCP023546_00015 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 NYN PF01936.18 pCP023546_00016 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pCP023546_00016 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pCP023546_00016 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) SNF2_N PF00176.23 pCP023546_00017 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pCP023546_00017 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pCP023546_00017 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pCP023546_00017 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pCP023546_00017 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pCP023546_00018 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pCP023546_00018 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 pCP023546_00019 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pCP023546_00019 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pCP023546_00019 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pCP023546_00019 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pCP023546_00019 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pCP023546_00020 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pCP023546_00020 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pCP023546_00021 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pCP023546_00021 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pCP023546_00021 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pCP023546_00021 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pCP023546_00021 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pCP023546_00022 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pCP023546_00022 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pCP023546_00022 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pCP023546_00022 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pCP023546_00022 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pCP023546_00022 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pCP023546_00022 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pCP023546_00023 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 pCP023546_00024 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pCP023546_00024 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pCP023546_00025 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pCP023546_00025 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Sigma70_r4_2 PF08281.12 pCP023546_00026 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 pCP023546_00026 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 pCP023546_00026 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain zf-HC2 PF13490.6 pCP023546_00027 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 pCP023546_00027 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 pCP023546_00027 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain APH PF01636.23 pCP023546_00028 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pCP023546_00028 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pCP023546_00028 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Acetyltransf_1 PF00583.25 pCP023546_00029 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pCP023546_00029 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pCP023546_00029 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pCP023546_00029 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pCP023546_00029 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pCP023546_00029 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pCP023546_00029 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pCP023546_00029 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Adenyl_transf PF04439.12 pCP023546_00030 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Peptidase_C15 PF01470.17 pCP023546_00031 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pCP023546_00032 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pCP023546_00032 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pCP023546_00032 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pCP023546_00032 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pCP023546_00032 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pCP023546_00032 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_18 PF13238.6 pCP023546_00033 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pCP023546_00033 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pCP023546_00033 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pCP023546_00033 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pCP023546_00033 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pCP023546_00033 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pCP023546_00033 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pCP023546_00033 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pCP023546_00033 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pCP023546_00033 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pCP023546_00033 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pCP023546_00033 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 pCP023546_00033 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 pCP023546_00033 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 pCP023546_00033 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 pCP023546_00033 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 pCP023546_00033 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pCP023546_00033 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pCP023546_00033 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 pCP023546_00033 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 pCP023546_00033 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 pCP023546_00033 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 pCP023546_00033 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 pCP023546_00033 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 pCP023546_00033 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 pCP023546_00033 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 pCP023546_00033 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 pCP023546_00033 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 pCP023546_00033 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 pCP023546_00033 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 pCP023546_00033 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 pCP023546_00033 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 pCP023546_00033 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pCP023546_00033 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 pCP023546_00033 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 pCP023546_00033 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 pCP023546_00033 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family DUF4111 PF13427.6 pCP023546_00034 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) DUF4111 PF13427.6 pCP023546_00035 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pCP023546_00035 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pCP023546_00035 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pCP023546_00035 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain PNP_UDP_1 PF01048.20 pCP023546_00036 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily CPSF_A PF03178.15 pCP023546_00037 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 pCP023546_00037 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 pCP023546_00037 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 pCP023546_00037 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 pCP023546_00037 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) GTP_EFTU PF00009.27 pCP023546_00039 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pCP023546_00039 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pCP023546_00039 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pCP023546_00039 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pCP023546_00039 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pCP023546_00039 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pCP023546_00039 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pCP023546_00039 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pCP023546_00039 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 pCP023546_00040 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 pCP023546_00040 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 pCP023546_00040 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 pCP023546_00040 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 pCP023546_00040 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase PcfJ PF14284.6 pCP023546_00042 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pCP023546_00042 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pCP023546_00043 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pCP023546_00043 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pCP023546_00043 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pCP023546_00043 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pCP023546_00043 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pCP023546_00043 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pCP023546_00043 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pCP023546_00043 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pCP023546_00043 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pCP023546_00043 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pCP023546_00043 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pCP023546_00043 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pCP023546_00043 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pCP023546_00043 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pCP023546_00043 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pCP023546_00043 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pCP023546_00043 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1461 PF07314.11 pCP023546_00044 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CdhD PF03599.16 pCP023546_00045 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pCP023546_00045 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pCP023546_00045 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pCP023546_00046 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pCP023546_00046 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TrbM PF07424.11 pCP023546_00047 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pCP023546_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pCP023546_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) T4SS-DNA_transf PF02534.14 pCP023546_00049 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pCP023546_00049 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pCP023546_00049 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pCP023546_00049 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 pCP023546_00049 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Carbam_trans_N PF02543.15 pCP023546_00050 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T2SSE PF00437.20 pCP023546_00051 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pCP023546_00051 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pCP023546_00051 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pCP023546_00051 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pCP023546_00051 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pCP023546_00051 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pCP023546_00051 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 pCP023546_00051 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pCP023546_00051 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pCP023546_00051 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pCP023546_00051 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pCP023546_00051 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pCP023546_00051 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pCP023546_00051 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pCP023546_00051 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pCP023546_00051 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pCP023546_00051 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pCP023546_00051 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pCP023546_00051 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pCP023546_00051 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pCP023546_00051 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pCP023546_00051 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pCP023546_00051 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pCP023546_00051 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pCP023546_00051 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pCP023546_00051 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pCP023546_00051 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pCP023546_00051 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pCP023546_00051 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 pCP023546_00051 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pCP023546_00051 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pCP023546_00051 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pCP023546_00052 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pCP023546_00052 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pCP023546_00053 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein VirB8 PF04335.13 pCP023546_00054 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pCP023546_00054 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C La_HTH_kDCL PF18177.1 pCP023546_00055 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain TrbL PF04610.14 pCP023546_00056 - 2.8e-30 105.7 32.6 2.8e-30 105.7 32.6 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pCP023546_00056 - 0.072 12.9 0.7 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pCP023546_00056 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 pCP023546_00056 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pCP023546_00057 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pCP023546_00057 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pCP023546_00057 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pCP023546_00057 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 pCP023546_00058 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pCP023546_00058 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pCP023546_00058 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pCP023546_00058 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pCP023546_00059 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 pCP023546_00060 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 pCP023546_00061 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pCP023546_00061 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pCP023546_00061 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 pCP023546_00062 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pCP023546_00062 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 pCP023546_00063 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pCP023546_00063 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pCP023546_00065 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 W2 PF02020.18 pGCA_000015525_00001 - 0.037 14.2 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pGCA_000015525_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_000015525_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pGCA_000015525_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pGCA_000015525_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_000015525_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_000015525_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_000015525_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_000015525_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_000015525_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_000015525_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pGCA_000015525_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_000015525_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_000015525_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_000015525_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_000015525_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_000015525_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_000015525_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_000015525_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_000015525_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_000015525_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_000015525_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_000015525_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pGCA_000015525_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pGCA_000015525_00009 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_000015525_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_000015525_00009 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_000015525_00009 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_000015525_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pGCA_000015525_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_000015525_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pGCA_000015525_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_000015525_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_000015525_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_000015525_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pGCA_000015525_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pGCA_000015525_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pGCA_000015525_00013 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pGCA_000015525_00013 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pGCA_000015525_00013 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pGCA_000015525_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pGCA_000015525_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_000015525_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_000015525_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_000015525_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_000015525_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pGCA_000015525_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pGCA_000015525_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pGCA_000015525_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pGCA_000015525_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pGCA_000015525_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pGCA_000015525_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pGCA_000015525_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pGCA_000015525_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pGCA_000015525_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_000015525_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_000015525_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_000015525_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_000015525_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_000015525_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_000015525_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_000015525_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pGCA_000015525_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_000015525_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_000015525_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_000015525_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pGCA_000015525_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_000015525_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pGCA_000015525_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_000015525_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_000015525_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_000015525_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pGCA_000015525_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pGCA_000015525_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pGCA_000015525_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pGCA_000015525_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pGCA_000015525_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pGCA_000015525_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pGCA_000015525_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pGCA_000015525_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pGCA_000015525_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_000015525_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_000015525_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pGCA_000015525_00033 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_000015525_00033 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_000015525_00033 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pGCA_000015525_00033 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 pGCA_000015525_00033 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 pGCA_000015525_00033 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pGCA_000015525_00033 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pGCA_000015525_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_000015525_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_000015525_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pGCA_000015525_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_000015525_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pGCA_000015525_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_000015525_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_000015525_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_000015525_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pGCA_000015525_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_000015525_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_000015525_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_000015525_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_000015525_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_000015525_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_000015525_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_000015525_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_000015525_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_000015525_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_000015525_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_000015525_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_000015525_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_000015525_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_000015525_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_000015525_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_000015525_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_000015525_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_000015525_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_000015525_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_000015525_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_000015525_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_000015525_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_000015525_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_000015525_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_000015525_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_000015525_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_000015525_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_000015525_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_000015525_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_000015525_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_000015525_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_000015525_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pGCA_000015525_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_000015525_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_000015525_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_000015525_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pGCA_000015525_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_000015525_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_000015525_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_000015525_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pGCA_000015525_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_000015525_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_000015525_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_000015525_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pGCA_000015525_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pGCA_000015525_00046 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_000015525_00046 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_000015525_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_000015525_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_000015525_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_000015525_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_000015525_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_000015525_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_000015525_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_000015525_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_000015525_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_000015525_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_000015525_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_000015525_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_000015525_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_000015525_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_000015525_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pGCA_000015525_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_000015525_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pGCA_000015525_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_000015525_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_000015525_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_000015525_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_000015525_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_000015525_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_000015525_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_000015525_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_000015525_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pGCA_000015525_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pGCA_000015525_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) VirB8 PF04335.13 pGCA_000015525_00052 - 5.3e-29 101.6 0.4 6.2e-29 101.4 0.4 1.0 1 0 0 1 1 1 1 VirB8 protein CagX PF03524.15 pGCA_000015525_00053 - 2.9e-29 102.3 2.4 4.4e-29 101.7 2.4 1.3 1 0 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pGCA_000015525_00054 - 9.8e-42 142.9 1.9 9.8e-42 142.9 1.9 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein VSG_B PF13206.6 pGCA_000015525_00054 - 0.054 12.7 2.4 0.075 12.3 2.4 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain FOXP-CC PF16159.5 pGCA_000015525_00055 - 0.0035 17.9 0.4 0.0041 17.7 0.4 1.2 1 0 0 1 1 1 1 FOXP coiled-coil domain CagS PF16707.5 pGCA_000015525_00055 - 0.12 12.4 7.2 0.13 12.2 7.2 1.0 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori MCR_C PF04609.12 pGCA_000015525_00055 - 0.28 10.2 5.0 0.29 10.2 5.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Aida_N PF08910.10 pGCA_000015525_00055 - 0.5 10.8 5.7 0.52 10.7 5.7 1.0 1 0 0 1 1 1 0 Aida N-terminus Allexi_40kDa PF05549.11 pGCA_000015525_00055 - 1.3 8.5 5.4 1.3 8.5 5.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein T2SSE PF00437.20 pGCA_000015525_00056 - 2.4e-45 154.7 0.0 3e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_000015525_00056 - 4.3e-05 24.0 0.1 6.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_000015525_00056 - 5.1e-05 22.7 0.1 0.0001 21.8 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_000015525_00056 - 5.9e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 pGCA_000015525_00056 - 0.001 18.4 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 pGCA_000015525_00056 - 0.0013 18.7 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Pox_A32 PF04665.12 pGCA_000015525_00056 - 0.0032 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_16 PF13191.6 pGCA_000015525_00056 - 0.0035 17.7 0.0 0.0047 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 pGCA_000015525_00056 - 0.0037 17.3 0.1 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin family ResIII PF04851.15 pGCA_000015525_00056 - 0.0049 16.9 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 pGCA_000015525_00056 - 0.0067 16.7 0.0 0.013 15.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain IIGP PF05049.13 pGCA_000015525_00056 - 0.0084 15.2 0.0 0.04 13.0 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF2075 PF09848.9 pGCA_000015525_00056 - 0.0084 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 pGCA_000015525_00056 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.18 pGCA_000015525_00056 - 0.022 14.1 1.0 0.033 13.5 0.1 1.7 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 pGCA_000015525_00056 - 0.025 14.3 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pGCA_000015525_00056 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DEAD PF00270.29 pGCA_000015525_00056 - 0.033 13.9 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase cobW PF02492.19 pGCA_000015525_00056 - 0.034 13.7 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 pGCA_000015525_00056 - 0.043 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RIX1 PF08167.12 pGCA_000015525_00056 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis NACHT PF05729.12 pGCA_000015525_00056 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 pGCA_000015525_00056 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MobC PF05713.11 pGCA_000015525_00057 - 9.4e-05 22.8 4.8 0.00012 22.4 2.5 2.3 1 1 1 2 2 2 1 Bacterial mobilisation protein (MobC) DUF3810 PF12725.7 pGCA_000015525_00057 - 0.023 14.1 0.2 0.031 13.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) RHH_1 PF01402.21 pGCA_000015525_00057 - 0.079 12.9 0.4 0.24 11.4 0.3 2.0 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family SieB PF14163.6 pGCA_000015525_00057 - 0.15 11.6 6.5 0.72 9.3 0.7 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B T4SS-DNA_transf PF02534.14 pGCA_000015525_00058 - 1.8e-72 244.7 5.8 5.9e-72 243.0 5.4 1.8 1 1 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TrwB_AAD_bind PF10412.9 pGCA_000015525_00058 - 1.8e-25 89.7 0.0 6.8e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 pGCA_000015525_00058 - 1.3e-24 86.6 0.9 6.6e-24 84.3 0.0 2.5 3 0 0 3 3 3 1 TraM recognition site of TraD and TraG DUF418 PF04235.12 pGCA_000015525_00058 - 0.1 12.5 1.4 0.16 11.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF418) DUF1738 PF08401.11 pGCA_000015525_00060 - 8e-10 38.9 0.1 8e-10 38.9 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1738) TrbL PF04610.14 pGCA_000015525_00062 - 1.4e-33 116.4 21.4 1.4e-33 116.4 21.4 2.3 3 0 0 3 3 3 1 TrbL/VirB6 plasmid conjugal transfer protein SHR3_chaperone PF08229.11 pGCA_000015525_00062 - 2.3 7.1 10.1 0.36 9.8 3.1 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 Topoisom_bac PF01131.20 pGCA_000015525_00063 - 5e-89 299.2 9.7 7.3e-89 298.6 9.7 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_000015525_00063 - 9.1e-18 64.4 0.5 9.1e-18 64.4 0.5 3.1 3 1 0 3 3 3 1 Toprim domain Toprim_4 PF13662.6 pGCA_000015525_00063 - 0.066 13.7 0.1 0.31 11.6 0.1 2.3 1 1 0 1 1 1 0 Toprim domain SSB PF00436.25 pGCA_000015525_00065 - 3.5e-24 84.8 0.0 4.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DnaJ-X PF14308.6 pGCA_000015525_00065 - 0.0027 17.2 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 X-domain of DnaJ-containing DUF1981 PF09324.10 pGCA_000015525_00065 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) DUF2512 PF10710.9 pGCA_000015525_00066 - 0.033 13.9 4.4 0.036 13.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) LptF_LptG PF03739.14 pGCA_000015525_00066 - 0.85 8.4 7.6 0.91 8.3 7.6 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF2613 PF11021.8 pGCA_000015525_00066 - 1.1 9.4 3.3 3.1 8.0 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) PND PF17949.1 pGCA_000015525_00067 - 0.096 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 FANCM pseudonuclease domain DUF2583 PF10762.9 pGCA_000015525_00069 - 0.67 10.4 3.8 15 6.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) DUF1189 PF06691.11 pGCA_000015525_00071 - 0.04 13.5 2.2 0.042 13.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Cytomega_TRL10 PF06084.11 pGCA_000015525_00071 - 0.091 12.8 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein HobA PF12163.8 pGCA_000015525_00072 - 0.0094 15.5 0.5 0.012 15.2 0.5 1.1 1 0 0 1 1 1 1 DNA replication regulator Titin_Ig-rpts PF06582.12 pGCA_000015525_00072 - 0.044 13.7 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Titin repeat EptA_B_N PF08019.12 pGCA_000015525_00073 - 0.029 14.3 1.2 0.029 14.3 1.2 2.3 1 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB 7TMR-DISM_7TM PF07695.11 pGCA_000015525_00073 - 0.085 12.7 20.1 0.11 12.3 20.1 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling FeoB_associated PF12669.7 pGCA_000015525_00073 - 1.9 9.0 0.0 1.9 9.0 0.0 2.8 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein Peptidase_M50B PF13398.6 pGCA_000015525_00073 - 2.3 7.8 9.5 0.34 10.5 4.8 1.8 1 1 1 2 2 2 0 Peptidase M50B-like AAA_31 PF13614.6 pGCA_000015525_00077 - 1.3e-21 77.3 3.4 5.9e-15 55.6 0.1 2.5 2 1 1 3 3 3 2 AAA domain CbiA PF01656.23 pGCA_000015525_00077 - 7e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 pGCA_000015525_00077 - 4e-13 49.2 0.1 2.2e-11 43.6 0.1 2.2 1 1 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 pGCA_000015525_00077 - 7e-09 35.3 0.0 8.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 pGCA_000015525_00077 - 5.2e-07 29.4 0.0 5.8e-06 26.0 0.0 2.0 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 pGCA_000015525_00077 - 1.8e-06 27.4 0.1 3e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 pGCA_000015525_00077 - 8.2e-06 25.4 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 pGCA_000015525_00077 - 2.5e-05 24.0 0.0 6.5e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 pGCA_000015525_00077 - 5.5e-05 22.7 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_23 PF13476.6 pGCA_000015525_00077 - 0.00062 20.3 0.8 0.0011 19.6 0.8 1.5 1 1 0 1 1 1 1 AAA domain CTP_transf_3 PF02348.19 pGCA_000015525_00077 - 0.0049 16.8 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase MeaB PF03308.16 pGCA_000015525_00077 - 0.054 12.5 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 pGCA_000015525_00077 - 0.081 13.3 0.1 4.4 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase CLP1_P PF16575.5 pGCA_000015525_00077 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RHH_7 PF16777.5 pGCA_000015525_00078 - 0.074 13.4 9.9 0.57 10.6 2.8 2.6 2 0 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG Rep_3 PF01051.21 pGCA_000015525_00079 - 1.3e-26 93.8 17.6 1.7e-26 93.5 17.6 1.0 1 0 0 1 1 1 1 Initiator Replication protein DUF2362 PF10154.9 pGCA_000015525_00080 - 0.00032 19.8 30.3 0.00032 19.8 30.3 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2362) ORC4_C PF14629.6 pGCA_000015525_00080 - 0.003 17.0 0.9 0.003 17.0 0.9 2.2 2 2 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus HSBP1 PF06825.12 pGCA_000015525_00080 - 0.018 14.9 1.9 0.018 14.9 1.9 4.4 4 0 0 4 4 4 0 Heat shock factor binding protein 1 ApoO PF09769.9 pGCA_000015525_00080 - 0.84 9.6 13.8 8.2 6.4 1.8 4.6 3 2 1 4 4 4 0 Apolipoprotein O WXG100 PF06013.12 pGCA_000015525_00080 - 7 7.0 11.3 1.1 9.6 4.6 3.1 3 2 0 3 3 3 0 Proteins of 100 residues with WXG T4SS PF07996.11 pGCA_000015525_00081 - 2e-07 31.6 7.7 2e-07 31.6 7.7 2.4 1 1 1 2 2 2 1 Type IV secretion system proteins HBM PF16591.5 pGCA_000015525_00081 - 0.0031 17.0 13.0 0.014 14.8 0.2 2.3 2 0 0 2 2 2 1 Helical bimodular sensor domain GUN4_N PF16416.5 pGCA_000015525_00081 - 0.014 15.4 2.2 0.014 15.4 2.2 2.5 2 1 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal Zw10 PF06248.13 pGCA_000015525_00081 - 0.037 12.6 0.3 0.037 12.6 0.3 2.2 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 HTH_16 PF12645.7 pGCA_000015525_00081 - 0.062 13.3 0.5 0.67 10.0 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2730 PF10805.8 pGCA_000015525_00081 - 0.083 13.0 1.5 0.59 10.2 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) NYD-SP28_assoc PF14775.6 pGCA_000015525_00081 - 0.11 12.7 6.8 0.45 10.7 0.8 3.5 2 1 1 3 3 3 0 Sperm tail C-terminal domain SpmSyn_N PF17950.1 pGCA_000015525_00081 - 0.11 12.7 0.9 0.74 10.0 0.1 2.5 2 1 1 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal GCN5L1 PF06320.13 pGCA_000015525_00081 - 0.34 11.0 0.1 0.34 11.0 0.1 3.3 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) Turandot PF07240.11 pGCA_000015525_00081 - 1.2 9.2 4.2 1.3 9.0 0.3 2.7 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot DASH_Dad3 PF08656.10 pGCA_000015525_00081 - 2.8 8.1 8.7 5.6 7.1 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Dad3 Occludin_ELL PF07303.13 pGCA_000015525_00081 - 2.9 8.7 16.9 0.78 10.5 0.5 3.5 1 1 1 3 3 3 0 Occludin homology domain TraF_2 PF13729.6 pGCA_000015525_00081 - 4.3 6.6 13.1 6.3 6.1 0.8 3.0 1 1 2 3 3 3 0 F plasmid transfer operon, TraF, protein FlxA PF14282.6 pGCA_000015525_00081 - 6.3 6.8 24.9 6.7 6.8 5.3 4.1 2 1 2 4 4 4 0 FlxA-like protein TrbM PF07424.11 pGCA_000015525_00082 - 1.4e-34 119.3 2.2 2.2e-34 118.6 2.2 1.3 1 0 0 1 1 1 1 TrbM DUF5442 PF17514.2 pGCA_000015525_00083 - 0.025 14.8 4.8 0.025 14.8 4.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Stn1_C PF12659.7 pGCA_000015525_00083 - 0.028 14.3 2.6 0.066 13.2 2.3 1.8 1 1 1 2 2 2 0 Telomere capping C-terminal wHTH DUF2852 PF11014.8 pGCA_000015525_00083 - 0.035 14.3 0.5 0.035 14.3 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) DUF1856 PF08983.10 pGCA_000015525_00083 - 0.056 13.7 1.2 7.1 6.9 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) Toprim_2 PF13155.6 pGCA_000015525_00084 - 1.8e-12 47.5 0.8 8.8e-12 45.3 0.1 2.3 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 pGCA_000015525_00084 - 7.4e-10 39.1 0.2 2.3e-09 37.4 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3991) Sushi_2 PF09014.10 pGCA_000015525_00084 - 0.064 13.1 0.1 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain YsaB PF13983.6 pGCA_000015525_00086 - 0.1 12.9 0.1 0.34 11.2 0.1 1.8 2 0 0 2 2 2 0 YsaB-like lipoprotein Cytochrom_B_C PF00032.17 pGCA_000015525_00090 - 2.6 8.4 10.0 8.2 6.8 10.0 2.0 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD CpXC PF14353.6 pGCA_000015525_00091 - 0.0096 16.0 2.4 0.012 15.7 2.4 1.3 1 1 0 1 1 1 1 CpXC protein A2L_zn_ribbon PF08792.10 pGCA_000015525_00091 - 0.42 10.4 5.4 2.7 7.8 0.6 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Baculo_p74 PF04583.12 pGCA_000015525_00092 - 0.024 14.1 0.3 0.025 14.1 0.3 1.1 1 0 0 1 1 1 0 Baculoviridae p74 conserved region RasGEF PF00617.19 pGCA_000015525_00092 - 0.044 14.0 0.0 0.044 14.0 0.0 1.1 1 0 0 1 1 1 0 RasGEF domain TetR_C_3 PF08362.11 pGCA_000015525_00095 - 0.019 14.9 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region Arteri_env PF01606.16 pGCA_000015525_00095 - 0.055 13.3 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Arterivirus envelope protein Sipho_tail PF05709.11 pGCA_000015525_00096 - 0.0044 16.5 1.1 0.0056 16.1 1.1 1.1 1 0 0 1 1 1 1 Phage tail protein NRD1_2 PF01995.16 pGCA_000015525_00096 - 0.0063 15.8 1.0 0.008 15.5 0.6 1.5 1 1 1 2 2 2 1 NrpR regulatory domains NRD1 and 2 DUF3755 PF12579.8 pGCA_000015525_00097 - 0.054 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Pox_polyA_pol_N PF12630.7 pGCA_000015525_00097 - 0.53 10.7 0.1 0.53 10.7 0.1 2.1 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain PemK_toxin PF02452.17 pGCA_000015525_00098 - 1.4e-07 31.9 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system DWNN PF08783.11 pGCA_000015525_00098 - 3.1 8.1 7.2 0.34 11.2 2.5 1.8 2 0 0 2 2 2 0 DWNN domain Relaxase PF03432.14 pGCA_000015525_00100 - 3.9e-09 36.5 18.3 3.9e-09 36.5 18.3 3.4 1 1 3 4 4 4 1 Relaxase/Mobilisation nuclease domain MobA_MobL PF03389.15 pGCA_000015525_00100 - 0.015 15.0 8.8 0.058 13.1 8.8 2.1 1 1 0 1 1 1 0 MobA/MobL family Jnk-SapK_ap_N PF09744.9 pGCA_000015525_00100 - 3.6 7.8 20.2 1.5 9.0 9.3 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 VirB3 PF05101.13 pGCA_000015525_00102 - 0.0033 17.6 0.1 0.0038 17.4 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Na_K-ATPase PF00287.18 pGCA_000015525_00102 - 1.1 8.4 3.8 1.2 8.3 3.8 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain TMCO5 PF14992.6 pGCA_000015525_00102 - 5.3 6.5 4.6 5.3 6.5 4.6 1.1 1 0 0 1 1 1 0 TMCO5 family CagE_TrbE_VirB PF03135.14 pGCA_000015525_00103 - 3.8e-28 99.0 7.4 3.8e-28 99.0 7.4 3.6 3 0 0 3 3 3 1 CagE, TrbE, VirB family, component of type IV transporter system TrwB_AAD_bind PF10412.9 pGCA_000015525_00103 - 7.6e-08 31.7 0.3 0.0015 17.5 0.0 2.5 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 pGCA_000015525_00103 - 2e-06 27.0 0.1 1e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.18 pGCA_000015525_00103 - 1.3e-05 24.6 0.0 4.7e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.17 pGCA_000015525_00103 - 0.0049 17.0 14.1 0.034 14.2 0.0 4.1 3 1 0 3 3 3 2 Helicase HerA, central domain AAA_22 PF13401.6 pGCA_000015525_00103 - 0.019 15.3 0.0 0.068 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 pGCA_000015525_00103 - 0.029 14.1 0.3 0.096 12.4 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 pGCA_000015525_00103 - 0.039 14.1 0.3 8 6.6 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 pGCA_000015525_00103 - 0.048 14.2 4.9 0.058 13.9 0.3 3.0 3 1 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 pGCA_000015525_00103 - 0.052 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 pGCA_000015525_00103 - 0.065 13.8 0.0 0.56 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 pGCA_000015525_00103 - 0.1 12.5 0.4 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 NACHT domain W2 PF02020.18 pGCA_000465235_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_000465235_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pGCA_000465235_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_000465235_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain DHHC PF01529.20 pGCA_000465235_00004 - 4.1 7.5 13.1 13 5.9 13.1 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4133 PF13571.6 pGCA_000465235_00004 - 5.6 7.4 7.4 7.5 7.0 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) DHHC PF01529.20 pGCA_000465235_00006 - 0.033 14.3 6.3 0.039 14.0 6.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase T4SS_CagC PF16943.5 pGCA_000465235_00006 - 0.046 13.9 0.2 0.056 13.6 0.2 1.1 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF4044 PF13253.6 pGCA_000465235_00008 - 0.035 13.6 0.8 0.062 12.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_000465235_00008 - 0.065 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2070 PF09843.9 pGCA_000465235_00008 - 0.072 11.4 1.1 0.11 10.8 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_000465235_00008 - 9.1 6.0 13.6 0.15 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_000465235_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_000465235_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) adh_short PF00106.25 pGCA_000465235_00010 - 0.034 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_000465235_00010 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 pGCA_000465235_00011 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pGCA_000465235_00011 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 pGCA_000465235_00012 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_000465235_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_000465235_00012 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_000465235_00012 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_000465235_00012 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pGCA_000465235_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pGCA_000465235_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pGCA_000465235_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pGCA_000465235_00014 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_000465235_00014 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pGCA_000465235_00014 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 pGCA_000465235_00014 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 pGCA_000465235_00014 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 pGCA_000465235_00014 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 pGCA_000465235_00015 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 pGCA_000465235_00016 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_000465235_00017 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_000465235_00017 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pGCA_000465235_00017 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pGCA_000465235_00017 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pGCA_000465235_00017 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pGCA_000465235_00018 - 1.1 9.1 11.3 0.26 11.1 5.3 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pGCA_000465235_00018 - 1.4 9.3 6.9 0.31 11.3 1.2 2.1 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 pGCA_000465235_00018 - 1.7 8.7 15.5 0.15 12.1 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function Ribonuc_2-5A PF06479.12 pGCA_000465235_00022 - 0.065 13.4 5.2 0.2 11.9 5.2 1.9 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF5311 PF17238.2 pGCA_000465235_00022 - 0.065 13.1 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Toprim_3 PF13362.6 pGCA_000465235_00023 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_000465235_00023 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_000465235_00023 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_000465235_00023 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_000465235_00024 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pGCA_000465235_00024 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 pGCA_000465235_00025 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pGCA_000465235_00025 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pGCA_000465235_00025 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pGCA_000465235_00027 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pGCA_000465235_00028 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_000465235_00029 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_000465235_00029 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_000465235_00029 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pGCA_000465235_00029 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pGCA_000465235_00029 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pGCA_000465235_00029 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pGCA_000465235_00029 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pGCA_000465235_00030 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_000465235_00030 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_000465235_00030 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pGCA_000465235_00031 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pGCA_000465235_00033 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_000465235_00033 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_000465235_00034 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_000465235_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pGCA_000465235_00035 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pGCA_000465235_00035 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pGCA_000465235_00035 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 pGCA_000465235_00036 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pGCA_000465235_00037 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_000465235_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_000465235_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_000465235_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_000465235_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pGCA_000465235_00039 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_000465235_00039 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pGCA_000465235_00039 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pGCA_000465235_00039 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 pGCA_000465235_00040 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_000465235_00040 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pGCA_000465235_00040 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 pGCA_000465235_00040 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 pGCA_000465235_00041 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 pGCA_000465235_00042 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_000465235_00042 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_000465235_00043 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pGCA_000465235_00044 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_000465235_00044 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_000465235_00045 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_000465235_00045 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_000465235_00045 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_000465235_00045 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_000465235_00045 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_000465235_00045 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pGCA_000465235_00045 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 pGCA_000465235_00045 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_000465235_00045 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_000465235_00045 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_000465235_00045 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_000465235_00045 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pGCA_000465235_00045 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pGCA_000465235_00045 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pGCA_000465235_00045 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pGCA_000465235_00045 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pGCA_000465235_00045 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pGCA_000465235_00045 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pGCA_000465235_00045 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pGCA_000465235_00045 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pGCA_000465235_00045 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pGCA_000465235_00045 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_000465235_00045 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_000465235_00045 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_000465235_00045 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pGCA_000465235_00045 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pGCA_000465235_00045 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pGCA_000465235_00045 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pGCA_000465235_00045 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 pGCA_000465235_00045 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_000465235_00045 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_000465235_00045 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 pGCA_000465235_00046 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 pGCA_000465235_00047 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_000465235_00047 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_000465235_00047 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pGCA_000465235_00047 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 pGCA_000465235_00047 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 pGCA_000465235_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pGCA_000465235_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pGCA_000465235_00049 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_000465235_00050 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pGCA_000465235_00050 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 pGCA_000465235_00051 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pGCA_000465235_00051 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pGCA_000465235_00051 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pGCA_000465235_00052 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pGCA_000465235_00053 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_000465235_00053 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_000465235_00053 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_000465235_00053 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_000465235_00053 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_000465235_00053 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_000465235_00053 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_000465235_00053 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_000465235_00053 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_000465235_00053 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_000465235_00053 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_000465235_00053 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_000465235_00053 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_000465235_00053 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_000465235_00053 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_000465235_00053 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_000465235_00053 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pGCA_000465235_00054 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_000465235_00054 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain APH PF01636.23 pGCA_000465235_00056 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 pGCA_000465235_00056 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 pGCA_000465235_00056 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 pGCA_000465235_00056 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 pGCA_000465235_00056 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 pGCA_000465235_00057 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_000465235_00057 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_000465235_00057 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_000465235_00057 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_000465235_00057 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_000465235_00057 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_000465235_00057 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_000465235_00057 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_000465235_00057 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 pGCA_000465235_00059 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 pGCA_000465235_00059 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 pGCA_000465235_00059 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 pGCA_000465235_00059 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 pGCA_000465235_00059 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 pGCA_000465235_00060 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 pGCA_000465235_00061 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pGCA_000465235_00061 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pGCA_000465235_00061 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pGCA_000465235_00061 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 pGCA_000465235_00062 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 pGCA_000465235_00063 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pGCA_000465235_00063 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pGCA_000465235_00063 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pGCA_000465235_00063 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pGCA_000465235_00063 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pGCA_000465235_00063 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pGCA_000465235_00063 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pGCA_000465235_00063 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pGCA_000465235_00063 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pGCA_000465235_00063 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pGCA_000465235_00063 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pGCA_000465235_00063 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 pGCA_000465235_00063 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 pGCA_000465235_00063 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 pGCA_000465235_00063 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 pGCA_000465235_00063 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 pGCA_000465235_00063 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_000465235_00063 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pGCA_000465235_00063 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 pGCA_000465235_00063 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 pGCA_000465235_00063 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 pGCA_000465235_00063 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 pGCA_000465235_00063 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 pGCA_000465235_00063 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 pGCA_000465235_00063 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 pGCA_000465235_00063 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 pGCA_000465235_00063 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 pGCA_000465235_00063 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 pGCA_000465235_00063 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 pGCA_000465235_00063 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 pGCA_000465235_00063 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 pGCA_000465235_00063 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 pGCA_000465235_00063 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pGCA_000465235_00063 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 pGCA_000465235_00063 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 pGCA_000465235_00063 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 pGCA_000465235_00063 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 pGCA_000465235_00064 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_000465235_00064 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pGCA_000465235_00064 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pGCA_000465235_00064 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pGCA_000465235_00064 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pGCA_000465235_00064 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pGCA_000465235_00065 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pGCA_000465235_00066 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pGCA_000465235_00067 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pGCA_000465235_00067 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pGCA_000465235_00067 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pGCA_000465235_00067 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pGCA_000465235_00067 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pGCA_000465235_00067 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pGCA_000465235_00067 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pGCA_000465235_00067 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pGCA_000465235_00068 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pGCA_000465235_00068 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pGCA_000465235_00068 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 pGCA_000465235_00069 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 pGCA_000465235_00069 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 pGCA_000465235_00069 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 pGCA_000465235_00070 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 pGCA_000465235_00070 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 pGCA_000465235_00070 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rep_3 PF01051.21 pGCA_000465235_00071 - 1.4e-41 142.7 17.1 1.4e-41 142.7 17.1 1.9 2 1 0 2 2 2 1 Initiator Replication protein Tic110 PF16940.5 pGCA_000465235_00071 - 0.0013 17.4 0.2 0.0021 16.7 0.2 1.3 1 0 0 1 1 1 1 Chloroplast envelope transporter Rad1 PF02144.16 pGCA_000465235_00071 - 0.0033 16.5 0.4 0.0051 15.9 0.4 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Cas_Cas6 PF01881.16 pGCA_000465235_00071 - 0.16 12.5 0.2 0.16 12.5 0.2 3.0 1 1 2 3 3 3 0 CRISPR associated protein Cas6 Peptidase_M15_2 PF05951.13 pGCA_000465235_00071 - 1.2 8.8 5.0 20 4.8 0.4 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF882) VbhA PF18495.1 pGCA_000465235_00072 - 0.092 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Antitoxin VbhA KNOX2 PF03791.13 pGCA_000465235_00072 - 0.11 12.1 0.2 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 KNOX2 domain BT1 PF03092.16 pGCA_000465235_00074 - 0.0025 16.1 0.2 0.0027 16.0 0.2 1.0 1 0 0 1 1 1 1 BT1 family MARVEL PF01284.23 pGCA_000465235_00074 - 0.0028 17.7 0.6 0.003 17.6 0.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain ATP-synt_I PF03899.15 pGCA_000465235_00074 - 0.0038 17.6 3.5 0.0041 17.5 3.5 1.1 1 0 0 1 1 1 1 ATP synthase I chain DUF1772 PF08592.11 pGCA_000465235_00074 - 0.017 15.5 0.1 0.017 15.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) TctB PF07331.11 pGCA_000465235_00074 - 0.18 12.1 5.4 0.22 11.8 5.4 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family YvrJ PF12841.7 pGCA_000465235_00074 - 0.23 11.0 0.1 0.23 11.0 0.1 2.3 3 0 0 3 3 3 0 YvrJ protein family DUF4131 PF13567.6 pGCA_000465235_00074 - 0.91 9.2 3.4 1.1 8.9 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) W2 PF02020.18 pGCA_000583775_00001 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pGCA_000583775_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_000583775_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 pGCA_000583775_00003 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_000583775_00003 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_000583775_00003 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pGCA_000583775_00003 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pGCA_000583775_00003 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pGCA_000583775_00003 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pGCA_000583775_00003 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_000583775_00003 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pGCA_000583775_00003 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pGCA_000583775_00004 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_000583775_00004 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_000583775_00004 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_000583775_00004 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_000583775_00004 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_000583775_00005 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_000583775_00005 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_000583775_00006 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_000583775_00006 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_000583775_00006 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_000583775_00006 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_000583775_00006 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase SNF2_N PF00176.23 pGCA_000583775_00008 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_000583775_00008 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_000583775_00008 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_000583775_00008 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_000583775_00008 - 2.9e-05 24.5 0.6 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pGCA_000583775_00009 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_000583775_00009 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pGCA_000583775_00010 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_000583775_00011 - 5.2e-05 23.2 6.1 0.063 13.3 1.0 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_000583775_00011 - 0.036 14.2 2.3 0.046 13.8 1.6 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_000583775_00011 - 0.21 11.7 7.8 0.93 9.6 0.3 2.9 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Imm41 PF15592.6 pGCA_000583775_00012 - 0.031 14.6 2.2 0.034 14.5 2.2 1.0 1 0 0 1 1 1 0 Immunity protein 41 DUF2400 PF09674.10 pGCA_000583775_00014 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pGCA_000583775_00015 - 1.9e-08 34.5 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_000583775_00015 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_000583775_00015 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_000583775_00015 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_000583775_00016 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pGCA_000583775_00017 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pGCA_000583775_00017 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pGCA_000583775_00017 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pGCA_000583775_00019 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pGCA_000583775_00020 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_000583775_00021 - 1.6e-14 54.0 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_000583775_00021 - 0.00038 19.9 0.0 0.0019 17.6 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_000583775_00021 - 0.0022 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_000583775_00021 - 0.009 16.4 0.2 0.22 11.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_000583775_00021 - 0.0091 15.4 0.0 0.058 12.7 0.0 2.3 2 1 0 2 2 2 1 KaiC CbiA PF01656.23 pGCA_000583775_00021 - 0.16 12.0 1.6 0.74 9.9 1.6 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pGCA_000583775_00021 - 0.37 10.8 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pGCA_000583775_00022 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_000583775_00022 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_000583775_00022 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_000583775_00022 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pGCA_000583775_00023 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_000583775_00023 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pGCA_000583775_00025 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_000583775_00025 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_000583775_00026 - 3.3e-50 171.1 0.4 7.5e-50 169.9 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_000583775_00026 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pGCA_000583775_00026 - 0.046 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pGCA_000583775_00027 - 3e-29 101.4 0.0 4.8e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pGCA_000583775_00027 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 pGCA_000583775_00027 - 0.071 13.1 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) DUF3251 PF11622.8 pGCA_000583775_00028 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pGCA_000583775_00028 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pGCA_000583775_00028 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pGCA_000583775_00028 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pGCA_000583775_00028 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pGCA_000583775_00028 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pGCA_000583775_00029 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_000583775_00030 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_000583775_00030 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_000583775_00030 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_000583775_00030 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pGCA_000583775_00031 - 5.3e-28 98.8 13.9 6.9e-28 98.4 13.9 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_000583775_00031 - 0.0037 17.4 0.4 0.016 15.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_000583775_00031 - 0.0077 16.9 5.4 0.0077 16.9 5.4 2.4 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pGCA_000583775_00031 - 0.064 12.8 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pGCA_000583775_00031 - 0.11 13.2 3.6 0.08 13.6 1.1 2.1 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pGCA_000583775_00031 - 3.8 7.8 11.9 1.6 9.0 0.2 2.9 2 1 1 3 3 3 0 Tho complex subunit 7 DHR10 PF18595.1 pGCA_000583775_00031 - 5.9 7.0 14.5 0.64 10.1 6.3 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pGCA_000583775_00032 - 2.9e-31 108.9 34.2 2.9e-31 108.9 34.2 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_000583775_00032 - 0.059 13.2 2.2 0.093 12.5 0.2 2.4 2 1 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_000583775_00032 - 0.29 12.1 6.0 0.57 11.1 6.0 1.5 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 VirB8 PF04335.13 pGCA_000583775_00034 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_000583775_00034 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_000583775_00035 - 2e-54 184.5 1.3 3.3e-54 183.8 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_000583775_00035 - 0.053 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pGCA_000583775_00036 - 5.5e-48 163.3 0.1 5.5e-48 163.3 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_000583775_00036 - 0.027 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_000583775_00037 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_000583775_00037 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_000583775_00037 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_000583775_00037 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_000583775_00037 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_000583775_00037 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_000583775_00037 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_000583775_00037 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_000583775_00037 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_000583775_00037 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_000583775_00037 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_000583775_00037 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_000583775_00037 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_000583775_00037 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_000583775_00037 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_000583775_00037 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_000583775_00037 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_000583775_00037 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_000583775_00037 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_000583775_00037 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_000583775_00037 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_000583775_00037 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_000583775_00037 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_000583775_00037 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_000583775_00037 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_000583775_00037 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_000583775_00037 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_000583775_00037 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_000583775_00037 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_000583775_00037 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_000583775_00037 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pGCA_000583775_00038 - 7.4e-106 354.7 0.1 1e-105 354.3 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_000583775_00038 - 9.5e-25 87.0 0.0 1.9e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_000583775_00038 - 3.7e-15 55.7 0.0 1.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 pGCA_000583775_00039 - 1.5e-16 60.7 0.2 2e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pGCA_000583775_00039 - 0.061 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pGCA_000583775_00040 - 2.1e-38 131.7 1.2 2.8e-38 131.3 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_000583775_00041 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_000583775_00041 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_000583775_00041 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pGCA_000583775_00043 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pGCA_000583775_00044 - 1.4e-96 324.0 8.0 2e-96 323.6 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_000583775_00044 - 1e-11 44.9 0.0 1e-11 44.9 0.0 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_000583775_00044 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_000583775_00044 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_000583775_00044 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_000583775_00044 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_000583775_00044 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 pGCA_000583775_00044 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 pGCA_000583775_00044 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_000583775_00044 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pGCA_000583775_00044 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_000583775_00044 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_000583775_00044 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_000583775_00044 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_000583775_00044 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_000583775_00044 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_000583775_00044 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type NmrA PF05368.13 pGCA_000583775_00046 - 0.017 14.7 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family GTP_EFTU PF00009.27 pGCA_000583775_00048 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_000583775_00048 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_000583775_00048 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_000583775_00048 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_000583775_00048 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_000583775_00048 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_000583775_00048 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_000583775_00048 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_000583775_00048 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 pGCA_000583775_00049 - 1.5e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pGCA_000583775_00049 - 3.5e-06 27.0 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pGCA_000583775_00049 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pGCA_000583775_00049 - 0.088 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication APH PF01636.23 pGCA_000583775_00050 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_000583775_00050 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pGCA_000583775_00050 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pGCA_000583775_00050 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pGCA_000583775_00050 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pGCA_000583775_00050 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pGCA_000583775_00051 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pGCA_000583775_00052 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pGCA_000583775_00053 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pGCA_000583775_00053 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pGCA_000583775_00053 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pGCA_000583775_00053 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pGCA_000583775_00053 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pGCA_000583775_00053 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pGCA_000583775_00053 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pGCA_000583775_00053 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pGCA_000583775_00054 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pGCA_000583775_00054 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pGCA_000583775_00054 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 pGCA_000583795_00001 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pGCA_000583795_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_000583795_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pGCA_000583795_00003 - 0.0072 15.7 2.9 0.0072 15.7 2.9 1.6 2 0 0 2 2 2 1 Putative Flagellin, Flp1-like, domain Y1_Tnp PF01797.16 pGCA_000583795_00004 - 4e-36 123.8 1.9 4.7e-36 123.6 1.9 1.1 1 0 0 1 1 1 1 Transposase IS200 like Symplekin_C PF12295.8 pGCA_000583795_00004 - 0.042 14.0 0.2 0.049 13.7 0.2 1.1 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal DUF4974 PF16344.5 pGCA_000583795_00004 - 0.47 10.5 3.6 0.16 12.0 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) OrfB_Zn_ribbon PF07282.11 pGCA_000583795_00005 - 3.2e-21 75.0 0.5 6.9e-21 73.9 0.5 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 pGCA_000583795_00005 - 2.4e-20 71.7 1.5 4.8e-20 70.8 1.5 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 pGCA_000583795_00005 - 7.6e-20 71.3 2.2 1.9e-19 70.0 2.2 1.6 1 0 0 1 1 1 1 Probable transposase HypA PF01155.19 pGCA_000583795_00005 - 0.19 11.7 0.7 0.42 10.6 0.7 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 pGCA_000583795_00005 - 0.32 11.1 1.5 1.3 9.2 1.5 2.1 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 pGCA_000583795_00005 - 2.3 7.7 5.7 16 5.0 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 pGCA_000583795_00005 - 3.9 7.5 5.0 3.2 7.8 2.0 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ima1_N PF09779.9 pGCA_000583795_00005 - 5 8.0 7.5 1.7 9.5 0.7 2.9 2 1 1 3 3 3 0 Ima1 N-terminal domain LysE PF01810.18 pGCA_000583795_00006 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_000583795_00006 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_000583795_00006 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pGCA_000583795_00006 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pGCA_000583795_00006 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pGCA_000583795_00006 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pGCA_000583795_00006 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_000583795_00006 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pGCA_000583795_00006 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pGCA_000583795_00007 - 0.0042 16.6 1.2 0.0059 16.1 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4044) NPA PF16469.5 pGCA_000583795_00008 - 0.057 14.0 6.1 0.06 13.9 6.1 1.0 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Papo_T_antigen PF02380.15 pGCA_000583795_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_000583795_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_000583795_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_000583795_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_000583795_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_000583795_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_000583795_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pGCA_000583795_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pGCA_000583795_00012 - 1.7e-16 59.9 1.2 4e-16 58.7 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_000583795_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_000583795_00012 - 9.6e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_000583795_00012 - 6.3e-06 26.1 1.8 0.0012 18.7 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_000583795_00012 - 1.5e-05 25.5 0.7 0.00015 22.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pGCA_000583795_00013 - 1.1e-09 38.9 1.0 4.7e-09 36.9 1.0 2.0 1 1 0 1 1 1 1 NYN domain HTH_19 PF12844.7 pGCA_000583795_00014 - 7.3e-06 25.9 0.1 0.012 15.6 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pGCA_000583795_00014 - 7.9e-06 25.8 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pGCA_000583795_00014 - 0.00077 19.5 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pGCA_000583795_00014 - 0.0073 15.8 0.0 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pGCA_000583795_00014 - 0.0088 16.1 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pGCA_000583795_00014 - 0.01 15.7 0.2 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pGCA_000583795_00014 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 pGCA_000583795_00014 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 pGCA_000583795_00014 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 pGCA_000583795_00014 - 0.073 12.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Relaxase PF03432.14 pGCA_000583795_00015 - 4.1e-10 39.7 7.6 4.1e-10 39.7 7.6 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_000583795_00016 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_000583795_00016 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_000583795_00016 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pGCA_000583795_00016 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pGCA_000583795_00016 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Sds3 PF08598.11 pGCA_000583795_00017 - 0.027 14.5 5.8 0.032 14.3 5.8 1.1 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pGCA_000583795_00017 - 0.21 11.4 8.2 0.23 11.3 5.3 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3671 PF12420.8 pGCA_000583795_00017 - 4.6 7.3 14.1 0.42 10.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function CdiI PF07262.11 pGCA_000583795_00017 - 8.8 6.1 12.2 16 5.3 12.2 1.5 1 1 0 1 1 1 0 CDI immunity protein DUF2400 PF09674.10 pGCA_000583795_00019 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pGCA_000583795_00020 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_000583795_00020 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_000583795_00020 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_000583795_00020 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_000583795_00021 - 0.0028 17.6 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pGCA_000583795_00022 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pGCA_000583795_00022 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pGCA_000583795_00022 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pGCA_000583795_00024 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pGCA_000583795_00025 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_000583795_00026 - 5.4e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_000583795_00026 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_000583795_00026 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pGCA_000583795_00026 - 0.0088 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pGCA_000583795_00026 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pGCA_000583795_00026 - 0.21 11.7 2.2 1.1 9.4 2.2 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pGCA_000583795_00026 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pGCA_000583795_00027 - 1.3e-33 116.2 0.8 2.2e-33 115.4 0.8 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain CRISPR_Cas2 PF09827.9 pGCA_000583795_00027 - 0.0016 18.5 0.0 0.016 15.3 0.0 2.6 1 1 0 1 1 1 1 CRISPR associated protein Cas2 PAS_11 PF14598.6 pGCA_000583795_00027 - 0.0032 17.6 1.2 0.023 14.8 0.4 2.3 2 0 0 2 2 2 1 PAS domain Occludin_ELL PF07303.13 pGCA_000583795_00027 - 0.12 13.1 9.1 0.043 14.5 6.0 1.8 2 0 0 2 2 2 0 Occludin homology domain HTH_38 PF13936.6 pGCA_000583795_00027 - 0.2 11.5 1.5 22 4.9 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Pox_A_type_inc PF04508.12 pGCA_000583795_00027 - 6.5 6.8 6.9 0.97 9.4 2.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TrbC PF04956.13 pGCA_000583795_00029 - 1.5e-14 54.0 8.5 1.6e-14 53.9 8.5 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_000583795_00029 - 0.056 13.3 4.3 0.073 12.9 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) VirB3 PF05101.13 pGCA_000583795_00030 - 2e-13 50.4 1.9 2.1e-13 50.3 1.9 1.0 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein CagE_TrbE_VirB PF03135.14 pGCA_000583795_00031 - 3.7e-51 174.2 0.6 8.4e-51 173.0 0.6 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system HNOBA PF07701.14 pGCA_000583795_00031 - 0.039 13.4 0.1 0.085 12.3 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pGCA_000583795_00032 - 3.1e-31 107.8 0.1 5e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) FapA PF03961.13 pGCA_000583795_00033 - 0.0039 15.9 6.9 0.0039 15.9 6.9 1.6 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 pGCA_000583795_00033 - 0.028 14.3 4.0 0.028 14.3 4.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Fib_alpha PF08702.10 pGCA_000583795_00033 - 0.6 10.3 12.2 0.061 13.5 4.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 pGCA_000583795_00033 - 1.7 8.4 11.6 0.92 9.3 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator Striatin PF08232.12 pGCA_000583795_00033 - 4.6 7.8 9.6 14 6.2 9.6 1.9 1 1 0 1 1 1 0 Striatin family Syntaxin-6_N PF09177.11 pGCA_000583795_00033 - 9.3 6.9 10.2 1.8 9.2 4.5 2.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal SSB PF00436.25 pGCA_000583795_00035 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_000583795_00036 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_000583795_00036 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_000583795_00036 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_000583795_00036 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pGCA_000583795_00037 - 3.9e-12 47.0 0.4 4.8e-12 46.7 0.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins GldM_N PF12081.8 pGCA_000583795_00037 - 0.033 14.3 0.5 0.054 13.6 0.5 1.4 1 0 0 1 1 1 0 GldM N-terminal domain T4SS PF07996.11 pGCA_000583795_00038 - 3.3e-10 40.7 11.1 3.8e-10 40.5 11.1 1.0 1 0 0 1 1 1 1 Type IV secretion system proteins AATF-Che1 PF13339.6 pGCA_000583795_00038 - 0.0044 17.7 2.4 0.0052 17.5 2.4 1.1 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor DHR10 PF18595.1 pGCA_000583795_00038 - 0.023 14.7 5.2 0.031 14.3 5.2 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 pGCA_000583795_00038 - 0.032 14.9 0.6 0.032 14.9 0.6 2.0 1 1 0 2 2 2 0 Occludin homology domain VWA_2 PF13519.6 pGCA_000583795_00038 - 0.067 13.8 1.1 0.1 13.3 0.8 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain Snapin_Pallidin PF14712.6 pGCA_000583795_00038 - 0.1 13.0 5.1 0.28 11.6 5.1 1.8 1 1 0 1 1 1 0 Snapin/Pallidin TrbL PF04610.14 pGCA_000583795_00039 - 8.7e-32 110.6 33.1 8.7e-32 110.6 33.1 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_000583795_00039 - 0.029 14.2 1.4 0.055 13.3 0.1 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 pGCA_000583795_00040 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pGCA_000583795_00040 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pGCA_000583795_00040 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pGCA_000583795_00041 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_000583795_00041 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_000583795_00042 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pGCA_000583795_00042 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 pGCA_000583795_00042 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pGCA_000583795_00043 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_000583795_00043 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_000583795_00044 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_000583795_00044 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_000583795_00044 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_000583795_00044 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_000583795_00044 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_000583795_00044 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pGCA_000583795_00044 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pGCA_000583795_00044 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_000583795_00044 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_000583795_00044 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_000583795_00044 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_000583795_00044 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pGCA_000583795_00044 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pGCA_000583795_00044 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pGCA_000583795_00044 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pGCA_000583795_00044 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pGCA_000583795_00044 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pGCA_000583795_00044 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pGCA_000583795_00044 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pGCA_000583795_00044 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_000583795_00044 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 pGCA_000583795_00044 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 pGCA_000583795_00044 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_000583795_00044 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_000583795_00044 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pGCA_000583795_00044 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pGCA_000583795_00044 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pGCA_000583795_00044 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pGCA_000583795_00044 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 pGCA_000583795_00044 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_000583795_00044 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_000583795_00044 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pGCA_000583795_00045 - 1e-105 354.3 0.1 1.4e-105 353.8 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_000583795_00045 - 1.1e-24 86.8 0.0 2.2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_000583795_00045 - 6.5e-16 58.2 0.0 1.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pGCA_000583795_00045 - 0.2 11.7 0.2 0.34 10.9 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 pGCA_000583795_00046 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pGCA_000583795_00046 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pGCA_000583795_00047 - 1.1e-36 126.1 1.8 1.3e-36 125.8 1.8 1.0 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_000583795_00048 - 0.03 14.1 2.2 0.033 14.0 0.3 2.0 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pGCA_000583795_00048 - 2.4 7.9 10.1 5 6.9 8.4 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NdhM PF10664.9 pGCA_000583795_00048 - 2.5 8.4 6.1 57 4.0 0.3 3.2 2 1 1 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M IFT20 PF14931.6 pGCA_000583795_00048 - 4.8 7.4 10.0 1.3 9.2 0.8 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Mod_r PF07200.13 pGCA_000583795_00048 - 8.2 6.5 12.0 85 3.2 9.1 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CdhD PF03599.16 pGCA_000583795_00049 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pGCA_000583795_00049 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pGCA_000583795_00049 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pGCA_000583795_00050 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pGCA_000583795_00051 - 9e-97 324.7 8.0 1.3e-96 324.2 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_000583795_00051 - 9.7e-12 45.0 0.1 9.7e-12 45.0 0.1 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_000583795_00051 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_000583795_00051 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_000583795_00051 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_000583795_00051 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_000583795_00051 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 pGCA_000583795_00051 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 pGCA_000583795_00051 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_000583795_00051 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pGCA_000583795_00051 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_000583795_00051 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_000583795_00051 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_000583795_00051 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_000583795_00051 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_000583795_00051 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_000583795_00051 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pGCA_000583795_00053 - 3.9e-05 23.6 2.2 0.0001 22.2 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_000583795_00053 - 0.02 14.9 4.4 0.16 11.9 4.4 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pGCA_000583795_00055 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_000583795_00055 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_000583795_00055 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_000583795_00055 - 3e-12 46.4 0.1 6.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_000583795_00055 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_000583795_00055 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_000583795_00055 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_000583795_00055 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_000583795_00055 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family TraC_F_IV PF11130.8 pGCA_000736415_00001 - 7.6e-30 104.3 0.0 1.4e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 pGCA_000736415_00001 - 3.3e-10 39.4 0.0 1.7e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 pGCA_000736415_00001 - 0.00074 18.5 0.0 0.8 8.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 pGCA_000736415_00001 - 0.0072 16.6 0.1 4.1 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zot PF05707.12 pGCA_000736415_00001 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) FH2 PF02181.23 pGCA_000736415_00001 - 0.016 14.4 1.1 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain CbiA PF01656.23 pGCA_000736415_00001 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UPF0181 PF03701.14 pGCA_000736415_00001 - 0.22 11.2 0.5 0.67 9.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) TrbI_Ftype PF09677.10 pGCA_000736415_00002 - 2.1e-05 24.8 1.3 2.5e-05 24.6 1.3 1.4 1 1 0 1 1 1 1 Type-F conjugative transfer system protein (TrbI_Ftype) Peptidase_S26 PF10502.9 pGCA_000736415_00003 - 2.2e-13 50.2 0.0 3.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 TraH PF06122.11 pGCA_000736415_00004 - 5.6e-68 229.8 2.0 7.8e-68 229.4 2.0 1.2 1 0 0 1 1 1 1 Conjugative relaxosome accessory transposon protein TraN PF06986.11 pGCA_000736415_00006 - 4.3e-29 101.9 9.8 4.3e-29 101.9 9.8 4.9 2 2 3 5 5 5 2 Type-1V conjugative transfer system mating pair stabilisation Staphylokinase PF02821.16 pGCA_000736415_00011 - 0.075 13.5 5.2 2.6 8.5 1.5 2.1 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family HTH_19 PF12844.7 pGCA_000736415_00013 - 9.4e-08 32.0 0.6 3.6e-07 30.1 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 pGCA_000736415_00013 - 3.1e-06 27.1 0.2 5.9e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pGCA_000736415_00013 - 0.0061 17.0 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Phage_CI_repr PF07022.13 pGCA_000736415_00013 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_25 PF13413.6 pGCA_000736415_00013 - 0.014 15.2 0.0 0.028 14.3 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Pup PF05639.11 pGCA_000736415_00013 - 0.02 15.8 0.3 0.038 14.9 0.3 1.4 1 0 0 1 1 1 0 Pup-like protein Nbl1_Borealin_N PF10444.9 pGCA_000736415_00013 - 0.047 13.3 2.8 0.37 10.5 0.2 2.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF16 PF01519.16 pGCA_000736415_00013 - 0.16 12.5 3.8 0.41 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-ACC PF17848.1 pGCA_000736415_00016 - 0.0036 17.3 4.1 0.8 9.8 0.4 2.6 2 0 0 2 2 2 2 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 pGCA_000736415_00016 - 0.0069 15.8 2.9 1.8 8.1 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 pGCA_000736415_00016 - 0.0087 15.6 2.4 0.77 9.3 0.4 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding tRNA-synt_1g PF09334.11 pGCA_000736415_00016 - 0.021 13.6 0.7 0.024 13.4 0.7 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-ISL3 PF14690.6 pGCA_000736415_00016 - 0.023 15.4 1.2 0.26 12.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 pGCA_000736415_00016 - 0.031 14.4 0.3 5.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.6 pGCA_000736415_00016 - 0.032 14.0 1.0 6.4 6.6 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pGCA_000736415_00016 - 0.064 13.5 1.4 7.3 6.9 0.0 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Elf1 PF05129.13 pGCA_000736415_00016 - 0.09 12.8 2.1 0.075 13.1 0.9 1.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.6 pGCA_000736415_00016 - 0.09 13.7 1.8 19 6.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3 PF13878.6 pGCA_000736415_00016 - 0.1 12.4 1.6 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF4379 PF14311.6 pGCA_000736415_00016 - 0.13 12.6 6.2 0.49 10.8 1.4 2.6 2 1 0 2 2 2 0 Probable Zinc-ribbon domain DUF35_N PF12172.8 pGCA_000736415_00016 - 0.18 11.7 2.4 5.2 7.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 pGCA_000736415_00016 - 0.22 11.3 4.3 8.6 6.2 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 pGCA_000736415_00016 - 0.25 11.3 4.7 7 6.7 0.2 2.3 1 1 1 2 2 2 0 zinc-ribbon domain CpXC PF14353.6 pGCA_000736415_00016 - 0.25 11.4 2.4 1.2 9.2 2.4 1.9 1 1 0 1 1 1 0 CpXC protein Zn_Tnp_IS91 PF14319.6 pGCA_000736415_00016 - 0.36 10.9 4.1 1 9.4 0.4 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain Zn_Tnp_IS1595 PF12760.7 pGCA_000736415_00016 - 0.66 10.0 5.5 5.1 7.1 3.1 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Phage_integrase PF00589.22 pGCA_000736415_00017 - 4.8e-23 81.8 0.1 8.8e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 pGCA_000736415_00017 - 0.0021 18.5 8.6 0.2 12.1 0.7 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 pGCA_000736415_00017 - 0.0042 17.4 0.3 0.023 15.0 0.3 2.2 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain TSNAXIP1_N PF15739.5 pGCA_000736415_00017 - 0.11 12.8 1.6 0.29 11.5 1.3 1.8 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Phage_int_SAM_3 PF14659.6 pGCA_000736415_00017 - 0.99 9.7 6.9 0.67 10.3 0.7 3.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF1566 PF07603.11 pGCA_000736415_00018 - 0.0015 18.9 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) DUF433 PF04255.14 pGCA_000736415_00019 - 0.047 13.5 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Toxin_YhaV PF11663.8 pGCA_000736415_00019 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system WGR PF05406.15 pGCA_000736415_00023 - 6.7e-07 29.3 0.3 8.8e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 WGR domain DUF3951 PF13131.6 pGCA_000736415_00027 - 0.048 13.9 0.2 0.048 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF4064 PF13273.6 pGCA_000736415_00028 - 1.1 9.6 10.9 2.4e+02 2.1 10.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2929 PF11151.8 pGCA_000736415_00028 - 2.9 8.3 8.4 0.12 12.7 1.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2929) HD_2 PF12917.7 pGCA_000736415_00029 - 0.00032 20.5 0.1 0.00069 19.4 0.1 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme CDT1 PF08839.11 pGCA_000736415_00031 - 0.089 13.1 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like DUF1351 PF07083.11 pGCA_000736415_00032 - 3.8e-24 85.6 8.0 3.8e-24 85.6 8.0 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1351) DUF4337 PF14235.6 pGCA_000736415_00032 - 0.96 9.5 5.4 2.1 8.4 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Allexi_40kDa PF05549.11 pGCA_000736415_00032 - 1.6 8.2 6.9 0.15 11.5 1.9 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein KIP1 PF07765.12 pGCA_000736415_00032 - 8.7 6.5 9.0 0.72 10.0 1.3 2.5 2 0 0 2 2 2 0 KIP1-like protein LBR_tudor PF09465.10 pGCA_000736415_00033 - 0.036 13.9 0.2 0.058 13.2 0.2 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain zf-B_box PF00643.24 pGCA_000736415_00034 - 0.006 16.7 13.5 0.0062 16.7 7.5 2.3 2 0 0 2 2 2 1 B-box zinc finger FYVE PF01363.21 pGCA_000736415_00034 - 0.026 14.6 6.7 0.067 13.3 6.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger DUF4428 PF14471.6 pGCA_000736415_00034 - 0.069 13.1 0.1 0.069 13.1 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.13 pGCA_000736415_00034 - 0.19 11.6 12.5 1.7 8.6 1.0 2.4 2 0 0 2 2 2 0 ClpX C4-type zinc finger Gin PF10764.9 pGCA_000736415_00034 - 0.24 11.4 10.0 3.5 7.7 0.2 2.7 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_2 PF13639.6 pGCA_000736415_00034 - 0.34 11.3 9.3 7.6 7.0 7.4 2.4 1 1 1 2 2 2 0 Ring finger domain zf-CHY PF05495.12 pGCA_000736415_00034 - 0.35 11.4 10.0 0.22 12.0 1.4 2.3 1 1 1 2 2 2 0 CHY zinc finger Ac81 PF05820.11 pGCA_000736415_00034 - 0.92 9.0 4.8 3.3 7.2 2.3 2.1 2 0 0 2 2 2 0 Baculoviridae AC81 zf-C3HC4_3 PF13920.6 pGCA_000736415_00034 - 1.2 9.0 10.5 9.4 6.2 5.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 pGCA_000736415_00034 - 1.5 8.7 13.2 2.1 8.2 6.1 2.5 1 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Tnp_zf-ribbon_2 PF13842.6 pGCA_000736415_00034 - 8.2 7.3 10.6 2.7 8.8 5.2 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-ACC PF17848.1 pGCA_000736415_00037 - 0.098 12.8 3.8 8 6.6 0.5 3.0 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 pGCA_000736415_00037 - 6.7 6.8 10.9 31 4.7 10.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Toprim_2 PF13155.6 pGCA_000736415_00039 - 1e-14 54.7 0.0 2.7e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 Toprim-like Toprim_3 PF13362.6 pGCA_000736415_00039 - 1.6e-08 34.8 0.0 3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.20 pGCA_000736415_00039 - 4.3e-07 29.7 0.3 9.7e-07 28.5 0.3 1.6 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_4 PF13662.6 pGCA_000736415_00039 - 0.0096 16.4 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF3854 PF12965.7 pGCA_000736415_00039 - 0.023 14.7 0.2 0.29 11.1 0.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) N6_N4_Mtase PF01555.18 pGCA_000736415_00040 - 2.4e-05 24.2 0.4 0.042 13.5 0.2 2.1 2 0 0 2 2 2 2 DNA methylase DpnI_C PF17726.1 pGCA_000736415_00040 - 0.00013 22.0 0.3 0.00036 20.6 0.3 1.7 1 0 0 1 1 1 1 Dam-replacing HTH domain zf-BED PF02892.15 pGCA_000736415_00041 - 0.042 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 BED zinc finger DUF4258 PF14076.6 pGCA_000736415_00045 - 0.069 13.5 0.3 0.81 10.1 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) Methyltransf_23 PF13489.6 pGCA_000736415_00045 - 0.15 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MPTase-PolyVal PF18818.1 pGCA_000736415_00046 - 8.2e-48 161.6 0.0 1.2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase superfamily domain DUF1738 PF08401.11 pGCA_000736415_00046 - 1.1e-33 116.1 0.1 1.9e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) EpmC PF04315.12 pGCA_000736415_00046 - 0.00047 19.9 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P hydroxylase Tox-MPTase3 PF15639.6 pGCA_000736415_00046 - 0.0042 16.9 0.1 0.0092 15.8 0.1 1.5 1 0 0 1 1 1 1 Metallopeptidase toxin 3 DUF4127 PF13552.6 pGCA_000736415_00046 - 0.021 13.5 0.1 0.028 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) GP88 PF17338.2 pGCA_000736415_00046 - 0.022 14.2 0.1 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 Gene product 88 Fucose_iso_N2 PF07882.12 pGCA_000736415_00047 - 0.0057 16.2 0.8 0.01 15.5 0.3 1.6 1 1 1 2 2 2 1 L-fucose isomerase, second N-terminal domain RNA_pol_Rpb8 PF03870.15 pGCA_000736415_00047 - 0.056 13.6 0.1 0.076 13.2 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb8 s48_45 PF07422.13 pGCA_000736415_00047 - 0.082 13.5 0.8 0.28 11.8 0.1 1.8 1 1 0 2 2 2 0 Sexual stage antigen s48/45 domain RecT PF03837.14 pGCA_000736415_00048 - 1.2e-36 126.1 0.3 4.5e-36 124.2 0.0 1.8 1 1 1 2 2 2 1 RecT family Cas_Cas4 PF01930.17 pGCA_000736415_00051 - 1.6e-06 28.3 0.2 1.6e-06 28.3 0.2 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 pGCA_000736415_00051 - 8.1e-05 22.7 1.2 0.00013 22.0 0.2 1.9 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Nsp1_C PF05064.13 pGCA_000736415_00051 - 0.0026 17.5 0.5 0.0026 17.5 0.5 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region GrpE PF01025.19 pGCA_000736415_00051 - 0.011 15.4 1.7 0.011 15.4 1.7 2.3 2 0 0 2 2 2 0 GrpE CENP-F_leu_zip PF10473.9 pGCA_000736415_00051 - 0.035 14.1 9.6 0.043 13.8 3.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 pGCA_000736415_00051 - 0.058 12.7 1.6 0.1 11.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CdvA PF18822.1 pGCA_000736415_00051 - 0.2 11.5 8.1 1.2 8.9 1.2 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF615 PF04751.14 pGCA_000736415_00051 - 1.7 8.6 7.9 0.17 11.8 1.5 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF615) CHASE3 PF05227.13 pGCA_000736415_00051 - 6.7 6.6 8.3 1.5 8.7 0.7 2.7 3 0 0 3 3 3 0 CHASE3 domain SSB PF00436.25 pGCA_000736415_00053 - 1.8e-29 101.9 0.2 3.2e-29 101.0 0.2 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Pex14_N PF04695.13 pGCA_000736415_00053 - 0.29 11.8 7.3 0.46 11.1 7.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Toxin-JAB1 PF15659.6 pGCA_000736415_00054 - 0.088 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 JAB-like toxin 1 Dus PF01207.17 pGCA_000736415_00058 - 0.03 13.4 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) SLT PF01464.20 pGCA_000736415_00059 - 4.6e-19 68.2 0.0 6.1e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 pGCA_000736415_00059 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family DUF480 PF04337.12 pGCA_000736415_00060 - 0.0017 18.4 0.1 0.0019 18.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF480 RdRP_1 PF00680.20 pGCA_000736415_00060 - 0.027 13.0 0.1 0.03 12.8 0.1 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF3267 PF11667.8 pGCA_000736415_00061 - 0.042 14.1 8.6 0.053 13.8 5.1 2.6 1 1 1 2 2 2 0 Putative zincin peptidase Peptidase_M50B PF13398.6 pGCA_000736415_00061 - 0.14 11.8 7.8 2.4 7.7 7.7 2.3 1 1 0 1 1 1 0 Peptidase M50B-like GGDEF PF00990.21 pGCA_000736415_00062 - 5e-34 117.4 0.6 1.1e-33 116.2 0.6 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HD PF01966.22 pGCA_000736415_00062 - 2.7e-05 24.4 0.4 2.7e-05 24.4 0.4 3.0 4 0 0 4 4 4 1 HD domain SporV_AA PF12164.8 pGCA_000736415_00062 - 0.039 14.3 4.1 0.057 13.8 0.2 3.1 3 0 0 3 3 3 0 Stage V sporulation protein AA STAR_dimer PF16544.5 pGCA_000736415_00062 - 0.044 13.4 0.3 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Toxin-deaminase PF14424.6 pGCA_000736415_00062 - 0.045 13.9 0.6 0.045 13.9 0.6 3.2 3 0 0 3 3 3 0 The BURPS668_1122 family of deaminases Stealth_CR4 PF17103.5 pGCA_000736415_00062 - 0.081 12.8 0.1 6.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 SurA_N_2 PF13623.6 pGCA_000736415_00062 - 4.1 7.3 12.7 2.3 8.1 0.5 3.8 4 0 0 4 4 4 0 SurA N-terminal domain TrwB_AAD_bind PF10412.9 pGCA_000736415_00063 - 5.1e-16 58.6 0.0 1.7e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 pGCA_000736415_00063 - 2e-11 43.4 0.6 2.8e-11 42.9 0.6 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_000736415_00063 - 4.3e-10 39.7 0.0 8.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG DUF87 PF01935.17 pGCA_000736415_00063 - 0.0005 20.2 0.3 0.0045 17.1 0.3 2.3 1 1 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 pGCA_000736415_00063 - 0.0014 17.9 0.0 0.0035 16.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 pGCA_000736415_00063 - 0.0017 18.8 0.0 0.0043 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 pGCA_000736415_00063 - 0.0022 18.0 0.0 0.01 15.8 0.0 2.1 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea DUF853 PF05872.12 pGCA_000736415_00063 - 0.0045 15.6 0.0 0.0082 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_10 PF12846.7 pGCA_000736415_00063 - 0.0054 15.7 0.1 0.12 11.2 0.0 2.4 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.6 pGCA_000736415_00063 - 0.011 16.1 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 pGCA_000736415_00063 - 0.095 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 pGCA_000736415_00063 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain HD_5 PF13487.6 pGCA_000736415_00064 - 4.6e-06 26.8 0.0 8.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 HD domain CLP_protease PF00574.23 pGCA_000736415_00066 - 0.15 12.0 0.3 0.3 10.9 0.3 1.5 1 0 0 1 1 1 0 Clp protease GA-like PF17573.2 pGCA_000736415_00067 - 0.035 14.0 0.4 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 GA-like domain Orthopox_A49R PF06489.11 pGCA_000736415_00067 - 0.16 12.2 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A49R protein HTH_3 PF01381.22 pGCA_000736415_00068 - 2.7e-14 52.9 0.0 3.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pGCA_000736415_00068 - 7.9e-13 48.2 0.0 8.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 pGCA_000736415_00068 - 8.3e-08 32.5 0.0 8.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 pGCA_000736415_00068 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_CI_repr PF07022.13 pGCA_000736415_00068 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.3 1 1 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain Pou PF00157.17 pGCA_000736415_00068 - 0.026 14.5 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_37 PF13744.6 pGCA_000736415_00068 - 0.047 13.7 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 pGCA_000736415_00068 - 0.055 13.6 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_23 PF13384.6 pGCA_000736415_00068 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain WYL_3 PF18488.1 pGCA_000736415_00068 - 0.081 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 WYL domain YdaS_antitoxin PF15943.5 pGCA_000736415_00068 - 0.1 12.4 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SNase PF00565.17 pGCA_000736415_00069 - 4.4e-17 62.5 0.1 5.5e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue AAA_25 PF13481.6 pGCA_000736415_00072 - 5.9e-17 61.9 0.0 9.6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB PF00772.21 pGCA_000736415_00072 - 1.3e-06 28.4 0.3 2.9e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain Thioredoxin_2 PF13098.6 pGCA_000736415_00073 - 2.7e-05 24.6 0.2 0.00022 21.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 pGCA_000736415_00073 - 3.2e-05 24.0 0.0 4.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 pGCA_000736415_00073 - 0.00012 22.1 0.1 0.0003 20.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF255 VSG_B PF13206.6 pGCA_000736415_00074 - 0.018 14.3 0.9 0.018 14.3 0.9 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain HSCB_C PF07743.13 pGCA_000736415_00074 - 0.019 15.5 2.0 0.021 15.3 2.0 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain YtxH PF12732.7 pGCA_000736415_00074 - 0.034 14.7 0.1 0.045 14.3 0.1 1.2 1 0 0 1 1 1 0 YtxH-like protein TrbC_Ftype PF09673.10 pGCA_000736415_00075 - 9.3e-17 61.1 0.0 2.2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein DUF3388 PF11868.8 pGCA_000736415_00075 - 0.035 13.4 0.2 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) EAL PF00563.20 pGCA_000736415_00076 - 3.4e-28 98.8 0.0 4.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 EAL domain TraU PF06834.11 pGCA_000736415_00077 - 8.2e-100 334.0 0.4 9.4e-100 333.8 0.4 1.0 1 0 0 1 1 1 1 TraU protein TraF PF13728.6 pGCA_000736415_00079 - 3e-30 105.7 10.7 3.5e-30 105.5 10.7 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein KaiB PF07689.12 pGCA_000736415_00079 - 0.055 13.2 0.2 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 KaiB domain ASC PF00858.24 pGCA_000736415_00079 - 0.72 8.7 5.6 0.91 8.4 5.6 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TraG_N PF07916.11 pGCA_000736415_00080 - 1.7e-51 175.6 17.8 1.7e-51 175.6 17.8 2.8 3 0 0 3 3 3 1 TraG-like protein, N-terminal region CdiI_2 PF18593.1 pGCA_000736415_00080 - 0.18 12.5 0.8 11 6.7 0.4 2.9 1 1 1 2 2 2 0 CdiI immunity protein YfhO PF09586.10 pGCA_000736415_00081 - 0.016 13.5 2.6 0.018 13.3 2.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1189 PF06691.11 pGCA_000736415_00081 - 0.017 14.7 2.0 0.02 14.5 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) Herpes_LMP1 PF05297.11 pGCA_000736415_00081 - 0.068 12.4 3.2 0.083 12.1 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RHH_3 PF12651.7 pGCA_000736415_00082 - 0.0013 18.6 1.3 0.0028 17.6 0.8 1.8 2 0 0 2 2 2 1 Ribbon-helix-helix domain DUF5123 PF17161.4 pGCA_000736415_00082 - 0.058 14.5 0.9 0.068 14.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5123) UvrB_inter PF17757.1 pGCA_000736415_00083 - 0.052 13.7 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 UvrB interaction domain ALP_N PF17989.1 pGCA_000736415_00085 - 5.9e-15 55.7 0.1 1.1e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Actin like proteins N terminal domain FtsA PF14450.6 pGCA_000736415_00085 - 0.00012 22.5 0.1 0.031 14.7 0.0 2.4 2 0 0 2 2 2 2 Cell division protein FtsA DUF2800 PF10926.8 pGCA_000736415_00085 - 0.12 11.6 0.1 0.37 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) DBR1 PF05011.13 pGCA_000736415_00086 - 0.0072 16.8 1.1 0.0081 16.6 1.1 1.1 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain DUF3400 PF11880.8 pGCA_000736415_00087 - 0.1 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) DUF2786 PF10979.8 pGCA_000736415_00087 - 0.18 11.8 1.3 0.37 10.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Acetyltransf_9 PF13527.7 pGCA_000736415_00088 - 0.099 12.7 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ring_hydroxyl_B PF00866.18 pGCA_000736415_00089 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit SSXT PF05030.12 pGCA_000736415_00090 - 0.022 14.4 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 SSXT protein (N-terminal region) NMT PF01233.19 pGCA_000736415_00090 - 0.092 12.6 0.6 0.11 12.3 0.6 1.5 1 1 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain bZIP_2 PF07716.15 pGCA_000736415_00090 - 0.13 12.4 0.3 0.13 12.4 0.3 1.6 2 0 0 2 2 2 0 Basic region leucine zipper BfiI_DBD PF18243.1 pGCA_000736415_00090 - 0.17 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain AbiH PF14253.6 pGCA_000736415_00092 - 0.023 14.6 1.3 0.03 14.2 1.3 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH PH_12 PF16457.5 pGCA_000736415_00092 - 0.1 13.1 0.2 0.83 10.2 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain ANT PF03374.14 pGCA_000736415_00093 - 0.041 14.2 0.0 0.045 14.1 0.0 1.1 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain PhetRS_B1 PF18262.1 pGCA_000736415_00093 - 0.062 13.5 0.2 0.076 13.2 0.2 1.1 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain HTH_28 PF13518.6 pGCA_000736415_00093 - 0.1 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TMEM51 PF15345.6 pGCA_000736415_00094 - 0.11 12.3 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_19 PF13245.6 pGCA_000736415_00095 - 2.8e-13 50.4 0.0 7.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 pGCA_000736415_00095 - 4.2e-13 49.5 7.9 3.8e-08 33.2 2.3 3.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 pGCA_000736415_00095 - 3.2e-12 46.5 2.8 1.2e-11 44.7 1.9 2.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 pGCA_000736415_00095 - 5.1e-09 35.8 0.0 2.9e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 pGCA_000736415_00095 - 1.1e-08 35.1 0.7 0.0055 16.5 0.0 3.5 2 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 pGCA_000736415_00095 - 0.00014 21.6 0.1 0.0023 17.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 pGCA_000736415_00095 - 0.00093 18.7 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 pGCA_000736415_00095 - 0.011 15.7 5.8 0.027 14.5 1.5 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 pGCA_000736415_00095 - 0.017 15.0 0.3 6.1 6.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain OMPdecase PF00215.24 pGCA_000736415_00095 - 0.11 12.1 0.1 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family RNase_T PF00929.24 pGCA_000736415_00097 - 0.036 14.6 0.1 0.04 14.4 0.1 1.1 1 0 0 1 1 1 0 Exonuclease DUF1722 PF08349.11 pGCA_000736415_00098 - 0.11 12.8 0.0 0.13 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF460 PF04312.13 pGCA_000736415_00100 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF5643 PF18705.1 pGCA_000736415_00103 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5643) MrpF_PhaF PF04066.13 pGCA_000736415_00106 - 0.01 16.2 1.3 0.01 16.2 1.3 2.5 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) UPF0242 PF06785.11 pGCA_000736415_00106 - 0.026 14.6 1.1 0.028 14.5 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UPF0016 PF01169.19 pGCA_000736415_00106 - 0.039 14.3 7.1 0.089 13.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein family UPF0016 TrbC PF04956.13 pGCA_000736415_00106 - 1.2 9.4 11.4 1.3 9.3 11.4 1.0 1 0 0 1 1 1 0 TrbC/VIRB2 family TraL PF07178.11 pGCA_000736415_00107 - 2.4e-12 47.2 1.0 2.7e-12 47.0 1.0 1.1 1 0 0 1 1 1 1 TraL protein ThrE PF06738.12 pGCA_000736415_00107 - 0.024 14.0 0.3 0.026 13.9 0.3 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter TraE PF05309.11 pGCA_000736415_00108 - 2e-34 118.5 1.7 2.5e-34 118.3 1.7 1.0 1 0 0 1 1 1 1 TraE protein MadM PF03818.13 pGCA_000736415_00108 - 0.047 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit TraK PF06586.11 pGCA_000736415_00109 - 9.5e-24 84.4 3.7 3.6e-23 82.5 3.7 1.7 1 1 0 1 1 1 1 TraK protein NusG_II PF07009.11 pGCA_000736415_00109 - 0.32 11.2 4.5 0.13 12.4 0.6 2.2 2 1 0 2 2 2 0 NusG domain II TrbI PF03743.14 pGCA_000736415_00110 - 3.5e-33 115.0 1.1 4.8e-33 114.6 1.1 1.2 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein Bap31_Bap29_C PF18035.1 pGCA_000736415_00110 - 0.0036 17.3 1.3 0.011 15.7 1.3 1.8 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 pGCA_000736415_00110 - 0.0052 17.0 2.6 0.01 16.0 2.6 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 pGCA_000736415_00110 - 0.0093 16.1 2.9 0.027 14.6 2.9 1.8 1 0 0 1 1 1 1 bZIP transcription factor UPF0242 PF06785.11 pGCA_000736415_00110 - 0.046 13.8 1.5 0.083 13.0 1.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 pGCA_000736415_00110 - 0.094 12.5 3.1 0.23 11.2 3.1 1.6 1 0 0 1 1 1 0 Septum formation initiator FAD-SLDH PF12318.8 pGCA_000736415_00110 - 0.13 12.3 0.8 0.26 11.3 0.2 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase YabA PF06156.13 pGCA_000736415_00110 - 0.19 12.4 1.5 0.48 11.1 1.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Thioredoxin_2 PF13098.6 pGCA_000736415_00111 - 3.3e-16 59.7 0.1 6.6e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 pGCA_000736415_00111 - 1.3e-07 30.9 0.1 3e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 pGCA_000736415_00111 - 1.3e-06 28.7 2.0 0.0038 17.4 0.3 3.2 1 1 1 2 2 2 2 Thioredoxin DSBA PF01323.20 pGCA_000736415_00111 - 1.3e-06 28.3 0.3 0.01 15.6 0.1 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 pGCA_000736415_00111 - 0.0039 17.4 0.3 0.038 14.2 0.1 2.4 2 0 0 2 2 2 1 Glutaredoxin ATPgrasp_YheCD PF14398.6 pGCA_000736415_00111 - 0.0088 15.3 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp TraF PF13728.6 pGCA_000736415_00111 - 0.013 15.3 0.1 6.2 6.6 0.0 2.4 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 pGCA_000736415_00111 - 0.021 14.9 1.1 9.8 6.3 0.4 2.8 2 1 1 3 3 3 0 Thioredoxin domain Thioredoxin_8 PF13905.6 pGCA_000736415_00111 - 0.04 14.2 0.4 0.18 12.1 0.4 2.1 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.6 pGCA_000736415_00111 - 0.071 12.8 0.4 6.9 6.3 0.4 2.3 1 1 1 2 2 2 0 Thioredoxin TraV PF09676.10 pGCA_000736415_00112 - 0.0043 18.0 5.3 0.0097 16.9 5.2 1.8 1 1 0 1 1 1 1 Type IV conjugative transfer system lipoprotein (TraV) SH3_4 PF06347.13 pGCA_000736415_00112 - 0.0063 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_3 PF08239.11 pGCA_000736415_00112 - 0.013 15.7 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Transketolase_N PF00456.21 pGCA_000736415_00112 - 0.049 12.6 0.3 0.085 11.8 0.3 1.5 1 1 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Herpes_glycop_D PF01537.17 pGCA_000736415_00112 - 0.052 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain SH3_3 PF08239.11 pGCA_000736415_00113 - 5.6e-05 23.3 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain ADIP PF11559.8 pGCA_000736415_00113 - 0.0013 18.8 3.7 0.0023 18.0 3.7 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 pGCA_000736415_00113 - 0.0038 17.1 1.5 0.0054 16.6 1.5 1.3 1 0 0 1 1 1 1 Sec34-like family CLZ PF16526.5 pGCA_000736415_00113 - 0.0068 16.7 4.4 1.8 9.0 0.0 2.4 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SMC_ScpB PF04079.16 pGCA_000736415_00113 - 0.0085 15.7 1.4 0.013 15.2 1.4 1.3 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB V_ATPase_I PF01496.19 pGCA_000736415_00113 - 0.022 12.7 3.4 0.025 12.5 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 pGCA_000736415_00113 - 0.03 14.7 0.6 0.045 14.1 0.6 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Cob_adeno_trans PF01923.18 pGCA_000736415_00113 - 0.041 14.0 1.6 0.067 13.3 1.6 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Spectrin PF00435.21 pGCA_000736415_00113 - 0.046 14.2 2.7 0.11 13.0 2.7 1.6 1 0 0 1 1 1 0 Spectrin repeat M PF02370.16 pGCA_000736415_00113 - 0.072 13.7 6.6 0.31 11.7 6.6 2.2 1 0 0 1 1 1 0 M protein repeat DUF1319 PF07028.11 pGCA_000736415_00113 - 0.11 12.7 3.3 0.23 11.7 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) TolA_bind_tri PF16331.5 pGCA_000736415_00113 - 0.16 12.0 2.2 0.53 10.4 1.7 2.0 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF272 PF03312.15 pGCA_000736415_00113 - 0.2 11.9 3.6 1.6 9.0 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF272) FlaC_arch PF05377.11 pGCA_000736415_00113 - 0.24 11.8 4.0 2 8.9 1.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 pGCA_000736415_00113 - 0.27 11.7 2.6 0.55 10.7 1.7 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 pGCA_000736415_00113 - 0.67 9.9 6.4 0.83 9.6 3.3 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 pGCA_000736415_00113 - 1.6 9.4 7.4 2.7 8.7 7.4 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Swi5 PF07061.11 pGCA_000736415_00113 - 5.2 7.2 8.9 1.3 9.1 3.1 2.5 2 1 1 3 3 3 0 Swi5 TrbC PF04956.13 pGCA_001417635_00002 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_001417635_00002 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pGCA_001417635_00004 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_001417635_00004 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pGCA_001417635_00005 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_001417635_00005 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_001417635_00005 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_001417635_00005 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pGCA_001417635_00006 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001417635_00006 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001417635_00006 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_001417635_00006 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_001417635_00006 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_001417635_00006 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_001417635_00006 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 pGCA_001417635_00007 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pGCA_001417635_00009 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pGCA_001417635_00009 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pGCA_001417635_00009 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 pGCA_001417635_00010 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pGCA_001417635_00010 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pGCA_001417635_00010 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pGCA_001417635_00010 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 pGCA_001417635_00011 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pGCA_001417635_00011 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pGCA_001417635_00012 - 2.3e-08 34.3 0.0 4.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_001417635_00012 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_001417635_00012 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_001417635_00012 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pGCA_001417635_00013 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 pGCA_001417635_00015 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pGCA_001417635_00015 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pGCA_001417635_00015 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pGCA_001417635_00016 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_001417635_00016 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_001417635_00016 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pGCA_001417635_00016 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pGCA_001417635_00016 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pGCA_001417635_00017 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain Acetyltransf_7 PF13508.7 pGCA_001417635_00018 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_001417635_00018 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family SNF2_N PF00176.23 pGCA_001417635_00019 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_001417635_00019 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_001417635_00019 - 9.8e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_001417635_00019 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_001417635_00019 - 2.9e-05 24.5 0.6 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pGCA_001417635_00020 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pGCA_001417635_00021 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001417635_00021 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001417635_00021 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_001417635_00021 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_001417635_00021 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pGCA_001417635_00022 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_001417635_00022 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pGCA_001417635_00023 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_001417635_00023 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_001417635_00023 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_001417635_00023 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_001417635_00023 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pGCA_001417635_00024 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_001417635_00024 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_001417635_00024 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_001417635_00024 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_001417635_00024 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_001417635_00024 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_001417635_00024 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pGCA_001417635_00025 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 pGCA_001417635_00026 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_001417635_00026 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pGCA_001417635_00027 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon APH PF01636.23 pGCA_001417635_00028 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pGCA_001417635_00028 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pGCA_001417635_00028 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family GTP_EFTU PF00009.27 pGCA_001417635_00029 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_001417635_00029 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_001417635_00029 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_001417635_00029 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_001417635_00029 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_001417635_00029 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_001417635_00029 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_001417635_00029 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_001417635_00029 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pGCA_001417635_00031 - 5.2e-05 23.2 2.2 0.00013 21.8 2.2 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_001417635_00031 - 0.022 14.7 4.0 0.032 14.2 1.5 2.5 1 1 1 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 pGCA_001417635_00032 - 9.9e-97 324.5 8.2 1.4e-96 324.1 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_001417635_00032 - 1.4e-12 47.7 0.4 9.1e-12 45.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zinc_ribbon_9 PF14369.6 pGCA_001417635_00032 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 pGCA_001417635_00032 - 0.057 13.2 2.4 0.16 11.8 2.4 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger EF-hand_8 PF13833.6 pGCA_001417635_00032 - 0.077 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pGCA_001417635_00032 - 0.27 11.4 2.9 0.78 10.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain Redoxin PF08534.10 pGCA_001417635_00033 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pGCA_001417635_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_001417635_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_001417635_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pGCA_001417635_00036 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pGCA_001417635_00037 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_001417635_00037 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_001417635_00037 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_001417635_00037 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pGCA_001417635_00038 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_001417635_00038 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_001417635_00038 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_001417635_00038 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pGCA_001417635_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_001417635_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_001417635_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_001417635_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_001417635_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_001417635_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_001417635_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_001417635_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_001417635_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_001417635_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_001417635_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_001417635_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_001417635_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_001417635_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_001417635_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_001417635_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_001417635_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_001417635_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_001417635_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_001417635_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_001417635_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_001417635_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_001417635_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_001417635_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_001417635_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_001417635_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_001417635_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_001417635_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_001417635_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_001417635_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_001417635_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pGCA_001417635_00040 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_001417635_00040 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pGCA_001417635_00041 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_001417635_00041 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pGCA_001417635_00042 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_001417635_00042 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pGCA_001417635_00043 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_001417635_00043 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pGCA_001417635_00044 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_001417635_00044 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_001417635_00044 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pGCA_001417635_00045 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_001417635_00045 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_001417635_00045 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pGCA_001417635_00045 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pGCA_001417635_00045 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pGCA_001417635_00045 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pGCA_001417635_00045 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pGCA_001417635_00045 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pGCA_001417635_00046 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_001417635_00046 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_001417635_00046 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_001417635_00046 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pGCA_001417635_00047 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 pGCA_001417635_00048 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pGCA_001417635_00048 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pGCA_001417635_00048 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pGCA_001417635_00048 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pGCA_001417635_00048 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pGCA_001417635_00048 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 pGCA_001417635_00049 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pGCA_001417635_00049 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pGCA_001417635_00049 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pGCA_001417635_00049 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pGCA_001417635_00049 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pGCA_001417635_00050 - 2e-06 28.0 0.4 5.3e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 CagE, TrbE, VirB family, component of type IV transporter system AAA_10 PF12846.7 pGCA_001417635_00050 - 7.4e-06 25.1 1.2 2e-05 23.7 1.2 1.6 1 1 0 1 1 1 1 AAA-like domain HNOBA PF07701.14 pGCA_001417635_00050 - 0.017 14.6 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 pGCA_001417635_00050 - 0.2 11.6 0.0 0.47 10.4 0.0 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like T6SS-SciN PF12790.7 pGCA_001563565_00001 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pGCA_001563565_00002 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pGCA_001563565_00003 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pGCA_001563565_00004 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pGCA_001563565_00005 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pGCA_001563565_00005 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pGCA_001563565_00005 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pGCA_001563565_00005 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pGCA_001563565_00005 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pGCA_001563565_00005 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pGCA_001563565_00005 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pGCA_001563565_00006 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pGCA_001563565_00006 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pGCA_001563565_00006 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF2974 PF11187.8 pGCA_001563565_00010 - 3.9e-08 33.1 0.1 1e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 pGCA_001563565_00010 - 6.3e-08 32.6 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 pGCA_001563565_00010 - 3.1e-05 23.6 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pGCA_001563565_00010 - 4.2e-05 23.4 0.4 0.00085 19.1 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 pGCA_001563565_00010 - 0.00084 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pGCA_001563565_00010 - 0.0016 19.1 0.0 0.0022 18.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pGCA_001563565_00010 - 0.0033 17.4 0.1 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 pGCA_001563565_00010 - 0.036 13.6 1.9 0.045 13.3 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4450) SBDS PF01172.18 pGCA_001563565_00010 - 0.11 12.6 1.6 0.82 9.8 1.5 2.7 1 1 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Lipase_3 PF01764.25 pGCA_001563565_00012 - 1.5e-08 34.6 0.0 5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pGCA_001563565_00012 - 3.1e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pGCA_001563565_00012 - 1.1e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pGCA_001563565_00012 - 5.6e-05 23.0 0.1 9.7e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 pGCA_001563565_00012 - 0.00041 20.0 0.1 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pGCA_001563565_00012 - 0.00064 20.4 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pGCA_001563565_00012 - 0.0014 18.6 0.3 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 pGCA_001563565_00012 - 0.014 15.3 1.8 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase NMT PF01233.19 pGCA_001563565_00012 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Hydrolase_4 PF12146.8 pGCA_001563565_00012 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 pGCA_001563565_00012 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF2070 PF09843.9 pGCA_001563565_00013 - 0.082 11.2 10.5 0.094 11.0 10.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 pGCA_001563565_00013 - 0.094 13.1 17.4 0.35 11.2 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 pGCA_001563565_00013 - 0.2 11.0 22.9 4.3 6.6 6.7 2.4 1 1 1 2 2 2 0 Glucosyl transferase GtrII ABC2_membrane_5 PF13346.6 pGCA_001563565_00013 - 0.31 10.5 21.7 0.023 14.2 5.5 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF5385 PF17359.2 pGCA_001563565_00013 - 0.4 10.2 9.3 0.085 12.4 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF3784 PF12650.7 pGCA_001563565_00013 - 4.8 7.4 22.3 0.22 11.7 8.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) RseC_MucC PF04246.12 pGCA_001563565_00014 - 9.1 6.3 6.3 2.4 8.1 3.1 1.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AAA_31 PF13614.6 pGCA_001563565_00016 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001563565_00016 - 0.0018 18.3 0.5 0.016 15.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001563565_00016 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pGCA_001563565_00017 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pGCA_001563565_00017 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal OrfB_IS605 PF01385.19 pGCA_001563565_00018 - 1.8e-12 47.5 1.0 2.5e-12 47.1 1.0 1.2 1 0 0 1 1 1 1 Probable transposase AAA_25 PF13481.6 pGCA_001563565_00019 - 2.9e-15 56.3 0.0 6.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001563565_00019 - 0.00024 20.5 0.0 0.01 15.2 0.0 2.4 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001563565_00019 - 0.0012 18.6 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pGCA_001563565_00019 - 0.0029 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pGCA_001563565_00019 - 0.0041 16.5 0.1 0.03 13.7 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pGCA_001563565_00019 - 0.053 13.9 0.8 0.67 10.4 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pGCA_001563565_00019 - 0.16 12.1 0.8 0.49 10.5 0.8 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicA_toxin PF07927.12 pGCA_001563565_00020 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pGCA_001563565_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Peptidase_M4_C PF02868.15 pGCA_001563565_00022 - 0.051 13.4 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain AAA_31 PF13614.6 pGCA_001563565_00025 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001563565_00025 - 0.0018 18.3 0.5 0.016 15.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001563565_00025 - 0.014 14.9 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pGCA_001563565_00026 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pGCA_001563565_00026 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal NYN PF01936.18 pGCA_001563565_00028 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pGCA_001563565_00028 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pGCA_001563565_00028 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain Toprim_3 PF13362.6 pGCA_001563565_00030 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pGCA_001563565_00030 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pGCA_001563565_00030 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pGCA_001563565_00030 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Put_DNA-bind_N PF06971.13 pGCA_001563565_00032 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus BLOC1_2 PF10046.9 pGCA_001563565_00033 - 0.049 13.9 1.0 0.25 11.7 1.0 2.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2459 PF09601.10 pGCA_001563565_00033 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) SseC PF04888.12 pGCA_001563565_00036 - 0.005 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 pGCA_001563565_00036 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pGCA_001563565_00036 - 0.036 14.0 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 pGCA_001563565_00036 - 0.061 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UvrA_DNA-bind PF17755.1 pGCA_001563565_00037 - 0.008 16.5 0.4 2.8 8.3 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain Glyco_tranf_2_5 PF13712.6 pGCA_001563565_00038 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 pGCA_001563565_00039 - 1.5e-38 132.9 22.2 1.5e-38 132.9 22.2 2.3 2 1 1 3 3 3 1 TraG-like protein, N-terminal region CHMI PF02962.15 pGCA_001563565_00039 - 0.0083 16.5 0.0 0.057 13.8 0.0 2.6 1 1 0 1 1 1 1 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 pGCA_001563565_00041 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pGCA_001563565_00041 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 pGCA_001563565_00041 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 pGCA_001563565_00041 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 pGCA_001563565_00043 - 8.6e-09 35.6 0.3 0.00036 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pGCA_001563565_00043 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 pGCA_001563565_00044 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 pGCA_001563565_00046 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 pGCA_001563565_00046 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein Pox_J1 PF03338.15 pGCA_001563565_00047 - 0.0028 17.5 1.7 0.096 12.5 0.1 2.5 2 1 0 2 2 2 2 Poxvirus J1 protein DHHA1 PF02272.19 pGCA_001563565_00047 - 0.85 10.0 3.4 1.7 9.1 3.2 1.6 1 1 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 pGCA_001563565_00048 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 pGCA_001563565_00049 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pGCA_001563565_00049 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pGCA_001563565_00049 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 pGCA_001563565_00051 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 pGCA_001563565_00051 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 pGCA_001563565_00052 - 7.5e-25 87.7 1.9 1.4e-24 86.8 0.2 2.2 2 1 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.8 pGCA_001563565_00052 - 0.00023 21.3 0.1 0.0011 19.2 0.1 2.2 2 0 0 2 2 2 1 IMS family HHH motif CooC_C PF15976.5 pGCA_001563565_00054 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 pGCA_001563565_00054 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 pGCA_001563565_00055 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pGCA_001563565_00055 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pGCA_001563565_00055 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pGCA_001563565_00055 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 pGCA_001563565_00055 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 pGCA_001563565_00055 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pGCA_001563565_00055 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pGCA_001563565_00055 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pGCA_001563565_00055 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pGCA_001563565_00055 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pGCA_001563565_00055 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pGCA_001563565_00055 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pGCA_001563565_00055 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 pGCA_001563565_00055 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 pGCA_001563565_00055 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 pGCA_001563565_00055 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 pGCA_001563565_00055 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 pGCA_001563565_00055 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pGCA_001563565_00055 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pGCA_001563565_00055 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 pGCA_001563565_00057 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 pGCA_001563565_00057 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Occludin_ELL PF07303.13 pGCA_001563565_00060 - 0.0057 17.4 1.0 0.0076 17.0 1.0 1.1 1 0 0 1 1 1 1 Occludin homology domain DUF2935 PF11155.8 pGCA_001563565_00060 - 0.019 15.3 1.9 0.023 15.0 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) HAUS4 PF14735.6 pGCA_001563565_00060 - 0.038 13.7 0.1 0.044 13.5 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF2207 PF09972.9 pGCA_001563565_00060 - 0.19 10.5 2.4 0.2 10.4 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_NinH PF06322.11 pGCA_001563565_00061 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein YafQ_toxin PF15738.5 pGCA_001563565_00065 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pGCA_001563565_00065 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 pGCA_001563565_00065 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 pGCA_001563565_00065 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system WGR PF05406.15 pGCA_001563565_00070 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pGCA_001563565_00070 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 pGCA_001563565_00071 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 pGCA_001563565_00072 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pGCA_001563565_00072 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pGCA_001563565_00072 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pGCA_001563565_00072 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 pGCA_001563565_00072 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 pGCA_001563565_00072 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 pGCA_001563565_00072 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Prok-TraM PF09228.10 pGCA_001563565_00074 - 0.087 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 pGCA_001563565_00074 - 2.3 8.5 10.7 0.22 11.8 0.4 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 pGCA_001563565_00075 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 pGCA_001563565_00076 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pGCA_001563565_00076 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pGCA_001563565_00076 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 pGCA_001563565_00078 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pGCA_001563565_00078 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 pGCA_001563565_00080 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 pGCA_001563565_00082 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 pGCA_001563565_00082 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 pGCA_001563565_00082 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 pGCA_001563565_00084 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 pGCA_001563565_00085 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 pGCA_001563565_00085 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 pGCA_001563565_00085 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 pGCA_001563565_00085 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myc-LZ PF02344.15 pGCA_001563565_00086 - 0.045 13.9 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Myc leucine zipper domain Importin_rep PF18773.1 pGCA_001563565_00087 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 pGCA_001563565_00087 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 pGCA_001563565_00087 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 pGCA_001563565_00088 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pGCA_001563565_00088 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pGCA_001563565_00089 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pGCA_001563565_00090 - 1.6e-110 370.4 0.0 1.8e-110 370.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pGCA_001563565_00091 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pGCA_001563565_00091 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pGCA_001563565_00091 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pGCA_001563565_00092 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pGCA_001563565_00092 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pGCA_001563565_00093 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pGCA_001563565_00093 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pGCA_001563565_00094 - 2.9e-12 46.6 0.0 4.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pGCA_001563565_00094 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system TetR_C_24 PF17932.1 pGCA_001563565_00094 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PX PF00787.24 pGCA_001563565_00094 - 0.28 11.2 14.0 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain Prok-TraM PF09228.10 pGCA_001587035_00001 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Flu_B_M2 PF04772.12 pGCA_001587035_00001 - 3 8.1 11.1 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Influenza B matrix protein 2 (BM2) TagA PF12561.8 pGCA_001587035_00002 - 1.1 9.7 3.4 17 5.9 0.7 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain DUF4299 PF14132.6 pGCA_001587035_00003 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pGCA_001587035_00003 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pGCA_001587035_00003 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region AHH PF14412.6 pGCA_001587035_00005 - 5.3e-16 58.7 1.4 9.6e-16 57.9 1.4 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pGCA_001587035_00005 - 0.12 12.3 4.7 0.16 11.9 0.1 2.4 2 0 0 2 2 2 0 Ribosome recycling factor Glyco_hydro_59 PF02057.15 pGCA_001587035_00007 - 0.022 14.0 1.2 0.043 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Nucleoside_tran PF01733.18 pGCA_001587035_00009 - 0.15 11.4 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 Nucleoside transporter Turandot PF07240.11 pGCA_001587035_00009 - 0.19 11.7 1.3 0.48 10.4 0.6 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Sigma70_ner PF04546.13 pGCA_001587035_00009 - 0.2 11.5 6.4 0.1 12.4 1.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Rapsyn_N PF10579.9 pGCA_001587035_00011 - 0.53 10.4 3.8 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF2768 PF10966.8 pGCA_001587035_00012 - 0.0086 16.5 0.2 0.0086 16.5 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2768) DiS_P_DiS PF06750.13 pGCA_001587035_00012 - 0.027 14.6 0.4 0.054 13.6 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DZR PF12773.7 pGCA_001587035_00012 - 0.028 14.4 0.3 0.037 14.0 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 pGCA_001587035_00012 - 0.14 12.1 4.3 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Importin_rep PF18773.1 pGCA_001587035_00013 - 0.018 14.7 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF327 PF03885.13 pGCA_001587035_00013 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF327) BLOC1_2 PF10046.9 pGCA_001587035_00013 - 0.94 9.8 4.4 0.26 11.6 0.4 2.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GPD PF05954.11 pGCA_001587035_00014 - 5.9e-18 65.2 0.0 9.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pGCA_001587035_00014 - 0.11 12.2 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pGCA_001587035_00015 - 3.5e-47 161.1 0.0 3.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pGCA_001587035_00016 - 2.2e-110 370.0 0.0 2.5e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pGCA_001587035_00017 - 2.2e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pGCA_001587035_00017 - 0.021 14.7 0.3 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pGCA_001587035_00017 - 0.072 12.6 0.2 0.17 11.3 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pGCA_001587035_00018 - 6e-170 565.6 0.0 7.1e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pGCA_001587035_00018 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pGCA_001587035_00019 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pGCA_001587035_00019 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pGCA_001587035_00020 - 1.2e-12 47.9 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pGCA_001587035_00020 - 0.00013 22.0 0.2 0.00079 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pGCA_001587035_00020 - 0.0034 17.4 13.8 0.059 13.3 1.9 4.2 3 2 0 3 3 3 2 PX domain T6SS-SciN PF12790.7 pGCA_001587035_00021 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pGCA_001587035_00022 - 4.7e-112 374.8 0.0 5.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pGCA_001587035_00023 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pGCA_001587035_00024 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pGCA_001587035_00025 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pGCA_001587035_00025 - 5.9e-40 137.1 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pGCA_001587035_00025 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pGCA_001587035_00025 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pGCA_001587035_00025 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pGCA_001587035_00025 - 0.0041 16.8 4.8 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pGCA_001587035_00025 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pGCA_001587035_00026 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pGCA_001587035_00026 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pGCA_001587035_00026 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain DUF3870 PF12986.7 pGCA_001587035_00027 - 0.098 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) DUF2459 PF09601.10 pGCA_001587035_00030 - 0.053 13.3 1.1 0.12 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2459) BLOC1_2 PF10046.9 pGCA_001587035_00030 - 0.1 12.9 2.0 0.25 11.7 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Put_DNA-bind_N PF06971.13 pGCA_001587035_00031 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Toprim_3 PF13362.6 pGCA_001587035_00032 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pGCA_001587035_00032 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pGCA_001587035_00032 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pGCA_001587035_00032 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold NYN PF01936.18 pGCA_001587035_00034 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pGCA_001587035_00034 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pGCA_001587035_00034 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain PTS-HPr PF00381.19 pGCA_001587035_00035 - 0.17 12.1 0.0 0.19 12.0 0.0 1.0 1 0 0 1 1 1 0 PTS HPr component phosphorylation site RHH_7 PF16777.5 pGCA_001587035_00036 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pGCA_001587035_00036 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 pGCA_001587035_00037 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001587035_00037 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001587035_00037 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pGCA_001587035_00037 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pGCA_001587035_00038 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_001587035_00038 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pGCA_001587035_00039 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_001587035_00039 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_001587035_00039 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_001587035_00039 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_001587035_00039 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pGCA_001587035_00040 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_001587035_00040 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_001587035_00040 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_001587035_00040 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_001587035_00040 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_001587035_00040 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_001587035_00040 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pGCA_001587035_00041 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 pGCA_001587035_00042 - 0.047 13.8 0.3 4.4 7.5 0.0 2.3 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pGCA_001587035_00043 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_001587035_00043 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Asp-B-Hydro_N PF05279.11 pGCA_001587035_00045 - 2.9 7.9 12.2 3.4 7.7 12.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GTP_EFTU PF00009.27 pGCA_001587035_00046 - 8.1e-59 198.4 0.4 1.1e-58 198.0 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_001587035_00046 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_001587035_00046 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_001587035_00046 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_001587035_00046 - 1.8e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_001587035_00046 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_001587035_00046 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_001587035_00046 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_001587035_00046 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pGCA_001587035_00048 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_001587035_00048 - 0.022 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pGCA_001587035_00049 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_001587035_00049 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_001587035_00049 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_001587035_00049 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_001587035_00049 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_001587035_00049 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_001587035_00049 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_001587035_00049 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_001587035_00049 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_001587035_00049 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_001587035_00049 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_001587035_00049 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_001587035_00049 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_001587035_00049 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_001587035_00049 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_001587035_00049 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_001587035_00049 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pGCA_001587035_00050 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pGCA_001587035_00051 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_001587035_00051 - 0.077 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_001587035_00051 - 0.74 9.8 5.2 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pGCA_001587035_00052 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pGCA_001587035_00053 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_001587035_00053 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_001587035_00053 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_001587035_00053 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pGCA_001587035_00054 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_001587035_00054 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_001587035_00054 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_001587035_00054 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Phage_pRha PF09669.10 pGCA_001587035_00055 - 3.4e-21 75.6 0.1 3.4e-21 75.6 0.1 2.0 2 1 0 2 2 2 1 Phage regulatory protein Rha (Phage_pRha) T2SSE PF00437.20 pGCA_001587035_00056 - 6.4e-54 182.8 0.0 7.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_001587035_00056 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_001587035_00056 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_001587035_00056 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_001587035_00056 - 0.0014 18.9 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_001587035_00056 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_001587035_00056 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_001587035_00056 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_001587035_00056 - 0.0049 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_001587035_00056 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_001587035_00056 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_001587035_00056 - 0.0088 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_001587035_00056 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_001587035_00056 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_001587035_00056 - 0.022 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_001587035_00056 - 0.023 14.8 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_001587035_00056 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_001587035_00056 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_001587035_00056 - 0.035 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_001587035_00056 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_001587035_00056 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_001587035_00056 - 0.039 13.2 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_001587035_00056 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_001587035_00056 - 0.063 11.9 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_001587035_00056 - 0.065 13.6 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_001587035_00056 - 0.085 12.8 0.4 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_001587035_00056 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_001587035_00056 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_001587035_00056 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_001587035_00056 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_001587035_00056 - 0.29 11.6 3.1 0.32 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pGCA_001587035_00057 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_001587035_00057 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pGCA_001587035_00058 - 6.2e-55 186.2 1.7 1e-54 185.5 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_001587035_00058 - 0.082 12.7 0.3 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pGCA_001587035_00059 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_001587035_00059 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pGCA_001587035_00060 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_001587035_00060 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pGCA_001587035_00061 - 2.7e-29 102.5 30.5 2.7e-29 102.5 30.5 1.5 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_001587035_00061 - 0.21 11.4 1.5 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered T4SS PF07996.11 pGCA_001587035_00062 - 1.9e-28 100.2 13.4 2.7e-28 99.7 13.4 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_001587035_00062 - 0.0072 16.4 1.8 0.021 15.0 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_001587035_00062 - 0.0092 16.7 6.0 0.0092 16.7 6.0 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pGCA_001587035_00062 - 0.072 13.8 1.0 0.072 13.8 1.0 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Phage_holin_6_1 PF09682.10 pGCA_001587035_00062 - 0.13 12.7 8.7 0.27 11.7 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF3752 PF12572.8 pGCA_001587035_00062 - 2.3 8.7 8.3 9.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) WXG100 PF06013.12 pGCA_001587035_00062 - 7.2 6.9 12.9 1 9.7 0.7 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG IF2_N PF04760.15 pGCA_001587035_00063 - 6.5e-05 22.7 5.8 0.00049 19.9 2.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HTH_16 PF12645.7 pGCA_001587035_00063 - 0.013 15.5 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_001587035_00063 - 0.029 15.1 0.5 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor FliG_N PF14842.6 pGCA_001587035_00063 - 0.039 14.5 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain SSB PF00436.25 pGCA_001587035_00064 - 2.5e-24 85.3 0.1 3.2e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family FapA PF03961.13 pGCA_001587035_00065 - 0.072 11.7 13.7 0.0066 15.1 7.2 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3251 PF11622.8 pGCA_001587035_00065 - 0.085 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Fib_alpha PF08702.10 pGCA_001587035_00065 - 1.1 9.4 11.4 0.062 13.5 3.7 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 pGCA_001587035_00065 - 1.8 8.9 13.9 1 9.7 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pGCA_001587035_00065 - 4.4 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Ax_dynein_light PF10211.9 pGCA_001587035_00065 - 4.5 7.2 15.1 0.051 13.5 3.7 2.7 3 0 0 3 3 3 0 Axonemal dynein light chain Phage_pRha PF09669.10 pGCA_001587035_00066 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) CagE_TrbE_VirB PF03135.14 pGCA_001587035_00067 - 9.3e-49 166.3 0.3 2.3e-48 165.0 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_001587035_00067 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pGCA_001587035_00067 - 1.5e-07 30.7 0.8 3.5e-07 29.5 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pGCA_001587035_00067 - 0.039 14.0 5.4 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 pGCA_001587035_00068 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_001587035_00068 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pGCA_001587035_00070 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_001587035_00070 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pGCA_001587035_00071 - 9.1e-32 110.2 0.6 1.2e-31 109.8 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_001587035_00071 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_001587035_00071 - 0.065 13.3 4.7 0.68 10.0 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_001587035_00071 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pGCA_001587035_00072 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001587035_00072 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001587035_00072 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_001587035_00072 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_001587035_00072 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_001587035_00072 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_001587035_00072 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicA_toxin PF07927.12 pGCA_001587035_00073 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pGCA_001587035_00074 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pGCA_001587035_00075 - 0.0043 17.1 1.7 0.0054 16.8 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 pGCA_001587035_00075 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 pGCA_001587035_00076 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pGCA_001587035_00076 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pGCA_001587035_00077 - 2.1e-08 34.4 0.0 4.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_001587035_00077 - 0.088 12.8 0.8 0.37 10.8 0.3 2.3 2 0 0 2 2 2 0 PAZ domain 5_3_exonuc PF01367.20 pGCA_001587035_00077 - 0.17 12.5 4.7 0.89 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pGCA_001587035_00078 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Sds3 PF08598.11 pGCA_001587035_00080 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pGCA_001587035_00080 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pGCA_001587035_00080 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pGCA_001587035_00081 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_001587035_00081 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_001587035_00081 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pGCA_001587035_00081 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pGCA_001587035_00081 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 pGCA_001587035_00082 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 pGCA_001587035_00083 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pGCA_001587035_00083 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pGCA_001587035_00083 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pGCA_001587035_00083 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pGCA_001587035_00083 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pGCA_001587035_00083 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pGCA_001587035_00083 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 pGCA_001587035_00083 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 pGCA_001587035_00083 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 pGCA_001587035_00083 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 pGCA_001587035_00083 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pGCA_001587035_00083 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 pGCA_001587035_00083 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 pGCA_001587035_00083 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain SNF2_N PF00176.23 pGCA_001587035_00084 - 1.4e-16 60.1 0.8 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_001587035_00084 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_001587035_00084 - 9.4e-07 29.2 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_001587035_00084 - 1.3e-05 25.0 2.0 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_001587035_00084 - 3e-05 24.5 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pGCA_001587035_00085 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pGCA_001587035_00086 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001587035_00086 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001587035_00086 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase NnrS PF05940.12 pGCA_001587035_00088 - 0.023 14.1 9.9 0.028 13.8 9.9 1.0 1 0 0 1 1 1 0 NnrS protein DUF2070 PF09843.9 pGCA_001587035_00088 - 0.054 11.8 13.4 0.063 11.6 13.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 pGCA_001587035_00088 - 0.15 12.4 19.9 0.53 10.7 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Glucos_trans_II PF14264.6 pGCA_001587035_00088 - 0.51 9.7 27.0 0.49 9.7 7.9 2.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF5385 PF17359.2 pGCA_001587035_00088 - 0.52 9.8 9.3 0.099 12.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NVEALA PF14055.6 pGCA_001587035_00088 - 4.1 7.4 6.4 4.2 7.4 0.2 2.9 1 1 2 3 3 3 0 NVEALA protein TssN PF17555.2 pGCA_001587035_00088 - 4.7 6.5 20.7 5.9 6.2 20.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2663 PF10864.8 pGCA_001587035_00088 - 6.7 7.1 10.9 36 4.8 8.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Lipase_3 PF01764.25 pGCA_001587035_00089 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pGCA_001587035_00089 - 2.8e-07 30.3 0.0 6.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 pGCA_001587035_00089 - 2.7e-05 24.0 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 pGCA_001587035_00089 - 5.3e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 pGCA_001587035_00089 - 0.00045 19.9 0.1 0.00093 18.8 0.1 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pGCA_001587035_00089 - 0.0017 19.0 0.0 0.0024 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pGCA_001587035_00089 - 0.0021 18.1 0.9 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0227) DUF4450 PF14614.6 pGCA_001587035_00089 - 0.016 14.8 0.1 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF1257 PF06868.11 pGCA_001587035_00089 - 0.24 11.7 2.3 18 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1257) SBDS PF01172.18 pGCA_001587035_00089 - 0.79 9.8 5.3 0.83 9.8 1.4 3.2 2 2 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein SseC PF04888.12 pGCA_001587035_00092 - 0.0012 18.5 0.2 0.0032 17.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family APOBEC_C PF05240.14 pGCA_001587035_00092 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ThrE PF06738.12 pGCA_001587035_00092 - 0.019 14.3 0.8 0.051 12.9 0.8 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pGCA_001587035_00092 - 0.033 14.1 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone PTS_EIIC_2 PF13303.6 pGCA_001587035_00092 - 0.037 13.1 1.0 0.064 12.3 1.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC TPR_11 PF13414.6 pGCA_001587035_00092 - 0.064 12.9 0.3 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 TPR repeat Glyco_tranf_2_5 PF13712.6 pGCA_001587035_00094 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family TraG_N PF07916.11 pGCA_001587035_00095 - 3.3e-42 144.9 22.9 3.3e-42 144.9 22.9 2.2 2 1 0 2 2 2 1 TraG-like protein, N-terminal region CHMI PF02962.15 pGCA_001587035_00095 - 0.017 15.5 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase YafQ_toxin PF15738.5 pGCA_001587035_00098 - 2.5e-24 85.4 5.0 2.8e-24 85.2 5.0 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pGCA_001587035_00098 - 9.5e-06 26.1 0.3 1.2e-05 25.8 0.3 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 pGCA_001587035_00098 - 0.00012 22.0 2.5 0.00015 21.7 2.5 1.2 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system BTHB PF18410.1 pGCA_001587035_00098 - 0.086 12.7 1.5 0.87 9.4 0.1 2.4 1 1 2 3 3 3 0 Basic tilted helix bundle domain HicB_lk_antitox PF15919.5 pGCA_001587035_00100 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pGCA_001587035_00100 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicA_toxin PF07927.12 pGCA_001587035_00101 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Fic PF02661.18 pGCA_001587035_00102 - 4.4e-05 24.3 0.0 8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family Como_LCP PF02247.16 pGCA_001587035_00102 - 0.056 12.0 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Large coat protein DHHA1 PF02272.19 pGCA_001587035_00103 - 0.18 12.2 1.6 0.37 11.2 1.6 1.5 1 0 0 1 1 1 0 DHHA1 domain DUF3825 PF12873.7 pGCA_001587035_00104 - 2.2e-28 99.3 0.4 3.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF447 PF04289.12 pGCA_001587035_00105 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pGCA_001587035_00105 - 0.04 13.9 0.3 0.063 13.2 0.3 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pGCA_001587035_00105 - 0.045 13.9 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IMS_C PF11799.8 pGCA_001587035_00107 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Patched PF02460.18 pGCA_001587035_00107 - 0.024 12.8 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Patched family IMS PF00817.20 pGCA_001587035_00109 - 1.5e-25 89.9 0.2 4e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 impB/mucB/samB family CooC_C PF15976.5 pGCA_001587035_00110 - 0.015 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal PemK_toxin PF02452.17 pGCA_001587035_00110 - 0.04 14.3 0.0 0.048 14.1 0.0 1.2 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_3 PF01381.22 pGCA_001587035_00111 - 3.7e-07 30.1 0.0 4.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pGCA_001587035_00111 - 0.00017 21.9 0.0 0.00019 21.8 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pGCA_001587035_00111 - 0.00074 19.0 0.2 0.00093 18.7 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pGCA_001587035_00111 - 0.0012 18.7 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 pGCA_001587035_00111 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 pGCA_001587035_00111 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pGCA_001587035_00111 - 0.0038 17.3 0.3 0.0054 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pGCA_001587035_00111 - 0.0048 17.2 0.0 0.0052 17.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pGCA_001587035_00111 - 0.0094 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pGCA_001587035_00111 - 0.0099 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pGCA_001587035_00111 - 0.013 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pGCA_001587035_00111 - 0.02 14.8 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pGCA_001587035_00111 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 pGCA_001587035_00111 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_AsnC-type PF13404.6 pGCA_001587035_00111 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 pGCA_001587035_00111 - 0.031 14.5 0.0 3 8.1 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 pGCA_001587035_00111 - 0.035 13.6 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 pGCA_001587035_00111 - 0.08 12.7 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pGCA_001587035_00111 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pGCA_001587035_00111 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5601 PF18151.1 pGCA_001587035_00113 - 0.0084 16.4 0.4 0.016 15.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) IFP_35_N PF07334.13 pGCA_001587035_00113 - 0.14 12.2 4.9 2 8.5 0.4 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HSBP1 PF06825.12 pGCA_001587035_00115 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CCDC-167 PF15188.6 pGCA_001587035_00115 - 0.026 14.9 0.3 0.039 14.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 pGCA_001587035_00115 - 0.11 11.8 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4164 PF13747.6 pGCA_001587035_00115 - 0.11 12.8 0.3 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Phage_NinH PF06322.11 pGCA_001587035_00116 - 0.1 12.5 0.2 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 Phage NinH protein WGR PF05406.15 pGCA_001587035_00120 - 4.2e-07 29.9 0.3 4.9e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pGCA_001587035_00120 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like FlaC_arch PF05377.11 pGCA_001587035_00121 - 0.0068 16.8 1.5 0.0068 16.8 1.5 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phage_integrase PF00589.22 pGCA_001587035_00122 - 4.9e-24 85.0 0.5 8.3e-24 84.3 0.5 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pGCA_001587035_00122 - 1.2e-05 25.5 4.2 3.9e-05 23.9 1.8 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pGCA_001587035_00122 - 0.00017 21.8 4.6 0.00017 21.8 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pGCA_001587035_00122 - 0.0026 18.2 8.9 0.0086 16.5 5.3 2.9 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phyto-Amp PF15438.6 pGCA_001587035_00122 - 0.0092 15.8 0.3 0.017 15.0 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma Phage_int_SAM_3 PF14659.6 pGCA_001587035_00122 - 0.027 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain YbjN PF10722.9 pGCA_001587035_00122 - 0.029 14.4 0.3 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator IMS PF00817.20 pGCA_001717605_00001 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family DUF4368 PF14287.6 pGCA_001717605_00002 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 pGCA_001717605_00002 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.4 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 pGCA_001717605_00002 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 pGCA_001717605_00002 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 pGCA_001717605_00002 - 0.14 12.2 0.7 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Snapin_Pallidin PF14712.6 pGCA_001717605_00002 - 1.2 9.6 6.0 13 6.3 0.2 2.9 3 0 0 3 3 3 0 Snapin/Pallidin AAA_18 PF13238.6 pGCA_001717605_00003 - 1.4e-14 54.8 0.0 1.8e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pGCA_001717605_00003 - 2.8e-11 43.8 0.0 3.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pGCA_001717605_00003 - 1.9e-10 40.9 0.0 3.6e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 pGCA_001717605_00003 - 1.5e-07 30.9 0.1 3.2e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 pGCA_001717605_00003 - 4e-06 27.2 0.2 1.1e-05 25.7 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 pGCA_001717605_00003 - 7.9e-06 26.3 0.0 5.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 pGCA_001717605_00003 - 9.5e-06 26.1 0.0 4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pGCA_001717605_00003 - 1.5e-05 25.3 0.0 5.9e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pGCA_001717605_00003 - 6.5e-05 23.0 0.0 9.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pGCA_001717605_00003 - 0.00031 21.2 0.0 0.00041 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pGCA_001717605_00003 - 0.001 18.4 0.2 0.0012 18.2 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 pGCA_001717605_00003 - 0.0016 17.9 0.1 0.0038 16.7 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_19 PF13245.6 pGCA_001717605_00003 - 0.0017 18.7 0.2 0.0035 17.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 pGCA_001717605_00003 - 0.0019 17.9 0.4 0.004 16.9 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 pGCA_001717605_00003 - 0.0023 17.7 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pGCA_001717605_00003 - 0.0025 18.3 0.1 0.003 18.1 0.1 1.5 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 pGCA_001717605_00003 - 0.0033 17.4 0.4 1 9.2 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea APS_kinase PF01583.20 pGCA_001717605_00003 - 0.0047 16.8 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase TIP49 PF06068.13 pGCA_001717605_00003 - 0.0054 16.0 0.4 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 pGCA_001717605_00003 - 0.0068 15.8 1.2 0.016 14.6 0.1 2.0 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 pGCA_001717605_00003 - 0.01 15.2 1.0 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 pGCA_001717605_00003 - 0.011 14.9 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 pGCA_001717605_00003 - 0.016 14.9 0.1 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 pGCA_001717605_00003 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 pGCA_001717605_00003 - 0.018 15.0 0.6 0.036 14.0 0.2 1.7 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 pGCA_001717605_00003 - 0.018 14.8 0.1 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 pGCA_001717605_00003 - 0.02 14.5 0.3 0.071 12.7 0.1 2.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 pGCA_001717605_00003 - 0.024 14.8 0.2 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.15 pGCA_001717605_00003 - 0.033 14.1 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 pGCA_001717605_00003 - 0.038 13.2 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ArsA_ATPase PF02374.15 pGCA_001717605_00003 - 0.04 13.1 0.1 0.099 11.8 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase MKT1_N PF12247.8 pGCA_001717605_00003 - 0.042 14.2 0.0 0.097 13.0 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Hydin_ADK PF17213.3 pGCA_001717605_00003 - 0.043 14.1 1.2 0.054 13.8 0.2 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 pGCA_001717605_00003 - 0.048 13.6 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 pGCA_001717605_00003 - 0.051 13.4 1.5 0.1 12.4 1.5 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 pGCA_001717605_00003 - 0.051 14.0 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 pGCA_001717605_00003 - 0.055 13.2 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GvpD PF07088.11 pGCA_001717605_00003 - 0.057 12.0 0.4 0.41 9.2 0.1 2.1 2 1 0 2 2 2 0 GvpD gas vesicle protein AAA_7 PF12775.7 pGCA_001717605_00003 - 0.059 12.9 0.2 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 pGCA_001717605_00003 - 0.079 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 pGCA_001717605_00003 - 0.08 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 pGCA_001717605_00003 - 0.086 12.5 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase1 PF18748.1 pGCA_001717605_00003 - 0.1 12.1 0.1 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 IPT PF01745.16 pGCA_001717605_00003 - 0.11 11.9 0.2 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 Isopentenyl transferase Ploopntkinase3 PF18751.1 pGCA_001717605_00003 - 0.12 12.2 0.4 0.4 10.6 0.0 2.0 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 APH PF01636.23 pGCA_001717605_00004 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_001717605_00004 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pGCA_001717605_00004 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pGCA_001717605_00004 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pGCA_001717605_00004 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pGCA_001717605_00004 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pGCA_001717605_00005 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pGCA_001717605_00006 - 6.8e-11 42.6 0.0 8.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_001717605_00006 - 0.014 14.6 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase CPT PF07931.12 pGCA_001717605_00007 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 pGCA_001717605_00007 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pGCA_001717605_00007 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pGCA_001717605_00007 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 pGCA_001717605_00007 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3847 PF12958.7 pGCA_001717605_00008 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 pGCA_001717605_00008 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 pGCA_001717605_00008 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 pGCA_001717605_00008 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MobA_MobL PF03389.15 pGCA_001717605_00009 - 3.7e-79 265.5 0.0 1.4e-78 263.6 0.0 1.9 2 0 0 2 2 2 1 MobA/MobL family Spectrin PF00435.21 pGCA_001717605_00009 - 0.015 15.8 2.4 0.18 12.3 0.2 2.9 2 1 0 2 2 2 0 Spectrin repeat Prominin PF05478.11 pGCA_001717605_00009 - 0.02 12.9 1.9 0.029 12.4 1.9 1.2 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.6 pGCA_001717605_00009 - 0.021 15.2 2.0 0.059 13.8 0.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF2408 PF10303.9 pGCA_001717605_00009 - 0.032 14.8 2.4 0.06 13.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Tup_N PF08581.10 pGCA_001717605_00009 - 0.065 13.5 2.3 6.6 7.1 0.3 3.5 4 0 0 4 4 4 0 Tup N-terminal Mod_r PF07200.13 pGCA_001717605_00009 - 0.65 10.1 8.1 0.62 10.2 0.4 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SOAR PF16533.5 pGCA_001717605_00009 - 1.2 9.1 5.4 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region DUF4407 PF14362.6 pGCA_001717605_00009 - 5.1 6.4 8.4 53 3.0 8.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_25 PF13481.6 pGCA_001717605_00010 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 pGCA_001717605_00010 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 pGCA_001717605_00010 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 pGCA_001717605_00010 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 pGCA_001717605_00010 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 pGCA_001717605_00010 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 pGCA_001717605_00010 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 pGCA_001717605_00010 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 pGCA_001717605_00010 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 pGCA_001717605_00010 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 pGCA_001717605_00010 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 pGCA_001717605_00010 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 pGCA_001717605_00010 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 pGCA_001717605_00010 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 pGCA_001717605_00010 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 pGCA_001717605_00010 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 pGCA_001717605_00010 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IMS_C PF11799.8 pGCA_001717605_00011 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 pGCA_001717605_00011 - 0.0002 21.5 0.0 0.00067 19.8 0.1 1.9 2 0 0 2 2 2 1 IMS family HHH motif Cob_adeno_trans PF01923.18 pGCA_001717605_00014 - 0.014 15.6 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3825 PF12873.7 pGCA_001717605_00015 - 4.2e-29 101.7 0.3 6.7e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) DUF4795 PF16043.5 pGCA_001717605_00016 - 0.026 14.1 0.1 0.043 13.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SGT1 PF07093.11 pGCA_001717605_00017 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 pGCA_001717605_00017 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 pGCA_001717605_00017 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5309 PF17236.2 pGCA_001717605_00018 - 3e-05 23.5 0.5 3.3e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5309) HicA_toxin PF07927.12 pGCA_001717605_00019 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pGCA_001717605_00020 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pGCA_001717605_00020 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ParE_toxin PF05016.15 pGCA_001717605_00022 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 pGCA_001717605_00024 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF4131 PF13567.6 pGCA_001717605_00025 - 0.00082 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 pGCA_001717605_00025 - 0.014 15.3 3.1 0.018 15.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 pGCA_001717605_00025 - 0.055 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2721 PF11026.8 pGCA_001717605_00025 - 0.068 13.1 3.9 0.085 12.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF2663 PF10864.8 pGCA_001717605_00025 - 0.13 12.7 1.9 0.16 12.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) TraG_N PF07916.11 pGCA_001717605_00026 - 3e-39 135.2 20.8 3e-39 135.2 20.8 3.2 3 1 0 4 4 4 1 TraG-like protein, N-terminal region Glyco_tranf_2_5 PF13712.6 pGCA_001717605_00027 - 0.0018 18.0 4.5 0.0035 17.1 4.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family UvrA_DNA-bind PF17755.1 pGCA_001717605_00028 - 0.0008 19.7 0.3 0.33 11.3 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 pGCA_001717605_00029 - 0.003 17.9 0.2 2.1 8.7 0.1 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain Ank_2 PF12796.7 pGCA_001717605_00032 - 1.4e-11 44.8 0.4 1.1e-06 29.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pGCA_001717605_00032 - 5.4e-10 38.6 0.4 0.0094 16.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 pGCA_001717605_00032 - 0.0016 19.0 0.1 0.32 11.6 0.0 3.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 pGCA_001717605_00032 - 0.0035 17.7 0.0 17 6.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 pGCA_001717605_00032 - 0.016 15.5 0.1 1.6 9.1 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pGCA_001717605_00033 - 1.6e-07 31.5 0.0 1.6e-07 31.5 0.0 3.3 2 1 0 2 2 2 1 Restriction endonuclease fold toxin 7 Ank_2 PF12796.7 pGCA_001717605_00034 - 1.6e-14 54.2 0.1 1.5e-08 35.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pGCA_001717605_00034 - 6.1e-10 38.5 0.0 0.00093 19.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 pGCA_001717605_00034 - 8.6e-06 26.2 0.0 0.0017 18.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 pGCA_001717605_00034 - 3.4e-05 24.1 0.0 2.5 8.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pGCA_001717605_00034 - 0.0018 18.6 0.3 0.13 12.6 0.0 3.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) APG17 PF04108.12 pGCA_001717605_00034 - 0.017 14.2 0.7 0.024 13.8 0.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF2345 PF10106.9 pGCA_001717605_00035 - 0.0046 16.8 2.2 0.016 15.1 2.2 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) DUF3540 PF12059.8 pGCA_001717605_00035 - 0.029 14.2 0.9 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) Gp5_C PF06715.12 pGCA_001717605_00035 - 0.094 12.9 0.1 0.094 12.9 0.1 4.7 3 1 2 5 5 5 0 Gp5 C-terminal repeat (3 copies) Bacteriocin_IIc PF10439.9 pGCA_001717605_00036 - 0.0019 18.2 10.8 0.0019 18.2 10.8 1.8 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 pGCA_001717605_00036 - 0.04 13.9 10.0 0.084 12.9 10.0 1.4 1 0 0 1 1 1 0 Glycine zipper DUF3482 PF11981.8 pGCA_001717605_00036 - 0.1 12.0 1.3 0.21 11.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_YMGG PF13441.6 pGCA_001717605_00036 - 0.17 11.6 8.3 0.36 10.6 8.3 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 pGCA_001717605_00036 - 1.4 8.9 12.1 2.7 7.9 12.1 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1269 PF06897.12 pGCA_001717605_00036 - 5.8 7.3 7.3 13 6.1 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Phage_GPD PF05954.11 pGCA_001717605_00038 - 5.4e-18 65.3 0.0 8.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pGCA_001717605_00038 - 0.11 12.1 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family T6SS_TssG PF06996.11 pGCA_001717605_00039 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG T6SS_TssF PF05947.12 pGCA_001717605_00040 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF GPW_gp25 PF04965.14 pGCA_001717605_00041 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pGCA_001717605_00041 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pGCA_001717605_00041 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) VipB PF05943.12 pGCA_001717605_00042 - 1e-169 564.9 0.0 1.2e-169 564.6 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pGCA_001717605_00042 - 0.096 12.7 0.8 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide T6SS_VipA PF05591.12 pGCA_001717605_00043 - 1.2e-51 174.6 3.8 1.3e-51 174.4 3.8 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pGCA_001717605_00043 - 0.082 11.5 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase T6SS_VasJ PF16989.5 pGCA_001717605_00044 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pGCA_001717605_00044 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pGCA_001717605_00044 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 pGCA_001717605_00044 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS-SciN PF12790.7 pGCA_001717605_00045 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasE PF05936.12 pGCA_001717605_00046 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 pGCA_001717605_00047 - 1.1e-34 120.0 0.0 1.2e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_HCP PF05638.12 pGCA_001717605_00048 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImcF-related_N PF14331.6 pGCA_001717605_00049 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pGCA_001717605_00049 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pGCA_001717605_00049 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pGCA_001717605_00049 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pGCA_001717605_00049 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pGCA_001717605_00049 - 0.0033 17.1 5.0 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pGCA_001717605_00049 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FHA PF00498.26 pGCA_001717605_00050 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pGCA_001717605_00050 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pGCA_001717605_00050 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain Y1_Tnp PF01797.16 pGCA_001717605_00053 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pGCA_001717605_00054 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pGCA_001717605_00054 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pGCA_001717605_00054 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pGCA_001717605_00054 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pGCA_001717605_00054 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pGCA_001717605_00054 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pGCA_001717605_00054 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pGCA_001717605_00054 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pGCA_001717605_00054 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 pGCA_001717605_00055 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 pGCA_001717605_00055 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 pGCA_001717605_00056 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pGCA_001717605_00057 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pGCA_001717605_00057 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pGCA_001717605_00057 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pGCA_001717605_00057 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pGCA_001717605_00057 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pGCA_001717605_00057 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pGCA_001717605_00057 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pGCA_001717605_00057 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pGCA_001717605_00057 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Fic PF02661.18 pGCA_001717605_00058 - 8.4e-24 84.3 0.1 2.1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family S_layer_C PF05124.12 pGCA_001717605_00058 - 6.6 6.6 8.7 0.56 10.2 2.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region Y1_Tnp PF01797.16 pGCA_001717605_00059 - 8.8e-37 125.9 2.5 1.2e-36 125.4 2.5 1.2 1 0 0 1 1 1 1 Transposase IS200 like OrfB_Zn_ribbon PF07282.11 pGCA_001717605_00060 - 2.2e-22 78.7 1.3 4.6e-22 77.7 1.3 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 pGCA_001717605_00060 - 5.9e-13 49.1 2.4 1.4e-12 47.9 2.4 1.6 1 0 0 1 1 1 1 Probable transposase HTH_OrfB_IS605 PF12323.8 pGCA_001717605_00060 - 3.8e-10 39.1 2.8 8.4e-10 38.0 2.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HypA PF01155.19 pGCA_001717605_00060 - 0.022 14.8 0.4 0.053 13.5 0.4 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 4_1_CTD PF05902.13 pGCA_001717605_00060 - 0.058 13.5 0.1 0.35 11.0 0.0 2.3 3 0 0 3 3 3 0 4.1 protein C-terminal domain (CTD) Zn_ribbon_17 PF17120.5 pGCA_001717605_00060 - 0.071 12.7 0.5 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1161 PF06649.12 pGCA_001717605_00060 - 0.12 12.6 0.8 0.32 11.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Prok-RING_1 PF14446.6 pGCA_001717605_00060 - 0.16 11.9 3.2 0.36 10.8 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Spt4 PF06093.13 pGCA_001717605_00060 - 0.82 9.8 4.4 0.81 9.8 2.2 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3492 PF11997.8 pGCA_001717605_00061 - 0.19 11.4 2.9 0.5 10.1 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CLZ PF16526.5 pGCA_001717605_00061 - 0.99 9.8 4.8 11 6.5 0.2 3.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MeMO_Hyd_G PF02964.16 pGCA_001717605_00062 - 0.078 13.0 0.7 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain Vta1 PF04652.16 pGCA_001717605_00062 - 2.5 8.1 10.2 0.043 13.8 1.0 2.5 3 0 0 3 3 3 0 Vta1 like DUF2974 PF11187.8 pGCA_001717605_00063 - 1.4e-06 28.0 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 pGCA_001717605_00063 - 1e-05 25.4 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 pGCA_001717605_00063 - 0.0019 17.7 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pGCA_001717605_00063 - 0.0036 17.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF4450 PF14614.6 pGCA_001717605_00063 - 0.016 14.8 0.2 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4450) UPF0227 PF05728.12 pGCA_001717605_00063 - 0.028 14.4 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 pGCA_001717605_00063 - 0.028 13.0 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 pGCA_001717605_00063 - 0.049 14.2 0.0 0.069 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 pGCA_001717605_00064 - 0.00072 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pGCA_001717605_00064 - 0.044 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 pGCA_001717605_00064 - 0.1 12.4 0.2 0.28 11.1 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Put_DNA-bind_N PF06971.13 pGCA_001717605_00068 - 0.034 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus AAA_31 PF13614.6 pGCA_001717605_00070 - 0.00011 22.2 0.6 0.0014 18.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001717605_00070 - 0.0021 18.1 0.9 0.017 15.2 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001717605_00070 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pGCA_001717605_00071 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_25 PF13481.6 pGCA_001717605_00072 - 4.8e-15 55.7 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001717605_00072 - 0.0003 20.2 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001717605_00072 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pGCA_001717605_00072 - 0.0091 15.4 0.4 0.074 12.4 0.0 2.5 3 1 0 3 3 3 1 KaiC AAA PF00004.29 pGCA_001717605_00072 - 0.021 15.2 0.5 0.33 11.4 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ApoC-I PF04691.12 pGCA_001717605_00072 - 0.16 11.9 3.3 5.1 7.1 0.0 3.9 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) CbiA PF01656.23 pGCA_001717605_00072 - 0.24 11.4 2.2 1.1 9.4 2.2 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_001717605_00072 - 0.7 9.5 5.5 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain DUF1947 PF09183.10 pGCA_001717605_00072 - 0.73 10.2 6.3 1.7 9.0 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) HicA_toxin PF07927.12 pGCA_001717605_00073 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pGCA_001717605_00074 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pGCA_001717605_00076 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pGCA_001717605_00076 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pGCA_001717605_00076 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) nec1 PF10379.9 pGCA_001717605_00077 - 0.036 13.6 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 pGCA_001717605_00079 - 3.2e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pGCA_001717605_00079 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_001717605_00079 - 0.12 13.0 3.6 1.2 9.8 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Paz_1 PF18349.1 pGCA_001717605_00079 - 0.12 12.3 0.9 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 PAZ domain TSC21 PF15217.6 pGCA_001717605_00079 - 0.17 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 TSC21 family CdvA PF18822.1 pGCA_001717605_00081 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pGCA_001717605_00081 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pGCA_001717605_00081 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pGCA_001717605_00082 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_001717605_00082 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_001717605_00082 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pGCA_001717605_00082 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pGCA_001717605_00082 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain Relaxase PF03432.14 pGCA_001717605_00083 - 3.7e-10 39.8 7.6 3.7e-10 39.8 7.6 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain Peptidase_C39 PF03412.15 pGCA_001717605_00085 - 5e-18 65.2 0.0 6.6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pGCA_001717605_00085 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 pGCA_001717605_00085 - 0.053 14.1 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family GramPos_pilinBB PF16569.5 pGCA_001717605_00088 - 0.016 16.0 3.9 0.19 12.6 1.9 2.3 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain DUF2768 PF10966.8 pGCA_001717605_00088 - 0.052 14.0 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SNF2_N PF00176.23 pGCA_001717605_00089 - 2.6e-16 59.3 1.7 4.4e-16 58.5 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_001717605_00089 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_001717605_00089 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_001717605_00089 - 7.6e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_001717605_00089 - 2.2e-05 24.9 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pGCA_001717605_00090 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pGCA_001717605_00091 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001717605_00091 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001717605_00091 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_001717605_00091 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_001717605_00091 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pGCA_001717605_00092 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_001717605_00092 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pGCA_001717605_00093 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_001717605_00093 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_001717605_00093 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_001717605_00093 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_001717605_00093 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pGCA_001717605_00094 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_001717605_00094 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_001717605_00094 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_001717605_00094 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_001717605_00094 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_001717605_00094 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_001717605_00094 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pGCA_001717605_00095 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 pGCA_001717605_00096 - 0.047 13.8 0.3 4.4 7.5 0.0 2.3 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pGCA_001717605_00097 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_001717605_00097 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain GTP_EFTU PF00009.27 pGCA_001717605_00100 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_001717605_00100 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_001717605_00100 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_001717605_00100 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_001717605_00100 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_001717605_00100 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_001717605_00100 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_001717605_00100 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_001717605_00100 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pGCA_001717605_00102 - 1.2e-05 25.3 2.3 3.2e-05 23.8 2.3 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_001717605_00102 - 0.03 14.3 4.7 0.03 14.3 1.1 2.5 1 1 0 2 2 2 0 Intein splicing domain Topoisom_bac PF01131.20 pGCA_001717605_00104 - 9e-97 324.7 8.0 1.3e-96 324.2 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_001717605_00104 - 9.7e-12 45.0 0.1 9.7e-12 45.0 0.1 2.8 3 1 0 3 3 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_001717605_00104 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_001717605_00104 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_001717605_00104 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_001717605_00104 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_001717605_00104 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain EF-hand_8 PF13833.6 pGCA_001717605_00104 - 0.052 13.4 0.2 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_4 PF13894.6 pGCA_001717605_00104 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_001717605_00104 - 0.086 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pGCA_001717605_00104 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_001717605_00104 - 0.38 11.0 3.0 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_001717605_00104 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_001717605_00104 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_001717605_00104 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_001717605_00104 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_001717605_00104 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1461 PF07314.11 pGCA_001717605_00105 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CdhD PF03599.16 pGCA_001717605_00106 - 0.004 15.9 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 pGCA_001717605_00106 - 0.056 13.2 0.7 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pGCA_001717605_00107 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pGCA_001717605_00107 - 1.3 8.8 9.6 3.3 7.4 8.5 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT20 PF14931.6 pGCA_001717605_00107 - 4.9 7.3 10.2 1.5 9.0 0.5 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 TrbM PF07424.11 pGCA_001717605_00108 - 3.9e-38 130.8 2.1 5e-38 130.5 2.1 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 pGCA_001717605_00108 - 0.17 10.9 0.1 1 8.4 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Cag12 PF13117.6 pGCA_001717605_00109 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pGCA_001717605_00109 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) T4SS-DNA_transf PF02534.14 pGCA_001717605_00110 - 6.8e-104 348.3 0.1 9.2e-104 347.8 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_001717605_00110 - 3.1e-24 85.3 0.0 6.1e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_001717605_00110 - 2.6e-15 56.3 0.0 5.1e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 pGCA_001717605_00111 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_001717605_00111 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_001717605_00111 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_001717605_00111 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_001717605_00111 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_001717605_00111 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pGCA_001717605_00111 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pGCA_001717605_00111 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_001717605_00111 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_001717605_00111 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_001717605_00111 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_001717605_00111 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pGCA_001717605_00111 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 pGCA_001717605_00111 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 pGCA_001717605_00111 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 pGCA_001717605_00111 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 pGCA_001717605_00111 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 pGCA_001717605_00111 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pGCA_001717605_00111 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 pGCA_001717605_00111 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pGCA_001717605_00111 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pGCA_001717605_00111 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_001717605_00111 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_001717605_00111 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_001717605_00111 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pGCA_001717605_00111 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pGCA_001717605_00111 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pGCA_001717605_00111 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_001717605_00111 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_001717605_00111 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_001717605_00111 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pGCA_001717605_00112 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_001717605_00112 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pGCA_001717605_00113 - 4.5e-56 189.9 2.1 7.1e-56 189.3 2.1 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pGCA_001717605_00113 - 0.021 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 TraE protein VirB8 PF04335.13 pGCA_001717605_00114 - 1.6e-52 178.4 0.4 1.8e-52 178.3 0.4 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_001717605_00114 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pGCA_001717605_00115 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pGCA_001717605_00115 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pGCA_001717605_00115 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pGCA_001717605_00116 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_001717605_00116 - 0.065 13.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pGCA_001717605_00116 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) T4SS PF07996.11 pGCA_001717605_00117 - 1.8e-28 100.3 13.3 2.5e-28 99.9 13.3 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_001717605_00117 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pGCA_001717605_00117 - 0.017 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pGCA_001717605_00117 - 0.5 11.1 11.4 0.41 11.3 4.5 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 pGCA_001717605_00118 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_001717605_00118 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_001717605_00118 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_001717605_00118 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pGCA_001717605_00119 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 pGCA_001717605_00120 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 pGCA_001717605_00121 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pGCA_001717605_00121 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pGCA_001717605_00121 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 pGCA_001717605_00122 - 6.9e-51 173.3 0.4 1.6e-50 172.1 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_001717605_00122 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 pGCA_001717605_00123 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_001717605_00123 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pGCA_001717605_00125 - 0.00056 20.0 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 CRISPR associated protein Cas2 Resolvase PF00239.21 pGCA_001717605_00126 - 1.4e-33 116.0 0.8 2e-33 115.6 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_Mga PF08280.11 pGCA_001717605_00126 - 0.03 14.4 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_38 PF13936.6 pGCA_001717605_00126 - 0.042 13.6 0.8 4.9 7.0 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain RepL PF05732.11 pGCA_001717605_00127 - 5.2e-17 61.8 0.0 6e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_5 PF01022.20 pGCA_001717605_00127 - 6.3e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 pGCA_001717605_00127 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF4423 PF14394.6 pGCA_001717605_00127 - 0.00096 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) HTH_11 PF08279.12 pGCA_001717605_00127 - 0.0036 17.2 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 pGCA_001717605_00127 - 0.0037 17.2 0.0 0.0054 16.6 0.0 1.2 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 pGCA_001717605_00127 - 0.0046 16.8 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 pGCA_001717605_00127 - 0.0048 16.9 0.0 0.0068 16.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 pGCA_001717605_00127 - 0.023 15.0 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 pGCA_001717605_00127 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_rep_org_N PF09681.10 pGCA_001717605_00127 - 0.038 13.9 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) CRISPR_Cas2 PF09827.9 pGCA_001717605_00128 - 1.6e-11 44.2 0.1 2e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas2 Citrate_ly_lig PF08218.11 pGCA_001717605_00128 - 0.093 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain TIR_2 PF13676.6 pGCA_001717605_00129 - 2.1e-05 25.1 0.1 8.4e-05 23.2 0.1 2.1 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 pGCA_001717605_00129 - 0.012 16.0 1.2 0.012 16.0 1.2 3.1 3 1 0 3 3 3 0 MTH538 TIR-like domain (DUF1863) T_Ag_DNA_bind PF02217.16 pGCA_001717605_00129 - 2.7 8.6 7.4 0.19 12.3 1.8 2.0 2 1 0 2 2 2 0 Origin of replication binding protein DUF1899 PF08953.11 pGCA_001717605_00130 - 0.095 12.6 0.1 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) XhlA PF10779.9 pGCA_001717605_00130 - 0.12 12.6 1.7 0.25 11.6 1.7 1.6 1 0 0 1 1 1 0 Haemolysin XhlA AAA_25 PF13481.6 pGCA_001717605_00131 - 5.2e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001717605_00131 - 0.00056 19.3 0.0 0.0044 16.4 0.0 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001717605_00131 - 0.0015 18.3 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pGCA_001717605_00131 - 0.0044 16.8 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pGCA_001717605_00131 - 0.0061 15.9 0.1 0.046 13.1 0.0 2.6 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pGCA_001717605_00131 - 0.092 13.2 0.2 1.4 9.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pGCA_001717605_00131 - 0.2 11.7 1.5 0.69 10.0 1.4 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HicA_toxin PF07927.12 pGCA_001717605_00132 - 6.1e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pGCA_001717605_00133 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system TRADD_N PF09034.10 pGCA_001717605_00134 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain Peptidase_M4_C PF02868.15 pGCA_001717605_00134 - 0.18 11.7 1.3 0.37 10.6 0.1 2.0 2 1 1 3 3 3 0 Thermolysin metallopeptidase, alpha-helical domain AAA_31 PF13614.6 pGCA_001717605_00135 - 6.3e-05 23.0 0.6 0.0013 18.7 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001717605_00135 - 0.0021 18.1 0.8 0.017 15.2 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001717605_00135 - 0.02 14.4 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase RHH_7 PF16777.5 pGCA_001717605_00136 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG NYN PF01936.18 pGCA_001717605_00139 - 1.1e-09 39.0 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pGCA_001717605_00139 - 0.004 17.0 0.6 0.0079 16.1 0.6 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pGCA_001717605_00139 - 0.029 15.0 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain DUF2400 PF09674.10 pGCA_001717605_00140 - 0.26 11.2 4.0 0.56 10.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pGCA_001717605_00141 - 3.2e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pGCA_001717605_00141 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_001717605_00141 - 0.12 13.0 3.6 1.2 9.8 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Paz_1 PF18349.1 pGCA_001717605_00141 - 0.12 12.3 0.9 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 PAZ domain TSC21 PF15217.6 pGCA_001717605_00141 - 0.17 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 TSC21 family CitMHS PF03600.16 pGCA_001717605_00147 - 0.014 14.6 0.6 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 pGCA_001717605_00147 - 0.27 10.9 6.3 0.4 10.4 6.3 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 pGCA_001717605_00147 - 0.46 9.9 7.7 0.75 9.2 7.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DUF3810 PF12725.7 pGCA_001717605_00147 - 0.68 9.2 12.4 0.82 8.9 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DHHC PF01529.20 pGCA_001717605_00147 - 8.2 6.5 12.2 15 5.7 12.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase CitMHS PF03600.16 pGCA_001717605_00149 - 0.014 14.6 0.6 0.016 14.4 0.6 1.1 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 pGCA_001717605_00149 - 0.27 10.9 6.3 0.4 10.4 6.3 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 pGCA_001717605_00149 - 0.46 9.9 7.7 0.75 9.2 7.7 1.5 1 1 0 1 1 1 0 Spo7-like protein DUF3810 PF12725.7 pGCA_001717605_00149 - 0.68 9.2 12.4 0.82 8.9 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DHHC PF01529.20 pGCA_001717605_00149 - 8.2 6.5 12.2 15 5.7 12.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3344 PF11824.8 pGCA_001717605_00151 - 0.087 12.4 0.5 0.13 11.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) DUF5013 PF16405.5 pGCA_001717605_00153 - 0.0095 16.2 0.0 0.08 13.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5013) AMPK1_CBM PF16561.5 pGCA_001717605_00153 - 0.088 13.0 0.0 0.41 10.9 0.0 2.1 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Ribophorin_II PF05817.14 pGCA_001717605_00154 - 1.4 7.4 7.7 2 6.9 7.7 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II SseC PF04888.12 pGCA_001717605_00157 - 0.004 16.8 0.2 0.014 15.1 0.2 1.9 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 pGCA_001717605_00157 - 0.014 14.8 0.8 0.036 13.4 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter Hormone_2 PF00123.20 pGCA_001717605_00157 - 0.036 14.0 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Peptide hormone APOBEC_C PF05240.14 pGCA_001717605_00157 - 0.062 13.3 0.4 0.31 11.0 0.4 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Ank_3 PF13606.6 pGCA_001717605_00159 - 3.6e-09 36.1 0.2 0.013 16.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 pGCA_001717605_00159 - 4.6e-08 33.5 0.0 3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 pGCA_001717605_00159 - 0.00033 21.0 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pGCA_001717605_00159 - 0.0019 18.5 0.3 0.03 14.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 pGCA_001717605_00159 - 0.0027 18.3 0.1 0.17 12.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pGCA_001717605_00160 - 1.6e-07 31.5 0.0 1.6e-07 31.5 0.0 3.3 2 1 0 2 2 2 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 pGCA_001717605_00160 - 8.1 6.2 10.9 1.6 8.5 0.6 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF4637 PF15470.6 pGCA_001717605_00160 - 9.9 5.9 8.5 0.49 10.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Ank_3 PF13606.6 pGCA_001717605_00161 - 3.6e-09 36.1 0.2 0.013 16.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 pGCA_001717605_00161 - 4.6e-08 33.5 0.0 3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 pGCA_001717605_00161 - 0.00033 21.0 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pGCA_001717605_00161 - 0.0019 18.5 0.3 0.03 14.6 0.0 3.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 pGCA_001717605_00161 - 0.0027 18.3 0.1 0.17 12.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ntox24 PF15529.6 pGCA_001717605_00164 - 0.0021 18.3 0.8 0.0039 17.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial toxin 24 CobN-Mg_chel PF02514.16 pGCA_001717605_00165 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase LPD7 PF18821.1 pGCA_001717605_00166 - 0.0092 16.1 0.4 3 8.0 0.1 2.3 1 1 1 2 2 2 2 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 pGCA_001717605_00166 - 0.13 12.8 10.6 0.13 12.8 3.6 3.1 1 1 2 3 3 3 0 Immunity protein 59 ABC2_membrane_3 PF12698.7 pGCA_001717605_00166 - 0.29 10.2 0.8 0.32 10.1 0.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AHH PF14412.6 pGCA_001717605_00167 - 6.2e-16 58.5 1.7 1.2e-15 57.6 1.7 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF4299 PF14132.6 pGCA_001717605_00169 - 3.2e-08 33.4 0.1 3.7e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) A2M PF00207.22 pGCA_001717605_00169 - 0.11 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family XPG_I PF00867.18 pGCA_001717605_00169 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region Phage_GPD PF05954.11 pGCA_001717605_00171 - 5.5e-18 65.3 0.0 8.6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pGCA_001717605_00171 - 0.11 12.1 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family DivIC PF04977.15 pGCA_001717605_00173 - 0.0014 18.3 0.2 0.0014 18.3 0.2 4.2 5 0 0 5 5 5 1 Septum formation initiator DZR PF12773.7 pGCA_001717605_00174 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 pGCA_001717605_00174 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 pGCA_001717605_00174 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rapsyn_N PF10579.9 pGCA_001717605_00175 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SprT-like PF10263.9 pGCA_001717605_00177 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 pGCA_001717605_00177 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain Phage_integrase PF00589.22 pGCA_001717605_00180 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pGCA_001717605_00180 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pGCA_001717605_00180 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 pGCA_001717605_00180 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 pGCA_001717605_00180 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 pGCA_001717605_00180 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlaC_arch PF05377.11 pGCA_001717605_00181 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) WGR PF05406.15 pGCA_001717605_00182 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pGCA_001717605_00182 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like YafQ_toxin PF15738.5 pGCA_001717605_00186 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pGCA_001717605_00186 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 pGCA_001717605_00186 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 pGCA_001717605_00186 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system CCDC-167 PF15188.6 pGCA_001717605_00191 - 0.002 18.4 0.4 0.0033 17.7 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 pGCA_001717605_00191 - 0.015 15.4 3.5 0.04 14.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) HSBP1 PF06825.12 pGCA_001717605_00191 - 0.033 14.0 0.1 2.2 8.2 0.0 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Streptin-Immun PF11083.8 pGCA_001717605_00191 - 0.052 14.0 0.6 0.2 12.1 0.1 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4164 PF13747.6 pGCA_001717605_00191 - 0.1 12.9 0.4 0.32 11.3 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Trimer_CC PF08954.11 pGCA_001717605_00191 - 0.14 11.7 0.1 9.8 5.8 0.0 3.0 1 1 1 2 2 2 0 Trimerisation motif Sigma_reg_N PF13800.6 pGCA_001717605_00192 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5601 PF18151.1 pGCA_001717605_00193 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 pGCA_001717605_00193 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) HTH_3 PF01381.22 pGCA_001717605_00195 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pGCA_001717605_00195 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pGCA_001717605_00195 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 pGCA_001717605_00195 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pGCA_001717605_00195 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pGCA_001717605_00195 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pGCA_001717605_00195 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pGCA_001717605_00195 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pGCA_001717605_00195 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pGCA_001717605_00195 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pGCA_001717605_00195 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pGCA_001717605_00195 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pGCA_001717605_00195 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 pGCA_001717605_00195 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 pGCA_001717605_00195 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 pGCA_001717605_00195 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 pGCA_001717605_00195 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 pGCA_001717605_00195 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pGCA_001717605_00195 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pGCA_001717605_00195 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MobC PF05713.11 pGCA_001717605_00197 - 5.6e-09 36.3 0.3 8.1e-09 35.8 0.3 1.2 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) Vac_Fusion PF02346.16 pGCA_001717605_00197 - 0.00052 19.6 0.8 0.014 15.0 0.5 2.2 1 1 1 2 2 2 2 Chordopoxvirus multifunctional envelope protein A27 YvrJ PF12841.7 pGCA_001717605_00197 - 0.18 11.4 0.9 0.32 10.6 0.5 1.6 2 0 0 2 2 2 0 YvrJ protein family Relaxase PF03432.14 pGCA_001717605_00198 - 3.2e-15 56.4 0.9 3.2e-15 56.4 0.9 2.8 1 1 1 2 2 2 1 Relaxase/Mobilisation nuclease domain EST1 PF10374.9 pGCA_001717605_00198 - 1.3 9.7 9.1 1.1 9.8 6.6 2.3 1 1 1 2 2 2 0 Telomerase activating protein Est1 KxDL PF10241.9 pGCA_001717605_00198 - 5.4 7.4 10.9 9.4 6.6 2.0 3.9 4 0 0 4 4 4 0 Uncharacterized conserved protein Rep_3 PF01051.21 pGCA_001717605_00199 - 3.7e-38 131.5 16.1 3.7e-38 131.5 16.1 1.8 2 0 0 2 2 2 1 Initiator Replication protein AAA_assoc_C PF09821.9 pGCA_001717605_00199 - 0.0035 17.9 0.6 0.012 16.1 0.2 2.1 2 1 0 2 2 2 1 C-terminal AAA-associated domain CopG_antitoxin PF12441.8 pGCA_001717605_00199 - 0.018 15.5 1.2 6.1 7.5 0.4 3.0 2 1 1 3 3 3 0 CopG antitoxin of type II toxin-antitoxin system Rep_3 PF01051.21 pGCA_001717605_00202 - 8.7e-42 143.4 10.2 1.6e-41 142.6 10.2 1.4 1 0 0 1 1 1 1 Initiator Replication protein SRPRB PF09439.10 pGCA_001717605_00202 - 0.036 13.5 0.3 0.068 12.6 0.3 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3791 PF12668.7 pGCA_001717605_00203 - 0.034 14.2 0.1 0.06 13.4 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3791) DASH_Spc34 PF08657.10 pGCA_001717605_00204 - 0.00061 19.7 13.7 0.00061 19.7 13.7 2.1 3 0 0 3 3 3 1 DASH complex subunit Spc34 TrbC PF04956.13 pGCA_001865595_00002 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_001865595_00002 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pGCA_001865595_00004 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_001865595_00004 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pGCA_001865595_00005 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_001865595_00005 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_001865595_00005 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_001865595_00005 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pGCA_001865595_00006 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001865595_00006 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001865595_00006 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_001865595_00006 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_001865595_00006 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_001865595_00006 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_001865595_00006 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 pGCA_001865595_00007 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pGCA_001865595_00008 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pGCA_001865595_00008 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pGCA_001865595_00008 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 pGCA_001865595_00009 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pGCA_001865595_00009 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pGCA_001865595_00009 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pGCA_001865595_00009 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 pGCA_001865595_00010 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pGCA_001865595_00010 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pGCA_001865595_00011 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_001865595_00011 - 0.074 13.0 0.3 0.33 10.9 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_001865595_00011 - 0.13 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_001865595_00011 - 0.27 11.9 5.3 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pGCA_001865595_00012 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) CdvA PF18822.1 pGCA_001865595_00014 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pGCA_001865595_00014 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pGCA_001865595_00014 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pGCA_001865595_00015 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_001865595_00015 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_001865595_00015 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pGCA_001865595_00015 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pGCA_001865595_00015 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pGCA_001865595_00016 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_19 PF12844.7 pGCA_001865595_00017 - 9.3e-06 25.6 0.1 0.016 15.3 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pGCA_001865595_00017 - 9.6e-06 25.6 0.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pGCA_001865595_00017 - 0.00071 19.6 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pGCA_001865595_00017 - 0.0073 15.8 0.0 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pGCA_001865595_00017 - 0.0089 16.1 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pGCA_001865595_00017 - 0.011 15.6 0.2 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pGCA_001865595_00017 - 0.017 14.9 0.0 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 pGCA_001865595_00017 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_31 PF13560.6 pGCA_001865595_00017 - 0.065 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 pGCA_001865595_00017 - 0.073 12.7 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain NYN PF01936.18 pGCA_001865595_00018 - 1.1e-09 38.9 1.0 4.7e-09 36.9 1.0 2.0 1 1 0 1 1 1 1 NYN domain SNF2_N PF00176.23 pGCA_001865595_00019 - 1.7e-16 59.9 1.1 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_001865595_00019 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_001865595_00019 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_001865595_00019 - 6.2e-06 26.1 1.6 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_001865595_00019 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pGCA_001865595_00020 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pGCA_001865595_00021 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001865595_00021 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001865595_00021 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_001865595_00021 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_001865595_00021 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pGCA_001865595_00022 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_001865595_00022 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pGCA_001865595_00023 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_001865595_00023 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_001865595_00023 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_001865595_00023 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_001865595_00023 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pGCA_001865595_00024 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_001865595_00024 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_001865595_00024 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_001865595_00024 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_001865595_00024 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_001865595_00024 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_001865595_00024 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pGCA_001865595_00025 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 pGCA_001865595_00026 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_001865595_00026 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pGCA_001865595_00027 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_001865595_00027 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain DUF5442 PF17514.2 pGCA_001865595_00029 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) GTP_EFTU PF00009.27 pGCA_001865595_00030 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_001865595_00030 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_001865595_00030 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_001865595_00030 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_001865595_00030 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_001865595_00030 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_001865595_00030 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_001865595_00030 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_001865595_00030 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pGCA_001865595_00032 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_001865595_00032 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pGCA_001865595_00033 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_001865595_00033 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_001865595_00033 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_001865595_00033 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_001865595_00033 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_001865595_00033 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_001865595_00033 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_001865595_00033 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_001865595_00033 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_001865595_00033 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_001865595_00033 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_001865595_00033 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_001865595_00033 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_001865595_00033 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_001865595_00033 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_001865595_00033 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_001865595_00033 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pGCA_001865595_00034 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pGCA_001865595_00036 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_001865595_00036 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_001865595_00036 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pGCA_001865595_00037 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pGCA_001865595_00038 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_001865595_00038 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_001865595_00038 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_001865595_00038 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pGCA_001865595_00039 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_001865595_00039 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_001865595_00039 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_001865595_00039 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pGCA_001865595_00040 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_001865595_00040 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_001865595_00040 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_001865595_00040 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_001865595_00040 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_001865595_00040 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_001865595_00040 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_001865595_00040 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_001865595_00040 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_001865595_00040 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_001865595_00040 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_001865595_00040 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_001865595_00040 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_001865595_00040 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_001865595_00040 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_001865595_00040 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_001865595_00040 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_001865595_00040 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_001865595_00040 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_001865595_00040 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_001865595_00040 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_001865595_00040 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_001865595_00040 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_001865595_00040 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_001865595_00040 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_001865595_00040 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_001865595_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_001865595_00040 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_001865595_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_001865595_00040 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_001865595_00040 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pGCA_001865595_00041 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_001865595_00041 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pGCA_001865595_00042 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_001865595_00042 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pGCA_001865595_00043 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_001865595_00043 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pGCA_001865595_00044 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_001865595_00044 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pGCA_001865595_00045 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_001865595_00045 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_001865595_00045 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pGCA_001865595_00046 - 1.6e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_001865595_00046 - 0.0055 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_001865595_00046 - 0.015 16.0 5.3 0.015 16.0 5.3 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pGCA_001865595_00046 - 0.018 15.7 1.0 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pGCA_001865595_00046 - 2.9 8.2 11.5 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pGCA_001865595_00046 - 5.1 7.2 14.8 0.55 10.3 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pGCA_001865595_00047 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_001865595_00047 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_001865595_00047 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_001865595_00047 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pGCA_001865595_00048 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 pGCA_001865595_00049 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pGCA_001865595_00049 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pGCA_001865595_00049 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pGCA_001865595_00049 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pGCA_001865595_00049 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pGCA_001865595_00049 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 pGCA_001865595_00050 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pGCA_001865595_00050 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pGCA_001865595_00050 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pGCA_001865595_00050 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pGCA_001865595_00050 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pGCA_001865595_00051 - 1.6e-28 100.2 0.0 4.5e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system HNOBA PF07701.14 pGCA_001865595_00051 - 0.022 14.2 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated cEGF PF12662.7 pGCA_001865595_00051 - 0.2 11.6 0.0 0.54 10.2 0.0 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like TrbC PF04956.13 pGCA_001865615_00003 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_001865615_00003 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pGCA_001865615_00005 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_001865615_00005 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pGCA_001865615_00006 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_001865615_00006 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_001865615_00006 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_001865615_00006 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pGCA_001865615_00007 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001865615_00007 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001865615_00007 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_001865615_00007 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_001865615_00007 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_001865615_00007 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_001865615_00007 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicB_lk_antitox PF15919.5 pGCA_001865615_00008 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system UBA_6 PF18039.1 pGCA_001865615_00011 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pGCA_001865615_00011 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pGCA_001865615_00011 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pGCA_001865615_00011 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF4223 PF13978.6 pGCA_001865615_00012 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pGCA_001865615_00012 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pGCA_001865615_00013 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_001865615_00013 - 0.074 13.0 0.3 0.33 10.9 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_001865615_00013 - 0.13 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_001865615_00013 - 0.27 11.9 5.3 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2400 PF09674.10 pGCA_001865615_00014 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) CdvA PF18822.1 pGCA_001865615_00016 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pGCA_001865615_00016 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pGCA_001865615_00016 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pGCA_001865615_00017 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_001865615_00017 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_001865615_00017 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pGCA_001865615_00017 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pGCA_001865615_00017 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pGCA_001865615_00018 - 2.1e-10 40.6 7.3 2.1e-10 40.6 7.3 2.6 1 1 1 2 2 2 1 Relaxase/Mobilisation nuclease domain Acetyltransf_7 PF13508.7 pGCA_001865615_00019 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_001865615_00019 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family SNF2_N PF00176.23 pGCA_001865615_00020 - 2.3e-16 59.4 3.3 2.7e-16 59.3 0.4 2.5 3 1 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_001865615_00020 - 3.3e-08 33.7 8.7 3.3e-08 33.7 8.7 4.1 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_001865615_00020 - 9.9e-07 29.1 1.8 2.7e-05 24.5 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_001865615_00020 - 1.4e-06 28.2 1.4 0.00061 19.6 0.3 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase BST2 PF16716.5 pGCA_001865615_00020 - 2.6 8.7 5.8 11 6.7 2.0 3.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Eco57I PF07669.11 pGCA_001865615_00021 - 5.7e-06 26.8 0.9 8e-05 23.1 0.2 2.8 2 0 0 2 2 2 1 Eco57I restriction-modification methylase MTS PF05175.14 pGCA_001865615_00021 - 0.0039 16.8 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 pGCA_001865615_00022 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pGCA_001865615_00023 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001865615_00023 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001865615_00023 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_001865615_00023 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_001865615_00023 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pGCA_001865615_00024 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_001865615_00024 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) NPA PF16469.5 pGCA_001865615_00025 - 0.02 15.5 5.1 0.025 15.1 5.1 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF4044 PF13253.6 pGCA_001865615_00026 - 0.012 15.1 1.1 0.019 14.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) DUF443 PF04276.12 pGCA_001865615_00026 - 0.013 15.3 6.9 0.014 15.2 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Claudin_2 PF13903.6 pGCA_001865615_00026 - 0.03 14.1 1.0 0.034 13.9 1.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Popeye PF04831.13 pGCA_001865615_00026 - 0.16 12.1 2.0 0.16 12.1 1.2 1.4 1 1 0 1 1 1 0 Popeye protein conserved region LysE PF01810.18 pGCA_001865615_00027 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_001865615_00027 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_001865615_00027 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_001865615_00027 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_001865615_00027 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_001865615_00027 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_001865615_00027 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pGCA_001865615_00028 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain CtsR_C PF17727.1 pGCA_001865615_00029 - 0.036 14.2 0.3 3.4 7.9 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pGCA_001865615_00030 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon APH PF01636.23 pGCA_001865615_00031 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pGCA_001865615_00031 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pGCA_001865615_00031 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Peptidase_C15 PF01470.17 pGCA_001865615_00032 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pGCA_001865615_00033 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_001865615_00033 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pGCA_001865615_00033 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pGCA_001865615_00033 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pGCA_001865615_00033 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pGCA_001865615_00033 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_18 PF13238.6 pGCA_001865615_00034 - 1.5e-06 28.8 0.0 2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pGCA_001865615_00034 - 3.5e-06 27.0 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pGCA_001865615_00034 - 0.0018 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pGCA_001865615_00034 - 0.088 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication GTP_EFTU PF00009.27 pGCA_001865615_00035 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_001865615_00035 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_001865615_00035 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_001865615_00035 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_001865615_00035 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_001865615_00035 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_001865615_00035 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_001865615_00035 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_001865615_00035 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family PcfJ PF14284.6 pGCA_001865615_00037 - 0.00071 19.5 1.8 0.0021 18.0 1.8 1.8 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_001865615_00037 - 0.033 14.1 2.9 0.25 11.3 2.9 2.4 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pGCA_001865615_00039 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_001865615_00039 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_001865615_00039 - 1.4e-08 34.4 15.0 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_001865615_00039 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_001865615_00039 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_001865615_00039 - 0.028 14.8 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pGCA_001865615_00039 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_001865615_00039 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_001865615_00039 - 0.088 12.7 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_001865615_00039 - 0.089 13.1 4.5 0.89 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_001865615_00039 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_001865615_00039 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_001865615_00039 - 0.64 10.0 3.8 4.6 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_001865615_00039 - 0.76 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_001865615_00039 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_001865615_00039 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pGCA_001865615_00040 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pGCA_001865615_00042 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_001865615_00042 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_001865615_00042 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pGCA_001865615_00043 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pGCA_001865615_00044 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_001865615_00044 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_001865615_00044 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_001865615_00044 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pGCA_001865615_00045 - 6.6e-104 348.3 0.0 1e-103 347.7 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_001865615_00045 - 6.6e-25 87.5 0.0 1.5e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_001865615_00045 - 9.9e-15 54.3 0.0 8.6e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_001865615_00045 - 0.037 14.2 0.1 0.084 13.0 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pGCA_001865615_00047 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_001865615_00047 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_001865615_00047 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_001865615_00047 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_001865615_00047 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_001865615_00047 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_001865615_00047 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_001865615_00047 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_001865615_00047 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_001865615_00047 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_001865615_00047 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_001865615_00047 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_001865615_00047 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_001865615_00047 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_001865615_00047 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_001865615_00047 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_001865615_00047 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_001865615_00047 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_001865615_00047 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_001865615_00047 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_001865615_00047 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_001865615_00047 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_001865615_00047 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_001865615_00047 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_001865615_00047 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_001865615_00047 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_001865615_00047 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_001865615_00047 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_001865615_00047 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_001865615_00047 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_001865615_00047 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pGCA_001865615_00048 - 3.1e-48 164.1 0.1 5.4e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_001865615_00048 - 0.028 13.5 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pGCA_001865615_00049 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_001865615_00049 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pGCA_001865615_00050 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_001865615_00050 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pGCA_001865615_00051 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_001865615_00051 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pGCA_001865615_00052 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_001865615_00052 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_001865615_00052 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pGCA_001865615_00053 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_001865615_00053 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_001865615_00053 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pGCA_001865615_00053 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pGCA_001865615_00053 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pGCA_001865615_00053 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pGCA_001865615_00053 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pGCA_001865615_00053 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pGCA_001865615_00054 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_001865615_00054 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_001865615_00054 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_001865615_00054 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pGCA_001865615_00055 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3251 PF11622.8 pGCA_001865615_00056 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pGCA_001865615_00056 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pGCA_001865615_00056 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pGCA_001865615_00056 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pGCA_001865615_00056 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pGCA_001865615_00056 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Phage_pRha PF09669.10 pGCA_001865615_00057 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pGCA_001865615_00057 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pGCA_001865615_00057 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pGCA_001865615_00057 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pGCA_001865615_00057 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 bZIP_1 PF00170.21 pGCA_001865615_00058 - 0.68 10.1 5.2 5 7.3 0.5 2.4 2 0 0 2 2 2 0 bZIP transcription factor IMS PF00817.20 pGCA_001936355_00001 - 1.1e-06 28.7 0.1 3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family DUF4368 PF14287.6 pGCA_001936355_00002 - 3.6e-23 81.6 2.1 1.2e-22 80.0 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Recombinase PF07508.13 pGCA_001936355_00002 - 3.6e-22 78.7 0.7 1.4e-21 76.9 0.2 2.3 2 0 0 2 2 2 1 Recombinase Resolvase PF00239.21 pGCA_001936355_00002 - 5.2e-21 75.3 0.1 5.2e-21 75.3 0.1 3.5 3 1 0 3 3 3 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 pGCA_001936355_00002 - 1.4e-12 47.9 2.6 4.3e-12 46.3 2.6 1.9 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Xrn1_D3 PF18194.1 pGCA_001936355_00002 - 0.12 12.5 0.5 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 TnpV PF14198.6 pGCA_001936355_00003 - 3.3e-41 139.8 0.5 3.6e-41 139.6 0.5 1.0 1 0 0 1 1 1 1 Transposon-encoded protein TnpV AAA_18 PF13238.6 pGCA_001936355_00004 - 1.2e-14 55.0 0.0 1.5e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pGCA_001936355_00004 - 2.4e-11 44.0 0.0 2.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pGCA_001936355_00004 - 2.8e-10 40.3 0.0 5.4e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 pGCA_001936355_00004 - 1.5e-07 30.9 0.0 3.1e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 pGCA_001936355_00004 - 3.6e-06 27.3 0.2 9.9e-06 25.9 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 pGCA_001936355_00004 - 8.3e-06 26.3 0.0 5.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 pGCA_001936355_00004 - 8.6e-06 26.2 0.0 3.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pGCA_001936355_00004 - 1.5e-05 25.3 0.0 5.4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pGCA_001936355_00004 - 5.9e-05 23.1 0.0 8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pGCA_001936355_00004 - 0.00029 21.2 0.0 0.00036 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pGCA_001936355_00004 - 0.00097 18.5 0.3 0.0011 18.2 0.3 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 pGCA_001936355_00004 - 0.0016 18.8 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 pGCA_001936355_00004 - 0.0016 18.0 0.1 0.0034 16.9 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 pGCA_001936355_00004 - 0.0021 17.8 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_001936355_00004 - 0.0022 17.8 0.3 0.0036 17.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pGCA_001936355_00004 - 0.0025 18.3 0.0 0.0029 18.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.13 pGCA_001936355_00004 - 0.0047 16.2 0.3 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain APS_kinase PF01583.20 pGCA_001936355_00004 - 0.0047 16.8 0.0 0.088 12.7 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase ATPase PF06745.13 pGCA_001936355_00004 - 0.0061 15.9 0.7 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 KaiC T2SSE PF00437.20 pGCA_001936355_00004 - 0.011 14.9 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DnaB_C PF03796.15 pGCA_001936355_00004 - 0.015 14.7 0.5 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 pGCA_001936355_00004 - 0.015 14.9 0.1 0.033 13.8 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 pGCA_001936355_00004 - 0.015 15.2 0.1 0.93 9.4 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 pGCA_001936355_00004 - 0.016 15.1 0.5 0.031 14.2 0.2 1.6 2 0 0 2 2 1 0 NTPase Viral_helicase1 PF01443.18 pGCA_001936355_00004 - 0.016 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 pGCA_001936355_00004 - 0.018 14.8 0.1 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 pGCA_001936355_00004 - 0.018 14.6 0.3 0.066 12.8 0.1 2.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 pGCA_001936355_00004 - 0.024 14.8 0.2 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.15 pGCA_001936355_00004 - 0.03 14.3 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain Hydin_ADK PF17213.3 pGCA_001936355_00004 - 0.032 14.5 0.7 0.05 13.9 0.2 1.5 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain NB-ARC PF00931.22 pGCA_001936355_00004 - 0.037 13.2 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MKT1_N PF12247.8 pGCA_001936355_00004 - 0.04 14.3 0.0 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication ArsA_ATPase PF02374.15 pGCA_001936355_00004 - 0.042 13.0 0.1 0.089 12.0 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase NACHT PF05729.12 pGCA_001936355_00004 - 0.045 13.7 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 pGCA_001936355_00004 - 0.046 13.5 1.0 0.067 13.0 0.9 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 pGCA_001936355_00004 - 0.047 14.1 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 pGCA_001936355_00004 - 0.053 13.2 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GvpD PF07088.11 pGCA_001936355_00004 - 0.054 12.1 0.3 0.38 9.3 0.0 2.1 2 1 1 3 3 3 0 GvpD gas vesicle protein AAA_7 PF12775.7 pGCA_001936355_00004 - 0.056 13.0 0.2 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 pGCA_001936355_00004 - 0.073 12.8 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 pGCA_001936355_00004 - 0.076 12.5 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase1 PF18748.1 pGCA_001936355_00004 - 0.086 12.4 0.0 2 7.9 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 ATP-synt_ab PF00006.25 pGCA_001936355_00004 - 0.086 12.5 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IPT PF01745.16 pGCA_001936355_00004 - 0.098 12.0 0.2 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 Isopentenyl transferase Ploopntkinase3 PF18751.1 pGCA_001936355_00004 - 0.11 12.4 0.4 0.37 10.7 0.0 2.0 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 pGCA_001936355_00004 - 0.18 11.5 0.7 10 5.7 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase APH PF01636.23 pGCA_001936355_00005 - 8.6e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_001936355_00005 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pGCA_001936355_00005 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pGCA_001936355_00005 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pGCA_001936355_00005 - 0.09 12.4 0.4 0.15 11.6 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pGCA_001936355_00005 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pGCA_001936355_00006 - 1.3e-51 175.6 0.1 1.5e-51 175.5 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pGCA_001936355_00007 - 6.8e-11 42.6 0.0 8.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_001936355_00007 - 0.014 14.6 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase CPT PF07931.12 pGCA_001936355_00008 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 pGCA_001936355_00008 - 9.4e-06 26.2 0.0 1.2e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pGCA_001936355_00008 - 0.00063 19.9 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MKT1_N PF12247.8 pGCA_001936355_00008 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_17 PF13207.6 pGCA_001936355_00008 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3847 PF12958.7 pGCA_001936355_00009 - 1.8e-31 108.1 8.2 2.6e-31 107.6 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) CENP-Q PF13094.6 pGCA_001936355_00009 - 0.034 14.3 11.9 0.044 14.0 11.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_8 PF13181.6 pGCA_001936355_00009 - 0.078 13.2 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 pGCA_001936355_00009 - 4.2 7.6 7.2 6.6 6.9 7.2 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MobA_MobL PF03389.15 pGCA_001936355_00010 - 3.5e-50 170.8 0.0 3.9e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 MobA/MobL family AAA_25 PF13481.6 pGCA_001936355_00011 - 4.9e-30 104.5 0.0 8.9e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 pGCA_001936355_00011 - 6.6e-18 64.9 0.0 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Toprim-like DUF3991 PF13154.6 pGCA_001936355_00011 - 3.3e-14 53.0 0.0 1.7e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3991) DnaB_C PF03796.15 pGCA_001936355_00011 - 8.6e-09 35.1 0.0 4.9e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Toprim_3 PF13362.6 pGCA_001936355_00011 - 1.8e-08 34.6 0.2 4.4e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 pGCA_001936355_00011 - 7.2e-06 25.5 0.1 0.0002 20.8 0.0 2.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 pGCA_001936355_00011 - 0.0002 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 pGCA_001936355_00011 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Toprim_4 PF13662.6 pGCA_001936355_00011 - 0.0078 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain AAA_5 PF07728.14 pGCA_001936355_00011 - 0.018 15.0 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad51 PF08423.11 pGCA_001936355_00011 - 0.05 12.8 0.0 0.54 9.5 0.0 2.2 1 1 0 1 1 1 0 Rad51 Toprim PF01751.22 pGCA_001936355_00011 - 0.051 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_11 PF13086.6 pGCA_001936355_00011 - 0.065 13.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 pGCA_001936355_00011 - 0.13 12.7 0.0 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 pGCA_001936355_00011 - 0.17 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-CHC2 PF01807.20 pGCA_001936355_00011 - 0.18 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 CHC2 zinc finger DUF2075 PF09848.9 pGCA_001936355_00011 - 0.2 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IMS_C PF11799.8 pGCA_001936355_00012 - 1.1e-12 48.7 0.0 1.9e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 pGCA_001936355_00012 - 0.00028 21.0 0.1 0.00067 19.8 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF447 PF04289.12 pGCA_001936355_00014 - 0.029 14.2 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) WH1 PF00568.23 pGCA_001936355_00014 - 0.032 14.1 0.3 0.049 13.6 0.2 1.4 1 1 0 1 1 1 0 WH1 domain Cob_adeno_trans PF01923.18 pGCA_001936355_00014 - 0.04 14.0 0.1 0.054 13.6 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3825 PF12873.7 pGCA_001936355_00015 - 4.2e-29 101.7 0.3 6.7e-29 101.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3825) SGT1 PF07093.11 pGCA_001936355_00017 - 0.046 12.2 2.7 0.045 12.2 2.7 1.0 1 0 0 1 1 1 0 SGT1 protein PG_binding_4 PF12229.8 pGCA_001936355_00017 - 0.057 13.7 1.0 0.065 13.5 1.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2175 PF09943.9 pGCA_001936355_00017 - 0.077 13.3 1.2 0.082 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5309 PF17236.2 pGCA_001936355_00018 - 3.1e-05 23.5 0.5 3.3e-05 23.4 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5309) HicA_toxin PF07927.12 pGCA_001936355_00019 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pGCA_001936355_00020 - 8.3e-09 35.6 0.3 0.00035 20.7 0.1 2.1 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 pGCA_001936355_00020 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ParE_toxin PF05016.15 pGCA_001936355_00022 - 1.1e-07 32.4 0.1 1.2e-07 32.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 pGCA_001936355_00024 - 8.9e-29 99.7 1.1 9.7e-29 99.5 1.1 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ DUF4131 PF13567.6 pGCA_001936355_00025 - 0.0008 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF981 PF06168.11 pGCA_001936355_00025 - 0.015 15.2 3.3 0.019 14.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Wzy_C PF04932.15 pGCA_001936355_00025 - 0.056 13.1 1.3 0.064 12.9 1.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2663 PF10864.8 pGCA_001936355_00025 - 0.13 12.7 2.1 0.16 12.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2721 PF11026.8 pGCA_001936355_00025 - 0.27 11.1 5.3 0.34 10.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TraG_N PF07916.11 pGCA_001936355_00026 - 8.5e-39 133.7 20.1 8.5e-39 133.7 20.1 3.3 3 1 0 4 4 4 1 TraG-like protein, N-terminal region Glyco_tranf_2_5 PF13712.6 pGCA_001936355_00027 - 0.00068 19.4 3.8 0.0013 18.5 3.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family UvrA_DNA-bind PF17755.1 pGCA_001936355_00028 - 0.00087 19.6 0.5 0.32 11.4 0.1 2.4 2 0 0 2 2 2 2 UvrA DNA-binding domain SseC PF04888.12 pGCA_001936355_00030 - 0.0051 16.5 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ThrE PF06738.12 pGCA_001936355_00030 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter APOBEC_C PF05240.14 pGCA_001936355_00030 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Hormone_2 PF00123.20 pGCA_001936355_00030 - 0.035 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone Phage_lysozyme PF00959.19 pGCA_001936355_00032 - 1.2e-10 41.8 1.2 1.9e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Phage lysozyme Vta1 PF04652.16 pGCA_001936355_00032 - 2.2 8.3 10.2 0.054 13.5 1.0 2.9 3 1 1 4 4 4 0 Vta1 like DUF2974 PF11187.8 pGCA_001936355_00033 - 1.4e-06 28.0 0.0 3.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 pGCA_001936355_00033 - 1e-05 25.4 0.0 4.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 pGCA_001936355_00033 - 0.0019 17.7 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pGCA_001936355_00033 - 0.0036 17.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF4450 PF14614.6 pGCA_001936355_00033 - 0.016 14.8 0.2 0.047 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4450) UPF0227 PF05728.12 pGCA_001936355_00033 - 0.028 14.4 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAF-AH_p_II PF03403.13 pGCA_001936355_00033 - 0.028 13.0 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 pGCA_001936355_00033 - 0.049 14.2 0.0 0.069 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 pGCA_001936355_00034 - 0.0024 17.4 0.1 0.007 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pGCA_001936355_00034 - 0.05 13.1 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 pGCA_001936355_00034 - 0.11 12.3 0.1 0.44 10.4 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 3) DUF3810 PF12725.7 pGCA_001936355_00035 - 0.0026 17.2 5.2 0.0029 17.0 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) CitMHS PF03600.16 pGCA_001936355_00035 - 0.023 13.9 0.3 0.023 13.9 0.3 1.0 1 0 0 1 1 1 0 Citrate transporter Yip1 PF04893.17 pGCA_001936355_00035 - 0.11 12.2 5.7 0.16 11.7 5.7 1.1 1 0 0 1 1 1 0 Yip1 domain Spo7 PF03907.13 pGCA_001936355_00035 - 1.8 7.9 10.7 4.1 6.8 10.3 1.8 1 1 0 1 1 1 0 Spo7-like protein Lipase_3 PF01764.25 pGCA_001936355_00038 - 1.5e-08 34.6 0.0 5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 pGCA_001936355_00038 - 3.1e-08 33.4 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 pGCA_001936355_00038 - 1.1e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 pGCA_001936355_00038 - 5.6e-05 23.0 0.1 9.7e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 pGCA_001936355_00038 - 0.00041 20.0 0.1 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 pGCA_001936355_00038 - 0.00064 20.4 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 pGCA_001936355_00038 - 0.0014 18.6 0.3 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 pGCA_001936355_00038 - 0.014 15.3 1.8 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase NMT PF01233.19 pGCA_001936355_00038 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Hydrolase_4 PF12146.8 pGCA_001936355_00038 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 pGCA_001936355_00038 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Put_DNA-bind_N PF06971.13 pGCA_001936355_00042 - 0.039 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus ATG27 PF09451.10 pGCA_001936355_00042 - 0.071 13.0 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Toprim_3 PF13362.6 pGCA_001936355_00044 - 2.4e-08 34.2 0.1 6.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pGCA_001936355_00044 - 0.017 15.4 0.2 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein DUF2315 PF10231.9 pGCA_001936355_00044 - 0.023 14.8 6.8 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 Apoptogenic protein 1 5_3_exonuc PF01367.20 pGCA_001936355_00044 - 0.25 12.0 1.7 0.53 10.9 0.2 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Abi_2 PF07751.11 pGCA_001936355_00045 - 0.0013 19.1 11.1 0.002 18.4 11.1 1.3 1 0 0 1 1 1 1 Abi-like protein NYN PF01936.18 pGCA_001936355_00046 - 1.7e-10 41.6 0.0 1.9e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 NYN domain Peroxin-22 PF12827.7 pGCA_001936355_00046 - 0.0082 16.0 0.7 0.016 15.1 0.7 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family PIN7 PF18475.1 pGCA_001936355_00046 - 0.02 15.5 0.0 0.035 14.8 0.0 1.4 1 0 0 1 1 1 0 PIN domain RHH_7 PF16777.5 pGCA_001936355_00047 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pGCA_001936355_00047 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 pGCA_001936355_00048 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001936355_00048 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001936355_00048 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pGCA_001936355_00048 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF4223 PF13978.6 pGCA_001936355_00049 - 0.21 11.6 1.5 0.36 10.8 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) ZapB PF06005.12 pGCA_001936355_00050 - 0.094 13.2 0.1 0.095 13.2 0.1 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF1451 PF07295.11 pGCA_001936355_00051 - 0.00056 20.0 0.0 0.00063 19.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain DUF4145 PF13643.6 pGCA_001936355_00052 - 8.2e-17 61.1 3.4 1.4e-15 57.1 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4145) HicB_lk_antitox PF15919.5 pGCA_001936355_00054 - 1.8e-08 34.5 0.0 2e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pGCA_001936355_00054 - 0.075 12.4 0.0 0.082 12.3 0.0 1.0 1 0 0 1 1 1 0 IRSp53/MIM homology domain HicA_toxin PF07927.12 pGCA_001936355_00055 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_001936355_00056 - 1.7e-15 57.2 0.0 3.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_001936355_00056 - 0.00066 19.1 0.0 0.0072 15.7 0.0 2.2 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_001936355_00056 - 0.0016 18.2 0.0 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pGCA_001936355_00056 - 0.0031 17.3 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pGCA_001936355_00056 - 0.0057 16.0 0.1 0.044 13.1 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pGCA_001936355_00056 - 0.07 13.6 0.7 0.9 10.0 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pGCA_001936355_00056 - 0.16 12.0 1.2 0.59 10.2 1.2 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1947 PF09183.10 pGCA_001936355_00056 - 0.7 10.2 6.3 1.7 9.0 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) RHH_7 PF16777.5 pGCA_001936355_00057 - 6.1e-06 26.5 1.0 6.9e-06 26.4 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG UXS1_N PF11803.8 pGCA_001936355_00057 - 0.03 14.7 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA_31 PF13614.6 pGCA_001936355_00058 - 6.9e-05 22.8 0.5 0.00093 19.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_001936355_00058 - 0.001 19.1 0.5 0.0086 16.1 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_001936355_00058 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pGCA_001936355_00058 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF4995 PF16386.5 pGCA_001936355_00059 - 0.14 12.2 0.7 0.15 12.1 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF4223 PF13978.6 pGCA_001936355_00059 - 0.2 11.6 1.9 0.28 11.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) CitMHS PF03600.16 pGCA_001936355_00064 - 0.0018 17.5 0.1 0.0018 17.5 0.1 1.0 1 0 0 1 1 1 1 Citrate transporter DUF3810 PF12725.7 pGCA_001936355_00064 - 0.0049 16.3 5.3 0.0058 16.0 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Yip1 PF04893.17 pGCA_001936355_00064 - 0.24 11.1 5.6 0.37 10.5 5.6 1.2 1 0 0 1 1 1 0 Yip1 domain Ion_trans PF00520.31 pGCA_001936355_00064 - 1.4 8.1 14.4 1.7 7.8 14.4 1.5 1 1 0 1 1 1 0 Ion transport protein DHHC PF01529.20 pGCA_001936355_00064 - 1.8 8.6 10.9 3.1 7.9 10.9 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Spo7 PF03907.13 pGCA_001936355_00064 - 2.8 7.4 6.8 5.6 6.4 6.8 1.5 1 0 0 1 1 1 0 Spo7-like protein CitMHS PF03600.16 pGCA_001936355_00066 - 0.0033 16.7 0.5 0.0039 16.4 0.5 1.1 1 0 0 1 1 1 1 Citrate transporter Yip1 PF04893.17 pGCA_001936355_00066 - 0.4 10.4 6.1 0.57 9.9 6.1 1.1 1 0 0 1 1 1 0 Yip1 domain DUF3810 PF12725.7 pGCA_001936355_00066 - 0.43 9.9 11.7 0.55 9.5 11.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Ion_trans PF00520.31 pGCA_001936355_00066 - 0.5 9.5 12.3 0.78 8.9 12.2 1.4 1 1 0 1 1 1 0 Ion transport protein Spo7 PF03907.13 pGCA_001936355_00066 - 2.2 7.7 7.5 3.7 7.0 7.5 1.5 1 1 0 1 1 1 0 Spo7-like protein DHHC PF01529.20 pGCA_001936355_00066 - 3.4 7.8 11.8 6.4 6.9 11.8 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Phage_lysozyme PF00959.19 pGCA_001936355_00067 - 2.1e-10 41.0 2.1 6e-10 39.6 0.1 2.9 2 0 0 2 2 2 1 Phage lysozyme Lipase_3 PF01764.25 pGCA_001936355_00067 - 2.8e-07 30.5 0.0 1e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 pGCA_001936355_00067 - 0.00084 19.1 2.0 0.003 17.3 0.0 2.8 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 pGCA_001936355_00067 - 0.096 13.3 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 pGCA_001936355_00067 - 0.2 11.8 0.0 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain SseC PF04888.12 pGCA_001936355_00069 - 0.014 15.1 0.2 0.014 15.1 0.2 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ThrE PF06738.12 pGCA_001936355_00069 - 0.014 14.8 0.8 0.035 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative threonine/serine exporter APOBEC_C PF05240.14 pGCA_001936355_00069 - 0.018 15.0 0.5 0.091 12.7 0.5 2.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Hormone_2 PF00123.20 pGCA_001936355_00069 - 0.035 14.0 0.1 0.16 11.9 0.1 2.3 1 0 0 1 1 1 0 Peptide hormone UvrA_DNA-bind PF17755.1 pGCA_001936355_00070 - 0.0051 17.1 0.3 3.2 8.1 0.0 2.8 3 0 0 3 3 3 2 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 pGCA_001936355_00071 - 0.013 15.8 0.2 6.8 7.1 0.1 2.6 2 0 0 2 2 2 0 UvrA DNA-binding domain UvrA_DNA-bind PF17755.1 pGCA_001936355_00073 - 0.025 14.9 0.6 11 6.4 0.1 2.7 3 0 0 3 3 3 0 UvrA DNA-binding domain DUF3870 PF12986.7 pGCA_001936355_00073 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) FHA PF00498.26 pGCA_001936355_00074 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 pGCA_001936355_00074 - 0.0007 19.9 0.0 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FDX-ACB PF03147.14 pGCA_001936355_00074 - 0.05 14.0 3.1 0.44 11.0 0.9 2.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain ImcF-related_N PF14331.6 pGCA_001936355_00075 - 6.2e-41 140.5 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF_C PF06744.12 pGCA_001936355_00075 - 5.9e-40 137.0 0.5 1.1e-39 136.2 0.5 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal IcmF-related PF06761.12 pGCA_001936355_00075 - 8.2e-27 94.5 2.1 1.3e-26 93.9 2.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing RsgA_GTPase PF03193.16 pGCA_001936355_00075 - 0.0003 20.7 0.0 0.023 14.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 pGCA_001936355_00075 - 0.0011 19.0 0.1 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Wzy_C PF04932.15 pGCA_001936355_00075 - 0.0033 17.1 5.0 0.037 13.7 0.4 3.5 3 0 0 3 3 3 1 O-Antigen ligase AAA_29 PF13555.6 pGCA_001936355_00075 - 0.055 13.2 0.1 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain T6SS_HCP PF05638.12 pGCA_001936355_00076 - 5.7e-30 104.4 0.1 6.5e-30 104.2 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp DotU PF09850.9 pGCA_001936355_00077 - 3.6e-35 121.5 0.0 4.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system protein DotU T6SS_VasE PF05936.12 pGCA_001936355_00078 - 1.3e-112 376.6 0.0 1.5e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE T6SS-SciN PF12790.7 pGCA_001936355_00079 - 1.9e-14 53.4 0.2 2.1e-14 53.3 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 T6SS_VasJ PF16989.5 pGCA_001936355_00080 - 1.2e-12 47.9 0.0 1.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ImpA_N PF06812.12 pGCA_001936355_00080 - 0.00014 22.0 0.2 0.0008 19.5 0.1 2.0 2 0 0 2 2 2 1 ImpA, N-terminal, type VI secretion system PX PF00787.24 pGCA_001936355_00080 - 0.074 13.0 14.5 1.1 9.2 2.4 4.2 3 2 0 3 3 3 0 PX domain TetR_C_24 PF17932.1 pGCA_001936355_00080 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain T6SS_VipA PF05591.12 pGCA_001936355_00081 - 6.4e-52 175.5 3.9 7.2e-52 175.3 3.9 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 Chitin_synth_2 PF03142.15 pGCA_001936355_00081 - 0.14 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase VipB PF05943.12 pGCA_001936355_00082 - 7.4e-170 565.3 0.0 8.7e-170 565.1 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath PBS_linker_poly PF00427.21 pGCA_001936355_00082 - 0.33 11.0 2.6 18 5.4 0.0 3.1 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide GPW_gp25 PF04965.14 pGCA_001936355_00083 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Dynactin_p22 PF07426.11 pGCA_001936355_00083 - 0.0076 16.1 0.3 0.0097 15.8 0.3 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Dot_icm_IcmQ PF09475.10 pGCA_001936355_00083 - 0.051 13.0 0.1 0.12 11.8 0.1 1.7 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) T6SS_TssF PF05947.12 pGCA_001936355_00084 - 2.3e-110 369.9 0.0 2.6e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF T6SS_TssG PF06996.11 pGCA_001936355_00085 - 1.9e-47 161.9 0.0 2.2e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG Phage_GPD PF05954.11 pGCA_001936355_00086 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 pGCA_001936355_00086 - 0.011 15.7 1.7 0.029 14.2 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) Gp5_C PF06715.12 pGCA_001936355_00086 - 0.013 15.6 4.6 0.19 11.9 0.1 4.0 2 1 2 4 4 4 0 Gp5 C-terminal repeat (3 copies) DUF3540 PF12059.8 pGCA_001936355_00086 - 0.1 12.4 0.8 0.45 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3540) TCL1_MTCP1 PF01840.17 pGCA_001936355_00086 - 0.1 12.2 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 TCL1/MTCP1 family Ank_3 PF13606.6 pGCA_001936355_00087 - 2.8e-10 39.5 0.1 0.00091 19.5 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 pGCA_001936355_00087 - 3.8e-09 37.0 0.0 2.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 pGCA_001936355_00087 - 1.9e-05 25.1 0.0 0.0011 19.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 pGCA_001936355_00087 - 7.3e-05 23.0 0.0 2.5 8.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 pGCA_001936355_00087 - 0.0034 17.6 0.3 0.13 12.7 0.0 3.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pGCA_001936355_00088 - 6.6e-08 32.8 0.0 6.6e-08 32.8 0.0 3.0 2 1 1 3 3 3 1 Restriction endonuclease fold toxin 7 Ank_2 PF12796.7 pGCA_001936355_00089 - 1.3e-11 44.9 0.5 1.1e-06 29.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pGCA_001936355_00089 - 4.9e-10 38.8 0.4 0.0091 16.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 pGCA_001936355_00089 - 0.0015 19.1 0.1 0.31 11.7 0.0 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 pGCA_001936355_00089 - 0.0038 17.6 0.0 18 6.0 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 pGCA_001936355_00089 - 0.023 15.0 0.1 1.5 9.2 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Tox-REase-7 PF15649.6 pGCA_001936355_00090 - 1.4e-07 31.7 4.9 1.7e-07 31.5 0.0 3.6 2 1 1 3 3 3 1 Restriction endonuclease fold toxin 7 DUF2239 PF09998.9 pGCA_001936355_00090 - 0.57 9.9 6.5 1.6 8.5 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Ank_2 PF12796.7 pGCA_001936355_00091 - 5.5e-13 49.3 0.5 1.3e-07 32.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 pGCA_001936355_00091 - 5.8e-11 41.6 0.3 0.00054 20.2 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 pGCA_001936355_00091 - 1.9e-05 24.9 0.0 1.1 9.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 pGCA_001936355_00091 - 6.7e-05 23.4 0.2 0.018 15.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FAM25 PF15825.5 pGCA_001936355_00091 - 0.0037 17.6 1.6 2.4 8.6 0.2 2.7 2 0 0 2 2 2 2 FAM25 family Ank_5 PF13857.6 pGCA_001936355_00091 - 0.028 14.7 0.1 0.82 10.1 0.0 3.4 3 1 1 4 4 4 0 Ankyrin repeats (many copies) TNT PF14021.6 pGCA_001936355_00094 - 1.5e-15 57.5 0.0 1.1e-08 35.5 0.0 2.3 2 0 0 2 2 2 2 Tuberculosis necrotizing toxin LPD7 PF18821.1 pGCA_001936355_00095 - 0.032 14.3 0.5 3.1 8.0 0.1 2.4 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 7 Imm59 PF15597.6 pGCA_001936355_00095 - 1.1 9.8 8.9 1.5 9.4 2.6 3.0 1 1 2 3 3 3 0 Immunity protein 59 AHH PF14412.6 pGCA_001936355_00096 - 1e-15 57.8 1.5 2e-15 56.9 1.5 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Ntox24 PF15529.6 pGCA_001936355_00099 - 0.003 17.8 1.3 0.0048 17.2 0.3 1.9 2 0 0 2 2 2 1 Bacterial toxin 24 CobN-Mg_chel PF02514.16 pGCA_001936355_00100 - 0.16 9.7 0.0 0.19 9.5 0.0 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Imm59 PF15597.6 pGCA_001936355_00101 - 0.054 14.0 8.6 0.12 12.9 1.7 2.2 1 1 1 2 2 2 0 Immunity protein 59 AHH PF14412.6 pGCA_001936355_00102 - 5.7e-17 61.8 2.0 1.1e-16 60.9 2.0 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RRF PF01765.19 pGCA_001936355_00102 - 0.25 11.3 7.2 0.13 12.2 1.5 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF4299 PF14132.6 pGCA_001936355_00104 - 1.4e-08 34.5 0.1 1.6e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) XPG_I PF00867.18 pGCA_001936355_00104 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 XPG I-region Phage_GPD PF05954.11 pGCA_001936355_00106 - 1.1e-17 64.3 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) TCL1_MTCP1 PF01840.17 pGCA_001936355_00106 - 0.081 12.6 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 TCL1/MTCP1 family BaxI_1 PF12811.7 pGCA_001936355_00108 - 0.28 10.7 13.0 0.43 10.1 12.5 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like CrgA PF06781.12 pGCA_001936355_00108 - 0.43 10.7 6.3 0.5 10.5 4.6 2.0 2 0 0 2 2 2 0 Cell division protein CrgA Peripla_BP_2 PF01497.18 pGCA_001936355_00109 - 0.017 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF2345 PF10106.9 pGCA_001936355_00109 - 0.029 14.3 0.4 0.27 11.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DZR PF12773.7 pGCA_001936355_00113 - 0.039 14.0 0.3 0.054 13.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.13 pGCA_001936355_00113 - 0.04 14.1 0.4 0.077 13.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zinc_ribbon_4 PF13717.6 pGCA_001936355_00113 - 0.6 10.1 4.6 0.64 10.0 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rapsyn_N PF10579.9 pGCA_001936355_00114 - 0.12 12.5 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SprT-like PF10263.9 pGCA_001936355_00116 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 pGCA_001936355_00116 - 0.077 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 IrrE N-terminal-like domain Phage_integrase PF00589.22 pGCA_001936355_00119 - 5.1e-24 85.0 0.5 8.3e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pGCA_001936355_00119 - 2.3e-05 24.6 3.9 0.00043 20.5 1.9 2.8 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pGCA_001936355_00119 - 0.00011 22.4 4.6 0.00011 22.4 4.6 2.6 3 0 0 3 3 3 1 Phage integrase SAM-like domain Phyto-Amp PF15438.6 pGCA_001936355_00119 - 0.0094 15.8 0.3 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma YbjN PF10722.9 pGCA_001936355_00119 - 0.011 15.8 0.3 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Phage_int_SAM_3 PF14659.6 pGCA_001936355_00119 - 0.028 14.7 3.2 0.11 12.8 3.2 2.1 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FlaC_arch PF05377.11 pGCA_001936355_00120 - 0.0083 16.5 2.3 0.0083 16.5 2.3 1.7 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) WGR PF05406.15 pGCA_001936355_00121 - 2.4e-07 30.7 0.6 2.7e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 WGR domain Cadherin_pro PF08758.11 pGCA_001936355_00121 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like YafQ_toxin PF15738.5 pGCA_001936355_00125 - 1.6e-26 92.4 3.7 2.1e-26 92.0 3.7 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ParE_toxin PF05016.15 pGCA_001936355_00125 - 1.9e-06 28.4 0.6 2.2e-06 28.2 0.6 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Ribosomal_S2 PF00318.20 pGCA_001936355_00125 - 0.0042 16.3 0.9 0.0053 16.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 ParE-like_toxin PF15781.5 pGCA_001936355_00125 - 0.017 15.1 1.6 0.035 14.1 1.6 1.6 1 1 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system CCDC-167 PF15188.6 pGCA_001936355_00130 - 0.0044 17.3 0.4 0.0077 16.6 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3461 PF11944.8 pGCA_001936355_00130 - 0.018 15.1 3.2 0.049 13.8 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) Sigma_reg_N PF13800.6 pGCA_001936355_00131 - 0.13 12.6 0.3 0.13 12.6 0.3 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5601 PF18151.1 pGCA_001936355_00132 - 0.038 14.3 0.2 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1640 PF07798.11 pGCA_001936355_00132 - 0.58 10.2 7.1 0.12 12.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) HTH_3 PF01381.22 pGCA_001936355_00134 - 8.4e-07 29.0 0.0 9.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 pGCA_001936355_00134 - 0.00022 21.6 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 pGCA_001936355_00134 - 0.0007 19.1 0.2 0.00093 18.7 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 pGCA_001936355_00134 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pGCA_001936355_00134 - 0.002 18.0 0.1 0.0023 17.7 0.1 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pGCA_001936355_00134 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 Homeodomain-like domain ENT PF03735.14 pGCA_001936355_00134 - 0.0035 17.4 0.3 0.0052 16.8 0.3 1.5 1 1 0 1 1 1 1 ENT domain HTH_31 PF13560.6 pGCA_001936355_00134 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 pGCA_001936355_00134 - 0.009 15.6 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 pGCA_001936355_00134 - 0.0098 16.2 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 pGCA_001936355_00134 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 pGCA_001936355_00134 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 pGCA_001936355_00134 - 0.02 14.7 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 pGCA_001936355_00134 - 0.029 14.2 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 pGCA_001936355_00134 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sigma70_r4 PF04545.16 pGCA_001936355_00134 - 0.034 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 pGCA_001936355_00134 - 0.081 13.1 0.1 7.6 6.8 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 pGCA_001936355_00134 - 0.085 12.7 0.0 9.3 6.1 0.0 2.1 1 1 1 2 2 2 0 MerR family regulatory protein Phage_terminase PF10668.9 pGCA_001936355_00134 - 0.15 12.1 0.2 0.33 11.0 0.2 1.6 1 1 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 pGCA_001936355_00134 - 0.2 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain GTP_EFTU PF00009.27 pGCA_002101355_00001 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_002101355_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_002101355_00001 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_002101355_00001 - 3e-12 46.4 0.1 6.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_002101355_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_002101355_00001 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_002101355_00001 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_002101355_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_002101355_00001 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 pGCA_002101355_00002 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pGCA_002101355_00002 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pGCA_002101355_00002 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 pGCA_002101355_00003 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pGCA_002101355_00004 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_002101355_00004 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 pGCA_002101355_00005 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_002101355_00005 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_002101355_00005 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pGCA_002101355_00005 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pGCA_002101355_00005 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pGCA_002101355_00005 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pGCA_002101355_00005 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_002101355_00005 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pGCA_002101355_00005 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pGCA_002101355_00006 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_002101355_00006 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_002101355_00006 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_002101355_00006 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_002101355_00006 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_002101355_00007 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_002101355_00007 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_002101355_00008 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_002101355_00008 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_002101355_00008 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_002101355_00008 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_002101355_00008 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pGCA_002101355_00009 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pGCA_002101355_00010 - 3e-16 59.1 2.6 4.1e-16 58.6 0.1 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_002101355_00010 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_002101355_00010 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_002101355_00010 - 8.9e-06 25.6 1.8 0.0012 18.6 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_002101355_00010 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pGCA_002101355_00011 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pGCA_002101355_00011 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pGCA_002101355_00011 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pGCA_002101355_00012 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_002101355_00012 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pGCA_002101355_00012 - 0.0083 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 pGCA_002101355_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_002101355_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_002101355_00014 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_002101355_00014 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pGCA_002101355_00014 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pGCA_002101355_00014 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pGCA_002101355_00015 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pGCA_002101355_00015 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pGCA_002101355_00015 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pGCA_002101355_00017 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pGCA_002101355_00018 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_002101355_00018 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_002101355_00018 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_002101355_00018 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_002101355_00019 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pGCA_002101355_00020 - 0.0019 18.2 0.5 0.0023 18.0 0.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pGCA_002101355_00020 - 0.14 12.5 3.0 0.19 12.1 3.0 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pGCA_002101355_00020 - 1.1 9.2 4.2 2 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pGCA_002101355_00022 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system AAA_25 PF13481.6 pGCA_002101355_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_002101355_00023 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_002101355_00023 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_002101355_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_002101355_00023 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_002101355_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_002101355_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pGCA_002101355_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_002101355_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_002101355_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_002101355_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pGCA_002101355_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_002101355_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pGCA_002101355_00027 - 3.4e-11 43.2 3.7 4e-11 43.0 3.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_002101355_00027 - 0.12 12.2 4.4 0.18 11.6 4.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_002101355_00028 - 1.7e-50 172.0 0.4 3.9e-50 170.8 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_002101355_00028 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pGCA_002101355_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pGCA_002101355_00029 - 6.6e-30 103.5 0.0 1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pGCA_002101355_00029 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DUF5512 PF17631.2 pGCA_002101355_00029 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) FapA PF03961.13 pGCA_002101355_00030 - 0.0039 15.9 6.9 0.0039 15.9 6.9 1.6 1 1 0 1 1 1 1 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 pGCA_002101355_00030 - 0.028 14.3 4.0 0.028 14.3 4.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Fib_alpha PF08702.10 pGCA_002101355_00030 - 0.6 10.3 12.2 0.061 13.5 4.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 pGCA_002101355_00030 - 1.7 8.4 11.6 0.92 9.3 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator Striatin PF08232.12 pGCA_002101355_00030 - 4.6 7.8 9.6 14 6.2 9.6 1.9 1 1 0 1 1 1 0 Striatin family Syntaxin-6_N PF09177.11 pGCA_002101355_00030 - 9.3 6.9 10.2 1.8 9.2 4.5 2.6 2 2 0 2 2 2 0 Syntaxin 6, N-terminal SSB PF00436.25 pGCA_002101355_00032 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_002101355_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_002101355_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_002101355_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_002101355_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pGCA_002101355_00034 - 8.6e-29 101.4 13.7 1.2e-28 100.9 13.7 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_002101355_00034 - 0.006 16.7 1.1 0.021 15.0 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pGCA_002101355_00034 - 0.018 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pGCA_002101355_00034 - 0.041 14.6 11.0 0.031 15.0 4.9 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3752 PF12572.8 pGCA_002101355_00034 - 1.4 9.5 6.4 9.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) THOC7 PF05615.13 pGCA_002101355_00034 - 2.8 8.2 12.1 1.7 9.0 0.2 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 Snapin_Pallidin PF14712.6 pGCA_002101355_00034 - 4.8 7.7 10.3 1.9 8.9 5.5 2.7 2 1 0 2 2 2 0 Snapin/Pallidin TrbL PF04610.14 pGCA_002101355_00035 - 3.3e-29 102.2 32.7 3.3e-29 102.2 32.7 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_002101355_00035 - 0.087 12.6 1.7 0.49 10.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_002101355_00035 - 1.7 9.6 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pGCA_002101355_00036 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_002101355_00036 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pGCA_002101355_00037 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_002101355_00037 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_002101355_00038 - 9.4e-56 188.9 1.6 1.6e-55 188.2 1.6 1.3 1 1 0 1 1 1 1 Conjugal transfer protein Rho_RNA_bind PF07497.12 pGCA_002101355_00038 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pGCA_002101355_00039 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_002101355_00039 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_002101355_00040 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_002101355_00040 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002101355_00040 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_002101355_00040 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_002101355_00040 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_002101355_00040 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pGCA_002101355_00040 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pGCA_002101355_00040 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_002101355_00040 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_002101355_00040 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_002101355_00040 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_002101355_00040 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pGCA_002101355_00040 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 pGCA_002101355_00040 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 pGCA_002101355_00040 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 pGCA_002101355_00040 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 pGCA_002101355_00040 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 pGCA_002101355_00040 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pGCA_002101355_00040 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 pGCA_002101355_00040 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pGCA_002101355_00040 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pGCA_002101355_00040 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_002101355_00040 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_002101355_00040 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_002101355_00040 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pGCA_002101355_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pGCA_002101355_00040 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pGCA_002101355_00040 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_002101355_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_002101355_00040 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_002101355_00040 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pGCA_002101355_00041 - 8.4e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002101355_00041 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002101355_00041 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pGCA_002101355_00041 - 0.19 11.8 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 pGCA_002101355_00042 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pGCA_002101355_00042 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pGCA_002101355_00043 - 2.4e-38 131.5 1.9 3.1e-38 131.2 1.9 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 pGCA_002101355_00043 - 0.21 10.6 0.1 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal PRELI PF04707.14 pGCA_002101355_00044 - 0.041 13.7 0.4 0.041 13.7 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Rsd_AlgQ PF04353.13 pGCA_002101355_00044 - 0.82 9.6 6.3 0.24 11.4 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ KH_5 PF13184.6 pGCA_002101355_00045 - 0.00035 20.6 0.5 0.00039 20.5 0.5 1.0 1 0 0 1 1 1 1 NusA-like KH domain CdhD PF03599.16 pGCA_002101355_00046 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 pGCA_002101355_00046 - 0.028 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 pGCA_002101355_00046 - 0.12 12.6 0.1 0.12 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized YnfE-like DUF1461 PF07314.11 pGCA_002101355_00047 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pGCA_002101355_00048 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_002101355_00048 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_002101355_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_002101355_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_002101355_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_002101355_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_002101355_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_002101355_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_002101355_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_002101355_00048 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_002101355_00048 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_002101355_00048 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_002101355_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_002101355_00048 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_002101355_00048 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_002101355_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_002101355_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pGCA_002101355_00049 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_002101355_00049 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain HicB_lk_antitox PF15919.5 pGCA_002209045_00002 - 3.6e-09 36.8 0.0 3.8e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system IMD PF08397.11 pGCA_002209045_00002 - 0.065 12.6 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain AAA_25 PF13481.6 pGCA_002209045_00003 - 1.7e-15 57.1 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_002209045_00003 - 0.00083 18.8 0.0 0.0041 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_002209045_00003 - 0.0013 18.5 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pGCA_002209045_00003 - 0.003 17.3 1.1 0.009 15.7 0.2 2.1 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 pGCA_002209045_00003 - 0.009 15.4 0.0 0.062 12.6 0.0 2.5 2 1 0 2 2 2 1 KaiC CbiA PF01656.23 pGCA_002209045_00003 - 0.19 11.8 1.3 0.63 10.1 1.3 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pGCA_002209045_00004 - 0.012 15.5 0.4 0.02 14.7 0.4 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pGCA_002209045_00006 - 2.4e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_002209045_00006 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_002209045_00006 - 0.051 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_002209045_00006 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pGCA_002209045_00007 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_002209045_00007 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pGCA_002209045_00009 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_002209045_00009 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_002209045_00010 - 7.6e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_002209045_00010 - 1.5e-20 73.2 1.0 2.6e-20 72.4 1.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pGCA_002209045_00010 - 3.8e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pGCA_002209045_00010 - 0.038 14.1 5.5 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pGCA_002209045_00011 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pGCA_002209045_00011 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pGCA_002209045_00011 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pGCA_002209045_00011 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pGCA_002209045_00011 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 pGCA_002209045_00012 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 pGCA_002209045_00013 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_002209045_00014 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_002209045_00014 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_002209045_00014 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_002209045_00014 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pGCA_002209045_00015 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_002209045_00015 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_002209045_00015 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pGCA_002209045_00015 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pGCA_002209045_00015 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 pGCA_002209045_00015 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 pGCA_002209045_00015 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pGCA_002209045_00015 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pGCA_002209045_00016 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_002209045_00016 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_002209045_00016 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pGCA_002209045_00017 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_002209045_00017 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pGCA_002209045_00018 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_002209045_00018 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_002209045_00019 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_002209045_00019 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pGCA_002209045_00020 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_002209045_00020 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_002209045_00021 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_002209045_00021 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002209045_00021 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_002209045_00021 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_002209045_00021 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_002209045_00021 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_002209045_00021 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_002209045_00021 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_002209045_00021 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_002209045_00021 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_002209045_00021 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_002209045_00021 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_002209045_00021 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_002209045_00021 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_002209045_00021 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_002209045_00021 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_002209045_00021 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_002209045_00021 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_002209045_00021 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_002209045_00021 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_002209045_00021 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_002209045_00021 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_002209045_00021 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_002209045_00021 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_002209045_00021 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_002209045_00021 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_002209045_00021 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_002209045_00021 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_002209045_00021 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_002209045_00021 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_002209045_00021 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pGCA_002209045_00022 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002209045_00022 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002209045_00022 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_002209045_00022 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pGCA_002209045_00023 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_002209045_00023 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_002209045_00023 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_002209045_00023 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pGCA_002209045_00024 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_002209045_00025 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_002209045_00025 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_002209045_00025 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pGCA_002209045_00027 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pGCA_002209045_00028 - 1.4e-97 327.4 8.2 1.9e-97 326.9 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_002209045_00028 - 3.7e-12 46.4 2.7 5.7e-12 45.8 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_002209045_00028 - 0.05 13.4 2.1 0.14 12.0 2.1 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_002209045_00028 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon EF-hand_8 PF13833.6 pGCA_002209045_00028 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pGCA_002209045_00028 - 0.34 11.1 3.3 0.78 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pGCA_002209045_00029 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_002209045_00029 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pGCA_002209045_00031 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_002209045_00031 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_002209045_00031 - 9.3e-17 60.9 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_002209045_00031 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_002209045_00031 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_002209045_00031 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_002209045_00031 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_002209045_00031 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_002209045_00031 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF5442 PF17514.2 pGCA_002209045_00032 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pGCA_002209045_00034 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_002209045_00034 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pGCA_002209045_00035 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_002209045_00035 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pGCA_002209045_00036 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pGCA_002209045_00037 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_002209045_00037 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_002209045_00037 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_002209045_00037 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_002209045_00037 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_002209045_00037 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_002209045_00037 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pGCA_002209045_00038 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_002209045_00038 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_002209045_00038 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_002209045_00038 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_002209045_00038 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_002209045_00039 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_002209045_00039 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_002209045_00040 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_002209045_00040 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_002209045_00040 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_002209045_00040 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_002209045_00040 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pGCA_002209045_00041 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pGCA_002209045_00042 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_002209045_00042 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_002209045_00042 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_002209045_00042 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_002209045_00042 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pGCA_002209045_00043 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_002209045_00043 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pGCA_002209045_00044 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_002209045_00045 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_002209045_00045 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_002209045_00045 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pGCA_002209045_00045 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pGCA_002209045_00045 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pGCA_002209045_00046 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pGCA_002209045_00046 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pGCA_002209045_00046 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pGCA_002209045_00049 - 2.4e-08 34.2 0.1 6.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pGCA_002209045_00049 - 0.016 15.4 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein 5_3_exonuc PF01367.20 pGCA_002209045_00049 - 0.33 11.6 2.5 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_002209045_00050 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pGCA_002209045_00050 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 STI1 domain TOPRIM_C PF16898.5 pGCA_002209045_00051 - 0.029 14.7 1.5 0.031 14.6 1.5 1.0 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Pkinase PF00069.25 pGCA_002209045_00052 - 4.3e-19 68.9 4.7 4.9e-19 68.7 4.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 pGCA_002209045_00052 - 3.7e-18 65.8 0.5 3.7e-18 65.8 0.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 pGCA_002209045_00052 - 1.3e-06 27.4 0.6 1.7e-06 27.1 0.6 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 pGCA_002209045_00052 - 0.072 12.4 0.0 0.21 10.9 0.0 1.7 1 1 1 2 2 2 0 Kinase-like LysE PF01810.18 pGCA_002214785_00001 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_002214785_00001 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_002214785_00001 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pGCA_002214785_00001 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pGCA_002214785_00001 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pGCA_002214785_00001 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pGCA_002214785_00001 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_002214785_00001 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pGCA_002214785_00001 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pGCA_002214785_00002 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_002214785_00002 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_002214785_00002 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_002214785_00002 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_002214785_00002 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_002214785_00003 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_002214785_00003 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_002214785_00004 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_002214785_00004 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_002214785_00004 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_002214785_00004 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_002214785_00004 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pGCA_002214785_00005 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pGCA_002214785_00006 - 3.5e-16 58.9 1.1 7.4e-16 57.8 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_002214785_00006 - 4e-08 33.4 8.0 4e-08 33.4 8.0 4.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_002214785_00006 - 1.2e-06 28.8 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_002214785_00006 - 5.8e-06 26.2 1.2 0.0013 18.5 0.2 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_002214785_00006 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pGCA_002214785_00007 - 0.0008 19.8 0.1 0.002 18.5 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2768 PF10966.8 pGCA_002214785_00007 - 0.011 16.1 0.9 0.026 15.0 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) Acetyltransf_1 PF00583.25 pGCA_002214785_00007 - 0.021 15.1 0.1 0.051 13.8 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GramPos_pilinBB PF16569.5 pGCA_002214785_00007 - 0.22 12.3 4.3 0.17 12.7 1.7 1.9 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain CooC_C PF15976.5 pGCA_002214785_00009 - 0.12 12.4 0.4 0.62 10.2 0.2 2.1 2 0 0 2 2 2 0 CS1-pili formation C-terminal EVI2A PF05399.11 pGCA_002214785_00009 - 2.8 7.5 10.5 6.1 6.4 10.5 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Peptidase_C39 PF03412.15 pGCA_002214785_00011 - 9e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pGCA_002214785_00011 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 pGCA_002214785_00011 - 0.086 13.4 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase_C39 like family Relaxase PF03432.14 pGCA_002214785_00013 - 1.6e-10 41.1 7.7 1.6e-10 41.1 7.7 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_002214785_00014 - 4.6e-05 23.3 7.5 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_002214785_00014 - 0.032 14.4 2.3 0.041 14.0 1.6 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_002214785_00014 - 0.1 12.7 5.3 1.5 8.9 0.3 2.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pGCA_002214785_00014 - 0.48 10.7 7.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pGCA_002214785_00015 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pGCA_002214785_00015 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pGCA_002214785_00015 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pGCA_002214785_00018 - 2.3e-08 34.3 0.2 6.4e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pGCA_002214785_00018 - 0.024 14.9 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Retrotransposon gag protein 5_3_exonuc PF01367.20 pGCA_002214785_00018 - 0.36 11.5 2.6 0.47 11.1 0.4 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_002214785_00019 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pGCA_002214785_00019 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 STI1 domain DUF1451 PF07295.11 pGCA_002214785_00020 - 0.00056 20.0 0.0 0.00063 19.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain DUF4145 PF13643.6 pGCA_002214785_00021 - 2.5e-16 59.6 5.0 1.4e-15 57.1 0.1 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4145) Glyco_hydro_16 PF00722.21 pGCA_002214785_00024 - 0.081 12.4 0.4 0.081 12.4 0.4 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 HicB_lk_antitox PF15919.5 pGCA_002214785_00025 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pGCA_002214785_00026 - 6.2e-11 42.2 0.3 7.4e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_002214785_00027 - 1.8e-15 57.0 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_002214785_00027 - 0.00087 18.7 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_002214785_00027 - 0.0012 18.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 pGCA_002214785_00027 - 0.0035 17.1 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pGCA_002214785_00027 - 0.011 15.1 0.1 0.064 12.6 0.0 2.4 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_002214785_00027 - 0.18 11.9 0.9 0.53 10.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GBR_NSP5 PF17580.2 pGCA_002214785_00028 - 0.012 15.5 0.4 0.02 14.7 0.4 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Resolvase PF00239.21 pGCA_002214785_00030 - 1.6e-33 115.9 0.7 2.1e-33 115.5 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_002214785_00030 - 0.024 14.4 0.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_002214785_00030 - 0.028 14.5 4.9 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_002214785_00030 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pGCA_002214785_00031 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_002214785_00031 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pGCA_002214785_00033 - 4.9e-14 52.3 5.8 5.6e-14 52.2 5.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_002214785_00033 - 0.59 10.0 6.1 1.3 8.9 6.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_002214785_00034 - 7.4e-52 176.4 0.8 1.9e-51 175.1 0.8 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_002214785_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pGCA_002214785_00034 - 3.9e-07 29.3 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pGCA_002214785_00034 - 0.033 14.3 5.2 1.8 8.6 0.0 4.0 4 2 1 5 5 5 0 Helicase HerA, central domain Phage_pRha PF09669.10 pGCA_002214785_00035 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pGCA_002214785_00035 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pGCA_002214785_00035 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pGCA_002214785_00035 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pGCA_002214785_00035 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3895 PF13034.6 pGCA_002214785_00036 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) SSB PF00436.25 pGCA_002214785_00037 - 7e-25 87.1 0.1 8.8e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_002214785_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_002214785_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_002214785_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_002214785_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pGCA_002214785_00039 - 4.7e-28 98.9 14.1 6.1e-28 98.6 14.1 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_002214785_00039 - 0.0059 16.7 0.7 0.02 15.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_002214785_00039 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pGCA_002214785_00039 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pGCA_002214785_00039 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Allexi_40kDa PF05549.11 pGCA_002214785_00039 - 0.81 9.1 5.0 0.46 10.0 1.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein THOC7 PF05615.13 pGCA_002214785_00039 - 3 8.1 11.6 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 pGCA_002214785_00039 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pGCA_002214785_00040 - 2.8e-30 105.7 31.4 2.8e-30 105.7 31.4 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_002214785_00040 - 0.16 11.8 1.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_002214785_00040 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pGCA_002214785_00041 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_002214785_00041 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pGCA_002214785_00042 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_002214785_00042 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_002214785_00043 - 2e-54 184.5 1.5 3.3e-54 183.8 1.5 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_002214785_00043 - 0.072 12.9 0.5 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pGCA_002214785_00044 - 3.3e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_002214785_00044 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_002214785_00045 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_002214785_00045 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002214785_00045 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_002214785_00045 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_002214785_00045 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_002214785_00045 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_002214785_00045 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_002214785_00045 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_002214785_00045 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_002214785_00045 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_002214785_00045 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_002214785_00045 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_002214785_00045 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_002214785_00045 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_002214785_00045 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_002214785_00045 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_002214785_00045 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_002214785_00045 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_002214785_00045 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_002214785_00045 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_002214785_00045 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_002214785_00045 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_002214785_00045 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_002214785_00045 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_002214785_00045 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_002214785_00045 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_002214785_00045 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_002214785_00045 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_002214785_00045 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_002214785_00045 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_002214785_00045 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pGCA_002214785_00046 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002214785_00046 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002214785_00046 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_002214785_00046 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pGCA_002214785_00047 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_002214785_00047 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_002214785_00047 - 0.08 12.7 0.3 0.22 11.3 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_002214785_00047 - 3.9 7.4 5.6 3.6 7.5 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pGCA_002214785_00048 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_002214785_00049 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_002214785_00049 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_002214785_00049 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pGCA_002214785_00051 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pGCA_002214785_00052 - 1.4e-97 327.4 8.2 1.9e-97 326.9 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_002214785_00052 - 4.7e-12 46.0 3.1 5.4e-12 45.8 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_002214785_00052 - 0.05 13.4 2.1 0.14 12.0 2.1 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_002214785_00052 - 0.05 13.9 0.7 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon EF-hand_8 PF13833.6 pGCA_002214785_00052 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pGCA_002214785_00052 - 0.34 11.1 3.3 0.78 10.0 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain PcfJ PF14284.6 pGCA_002214785_00053 - 4.7e-05 23.3 2.2 0.00012 22.0 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_002214785_00053 - 0.025 14.5 4.1 0.18 11.7 4.1 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pGCA_002214785_00055 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_002214785_00055 - 3.4e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_002214785_00055 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_002214785_00055 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_002214785_00055 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_002214785_00055 - 0.0015 18.9 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_002214785_00055 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_002214785_00055 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_002214785_00055 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pGCA_002214785_00055 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Rrp15p PF07890.12 pGCA_002214785_00057 - 0.41 11.0 7.3 0.42 10.9 7.3 1.1 1 0 0 1 1 1 0 Rrp15p Oxysterol_BP PF01237.18 pGCA_002214785_00057 - 0.82 8.4 6.8 0.84 8.4 6.8 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Asp4 PF16996.5 pGCA_002214785_00057 - 1.1 9.1 4.3 0.9 9.4 2.6 1.7 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 Casc1_N PF15927.5 pGCA_002214785_00057 - 1.8 8.2 14.1 2.1 8.0 14.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Herpes_UL56 PF04534.12 pGCA_002214785_00057 - 2.6 7.5 9.7 3.2 7.2 9.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Radial_spoke_3 PF06098.11 pGCA_002214785_00057 - 5.5 6.2 13.0 6 6.1 13.0 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 CtsR_C PF17727.1 pGCA_002214785_00060 - 0.019 15.1 0.2 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain CagX PF03524.15 pGCA_002214785_00061 - 3.9e-08 33.3 0.0 5.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Conjugal transfer protein RSV_NS2 PF03113.14 pGCA_002214785_00061 - 0.047 13.7 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 TrbH PF07283.11 pGCA_002214785_00062 - 7.2e-05 23.0 0.0 0.0001 22.5 0.0 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbH PDZ_3 PF17815.1 pGCA_002214785_00062 - 0.043 13.7 0.1 0.071 13.0 0.1 1.3 1 0 0 1 1 1 0 PDZ domain TrbI PF03743.14 pGCA_002214785_00063 - 3.7e-59 199.7 1.0 3.7e-59 199.7 1.0 2.1 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein Chordopox_A13L PF05961.11 pGCA_002214785_00063 - 0.0031 17.7 0.2 0.0094 16.2 0.2 1.8 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Shisa PF13908.6 pGCA_002214785_00063 - 0.019 15.2 2.7 0.041 14.1 2.7 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 pGCA_002214785_00063 - 0.085 13.7 0.1 0.36 11.7 0.1 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain O-antigen_lig PF13425.6 pGCA_002214785_00063 - 0.13 11.0 4.9 0.2 10.4 4.9 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Fic_N PF13784.6 pGCA_002214785_00063 - 0.16 12.1 0.9 0.31 11.1 0.9 1.4 1 0 0 1 1 1 0 Fic/DOC family N-terminal DUF4446 PF14584.6 pGCA_002214785_00063 - 0.38 10.7 4.1 0.086 12.8 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TssO PF17561.2 pGCA_002214785_00063 - 0.43 10.7 6.0 0.31 11.1 4.1 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO FlgT_N PF16548.5 pGCA_002214785_00063 - 2.3 8.8 7.7 2.3 8.8 0.3 2.5 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain SLT PF01464.20 pGCA_002214785_00064 - 2.9e-19 68.8 1.5 4.5e-19 68.2 0.9 1.5 1 1 1 2 2 2 1 Transglycosylase SLT domain TraH_2 PF06871.11 pGCA_002214785_00064 - 7.2e-10 38.9 0.0 7.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 TraH_2 SSB PF00436.25 pGCA_002214785_00066 - 1.4e-18 66.8 0.0 1.7e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MPTase-PolyVal PF18818.1 pGCA_002214785_00068 - 3.5e-43 146.7 0.7 5.5e-43 146.0 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase superfamily domain DUF1738 PF08401.11 pGCA_002214785_00068 - 4.5e-31 107.6 1.4 4.5e-31 107.6 1.4 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1738) Toprim_3 PF13362.6 pGCA_002214785_00068 - 2.3e-08 34.3 0.0 8.3e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Toprim domain DUF1816 PF08846.10 pGCA_002214785_00068 - 0.052 13.6 1.5 11 6.1 0.5 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1816) EpmC PF04315.12 pGCA_002214785_00068 - 0.31 10.7 0.0 0.31 10.7 0.0 2.7 3 0 0 3 3 3 0 Elongation factor P hydroxylase T4SS-DNA_transf PF02534.14 pGCA_002214785_00069 - 5.2e-98 328.9 0.1 7.8e-98 328.3 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002214785_00069 - 1.1e-25 90.0 0.3 2e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002214785_00069 - 5.6e-20 71.6 0.0 1.1e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 pGCA_002214785_00070 - 1.8e-08 34.5 0.1 2.3e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 pGCA_002214785_00070 - 9.7e-05 22.3 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 pGCA_002214785_00070 - 0.00041 19.9 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 pGCA_002214785_00070 - 0.00077 18.7 0.0 0.0016 17.7 0.0 1.6 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 pGCA_002214785_00070 - 0.00082 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 pGCA_002214785_00070 - 0.006 16.4 0.1 0.026 14.3 0.1 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CBP_BcsQ PF06564.12 pGCA_002214785_00070 - 0.045 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ DUF1647 PF07801.11 pGCA_002214785_00070 - 0.046 13.5 0.5 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) MipZ PF09140.11 pGCA_002214785_00070 - 0.063 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ NYN PF01936.18 pGCA_002214785_00070 - 0.088 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 NYN domain Epimerase PF01370.21 pGCA_002214785_00070 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FIST PF08495.10 pGCA_002214785_00070 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 FIST N domain DUF87 PF01935.17 pGCA_002214785_00070 - 0.18 11.9 2.7 0.87 9.6 2.7 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 pGCA_002214785_00070 - 0.2 11.7 1.7 0.39 10.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain Fic PF02661.18 pGCA_002214785_00072 - 1.1e-15 58.2 0.2 2.2e-15 57.3 0.2 1.5 1 0 0 1 1 1 1 Fic/DOC family Peptidase_S26 PF10502.9 pGCA_002214785_00073 - 1.4e-20 73.5 0.0 1.3e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 pGCA_002214785_00073 - 0.032 14.2 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase S24-like Endonuclease_NS PF01223.23 pGCA_002214785_00074 - 1.2e-29 103.7 2.6 1.3e-29 103.6 2.6 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Activator-TraM PF11657.8 pGCA_002214785_00075 - 4.8e-05 23.2 4.1 0.00012 22.0 4.2 1.6 1 1 0 1 1 1 1 Transcriptional activator TraM EssA PF10661.9 pGCA_002214785_00075 - 0.0043 16.9 3.6 0.0043 16.9 3.6 1.3 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein EssA DUF2951 PF11166.8 pGCA_002214785_00075 - 0.0078 16.4 3.7 0.0085 16.3 2.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2951) DUF2207 PF09972.9 pGCA_002214785_00075 - 0.015 14.1 2.1 0.018 13.8 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ETRAMP PF09716.10 pGCA_002214785_00075 - 0.29 11.2 3.5 0.43 10.7 3.5 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) AAA_31 PF13614.6 pGCA_002214785_00076 - 4e-23 82.2 2.7 3.3e-15 56.4 0.1 2.6 2 1 1 3 3 3 2 AAA domain CbiA PF01656.23 pGCA_002214785_00076 - 9e-17 61.3 0.2 1.3e-16 60.8 0.2 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 pGCA_002214785_00076 - 5.4e-13 48.8 0.5 1.9e-06 27.4 0.0 2.8 1 1 2 3 3 3 2 ATPase MipZ VirC1 PF07015.11 pGCA_002214785_00076 - 4.2e-10 39.3 0.1 7.8e-10 38.4 0.1 1.5 1 1 0 1 1 1 1 VirC1 protein ArsA_ATPase PF02374.15 pGCA_002214785_00076 - 8.7e-08 31.7 0.7 1.3e-07 31.1 0.7 1.6 1 1 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 pGCA_002214785_00076 - 2.7e-06 27.0 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 pGCA_002214785_00076 - 7.3e-06 25.6 0.2 2.7e-05 23.8 0.0 1.9 1 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 pGCA_002214785_00076 - 1.3e-05 24.9 0.1 3.7e-05 23.5 0.0 1.9 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 pGCA_002214785_00076 - 6.3e-05 22.6 0.0 0.00061 19.3 0.0 2.1 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 pGCA_002214785_00076 - 0.0012 18.7 0.1 0.003 17.4 0.1 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MobB PF03205.14 pGCA_002214785_00076 - 0.0018 18.2 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 pGCA_002214785_00076 - 0.008 15.9 0.2 0.25 11.0 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_24 PF13479.6 pGCA_002214785_00076 - 0.013 15.2 0.2 0.028 14.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 pGCA_002214785_00076 - 0.015 15.4 0.4 0.057 13.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 pGCA_002214785_00076 - 0.02 15.4 1.0 0.11 13.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 pGCA_002214785_00076 - 0.026 13.8 0.1 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 pGCA_002214785_00076 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 pGCA_002214785_00076 - 0.066 13.1 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF87 PF01935.17 pGCA_002214785_00076 - 0.082 13.0 1.4 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 pGCA_002214785_00076 - 0.083 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 pGCA_002214785_00076 - 0.16 10.9 0.1 0.66 8.9 0.1 2.0 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RHH_7 PF16777.5 pGCA_002214785_00077 - 0.0056 17.0 0.8 0.0066 16.8 0.8 1.2 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG Acetyltransf_7 PF13508.7 pGCA_002214785_00079 - 6.9e-10 39.2 0.2 1.2e-09 38.4 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pGCA_002214785_00079 - 7.7e-10 38.8 0.5 1.3e-09 38.1 0.5 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_002214785_00079 - 1e-09 38.7 0.1 1.3e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 pGCA_002214785_00079 - 2.5e-05 24.1 0.0 6.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 pGCA_002214785_00079 - 0.0026 17.9 2.0 0.0054 16.9 2.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pGCA_002214785_00079 - 0.0068 17.1 0.0 0.0085 16.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 pGCA_002214785_00079 - 0.99 8.8 15.5 6.9 6.1 15.5 2.3 1 1 0 1 1 1 0 Putative acetyl-transferase Relaxase PF03432.14 pGCA_002214785_00081 - 7.4e-37 127.3 19.2 7.4e-37 127.3 19.2 4.6 3 1 1 4 4 4 1 Relaxase/Mobilisation nuclease domain LPD7 PF18821.1 pGCA_002214785_00081 - 6.3e-12 45.5 0.0 2.8e-11 43.4 0.0 2.1 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 7 DUF3452 PF11934.8 pGCA_002214785_00083 - 0.013 15.0 3.8 0.016 14.8 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) PIN PF01850.21 pGCA_002214785_00087 - 8.4e-16 58.6 0.1 1e-15 58.3 0.1 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 pGCA_002214785_00087 - 0.00016 22.4 0.0 0.00019 22.2 0.0 1.3 1 1 0 1 1 1 1 PIN domain PIN_12 PF16289.5 pGCA_002214785_00087 - 0.00093 19.7 4.4 0.00093 19.7 4.4 1.4 1 1 0 1 1 1 1 PIN domain DHHA2 PF02833.14 pGCA_002214785_00087 - 0.17 12.0 0.0 0.57 10.4 0.0 1.7 1 1 1 2 2 2 0 DHHA2 domain T2SSE PF00437.20 pGCA_002214785_00088 - 4.3e-76 255.6 0.2 5.4e-76 255.2 0.2 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 pGCA_002214785_00088 - 2.2e-05 23.9 0.0 9.9e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.29 pGCA_002214785_00088 - 4.3e-05 23.4 0.0 7.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 pGCA_002214785_00088 - 0.00015 20.8 0.3 0.0004 19.4 0.1 1.7 1 1 1 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ABC_ATPase PF09818.9 pGCA_002214785_00088 - 0.00025 20.0 0.1 0.00038 19.4 0.1 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class ResIII PF04851.15 pGCA_002214785_00088 - 0.00042 20.4 0.0 0.00062 19.8 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF87 PF01935.17 pGCA_002214785_00088 - 0.00069 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain IstB_IS21 PF01695.17 pGCA_002214785_00088 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.6 pGCA_002214785_00088 - 0.00091 19.6 0.3 0.0023 18.3 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 pGCA_002214785_00088 - 0.0034 16.9 0.1 0.0087 15.6 0.1 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 pGCA_002214785_00088 - 0.0041 16.5 0.0 0.0086 15.5 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.6 pGCA_002214785_00088 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 pGCA_002214785_00088 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 pGCA_002214785_00088 - 0.021 15.4 0.4 0.073 13.6 0.3 1.7 2 1 0 2 2 1 0 ABC transporter Sigma54_activat PF00158.26 pGCA_002214785_00088 - 0.029 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 pGCA_002214785_00088 - 0.029 14.1 1.6 0.032 14.0 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 pGCA_002214785_00088 - 0.03 13.6 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 pGCA_002214785_00088 - 0.03 13.8 0.0 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.23 pGCA_002214785_00088 - 0.033 14.3 0.3 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 pGCA_002214785_00088 - 0.033 14.1 0.5 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 pGCA_002214785_00088 - 0.034 13.9 0.1 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 pGCA_002214785_00088 - 0.035 14.1 0.1 0.097 12.7 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 pGCA_002214785_00088 - 0.04 14.3 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 pGCA_002214785_00088 - 0.044 14.2 0.0 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 pGCA_002214785_00088 - 0.047 12.9 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ATP_bind_1 PF03029.17 pGCA_002214785_00088 - 0.056 13.2 0.3 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 pGCA_002214785_00088 - 0.1 12.1 0.8 0.59 9.6 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 pGCA_002214785_00088 - 0.13 11.7 0.2 0.13 11.7 0.2 2.2 2 1 1 3 3 3 0 Poxvirus A32 protein AAA_22 PF13401.6 pGCA_002214785_00088 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 pGCA_002214785_00088 - 0.13 11.7 0.5 0.19 11.2 0.4 1.5 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 pGCA_002214785_00088 - 0.56 10.7 5.0 0.38 11.2 2.6 2.1 1 1 1 2 2 2 0 AAA domain TrbC PF04956.13 pGCA_002214785_00089 - 3.5e-18 65.6 9.3 3.9e-18 65.5 9.3 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family E1-E2_ATPase PF00122.20 pGCA_002214785_00089 - 0.046 13.3 1.0 0.052 13.1 1.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Clavanin PF05452.11 pGCA_002214785_00089 - 0.3 11.3 2.5 5.1 7.4 0.1 2.2 2 0 0 2 2 2 0 Clavanin VirB3 PF05101.13 pGCA_002214785_00090 - 3.4e-16 59.2 0.5 3.8e-16 59.1 0.5 1.0 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein CytB6-F_Fe-S PF08802.10 pGCA_002214785_00090 - 0.13 12.3 0.7 0.24 11.5 0.7 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit CagE_TrbE_VirB PF03135.14 pGCA_002214785_00091 - 3.4e-35 122.0 0.0 8e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system AAA_22 PF13401.6 pGCA_002214785_00091 - 2.5e-06 27.8 0.1 0.0005 20.3 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 pGCA_002214785_00091 - 0.00044 19.9 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 pGCA_002214785_00091 - 0.00067 20.2 3.1 0.0053 17.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 pGCA_002214785_00091 - 0.00087 19.7 0.1 2.3 8.6 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 pGCA_002214785_00091 - 0.0014 17.7 0.1 0.79 8.6 0.0 3.0 2 1 1 3 3 3 2 AAA-like domain NACHT PF05729.12 pGCA_002214785_00091 - 0.0042 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 pGCA_002214785_00091 - 0.0056 17.2 0.6 0.029 14.9 0.0 2.6 3 1 0 3 3 2 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002214785_00091 - 0.006 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_30 PF13604.6 pGCA_002214785_00091 - 0.0087 15.8 0.0 0.066 12.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 pGCA_002214785_00091 - 0.011 16.1 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 pGCA_002214785_00091 - 0.02 14.7 4.5 0.13 12.1 1.3 2.8 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 pGCA_002214785_00091 - 0.037 13.8 0.0 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 pGCA_002214785_00091 - 0.053 13.4 1.1 0.46 10.4 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 pGCA_002214785_00091 - 0.057 12.6 0.0 1.3 8.2 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) FliG_N PF14842.6 pGCA_002214785_00091 - 0.061 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 FliG N-terminal domain AAA_24 PF13479.6 pGCA_002214785_00091 - 0.11 12.2 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 pGCA_002214785_00091 - 0.12 12.2 0.1 0.65 9.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 pGCA_002214785_00091 - 0.13 11.7 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 pGCA_002214785_00091 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 pGCA_002214785_00091 - 0.16 12.2 0.1 0.48 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 pGCA_002214785_00091 - 0.16 11.1 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 pGCA_002214785_00091 - 0.16 11.5 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 pGCA_002214785_00091 - 0.17 12.5 0.3 1.7 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 pGCA_002214785_00091 - 0.32 11.1 3.5 0.49 10.4 0.0 3.1 4 1 0 4 4 4 0 Helicase HerA, central domain Phage_pRha PF09669.10 pGCA_002214785_00093 - 1.2e-15 57.8 0.2 1.6e-15 57.4 0.2 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Neprosin PF03080.15 pGCA_002214785_00093 - 0.06 12.7 0.2 0.13 11.6 0.0 1.4 1 1 1 2 2 2 0 Neprosin MelC1 PF06236.11 pGCA_002214785_00093 - 0.22 11.6 0.0 0.3 11.2 0.0 1.3 1 1 0 1 1 1 0 Tyrosinase co-factor MelC1 Bro-N PF02498.17 pGCA_002214785_00094 - 8.1e-25 87.3 0.4 1.7e-24 86.3 0.1 1.7 2 0 0 2 2 2 1 BRO family, N-terminal domain TrbM PF07424.11 pGCA_002214785_00095 - 4.9e-43 146.8 0.4 4.9e-43 146.8 0.4 1.7 2 0 0 2 2 2 1 TrbM Phage_pRha PF09669.10 pGCA_002214785_00096 - 5.1e-29 100.7 0.7 1.4e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 Phage regulatory protein Rha (Phage_pRha) GN3L_Grn1 PF08701.11 pGCA_002214785_00096 - 0.078 13.1 3.3 0.14 12.3 3.3 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase T4SS PF07996.11 pGCA_002214785_00097 - 0.00012 22.6 10.7 0.0003 21.3 10.7 1.6 1 1 0 1 1 1 1 Type IV secretion system proteins Snf7 PF03357.21 pGCA_002214785_00097 - 0.006 16.2 1.9 0.0068 16.0 1.9 1.2 1 0 0 1 1 1 1 Snf7 Pepsin-I3 PF06394.13 pGCA_002214785_00097 - 0.008 16.3 0.1 0.014 15.6 0.1 1.5 1 1 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain YppG PF14179.6 pGCA_002214785_00097 - 0.011 16.5 2.6 0.015 16.0 2.6 1.2 1 0 0 1 1 1 0 YppG-like protein Laminin_II PF06009.12 pGCA_002214785_00097 - 0.041 13.9 0.8 6.5 6.8 0.6 2.1 2 0 0 2 2 2 0 Laminin Domain II PhoU_div PF01865.16 pGCA_002214785_00097 - 0.072 12.4 0.1 0.079 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 DUF948 PF06103.11 pGCA_002214785_00097 - 0.16 12.3 1.5 1 9.7 1.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HU-CCDC81_bac_2 PF18175.1 pGCA_002214785_00097 - 0.17 11.8 2.9 0.66 9.9 2.1 2.2 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 CENP-X PF09415.10 pGCA_002214785_00099 - 0.13 12.6 0.6 0.17 12.2 0.6 1.1 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TrbL PF04610.14 pGCA_002214785_00100 - 5.4e-12 45.9 27.2 5.4e-12 45.9 27.2 1.7 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Antimicrobial_2 PF08023.12 pGCA_002214785_00100 - 1.1 9.8 0.0 1.1 9.8 0.0 3.2 3 0 0 3 3 3 0 Frog antimicrobial peptide CLLAC PF15675.5 pGCA_002214785_00101 - 0.046 13.3 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain W2 PF02020.18 pGCA_002234455_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_002234455_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pGCA_002234455_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_002234455_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pGCA_002234455_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pGCA_002234455_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_002234455_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_002234455_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_002234455_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_002234455_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_002234455_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_002234455_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pGCA_002234455_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_002234455_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_002234455_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_002234455_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_002234455_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_002234455_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_002234455_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_002234455_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_002234455_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_002234455_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_002234455_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_002234455_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pGCA_002234455_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pGCA_002234455_00009 - 1.6e-16 60.0 0.9 4.1e-16 58.6 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_002234455_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_002234455_00009 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_002234455_00009 - 7.8e-06 25.8 1.5 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_002234455_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pGCA_002234455_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_002234455_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pGCA_002234455_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_002234455_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_002234455_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pGCA_002234455_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pGCA_002234455_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pGCA_002234455_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE ESP PF16590.5 pGCA_002234455_00013 - 0.55 10.5 4.6 0.27 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pGCA_002234455_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pGCA_002234455_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_002234455_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_002234455_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_002234455_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_002234455_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pGCA_002234455_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pGCA_002234455_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pGCA_002234455_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pGCA_002234455_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pGCA_002234455_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pGCA_002234455_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pGCA_002234455_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pGCA_002234455_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pGCA_002234455_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_002234455_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_002234455_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_002234455_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pGCA_002234455_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pGCA_002234455_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pGCA_002234455_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pGCA_002234455_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pGCA_002234455_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_002234455_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_002234455_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pGCA_002234455_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pGCA_002234455_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pGCA_002234455_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pGCA_002234455_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_002234455_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_002234455_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_002234455_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pGCA_002234455_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pGCA_002234455_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pGCA_002234455_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pGCA_002234455_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pGCA_002234455_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pGCA_002234455_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pGCA_002234455_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pGCA_002234455_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pGCA_002234455_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_002234455_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_002234455_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pGCA_002234455_00033 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_002234455_00033 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pGCA_002234455_00033 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pGCA_002234455_00033 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pGCA_002234455_00033 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pGCA_002234455_00033 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pGCA_002234455_00033 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pGCA_002234455_00033 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pGCA_002234455_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_002234455_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pGCA_002234455_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pGCA_002234455_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pGCA_002234455_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pGCA_002234455_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_002234455_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_002234455_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pGCA_002234455_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pGCA_002234455_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_002234455_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_002234455_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_002234455_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002234455_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_002234455_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_002234455_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_002234455_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_002234455_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pGCA_002234455_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_002234455_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_002234455_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_002234455_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_002234455_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pGCA_002234455_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pGCA_002234455_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pGCA_002234455_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pGCA_002234455_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pGCA_002234455_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pGCA_002234455_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pGCA_002234455_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pGCA_002234455_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pGCA_002234455_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pGCA_002234455_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_002234455_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_002234455_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_002234455_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pGCA_002234455_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pGCA_002234455_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pGCA_002234455_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pGCA_002234455_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_002234455_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_002234455_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pGCA_002234455_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002234455_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002234455_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pGCA_002234455_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pGCA_002234455_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pGCA_002234455_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pGCA_002234455_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pGCA_002234455_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pGCA_002234455_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_002234455_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pGCA_002234455_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pGCA_002234455_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pGCA_002234455_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pGCA_002234455_00046 - 5.7e-97 325.3 8.0 8e-97 324.8 8.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_002234455_00046 - 5.5e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_002234455_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_002234455_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_002234455_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_002234455_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_002234455_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_002234455_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_002234455_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_002234455_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_002234455_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_002234455_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_002234455_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_002234455_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_002234455_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_002234455_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_002234455_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pGCA_002234455_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_002234455_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pGCA_002234455_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_002234455_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_002234455_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_002234455_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_002234455_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_002234455_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_002234455_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_002234455_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_002234455_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pGCA_002234455_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pGCA_002234455_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pGCA_002407125_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_002407125_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pGCA_002407125_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_002407125_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pGCA_002407125_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pGCA_002407125_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_002407125_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_002407125_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_002407125_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_002407125_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_002407125_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_002407125_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pGCA_002407125_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_002407125_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_002407125_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_002407125_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_002407125_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pGCA_002407125_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_002407125_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pGCA_002407125_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_002407125_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_002407125_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_002407125_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_002407125_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pGCA_002407125_00008 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pGCA_002407125_00008 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 pGCA_002407125_00009 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_002407125_00009 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_002407125_00009 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_002407125_00009 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_002407125_00009 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pGCA_002407125_00010 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pGCA_002407125_00010 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pGCA_002407125_00010 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pGCA_002407125_00011 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_002407125_00011 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pGCA_002407125_00011 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 pGCA_002407125_00011 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 pGCA_002407125_00011 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 pGCA_002407125_00011 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 pGCA_002407125_00012 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 pGCA_002407125_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pGCA_002407125_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_002407125_00014 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pGCA_002407125_00014 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pGCA_002407125_00014 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pGCA_002407125_00014 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE TcdA_TcdB PF12919.7 pGCA_002407125_00015 - 0.00084 18.7 3.1 0.00093 18.6 3.1 1.0 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Bcl-2 PF00452.19 pGCA_002407125_00015 - 0.16 12.6 0.3 0.77 10.5 0.1 1.8 1 1 1 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family ESP PF16590.5 pGCA_002407125_00015 - 0.55 10.5 4.8 0.27 11.5 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 pGCA_002407125_00015 - 6.5 6.9 13.7 0.42 10.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function Toprim_3 PF13362.6 pGCA_002407125_00018 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_002407125_00018 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_002407125_00018 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_002407125_00018 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pGCA_002407125_00019 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pGCA_002407125_00019 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 pGCA_002407125_00020 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pGCA_002407125_00020 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pGCA_002407125_00020 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pGCA_002407125_00022 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pGCA_002407125_00023 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pGCA_002407125_00024 - 1.1e-14 54.5 0.0 2.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_002407125_00024 - 0.00029 20.3 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_002407125_00024 - 0.0018 18.0 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pGCA_002407125_00024 - 0.0084 15.5 0.0 0.053 12.9 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pGCA_002407125_00024 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pGCA_002407125_00024 - 0.15 12.1 1.7 0.77 9.8 1.7 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pGCA_002407125_00024 - 0.38 10.7 3.0 4.7 7.2 0.0 3.6 3 1 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) VASP_tetra PF08776.11 pGCA_002407125_00024 - 2.7 7.6 6.7 4.7 6.9 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pGCA_002407125_00025 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_002407125_00025 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pGCA_002407125_00025 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pGCA_002407125_00026 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pGCA_002407125_00028 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_002407125_00028 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pGCA_002407125_00029 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_002407125_00029 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pGCA_002407125_00030 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pGCA_002407125_00030 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pGCA_002407125_00030 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 pGCA_002407125_00031 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pGCA_002407125_00032 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pGCA_002407125_00033 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_002407125_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_002407125_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_002407125_00033 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pGCA_002407125_00034 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_002407125_00034 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pGCA_002407125_00034 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pGCA_002407125_00034 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 pGCA_002407125_00035 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_002407125_00035 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pGCA_002407125_00035 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 pGCA_002407125_00035 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 pGCA_002407125_00036 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 pGCA_002407125_00037 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_002407125_00037 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pGCA_002407125_00038 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pGCA_002407125_00039 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_002407125_00039 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pGCA_002407125_00040 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_002407125_00040 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002407125_00040 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_002407125_00040 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_002407125_00040 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_002407125_00040 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pGCA_002407125_00040 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 pGCA_002407125_00040 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_002407125_00040 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_002407125_00040 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_002407125_00040 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_002407125_00040 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pGCA_002407125_00040 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pGCA_002407125_00040 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pGCA_002407125_00040 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pGCA_002407125_00040 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pGCA_002407125_00040 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pGCA_002407125_00040 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pGCA_002407125_00040 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pGCA_002407125_00040 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pGCA_002407125_00040 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pGCA_002407125_00040 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_002407125_00040 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_002407125_00040 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_002407125_00040 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pGCA_002407125_00040 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pGCA_002407125_00040 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pGCA_002407125_00040 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pGCA_002407125_00040 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 pGCA_002407125_00040 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_002407125_00040 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_002407125_00040 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 pGCA_002407125_00041 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 pGCA_002407125_00042 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002407125_00042 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002407125_00042 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pGCA_002407125_00042 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 pGCA_002407125_00042 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 pGCA_002407125_00043 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pGCA_002407125_00043 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pGCA_002407125_00044 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pGCA_002407125_00045 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pGCA_002407125_00045 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 pGCA_002407125_00046 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pGCA_002407125_00046 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pGCA_002407125_00046 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pGCA_002407125_00047 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pGCA_002407125_00048 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_002407125_00048 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_002407125_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_002407125_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_002407125_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_002407125_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_002407125_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_002407125_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_002407125_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_002407125_00048 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_002407125_00048 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_002407125_00048 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_002407125_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_002407125_00048 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_002407125_00048 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_002407125_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_002407125_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pGCA_002407125_00050 - 2.9e-05 24.0 2.2 2.9e-05 24.0 2.2 1.6 2 0 0 2 2 2 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_002407125_00050 - 0.0053 16.7 3.0 0.015 15.3 3.0 1.9 1 1 0 1 1 1 1 Intein splicing domain APH PF01636.23 pGCA_002407125_00052 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 pGCA_002407125_00052 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 pGCA_002407125_00052 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 pGCA_002407125_00052 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 pGCA_002407125_00052 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 pGCA_002407125_00053 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_002407125_00053 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_002407125_00053 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_002407125_00053 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_002407125_00053 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_002407125_00053 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_002407125_00053 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_002407125_00053 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_002407125_00053 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 pGCA_002407125_00055 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 pGCA_002407125_00055 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 pGCA_002407125_00055 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 pGCA_002407125_00055 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 pGCA_002407125_00055 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 pGCA_002407125_00056 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 pGCA_002407125_00057 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pGCA_002407125_00057 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pGCA_002407125_00057 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pGCA_002407125_00057 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 pGCA_002407125_00058 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 pGCA_002407125_00059 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pGCA_002407125_00059 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pGCA_002407125_00059 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pGCA_002407125_00059 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pGCA_002407125_00059 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pGCA_002407125_00059 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pGCA_002407125_00059 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pGCA_002407125_00059 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pGCA_002407125_00059 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pGCA_002407125_00059 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pGCA_002407125_00059 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pGCA_002407125_00059 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 pGCA_002407125_00059 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 pGCA_002407125_00059 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 pGCA_002407125_00059 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 pGCA_002407125_00059 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 pGCA_002407125_00059 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_002407125_00059 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pGCA_002407125_00059 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 pGCA_002407125_00059 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 pGCA_002407125_00059 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 pGCA_002407125_00059 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 pGCA_002407125_00059 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 pGCA_002407125_00059 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 pGCA_002407125_00059 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 pGCA_002407125_00059 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 pGCA_002407125_00059 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 pGCA_002407125_00059 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 pGCA_002407125_00059 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 pGCA_002407125_00059 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 pGCA_002407125_00059 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 pGCA_002407125_00059 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 pGCA_002407125_00059 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pGCA_002407125_00059 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 pGCA_002407125_00059 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 pGCA_002407125_00059 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 pGCA_002407125_00059 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 pGCA_002407125_00060 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_002407125_00060 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pGCA_002407125_00060 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pGCA_002407125_00060 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pGCA_002407125_00060 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pGCA_002407125_00060 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pGCA_002407125_00061 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pGCA_002407125_00062 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pGCA_002407125_00063 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pGCA_002407125_00063 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pGCA_002407125_00063 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pGCA_002407125_00063 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pGCA_002407125_00063 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pGCA_002407125_00063 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pGCA_002407125_00063 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pGCA_002407125_00063 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pGCA_002407125_00064 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pGCA_002407125_00064 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pGCA_002407125_00064 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 pGCA_002407125_00065 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 pGCA_002407125_00065 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 pGCA_002407125_00065 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 pGCA_002407125_00066 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 pGCA_002407125_00066 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 pGCA_002407125_00066 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Resolvase PF00239.21 pGCA_002407145_00001 - 3e-12 46.9 0.0 4.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pGCA_002407145_00001 - 0.011 15.5 0.1 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_25 PF13481.6 pGCA_002407145_00002 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pGCA_002407145_00002 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pGCA_002407145_00002 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pGCA_002407145_00002 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pGCA_002407145_00002 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pGCA_002407145_00002 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pGCA_002407145_00002 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 pGCA_002407145_00003 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pGCA_002407145_00004 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pGCA_002407145_00006 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pGCA_002407145_00006 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pGCA_002407145_00006 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 pGCA_002407145_00007 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pGCA_002407145_00007 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Toprim_3 PF13362.6 pGCA_002407145_00008 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pGCA_002407145_00008 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pGCA_002407145_00008 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pGCA_002407145_00008 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Sds3 PF08598.11 pGCA_002407145_00011 - 0.041 13.9 5.7 0.048 13.7 5.7 1.2 1 0 0 1 1 1 0 Sds3-like ESP PF16590.5 pGCA_002407145_00011 - 0.48 10.7 5.3 0.26 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 pGCA_002407145_00011 - 4.2 7.5 13.8 0.42 10.7 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function HTH_46 PF15977.5 pGCA_002407145_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pGCA_002407145_00012 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pGCA_002407145_00012 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pGCA_002407145_00012 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pGCA_002407145_00012 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pGCA_002407145_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF3913 PF13052.6 pGCA_002407145_00014 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Acetyltransf_7 PF13508.7 pGCA_002407145_00015 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pGCA_002407145_00015 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pGCA_002407145_00015 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 pGCA_002407145_00015 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 pGCA_002407145_00015 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 pGCA_002407145_00015 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 NYN PF01936.18 pGCA_002407145_00016 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pGCA_002407145_00016 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pGCA_002407145_00016 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) SNF2_N PF00176.23 pGCA_002407145_00017 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pGCA_002407145_00017 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pGCA_002407145_00017 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pGCA_002407145_00017 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pGCA_002407145_00017 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pGCA_002407145_00018 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pGCA_002407145_00018 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 pGCA_002407145_00019 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pGCA_002407145_00019 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pGCA_002407145_00019 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pGCA_002407145_00019 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pGCA_002407145_00019 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pGCA_002407145_00020 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pGCA_002407145_00020 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4044 PF13253.6 pGCA_002407145_00021 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pGCA_002407145_00021 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pGCA_002407145_00021 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pGCA_002407145_00021 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pGCA_002407145_00021 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) LysE PF01810.18 pGCA_002407145_00022 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pGCA_002407145_00022 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pGCA_002407145_00022 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pGCA_002407145_00022 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pGCA_002407145_00022 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pGCA_002407145_00022 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pGCA_002407145_00022 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 pGCA_002407145_00023 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain Lip_prot_lig_C PF10437.9 pGCA_002407145_00024 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pGCA_002407145_00024 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain W2 PF02020.18 pGCA_002407145_00025 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pGCA_002407145_00025 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Sigma70_r4_2 PF08281.12 pGCA_002407145_00026 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 pGCA_002407145_00026 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 pGCA_002407145_00026 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain zf-HC2 PF13490.6 pGCA_002407145_00027 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 pGCA_002407145_00027 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 pGCA_002407145_00027 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain APH PF01636.23 pGCA_002407145_00028 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pGCA_002407145_00028 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pGCA_002407145_00028 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Acetyltransf_1 PF00583.25 pGCA_002407145_00029 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pGCA_002407145_00029 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pGCA_002407145_00029 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pGCA_002407145_00029 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pGCA_002407145_00029 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pGCA_002407145_00029 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pGCA_002407145_00029 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pGCA_002407145_00029 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Adenyl_transf PF04439.12 pGCA_002407145_00030 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Peptidase_C15 PF01470.17 pGCA_002407145_00031 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase APH PF01636.23 pGCA_002407145_00032 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pGCA_002407145_00032 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pGCA_002407145_00032 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pGCA_002407145_00032 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pGCA_002407145_00032 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pGCA_002407145_00032 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase AAA_18 PF13238.6 pGCA_002407145_00033 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pGCA_002407145_00033 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pGCA_002407145_00033 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pGCA_002407145_00033 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pGCA_002407145_00033 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pGCA_002407145_00033 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pGCA_002407145_00033 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pGCA_002407145_00033 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pGCA_002407145_00033 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pGCA_002407145_00033 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pGCA_002407145_00033 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pGCA_002407145_00033 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 pGCA_002407145_00033 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 pGCA_002407145_00033 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 pGCA_002407145_00033 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 pGCA_002407145_00033 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 pGCA_002407145_00033 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pGCA_002407145_00033 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pGCA_002407145_00033 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 pGCA_002407145_00033 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 pGCA_002407145_00033 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 pGCA_002407145_00033 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 pGCA_002407145_00033 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 pGCA_002407145_00033 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 pGCA_002407145_00033 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 pGCA_002407145_00033 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 pGCA_002407145_00033 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 pGCA_002407145_00033 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 pGCA_002407145_00033 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 pGCA_002407145_00033 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 pGCA_002407145_00033 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 pGCA_002407145_00033 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 pGCA_002407145_00033 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pGCA_002407145_00033 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 pGCA_002407145_00033 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 pGCA_002407145_00033 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 pGCA_002407145_00033 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family DUF4111 PF13427.6 pGCA_002407145_00034 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) DUF4111 PF13427.6 pGCA_002407145_00035 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pGCA_002407145_00035 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pGCA_002407145_00035 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pGCA_002407145_00035 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain PNP_UDP_1 PF01048.20 pGCA_002407145_00036 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily CPSF_A PF03178.15 pGCA_002407145_00037 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 pGCA_002407145_00037 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 pGCA_002407145_00037 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 pGCA_002407145_00037 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 pGCA_002407145_00037 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) GTP_EFTU PF00009.27 pGCA_002407145_00039 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pGCA_002407145_00039 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pGCA_002407145_00039 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pGCA_002407145_00039 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pGCA_002407145_00039 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pGCA_002407145_00039 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pGCA_002407145_00039 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pGCA_002407145_00039 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pGCA_002407145_00039 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 pGCA_002407145_00040 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 pGCA_002407145_00040 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 pGCA_002407145_00040 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 pGCA_002407145_00040 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 pGCA_002407145_00040 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase PcfJ PF14284.6 pGCA_002407145_00042 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pGCA_002407145_00042 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Topoisom_bac PF01131.20 pGCA_002407145_00043 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pGCA_002407145_00043 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pGCA_002407145_00043 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pGCA_002407145_00043 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pGCA_002407145_00043 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pGCA_002407145_00043 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pGCA_002407145_00043 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pGCA_002407145_00043 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pGCA_002407145_00043 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pGCA_002407145_00043 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pGCA_002407145_00043 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pGCA_002407145_00043 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pGCA_002407145_00043 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pGCA_002407145_00043 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pGCA_002407145_00043 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pGCA_002407145_00043 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pGCA_002407145_00043 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1461 PF07314.11 pGCA_002407145_00044 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CdhD PF03599.16 pGCA_002407145_00045 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pGCA_002407145_00045 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pGCA_002407145_00045 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pGCA_002407145_00046 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pGCA_002407145_00046 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TrbM PF07424.11 pGCA_002407145_00047 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pGCA_002407145_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pGCA_002407145_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) T4SS-DNA_transf PF02534.14 pGCA_002407145_00049 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002407145_00049 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002407145_00049 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pGCA_002407145_00049 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 pGCA_002407145_00049 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Carbam_trans_N PF02543.15 pGCA_002407145_00050 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T2SSE PF00437.20 pGCA_002407145_00051 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pGCA_002407145_00051 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002407145_00051 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pGCA_002407145_00051 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pGCA_002407145_00051 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pGCA_002407145_00051 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pGCA_002407145_00051 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 pGCA_002407145_00051 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pGCA_002407145_00051 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pGCA_002407145_00051 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pGCA_002407145_00051 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pGCA_002407145_00051 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pGCA_002407145_00051 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pGCA_002407145_00051 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pGCA_002407145_00051 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pGCA_002407145_00051 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pGCA_002407145_00051 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pGCA_002407145_00051 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pGCA_002407145_00051 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pGCA_002407145_00051 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pGCA_002407145_00051 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pGCA_002407145_00051 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pGCA_002407145_00051 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pGCA_002407145_00051 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pGCA_002407145_00051 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pGCA_002407145_00051 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pGCA_002407145_00051 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pGCA_002407145_00051 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pGCA_002407145_00051 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 pGCA_002407145_00051 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pGCA_002407145_00051 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pGCA_002407145_00051 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pGCA_002407145_00052 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pGCA_002407145_00052 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pGCA_002407145_00053 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein VirB8 PF04335.13 pGCA_002407145_00054 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pGCA_002407145_00054 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C La_HTH_kDCL PF18177.1 pGCA_002407145_00055 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain TrbL PF04610.14 pGCA_002407145_00056 - 2.8e-30 105.7 32.6 2.8e-30 105.7 32.6 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pGCA_002407145_00056 - 0.072 12.9 0.7 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pGCA_002407145_00056 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 pGCA_002407145_00056 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pGCA_002407145_00057 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pGCA_002407145_00057 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pGCA_002407145_00057 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pGCA_002407145_00057 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IF2_N PF04760.15 pGCA_002407145_00058 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pGCA_002407145_00058 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pGCA_002407145_00058 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pGCA_002407145_00058 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pGCA_002407145_00059 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PBECR2 PF18810.1 pGCA_002407145_00060 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Phage_pRha PF09669.10 pGCA_002407145_00061 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pGCA_002407145_00061 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pGCA_002407145_00061 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CagE_TrbE_VirB PF03135.14 pGCA_002407145_00062 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pGCA_002407145_00062 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrbC PF04956.13 pGCA_002407145_00063 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pGCA_002407145_00063 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pGCA_002407145_00065 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Activator-TraM PF11657.8 pGCA_002407145_00066 - 1.8e-05 24.6 4.4 2.6e-05 24.1 4.4 1.2 1 0 0 1 1 1 1 Transcriptional activator TraM Use1 PF09753.9 pGCA_002407145_00066 - 0.0028 17.4 0.6 0.0038 17.0 0.6 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4199 PF13858.6 pGCA_002407145_00066 - 0.0044 17.5 1.3 0.0057 17.1 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) EMP24_GP25L PF01105.24 pGCA_002407145_00066 - 0.011 15.7 0.6 0.012 15.6 0.6 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ETRAMP PF09716.10 pGCA_002407145_00066 - 0.017 15.2 5.0 0.017 15.1 4.2 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Arc_PepC_II PF06847.11 pGCA_002407145_00066 - 0.025 15.1 2.2 0.039 14.5 0.9 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DUF2207 PF09972.9 pGCA_002407145_00066 - 0.027 13.3 3.2 0.029 13.1 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2951 PF11166.8 pGCA_002407145_00066 - 0.078 13.2 6.3 0.074 13.3 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) AAA_31 PF13614.6 pGCA_002407145_00067 - 2.4e-23 83.0 2.4 2.2e-15 57.0 0.1 2.6 2 1 1 3 3 3 2 AAA domain CbiA PF01656.23 pGCA_002407145_00067 - 6.5e-17 61.8 0.2 9.2e-17 61.3 0.2 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 pGCA_002407145_00067 - 7e-13 48.5 0.3 1.4e-09 37.6 0.2 2.9 1 1 1 2 2 2 1 ATPase MipZ VirC1 PF07015.11 pGCA_002407145_00067 - 1.2e-10 41.1 0.1 2.2e-10 40.2 0.1 1.5 1 1 0 1 1 1 1 VirC1 protein ArsA_ATPase PF02374.15 pGCA_002407145_00067 - 5e-08 32.5 0.7 8.9e-08 31.7 0.2 1.7 1 1 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 pGCA_002407145_00067 - 4.6e-06 26.3 0.0 8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 pGCA_002407145_00067 - 8.5e-06 25.4 0.2 2.8e-05 23.7 0.0 1.9 1 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 pGCA_002407145_00067 - 1.5e-05 24.7 0.1 4e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 pGCA_002407145_00067 - 7.1e-05 22.4 0.0 0.00059 19.4 0.0 2.1 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsQ MobB PF03205.14 pGCA_002407145_00067 - 0.0012 18.7 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 pGCA_002407145_00067 - 0.0013 18.6 0.1 0.0036 17.1 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 pGCA_002407145_00067 - 0.0086 15.8 0.2 0.25 11.0 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA_24 PF13479.6 pGCA_002407145_00067 - 0.014 15.1 0.2 0.031 14.0 0.1 1.7 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 pGCA_002407145_00067 - 0.016 15.2 0.4 0.064 13.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 pGCA_002407145_00067 - 0.029 14.9 1.7 0.092 13.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 pGCA_002407145_00067 - 0.042 13.1 0.1 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 pGCA_002407145_00067 - 0.047 13.8 1.5 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 pGCA_002407145_00067 - 0.05 13.2 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 pGCA_002407145_00067 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 pGCA_002407145_00067 - 0.076 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 pGCA_002407145_00067 - 0.15 11.0 0.1 1 8.3 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 pGCA_002407145_00067 - 0.19 11.7 0.5 2.4 8.1 0.0 2.4 2 2 1 3 3 3 0 Type III restriction enzyme, res subunit RHH_7 PF16777.5 pGCA_002407145_00068 - 0.0075 16.6 0.3 0.009 16.4 0.3 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG CheX PF13690.6 pGCA_002407145_00068 - 0.023 14.9 0.1 0.025 14.7 0.1 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX ParD PF09386.10 pGCA_002407145_00068 - 0.11 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Antitoxin ParD Relaxase PF03432.14 pGCA_002407145_00070 - 2.6e-38 132.0 18.8 2.6e-38 132.0 18.8 4.1 3 1 1 4 4 4 1 Relaxase/Mobilisation nuclease domain LPD7 PF18821.1 pGCA_002407145_00070 - 8.5e-12 45.0 0.0 4.1e-11 42.9 0.0 2.2 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 7 Fucose_iso_N1 PF07881.12 pGCA_002407145_00070 - 9.9 6.0 6.5 14 5.5 0.1 3.0 3 0 0 3 3 3 0 L-fucose isomerase, first N-terminal domain DUF3452 PF11934.8 pGCA_002407145_00072 - 0.014 14.9 4.4 0.017 14.7 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) PIN PF01850.21 pGCA_002407145_00075 - 1.6e-15 57.7 0.1 2e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 pGCA_002407145_00075 - 0.00017 22.3 0.0 0.00021 22.0 0.0 1.3 1 1 0 1 1 1 1 PIN domain PIN_12 PF16289.5 pGCA_002407145_00075 - 0.0012 19.4 4.5 0.0012 19.4 4.5 1.4 1 1 0 1 1 1 1 PIN domain DHHA2 PF02833.14 pGCA_002407145_00075 - 0.03 14.5 0.0 0.073 13.3 0.0 1.7 1 1 0 1 1 1 0 DHHA2 domain T2SSE PF00437.20 pGCA_002407145_00076 - 1.6e-75 253.7 0.3 2e-75 253.3 0.3 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 pGCA_002407145_00076 - 2.8e-05 23.6 0.1 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.29 pGCA_002407145_00076 - 3e-05 23.8 0.1 5.2e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 pGCA_002407145_00076 - 0.00014 20.9 0.4 0.00036 19.6 0.1 1.7 1 1 1 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pGCA_002407145_00076 - 0.0004 20.4 0.0 0.00074 19.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 pGCA_002407145_00076 - 0.00053 20.3 0.3 0.0014 19.0 0.3 1.7 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 pGCA_002407145_00076 - 0.001 19.2 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain IstB_IS21 PF01695.17 pGCA_002407145_00076 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 pGCA_002407145_00076 - 0.0033 17.2 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 pGCA_002407145_00076 - 0.0039 16.6 0.0 0.0081 15.5 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_7 PF12775.7 pGCA_002407145_00076 - 0.0047 16.5 0.1 0.012 15.2 0.1 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region ABC_ATPase PF09818.9 pGCA_002407145_00076 - 0.011 14.6 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NACHT PF05729.12 pGCA_002407145_00076 - 0.013 15.4 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 pGCA_002407145_00076 - 0.027 14.2 1.2 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 pGCA_002407145_00076 - 0.029 14.5 0.4 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 pGCA_002407145_00076 - 0.033 13.9 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 pGCA_002407145_00076 - 0.033 14.2 0.1 0.096 12.7 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 pGCA_002407145_00076 - 0.038 13.3 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 pGCA_002407145_00076 - 0.041 14.3 0.0 0.44 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 pGCA_002407145_00076 - 0.041 13.6 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 pGCA_002407145_00076 - 0.042 13.8 0.5 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 pGCA_002407145_00076 - 0.046 14.2 0.5 0.13 12.8 0.4 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 pGCA_002407145_00076 - 0.055 12.6 0.1 0.074 12.2 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 pGCA_002407145_00076 - 0.073 13.5 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 pGCA_002407145_00076 - 0.085 12.4 0.7 0.67 9.5 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 pGCA_002407145_00076 - 0.095 12.5 0.5 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 pGCA_002407145_00076 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.12 pGCA_002407145_00076 - 0.19 11.2 0.2 0.19 11.2 0.2 2.1 2 1 1 3 3 3 0 Poxvirus A32 protein AAA_23 PF13476.6 pGCA_002407145_00076 - 0.54 10.7 4.8 0.24 11.9 1.1 2.1 2 1 0 2 2 2 0 AAA domain TrbC PF04956.13 pGCA_002407145_00077 - 1.1e-17 64.0 9.2 1.2e-17 63.9 9.2 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF3687 PF12459.8 pGCA_002407145_00077 - 0.1 12.1 0.5 0.1 12.1 0.5 1.7 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein VirB3 PF05101.13 pGCA_002407145_00078 - 1.5e-14 54.0 0.9 1.8e-14 53.7 0.9 1.0 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TraL PF07178.11 pGCA_002407145_00078 - 0.15 12.5 1.6 0.16 12.5 1.6 1.2 1 1 0 1 1 1 0 TraL protein CagE_TrbE_VirB PF03135.14 pGCA_002407145_00079 - 9.5e-34 117.3 0.0 2.1e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system AAA_22 PF13401.6 pGCA_002407145_00079 - 1e-06 29.1 0.4 0.0007 19.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 pGCA_002407145_00079 - 0.00014 22.3 0.1 2.6 8.5 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 pGCA_002407145_00079 - 0.00049 19.8 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.7 pGCA_002407145_00079 - 0.0017 17.3 0.0 0.56 9.1 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_16 PF13191.6 pGCA_002407145_00079 - 0.0027 18.1 0.1 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 pGCA_002407145_00079 - 0.0037 17.8 6.6 0.005 17.4 0.3 3.1 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 pGCA_002407145_00079 - 0.004 17.1 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 pGCA_002407145_00079 - 0.0067 16.2 0.0 0.071 12.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 pGCA_002407145_00079 - 0.0068 16.9 0.1 0.043 14.3 0.0 2.5 3 0 0 3 3 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pGCA_002407145_00079 - 0.0069 15.8 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_21 PF13304.6 pGCA_002407145_00079 - 0.0073 16.2 0.5 5.6 6.7 0.1 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 pGCA_002407145_00079 - 0.055 13.6 1.6 0.65 10.0 0.0 3.2 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_24 PF13479.6 pGCA_002407145_00079 - 0.072 12.8 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 pGCA_002407145_00079 - 0.083 12.7 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Syntaxin_2 PF14523.6 pGCA_002407145_00079 - 0.094 13.1 1.2 2.8 8.4 0.3 2.9 2 0 0 2 2 2 0 Syntaxin-like protein ATPase_2 PF01637.18 pGCA_002407145_00079 - 0.1 12.5 2.6 0.52 10.2 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 pGCA_002407145_00079 - 0.12 11.6 1.5 1.4 8.1 0.0 3.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 pGCA_002407145_00079 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 pGCA_002407145_00079 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 pGCA_002407145_00079 - 0.21 11.3 0.0 0.77 9.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain CdiA_C_tRNase PF18664.1 pGCA_002407145_00079 - 0.24 11.6 3.2 0.23 11.7 0.3 2.4 3 0 0 3 3 2 0 CdiA C-terminal tRNase domain AAA_14 PF13173.6 pGCA_002407145_00079 - 1.9 8.5 8.4 17 5.5 0.0 4.7 5 1 0 5 5 5 0 AAA domain TrbM PF07424.11 pGCA_002407145_00080 - 2.3e-43 147.8 0.8 3.3e-43 147.3 0.8 1.2 1 0 0 1 1 1 1 TrbM T4SS PF07996.11 pGCA_002407145_00081 - 7.2e-05 23.3 17.8 7.2e-05 23.3 17.8 2.3 1 1 1 2 2 2 1 Type IV secretion system proteins DUF2730 PF10805.8 pGCA_002407145_00081 - 0.064 13.4 3.0 6.8 6.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) LPP PF04728.13 pGCA_002407145_00081 - 0.24 11.8 0.0 0.24 11.8 0.0 3.9 4 1 0 4 4 4 0 Lipoprotein leucine-zipper DUF2203 PF09969.9 pGCA_002407145_00081 - 0.49 11.1 10.3 2 9.1 2.0 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 pGCA_002407145_00081 - 3 8.4 22.4 0.97 10.0 3.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 pGCA_002407145_00081 - 7.3 6.9 10.4 2.4 8.5 1.0 3.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) FeoB_Cyto PF17910.1 pGCA_002407145_00081 - 7.7 7.1 8.9 1.3 9.6 1.8 2.9 2 2 1 3 3 3 0 FeoB cytosolic helical domain Fib_alpha PF08702.10 pGCA_002407145_00081 - 9.9 6.3 26.2 2.2 8.4 5.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CENP-X PF09415.10 pGCA_002407145_00082 - 0.036 14.4 0.2 0.047 14.0 0.2 1.1 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TrbL PF04610.14 pGCA_002407145_00083 - 4.5e-13 49.5 31.2 4.5e-13 49.5 31.2 1.9 1 1 1 2 2 2 2 TrbL/VirB6 plasmid conjugal transfer protein VirB8 PF04335.13 pGCA_002407145_00084 - 9.4e-42 143.3 0.3 1.1e-41 143.1 0.3 1.0 1 0 0 1 1 1 1 VirB8 protein DNA_pack_N PF02500.15 pGCA_002407145_00084 - 0.007 16.2 0.2 0.012 15.5 0.2 1.3 1 0 0 1 1 1 1 Probable DNA packing protein, N-terminus CagX PF03524.15 pGCA_002407145_00085 - 6.9e-50 169.7 0.2 9.2e-50 169.3 0.2 1.1 1 0 0 1 1 1 1 Conjugal transfer protein TrbH PF07283.11 pGCA_002407145_00086 - 4.8e-06 26.7 0.0 7.1e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Conjugal transfer protein TrbH FeoB_N PF02421.18 pGCA_002407145_00086 - 0.091 12.3 1.0 0.13 11.8 1.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B TrbI PF03743.14 pGCA_002407145_00087 - 1.8e-60 204.0 0.7 1.8e-60 204.0 0.7 2.2 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein SARAF PF06682.12 pGCA_002407145_00087 - 0.0044 16.7 0.2 0.0073 16.0 0.2 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 pGCA_002407145_00087 - 0.028 15.3 0.1 0.1 13.5 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4330 PF14221.6 pGCA_002407145_00087 - 0.069 13.4 1.4 0.16 12.2 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4330) Shisa PF13908.6 pGCA_002407145_00087 - 0.16 12.2 1.7 0.36 11.0 1.7 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ctr PF04145.15 pGCA_002407145_00087 - 0.25 11.9 0.9 0.59 10.7 0.8 1.6 1 1 0 1 1 1 0 Ctr copper transporter family Chordopox_A13L PF05961.11 pGCA_002407145_00087 - 0.54 10.5 3.2 0.3 11.3 0.2 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein O-antigen_lig PF13425.6 pGCA_002407145_00087 - 0.55 9.0 5.2 1.2 7.9 5.2 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SLT PF01464.20 pGCA_002407145_00088 - 5.5e-18 64.7 1.2 7.8e-18 64.2 1.2 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain TraH_2 PF06871.11 pGCA_002407145_00088 - 2.1e-10 40.6 0.0 2.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 TraH_2 HU-CCDC81_euk_2 PF18289.1 pGCA_002407145_00088 - 0.028 14.6 0.4 0.062 13.5 0.3 1.6 1 1 1 2 2 2 0 CCDC81 eukaryotic HU domain 2 HP0268 PF18618.1 pGCA_002407145_00088 - 0.94 10.0 5.6 0.55 10.7 0.2 2.8 2 1 1 3 3 3 0 HP0268 SSB PF00436.25 pGCA_002407145_00090 - 2.8e-18 65.9 0.0 3.4e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MPTase-PolyVal PF18818.1 pGCA_002407145_00092 - 5.4e-43 146.0 0.0 1e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase superfamily domain DUF1738 PF08401.11 pGCA_002407145_00092 - 8.1e-32 110.0 1.4 3.4e-31 108.0 1.4 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) Toprim_3 PF13362.6 pGCA_002407145_00092 - 2.8e-08 34.0 0.0 7.1e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Toprim domain DUF29 PF01724.16 pGCA_002407145_00092 - 6.6 7.0 11.6 0.25 11.6 2.6 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF29 T4SS-DNA_transf PF02534.14 pGCA_002407145_00093 - 2.9e-97 326.4 0.1 4.2e-97 325.9 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pGCA_002407145_00093 - 4.1e-26 91.4 0.0 7.9e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pGCA_002407145_00093 - 1e-20 74.0 0.1 2.1e-19 69.7 0.1 2.0 1 1 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 pGCA_002407145_00094 - 3.2e-08 33.7 0.0 4e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 pGCA_002407145_00094 - 0.00011 22.1 0.1 0.00023 21.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 pGCA_002407145_00094 - 0.00042 19.8 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 pGCA_002407145_00094 - 0.00058 19.1 0.1 0.0017 17.6 0.0 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 pGCA_002407145_00094 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 pGCA_002407145_00094 - 0.0066 16.3 0.1 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF1647 PF07801.11 pGCA_002407145_00094 - 0.018 14.8 0.5 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Epimerase PF01370.21 pGCA_002407145_00094 - 0.02 14.3 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBP_BcsQ PF06564.12 pGCA_002407145_00094 - 0.043 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 pGCA_002407145_00094 - 0.064 12.5 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ FIST PF08495.10 pGCA_002407145_00094 - 0.099 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 FIST N domain Fic PF02661.18 pGCA_002407145_00096 - 5.2e-16 59.3 0.1 8.3e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Fic/DOC family Peptidase_S26 PF10502.9 pGCA_002407145_00097 - 1e-20 73.9 0.0 1e-19 70.7 0.0 1.9 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 pGCA_002407145_00097 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Relaxase PF03432.14 pKC907204_00001 - 2.1e-09 37.3 4.9 2.1e-09 37.3 4.9 2.9 2 1 1 3 3 3 1 Relaxase/Mobilisation nuclease domain B3 PF02362.21 pKC907204_00001 - 0.00093 19.0 0.2 0.01 15.7 0.1 2.6 2 0 0 2 2 2 1 B3 DNA binding domain Ig_GlcNase PF18368.1 pKC907204_00001 - 0.039 14.1 0.2 0.17 12.0 0.0 2.1 3 0 0 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain DUF2884 PF11101.8 pKC907204_00001 - 0.045 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Lip_prot_lig_C PF10437.9 pKX686749_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pKX686749_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pKX686749_00003 - 0.01 15.2 2.9 0.01 15.2 2.9 2.3 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 pKX686749_00003 - 0.78 8.8 4.5 0.88 8.6 4.5 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LysE PF01810.18 pKX686749_00004 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pKX686749_00004 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pKX686749_00004 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pKX686749_00004 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pKX686749_00004 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pKX686749_00004 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pKX686749_00004 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pKX686749_00004 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pKX686749_00004 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pKX686749_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pKX686749_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pKX686749_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pKX686749_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pKX686749_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pKX686749_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pKX686749_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pKX686749_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pKX686749_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pKX686749_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pKX686749_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pKX686749_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pKX686749_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pKX686749_00009 - 1.4e-16 60.2 0.7 4.2e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pKX686749_00009 - 8.6e-08 32.4 8.6 8.6e-08 32.4 8.6 4.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pKX686749_00009 - 9.2e-07 29.2 0.2 4.9e-05 23.6 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Eco57I PF07669.11 pKX686749_00009 - 2.1e-05 24.9 0.7 0.00022 21.7 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase DEAD PF00270.29 pKX686749_00009 - 2.5e-05 24.1 2.4 0.0015 18.3 0.5 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase HTH_19 PF12844.7 pKX686749_00010 - 1e-05 25.5 0.2 0.01 15.8 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pKX686749_00010 - 5.4e-05 23.2 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pKX686749_00010 - 0.0011 19.0 0.0 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pKX686749_00010 - 0.0078 15.7 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 pKX686749_00010 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 pKX686749_00010 - 0.016 15.0 0.1 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 pKX686749_00010 - 0.019 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Imm3 PF14425.6 pKX686749_00010 - 0.042 13.9 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 HTH_26 PF13443.6 pKX686749_00010 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 pKX686749_00010 - 0.097 12.9 0.0 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 pKX686749_00010 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pKX686749_00010 - 0.13 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 pKX686749_00010 - 0.14 12.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Mga PF08280.11 pKX686749_00010 - 0.15 12.1 1.8 5.6 7.1 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Relaxase PF03432.14 pKX686749_00011 - 5.1e-10 39.4 7.2 5.1e-10 39.4 7.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pKX686749_00012 - 0.00011 22.1 6.6 0.045 13.8 0.9 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pKX686749_00012 - 0.053 13.6 2.1 0.072 13.2 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pKX686749_00012 - 0.4 10.8 8.5 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pKX686749_00012 - 0.4 10.9 6.2 0.56 10.5 1.1 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pKX686749_00012 - 0.54 10.6 5.9 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain CdvA PF18822.1 pKX686749_00013 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pKX686749_00013 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pKX686749_00013 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pKX686749_00015 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pKX686749_00015 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pKX686749_00015 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pKX686749_00015 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pKX686749_00016 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pKX686749_00016 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 pKX686749_00017 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pKX686749_00017 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pKX686749_00017 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pKX686749_00019 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pKX686749_00020 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pKX686749_00021 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pKX686749_00021 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pKX686749_00021 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pKX686749_00021 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pKX686749_00021 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pKX686749_00021 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pKX686749_00021 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pKX686749_00022 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pKX686749_00022 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pKX686749_00022 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pKX686749_00023 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pKX686749_00025 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pKX686749_00025 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pKX686749_00026 - 7e-51 173.3 0.4 1.6e-50 172.1 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pKX686749_00026 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pKX686749_00027 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pKX686749_00027 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pKX686749_00027 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 pKX686749_00028 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pKX686749_00029 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pKX686749_00030 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pKX686749_00030 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pKX686749_00030 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pKX686749_00030 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pKX686749_00031 - 1.8e-28 100.3 13.3 2.5e-28 99.9 13.3 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pKX686749_00031 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pKX686749_00031 - 0.017 15.7 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pKX686749_00031 - 0.5 11.1 11.4 0.41 11.3 4.5 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 pKX686749_00032 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pKX686749_00032 - 0.065 13.0 0.9 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pKX686749_00032 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Trep_dent_lipo PF09710.10 pKX686749_00033 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pKX686749_00033 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pKX686749_00033 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pKX686749_00034 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pKX686749_00034 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pKX686749_00035 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pKX686749_00035 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 pKX686749_00035 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pKX686749_00036 - 7.4e-48 162.9 0.1 7.4e-48 162.9 0.1 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pKX686749_00036 - 0.044 12.9 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pKX686749_00037 - 7.7e-55 185.9 0.0 8.9e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pKX686749_00037 - 7.4e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pKX686749_00037 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pKX686749_00037 - 0.00028 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pKX686749_00037 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pKX686749_00037 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pKX686749_00037 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pKX686749_00037 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pKX686749_00037 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pKX686749_00037 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pKX686749_00037 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pKX686749_00037 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pKX686749_00037 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 pKX686749_00037 - 0.02 14.9 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 pKX686749_00037 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 pKX686749_00037 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 pKX686749_00037 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 pKX686749_00037 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pKX686749_00037 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 pKX686749_00037 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pKX686749_00037 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pKX686749_00037 - 0.045 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pKX686749_00037 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pKX686749_00037 - 0.065 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pKX686749_00037 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pKX686749_00037 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pKX686749_00037 - 0.1 12.6 0.5 0.25 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pKX686749_00037 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pKX686749_00037 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pKX686749_00037 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pKX686749_00037 - 0.44 11.0 4.2 0.33 11.4 1.4 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pKX686749_00038 - 8.4e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pKX686749_00038 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pKX686749_00038 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pKX686749_00038 - 0.19 11.8 0.2 0.33 11.0 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 pKX686749_00039 - 2.9e-16 59.8 0.3 3.7e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pKX686749_00039 - 0.078 12.8 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pKX686749_00040 - 3.9e-38 130.8 2.1 5e-38 130.5 2.1 1.1 1 0 0 1 1 1 1 TrbM HpaB PF03241.13 pKX686749_00040 - 0.17 10.9 0.1 1 8.4 0.0 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal PRELI PF04707.14 pKX686749_00041 - 0.024 14.4 1.8 0.032 14.0 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pKX686749_00041 - 1.7 8.4 10.4 3.2 7.5 8.6 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT20 PF14931.6 pKX686749_00041 - 3.6 7.8 9.8 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CdhD PF03599.16 pKX686749_00042 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pKX686749_00042 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pKX686749_00042 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pKX686749_00043 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pKX686749_00044 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pKX686749_00044 - 1.8e-12 47.4 0.5 9.7e-12 45.0 0.1 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pKX686749_00044 - 1.6e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pKX686749_00044 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pKX686749_00044 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pKX686749_00044 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pKX686749_00044 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pKX686749_00044 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pKX686749_00044 - 0.088 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 pKX686749_00044 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pKX686749_00044 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pKX686749_00044 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pKX686749_00044 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pKX686749_00044 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pKX686749_00044 - 6.9 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pKX686749_00044 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pKX686749_00045 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pKX686749_00045 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pKX686749_00047 - 2.9e-58 196.6 0.3 4.1e-58 196.1 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pKX686749_00047 - 2.6e-23 82.1 0.0 9.7e-23 80.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pKX686749_00047 - 1.1e-16 60.6 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pKX686749_00047 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pKX686749_00047 - 1e-06 28.8 0.1 2.4e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pKX686749_00047 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pKX686749_00047 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pKX686749_00047 - 0.021 14.1 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pKX686749_00047 - 0.045 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPT PF07931.12 pKX686749_00048 - 9.2e-06 25.6 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 pKX686749_00048 - 1.2e-05 25.9 0.0 1.6e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pKX686749_00048 - 0.019 15.1 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MKT1_N PF12247.8 pKX686749_00048 - 0.041 14.2 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication APH PF01636.23 pKX686749_00049 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pKX686749_00049 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pKX686749_00049 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pKX686749_00049 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pKX686749_00049 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pKX686749_00049 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pKX686749_00050 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pKX686749_00051 - 1.1e-35 123.2 0.1 1.3e-35 122.9 0.1 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Zeta_toxin PF06414.12 pKX686749_00051 - 3.2e-06 26.6 0.0 3.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 pKX686749_00051 - 3.4e-06 27.4 0.0 3.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 pKX686749_00051 - 1.6e-05 25.3 0.0 2.4e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pKX686749_00051 - 2.2e-05 24.7 0.0 3.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 pKX686749_00051 - 3.3e-05 24.4 0.0 3.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 pKX686749_00051 - 9.9e-05 22.5 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pKX686749_00051 - 0.00015 22.2 0.0 0.00019 21.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 pKX686749_00051 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 pKX686749_00051 - 0.0011 18.7 0.0 0.0012 18.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 pKX686749_00051 - 0.0014 19.0 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 pKX686749_00051 - 0.0015 18.6 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 pKX686749_00051 - 0.0015 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 pKX686749_00051 - 0.0015 19.1 0.0 0.0021 18.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 pKX686749_00051 - 0.002 17.8 0.2 0.0027 17.5 0.2 1.2 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 pKX686749_00051 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 pKX686749_00051 - 0.0032 17.4 0.1 0.005 16.8 0.1 1.4 1 1 0 1 1 1 1 NTPase ATPase PF06745.13 pKX686749_00051 - 0.0062 15.9 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 pKX686749_00051 - 0.0079 15.3 0.0 0.0094 15.0 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 pKX686749_00051 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 pKX686749_00051 - 0.019 15.3 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pKX686749_00051 - 0.021 14.7 0.1 0.053 13.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Hydin_ADK PF17213.3 pKX686749_00051 - 0.026 14.8 0.2 0.036 14.4 0.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Viral_helicase1 PF01443.18 pKX686749_00051 - 0.03 14.1 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 pKX686749_00051 - 0.032 14.0 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CPT PF07931.12 pKX686749_00051 - 0.032 14.1 0.0 0.047 13.5 0.0 1.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 pKX686749_00051 - 0.034 13.7 0.1 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 pKX686749_00051 - 0.035 13.3 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 pKX686749_00051 - 0.036 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 pKX686749_00051 - 0.039 13.3 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 pKX686749_00051 - 0.047 13.2 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 pKX686749_00051 - 0.048 13.6 0.0 0.051 13.5 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 pKX686749_00051 - 0.053 13.0 0.4 0.12 11.9 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 pKX686749_00051 - 0.054 13.4 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 pKX686749_00051 - 0.066 13.6 0.0 0.099 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 pKX686749_00051 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 pKX686749_00051 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP-synt_ab PF00006.25 pKX686749_00051 - 0.11 12.2 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.20 pKX686749_00051 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase IPT PF01745.16 pKX686749_00051 - 0.14 11.5 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Isopentenyl transferase AAA_3 PF07726.11 pKX686749_00051 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 pKX686749_00051 - 0.16 10.6 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 pKX686749_00051 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ArsA_ATPase PF02374.15 pKX686749_00051 - 0.17 11.0 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase cobW PF02492.19 pKX686749_00051 - 0.18 11.4 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APH PF01636.23 pKX686749_00052 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pKX686749_00052 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pKX686749_00052 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Radical_SAM PF04055.21 pKX686749_00053 - 1.3e-14 55.0 0.0 2.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 pKX686749_00053 - 4.9e-05 23.4 0.0 0.00037 20.6 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 pKX686749_00053 - 0.048 13.9 0.2 0.098 12.9 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain APH PF01636.23 pKX931102_00001 - 1.9e-24 86.9 0.0 2.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pKX931102_00001 - 0.0013 18.3 1.5 0.0013 18.3 1.5 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 pKX931103_00001 - 1.9e-24 86.9 0.0 2.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pKX931103_00001 - 0.0013 18.3 1.5 0.0013 18.3 1.5 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 pKX931104_00001 - 1.9e-24 86.9 0.0 2.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pKX931104_00001 - 0.0013 18.3 1.5 0.0013 18.3 1.5 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase LysE PF01810.18 pMLDY01000008_00001 - 5.6e-05 22.7 0.0 6.7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pMLDY01000008_00001 - 0.002 18.3 0.3 0.0021 18.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) TerC PF03741.16 pMLDY01000008_00001 - 0.041 13.6 0.3 0.047 13.4 0.3 1.0 1 0 0 1 1 1 0 Integral membrane protein TerC family DUF5305 PF17231.2 pMLDY01000008_00001 - 0.077 12.4 0.6 0.1 12.0 0.2 1.4 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Saf_2TM PF18303.1 pMLDY01000008_00001 - 0.11 12.1 0.8 0.13 11.8 0.3 1.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain PetL PF05115.14 pMLDY01000008_00001 - 3.4 7.7 9.7 4 7.5 1.2 2.5 2 1 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Flp1_like PF16982.5 pMLDY01000008_00002 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 pMLDY01000008_00002 - 0.26 10.8 3.9 0.28 10.7 3.5 1.3 1 1 0 1 1 1 0 Negative regulator of p53/TP53 YopX PF09643.10 pMLDY01000008_00004 - 1.9e-14 53.8 7.2 4.7e-13 49.3 7.2 2.2 1 1 0 1 1 1 1 YopX protein RE_ApaLI PF09499.10 pMLDY01000008_00004 - 0.0081 15.9 0.6 0.0083 15.9 0.6 1.2 1 0 0 1 1 1 1 ApaLI-like restriction endonuclease DUF2583 PF10762.9 pMLDY01000008_00006 - 0.67 10.4 3.8 15 6.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Topoisom_bac PF01131.20 pMLDY01000008_00009 - 3.9e-97 325.9 7.9 5.4e-97 325.4 7.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pMLDY01000008_00009 - 1.9e-12 47.3 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pMLDY01000008_00009 - 1.6e-08 34.1 15.1 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pMLDY01000008_00009 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pMLDY01000008_00009 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pMLDY01000008_00009 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pMLDY01000008_00009 - 0.055 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pMLDY01000008_00009 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pMLDY01000008_00009 - 0.089 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pMLDY01000008_00009 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pMLDY01000008_00009 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pMLDY01000008_00009 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pMLDY01000008_00009 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pMLDY01000008_00009 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pMLDY01000008_00009 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pMLDY01000008_00009 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pMLDY01000008_00010 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pMLDY01000008_00012 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pMLDY01000008_00012 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pMLDY01000008_00012 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pMLDY01000008_00013 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pMLDY01000008_00014 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pMLDY01000008_00014 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pMLDY01000008_00014 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pMLDY01000008_00014 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pMLDY01000008_00015 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pMLDY01000008_00015 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pMLDY01000008_00015 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pMLDY01000008_00015 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pMLDY01000008_00016 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pMLDY01000008_00016 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pMLDY01000008_00016 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pMLDY01000008_00016 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pMLDY01000008_00016 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pMLDY01000008_00016 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pMLDY01000008_00016 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pMLDY01000008_00016 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pMLDY01000008_00016 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pMLDY01000008_00016 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pMLDY01000008_00016 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pMLDY01000008_00016 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pMLDY01000008_00016 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pMLDY01000008_00016 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pMLDY01000008_00016 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pMLDY01000008_00016 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pMLDY01000008_00016 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pMLDY01000008_00016 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pMLDY01000008_00016 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pMLDY01000008_00016 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pMLDY01000008_00016 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pMLDY01000008_00016 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pMLDY01000008_00016 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pMLDY01000008_00016 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pMLDY01000008_00016 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pMLDY01000008_00016 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pMLDY01000008_00016 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pMLDY01000008_00016 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pMLDY01000008_00016 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pMLDY01000008_00016 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pMLDY01000008_00016 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pMLDY01000008_00017 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pMLDY01000008_00017 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pMLDY01000008_00018 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pMLDY01000008_00018 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pMLDY01000008_00019 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pMLDY01000008_00019 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pMLDY01000008_00020 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pMLDY01000008_00020 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pMLDY01000008_00021 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pMLDY01000008_00021 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pMLDY01000008_00021 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 T4SS PF07996.11 pMLDY01000008_00022 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pMLDY01000008_00022 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pMLDY01000008_00022 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pMLDY01000008_00022 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pMLDY01000008_00022 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pMLDY01000008_00022 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pMLDY01000008_00022 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pMLDY01000008_00022 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IF2_N PF04760.15 pMLDY01000008_00023 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pMLDY01000008_00023 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pMLDY01000008_00023 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pMLDY01000008_00023 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor SSB PF00436.25 pMLDY01000008_00024 - 1.5e-25 89.2 0.1 1.8e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 pMLDY01000008_00025 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 pMLDY01000008_00026 - 6.7e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pMLDY01000008_00026 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pMLDY01000008_00026 - 0.026 14.1 0.3 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pMLDY01000008_00026 - 0.081 12.9 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pMLDY01000008_00026 - 0.83 9.7 7.1 7.9 6.6 0.9 3.3 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pMLDY01000008_00027 - 4.1e-51 174.0 0.4 9.1e-51 172.9 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pMLDY01000008_00027 - 7.7e-21 74.1 0.9 1.4e-20 73.3 0.9 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pMLDY01000008_00027 - 2.9e-07 29.8 0.9 6.6e-07 28.6 0.9 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pMLDY01000008_00027 - 0.013 15.6 3.4 1.5 8.8 0.0 3.7 4 1 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 pMLDY01000008_00028 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pMLDY01000008_00028 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pMLDY01000008_00030 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Resolvase PF00239.21 pMLDY01000008_00031 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pMLDY01000008_00031 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pMLDY01000008_00031 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_25 PF13481.6 pMLDY01000008_00032 - 5.4e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pMLDY01000008_00032 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pMLDY01000008_00032 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pMLDY01000008_00032 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pMLDY01000008_00032 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pMLDY01000008_00032 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pMLDY01000008_00032 - 0.37 10.7 3.0 5.1 7.1 0.0 3.7 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) HicA_toxin PF07927.12 pMLDY01000008_00033 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pMLDY01000008_00034 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pMLDY01000008_00036 - 0.0052 16.8 2.6 0.0069 16.4 2.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 pMLDY01000008_00036 - 0.56 10.1 4.1 2 8.4 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) UBA_6 PF18039.1 pMLDY01000008_00037 - 0.027 14.4 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pMLDY01000008_00037 - 0.045 13.7 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pMLDY01000008_00037 - 0.068 13.6 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB DUF4223 PF13978.6 pMLDY01000008_00038 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) Toprim_3 PF13362.6 pMLDY01000008_00039 - 2.1e-08 34.4 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pMLDY01000008_00039 - 0.14 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pMLDY01000008_00039 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2004 PF09406.10 pMLDY01000008_00040 - 0.12 12.7 3.0 0.62 10.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) Sds3 PF08598.11 pMLDY01000008_00042 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pMLDY01000008_00042 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pMLDY01000008_00042 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pMLDY01000008_00043 - 0.00011 22.1 5.7 0.067 13.2 0.7 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pMLDY01000008_00043 - 0.058 13.5 1.9 0.087 12.9 1.4 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DndE PF08870.11 pMLDY01000008_00043 - 0.31 11.3 5.7 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE NLRC4_HD PF17889.1 pMLDY01000008_00043 - 0.53 10.6 5.9 2.5 8.5 2.0 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pMLDY01000008_00043 - 2 8.5 7.9 1 9.4 0.3 3.0 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Relaxase PF03432.14 pMLDY01000008_00044 - 4.3e-09 36.3 8.2 4.3e-09 36.3 8.2 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF2768 PF10966.8 pMLDY01000008_00045 - 0.053 14.0 0.6 0.11 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SNF2_N PF00176.23 pMLDY01000008_00046 - 3e-16 59.1 1.8 5.1e-16 58.3 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pMLDY01000008_00046 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pMLDY01000008_00046 - 9.6e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pMLDY01000008_00046 - 8.1e-06 25.7 2.5 0.0012 18.7 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pMLDY01000008_00046 - 2.6e-05 24.7 0.7 0.00023 21.6 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase RHH_7 PF16777.5 pMLDY01000008_00047 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pMLDY01000008_00047 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal AAA_31 PF13614.6 pMLDY01000008_00048 - 5.3e-05 23.2 0.6 0.001 19.1 0.1 2.2 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pMLDY01000008_00048 - 0.0012 18.9 0.5 0.0079 16.3 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Mur_ligase_C PF02875.21 pMLDY01000008_00048 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pMLDY01000008_00048 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pMLDY01000008_00049 - 0.00028 21.0 1.6 0.00035 20.7 1.6 1.4 1 0 0 1 1 1 1 T-antigen specific domain CEBP_ZZ PF16366.5 pMLDY01000008_00049 - 0.022 15.0 2.6 0.03 14.6 2.6 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF1272 PF06906.11 pMLDY01000008_00049 - 0.049 13.7 3.8 0.074 13.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Lip_prot_lig_C PF10437.9 pMLDZ01000009_00001 - 0.048 13.6 3.7 0.12 12.4 3.0 1.9 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus EptA_B_N PF08019.12 pMLDZ01000009_00003 - 0.12 12.3 10.8 0.053 13.4 1.6 2.3 1 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB FeoB_associated PF12669.7 pMLDZ01000009_00003 - 1.9 9.0 0.0 1.9 9.0 0.0 3.0 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein DUF2070 PF09843.9 pMLDZ01000009_00003 - 7.9 4.6 18.3 9.6 4.4 18.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Topoisom_bac PF01131.20 pMLDZ01000009_00006 - 5.8e-97 325.3 7.7 8e-97 324.8 7.7 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pMLDZ01000009_00006 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pMLDZ01000009_00006 - 1.4e-08 34.4 14.8 4.1e-06 26.5 5.0 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pMLDZ01000009_00006 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pMLDZ01000009_00006 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pMLDZ01000009_00006 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 pMLDZ01000009_00006 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pMLDZ01000009_00006 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pMLDZ01000009_00006 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pMLDZ01000009_00006 - 0.089 13.1 4.5 0.88 9.9 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain FLYWCH PF04500.16 pMLDZ01000009_00006 - 0.14 12.3 3.1 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain HTH_34 PF13601.6 pMLDZ01000009_00006 - 0.47 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pMLDZ01000009_00006 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pMLDZ01000009_00006 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pMLDZ01000009_00006 - 0.73 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pMLDZ01000009_00006 - 7 6.5 8.0 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pMLDZ01000009_00006 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 pMLDZ01000009_00007 - 0.055 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin PRELI PF04707.14 pMLDZ01000009_00008 - 0.039 13.8 0.5 0.039 13.8 0.5 1.8 2 0 0 2 2 2 0 PRELI-like family DUF2304 PF10066.9 pMLDZ01000009_00008 - 0.1 12.8 0.9 0.24 11.6 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Rsd_AlgQ PF04353.13 pMLDZ01000009_00008 - 1.3 8.9 6.1 0.44 10.5 1.9 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TrbM PF07424.11 pMLDZ01000009_00009 - 2.6e-35 121.7 1.4 3.6e-35 121.2 1.4 1.2 1 0 0 1 1 1 1 TrbM Cag12 PF13117.6 pMLDZ01000009_00010 - 5.5e-17 62.1 0.4 6.9e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pMLDZ01000009_00010 - 0.068 13.0 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pMLDZ01000009_00010 - 3.9 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) T4SS-DNA_transf PF02534.14 pMLDZ01000009_00011 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pMLDZ01000009_00011 - 9.9e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pMLDZ01000009_00011 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pMLDZ01000009_00011 - 0.046 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain T2SSE PF00437.20 pMLDZ01000009_00012 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pMLDZ01000009_00012 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pMLDZ01000009_00012 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pMLDZ01000009_00012 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pMLDZ01000009_00012 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pMLDZ01000009_00012 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pMLDZ01000009_00012 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pMLDZ01000009_00012 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pMLDZ01000009_00012 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pMLDZ01000009_00012 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pMLDZ01000009_00012 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pMLDZ01000009_00012 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pMLDZ01000009_00012 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pMLDZ01000009_00012 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pMLDZ01000009_00012 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pMLDZ01000009_00012 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pMLDZ01000009_00012 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pMLDZ01000009_00012 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pMLDZ01000009_00012 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pMLDZ01000009_00012 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pMLDZ01000009_00012 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pMLDZ01000009_00012 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pMLDZ01000009_00012 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pMLDZ01000009_00012 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pMLDZ01000009_00012 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pMLDZ01000009_00012 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pMLDZ01000009_00012 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pMLDZ01000009_00012 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pMLDZ01000009_00012 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pMLDZ01000009_00012 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pMLDZ01000009_00012 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain TrbI PF03743.14 pMLDZ01000009_00013 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pMLDZ01000009_00013 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease CagX PF03524.15 pMLDZ01000009_00014 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pMLDZ01000009_00014 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) VirB8 PF04335.13 pMLDZ01000009_00015 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pMLDZ01000009_00015 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Trep_dent_lipo PF09710.10 pMLDZ01000009_00016 - 0.035 13.0 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pMLDZ01000009_00016 - 1.5 8.6 5.2 2.6 7.9 5.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre T protein TrbL PF04610.14 pMLDZ01000009_00017 - 8.7e-31 107.4 31.2 8.7e-31 107.4 31.2 1.5 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T4SS PF07996.11 pMLDZ01000009_00018 - 2.2e-28 100.0 14.0 2.9e-28 99.6 14.0 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pMLDZ01000009_00018 - 0.0037 17.4 0.4 0.015 15.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pMLDZ01000009_00018 - 0.0089 16.7 5.2 0.0089 16.7 5.2 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pMLDZ01000009_00018 - 0.064 12.8 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pMLDZ01000009_00018 - 0.07 13.8 0.9 0.07 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain DHR10 PF18595.1 pMLDZ01000009_00018 - 5.7 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain THOC7 PF05615.13 pMLDZ01000009_00018 - 5.8 7.2 12.9 1.7 8.9 0.3 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 IF2_N PF04760.15 pMLDZ01000009_00019 - 6.5e-05 22.7 5.8 0.00049 19.9 2.0 2.2 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region HTH_16 PF12645.7 pMLDZ01000009_00019 - 0.013 15.5 1.9 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pMLDZ01000009_00019 - 0.029 15.1 0.5 2.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor FliG_N PF14842.6 pMLDZ01000009_00019 - 0.039 14.5 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain SSB PF00436.25 pMLDZ01000009_00020 - 1.4e-25 89.3 0.1 1.8e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF3895 PF13034.6 pMLDZ01000009_00021 - 0.047 13.7 0.5 0.19 11.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3895) Phage_pRha PF09669.10 pMLDZ01000009_00022 - 6.9e-29 100.3 0.0 1.1e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pMLDZ01000009_00022 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pMLDZ01000009_00022 - 0.031 13.9 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pMLDZ01000009_00022 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pMLDZ01000009_00022 - 0.56 10.3 5.4 7.7 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 CagE_TrbE_VirB PF03135.14 pMLDZ01000009_00023 - 3.6e-49 167.7 0.3 9e-49 166.4 0.3 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pMLDZ01000009_00023 - 7e-21 74.3 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein AAA_10 PF12846.7 pMLDZ01000009_00023 - 3.8e-07 29.4 0.8 9.3e-07 28.1 0.8 1.5 1 1 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 pMLDZ01000009_00023 - 0.024 14.7 4.5 1.8 8.6 0.0 3.9 4 2 1 5 5 5 0 Helicase HerA, central domain TrbC PF04956.13 pMLDZ01000009_00024 - 1.2e-15 57.5 7.6 1.4e-15 57.3 7.6 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pMLDZ01000009_00024 - 0.047 13.5 4.0 0.054 13.3 3.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CRISPR_Cas2 PF09827.9 pMLDZ01000009_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pMLDZ01000009_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Resolvase PF00239.21 pMLDZ01000009_00027 - 3.6e-33 114.7 0.7 4.5e-33 114.4 0.7 1.1 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pMLDZ01000009_00027 - 0.027 14.2 1.2 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pMLDZ01000009_00027 - 0.047 13.7 5.4 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pMLDZ01000009_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_25 PF13481.6 pMLDZ01000009_00028 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pMLDZ01000009_00028 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pMLDZ01000009_00028 - 0.0021 17.8 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pMLDZ01000009_00028 - 0.0072 15.7 0.0 0.058 12.7 0.0 2.5 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pMLDZ01000009_00028 - 0.013 15.9 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pMLDZ01000009_00028 - 0.2 11.7 2.0 0.95 9.5 2.0 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pMLDZ01000009_00028 - 0.35 10.8 3.5 5.1 7.1 0.0 3.8 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) VASP_tetra PF08776.11 pMLDZ01000009_00028 - 3.8 7.2 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain HicA_toxin PF07927.12 pMLDZ01000009_00029 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 pMLDZ01000009_00030 - 4.2e-08 33.3 0.0 4.4e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system Sdh_cyt PF01127.22 pMLDZ01000009_00032 - 0.0043 17.1 1.7 0.0054 16.8 1.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2633 PF11119.8 pMLDZ01000009_00032 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF4223 PF13978.6 pMLDZ01000009_00033 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pMLDZ01000009_00033 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain Toprim_3 PF13362.6 pMLDZ01000009_00034 - 1.6e-08 34.8 0.2 4.3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Toprim domain Retrotrans_gag PF03732.17 pMLDZ01000009_00034 - 0.017 15.4 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein Sds3 PF08598.11 pMLDZ01000009_00036 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pMLDZ01000009_00036 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pMLDZ01000009_00036 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide HTH_46 PF15977.5 pMLDZ01000009_00037 - 0.00012 22.0 7.0 0.043 13.8 1.2 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pMLDZ01000009_00037 - 0.063 13.4 2.6 0.071 13.2 1.5 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pMLDZ01000009_00037 - 0.47 10.8 6.1 1.6 9.1 2.2 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pMLDZ01000009_00037 - 0.53 10.4 9.0 1.5 8.9 0.4 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pMLDZ01000009_00037 - 0.57 10.5 7.1 0.61 10.4 1.8 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Relaxase PF03432.14 pMLDZ01000009_00038 - 7.8e-10 38.8 7.7 7.8e-10 38.8 7.7 2.5 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain YqaJ PF09588.10 pMLDZ01000009_00038 - 0.03 14.5 3.9 0.24 11.6 0.4 3.0 2 1 1 3 3 3 0 YqaJ-like viral recombinase domain HTH_19 PF12844.7 pMLDZ01000009_00039 - 6.3e-06 26.1 0.3 0.024 14.6 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 pMLDZ01000009_00039 - 7.6e-06 25.9 0.0 6.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 pMLDZ01000009_00039 - 0.00035 20.6 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 pMLDZ01000009_00039 - 0.0024 17.4 0.1 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 pMLDZ01000009_00039 - 0.0043 16.9 0.1 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_17 PF12728.7 pMLDZ01000009_00039 - 0.028 14.6 0.0 0.4 10.9 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 pMLDZ01000009_00039 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 pMLDZ01000009_00039 - 0.046 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_26 PF13443.6 pMLDZ01000009_00039 - 0.048 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_Mga PF08280.11 pMLDZ01000009_00039 - 0.049 13.7 2.0 1.7 8.7 0.1 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.6 pMLDZ01000009_00039 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 pMLDZ01000009_00039 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 pMLDZ01000009_00039 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Crp PF00325.20 pMLDZ01000009_00039 - 0.17 11.6 0.1 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family SNF2_N PF00176.23 pMLDZ01000009_00040 - 2.3e-16 59.4 3.1 2.9e-16 59.2 0.3 2.5 3 1 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pMLDZ01000009_00040 - 3.2e-08 33.8 8.8 3.2e-08 33.8 8.8 4.1 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pMLDZ01000009_00040 - 6.8e-07 29.6 1.6 2.4e-05 24.6 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 pMLDZ01000009_00040 - 9.8e-07 28.7 1.9 0.00054 19.8 0.4 3.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase BST2 PF16716.5 pMLDZ01000009_00040 - 4.3 8.0 7.3 8.1 7.1 2.7 3.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Eco57I PF07669.11 pMLDZ01000009_00041 - 1.2e-05 25.7 0.3 5e-05 23.8 0.3 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 pMLDZ01000009_00041 - 0.004 16.7 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RHH_7 PF16777.5 pMLDZ01000009_00042 - 8.5e-07 29.3 0.8 9.4e-07 29.1 0.8 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG AAA_31 PF13614.6 pMLDZ01000009_00043 - 7.8e-05 22.7 0.5 0.0011 19.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pMLDZ01000009_00043 - 0.00097 19.2 0.8 0.0077 16.3 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pMLDZ01000009_00043 - 0.014 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase ParA PF10609.9 pMLDZ01000009_00043 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Papo_T_antigen PF02380.15 pMLDZ01000009_00044 - 0.02 15.0 7.2 0.03 14.5 7.2 1.4 1 1 0 1 1 1 0 T-antigen specific domain DUF1272 PF06906.11 pMLDZ01000009_00044 - 0.059 13.5 6.2 0.095 12.8 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CEBP_ZZ PF16366.5 pMLDZ01000009_00044 - 0.14 12.4 6.2 0.19 12.0 6.2 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain LIM PF00412.22 pMLDZ01000009_00044 - 0.23 11.7 8.9 0.4 10.9 8.9 1.4 1 0 0 1 1 1 0 LIM domain DUF5595 PF18077.1 pMLDZ01000009_00044 - 0.9 9.7 5.1 0.19 11.9 1.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) LysE PF01810.18 pMLDZ01000009_00045 - 5.1e-06 26.1 0.0 5.8e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pMLDZ01000009_00045 - 0.00027 21.1 1.1 0.00031 20.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) Ac76 PF05814.11 pMLDZ01000009_00045 - 0.0043 17.0 2.2 0.0049 16.8 2.2 1.1 1 0 0 1 1 1 1 Orf76 (Ac76) Saf_2TM PF18303.1 pMLDZ01000009_00045 - 0.24 11.0 3.5 0.12 12.0 0.7 1.7 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF2873 PF11395.8 pMLDZ01000009_00045 - 3.7 7.5 6.8 0.78 9.6 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2873) LPAM_1 PF08139.12 pMLDZ01000009_00045 - 7.1 7.3 5.9 1.1 9.9 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Flp1_like PF16982.5 pMLDZ01000009_00046 - 0.044 13.2 3.1 0.044 13.2 3.1 2.1 3 0 0 3 3 3 0 Putative Flagellin, Flp1-like, domain BRI3BP PF14965.6 pMLDZ01000009_00046 - 0.053 13.0 1.6 0.06 12.9 1.6 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 GTP_EFTU PF00009.27 pMUJW01000047_00001 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pMUJW01000047_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pMUJW01000047_00001 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pMUJW01000047_00001 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pMUJW01000047_00001 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pMUJW01000047_00001 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pMUJW01000047_00001 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pMUJW01000047_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pMUJW01000047_00001 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family APH PF01636.23 pMUJW01000047_00002 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pMUJW01000047_00002 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pMUJW01000047_00002 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family W2 PF02020.18 pMUJW01000047_00003 - 0.02 15.0 0.1 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pMUJW01000047_00004 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pMUJW01000047_00004 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain LysE PF01810.18 pMUJW01000047_00005 - 0.0037 16.8 0.7 0.007 15.8 0.7 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pMUJW01000047_00005 - 0.0061 16.8 2.4 0.013 15.6 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pMUJW01000047_00005 - 0.01 15.8 2.3 0.011 15.7 1.4 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF373 PF04123.13 pMUJW01000047_00005 - 0.024 14.1 2.4 0.031 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2178 PF09946.9 pMUJW01000047_00005 - 0.039 14.1 2.1 0.059 13.5 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF5360 PF17314.2 pMUJW01000047_00005 - 0.2 11.7 3.7 0.34 11.0 0.4 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5360) DHHC PF01529.20 pMUJW01000047_00005 - 1.2 9.3 8.8 0.16 12.0 3.7 1.9 1 1 0 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pMUJW01000047_00005 - 1.4 8.5 6.0 1.7 8.2 0.3 2.4 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_A22B PF04258.13 pMUJW01000047_00005 - 2.4 7.6 9.0 42 3.5 8.9 2.0 1 1 0 1 1 1 0 Signal peptide peptidase DUF4044 PF13253.6 pMUJW01000047_00006 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pMUJW01000047_00006 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pMUJW01000047_00006 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pMUJW01000047_00006 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pMUJW01000047_00006 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pMUJW01000047_00007 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pMUJW01000047_00007 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pMUJW01000047_00008 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pMUJW01000047_00008 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pMUJW01000047_00008 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pMUJW01000047_00008 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pMUJW01000047_00008 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pMUJW01000047_00009 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pMUJW01000047_00010 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pMUJW01000047_00010 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pMUJW01000047_00010 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pMUJW01000047_00010 - 8.9e-06 25.6 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pMUJW01000047_00010 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pMUJW01000047_00011 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pMUJW01000047_00011 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pMUJW01000047_00011 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pMUJW01000047_00012 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pMUJW01000047_00012 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pMUJW01000047_00012 - 0.0083 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 pMUJW01000047_00013 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pMUJW01000047_00014 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pMUJW01000047_00014 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pMUJW01000047_00014 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pMUJW01000047_00014 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pMUJW01000047_00014 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pMUJW01000047_00015 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pMUJW01000047_00015 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pMUJW01000047_00015 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pMUJW01000047_00017 - 0.19 11.7 5.6 0.39 10.7 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pMUJW01000047_00018 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pMUJW01000047_00018 - 0.074 13.0 0.3 0.33 10.9 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pMUJW01000047_00018 - 0.13 12.7 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pMUJW01000047_00018 - 0.27 11.9 5.3 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pMUJW01000047_00019 - 0.0073 16.2 0.2 0.012 15.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) STI1 PF17830.1 pMUJW01000047_00019 - 0.13 12.2 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 STI1 domain UBA_6 PF18039.1 pMUJW01000047_00020 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pMUJW01000047_00020 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pMUJW01000047_00020 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pMUJW01000047_00020 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pMUJW01000047_00021 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pMUJW01000047_00021 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pMUJW01000047_00021 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pMUJW01000047_00023 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system AAA_25 PF13481.6 pMUJW01000047_00024 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pMUJW01000047_00024 - 0.00073 19.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pMUJW01000047_00024 - 0.0032 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pMUJW01000047_00024 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pMUJW01000047_00024 - 0.028 13.8 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pMUJW01000047_00024 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pMUJW01000047_00024 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pMUJW01000047_00025 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pMUJW01000047_00025 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pMUJW01000047_00025 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pMUJW01000047_00025 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pMUJW01000047_00026 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pMUJW01000047_00026 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pMUJW01000047_00028 - 1.4e-15 57.3 6.9 1.6e-15 57.1 6.9 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pMUJW01000047_00028 - 0.041 13.8 3.5 0.049 13.5 3.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pMUJW01000047_00029 - 2.6e-50 171.4 0.6 5.9e-50 170.2 0.6 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pMUJW01000047_00029 - 7.2e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pMUJW01000047_00029 - 0.046 13.1 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pMUJW01000047_00030 - 6.3e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2250 PF10007.9 pMUJW01000047_00030 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) PI3K_P85_iSH2 PF16454.5 pMUJW01000047_00030 - 0.045 13.3 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5512 PF17631.2 pMUJW01000047_00030 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Spore_Cse60 PF10957.8 pMUJW01000047_00030 - 0.73 9.9 5.7 7.9 6.6 0.8 3.2 2 1 1 3 3 3 0 Sporulation protein Cse60 DUF3251 PF11622.8 pMUJW01000047_00031 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pMUJW01000047_00031 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pMUJW01000047_00031 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pMUJW01000047_00031 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pMUJW01000047_00031 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pMUJW01000047_00031 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pMUJW01000047_00032 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pMUJW01000047_00033 - 0.00028 20.6 7.3 0.00048 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pMUJW01000047_00033 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pMUJW01000047_00033 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pMUJW01000047_00033 - 0.087 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pMUJW01000047_00034 - 1.5e-28 100.5 13.6 2e-28 100.2 13.6 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pMUJW01000047_00034 - 0.0054 16.8 0.6 0.021 15.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pMUJW01000047_00034 - 0.011 16.4 5.4 0.011 16.4 5.4 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor KNOX2 PF03791.13 pMUJW01000047_00034 - 0.066 12.7 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain VWA_2 PF13519.6 pMUJW01000047_00034 - 0.069 13.8 0.9 0.069 13.8 0.9 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain THOC7 PF05615.13 pMUJW01000047_00034 - 2.4 8.4 11.3 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pMUJW01000047_00034 - 5.4 6.4 7.5 1.7 8.1 3.5 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DHR10 PF18595.1 pMUJW01000047_00034 - 5.9 7.0 14.8 0.66 10.1 6.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TrbL PF04610.14 pMUJW01000047_00035 - 3.6e-30 105.4 29.1 3.6e-30 105.4 29.1 1.7 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pMUJW01000047_00035 - 0.12 12.2 1.4 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pMUJW01000047_00035 - 1.3 10.0 5.2 2.2 9.3 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 MerC PF03203.14 pMUJW01000047_00035 - 4.9 7.6 19.7 25 5.4 19.7 2.1 1 1 0 1 1 1 0 MerC mercury resistance protein Trep_dent_lipo PF09710.10 pMUJW01000047_00036 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pMUJW01000047_00036 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pMUJW01000047_00037 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pMUJW01000047_00037 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pMUJW01000047_00038 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pMUJW01000047_00038 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pMUJW01000047_00039 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pMUJW01000047_00039 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pMUJW01000047_00040 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pMUJW01000047_00040 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pMUJW01000047_00040 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pMUJW01000047_00040 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pMUJW01000047_00040 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pMUJW01000047_00040 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pMUJW01000047_00040 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pMUJW01000047_00040 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pMUJW01000047_00040 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pMUJW01000047_00040 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pMUJW01000047_00040 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pMUJW01000047_00040 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pMUJW01000047_00040 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pMUJW01000047_00040 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pMUJW01000047_00040 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pMUJW01000047_00040 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pMUJW01000047_00040 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pMUJW01000047_00040 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pMUJW01000047_00040 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pMUJW01000047_00040 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pMUJW01000047_00040 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pMUJW01000047_00040 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pMUJW01000047_00040 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pMUJW01000047_00040 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pMUJW01000047_00040 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pMUJW01000047_00040 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pMUJW01000047_00040 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pMUJW01000047_00040 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pMUJW01000047_00040 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pMUJW01000047_00040 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pMUJW01000047_00040 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pMUJW01000047_00041 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pMUJW01000047_00041 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pMUJW01000047_00041 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pMUJW01000047_00041 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Phage_holin_3_6 PF07332.11 pMUJW01000047_00041 - 0.22 11.6 0.2 0.35 10.9 0.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cag12 PF13117.6 pMUJW01000047_00042 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pMUJW01000047_00042 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pMUJW01000047_00042 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pMUJW01000047_00042 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pMUJW01000047_00043 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pMUJW01000047_00044 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pMUJW01000047_00044 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pMUJW01000047_00044 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pMUJW01000047_00046 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pMUJW01000047_00047 - 1.2e-96 324.2 8.2 1.7e-96 323.8 8.2 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pMUJW01000047_00047 - 1.8e-12 47.4 0.4 1e-11 44.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pMUJW01000047_00047 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pMUJW01000047_00047 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pMUJW01000047_00047 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pMUJW01000047_00047 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pMUJW01000047_00047 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pMUJW01000047_00047 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pMUJW01000047_00047 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pMUJW01000047_00047 - 0.088 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pMUJW01000047_00047 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pMUJW01000047_00047 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pMUJW01000047_00047 - 0.55 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pMUJW01000047_00047 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pMUJW01000047_00047 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pMUJW01000047_00047 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pMUJW01000047_00047 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pMUJW01000047_00048 - 5.3e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pMUJW01000047_00048 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pMUJW01000047_00050 - 1.8e-58 197.3 0.3 2.5e-58 196.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pMUJW01000047_00050 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pMUJW01000047_00050 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pMUJW01000047_00050 - 2.2e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pMUJW01000047_00050 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pMUJW01000047_00050 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pMUJW01000047_00050 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pMUJW01000047_00050 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pMUJW01000047_00050 - 0.049 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Mur_ligase_M PF08245.12 pNAAE01000001_00001 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 pNAAE01000001_00001 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF4570 PF15134.6 pNAAE01000001_00002 - 0.17 11.9 1.7 0.32 11.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) CTP_transf_3 PF02348.19 pNAAE01000001_00003 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 pNAAE01000001_00003 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 pNAAE01000001_00003 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain PALP PF00291.25 pNAAE01000001_00004 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 pNAAE01000001_00004 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 pNAAE01000001_00004 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain LpxK PF02606.14 pNAAE01000001_00005 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 pNAAE01000001_00005 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAD_synthase PF02540.17 pNAAE01000001_00006 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 pNAAE01000001_00006 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 pNAAE01000001_00006 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 pNAAE01000001_00006 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 pNAAE01000001_00006 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 pNAAE01000001_00006 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Lactamase_B PF00753.27 pNAAE01000001_00007 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 pNAAE01000001_00007 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1129 PF06570.11 pNAAE01000001_00008 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) adh_short_C2 PF13561.6 pNAAE01000001_00009 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 pNAAE01000001_00009 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 pNAAE01000001_00009 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 pNAAE01000001_00009 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DHDPS PF00701.22 pNAAE01000001_00010 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 pNAAE01000001_00010 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Peptidase_M16_C PF05193.21 pNAAE01000001_00011 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 pNAAE01000001_00011 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 pNAAE01000001_00011 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHO_dh PF01180.21 pNAAE01000001_00012 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 pNAAE01000001_00012 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 pNAAE01000001_00012 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family ABC_membrane PF00664.23 pNAAE01000001_00013 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 pNAAE01000001_00013 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 pNAAE01000001_00013 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 pNAAE01000001_00013 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 pNAAE01000001_00013 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 pNAAE01000001_00013 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 pNAAE01000001_00013 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 pNAAE01000001_00013 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 pNAAE01000001_00013 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 pNAAE01000001_00013 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 pNAAE01000001_00013 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase tRNA-synt_1e PF01406.19 pNAAE01000001_00014 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 pNAAE01000001_00014 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 pNAAE01000001_00014 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 pNAAE01000001_00014 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 pNAAE01000001_00014 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 pNAAE01000001_00014 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 pNAAE01000001_00014 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) MurJ PF03023.14 pNAAE01000001_00015 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 pNAAE01000001_00015 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 FapA PF03961.13 pNAAE01000001_00016 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 pNAAE01000001_00016 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 pNAAE01000001_00016 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 pNAAE01000001_00016 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HHH_5 PF14520.6 pNAAE01000001_00017 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 pNAAE01000001_00017 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 pNAAE01000001_00017 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 pNAAE01000001_00017 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 pNAAE01000001_00017 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 pNAAE01000001_00017 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 pNAAE01000001_00017 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 pNAAE01000001_00017 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 pNAAE01000001_00017 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 pNAAE01000001_00017 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 pNAAE01000001_00017 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 pNAAE01000001_00017 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Dala_Dala_lig_C PF07478.13 pNAAE01000001_00018 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 pNAAE01000001_00018 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 pNAAE01000001_00018 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 pNAAE01000001_00018 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 pNAAE01000001_00018 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 pNAAE01000001_00018 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PhdYeFM_antitox PF02604.19 pNAAE01000001_00019 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Mur_ligase_M PF08245.12 pNAAG01000003_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 pNAAG01000003_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 pNAAG01000003_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 pNAAG01000003_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 pNAAG01000003_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 pNAAG01000003_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 pNAAG01000003_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 pNAAG01000003_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 pNAAG01000003_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 pNAAG01000003_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 pNAAG01000003_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 pNAAG01000003_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 pNAAG01000003_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 pNAAG01000003_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 pNAAG01000003_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 pNAAG01000003_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 pNAAG01000003_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 pNAAG01000003_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 pNAAG01000003_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 pNAAG01000003_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 pNAAG01000003_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 pNAAG01000003_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 pNAAG01000003_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 pNAAG01000003_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 pNAAG01000003_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 pNAAG01000003_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 pNAAG01000003_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 pNAAG01000003_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 pNAAG01000003_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 pNAAG01000003_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 pNAAG01000003_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 pNAAG01000003_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 pNAAG01000003_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 pNAAG01000003_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 pNAAG01000003_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 pNAAG01000003_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 pNAAG01000003_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 pNAAG01000003_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 pNAAG01000003_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 pNAAG01000003_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 pNAAG01000003_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 pNAAG01000003_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 pNAAG01000003_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 pNAAG01000003_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 pNAAG01000003_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 pNAAG01000003_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 pNAAG01000003_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 pNAAG01000003_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 pNAAG01000003_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 pNAAG01000003_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 pNAAG01000003_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 pNAAG01000003_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 pNAAG01000003_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 pNAAG01000003_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 pNAAG01000003_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 pNAAG01000003_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 pNAAG01000003_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 pNAAG01000003_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 pNAAG01000003_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 pNAAG01000003_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 pNAAG01000003_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 pNAAG01000003_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 pNAAG01000003_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 pNAAG01000003_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 pNAAG01000003_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 pNAAG01000003_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 pNAAG01000003_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 pNAAG01000003_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 pNAAG01000003_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 pNAAG01000003_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 pNAAG01000003_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 pNAAG01000003_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 pNAAG01000003_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 pNAAG01000003_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 pNAAG01000003_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 pNAAG01000003_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 pNAAG01000003_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 pNAAG01000003_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 pNAAG01000003_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 pNAAG01000003_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 pNAAG01000003_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain MAF_flag10 PF01973.18 pNAAG01000032_00001 - 1.3e-43 148.6 1.0 2.7e-43 147.6 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF115 KASH_CCD PF14662.6 pNAAG01000032_00001 - 0.0075 16.1 0.5 0.037 13.9 0.5 2.1 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 pNAAG01000032_00001 - 0.072 13.3 4.3 0.33 11.2 2.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MAF_flag10 PF01973.18 pNAAG01000032_00002 - 1.5e-42 145.2 1.3 2.9e-42 144.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF115 PspA_IM30 PF04012.12 pNAAG01000032_00002 - 0.054 13.1 2.0 0.084 12.4 2.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family FliE PF02049.18 pNAAG01000032_00002 - 0.086 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Sec2p PF06428.11 pNAAG01000032_00002 - 0.26 11.3 7.2 0.83 9.7 7.2 1.9 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p eIF-4B PF06273.11 pNAAG01000032_00002 - 1.3 8.0 4.0 1.9 7.5 4.0 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Mur_ligase_M PF08245.12 pNAAH01000003_00002 - 3.6e-20 72.8 0.8 1.9e-19 70.4 0.1 2.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 pNAAH01000003_00002 - 0.0043 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Abhydrolase_1 PF00561.20 pNAAH01000003_00003 - 5.1e-09 36.2 0.0 3.3e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 pNAAH01000003_00003 - 6.4e-07 30.2 0.0 2.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 pNAAH01000003_00003 - 2.5e-05 23.7 0.0 3.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 pNAAH01000003_00003 - 0.0031 17.2 0.1 0.26 10.9 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 pNAAH01000003_00003 - 0.018 14.9 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.10 pNAAH01000003_00003 - 0.053 13.6 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rota_VP2 PF05087.12 pNAAH01000003_00003 - 0.056 11.6 0.0 0.069 11.3 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PhdYeFM_antitox PF02604.19 pNAAH01000003_00004 - 1.2e-08 34.6 0.2 1.4e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Dala_Dala_lig_C PF07478.13 pNAAH01000003_00005 - 2.6e-32 112.1 0.1 3.6e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 pNAAH01000003_00005 - 1.3e-20 73.8 0.0 1.1e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 pNAAH01000003_00005 - 1.2e-05 25.0 0.0 0.0089 15.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 pNAAH01000003_00005 - 0.00023 20.8 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 pNAAH01000003_00005 - 0.0015 18.6 0.1 0.11 12.5 0.1 2.9 1 1 1 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 pNAAH01000003_00005 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HHH_5 PF14520.6 pNAAH01000003_00006 - 2.8e-15 56.6 0.0 6.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_N PF01330.21 pNAAH01000003_00006 - 4.3e-10 39.5 0.1 3.1e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 pNAAH01000003_00006 - 2.2e-08 34.4 2.0 4.2e-08 33.5 2.0 1.5 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 pNAAH01000003_00006 - 4.7e-07 29.4 0.1 0.0027 17.5 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Ribosomal_S13 PF00416.22 pNAAH01000003_00006 - 5.6e-05 23.5 0.1 0.03 14.7 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S13/S18 HHH_2 PF12826.7 pNAAH01000003_00006 - 0.00086 19.4 0.0 1.8 8.7 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 pNAAH01000003_00006 - 0.00095 19.4 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 pNAAH01000003_00006 - 0.0011 19.5 0.7 0.0077 16.8 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 pNAAH01000003_00006 - 0.0083 16.4 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family IMS_HHH PF11798.8 pNAAH01000003_00006 - 0.019 15.3 0.1 0.19 12.1 0.1 2.6 2 1 0 2 2 2 0 IMS family HHH motif HHH_8 PF14716.6 pNAAH01000003_00006 - 0.022 15.1 0.2 0.45 10.9 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 pNAAH01000003_00006 - 0.032 14.1 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda FapA PF03961.13 pNAAH01000003_00007 - 3.5e-30 105.0 37.0 5.2e-30 104.5 36.7 1.4 1 1 0 1 1 1 1 Flagellar Assembly Protein A FAM76 PF16046.5 pNAAH01000003_00007 - 0.027 13.8 8.1 0.061 12.7 8.1 1.6 1 0 0 1 1 1 0 FAM76 protein Viral_P18 PF04521.13 pNAAH01000003_00007 - 0.15 11.8 2.3 21 4.9 0.0 3.5 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein APG6_N PF17675.1 pNAAH01000003_00007 - 0.29 11.7 8.6 1.4 9.5 8.6 2.3 1 0 0 1 1 1 0 Apg6 coiled-coil region MurJ PF03023.14 pNAAH01000003_00008 - 1e-91 307.8 60.1 1.7e-91 307.1 60.1 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Bunya_G2 PF03563.13 pNAAH01000003_00008 - 1.5 8.0 7.4 3.1 7.0 7.4 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 tRNA-synt_1e PF01406.19 pNAAH01000003_00009 - 1e-109 366.5 0.6 1.7e-109 365.8 0.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 pNAAH01000003_00009 - 9e-14 51.0 1.5 3.4e-07 29.3 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 pNAAH01000003_00009 - 1.1e-07 32.2 4.6 7.2e-06 26.4 1.4 2.8 2 0 0 2 2 2 2 DALR domain tRNA-synt_1 PF00133.22 pNAAH01000003_00009 - 1.6e-06 26.7 0.0 0.00047 18.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 pNAAH01000003_00009 - 0.0002 20.4 0.2 0.02 13.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) Helicase_Sgs1 PF11408.8 pNAAH01000003_00009 - 0.0023 18.0 0.0 0.0076 16.3 0.0 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase DUF4919 PF16266.5 pNAAH01000003_00009 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) ABC_membrane PF00664.23 pNAAH01000003_00010 - 4.4e-48 164.3 8.4 5.8e-48 163.9 8.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 pNAAH01000003_00010 - 4.9e-31 108.1 0.1 9e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 pNAAH01000003_00010 - 6e-10 38.9 5.9 1.4e-08 34.5 5.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 pNAAH01000003_00010 - 0.00081 19.3 0.2 0.0019 18.1 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 pNAAH01000003_00010 - 0.0025 18.1 0.4 0.027 14.7 0.4 2.4 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 pNAAH01000003_00010 - 0.0056 16.9 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 pNAAH01000003_00010 - 0.0098 15.6 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain ATP-synt_I PF03899.15 pNAAH01000003_00010 - 0.024 15.0 0.3 0.024 15.0 0.3 3.4 3 0 0 3 3 3 0 ATP synthase I chain AAA_16 PF13191.6 pNAAH01000003_00010 - 0.035 14.5 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 pNAAH01000003_00010 - 0.094 12.5 0.7 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 pNAAH01000003_00010 - 0.11 12.6 0.9 0.53 10.4 0.9 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 pNAAH01000003_00011 - 2.7e-72 243.5 0.1 3.1e-72 243.3 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiI PF02568.14 pNAAH01000003_00011 - 0.031 13.9 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PcrB PF01884.17 pNAAH01000003_00011 - 0.069 12.6 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family Peptidase_M16_C PF05193.21 pNAAH01000003_00012 - 7.8e-31 107.5 1.1 1.1e-29 103.8 0.3 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 pNAAH01000003_00012 - 8.6e-25 87.5 0.0 1.9e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) LuxS PF02664.15 pNAAH01000003_00012 - 0.022 14.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) DHDPS PF00701.22 pNAAH01000003_00013 - 1.8e-88 296.0 0.2 2.3e-88 295.7 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CTK3 PF12243.8 pNAAH01000003_00013 - 0.068 13.2 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 adh_short_C2 PF13561.6 pNAAH01000003_00014 - 3.4e-59 200.2 1.1 4.2e-59 200.0 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 pNAAH01000003_00014 - 1.6e-33 115.8 2.4 1.9e-33 115.6 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 pNAAH01000003_00014 - 0.00012 22.1 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 KR domain RRM_3 PF08777.11 pNAAH01000003_00014 - 0.016 15.3 0.3 3.1 7.9 0.2 2.3 2 0 0 2 2 2 0 RNA binding motif DUF1129 PF06570.11 pNAAH01000003_00015 - 0.24 10.9 5.2 0.67 9.4 3.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.27 pNAAH01000003_00016 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 pNAAH01000003_00016 - 0.00014 21.5 0.2 0.00018 21.1 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_synthase PF02540.17 pNAAH01000003_00017 - 3.7e-79 265.2 0.1 4.2e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 NAD synthase RPAP1_N PF08621.10 pNAAH01000003_00017 - 6.6e-06 25.8 0.6 0.00013 21.7 0.7 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal tRNA_Me_trans PF03054.16 pNAAH01000003_00017 - 1.2e-05 24.3 0.0 0.00092 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 pNAAH01000003_00017 - 0.00031 20.3 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 pNAAH01000003_00017 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 pNAAH01000003_00017 - 0.04 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family LpxK PF02606.14 pNAAH01000003_00018 - 1.6e-38 132.6 0.0 5.4e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA PF00004.29 pNAAH01000003_00018 - 0.051 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 pNAAH01000003_00019 - 1.4e-09 37.8 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 pNAAH01000003_00019 - 2.1e-07 31.1 0.3 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Threonine synthase N terminus CbiA PF01656.23 pNAAH01000003_00019 - 0.039 14.0 0.0 0.59 10.2 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CTP_transf_3 PF02348.19 pNAAH01000003_00020 - 9.6e-46 156.5 0.3 1.2e-45 156.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 pNAAH01000003_00020 - 1.3e-05 25.6 0.0 1.6e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain HTH_19 PF12844.7 pNAAH01000003_00020 - 0.0091 16.0 2.0 0.047 13.7 0.4 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain MAF_flag10 PF01973.18 pNAAH01000019_00001 - 3.7e-42 143.9 0.7 5.4e-42 143.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF115 Med15_fungi PF05397.12 pNAAH01000019_00001 - 0.011 16.0 0.7 0.15 12.4 0.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 GTP_EFTU PF00009.27 pNC_006134_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pNC_006134_00001 - 3.7e-23 81.6 0.0 9.7e-23 80.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pNC_006134_00001 - 1.2e-16 60.5 0.0 3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pNC_006134_00001 - 1.3e-13 50.8 0.1 2.8e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pNC_006134_00001 - 1.3e-06 28.5 0.2 4.6e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RF3_C PF16658.5 pNC_006134_00001 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 pNC_006134_00001 - 0.012 16.0 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Septin PF00735.18 pNC_006134_00001 - 0.02 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pNC_006134_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pNC_006134_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pNC_006134_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pNC_006134_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pNC_006134_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 pNC_006134_00005 - 0.019 15.1 0.2 3 8.0 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pNC_006134_00006 - 0.0057 16.0 1.4 0.0057 16.0 1.4 2.0 3 0 0 3 3 3 1 Putative Flagellin, Flp1-like, domain vMSA PF00695.19 pNC_006134_00006 - 1.9 7.5 5.4 2.3 7.2 5.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LysE PF01810.18 pNC_006134_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pNC_006134_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pNC_006134_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pNC_006134_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pNC_006134_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pNC_006134_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pNC_006134_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pNC_006134_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pNC_006134_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pNC_006134_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pNC_006134_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pNC_006134_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pNC_006134_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pNC_006134_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pNC_006134_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pNC_006134_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pNC_006134_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pNC_006134_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pNC_006134_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pNC_006134_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pNC_006134_00012 - 3.1e-16 59.1 2.7 4.1e-16 58.6 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pNC_006134_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pNC_006134_00012 - 1e-06 29.1 0.2 4.8e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pNC_006134_00012 - 9.2e-06 25.5 1.8 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pNC_006134_00012 - 3.7e-05 24.2 0.7 0.00032 21.2 0.2 3.0 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pNC_006134_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pNC_006134_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pNC_006134_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pNC_006134_00014 - 0.00022 21.6 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pNC_006134_00014 - 0.0032 17.7 0.0 0.0079 16.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pNC_006134_00014 - 0.0091 16.0 0.3 0.017 15.2 0.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Relaxase PF03432.14 pNC_006134_00015 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pNC_006134_00016 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pNC_006134_00016 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pNC_006134_00016 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pNC_006134_00016 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pNC_006134_00016 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pNC_006134_00017 - 0.16 11.8 9.8 0.18 11.7 6.9 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ZYG-11_interact PF05884.12 pNC_006134_00017 - 0.22 10.9 0.5 0.26 10.7 0.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 ESP PF16590.5 pNC_006134_00017 - 0.6 10.4 5.4 0.25 11.6 0.5 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide Toprim_3 PF13362.6 pNC_006134_00019 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pNC_006134_00019 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pNC_006134_00019 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pNC_006134_00019 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pNC_006134_00020 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Sdh_cyt PF01127.22 pNC_006134_00021 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pNC_006134_00021 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pNC_006134_00021 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pNC_006134_00023 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pNC_006134_00024 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pNC_006134_00025 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pNC_006134_00025 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pNC_006134_00025 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pNC_006134_00025 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pNC_006134_00025 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pNC_006134_00025 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pNC_006134_00025 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pNC_006134_00026 - 2.5e-34 118.5 0.6 3.3e-34 118.1 0.6 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pNC_006134_00026 - 0.025 14.3 0.6 9.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pNC_006134_00026 - 0.05 13.6 4.8 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pNC_006134_00026 - 0.16 11.9 0.7 0.16 11.9 0.7 2.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pNC_006134_00027 - 0.00056 20.0 0.0 0.0014 18.8 0.0 1.8 1 1 1 2 2 2 2 CRISPR associated protein Cas2 TrbC PF04956.13 pNC_006134_00029 - 6.2e-13 48.8 6.8 6.6e-13 48.7 6.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pNC_006134_00029 - 0.61 9.9 6.3 1.3 8.9 6.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pNC_006134_00030 - 7.1e-51 173.2 0.4 1.6e-50 172.1 0.4 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pNC_006134_00030 - 2.6e-21 75.7 1.0 4.4e-21 74.9 1.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pNC_006134_00030 - 0.046 13.2 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pNC_006134_00031 - 1.8e-31 108.5 0.0 2.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) Y_Y_Y PF07495.13 pNC_006134_00031 - 0.1 12.6 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Y_Y_Y domain PBECR2 PF18810.1 pNC_006134_00032 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pNC_006134_00033 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pNC_006134_00034 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pNC_006134_00034 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pNC_006134_00034 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pNC_006134_00034 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pNC_006134_00035 - 1e-28 101.1 13.2 1.4e-28 100.6 13.2 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pNC_006134_00035 - 0.0082 16.3 2.4 0.021 15.0 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pNC_006134_00035 - 0.016 15.9 0.9 0.036 14.7 0.2 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain KMP11 PF03037.16 pNC_006134_00035 - 0.02 15.7 0.1 0.17 12.7 0.0 2.6 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 AATF-Che1 PF13339.6 pNC_006134_00035 - 0.023 15.3 12.3 0.028 15.1 5.0 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Tissue_fac PF01108.17 pNC_006134_00035 - 0.029 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Tissue factor Allexi_40kDa PF05549.11 pNC_006134_00035 - 1.2 8.6 6.3 1.2 8.6 2.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pNC_006134_00036 - 1.4e-29 103.5 34.4 1.4e-29 103.5 34.4 1.7 1 1 1 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pNC_006134_00036 - 0.097 12.5 1.3 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Trep_dent_lipo PF09710.10 pNC_006134_00037 - 0.034 13.1 1.0 0.031 13.2 1.0 1.2 1 1 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) La_HTH_kDCL PF18177.1 pNC_006134_00037 - 0.19 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain PsbT PF01405.17 pNC_006134_00037 - 1.1 9.1 5.2 1.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pNC_006134_00038 - 1.6e-52 178.5 0.5 1.7e-52 178.4 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pNC_006134_00038 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pNC_006134_00039 - 4.2e-56 190.0 1.7 6.7e-56 189.3 1.7 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TraE PF05309.11 pNC_006134_00039 - 0.022 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 TraE protein Rho_RNA_bind PF07497.12 pNC_006134_00039 - 0.068 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain TrbI PF03743.14 pNC_006134_00040 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pNC_006134_00040 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pNC_006134_00041 - 1.5e-54 184.9 0.0 1.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pNC_006134_00041 - 7e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pNC_006134_00041 - 0.00011 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pNC_006134_00041 - 0.00029 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pNC_006134_00041 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pNC_006134_00041 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pNC_006134_00041 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 pNC_006134_00041 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pNC_006134_00041 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pNC_006134_00041 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pNC_006134_00041 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pNC_006134_00041 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pNC_006134_00041 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pNC_006134_00041 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pNC_006134_00041 - 0.022 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pNC_006134_00041 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pNC_006134_00041 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pNC_006134_00041 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pNC_006134_00041 - 0.039 14.0 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pNC_006134_00041 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pNC_006134_00041 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 pNC_006134_00041 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 pNC_006134_00041 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pNC_006134_00041 - 0.066 11.8 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pNC_006134_00041 - 0.074 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pNC_006134_00041 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pNC_006134_00041 - 0.097 12.6 0.5 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pNC_006134_00041 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pNC_006134_00041 - 0.13 12.8 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 pNC_006134_00041 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pNC_006134_00041 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pNC_006134_00041 - 0.35 11.3 3.8 0.37 11.3 1.3 2.0 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pNC_006134_00042 - 1.4e-105 353.8 0.1 1.9e-105 353.4 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pNC_006134_00042 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pNC_006134_00042 - 6.2e-16 58.3 0.0 1.1e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Cag12 PF13117.6 pNC_006134_00043 - 1e-16 61.2 0.1 1.3e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pNC_006134_00043 - 0.062 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pNC_006134_00044 - 9.5e-39 132.8 1.2 1.2e-38 132.5 1.2 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pNC_006134_00045 - 0.028 14.2 2.2 0.033 14.0 0.3 2.0 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pNC_006134_00045 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family TACC_C PF05010.14 pNC_006134_00045 - 2.3 8.0 10.0 3.6 7.3 7.9 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 pNC_006134_00045 - 4.6 7.4 12.1 50 4.0 9.2 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT20 PF14931.6 pNC_006134_00045 - 5.4 7.2 10.4 1.3 9.2 0.8 3.4 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CdhD PF03599.16 pNC_006134_00047 - 0.0071 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Redoxin PF08534.10 pNC_006134_00047 - 0.028 14.1 0.9 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Redoxin YnfE PF17452.2 pNC_006134_00047 - 0.12 12.6 0.1 0.12 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized YnfE-like Topoisom_bac PF01131.20 pNC_006134_00048 - 2.7e-97 326.4 7.4 3.8e-97 325.9 7.4 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pNC_006134_00048 - 7.1e-12 45.5 2.2 1.4e-11 44.5 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pNC_006134_00048 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pNC_006134_00048 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pNC_006134_00048 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pNC_006134_00048 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pNC_006134_00048 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pNC_006134_00048 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pNC_006134_00048 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 pNC_006134_00048 - 0.096 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain EF-hand_8 PF13833.6 pNC_006134_00048 - 0.1 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair HTH_34 PF13601.6 pNC_006134_00048 - 0.44 10.8 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pNC_006134_00048 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pNC_006134_00048 - 0.63 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pNC_006134_00048 - 0.74 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pNC_006134_00048 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pNC_006134_00048 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pNC_006134_00049 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pNC_006134_00049 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pNC_006135_00001 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pNC_006135_00001 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pNC_006135_00001 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pNC_006135_00001 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pNC_006135_00001 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pNC_006135_00001 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pNC_006135_00001 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pNC_006135_00001 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pNC_006135_00001 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pNC_006135_00001 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pNC_006135_00002 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pNC_006135_00004 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pNC_006135_00004 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pNC_006135_00005 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pNC_006135_00005 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pNC_006135_00006 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pNC_006135_00007 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pNC_006135_00007 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pNC_006135_00007 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pNC_006135_00007 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pNC_006135_00007 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pNC_006135_00007 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pNC_006135_00007 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pNC_006135_00008 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pNC_006135_00008 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pNC_006135_00008 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pNC_006135_00008 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pNC_006135_00008 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pNC_006135_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pNC_006135_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pNC_006135_00010 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pNC_006135_00010 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pNC_006135_00010 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pNC_006135_00010 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pNC_006135_00010 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pNC_006135_00011 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pNC_006135_00012 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pNC_006135_00012 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pNC_006135_00012 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pNC_006135_00012 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pNC_006135_00012 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pNC_006135_00013 - 0.0008 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pNC_006135_00013 - 0.033 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pNC_006135_00014 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pNC_006135_00015 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pNC_006135_00015 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pNC_006135_00015 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pNC_006135_00015 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pNC_006135_00015 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pNC_006135_00016 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pNC_006135_00016 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pNC_006135_00016 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pNC_006135_00018 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pNC_006135_00019 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pNC_006135_00019 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pNC_006135_00019 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pNC_006135_00019 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pNC_006135_00020 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pNC_006135_00021 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pNC_006135_00021 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pNC_006135_00021 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pNC_006135_00021 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pNC_006135_00022 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pNC_006135_00022 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pNC_006135_00022 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pNC_006135_00024 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pNC_006135_00025 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pNC_006135_00026 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pNC_006135_00026 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pNC_006135_00026 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pNC_006135_00026 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pNC_006135_00026 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pNC_006135_00026 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pNC_006135_00026 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pNC_006135_00027 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pNC_006135_00027 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pNC_006135_00027 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pNC_006135_00027 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pNC_006135_00028 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pNC_006135_00028 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pNC_006135_00030 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pNC_006135_00030 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pNC_006135_00031 - 4.8e-50 170.5 0.5 1.1e-49 169.4 0.5 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pNC_006135_00031 - 6.8e-21 74.3 1.2 1.2e-20 73.5 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pNC_006135_00031 - 0.045 13.2 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pNC_006135_00033 - 1.5e-21 76.7 0.1 2.6e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pNC_006135_00034 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pNC_006135_00034 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pNC_006135_00034 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pNC_006135_00034 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pNC_006135_00034 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pNC_006135_00034 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pNC_006135_00035 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pNC_006135_00036 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pNC_006135_00036 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pNC_006135_00037 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pNC_006135_00037 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pNC_006135_00037 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pNC_006135_00037 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 pNC_006135_00037 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 pNC_006135_00037 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pNC_006135_00037 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pNC_006135_00038 - 1.4e-31 110.0 32.1 1.9e-31 109.5 32.1 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Trep_dent_lipo PF09710.10 pNC_006135_00039 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pNC_006135_00039 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pNC_006135_00040 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pNC_006135_00040 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pNC_006135_00041 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pNC_006135_00041 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pNC_006135_00042 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pNC_006135_00042 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pNC_006135_00043 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pNC_006135_00043 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pNC_006135_00043 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pNC_006135_00043 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pNC_006135_00043 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pNC_006135_00043 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pNC_006135_00043 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pNC_006135_00043 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pNC_006135_00043 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pNC_006135_00043 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pNC_006135_00043 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pNC_006135_00043 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pNC_006135_00043 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pNC_006135_00043 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pNC_006135_00043 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pNC_006135_00043 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pNC_006135_00043 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pNC_006135_00043 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pNC_006135_00043 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pNC_006135_00043 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pNC_006135_00043 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pNC_006135_00043 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pNC_006135_00043 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pNC_006135_00043 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pNC_006135_00043 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pNC_006135_00043 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pNC_006135_00043 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pNC_006135_00043 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pNC_006135_00043 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pNC_006135_00043 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pNC_006135_00043 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pNC_006135_00044 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pNC_006135_00044 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pNC_006135_00044 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pNC_006135_00044 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pNC_006135_00045 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pNC_006135_00045 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pNC_006135_00045 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pNC_006135_00045 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pNC_006135_00046 - 5.7e-29 101.1 0.5 6.4e-29 100.9 0.5 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pNC_006135_00047 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pNC_006135_00047 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pNC_006135_00047 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pNC_006135_00049 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pNC_006135_00050 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pNC_006135_00050 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pNC_006135_00050 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pNC_006135_00050 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pNC_006135_00050 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pNC_006135_00050 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pNC_006135_00050 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pNC_006135_00050 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pNC_006135_00050 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pNC_006135_00050 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pNC_006135_00050 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pNC_006135_00050 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pNC_006135_00050 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pNC_006135_00050 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pNC_006135_00050 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pNC_006135_00050 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pNC_006135_00050 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pNC_006135_00051 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pNC_006135_00051 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain Acetyltransf_7 PF13508.7 pNC_007141_00002 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pNC_007141_00002 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pNC_007141_00003 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pNC_007141_00004 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pNC_007141_00004 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pNC_007141_00004 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pNC_007141_00004 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pNC_007141_00004 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pNC_007141_00005 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pNC_007141_00005 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pNC_007141_00005 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pNC_007141_00007 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pNC_007141_00008 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pNC_007141_00008 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pNC_007141_00008 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pNC_007141_00008 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pNC_007141_00009 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pNC_007141_00010 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pNC_007141_00010 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pNC_007141_00010 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pNC_007141_00010 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pNC_007141_00011 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pNC_007141_00011 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pNC_007141_00011 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pNC_007141_00013 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pNC_007141_00014 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pNC_007141_00015 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pNC_007141_00015 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pNC_007141_00015 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pNC_007141_00015 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pNC_007141_00015 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pNC_007141_00015 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pNC_007141_00015 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pNC_007141_00016 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pNC_007141_00016 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pNC_007141_00016 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pNC_007141_00016 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pNC_007141_00017 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pNC_007141_00017 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pNC_007141_00019 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pNC_007141_00019 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pNC_007141_00020 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pNC_007141_00020 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pNC_007141_00020 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pNC_007141_00021 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pNC_007141_00022 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pNC_007141_00022 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pNC_007141_00022 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pNC_007141_00022 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pNC_007141_00022 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pNC_007141_00022 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pNC_007141_00023 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pNC_007141_00024 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pNC_007141_00024 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pNC_007141_00025 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pNC_007141_00025 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pNC_007141_00025 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pNC_007141_00025 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 pNC_007141_00025 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 pNC_007141_00025 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pNC_007141_00025 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pNC_007141_00026 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pNC_007141_00026 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pNC_007141_00026 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pNC_007141_00027 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pNC_007141_00027 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pNC_007141_00028 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pNC_007141_00028 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pNC_007141_00029 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pNC_007141_00029 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pNC_007141_00030 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pNC_007141_00030 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pNC_007141_00031 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pNC_007141_00031 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pNC_007141_00031 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pNC_007141_00031 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pNC_007141_00031 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pNC_007141_00031 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pNC_007141_00031 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pNC_007141_00031 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pNC_007141_00031 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pNC_007141_00031 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pNC_007141_00031 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pNC_007141_00031 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pNC_007141_00031 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pNC_007141_00031 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pNC_007141_00031 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pNC_007141_00031 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pNC_007141_00031 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pNC_007141_00031 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pNC_007141_00031 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pNC_007141_00031 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pNC_007141_00031 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pNC_007141_00031 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pNC_007141_00031 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pNC_007141_00031 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pNC_007141_00031 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pNC_007141_00031 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pNC_007141_00031 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pNC_007141_00031 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pNC_007141_00031 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pNC_007141_00031 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pNC_007141_00031 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pNC_007141_00032 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pNC_007141_00032 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pNC_007141_00032 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pNC_007141_00032 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pNC_007141_00033 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pNC_007141_00033 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pNC_007141_00033 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pNC_007141_00033 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pNC_007141_00034 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pNC_007141_00035 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pNC_007141_00035 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pNC_007141_00035 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pNC_007141_00037 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pNC_007141_00038 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pNC_007141_00038 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pNC_007141_00038 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pNC_007141_00038 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pNC_007141_00038 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pNC_007141_00038 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pNC_007141_00038 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pNC_007141_00038 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pNC_007141_00038 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pNC_007141_00038 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pNC_007141_00038 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pNC_007141_00038 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pNC_007141_00038 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pNC_007141_00038 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pNC_007141_00038 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pNC_007141_00038 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pNC_007141_00038 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pNC_007141_00039 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pNC_007141_00039 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pNC_007141_00041 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pNC_007141_00041 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pNC_007141_00041 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pNC_007141_00041 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pNC_007141_00041 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pNC_007141_00041 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pNC_007141_00041 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pNC_007141_00041 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pNC_007141_00041 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pNC_007141_00041 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pNC_007141_00042 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pNC_007141_00044 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pNC_007141_00044 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain CtsR_C PF17727.1 pNC_007141_00045 - 0.039 14.1 0.2 4.3 7.5 0.0 2.4 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pNC_007141_00046 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DUF1516 PF07457.11 pNC_007141_00047 - 0.0042 17.3 0.4 0.0049 17.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1516) LysE PF01810.18 pNC_007141_00047 - 0.0049 16.4 0.1 0.0057 16.1 0.1 1.1 1 0 0 1 1 1 1 LysE type translocator DUF2873 PF11395.8 pNC_007141_00047 - 1 9.3 0.1 1 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2873) S1_2 PF13509.6 pNC_007141_00048 - 0.093 12.8 0.5 0.85 9.7 0.1 2.0 1 1 1 2 2 2 0 S1 domain DUF4044 PF13253.6 pNC_007141_00049 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pNC_007141_00049 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pNC_007141_00049 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pNC_007141_00049 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pNC_007141_00049 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pNC_007141_00050 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pNC_007141_00050 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pNC_007141_00051 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pNC_007141_00051 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pNC_007141_00051 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pNC_007141_00051 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pNC_007141_00051 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pNC_007141_00052 - 5.4e-07 29.9 1.0 5.9e-07 29.8 1.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG PDDEXK_9 PF08011.11 pNC_007141_00053 - 0.017 15.0 0.2 0.032 14.1 0.2 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF5445 PF17520.2 pNC_007141_00054 - 1 9.2 12.2 1.3 8.9 11.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5445) W2 PF02020.18 pNC_008790_00001 - 0.037 14.2 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Lip_prot_lig_C PF10437.9 pNC_008790_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pNC_008790_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain Flp1_like PF16982.5 pNC_008790_00003 - 0.015 14.7 2.9 0.015 14.7 2.9 2.1 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain LysE PF01810.18 pNC_008790_00004 - 0.0031 17.0 0.6 0.0062 16.0 0.6 1.5 1 1 0 1 1 1 1 LysE type translocator DUF1516 PF07457.11 pNC_008790_00004 - 0.0059 16.8 1.7 0.0069 16.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1516) Pallilysin PF18663.1 pNC_008790_00004 - 0.01 15.8 2.1 0.012 15.6 1.3 1.5 1 1 0 1 1 1 0 Pallilysin beta barrel domain DUF2178 PF09946.9 pNC_008790_00004 - 0.043 14.0 2.3 0.064 13.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF373 PF04123.13 pNC_008790_00004 - 0.062 12.7 2.8 0.069 12.6 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DHHC PF01529.20 pNC_008790_00004 - 0.65 10.1 7.6 0.37 10.9 5.1 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Saf_2TM PF18303.1 pNC_008790_00004 - 0.72 9.4 5.1 1.6 8.3 0.3 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF4044 PF13253.6 pNC_008790_00005 - 0.034 13.7 0.8 0.06 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pNC_008790_00005 - 0.061 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NPA PF16469.5 pNC_008790_00005 - 0.081 13.5 5.0 0.11 13.1 5.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DUF2070 PF09843.9 pNC_008790_00005 - 0.083 11.2 1.4 0.12 10.7 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pNC_008790_00005 - 8.7 6.1 13.5 0.14 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pNC_008790_00006 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pNC_008790_00006 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA_31 PF13614.6 pNC_008790_00007 - 4.7e-05 23.4 0.6 0.00095 19.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain CbiA PF01656.23 pNC_008790_00007 - 0.00045 20.3 0.8 0.0046 17.0 0.8 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 pNC_008790_00007 - 0.037 13.5 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pNC_008790_00007 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain ParA PF10609.9 pNC_008790_00007 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RHH_7 PF16777.5 pNC_008790_00008 - 4.5e-07 30.2 0.9 5e-07 30.0 0.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG SNF2_N PF00176.23 pNC_008790_00009 - 2.3e-16 59.5 1.6 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pNC_008790_00009 - 4.9e-08 33.2 8.3 4.9e-08 33.2 8.3 4.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pNC_008790_00009 - 9.9e-07 29.1 0.2 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pNC_008790_00009 - 7.5e-06 25.8 1.6 0.0012 18.6 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pNC_008790_00009 - 2.9e-05 24.5 0.7 0.00032 21.2 0.2 3.2 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Acetyltransf_7 PF13508.7 pNC_008790_00010 - 0.00079 19.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pNC_008790_00010 - 0.032 14.4 0.1 0.066 13.5 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Relaxase PF03432.14 pNC_008790_00011 - 1.9e-10 40.8 7.0 1.9e-10 40.8 7.0 2.5 2 0 0 2 2 2 2 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pNC_008790_00012 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pNC_008790_00012 - 0.052 13.7 2.0 0.072 13.2 1.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) U3_assoc_6 PF08640.11 pNC_008790_00012 - 0.29 11.3 8.6 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 NLRC4_HD PF17889.1 pNC_008790_00012 - 0.29 11.5 5.9 1.5 9.2 2.1 2.2 1 1 1 2 2 2 0 NLRC4 helical domain DndE PF08870.11 pNC_008790_00012 - 0.35 11.1 5.8 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE Sds3 PF08598.11 pNC_008790_00013 - 0.031 14.3 6.1 0.036 14.1 6.1 1.2 1 0 0 1 1 1 0 Sds3-like CdvA PF18822.1 pNC_008790_00013 - 0.22 11.3 8.9 0.25 11.2 6.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pNC_008790_00013 - 0.52 10.6 5.3 0.28 11.5 0.6 2.0 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF2400 PF09674.10 pNC_008790_00015 - 0.18 11.8 5.5 0.38 10.7 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Toprim_3 PF13362.6 pNC_008790_00016 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pNC_008790_00016 - 0.082 12.9 0.3 0.37 10.8 0.3 2.1 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pNC_008790_00016 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pNC_008790_00016 - 0.17 12.5 4.7 0.87 10.2 0.4 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pNC_008790_00017 - 0.0072 16.3 0.2 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4223) UBA_6 PF18039.1 pNC_008790_00018 - 0.02 14.8 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 UBA-like domain DUF3606 PF12244.8 pNC_008790_00018 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) ZapB PF06005.12 pNC_008790_00018 - 0.051 14.0 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Lig_C PF18330.1 pNC_008790_00018 - 0.097 12.7 0.0 0.098 12.7 0.0 1.0 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Sdh_cyt PF01127.22 pNC_008790_00019 - 0.0064 16.5 2.3 0.0084 16.1 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2TM PF13239.6 pNC_008790_00019 - 0.36 11.2 4.1 0.49 10.7 4.1 1.2 1 0 0 1 1 1 0 2TM domain DUF2633 PF11119.8 pNC_008790_00019 - 0.93 9.4 4.2 1.7 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pNC_008790_00021 - 1.7e-08 34.6 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pNC_008790_00022 - 6.7e-10 38.9 0.3 8.2e-10 38.6 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pNC_008790_00023 - 1.9e-14 53.7 0.0 5.8e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pNC_008790_00023 - 0.00072 19.0 0.0 0.0045 16.4 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pNC_008790_00023 - 0.0033 17.2 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 pNC_008790_00023 - 0.014 15.9 0.1 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 pNC_008790_00023 - 0.028 13.7 0.0 0.2 10.9 0.0 2.5 2 1 0 2 2 2 0 KaiC CbiA PF01656.23 pNC_008790_00023 - 0.2 11.7 2.1 0.77 9.8 1.9 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain VASP_tetra PF08776.11 pNC_008790_00023 - 3.9 7.1 6.1 13 5.4 0.1 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain Resolvase PF00239.21 pNC_008790_00024 - 3.3e-33 114.8 0.7 4.5e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pNC_008790_00024 - 0.022 14.5 0.7 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pNC_008790_00024 - 0.039 14.0 4.6 0.41 10.7 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Pox_A_type_inc PF04508.12 pNC_008790_00024 - 0.16 11.9 0.7 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CRISPR_Cas2 PF09827.9 pNC_008790_00025 - 0.00034 20.7 0.1 0.00085 19.5 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 Mitovir_RNA_pol PF05919.11 pNC_008790_00025 - 0.046 12.9 0.5 0.057 12.6 0.5 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TrbC PF04956.13 pNC_008790_00027 - 3.5e-13 49.6 6.7 4e-13 49.4 6.7 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pNC_008790_00027 - 0.17 11.8 4.4 0.23 11.3 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pNC_008790_00028 - 4.9e-50 170.5 0.5 1.2e-49 169.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pNC_008790_00028 - 7.3e-21 74.2 1.2 1.3e-20 73.4 1.2 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein HNOBA PF07701.14 pNC_008790_00028 - 0.048 13.1 0.1 0.098 12.1 0.1 1.4 1 0 0 1 1 1 0 Heme NO binding associated Phage_pRha PF09669.10 pNC_008790_00029 - 2e-29 102.0 0.1 3.3e-29 101.3 0.1 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF3251 PF11622.8 pNC_008790_00030 - 0.079 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FapA PF03961.13 pNC_008790_00030 - 0.11 11.0 14.1 0.014 14.0 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 pNC_008790_00030 - 1 9.6 11.7 0.062 13.5 3.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.9 pNC_008790_00030 - 1.7 8.6 14.4 0.051 13.5 3.7 2.8 3 0 0 3 3 3 0 Axonemal dynein light chain DUF5082 PF16888.5 pNC_008790_00030 - 3.6 7.9 14.4 3 8.1 3.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF465 PF04325.13 pNC_008790_00030 - 4.6 7.4 9.4 13 5.9 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) SSB PF00436.25 pNC_008790_00031 - 2.8e-25 88.3 0.1 3.6e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pNC_008790_00032 - 0.00046 19.9 6.9 0.00048 19.9 2.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pNC_008790_00032 - 0.0053 17.3 1.0 0.0062 17.1 1.0 1.1 1 0 0 1 1 1 1 FliG N-terminal domain T4SS PF07996.11 pNC_008790_00033 - 7.9e-29 101.5 13.4 1e-28 101.1 13.4 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pNC_008790_00033 - 0.0081 16.3 0.6 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) AATF-Che1 PF13339.6 pNC_008790_00033 - 0.014 16.1 5.0 0.014 16.1 5.0 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor VWA_2 PF13519.6 pNC_008790_00033 - 0.043 14.5 0.8 0.043 14.5 0.8 2.0 2 1 0 2 2 2 0 von Willebrand factor type A domain KNOX2 PF03791.13 pNC_008790_00033 - 0.07 12.6 0.2 7.2 6.2 0.1 2.6 2 0 0 2 2 2 0 KNOX2 domain THOC7 PF05615.13 pNC_008790_00033 - 1.2 9.4 11.3 1.6 9.0 0.2 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 Allexi_40kDa PF05549.11 pNC_008790_00033 - 3.5 7.1 7.2 1.2 8.6 3.3 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein TrbL PF04610.14 pNC_008790_00034 - 3.2e-31 108.8 32.1 3.2e-31 108.8 32.1 1.8 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pNC_008790_00034 - 0.18 11.7 1.6 1 9.2 0.1 2.6 2 0 0 2 2 2 0 T-cell leukemia translocation-altered AIM3 PF17096.5 pNC_008790_00034 - 1.6 9.7 5.2 2.7 9.0 5.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Trep_dent_lipo PF09710.10 pNC_008790_00035 - 0.016 14.1 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) PsbT PF01405.17 pNC_008790_00035 - 1.1 9.1 5.2 1.7 8.5 5.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre T protein VirB8 PF04335.13 pNC_008790_00036 - 2e-52 178.1 0.5 2.2e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pNC_008790_00036 - 0.012 15.6 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pNC_008790_00037 - 3.2e-55 187.1 1.3 5.3e-55 186.4 1.3 1.3 1 1 0 1 1 1 1 Conjugal transfer protein DUF4354 PF14263.6 pNC_008790_00037 - 0.086 12.7 0.3 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) TrbI PF03743.14 pNC_008790_00038 - 3.4e-48 164.0 0.1 5.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pNC_008790_00038 - 0.028 13.5 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pNC_008790_00039 - 6.3e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pNC_008790_00039 - 6e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pNC_008790_00039 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pNC_008790_00039 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pNC_008790_00039 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pNC_008790_00039 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pNC_008790_00039 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TsaE PF02367.17 pNC_008790_00039 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pNC_008790_00039 - 0.0048 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pNC_008790_00039 - 0.0072 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pNC_008790_00039 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pNC_008790_00039 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 pNC_008790_00039 - 0.018 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 pNC_008790_00039 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 pNC_008790_00039 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 pNC_008790_00039 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 pNC_008790_00039 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 pNC_008790_00039 - 0.032 14.3 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 pNC_008790_00039 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 pNC_008790_00039 - 0.036 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 pNC_008790_00039 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 pNC_008790_00039 - 0.039 13.2 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pNC_008790_00039 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pNC_008790_00039 - 0.063 11.9 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pNC_008790_00039 - 0.064 13.6 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 pNC_008790_00039 - 0.084 12.8 0.3 0.22 11.4 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding MobB PF03205.14 pNC_008790_00039 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 pNC_008790_00039 - 0.11 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NTPase cobW PF02492.19 pNC_008790_00039 - 0.15 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pNC_008790_00039 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pNC_008790_00039 - 0.3 11.6 3.1 0.31 11.5 1.4 1.8 1 1 1 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 pNC_008790_00040 - 1e-104 351.0 0.1 1.5e-104 350.4 0.1 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pNC_008790_00040 - 9.3e-25 87.0 0.0 2.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pNC_008790_00040 - 1.9e-14 53.4 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Yos9_DD PF17880.1 pNC_008790_00040 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Yos9 dimerzation domain Cag12 PF13117.6 pNC_008790_00041 - 4.8e-17 62.3 0.3 6e-17 61.9 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 ERCC4 PF02732.15 pNC_008790_00041 - 0.052 13.7 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain DUF2689 PF10894.8 pNC_008790_00041 - 0.075 12.8 0.3 0.22 11.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF2706 PF10913.8 pNC_008790_00041 - 3.8 7.4 6.0 4.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2706) TrbM PF07424.11 pNC_008790_00042 - 1.3e-35 122.6 1.7 1.8e-35 122.2 1.7 1.2 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pNC_008790_00043 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 PRELI-like family Prismane PF03063.20 pNC_008790_00043 - 0.089 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Rsd_AlgQ PF04353.13 pNC_008790_00043 - 0.93 9.4 6.6 0.26 11.2 2.1 2.3 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Redoxin PF08534.10 pNC_008790_00045 - 0.054 13.2 0.9 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Redoxin Topoisom_bac PF01131.20 pNC_008790_00046 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pNC_008790_00046 - 5.6e-12 45.8 2.3 1e-11 44.9 0.0 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pNC_008790_00046 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pNC_008790_00046 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pNC_008790_00046 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pNC_008790_00046 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pNC_008790_00046 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pNC_008790_00046 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pNC_008790_00046 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pNC_008790_00046 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pNC_008790_00046 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pNC_008790_00046 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pNC_008790_00046 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pNC_008790_00046 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pNC_008790_00046 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pNC_008790_00046 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pNC_008790_00046 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pNC_008790_00047 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pNC_008790_00047 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain GTP_EFTU PF00009.27 pNC_008790_00049 - 5.4e-59 199.0 0.3 7.6e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pNC_008790_00049 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pNC_008790_00049 - 9.4e-17 60.8 0.0 2.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pNC_008790_00049 - 1.3e-12 47.6 0.1 3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pNC_008790_00049 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pNC_008790_00049 - 0.00029 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pNC_008790_00049 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Septin PF00735.18 pNC_008790_00049 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pNC_008790_00049 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 pNC_008790_00049 - 0.16 11.5 0.2 0.65 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF5442 PF17514.2 pNC_008790_00050 - 0.075 13.2 0.4 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5442) W2 PF02020.18 pNC_022355_00001 - 0.04 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon VirE_N PF08800.10 pNC_022355_00001 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 VirE N-terminal domain Lip_prot_lig_C PF10437.9 pNC_022355_00002 - 0.047 13.7 4.2 0.33 11.0 2.2 2.5 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus CtsR_C PF17727.1 pNC_022355_00002 - 0.048 13.8 0.1 5.1 7.3 0.0 2.4 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain DHHC PF01529.20 pNC_022355_00004 - 4.1 7.5 13.1 13 5.9 13.1 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4133 PF13571.6 pNC_022355_00004 - 5.6 7.4 7.4 7.5 7.0 6.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4133) DHHC PF01529.20 pNC_022355_00006 - 0.033 14.3 6.3 0.039 14.0 6.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase T4SS_CagC PF16943.5 pNC_022355_00006 - 0.046 13.9 0.2 0.056 13.6 0.2 1.1 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF4044 PF13253.6 pNC_022355_00008 - 0.035 13.6 0.8 0.062 12.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Claudin_2 PF13903.6 pNC_022355_00008 - 0.065 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2070 PF09843.9 pNC_022355_00008 - 0.072 11.4 1.1 0.11 10.8 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF443 PF04276.12 pNC_022355_00008 - 9.1 6.0 13.6 0.15 11.9 6.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Papo_T_antigen PF02380.15 pNC_022355_00009 - 0.00045 20.3 1.7 0.00056 20.0 1.7 1.4 1 0 0 1 1 1 1 T-antigen specific domain DUF1272 PF06906.11 pNC_022355_00009 - 0.013 15.5 4.2 0.023 14.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) adh_short PF00106.25 pNC_022355_00010 - 0.034 13.6 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Mur_ligase_C PF02875.21 pNC_022355_00010 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RHH_7 PF16777.5 pNC_022355_00011 - 2.1e-07 31.2 1.1 2.4e-07 31.1 1.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator, RHH-like, CopG BtrH_N PF14399.6 pNC_022355_00011 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SNF2_N PF00176.23 pNC_022355_00012 - 3.7e-16 58.8 2.9 4.5e-16 58.5 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.15 pNC_022355_00012 - 7.5e-08 32.6 8.9 7.5e-08 32.6 8.9 4.4 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 pNC_022355_00012 - 9.7e-07 29.1 0.3 4.8e-05 23.7 0.0 3.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 pNC_022355_00012 - 9.5e-06 25.5 2.0 0.0012 18.7 0.4 3.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Eco57I PF07669.11 pNC_022355_00012 - 2.5e-05 24.7 0.7 0.00022 21.7 0.2 3.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase NYN PF01936.18 pNC_022355_00013 - 2.2e-10 41.2 0.3 4e-10 40.3 0.3 1.6 1 1 0 1 1 1 1 NYN domain PIN7 PF18475.1 pNC_022355_00013 - 0.045 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PIN domain DUF1474 PF07342.11 pNC_022355_00013 - 0.054 14.0 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Acetyltransf_7 PF13508.7 pNC_022355_00014 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 pNC_022355_00014 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-F_leu_zip PF10473.9 pNC_022355_00014 - 0.0052 16.8 0.3 0.0082 16.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHM7_cyt PF14703.6 pNC_022355_00014 - 0.095 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Acetyltransf_10 PF13673.7 pNC_022355_00014 - 0.12 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc24 PF08286.11 pNC_022355_00014 - 0.39 11.0 3.2 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3913 PF13052.6 pNC_022355_00015 - 0.046 14.0 0.3 0.076 13.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3913) Relaxase PF03432.14 pNC_022355_00016 - 4.7e-10 39.5 7.4 4.7e-10 39.5 7.4 2.4 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain HTH_46 PF15977.5 pNC_022355_00017 - 0.00015 21.7 6.3 0.07 13.2 0.8 3.0 2 1 1 3 3 3 2 Winged helix-turn-helix DNA binding Spore_III_AB PF09548.10 pNC_022355_00017 - 0.046 13.8 2.1 0.063 13.4 1.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) NLRC4_HD PF17889.1 pNC_022355_00017 - 0.18 12.1 5.5 0.98 9.8 1.8 2.2 1 1 1 2 2 2 0 NLRC4 helical domain U3_assoc_6 PF08640.11 pNC_022355_00017 - 0.41 10.7 8.1 1 9.4 0.3 3.1 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DndE PF08870.11 pNC_022355_00017 - 0.42 10.9 6.2 0.54 10.5 1.0 2.6 2 1 0 2 2 2 0 DNA sulphur modification protein DndE CdvA PF18822.1 pNC_022355_00018 - 1.1 9.1 11.3 0.26 11.1 5.3 2.4 2 1 0 2 2 2 0 CdvA-like coiled-coil domain ESP PF16590.5 pNC_022355_00018 - 1.4 9.3 6.9 0.31 11.3 1.2 2.1 1 1 1 2 2 2 0 Exocrine gland-secreting peptide DUF3671 PF12420.8 pNC_022355_00018 - 1.7 8.7 15.5 0.15 12.1 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function Ribonuc_2-5A PF06479.12 pNC_022355_00022 - 0.065 13.4 5.2 0.2 11.9 5.2 1.9 1 1 0 1 1 1 0 Ribonuclease 2-5A DUF5311 PF17238.2 pNC_022355_00022 - 0.065 13.1 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Toprim_3 PF13362.6 pNC_022355_00023 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Paz_1 PF18349.1 pNC_022355_00023 - 0.09 12.7 0.3 0.33 10.9 0.3 2.0 1 0 0 1 1 1 0 PAZ domain Toprim_4 PF13662.6 pNC_022355_00023 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Toprim domain 5_3_exonuc PF01367.20 pNC_022355_00023 - 0.19 12.3 4.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF4223 PF13978.6 pNC_022355_00024 - 0.007 16.3 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) nec1 PF10379.9 pNC_022355_00024 - 0.067 12.7 0.0 0.099 12.1 0.0 1.2 1 1 0 1 1 1 0 Virulence protein nec1 Sdh_cyt PF01127.22 pNC_022355_00025 - 0.0011 19.0 0.6 0.0013 18.8 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2206 PF09971.9 pNC_022355_00025 - 0.031 13.0 4.0 0.033 13.0 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF2633 PF11119.8 pNC_022355_00025 - 0.97 9.4 4.2 2 8.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HicB_lk_antitox PF15919.5 pNC_022355_00027 - 6.3e-09 36.0 0.0 6.6e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system HicA_toxin PF07927.12 pNC_022355_00028 - 7.7e-12 45.1 0.3 9.4e-12 44.8 0.3 1.1 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, AAA_25 PF13481.6 pNC_022355_00029 - 5.3e-15 55.5 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pNC_022355_00029 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pNC_022355_00029 - 0.0023 17.7 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pNC_022355_00029 - 0.0087 15.4 0.0 0.074 12.4 0.0 2.4 2 1 0 2 2 2 1 KaiC AAA PF00004.29 pNC_022355_00029 - 0.014 15.8 0.2 0.33 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pNC_022355_00029 - 0.16 12.0 1.8 0.82 9.7 1.8 2.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApoC-I PF04691.12 pNC_022355_00029 - 0.38 10.7 3.0 5.1 7.1 0.0 3.6 3 2 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Resolvase PF00239.21 pNC_022355_00030 - 4.2e-34 117.7 0.8 5.7e-34 117.3 0.8 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_38 PF13936.6 pNC_022355_00030 - 0.034 13.9 0.9 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Mga PF08280.11 pNC_022355_00030 - 0.036 14.1 4.2 0.26 11.4 0.7 2.8 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain CRISPR_Cas2 PF09827.9 pNC_022355_00031 - 0.00073 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 CRISPR associated protein Cas2 TrbC PF04956.13 pNC_022355_00033 - 1.8e-14 53.8 7.8 1.9e-14 53.7 7.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DUF2062 PF09835.9 pNC_022355_00033 - 0.055 13.3 4.1 0.062 13.2 3.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CagE_TrbE_VirB PF03135.14 pNC_022355_00034 - 3.1e-51 174.4 0.4 7.1e-51 173.2 0.4 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pNC_022355_00034 - 3.6e-21 75.2 0.8 6.2e-21 74.4 0.8 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pNC_022355_00035 - 8.6e-29 99.9 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) SRA PF18491.1 pNC_022355_00035 - 0.066 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 SET and RING associated domain DUF2250 PF10007.9 pNC_022355_00035 - 0.13 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PBECR2 PF18810.1 pNC_022355_00036 - 0.062 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 SSB PF00436.25 pNC_022355_00037 - 2.3e-25 88.6 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family IF2_N PF04760.15 pNC_022355_00038 - 0.00029 20.6 7.3 0.00049 19.9 2.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FliG_N PF14842.6 pNC_022355_00038 - 0.018 15.6 1.1 0.021 15.3 1.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain HTH_16 PF12645.7 pNC_022355_00038 - 0.041 13.9 2.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 pNC_022355_00038 - 0.088 13.6 0.3 2.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor T4SS PF07996.11 pNC_022355_00039 - 1.7e-28 100.4 13.1 2.3e-28 99.9 13.1 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins DUF3045 PF11243.8 pNC_022355_00039 - 0.0035 17.5 0.5 0.021 15.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3045) VWA_2 PF13519.6 pNC_022355_00039 - 0.018 15.7 0.8 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain AATF-Che1 PF13339.6 pNC_022355_00039 - 0.48 11.1 11.5 0.4 11.4 4.6 2.5 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor TrbL PF04610.14 pNC_022355_00040 - 2.1e-30 106.1 33.3 2.1e-30 106.1 33.3 1.6 2 0 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein T_cell_tran_alt PF15128.6 pNC_022355_00040 - 0.069 13.0 1.0 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3606 PF12244.8 pNC_022355_00040 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AIM3 PF17096.5 pNC_022355_00040 - 0.3 12.1 6.0 0.57 11.1 6.0 1.4 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 La_HTH_kDCL PF18177.1 pNC_022355_00041 - 0.2 12.0 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain VirB8 PF04335.13 pNC_022355_00042 - 1.6e-52 178.5 0.5 1.8e-52 178.3 0.5 1.0 1 0 0 1 1 1 1 VirB8 protein OppC_N PF12911.7 pNC_022355_00042 - 0.045 13.7 0.5 0.088 12.8 0.5 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CagX PF03524.15 pNC_022355_00043 - 9.6e-56 188.8 1.9 1.5e-55 188.2 1.9 1.3 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pNC_022355_00044 - 2.4e-47 161.2 0.0 2.4e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein RE_HaeIII PF09556.10 pNC_022355_00044 - 0.043 12.9 0.1 0.067 12.3 0.1 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease T2SSE PF00437.20 pNC_022355_00045 - 6.9e-55 186.0 0.0 8.1e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 pNC_022355_00045 - 7.2e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pNC_022355_00045 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pNC_022355_00045 - 0.00028 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 pNC_022355_00045 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 pNC_022355_00045 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_24 PF13479.6 pNC_022355_00045 - 0.0026 17.5 0.2 0.0054 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 pNC_022355_00045 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 pNC_022355_00045 - 0.0055 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.12 pNC_022355_00045 - 0.0073 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Septin PF00735.18 pNC_022355_00045 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin ATPase_2 PF01637.18 pNC_022355_00045 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 pNC_022355_00045 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 pNC_022355_00045 - 0.021 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 pNC_022355_00045 - 0.023 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 pNC_022355_00045 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 pNC_022355_00045 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 pNC_022355_00045 - 0.031 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 pNC_022355_00045 - 0.035 14.2 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 pNC_022355_00045 - 0.04 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 pNC_022355_00045 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 pNC_022355_00045 - 0.046 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 pNC_022355_00045 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GvpD PF07088.11 pNC_022355_00045 - 0.065 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_16 PF13191.6 pNC_022355_00045 - 0.075 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 pNC_022355_00045 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 pNC_022355_00045 - 0.089 12.7 0.4 0.22 11.5 0.3 1.7 1 1 0 1 1 1 0 Microtubule binding NTPase_1 PF03266.15 pNC_022355_00045 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 pNC_022355_00045 - 0.12 13.0 0.0 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 pNC_022355_00045 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 pNC_022355_00045 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 pNC_022355_00045 - 0.38 11.2 4.1 0.38 11.2 1.3 2.1 1 1 1 2 2 2 0 AAA domain Carbam_trans_N PF02543.15 pNC_022355_00046 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus T4SS-DNA_transf PF02534.14 pNC_022355_00047 - 8.3e-104 348.0 0.1 1.1e-103 347.5 0.1 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pNC_022355_00047 - 3.5e-24 85.2 0.0 6.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pNC_022355_00047 - 3.2e-15 55.9 0.0 5.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Phage_holin_3_6 PF07332.11 pNC_022355_00047 - 0.17 11.9 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ECF_trnsprt PF12822.7 pNC_022355_00047 - 1.2 9.2 8.3 2 8.5 8.3 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Cag12 PF13117.6 pNC_022355_00048 - 1.4e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 DUF2689 PF10894.8 pNC_022355_00048 - 0.06 13.1 0.4 0.16 11.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) TrbM PF07424.11 pNC_022355_00049 - 4.1e-38 130.8 2.0 5.3e-38 130.4 2.0 1.1 1 0 0 1 1 1 1 TrbM PRELI PF04707.14 pNC_022355_00050 - 0.044 13.6 0.3 0.044 13.6 0.3 1.9 2 0 0 2 2 2 0 PRELI-like family TACC_C PF05010.14 pNC_022355_00050 - 0.92 9.3 9.3 2.4 7.9 8.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CdhD PF03599.16 pNC_022355_00051 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Pox_RNA_pol PF03293.14 pNC_022355_00051 - 0.012 15.3 0.9 0.027 14.2 0.9 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Redoxin PF08534.10 pNC_022355_00051 - 0.059 13.1 0.5 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 Redoxin DUF1461 PF07314.11 pNC_022355_00052 - 0.13 12.2 1.5 0.2 11.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Topoisom_bac PF01131.20 pNC_022355_00053 - 8e-97 324.9 8.1 1.1e-96 324.4 8.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pNC_022355_00053 - 6.3e-12 45.6 2.6 9.7e-12 45.0 0.1 2.7 2 1 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pNC_022355_00053 - 5.6e-08 32.4 15.3 1.7e-05 24.5 5.5 2.8 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pNC_022355_00053 - 1e-05 25.7 2.3 0.043 14.1 0.0 2.7 3 0 0 3 3 3 2 zinc-ribbon Zn-ribbon_8 PF09723.10 pNC_022355_00053 - 0.012 15.7 1.3 5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 pNC_022355_00053 - 0.028 14.9 8.1 1.2 9.7 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger double domain FLYWCH PF04500.16 pNC_022355_00053 - 0.039 14.1 3.0 1.3 9.2 1.0 2.6 2 0 0 2 2 2 0 FLYWCH zinc finger domain zf-C2H2_4 PF13894.6 pNC_022355_00053 - 0.056 14.3 2.8 7.9 7.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 pNC_022355_00053 - 0.087 12.3 2.7 3.4 7.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_8 PF13833.6 pNC_022355_00053 - 0.094 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair zf-LITAF-like PF10601.9 pNC_022355_00053 - 0.095 13.0 4.5 1 9.6 3.7 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain HTH_34 PF13601.6 pNC_022355_00053 - 0.46 10.7 3.3 0.85 9.8 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain zf_UBZ PF18439.1 pNC_022355_00053 - 0.54 9.9 3.0 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 pNC_022355_00053 - 0.64 10.0 3.8 4.5 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 pNC_022355_00053 - 0.75 9.9 3.8 4.3 7.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PADR1 PF08063.12 pNC_022355_00053 - 1.6 8.6 5.5 18 5.2 0.3 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-C2HC_2 PF13913.6 pNC_022355_00053 - 8.4 6.4 6.5 11 6.0 0.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PcfJ PF14284.6 pNC_022355_00054 - 5.4e-05 23.1 2.2 0.00013 21.8 2.2 1.7 1 0 0 1 1 1 1 PcfJ-like protein Intein_splicing PF14890.6 pNC_022355_00054 - 0.023 14.7 3.9 0.17 11.9 3.9 2.5 1 1 0 1 1 1 0 Intein splicing domain APH PF01636.23 pNC_022355_00056 - 5.8e-22 78.8 0.0 7.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 pNC_022355_00056 - 2.1e-06 27.5 0.1 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 pNC_022355_00056 - 0.00034 19.6 0.1 0.00056 18.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 pNC_022355_00056 - 0.00076 19.1 0.2 0.0021 17.7 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 pNC_022355_00056 - 0.0095 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase GTP_EFTU PF00009.27 pNC_022355_00057 - 5.6e-59 198.9 0.3 7.8e-59 198.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 pNC_022355_00057 - 3.5e-23 81.7 0.0 9.7e-23 80.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 pNC_022355_00057 - 1.3e-16 60.4 0.0 3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 pNC_022355_00057 - 2.1e-12 46.9 0.1 5e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 pNC_022355_00057 - 2e-06 27.9 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 pNC_022355_00057 - 0.00055 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 pNC_022355_00057 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Septin PF00735.18 pNC_022355_00057 - 0.021 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 pNC_022355_00057 - 0.05 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CPSF_A PF03178.15 pNC_022355_00059 - 0.034 13.4 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 CPSF A subunit region ATPase PF06745.13 pNC_022355_00059 - 0.048 13.0 0.2 0.049 13.0 0.2 1.1 1 0 0 1 1 1 0 KaiC TipAS PF07739.13 pNC_022355_00059 - 0.061 13.9 1.5 1.2 9.7 1.9 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain 3HCDH PF00725.22 pNC_022355_00059 - 0.091 13.4 0.2 0.14 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4942 PF13708.6 pNC_022355_00059 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) PNP_UDP_1 PF01048.20 pNC_022355_00060 - 7.6e-29 100.6 0.0 8.7e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4111 PF13427.6 pNC_022355_00061 - 3.1e-17 62.6 0.0 1.8e-16 60.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 pNC_022355_00061 - 8.7e-10 38.6 0.0 3.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 pNC_022355_00061 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 pNC_022355_00061 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain DUF4111 PF13427.6 pNC_022355_00062 - 0.0023 18.0 0.0 0.0027 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) AAA_18 PF13238.6 pNC_022355_00063 - 5.7e-14 52.8 0.0 7.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 pNC_022355_00063 - 3e-09 37.0 0.0 5.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 pNC_022355_00063 - 6.4e-09 36.1 0.0 9.4e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 pNC_022355_00063 - 1.5e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.29 pNC_022355_00063 - 8.7e-06 26.2 0.2 8.1e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 pNC_022355_00063 - 0.0001 22.6 0.1 0.0004 20.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 pNC_022355_00063 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 pNC_022355_00063 - 0.00034 20.9 0.0 0.00099 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 pNC_022355_00063 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 pNC_022355_00063 - 0.0016 18.2 0.1 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 pNC_022355_00063 - 0.0024 18.2 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pNC_022355_00063 - 0.0031 18.0 0.1 0.0041 17.6 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 pNC_022355_00063 - 0.0045 17.4 0.0 0.0092 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 pNC_022355_00063 - 0.0048 16.4 0.0 0.0095 15.4 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.9 pNC_022355_00063 - 0.005 16.1 0.2 0.0077 15.5 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 pNC_022355_00063 - 0.0076 16.2 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 pNC_022355_00063 - 0.0092 15.7 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 pNC_022355_00063 - 0.0096 15.7 0.3 0.0097 15.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 pNC_022355_00063 - 0.0099 15.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 T2SSE PF00437.20 pNC_022355_00063 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 pNC_022355_00063 - 0.011 15.1 1.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 pNC_022355_00063 - 0.012 15.5 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 pNC_022355_00063 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 pNC_022355_00063 - 0.021 14.7 1.0 0.049 13.5 0.3 1.8 2 0 0 2 2 2 0 NTPase dNK PF01712.19 pNC_022355_00063 - 0.034 14.0 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 pNC_022355_00063 - 0.035 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 pNC_022355_00063 - 0.035 13.3 0.2 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 pNC_022355_00063 - 0.039 13.8 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 pNC_022355_00063 - 0.06 12.7 0.4 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MKT1_N PF12247.8 pNC_022355_00063 - 0.069 13.5 0.0 0.28 11.6 0.0 2.1 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication AAA_11 PF13086.6 pNC_022355_00063 - 0.073 12.8 1.5 0.12 12.1 1.5 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 pNC_022355_00063 - 0.076 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 pNC_022355_00063 - 0.089 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 pNC_022355_00063 - 0.1 12.5 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 pNC_022355_00063 - 0.14 11.8 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 pNC_022355_00063 - 0.18 11.3 0.7 0.28 10.7 0.1 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 pNC_022355_00063 - 0.2 11.8 1.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Cytidylate kinase-like family APH PF01636.23 pNC_022355_00064 - 8.7e-24 84.8 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 pNC_022355_00064 - 2.9e-06 26.7 0.1 1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 pNC_022355_00064 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 pNC_022355_00064 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase TMEM95 PF15203.6 pNC_022355_00064 - 0.044 13.4 0.4 0.072 12.7 0.4 1.3 1 0 0 1 1 1 0 TMEM95 family EcKinase PF02958.20 pNC_022355_00064 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_C15 PF01470.17 pNC_022355_00065 - 2.2e-51 174.9 0.1 2.4e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase Adenyl_transf PF04439.12 pNC_022355_00066 - 4.8e-56 189.9 1.4 5.9e-56 189.6 1.4 1.0 1 0 0 1 1 1 1 Streptomycin adenylyltransferase Acetyltransf_1 PF00583.25 pNC_022355_00067 - 3.8e-20 72.3 0.1 5.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 pNC_022355_00067 - 1.2e-13 51.2 0.1 2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 pNC_022355_00067 - 2.7e-12 46.7 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 pNC_022355_00067 - 1.1e-09 38.6 1.1 1.3e-09 38.3 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 pNC_022355_00067 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 pNC_022355_00067 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 pNC_022355_00067 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 pNC_022355_00067 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein APH PF01636.23 pNC_022355_00068 - 2.8e-26 92.9 0.0 3.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 pNC_022355_00068 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 pNC_022355_00068 - 0.019 14.5 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family zf-HC2 PF13490.6 pNC_022355_00069 - 3.2e-06 27.3 2.7 6.9e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger Glyco_hydro_100 PF12899.7 pNC_022355_00069 - 0.11 11.1 0.0 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 pNC_022355_00069 - 0.15 12.4 0.7 0.21 11.9 0.7 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 pNC_022355_00070 - 2.5e-07 30.3 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 pNC_022355_00070 - 3.8e-06 26.3 0.0 6.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 pNC_022355_00070 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Reticulon PF02453.17 pNZ_AAFJ01000010_00004 - 0.011 15.7 3.4 0.011 15.7 3.4 1.2 1 0 0 1 1 1 0 Reticulon TK PF00265.18 pNZ_AAFJ01000010_00005 - 7e-20 71.6 1.2 1.6e-19 70.5 1.2 1.6 1 1 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 pNZ_AAFJ01000010_00005 - 0.003 17.6 0.3 0.004 17.2 0.3 1.2 1 0 0 1 1 1 1 AAA domain Terminase_6 PF03237.15 pNZ_AAFJ01000010_00005 - 0.0088 15.7 0.4 0.03 14.0 0.4 1.9 1 1 0 1 1 1 1 Terminase-like family FcoT PF10862.8 pNZ_AAFJ01000010_00006 - 0.031 13.9 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 FcoT-like thioesterase domain ECH_2 PF16113.5 pNZ_AAFJ01000010_00006 - 0.044 13.3 0.5 0.045 13.3 0.5 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase EF-hand_7 PF13499.6 pNZ_AAFJ01000010_00006 - 0.068 13.6 0.2 2.6 8.5 0.2 2.1 1 1 0 1 1 1 0 EF-hand domain pair DUF3973 PF13119.6 pNZ_AAFJ01000010_00007 - 0.088 12.9 2.7 0.35 11.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Toprim_2 PF13155.6 pNZ_AAFJ01000010_00010 - 2.2e-11 44.0 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.6 pNZ_AAFJ01000010_00010 - 4.2e-05 23.8 0.0 8.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.20 pNZ_AAFJ01000010_00010 - 0.0061 16.4 0.1 0.037 13.8 0.1 2.2 2 0 0 2 2 2 1 CHC2 zinc finger DUF3854 PF12965.7 pNZ_AAFJ01000010_00010 - 0.094 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) CSN8_PSD8_EIF3K PF10075.9 pNZ_AAFJ01000010_00011 - 0.31 11.0 4.2 0.29 11.1 0.8 2.2 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family Peptidase_C39 PF03412.15 pNZ_AAFJ01000010_00015 - 2.5e-17 62.9 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 pNZ_AAFJ01000010_00015 - 3e-05 24.0 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Phage_integrase PF00589.22 pNZ_AAFJ01000010_00017 - 2.8e-20 72.8 2.1 4.4e-20 72.2 2.1 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 pNZ_AAFJ01000010_00017 - 5.5e-05 23.4 2.7 0.081 13.2 0.1 3.1 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 pNZ_AAFJ01000010_00017 - 0.00022 21.5 8.0 0.00022 21.5 8.0 2.7 2 2 0 2 2 2 1 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 pNZ_AAFJ01000010_00017 - 0.0026 18.2 5.5 0.0026 18.2 5.5 2.5 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 pNZ_AAFJ01000010_00017 - 0.0035 17.5 0.4 0.0067 16.5 0.4 1.5 1 0 0 1 1 1 1 Integrase Phage_int_SAM_6 PF18644.1 pNZ_AAFJ01000010_00017 - 3.7 7.6 16.4 0.77 9.8 0.9 3.2 3 1 1 4 4 4 0 Phage integrase SAM-like domain HMG-CoA_red PF00368.18 pNZ_AAFJ01000010_00018 - 0.083 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase WGR PF05406.15 pNZ_AAFJ01000010_00019 - 0.00012 22.0 0.3 0.00014 21.8 0.3 1.1 1 0 0 1 1 1 1 WGR domain Latarcin PF10279.9 pNZ_AAFJ01000010_00019 - 0.01 16.2 0.1 0.015 15.7 0.1 1.2 1 0 0 1 1 1 0 Latarcin precursor Tantalus PF15386.6 pNZ_AAFJ01000010_00019 - 0.047 13.8 0.1 0.047 13.8 0.1 1.9 1 1 1 2 2 2 0 Drosophila Tantalus-like PPR_2 PF13041.6 pNZ_AAFJ01000010_00019 - 0.14 12.4 0.9 0.23 11.7 0.9 1.4 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.20 pNZ_AAFJ01000010_00019 - 0.23 11.8 1.6 0.31 11.4 0.7 1.6 2 0 0 2 2 2 0 PPR repeat HD PF01966.22 pNZ_AAFJ01000010_00021 - 1.8e-10 41.1 0.9 3.6e-10 40.1 0.9 1.6 1 0 0 1 1 1 1 HD domain HD_6 PF18019.1 pNZ_AAFJ01000010_00021 - 0.029 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 HD domain TrwB_AAD_bind PF10412.9 pNZ_AAFJ01000010_00022 - 4e-17 62.2 0.0 6.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain T4SS-DNA_transf PF02534.14 pNZ_AAFJ01000010_00022 - 2e-15 56.6 0.5 2.7e-15 56.2 0.5 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pNZ_AAFJ01000010_00022 - 1.3e-10 41.3 0.1 2.7e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG DUF87 PF01935.17 pNZ_AAFJ01000010_00022 - 1.2e-05 25.6 0.5 2.9e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_10 PF12846.7 pNZ_AAFJ01000010_00022 - 1.3e-05 24.3 0.3 0.012 14.5 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain DUF853 PF05872.12 pNZ_AAFJ01000010_00022 - 0.0034 16.0 0.0 0.0076 14.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 pNZ_AAFJ01000010_00022 - 0.007 16.6 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 pNZ_AAFJ01000010_00022 - 0.016 15.6 0.0 0.078 13.4 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain ATPase_2 PF01637.18 pNZ_AAFJ01000010_00022 - 0.018 14.9 0.1 0.064 13.2 0.1 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 pNZ_AAFJ01000010_00022 - 0.034 14.7 0.1 0.097 13.2 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 pNZ_AAFJ01000010_00022 - 0.042 13.1 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF1548 PF07579.11 pNZ_AAFJ01000010_00022 - 0.11 12.8 1.9 0.44 10.9 0.2 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) FtsK_SpoIIIE PF01580.18 pNZ_AAFJ01000010_00022 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArlS_N PF18719.1 pNZ_AAFJ01000010_00022 - 0.91 9.7 4.0 2.1 8.6 0.2 2.5 2 1 0 2 2 2 0 ArlS sensor domain OSTMP1 PF09777.9 pNZ_AAFJ01000010_00023 - 1.2 8.5 3.2 6.1 6.2 0.3 2.3 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor MnmE_helical PF12631.7 pNZ_AAFJ01000010_00024 - 0.44 10.7 1.7 0.7 10.0 1.7 1.5 1 1 0 1 1 1 0 MnmE helical domain HTH_3 PF01381.22 pNZ_AAFJ01000010_00025 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pNZ_AAFJ01000010_00025 - 1.2e-08 34.8 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 pNZ_AAFJ01000010_00025 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain APG12 PF04110.13 pNZ_AAFJ01000010_00025 - 0.1 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 AAA_19 PF13245.6 pNZ_AAFJ01000010_00026 - 6.3e-14 52.5 0.2 4.6e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 pNZ_AAFJ01000010_00026 - 6.5e-12 45.6 17.8 8.3e-10 38.7 1.7 4.0 1 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 pNZ_AAFJ01000010_00026 - 6.1e-11 42.5 0.3 2.8e-05 24.0 0.1 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 pNZ_AAFJ01000010_00026 - 4.3e-10 39.5 16.6 4.7e-10 39.4 12.7 2.5 1 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 pNZ_AAFJ01000010_00026 - 6e-09 35.6 0.0 4.8e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 pNZ_AAFJ01000010_00026 - 8.1e-06 25.7 0.0 0.0045 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 pNZ_AAFJ01000010_00026 - 0.00049 19.6 0.2 0.47 9.9 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein DUF2075 PF09848.9 pNZ_AAFJ01000010_00026 - 0.02 14.2 0.3 3.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Peptidase_M6 PF05547.11 pNZ_AAFJ01000010_00026 - 0.025 12.9 0.1 0.037 12.4 0.1 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Helicase_RecD PF05127.14 pNZ_AAFJ01000010_00026 - 0.04 13.8 0.7 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Helicase AAA_11 PF13086.6 pNZ_AAFJ01000010_00026 - 0.11 12.3 0.5 19 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 pNZ_AAFJ01000010_00026 - 0.34 10.9 8.2 0.065 13.2 1.8 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Thioredoxin_7 PF13899.6 pNZ_AAFJ01000010_00027 - 4.1e-05 23.7 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 pNZ_AAFJ01000010_00027 - 0.00038 20.9 0.4 0.0011 19.4 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 pNZ_AAFJ01000010_00027 - 0.047 13.6 0.2 0.055 13.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF255 Redoxin PF08534.10 pNZ_AAFJ01000010_00027 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin TrbC_Ftype PF09673.10 pNZ_AAFJ01000010_00028 - 2e-16 60.0 0.0 3.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein DUF1694 PF07997.11 pNZ_AAFJ01000010_00028 - 0.0015 18.6 0.5 0.0085 16.2 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1694) DUF3502 PF12010.8 pNZ_AAFJ01000010_00028 - 0.028 15.0 2.0 0.028 15.0 2.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3502) Thioredoxin PF00085.20 pNZ_AAFJ01000010_00028 - 0.039 14.0 0.3 0.11 12.5 0.3 1.8 1 0 0 1 1 1 0 Thioredoxin TraU PF06834.11 pNZ_AAFJ01000010_00029 - 9.6e-97 323.9 0.0 1.1e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 TraU protein RhoGAP PF00620.27 pNZ_AAFJ01000010_00031 - 0.0012 18.7 1.6 0.0012 18.7 1.6 1.7 2 0 0 2 2 2 1 RhoGAP domain DUF4252 PF14060.6 pNZ_AAFJ01000010_00031 - 0.32 10.9 8.4 0.086 12.7 4.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4252) ALP_N PF17989.1 pNZ_AAFJ01000010_00034 - 7.7e-13 48.9 0.1 1.3e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 Actin like proteins N terminal domain FtsA PF14450.6 pNZ_AAFJ01000010_00034 - 0.00018 21.9 0.2 0.099 13.1 0.0 2.4 2 1 0 2 2 2 2 Cell division protein FtsA DUF4879 PF16219.5 pNZ_AAFJ01000010_00035 - 0.0012 19.0 0.2 0.0013 18.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4879) YopX PF09643.10 pNZ_AAFJ01000010_00036 - 3e-12 46.7 2.7 2.3e-11 43.9 1.0 2.2 1 1 1 2 2 2 2 YopX protein DUF4600 PF15372.6 pNZ_AAFJ01000010_00037 - 0.0093 16.4 0.2 0.011 16.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) TMF_TATA_bd PF12325.8 pNZ_AAFJ01000010_00037 - 0.023 14.9 0.1 0.035 14.3 0.1 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YopX PF09643.10 pNZ_AAFJ01000010_00038 - 2.8e-08 33.9 0.6 4e-08 33.4 0.6 1.3 1 1 0 1 1 1 1 YopX protein HTH_17 PF12728.7 pNZ_AAFJ01000010_00041 - 2.5e-07 30.7 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 pNZ_AAFJ01000010_00041 - 1.6e-05 24.8 0.0 0.067 13.3 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix HTH_19 PF12844.7 pNZ_AAFJ01000010_00041 - 6.8e-05 22.8 0.5 0.0032 17.4 0.2 2.7 1 1 1 2 2 2 2 Helix-turn-helix domain MerR PF00376.23 pNZ_AAFJ01000010_00041 - 0.00015 21.4 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 2 MerR family regulatory protein HTH_26 PF13443.6 pNZ_AAFJ01000010_00041 - 0.0011 19.4 0.1 0.26 11.8 0.1 2.6 2 1 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain Phage_CI_repr PF07022.13 pNZ_AAFJ01000010_00041 - 0.0014 18.7 0.0 0.0073 16.4 0.0 2.0 2 0 0 2 2 2 1 Bacteriophage CI repressor helix-turn-helix domain Terminase_5 PF06056.12 pNZ_AAFJ01000010_00041 - 0.0024 17.7 0.2 0.037 13.9 0.0 2.6 2 1 1 3 3 3 1 Putative ATPase subunit of terminase (gpP-like) HTH_Crp_2 PF13545.6 pNZ_AAFJ01000010_00041 - 0.0028 17.6 0.0 0.053 13.5 0.0 2.5 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 pNZ_AAFJ01000010_00041 - 0.0046 16.7 0.0 2.2 8.2 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain MerR_1 PF13411.6 pNZ_AAFJ01000010_00041 - 0.0086 16.2 0.0 1.1 9.4 0.0 2.6 2 1 0 2 2 2 1 MerR HTH family regulatory protein SL4P PF17618.2 pNZ_AAFJ01000010_00041 - 0.026 14.6 1.6 4.7 7.3 0.3 2.5 2 1 0 2 2 2 0 Uncharacterized Strongylid L4 protein Vps4_C PF09336.10 pNZ_AAFJ01000010_00041 - 0.036 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Phage_terminase PF10668.9 pNZ_AAFJ01000010_00041 - 0.054 13.5 0.1 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Phage terminase small subunit SNase PF00565.17 pNZ_AAFJ01000010_00042 - 5.7e-24 84.7 0.4 9.2e-24 84.0 0.4 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue O-antigen_lig PF13425.6 pNZ_AAFJ01000010_00042 - 0.022 13.6 4.2 0.027 13.3 4.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4065 PF13274.6 pNZ_AAFJ01000010_00043 - 0.001 19.9 0.8 0.0013 19.6 0.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4065) N6_N4_Mtase PF01555.18 pNZ_AAFJ01000010_00044 - 3.2e-15 56.5 7.5 1.5e-08 34.6 1.9 3.5 3 1 0 3 3 3 2 DNA methylase UPF0020 PF01170.18 pNZ_AAFJ01000010_00044 - 4.1e-06 26.6 0.0 0.051 13.3 0.0 2.6 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 pNZ_AAFJ01000010_00044 - 0.0038 16.9 0.0 0.5 10.0 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 AviRa PF11599.8 pNZ_AAFJ01000010_00044 - 0.021 14.3 0.6 0.12 11.8 0.0 2.3 3 0 0 3 3 3 0 RRNA methyltransferase AviRa Stork_head PF10264.9 pNZ_AAFJ01000010_00044 - 0.049 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain N6_N4_Mtase PF01555.18 pNZ_AAFJ01000010_00045 - 9.5e-26 90.9 0.2 2e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Methyltransf_25 PF13649.6 pNZ_AAFJ01000010_00045 - 2.4e-08 34.6 0.0 1.7e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 pNZ_AAFJ01000010_00045 - 3.1e-08 34.2 0.0 2.9e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 pNZ_AAFJ01000010_00045 - 6.3e-08 32.5 0.1 1.2e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 pNZ_AAFJ01000010_00045 - 2.1e-06 27.4 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 pNZ_AAFJ01000010_00045 - 4.7e-05 23.2 0.1 0.0016 18.1 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 pNZ_AAFJ01000010_00045 - 0.0002 21.0 0.1 0.00089 18.9 0.0 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 pNZ_AAFJ01000010_00045 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 pNZ_AAFJ01000010_00045 - 0.0058 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 pNZ_AAFJ01000010_00045 - 0.024 15.4 0.0 0.068 13.9 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 pNZ_AAFJ01000010_00045 - 0.027 14.3 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 pNZ_AAFJ01000010_00045 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1883 PF08980.10 pNZ_AAFJ01000010_00046 - 0.15 12.0 0.3 0.41 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) ParE_toxin PF05016.15 pNZ_AAFJ01000010_00047 - 3.8e-09 37.0 0.2 4.7e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 pNZ_AAFJ01000010_00047 - 0.0008 19.7 0.2 0.00099 19.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ IKKbetaNEMObind PF12179.8 pNZ_AAFJ01000010_00047 - 0.09 12.8 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain RHH_5 PF07878.11 pNZ_AAFJ01000010_00048 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 RHH_3 PF12651.7 pNZ_AAFJ01000010_00048 - 0.00048 20.0 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix domain HicB_lk_antitox PF15919.5 pNZ_AAFJ01000010_00048 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system CcdA PF07362.12 pNZ_AAFJ01000010_00048 - 0.025 15.0 0.1 0.034 14.6 0.1 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA PuR_N PF09182.10 pNZ_AAFJ01000010_00048 - 0.16 11.9 0.1 0.2 11.6 0.1 1.3 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal Bro-N PF02498.17 pNZ_AAFJ01000010_00049 - 1.6e-22 80.0 2.7 1.9e-22 79.8 0.0 2.2 2 1 0 2 2 2 1 BRO family, N-terminal domain HTH_3 PF01381.22 pNZ_AAFJ01000010_00049 - 2e-07 31.0 0.1 6.7e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pNZ_AAFJ01000010_00049 - 4.5e-07 29.8 0.1 4.5e-07 29.8 0.1 3.0 4 0 0 4 4 4 1 Helix-turn-helix domain ZapD PF07072.11 pNZ_AAFJ01000010_00049 - 0.00027 20.7 3.0 0.014 15.2 0.1 2.7 2 1 0 2 2 2 2 Cell division protein HTH_31 PF13560.6 pNZ_AAFJ01000010_00049 - 0.0048 17.2 0.0 0.0092 16.3 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain SLT PF01464.20 pNZ_AAFJ01000010_00050 - 3.1e-22 78.4 0.0 3.6e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 pNZ_AAFJ01000010_00050 - 0.017 15.6 0.2 0.035 14.6 0.2 1.6 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Lys PF00062.20 pNZ_AAFJ01000010_00050 - 0.07 13.4 0.1 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family UPF0146 PF03686.13 pNZ_AAFJ01000010_00050 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) YafQ_toxin PF15738.5 pNZ_AAFJ01000010_00052 - 9.3e-26 90.0 0.7 1.1e-25 89.8 0.7 1.0 1 0 0 1 1 1 1 Bacterial toxin of type II toxin-antitoxin system, YafQ ASL_C PF08328.11 pNZ_AAFJ01000010_00052 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DDE_Tnp_1_7 PF13843.6 pNZ_AAFJ01000010_00053 - 0.0083 15.5 1.0 0.009 15.3 1.0 1.2 1 0 0 1 1 1 1 Transposase IS4 LETM1 PF07766.13 pNZ_AAFJ01000010_00053 - 0.009 15.4 4.8 0.01 15.2 4.8 1.2 1 0 0 1 1 1 1 LETM1-like protein Baculo_p24 PF05073.12 pNZ_AAFJ01000010_00053 - 0.035 13.9 2.5 0.038 13.8 2.5 1.0 1 0 0 1 1 1 0 Baculovirus P24 capsid protein PIEZO PF15917.5 pNZ_AAFJ01000010_00053 - 0.073 12.5 5.7 0.084 12.3 5.7 1.1 1 0 0 1 1 1 0 Piezo DUF4446 PF14584.6 pNZ_AAFJ01000010_00053 - 1.3 9.0 6.0 1.6 8.7 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Oxidored_q3 PF00499.20 pNZ_AAFJ01000010_00054 - 0.0036 17.0 0.2 0.0052 16.5 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TctA PF01970.16 pNZ_AAFJ01000010_00054 - 0.016 14.0 0.6 0.022 13.5 0.6 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Carbpep_Y_N PF05388.11 pNZ_AAFJ01000010_00054 - 0.027 15.0 2.7 0.027 15.0 0.8 1.8 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Phage_holin_3_6 PF07332.11 pNZ_AAFJ01000010_00054 - 0.11 12.6 0.3 0.18 11.9 0.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RseC_MucC PF04246.12 pNZ_AAFJ01000010_00054 - 0.13 12.2 1.3 0.21 11.6 1.3 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 pNZ_AAFJ01000010_00054 - 0.27 10.0 7.3 0.35 9.6 7.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spore_YhaL PF14147.6 pNZ_AAFJ01000010_00054 - 4 7.2 5.2 1.7 8.4 0.6 2.5 2 1 0 2 2 2 0 Sporulation protein YhaL Bacillus_PapR PF05968.11 pNZ_AAFJ01000010_00055 - 0.022 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Bacillus PapR protein YtpI PF14007.6 pNZ_AAFJ01000010_00055 - 0.024 14.8 9.1 0.038 14.1 0.1 2.9 2 1 1 3 3 3 0 YtpI-like protein TraL PF07178.11 pNZ_AAFJ01000010_00056 - 3.1e-13 50.0 0.5 3.6e-13 49.8 0.5 1.1 1 0 0 1 1 1 1 TraL protein TraE PF05309.11 pNZ_AAFJ01000010_00057 - 1e-32 113.0 0.8 1.3e-32 112.7 0.8 1.0 1 0 0 1 1 1 1 TraE protein TraK PF06586.11 pNZ_AAFJ01000010_00058 - 8.9e-23 81.2 0.2 2.6e-22 79.7 0.2 1.6 1 1 0 1 1 1 1 TraK protein TrbI PF03743.14 pNZ_AAFJ01000010_00059 - 4.8e-35 121.1 1.5 8e-35 120.4 1.5 1.4 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein Cep57_CLD PF14073.6 pNZ_AAFJ01000010_00059 - 0.0019 18.2 4.7 0.0019 18.2 4.7 2.1 2 1 0 2 2 2 1 Centrosome localisation domain of Cep57 O-antigen_lig PF13425.6 pNZ_AAFJ01000010_00059 - 0.08 11.7 8.5 0.13 11.0 8.5 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YrzK PF17449.2 pNZ_AAFJ01000010_00059 - 0.35 11.2 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized YrzK-like YabA PF06156.13 pNZ_AAFJ01000010_00059 - 0.61 10.8 11.7 0.061 14.0 5.6 2.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF4481 PF14800.6 pNZ_AAFJ01000010_00059 - 9 5.7 6.3 1.5 8.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Thioredoxin_2 PF13098.6 pNZ_AAFJ01000010_00060 - 1.4e-15 57.6 0.2 3.5e-15 56.4 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain DsbC_N PF10411.9 pNZ_AAFJ01000010_00060 - 8.2e-10 38.0 0.1 1.5e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 pNZ_AAFJ01000010_00060 - 0.0014 18.8 4.8 0.39 10.9 0.3 2.4 1 1 1 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 pNZ_AAFJ01000010_00060 - 0.0033 17.6 0.1 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.6 pNZ_AAFJ01000010_00060 - 0.086 12.7 0.1 6 6.6 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 pNZ_AAFJ01000010_00060 - 0.1 12.9 1.3 0.39 11.1 0.7 2.2 2 1 0 2 2 2 0 Thioredoxin-like DUF393 PF04134.12 pNZ_AAFJ01000010_00060 - 0.14 13.5 0.0 0.33 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF393 SH3_3 PF08239.11 pNZ_AAFJ01000010_00061 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain TraV PF09676.10 pNZ_AAFJ01000010_00061 - 0.00078 20.4 1.2 0.00078 20.4 1.2 2.5 2 1 0 2 2 2 1 Type IV conjugative transfer system lipoprotein (TraV) DUF3410 PF11890.8 pNZ_AAFJ01000010_00061 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) SH3_3 PF08239.11 pNZ_AAFJ01000010_00062 - 0.00054 20.2 0.1 0.00093 19.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain PBP_dimer PF03717.15 pNZ_AAFJ01000010_00062 - 0.027 14.8 0.7 0.035 14.4 0.7 1.1 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Closter_coat PF01785.17 pNZ_AAFJ01000010_00062 - 0.064 12.5 0.2 0.088 12.1 0.2 1.1 1 0 0 1 1 1 0 Closterovirus coat protein TraC_F_IV PF11130.8 pNZ_AAFJ01000010_00064 - 5.7e-32 111.2 0.0 2.1e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 pNZ_AAFJ01000010_00064 - 1.6e-10 40.5 0.2 9.3e-10 38.0 0.2 2.0 1 1 0 1 1 1 1 AAA-like domain TrwB_AAD_bind PF10412.9 pNZ_AAFJ01000010_00064 - 5.1e-08 32.2 0.0 0.0045 15.9 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 pNZ_AAFJ01000010_00064 - 0.0013 19.1 0.4 2.3 8.5 0.0 3.2 2 1 0 3 3 3 2 AAA domain ResIII PF04851.15 pNZ_AAFJ01000010_00064 - 0.0024 17.9 2.1 0.057 13.4 0.2 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CbiA PF01656.23 pNZ_AAFJ01000010_00064 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zot PF05707.12 pNZ_AAFJ01000010_00064 - 0.014 15.1 0.0 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) TraG-D_C PF12696.7 pNZ_AAFJ01000010_00064 - 0.017 15.1 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG RsgA_GTPase PF03193.16 pNZ_AAFJ01000010_00064 - 0.056 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF1639 PF07797.14 pNZ_AAFJ01000010_00064 - 0.073 13.1 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) TrbI_Ftype PF09677.10 pNZ_AAFJ01000010_00065 - 0.028 14.7 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Peptidase_S26 PF10502.9 pNZ_AAFJ01000010_00066 - 1.6e-15 57.1 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 PRA-CH PF01502.18 pNZ_AAFJ01000010_00066 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase TraH PF06122.11 pNZ_AAFJ01000010_00067 - 5.3e-64 216.8 0.3 5.3e-64 216.8 0.3 1.6 2 0 0 2 2 2 1 Conjugative relaxosome accessory transposon protein ArfGap PF01412.18 pNZ_AAFJ01000010_00067 - 0.37 10.9 1.7 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf SAYSvFN PF10260.9 pNZ_AAFJ01000010_00068 - 0.046 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Ribosomal_L6e PF01159.19 pNZ_AAFJ01000010_00068 - 0.84 10.2 6.1 1.7 9.2 5.5 1.9 1 1 0 1 1 1 0 Ribosomal protein L6e TraN PF06986.11 pNZ_AAFJ01000010_00069 - 3.3e-26 92.5 26.5 9.2e-25 87.7 20.4 3.0 2 1 0 2 2 2 1 Type-1V conjugative transfer system mating pair stabilisation Lectin_C PF00059.21 pNZ_AAFJ01000010_00069 - 1.8e-05 25.4 0.0 1.8e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 Lectin C-type domain Xol-1_GHMP-like PF09109.10 pNZ_AAFJ01000010_00069 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like TraF PF13728.6 pNZ_AAFJ01000010_00070 - 3.2e-18 66.4 7.8 4.7e-18 65.8 7.8 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein PUA_2 PF14306.6 pNZ_AAFJ01000010_00070 - 0.015 15.0 0.3 0.028 14.1 0.3 1.6 1 0 0 1 1 1 0 PUA-like domain DUF2369 PF10179.9 pNZ_AAFJ01000010_00070 - 0.18 12.2 2.7 0.79 10.1 0.3 2.4 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2369) TraG_N PF07916.11 pNZ_AAFJ01000010_00071 - 3.7e-55 187.6 16.8 3.7e-55 187.6 16.8 1.9 2 1 0 2 2 2 1 TraG-like protein, N-terminal region TIM21 PF08294.11 pNZ_AAFJ01000010_00072 - 2.7 7.9 3.9 7.5 6.4 0.4 2.5 2 1 1 3 3 3 0 TIM21 YwiC PF14256.6 pNZ_AAFJ01000010_00072 - 2.9 8.2 13.6 0.14 12.5 1.5 2.9 2 1 1 3 3 3 0 YwiC-like protein T_cell_tran_alt PF15128.6 pNZ_AAFJ01000010_00072 - 3.6 7.4 10.0 0.69 9.7 2.2 2.8 1 1 2 3 3 3 0 T-cell leukemia translocation-altered Wzy_C PF04932.15 pNZ_AAFJ01000010_00073 - 0.086 12.5 0.1 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF4713 PF15831.5 pNZ_AAFJ01000010_00073 - 0.17 12.3 3.6 0.18 12.2 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) PFO_beta_C PF12367.8 pNZ_AAFJ01000010_00075 - 0.064 13.4 1.6 0.093 12.9 0.2 2.0 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Phage_Treg PF04761.12 pNZ_AAFJ01000010_00075 - 0.085 13.0 1.7 0.33 11.1 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator AAA_25 PF13481.6 pNZ_AAFJ01000010_00076 - 1.7e-18 66.9 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 pNZ_AAFJ01000010_00076 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DnaB_C PF03796.15 pNZ_AAFJ01000010_00076 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 pNZ_AAFJ01000010_00076 - 0.041 13.2 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 pNZ_AAFJ01000010_00076 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 pNZ_AAFJ01000010_00076 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.15 pNZ_AAFJ01000010_00076 - 0.23 11.4 2.5 1.2 9.1 2.4 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HTH_3 PF01381.22 pNZ_AAFJ01000010_00077 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 pNZ_AAFJ01000010_00077 - 1.2e-05 25.2 0.7 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TACC_C PF05010.14 pNZ_AAFJ01000010_00077 - 0.013 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal T3SchapCesA PF11439.8 pNZ_AAFJ01000010_00077 - 0.11 12.7 0.4 0.43 10.8 0.1 1.9 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA HTH_31 PF13560.6 pNZ_AAFJ01000010_00077 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Toprim_3 PF13362.6 pNZ_AAFJ01000010_00078 - 5.2e-09 36.3 0.0 8.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 pNZ_AAFJ01000010_00078 - 0.017 15.6 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 Toprim domain AAA_25 PF13481.6 pNZ_AAFJ01000010_00079 - 1e-15 57.8 0.0 2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 pNZ_AAFJ01000010_00079 - 0.0004 19.8 0.0 0.0041 16.5 0.0 2.1 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 pNZ_AAFJ01000010_00079 - 0.0014 18.3 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 pNZ_AAFJ01000010_00079 - 0.013 14.8 0.0 0.049 13.0 0.0 2.1 2 1 0 2 2 2 0 KaiC AAA PF00004.29 pNZ_AAFJ01000010_00079 - 0.07 13.6 0.1 0.91 10.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 pNZ_AAFJ01000010_00079 - 0.34 11.0 3.4 2.6 8.1 3.4 2.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SseC PF04888.12 pNZ_AAFJ01000010_00080 - 0.0012 18.6 1.4 0.0012 18.6 1.4 1.8 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Leu_Phe_trans PF03588.14 pNZ_AAFJ01000010_00080 - 0.034 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase T2SSF PF00482.23 pNZ_AAFJ01000010_00080 - 0.18 11.8 0.1 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3185 PF11381.8 pNZ_AAFJ01000010_00080 - 0.2 11.7 9.2 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2207 PF09972.9 pNZ_AAFJ01000010_00080 - 5.6 5.6 16.6 0.074 11.8 0.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Resolvase PF00239.21 pNZ_AAFJ01000010_00081 - 9.9e-36 123.0 0.2 1.4e-35 122.5 0.2 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain Mga PF05043.13 pNZ_AAFJ01000010_00081 - 0.012 16.1 2.2 0.15 12.7 0.6 2.5 2 0 0 2 2 2 0 Mga helix-turn-helix domain DUF2790 PF10976.8 pNZ_AAFJ01000010_00081 - 0.14 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) TrbC PF04956.13 pNZ_AAFJ01000010_00082 - 4.8e-15 55.6 8.1 5.6e-15 55.4 8.1 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family CagE_TrbE_VirB PF03135.14 pNZ_AAFJ01000010_00083 - 2.5e-43 148.6 0.5 6.2e-43 147.3 0.5 1.7 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 pNZ_AAFJ01000010_00083 - 1.2e-19 70.3 2.0 2.1e-19 69.5 2.0 1.4 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Phage_pRha PF09669.10 pNZ_AAFJ01000010_00084 - 2.7e-29 101.5 0.0 4.5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) T4SS PF07996.11 pNZ_AAFJ01000010_00085 - 2.3e-23 83.6 16.9 2.8e-23 83.4 16.9 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins CHASE4 PF05228.13 pNZ_AAFJ01000010_00085 - 0.05 13.8 5.7 1 9.6 0.2 2.9 2 1 1 3 3 3 0 CHASE4 domain KMP11 PF03037.16 pNZ_AAFJ01000010_00085 - 0.074 13.8 2.3 0.31 11.8 0.0 2.9 1 1 3 4 4 4 0 Kinetoplastid membrane protein 11 AChE_tetra PF08674.10 pNZ_AAFJ01000010_00085 - 0.099 12.4 1.2 0.5 10.1 0.1 2.2 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain zf-RING_6 PF14835.6 pNZ_AAFJ01000010_00085 - 0.12 12.2 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Med8 PF10232.9 pNZ_AAFJ01000010_00085 - 0.22 11.1 9.0 0.022 14.4 3.9 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PCRF PF03462.18 pNZ_AAFJ01000010_00085 - 0.25 11.2 11.7 2.7 7.8 0.4 2.2 2 0 0 2 2 2 0 PCRF domain TrbL PF04610.14 pNZ_AAFJ01000010_00086 - 5.9e-33 114.4 25.5 8.1e-33 114.0 25.5 1.3 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein DUF2070 PF09843.9 pNZ_AAFJ01000010_00086 - 0.31 9.3 16.7 0.47 8.7 16.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AIM3 PF17096.5 pNZ_AAFJ01000010_00086 - 5.4 8.0 7.0 9.6 7.2 7.0 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF412 PF04217.13 pNZ_AAFJ01000010_00086 - 6.5 6.7 10.8 20 5.1 6.7 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF412 VirB8 PF04335.13 pNZ_AAFJ01000010_00089 - 8.4e-50 169.6 0.1 1e-49 169.3 0.1 1.0 1 0 0 1 1 1 1 VirB8 protein Wzz PF02706.15 pNZ_AAFJ01000010_00089 - 2.4 8.5 6.7 2.8 8.3 3.2 2.5 2 1 0 2 2 2 0 Chain length determinant protein CagX PF03524.15 pNZ_AAFJ01000010_00090 - 2.3e-53 181.1 0.8 4.6e-53 180.1 0.8 1.5 1 1 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 pNZ_AAFJ01000010_00091 - 1.3e-46 158.8 0.1 1.3e-46 158.8 0.1 1.6 2 0 0 2 2 2 1 Bacterial conjugation TrbI-like protein DUF5345 PF17280.2 pNZ_AAFJ01000010_00091 - 0.17 11.8 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5345) MORN_2 PF07661.13 pNZ_AAFJ01000010_00092 - 0.39 11.1 2.9 2.8 8.4 0.6 2.8 2 0 0 2 2 2 0 MORN repeat variant Ribosomal_S13 PF00416.22 pNZ_AAFJ01000010_00092 - 0.83 10.1 4.2 17 5.8 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S13/S18 T2SSE PF00437.20 pNZ_AAFJ01000010_00093 - 5.1e-54 183.2 0.0 6.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 pNZ_AAFJ01000010_00093 - 4.9e-05 23.6 0.0 9.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 pNZ_AAFJ01000010_00093 - 0.00012 22.6 0.0 0.00029 21.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 pNZ_AAFJ01000010_00093 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 pNZ_AAFJ01000010_00093 - 0.00062 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 pNZ_AAFJ01000010_00093 - 0.0028 18.2 1.3 0.0028 18.2 1.3 1.9 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 pNZ_AAFJ01000010_00093 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 pNZ_AAFJ01000010_00093 - 0.003 17.0 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_15 PF13175.6 pNZ_AAFJ01000010_00093 - 0.0035 17.1 2.5 0.0035 17.1 2.5 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 pNZ_AAFJ01000010_00093 - 0.0041 16.9 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 pNZ_AAFJ01000010_00093 - 0.0043 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.22 pNZ_AAFJ01000010_00093 - 0.012 16.0 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 pNZ_AAFJ01000010_00093 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 pNZ_AAFJ01000010_00093 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 pNZ_AAFJ01000010_00093 - 0.015 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 pNZ_AAFJ01000010_00093 - 0.015 15.4 1.0 0.03 14.4 0.2 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 pNZ_AAFJ01000010_00093 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 pNZ_AAFJ01000010_00093 - 0.021 14.6 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 pNZ_AAFJ01000010_00093 - 0.023 14.1 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 pNZ_AAFJ01000010_00093 - 0.027 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 pNZ_AAFJ01000010_00093 - 0.045 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 pNZ_AAFJ01000010_00093 - 0.046 12.6 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 pNZ_AAFJ01000010_00093 - 0.051 13.6 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.15 pNZ_AAFJ01000010_00093 - 0.055 13.5 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SMC_N PF02463.19 pNZ_AAFJ01000010_00093 - 0.063 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 pNZ_AAFJ01000010_00093 - 0.07 12.9 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 pNZ_AAFJ01000010_00093 - 0.073 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 pNZ_AAFJ01000010_00093 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 pNZ_AAFJ01000010_00093 - 0.09 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 pNZ_AAFJ01000010_00093 - 0.091 12.8 0.3 0.21 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain GvpD PF07088.11 pNZ_AAFJ01000010_00093 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein Sigma54_activat PF00158.26 pNZ_AAFJ01000010_00093 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 pNZ_AAFJ01000010_00093 - 0.12 12.6 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 pNZ_AAFJ01000010_00093 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain YscJ_FliF PF01514.17 pNZ_AAFJ01000010_00094 - 0.019 14.7 2.6 0.31 10.7 0.1 2.4 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Njmu-R1 PF15053.6 pNZ_AAFJ01000010_00094 - 0.028 13.5 1.6 0.051 12.7 1.6 1.4 1 0 0 1 1 1 0 Mjmu-R1-like protein family FtsQ PF03799.15 pNZ_AAFJ01000010_00094 - 0.18 12.7 0.8 1.8 9.4 0.0 2.4 3 0 0 3 3 3 0 Cell division protein FtsQ Halogen_Hydrol PF10112.9 pNZ_AAFJ01000010_00094 - 1.1 9.2 6.9 4.3 7.3 0.8 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Flagellin_N PF00669.20 pNZ_AAFJ01000010_00094 - 2.1 8.5 7.4 1.9 8.6 0.4 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region SlyX PF04102.12 pNZ_AAFJ01000010_00094 - 2.2 9.0 7.3 4.6 7.9 0.8 2.6 3 0 0 3 3 2 0 SlyX DUF1664 PF07889.12 pNZ_AAFJ01000010_00094 - 2.4 8.2 10.7 3.9 7.5 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 pNZ_AAFJ01000010_00094 - 5.7 7.4 10.3 4 7.9 0.5 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HrpB7 PF09486.10 pNZ_AAFJ01000010_00094 - 5.9 7.3 7.8 1.6 9.1 0.6 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Vac_Fusion PF02346.16 pNZ_AAFJ01000010_00094 - 6 6.6 7.8 1.2 8.8 0.8 2.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 FapA PF03961.13 pNZ_AAFJ01000010_00094 - 6.9 5.2 21.5 0.11 11.0 9.9 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A BST2 PF16716.5 pNZ_AAFJ01000010_00094 - 6.9 7.3 17.4 1.4 9.6 3.4 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 T4SS-DNA_transf PF02534.14 pNZ_AAFJ01000010_00095 - 1.3e-109 367.1 0.0 1.8e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 pNZ_AAFJ01000010_00095 - 6.2e-27 94.1 0.0 1.1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 pNZ_AAFJ01000010_00095 - 1.4e-18 67.0 0.0 3.3e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain BRI3BP PF14965.6 pNZ_AAFJ01000010_00095 - 0.22 11.0 2.3 0.26 10.8 1.2 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Cag12 PF13117.6 pNZ_AAFJ01000010_00096 - 1.1e-16 61.2 0.1 1.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein Cag12 LPAM_2 PF13627.6 pNZ_AAFJ01000010_00096 - 0.027 14.3 3.2 0.044 13.6 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF5061 PF16587.5 pNZ_AAFJ01000010_00096 - 0.15 12.2 0.1 0.19 11.8 0.1 1.3 1 1 0 1 1 1 0 17 kDa common-antigen outer membrane protein TrbM PF07424.11 pNZ_AAFJ01000010_00097 - 6.3e-39 133.4 1.3 8e-39 133.1 1.3 1.1 1 0 0 1 1 1 1 TrbM Latarcin PF10279.9 pNZ_AAFJ01000010_00098 - 0.016 15.6 1.6 0.66 10.4 1.6 3.5 1 1 0 1 1 1 0 Latarcin precursor Lipase_GDSL PF00657.22 pNZ_AAFJ01000010_00098 - 0.033 14.2 1.1 0.067 13.2 0.9 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase T3SS_basalb_I PF17001.5 pNZ_AAFJ01000010_00098 - 0.078 13.6 4.2 1.7 9.3 0.5 2.8 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cor1 PF04803.12 pNZ_AAFJ01000010_00098 - 0.15 12.3 22.3 0.15 12.2 6.2 3.3 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1451 PF07295.11 pNZ_AAFJ01000010_00098 - 0.25 11.3 8.8 0.2 11.7 2.5 2.5 1 1 2 3 3 3 0 Zinc-ribbon containing domain TipAS PF07739.13 pNZ_AAFJ01000010_00098 - 0.36 11.4 6.4 9 6.9 0.2 3.3 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Exonuc_VII_L PF02601.15 pNZ_AAFJ01000010_00098 - 0.37 10.3 10.9 0.65 9.5 2.7 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.14 pNZ_AAFJ01000010_00098 - 2.8 8.3 16.8 3.5 8.0 3.1 2.8 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Topoisom_bac PF01131.20 pNZ_AAFJ01000010_00100 - 4.4e-96 322.4 2.6 5.6e-96 322.1 2.6 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 pNZ_AAFJ01000010_00100 - 8.4e-12 45.2 0.4 3.4e-11 43.3 0.1 2.3 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 pNZ_AAFJ01000010_00100 - 1.2e-07 31.3 19.1 0.00081 19.1 3.8 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 pNZ_AAFJ01000010_00100 - 0.00043 20.5 0.2 0.69 10.2 0.0 2.5 2 0 0 2 2 2 2 zinc-ribbon Zn_ribbon_SprT PF17283.2 pNZ_AAFJ01000010_00100 - 0.014 15.3 1.1 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Toprim_2 PF13155.6 pNZ_AAFJ01000010_00100 - 0.036 14.5 0.3 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 Toprim-like HTH_34 PF13601.6 pNZ_AAFJ01000010_00100 - 0.074 13.2 0.5 0.77 10.0 0.1 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain Zn-ribbon_8 PF09723.10 pNZ_AAFJ01000010_00100 - 0.077 13.1 0.7 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 pNZ_AAFJ01000010_00100 - 0.11 12.4 2.3 11 6.1 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Toprim_4 PF13662.6 pNZ_AAFJ01000010_00100 - 0.12 12.8 0.1 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 Toprim domain zf-ribbon_3 PF13248.6 pNZ_AAFJ01000010_00100 - 0.18 11.3 1.0 12 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TRAF6_Z2 PF18048.1 pNZ_AAFJ01000010_00100 - 0.44 10.7 3.7 1.1 9.4 0.4 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn_Tnp_IS1 PF03811.13 pNZ_AAFJ01000010_00100 - 0.46 10.2 3.3 5.1 6.9 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain zf-HIT PF04438.16 pNZ_AAFJ01000010_00100 - 0.48 10.3 4.2 5.9 6.8 0.4 2.6 2 0 0 2 2 2 0 HIT zinc finger zf_C2H2_10 PF18414.1 pNZ_AAFJ01000010_00100 - 2.6 7.7 7.4 11 5.7 1.3 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger PIN_4 PF13638.6 pNZ_AAFJ01000010_00100 - 6 7.2 6.6 0.81 10.0 1.0 2.4 3 0 0 3 3 3 0 PIN domain zf-